Dr Abid Hussain

Research Associate Future Industries Institute

Mawson Lakes Campus ()
tel +61 8 830 23929

mob 0459328343
email Abid.Hussain@unisa.edu.au

Alternative contact

Research Degree Supervisor

About me

mRNA therapeutics, LNPs, Polymeric NPs

Abid Hussain is an emerging scientist holding a Ph.D. in Drug Delivery, specialized in nano-medicines for cancer therapy.

Having served as a formulation manager in a renowned pharmaceutical industry, he has contributed to the development of three patents, registered with WIPO and protected under PCT. Additionally, played a pivotal role in the submission process of two pharmaceutical products to EMA during 2020-2021.

Furthermore, his expertise extends to nucleic acid therapeutics for treating tumors, hyperlipidemia, and hyperuricemia. He has authored numerous publications in prestigious journals, serving as the first author, co-author, and corresponding author. These publications have garnered over 1000 citations, with an... Read more

Future Industries Institute

The Institute partners with today’s industries, to create the industries of tomorrow.

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Orcid
Scopus

Research

Research focus

Biomedical Engineering
Biochemistry and Cell Biology
Chemical Sciences
Pharmacology and Pharmaceutical Sciences
Technology

Highlights

Abid Hussain is an emerging scientist holding a Ph.D. in Drug Delivery, specialized in nano-medicines for cancer therapy.

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Highlights

Year	Output
2024	Zhang, M, Hussain, A, Hu, B, Yang, H, Li, C, Guo, S, Han, X, Li, B, Dai, Y, Cao, Y, Chi, H, Weng, Y, Qin, C-F & Huang, Y 2024, 'Atavistic strategy for the treatment of hyperuricemia via ionizable liposomal mRNA', Nature Communications, vol.15, no. 1, pp. 1-16. Open access 7 7
2023	Zhang, M, Hussain, A, Yang, H, Zhang, J, Liang, XJ & Huang, Y 2023, 'mRNA-based modalities for infectious disease management', Nano Research, vol. 16, no. 1, pp. 672-691. 15 15 20
2022	Hu, B, Hussain, A, Liu, Q, Weng, Y & Huang, Y 2022, 'Advances in mRNA delivery and clinical applications', in Stefan Jurga & Jan Barciszewski (eds), Messenger RNA Therapeutics, Springer, Switzerland, ch. 13, pp. 277-305. 1
2022	Hu, B, Li, B, Li, K, Liu, Y, Li, C, Zheng, L, Zhang, M, Yang, T, Guo, S, Dong, X, Zhang, T, Liu, Q, Hussain, A, Weng, Y, Peng, L, Zhao, Y, Liang, XJ & Huang, Y 2022, 'Thermostable ionizable lipid-like nanoparticle (iLAND) for RNAi treatment of hyperlipidemia', Science Advances, vol. 8, no. 7, article no. eabm1418, pp. 1-18. Open access 65 67 3
2022	Hussain, A, Yang, H, Zhang, M, Liu, Q, Alotaibi, G, Irfan, M, He, H, Chang, J, Liang, XJ, Weng, Y & Huang, Y 2022, 'mRNA vaccines for COVID-19 and diverse diseases', Journal of Controlled Release, vol. 345, pp. 314-333. 86 69 12

Chapters

Year	Output
2022	Hu, B, Hussain, A, Liu, Q, Weng, Y & Huang, Y 2022, 'Advances in mRNA delivery and clinical applications', in Stefan Jurga & Jan Barciszewski (eds), Messenger RNA Therapeutics, Springer, Switzerland, ch. 13, pp. 277-305. 1
2022	Hussain, A, Weng, Y & Huang, Y 2022, 'Graphene and graphene-based nanomaterials: current applications and future perspectives', in Yasser Shahzad et al. (eds), Drug Delivery Using Nanomaterials, CRC Press, US, ch. 9, pp. 209-228. 5
2022	Sohail, M, Rabbi, F, Younas, A, Hussain, A, Yu, B, Li, Y, Iqbal, S, Ullah, KH, Qadeer, A, Aquib, M, Iqbal, H & Xu, H 2022, 'Herbal bioactive-based nano drug delivery systems', in IS Bakshi, R Bala & RK Sindhu (eds), Herbal Bioactive-Based Drug Delivery Systems: Challenges and Opportunities, Elsevier, UK, ch. 6, pp. 169-193. 7

Journal Articles

Year	Output
2024	Zhang, M, Hussain, A, Hu, B, Yang, H, Li, C, Guo, S, Han, X, Li, B, Dai, Y, Cao, Y, Chi, H, Weng, Y, Qin, C-F & Huang, Y 2024, 'Atavistic strategy for the treatment of hyperuricemia via ionizable liposomal mRNA', Nature Communications, vol.15, no. 1, pp. 1-16. Open access 7 7
2023	Hu, B, Kong, S, Weng, Y, Zhao, D, Hussain, A, Jiao, Q, Zhan, S, Qiu, L, Lin, J, Xie, M, Li, B & Huang, Y 2023, 'Lipid-conjugated siRNA hitchhikes endogenous albumin for tumor immunotherapy', Chinese Chemical Letters, vol. 34, no. 11, article no. 108210, pp. 1-7. 8 8 4
2023	Zhang, M, Hussain, A, Yang, H, Zhang, J, Liang, XJ & Huang, Y 2023, 'mRNA-based modalities for infectious disease management', Nano Research, vol. 16, no. 1, pp. 672-691. 15 15 20
2022	Hu, B, Li, B, Li, K, Liu, Y, Li, C, Zheng, L, Zhang, M, Yang, T, Guo, S, Dong, X, Zhang, T, Liu, Q, Hussain, A, Weng, Y, Peng, L, Zhao, Y, Liang, XJ & Huang, Y 2022, 'Thermostable ionizable lipid-like nanoparticle (iLAND) for RNAi treatment of hyperlipidemia', Science Advances, vol. 8, no. 7, article no. eabm1418, pp. 1-18. Open access 65 67 3
2022	Hussain, A, Yang, H, Zhang, M, Liu, Q, Alotaibi, G, Irfan, M, He, H, Chang, J, Liang, XJ, Weng, Y & Huang, Y 2022, 'mRNA vaccines for COVID-19 and diverse diseases', Journal of Controlled Release, vol. 345, pp. 314-333. 86 69 12
2022	Irfan, M, Shahid, AL, Ahmad, M, Iqbal, W, Elavarasan, RM, Ren, S & Hussain, A 2022, 'Assessment of public intention to get vaccination against COVID-19: Evidence from a developing country', Journal of Evaluation in Clinical Practice, vol. 28, no. 1, pp. 63-73. 54 58 8
2022	Li, C, Yang, T, Weng, Y, Zhang, M, Zhao, D, Guo, S, Hu, B, Shao, W, Wang, X, Hussain, A, Liang, XJ & Huang, Y 2022, 'Ionizable lipid-assisted efficient hepatic delivery of gene editing elements for oncotherapy', Bioactive Materials, vol. 9, pp. 590-601. Open access 56 52 4
2022	Tuguntaev, RG, Hussain, A, Fu, C, Chen, H, Tao, Y, Huang, Y, Liu, L, Liang, XJ & Guo, W 2022, 'Bioimaging guided pharmaceutical evaluations of nanomedicines for clinical translations', Journal of Nanobiotechnology, vol. 20, no. 1, article no. 236, pp. 1-31. Open access 17 12
2022	Ullah, A, Chen, G, Yibang, Z, Hussain, A, Shafiq, M, Raza, F, Liu, D, Wang, K, Cao, J & Qi, X 2022, 'A new approach based on CXCR4-targeted combination liposomes for the treatment of liver fibrosis', Biomaterials Science, vol. 10, no. 10, pp. 2650-26644. 14 13 1
2022	Xu, M, Mao, C, Chen, H, Liu, L, Wang, Y, Hussain, A, Li, S, Zhang, X, Tuguntaev, RG, Liang, XJ, Guo, W & Cao, F 2022, 'Osteopontin targeted theranostic nanoprobes for laser-induced synergistic regression of vulnerable atherosclerotic plaques', Acta Pharmaceutica Sinica B, vol. 12, no. 4, pp. 2014-2028. Open access 20 16 1
2022	Yu, C, Li, K, Xu, L, Li, B, Li, C, Guo, S, Li, Z, Zhang, Y, Hussain, A, Tan, H, Zhang, M, Zhao, Y, Huang, Y & Liang, XJ 2022, 'siRNA-functionalized lanthanide nanoparticle enables efficient endosomal escape and cancer treatment', Nano Research, vol. 25, no. 10, pp. 9160-9168. 14 14 11
2021	Guo, S, Li, K, Hu, B, Li, C, Zhang, M, Hussain, A, Wang, X, Cheng, Q, Yang, F, Ge, K, Zhang, J, Chang, J, Liang, XJ, Weng, Y & Huang, Y 2021, 'Membrane-destabilizing ionizable lipid empowered imaging-guided siRNA delivery and cancer treatment', Exploration, vol. 1, no. 1, pp. 35-49. Open access 138
2021	Li, C, Zhou, J, Wu, Y, Dong, Y, Du, L, Yang, T, Wang, Y, Guo, S, Zhang, M, Hussain, A, Xiao, H, Weng, Y, Huang, Y, Wang, X, Liang, Z, Cao, H, Zhao, Y, Liang, XJ, Dong, A & Huang, Y 2021, 'Core role of hydrophobic core of polymeric nanomicelle in edosomal escape of siRNA', Nano Letters: A Journal Dedicated to Nanoscience and Nanotechnology, vol. 21, no. 8, pp. 3680-3689. 78 77
2021	Li, K, Zhang, Y, Hussain, A, Weng, Y & Huang, Y 2021, 'Progress of photodynamic and RNAi combination therapy in cancer treatment', ACS Biomaterial Science and Engineering, vol. 7, no. 9, pp. 44200-4429. 22 21 3
2021	Ullah, A, Chen, G, Hussain, A, Khan, H, Abbas, A, Zhou, Z, Shafiq, M, Ahmad, S, Ali, U, Usman, M, Raza, F, Ahmed, A, Qiu, Z, Zheng, M & Liu, D 2021, 'Cyclam-modified polyethyleneimine for simultaneous tgfβ sirna delivery and cxcr4 inhibition for the treatment of ccl₄ induced liver fibrosis', International Journal of Nanomedicine, vol. 16, pp. 4451-4470. Open access 16 16 2
2019	Hussain, A & Guo, S 2019, 'NIR-triggered release of DOX from sophorolipid-coated mesoporous carbon nanoparticles with the phase-change material 1-tetradecanol to treat MCF-7/ADR cells', Journal of Materials Chemistry B, vol. 7, no. 6, pp. 974-985. 25 24 1
2019	Khan, MT, Junaid, M, Mao, X, Wang, Y, Hussain, A, Malik, SI & Wei, DQ 2019, 'Pyrazinamide resistance and mutations L19R, R140H, and E144K in Pyrazinamidase of Mycobacterium tuberculosis', Journal of Cellular Biochemistry, vol. 120, no. 5, pp. 7154-7166. 16 15 1
2017	Huang, S, Liu, J, Zhu, H, Hussain, A, Liu, Q, Li, J, Shen, Y, Cheng, J & Guo, S 2017, 'PEGylated doxorubicin micelles loaded with curcumin exerting synergic effects on multidrug resistant tumor cells', Journal of Nanoscience and Nanotechnology, vol. 17, no. 5, pp. 2873-2880. 14 13
2017	Zhang, Z, Wang, Y, Xu, S, Yu, Y, Hussain, A, Shen, Y & Guo, S 2017, 'Photothermal gold nanocages filled with temperature sensitive tetradecanol and encapsulated with glutathione responsive polycurcumin for controlled DOX delivery to maximize anti-MDR tumor effects', Journal of Materials Chemistry B, vol. 5, no. 27, pp. 5464-5472. 30 28 1
2017	Zhu, H, Wang, Y, Hussain, A, Zhang, Z, Shen, Y & Guo, S 2017, 'Nanodiamond mediated co-delivery of doxorubicin and malaridine to maximize synergistic anti-tumor effects on multi-drug resistant MCF-7/ADR cells', Journal of Materials Chemistry B, vol. 5, no. 19, pp. 3531-3540. 31 25 6
2016	Ullah, F, Ayaz, M, Sadiq, A, Hussain, A, Ahmad, S, Imran, M & Zeb, A 2016, 'Phenolic, flavonoid contents, anticholinesterase and antioxidant evaluation of Iris germanica var; florentina', Natural Product Research, vol. 30, no. 12, pp. 1440-1444. 73 63 3

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Abasyn University	PAKISTAN
Affiliated Hospital of Nantong University	CHINA
Aix-Marseille University	FRANCE
Beijing Institute of Microbiology and Epidemiology	CHINA
Beijing Institute of Technology	CHINA
Capital University of Science and Technology	PAKISTAN
China Pharmaceutical University	CHINA
Chinese Academy of Sciences	CHINA
Chinese PLA General Hospital	CHINA
Guangxi Medical University	CHINA
Guangzhou Medical University	CHINA
Hebei University	CHINA
Henan Normal University	CHINA
Jiangnan University	CHINA
Jiangsu University	CHINA
Nankai University	CHINA
Nantong University	CHINA
National Center for Nanoscience and Technology of China	CHINA
Nestlives Private Limited	INDIA
Peking University	CHINA
Quaid-i-Azam University	PAKISTAN
Shandong University	CHINA
Shanghai Jiao Tong University	CHINA
Shanghai University	CHINA
Shanghai Veterinary Research Institute	CHINA
Shantou University	CHINA
Shantou University Medical College	CHINA
Shaqra University	SAUDI ARABIA
Shenzhen University	CHINA
Soochow University	CHINA
Tianjin Medical University	CHINA
Tianjin University	CHINA
University of California	UNITED STATES
University of Macau	MACAU (SAR OF CHINA)
University of Malakand	PAKISTAN
University of Texas Southwestern Medical Center	UNITED STATES
Women's and Children's Hospital	AUSTRALIA
Yangzhou University	CHINA
Yantai University	CHINA
Zhejiang University	CHINA
Zhengzhou University	CHINA

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
111875-Turning foes into allies: Hijacking myofibroblasts to regenerate cardiac tissues with RNA therapeutics	Current

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Dr Abid Hussain

Alternative contact

Alternative contact details

About me

About me

Future Industries Institute

About me

Professional Associations

Experience

Qualifications

Work history

Research

Research focus

Highlights

Projects

Outputs

Highlights

Chapters

Journal Articles

Current research & highlights

External engagement & recognition

Collaborations

Collaborations

Teaching & student supervision

Courses and programs

Research degree supervision

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