Mr David Lawrence

Senior Bioinformatician Centre for Cancer Biology

email David.Lawrence@unisa.edu.au

Research

Research focus

Biological Sciences
Medical and Health Sciences
Information and Computing Sciences
Environmental Sciences
Multidisciplinary

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID

Open access indicates that an output is open access.

Journal Articles

Year	Output
2025	Toubia, J, Kusay, Y, Maqsood, M, Warnock, N I, Lawrence, DM, Bracken, CP, Gregory, PA, Kan, WL, Selth, LA, Conn, SJ, Lopez, AF, Branford, S, Scott, HS, Kok, CH, Goodall, GJ & Schreiber, AW 2025, 'TRanscriptome ANalysis of StratifiEd CohorTs (TRANSECT) enables automated assessment of global gene regulation linked to disparate expression in user defined genes and gene sets', NAR Genomics and Bioinformatics, vol. 7, no. 2, article no. lqaf041, pp. 1-13. Open access
2023	Byrne, AB, Arts, P, Ha, TT, Kassahn, KS, Babic, M, Frank, MS, Feng, J, Wang, P, Lawrence, DM, Eshraghi, L, Arriola, L, Toubia, J, Gardner, AE, Morrow, R, Schreiber, AW, King-Smith, SL, Jackson, MR & Scott, HS 182 other authors and 2 consortia 2023, 'Genomic autopsy to identify underlying causes of pregnancy loss and perinatal death', Nature Medicine, vol. 29, no. 1, pp. 180-189. Open access 43 39 76
2023	Homan, CC, Drazer, MW, Yu, K, Lawrence, DM, Feng, J, Arriola-Martinez, LA, Ha, TT, Venugopal, P, Arts, P, King-Smith, S, Cheah, JJC, Armstrong, M, Wang, P, Babic, M, Scott, HS & Brown, AL and 49 other authors 2023, 'Somatic mutational landscape of hereditary hematopoietic malignancies caused by germ line RUNX1, GATA2, and DDX41 variants', Blood Advances, vol. 7, no. 20, pp. 6092-6107. Open access 29 25 3
2022	Drazer, MW, Homan, CC, Yu, K, de Andrade Silva, M, Feng, J, King-Smith, SL, Lawrence, DM, Schreiber, AW, Hahn, CN, Scott, HS, Brown, AL & Godley, LA and 10 other authors & 1 consortia 2022, 'Clonal hematopoiesis in patients with ANKRD26 or ETV6 germline mutations.', Blood Advances, vol. 6, no. 15, pp. 4357-4359. Open access 21 21 4
2022	Tudini, E, Andrews, J, Lawrence, DM, King-Smith, SL, Schreiber, AW & James, U and 54 other authors & 1 Consortia 2022, 'Shariant platform: Enabling evidence sharing across Australian clinical genetic-testing laboratories to support variant interpretation', American Journal of Human Genetics, vol. 109, no. 11, pp. 1960-1973. 22 20
2018	Pillman, KA, Phillips, CA, Roslan, S, Toubia, J, Dredge, BK, Bert, AG, Lumb, R, Neumann, DP, Li, X, Conn, SJ, Liu, D, Bracken, CP, Lawrence, DM, Schreiber, AW, Khew-Goodall, Y, Goodall, GJ & Gregory, PA and 4 other authors 2018, 'miR‐200/375 control epithelial plasticity‐associated alternative splicing by repressing the RNA‐binding protein Quaking', The EMBO Journal, vol. 37, no. 13, article no. e99016, pp. 1-20. Open access 89 88 15
2017	Lumb, R, Buckberry, S, Secker, G, Lawrence, DM & Schwarz, Q 2017, 'Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels', BMC Developmental Biology, vol. 17, article no. 5, pp. 1-12. Open access 20 20 2
2017	Yu, F, Pillman, KA, Neilsen, CT, Toubia, J, Lawrence, DM, Tsykin, A, Gantier, MP, Callen, DF, Goodall, GJ & Bracken, CP 2017, 'Naturally existing isoforms of miR-222 have distinct functions', Nucleic Acids Research, vol. 45, no. 19, pp. 1137-11385. Open access 63 59 7
2014	Bracken, CP, Li, X, Wright, JA, Lawrence, DM, Pillman, KA, Salmanidis, M, Anderson, MA, Dredge, BK, Gregory, PA, Tsykin, A, Neilsen, C, Thomson, DW, Bert, AG, Leerberg, JM, Yap, AS, Jensen, KB, Khew-Goodall, Y & Goodall, GJ 2014, 'Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion', The EMBO Journal, vol. 33, no. 18, pp. 2040-2056. Open access 124 121
2013	Attema, JL, Bert, AG, Lim, Y-Y, Kolesnikoff, N, Lawrence, DM, Pillman, KA, Smith, E, Drew, PA, Khew-Goodall, Y, Shannon, F & Goodall, GJ 2013, 'Identification of an enhancer that increases miR-200b~429 gene expression in breast cancer cells', PLoS One, vol. 8, no. 9, pp. 1-15. Open access 21 19
2013	Pishas, K I, Neuhaus, SJ, Clayer, MT, Schreiber, AW, Lawrence, DM, Perugini, M, Whitfield, RJ, Farshid, G, Manavis, J, Chyrssidis, S, Mayo, BJ, Haycox, RC, Ho, K, Brown, MP, D'Andrea, RJ, Evdokiou, A, Thomas, DM, Desai, J, Callen, DF & Neilsen, PM 2013, 'Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling', Cancer Research, vol. 74, no. 3, pp. 1-11. 22 22

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Australian Genomics Health Alliance	AUSTRALIA
Central Queensland University	AUSTRALIA
Federal University of Alagoas	BRAZIL
Flinders University	AUSTRALIA
Hanson Institute	AUSTRALIA
Harry Perkins Institute of Medical Research	AUSTRALIA
Melbourne Genomics Health Alliance	AUSTRALIA
Monash University	AUSTRALIA
National Human Genome Research Institute	UNITED STATES
National Institutes of Health	MALAYSIA
Peter MacCallum Cancer Centre	AUSTRALIA
Royal Adelaide Hospital	AUSTRALIA
Royal Melbourne Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
The Queen Elizabeth Hospital	AUSTRALIA
University of Adelaide	AUSTRALIA
University of Canberra	AUSTRALIA
University of Chicago	UNITED STATES
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA

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Mr David Lawrence

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Research

Research focus

Projects

Outputs

Journal Articles

External engagement & recognition

Collaborations

Collaborations

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