Dr Helen Palethorpe

Research Associate Centre for Cancer Biology

City West Campus ()
tel +61 8 830 20076

email Helen.Palethorpe@unisa.edu.au

Research

Research focus

Biochemistry and Cell Biology
Clinical Sciences
Genetics
Biological Sciences
Medical Biochemistry and Metabolomics

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Journal Articles

Year	Output
2025	Skarne, N, D'Souza, RC, Palethorpe, HM, Bradbrook, KA, Gomez, GA & Day, BW 2025, 'Personalising glioblastoma medicine: explant organoid applications, challenges and future perspectives', Acta Neuropathologica Communications, vol. 13, no. 1, article 6, pp. 1-14. Open access 1 1 3
2024	Neumann, DP, Phillips, CA, Lumb, R, Palethorpe, HM, Ramani, Y, Hollier, BG, Selth, LA, Bracken, CP, Goodall, GJ & Gregory, PA 2024, 'Quaking isoforms cooperate to promote the mesenchymal phenotype', Molecular Biology of the Cell, vol. 35, no. 2, pp. 1-17. Open access 2
2021	Nakhjavani, M, Smith, E, Palethorpe, HM, Tomita, Y, Yeo, K, Price, TJ, Townsend, AR & Hardingham, JE 2021, 'Anti-cancer effects of an optimised combination of ginsenoside rg3 epimers on triple negative breast cancer models', Pharmaceuticals, vol. 14, no. 7, article no. 633, pp. 1-20. Open access 12 11 1
2021	Nakhjavani, M, Smith, E, Yeo, K, Palethorpe, HM, Tomita, Y, Price, TJ, Townsend, AR & Hardingham, JE 2021, 'Anti-angiogenic properties of ginsenoside rg3 epimers: in vitro assessment of single and combination treatments', Cancers, vol. 13, no. 9, article no. 2223, pp. 1-20. Open access 21 19
2019	Nakhjavani, M, Hardingham, J, Palethorpe, H, Price, TJ & Townsend, AR 2019, 'Druggable Molecular Targets for the Treatment of Triple Negative Breast Cancer', Journal of Breast Cancer, vol. 22, no. 3, pp. 341-361. Open access 44 44 3
2019	Nakhjavani, M, Hardingham, JE, Palethorpe, HM, Tomita, Y, Smith, E, Price, TJ & Townsend, AR 2019, 'Ginsenoside Rg3: potential molecular targets and therapeutic indication in metastatic breast cancer', Medicines, vol. 6, no. 1, pp. 1-20. Open access
2019	Nakhjavani, M, Palethorpe, HM, Tomita, Y, Smith, E, Price, TJ, Yool, AJ, Pei, J V, Townsend, AR & Hardingham, JE 2019, 'Stereoselective anti-cancer activities of Ginsenoside Rg3 on triple negative breast cancer cell models', Pharmaceuticals, vol. 12, no. 3, article no. 117, pp. 1-14. Open access 43 36 3
2019	Smith, E, Tomita, Y, Palethorpe, HM, Howell, S, Nakhjavani, M, Townsend, AR, Price, TJ, Young, JP & Hardingham, JE 2019, 'Reduced aquaporin-1 transcript expression in colorectal carcinoma is associated with promoter hypermethylation', Epigenetics, vol. 14, no. 2, pp. 158-170. Open access 10 9 1
2019	Tomita, Y, Palethorpe, HM, Smith, E, Nakhjavani, M, Townsend, AR, Price, TJ, Yool, AJ & Hardingham, JE 2019, 'Bumetanide-derived aquaporin 1 inhibitors, Aqb013 and Aqb050 inhibit tube formation of endothelial cells through induction of apoptosis and impaired migration in vitro', International Journal of Molecular Sciences, vol. 20, no. 8, pp. 1-11. Open access 19 21 2
2018	Palethorpe, HM, Leach, DA, Need, EF, Drew, PA & Smith, E 2018, 'Myofibroblast androgen receptor expression determines cell survival in co-cultures of myofibroblasts and prostate cancer cells in vitro', Oncotarget, vol. 9, no. 27, pp. 19100-19114. Open access 11
2018	Palethorpe, HM, Tomita, Y, Smith, E, Pei, J V, Townsend, AR, Price, TJ, Young, JP, Yool, AJ & Hardingham, JE 2018, 'The aquaporin 1 inhibitor bacopaside II reduces endothelial cell migration and tubulogenesis and induces apoptosis', International Journal of Molecular Sciences, vol. 19, no. 3, article number 653, pp. 1-10. Open access 30 30 1
2018	Smith, E, Palethorpe, HM, Tomita, Y, Pei, J V, Townsend, AR, Price, TJ, Young, JP, Yool, AJ & Hardingham, JE 2018, 'The purified extract from the medicinal plant Bacopa monnieri, Bacopaside II, inhibits growth of colon cancer cells in vitro by inducing cell cycle arrest and apoptosis', Cells, vol. 7, no. 7, pp. 1-11. Open access 51 46 5
2017	Palethorpe, HM, Drew, PA & Smith, E 2017, 'Androgen signaling in esophageal adenocarcinoma cell lines in vitro', Digestive Diseases and Sciences, vol. 62, no. 12, pp. 3402-3414. Open access 21 22
2017	Smith, E, Palethorpe, HM, Hayden, AL, Young, JP, Underwood, TJ & Drew, PA 2017, 'Fibroblasts derived from oesophageal adenocarcinoma differ in DNA methylation profile from normal oesophageal fibroblasts', Scientific Reports, vol. 7, no. 1, pp. 1-9. Open access 2 3 3
2016	Smith, E, Palethorpe, HM, Ruszkiewicz, AR, Edwards, S, Leach, DA, Underwood, TJ, Need, EF & Drew, PA 2016, 'Androgen receptor and androgen-responsive gene FKBP5 are independent prognostic indicators for esophageal adenocarcinoma', Digestive Diseases and Sciences, vol. 61, no. 2, pp. 433-443. Open access 17 14 1
2015	Leach, DA, Need, EF, Toivanen, R, Trotta, AP, Palenthorpe, HM, Tamblyn, DJ, Kopsaftis, T, England, GM, Smith, E, Drew, PA, Pinnock, CB, Lee, P, Holst, J, Risbridger, GP, Chopra, S, DeFranco, DB, Taylor, RA & Buchanan, G 2015, 'Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome', Oncotarget, vol. 6, no. 18, pp. 16135-16150. Open access 68 60 1

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Flinders Medical Centre	AUSTRALIA
Flinders University	AUSTRALIA
Monash University	AUSTRALIA
New York University	UNITED STATES
QIMR Berghofer Medical Research Institute	AUSTRALIA
Queensland University of Technology	AUSTRALIA
Repatriation General Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
The Queen Elizabeth Hospital	AUSTRALIA
University of Adelaide	AUSTRALIA
University of Pittsburgh	UNITED STATES
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Southampton	UNITED KINGDOM
University of Sydney	AUSTRALIA

External engagement & recognition

Engagement/recognition	Year
JSAAE Best Poster Award The Japanese Society for Alternatives to Animal Experiments	2023
JSAAE Best Poster Award Japanese Society for Alternatives to Animal Experiments	2023
Institutional Biosafety Committee Member The Queen Elizabeth Hospital	2019
Member Australian Society for Medical Research	2019
Reviewer Cytotechnology	2019
Reviewer OncoTargets and Therapy	2019
Reviewer Cancer Management and Research	2019
Dean's Commendation for Doctoral Thesis Excellence University of Adelaide	2018
Dean's Commendation for Doctoral Thesis Excellence University of Adelaide	2018
Dean's Commendation for Doctoral Thesis Excellence University of Adelaide	2018
Institutional Biosafety Committee Member The Queen Elizabeth Hospital	2018
Member Australian Society for Medical Research	2018
Reviewer Cytotechnology	2018
Reviewer Cancer Management and Research	2018
Poster presentation with 2 minute oral award South Australian Men's Health Research Symposium	2015
Poster presentation with 3 minute oral award The Queen Elizabeth Hospital Research Day	2014
Shortlisted for Adelaide Research and Innovation Pty Ltd prize for the project with the most commercial potential Florey Postgraduate Research Conference	2014
Member Australian Society of Cytology	2012
Member South Australian Medical Scientist's Association	2012
Immunohaematology Prize CSL Bioplasma	2011
Member Australian Society of Cytology	2011
Member South Australian Medical Scientist's Association	2011
Prize for Excellence in Laboratory Medicine Terumo	2011
Member South Australian Medical Scientist's Association	2010
Member Australian Society of Cytology	2010
Member South Australian Medical Scientist's Association	2009
Member Australian Society of Cytology	2009
Member Australian Society of Cytology	2008
Member South Australian Medical Scientist's Association	2008
Member Australian Society of Cytology	2007
Member South Australian Medical Scientist's Association	2007
Member Australian Society of Cytology	2006
Member South Australian Medical Scientist's Association	2006
Prize for Clinical Chemistry - WR Odell Award Australasian Association of Clinical Biochemists	2002

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Dr Helen Palethorpe

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Journal Articles

External engagement & recognition

Collaborations

Collaborations

External engagement & recognition

JSAAE Best Poster Award

JSAAE Best Poster Award

Institutional Biosafety Committee Member

Member

Reviewer

Reviewer

Reviewer

Dean's Commendation for Doctoral Thesis Excellence

Dean's Commendation for Doctoral Thesis Excellence

Dean's Commendation for Doctoral Thesis Excellence

Institutional Biosafety Committee Member

Member

Reviewer

Reviewer

Poster presentation with 2 minute oral award

Poster presentation with 3 minute oral award

Shortlisted for Adelaide Research and Innovation Pty Ltd prize for the project with the most commercial potential

Member

Member

Immunohaematology Prize

Member

Member

Prize for Excellence in Laboratory Medicine

Member

Member

Member

Member

Member

Member

Member

Member

Member

Member

Prize for Clinical Chemistry - WR Odell Award

Gallery