Dr Michelle Perugini

Deputy Director: Commercialisation Enterprise Partnerships Unit

email Michelle.Perugini@unisa.edu.au

Alternative contact

About me

Dr. Michelle Perugini is an entrepreneur with extensive experience in healthcare and advanced AI technologies. Michelle is an avid supporter of the AI and women’s health sectors globally, and Winner of the 2021 Women in AI (WAI) Healthcare and Telstra Brilliant Women in Digital Health Awards. She has a PhD in Medicine and was a post-doctoral research fellow in Oncology for a decade. She has founded 2 global AI tech companies, the first of which was acquired by EY in 2015. Michelle was most recently the Co-Founder and CEO of Presagen, an AI healthcare company that has developed a novel Decentralized Federated AI platform that can safely train on medical data distributed all around the world, without the need to physically move... Read more

Tweets by @UniversitySA

Scopus

Research

Research focus

Biochemistry and Cell Biology
Clinical Sciences
Cardiovascular Medicine and Haematology
Oncology and Carcinogenesis
Paediatrics and Reproductive Medicine

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit Scopus

Open access indicates that an output is open access.

Journal Articles

Year	Output
2018	Beck, D, Thoms, J, Palu, C, Herold, T, Brown, A, Babic, M, Hahn, C, Perugini, M, Scott, H, Lewis, I, D'Andrea, R & Pimanda, J 2018, 'A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients', Leukemia, vol. 32, no. 2, pp. 263-272. Open access 36 35 2
2017	Sadras, T, Kok, CH, Perugini, M, Ramshaw, HS & D'Andrea, RJ 2017, 'miR-155 as a potential target of IL-3 signaling in primary AML cells', Leukemia Research, vol. 57, pp. 57-59. 7 6 1
2014	Sadras, T, Perugini, M, Kok, CH, Iarossi, DG, Heatley, SL, Brumatti, G, Samuel, MS, To, LB, Lewis, ID, Lopez, AF, Ekert, PG, Ramshaw, HS & D'Andrea, RJ 2014, 'Interleukin-3-mediated regulation of Beta-catenin in myeloid transformation and acute myeloid leukemia', Journal of Leukocyte Biology, vol. 96 no. 1, pp. 83-91. Open access 17 16
2013	Diakiw, SM, Perugini, M, Kok, CH, Engler, GA, Cummings, N, To, LB, Wei, AH, Lewis, ID, Brown, AL & D'Andrea, RJ 2013, 'Methylation of KLF5 contributes to reduced expression in acute myeloid leukaemia and is associated with poor overall survival', British Journal of Haematology, vol. 161, no. 6, pp. 884-888. Open access 17 16
2013	Hercus, TR, Dhagat, U, Kan, WL, Broughton, SE, Nero, TL, Perugini, M, Sandow, JJ, D'Andrea, RJ, Ekert, PG, Hughes, T, Parker, MW & Lopez, AF 2013, 'Signalling by the βc family of cytokines', Cytokine and Growth Factor Reviews, vol. 24, no. 3, pp. 189-201. Open access 82 75
2013	Kok, CH, Brown, AL, Perugini, M, Iarossi, DG, Lewis, ID & D'Andrea, RJ 2013, 'The preferential occurrence of FLT3-TKD mutations in inv(16) AML and impact on survival outcome: a combined analysis of 1053 core-binding factor AML patients', British Journal of Haematology, vol. 160, no. 4, pp. 557-559. Open access 9 11
2013	Perugini, M, Iarossi, D, Kok, C, Cummings, N, Diakiw, S, Brown, A, Danner, S, Bardy, P, Bik, TL, Wei, A, Lewis, I & D'Andrea, R 2013, 'GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations', Leukemia, vol. 27, pp. 1588-1592. Open access 21 20
2013	Pishas, K I, Neuhaus, SJ, Clayer, MT, Schreiber, AW, Lawrence, DM, Perugini, M, Whitfield, RJ, Farshid, G, Manavis, J, Chyrssidis, S, Mayo, BJ, Haycox, RC, Ho, K, Brown, MP, D'Andrea, RJ, Evdokiou, A, Thomas, DM, Desai, J, Callen, DF & Neilsen, PM 2013, 'Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling', Cancer Research, vol. 74, no. 3, pp. 1-11. Open access 22 22
2013	Tan, P, Wei, A, Mithraprabhu, S, Cummings, N, Liu, H, Perugini, M, Reed, K, Avery, S, Patil, S, Walker, P, Mollee, P, Grigg, A, D'Andrea, R, Dear, A & Spencer, A 2013, 'Dual epigenetic targeting with panobinostat and azacitidine in acute myeloid leukemia and high-risk myelodysplastic syndrome', Blood Cancer Journal, vol. 4, article no. e170. Open access 89 83
2012	Brown, AL, Salerno, DG, Sadras, T, Engler, GA, Kok, CH, Wilkinson, CR, Samaraweera, SE, Sadlon, TJ, Perugini, M, Lewis, ID, Gonda, TJ & D'Andrea, RJ 2012, 'The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation', Differentiation, vol. 83, no. 1, pp. 47-59. Open access 22 20
2012	Hercus, TR, Broughton, SE, Ekert, PG, Ramshaw, HS, Perugini, M, Grimbaldeston, M, Woodcock, JM, Thomas, D, Pitson, S, Hughes, T, D'Andrea, RJ, Parker, MW & Lopez, AF 2012, 'The GM-CSF receptor family: mechanism of activation and implications for disease', Growth Factors, vol. 30, no. 2, pp. 63-75. Open access 60 57
2012	Ho, YY, Penno, M, Perugini, M, Lewis, I & Hoffmann, P 2012, 'Evaluating the efficacy of subcellular fractionation of blast cells using live cell labeling and 2D DIGE', Methods in Molecular Biology, vol. 854, pp. 319-332.
2010	Lopez, AF, Hercus, TR, Ekert, P, Littler, DR, Guthridge, M, Thomas, D, Ramshaw, HS, Stomski, FC, Perugini, M, D'Andrea, RJ, Grimbaldeston, M & Parker, MW 2010, 'Molecular basis of cytokine receptor activation', IUBMB Life, vol. 62, no. 7, pp. 509-518. Open access 60 55
2010	Perugini, M, Brown, AL, Salerno, DG, Booker, GW, Stojkoski, C, Hercus, TR, Lopez, AF, Hibbs, ML, Gonda, TJ & D'Andrea, RJ 2010, 'Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit', Blood, vol. 115, no. 16, pp. 3346-3353. Open access 57 48
2010	Perugini, M, Lee, H, McRae, S & D'Andrea, RJ 2010, 'Pharmacotherapy of chronic immune thrombocytopenicpurpura (ITP) with romiplostim', Clinical Medicine Reviews in Therapeutics, vol. 2010, no. 2, pp. 129-135. Open access
2009	Perugini, M, Kok, C, Brown, A, Wilkinson, C, Salerno, D, Young, S, Lewis, I, Gonda, T & D'Andrea, R 2009, 'Repression of Gadd45a by activated FLT3 and GM-CSF receptor mutants contributes to growth, survival and blocked differentiation', Leukemia, vol. 23, no. 4, pp. 729-738. Open access 20 19
2009	Perugini, M, Varelias, A, Sadlon, T & D'Andrea, RJ 2009, 'Hematopoietic growth factor mimetics: from concept to clinic', Cytokine and Growth Factor Reviews, vol. 20, no. 1, pp. 87-94. 23 25

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Austin Hospital	AUSTRALIA
Hanson Institute	AUSTRALIA
Institute of Medical and Veterinary Science	AUSTRALIA
Ludwig Institute for Cancer Research	AUSTRALIA
Monash University	AUSTRALIA
Peter MacCallum Cancer Centre	AUSTRALIA
Princess Alexandra Hospital	AUSTRALIA
Queensland Institute of Medical Research	AUSTRALIA
Royal Adelaide Hospital	AUSTRALIA
Royal Children's Hospital	UNITED KINGDOM
Royal Melbourne Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
St. Vincent's Institute of Medical Research	AUSTRALIA
The Queen Elizabeth Hospital	AUSTRALIA
University of Adelaide	AUSTRALIA
University of Melbourne	AUSTRALIA
University of Munich	GERMANY
University of New South Wales	AUSTRALIA
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
Walter and Eliza Hall Institute of Medical Research	AUSTRALIA
Women and Children's Health Research Institute	CANADA
Women's and Children's Health Network	AUSTRALIA

more less

Dr Michelle Perugini

Alternative contact

Alternative contact details

About me

About me

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Journal Articles

External engagement & recognition

Collaborations

Collaborations

Gallery