NHMRC Early Career Research Fellow
Molecular Therapeutics Laboratory | Centre for Cancer Biology
University of South Australia & SA Pathology
HB10-34 Bradley Building | North Terrace | GPO Box 2471 Adelaide SA 5001 | Mailroom IPC: CWE-44
T: 08 8302 9067 M: 0413 392 857 E: thao.nguyen2@unisa.edu.au W: www.centreforcancerbiology.org.au
Thao is an NHMRC Early Career Research Fellow in stem cell biology, myeloid leukaemias and bone marrow microenvironment.
Thao performs fundamental, translational and clinical research that aims at targeting cancer relapse-driving stem cell populations by exploring novel therapeutic approaches to prevent cancer relapse.
About me
Thao is an NHMRC Early Career Research Fellow in stem cell biology, myeloid leukaemias and bone marrow microenvironment.
Thao performs fundamental, translational and clinical research that aims at targeting cancer relapse-driving stem cell populations by exploring novel therapeutic approaches to prevent cancer relapse.
About me
National Association of Research Fellows (NARF), of NHMRC
The International Society for Stem Cell Research
The International Society for Experimental Hematology
The Australasian Society for Stem Cell Research
The Australian Society for Medical Research
The Haematology Society of Australia and New Zealand
About me
Doctor of Philosophy University of South Australia
Bachelor of Medical and Pharmaceutical Biotechnology University of South Australia
Cancer Biology
Research
Excludes commercial-in-confidence projects.
Understanding the biological mechanisms involved in treatment free remission of chronic myeloid leukaemia, NHMRC - Early Career Fellowship, 01/01/2018 - 28/02/2022
Nanomedicine to enhance sphingosine kinase 1 targeting in acute myeloid leukaemia and improve patient outcomes
Employing humanised xenotransplantation models of acute myeloid leukaemia to predict patient outcome and direct therapy
Investigating the role of Sphingosine kinases in acute myeloid leukaemia disease initiation and progression
Ceramide-induced integrated stress response as a mechanism to overcome BCL2 inhibitor resistance in acute myeloid leukaemia
Research
Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus
Open access indicates that an output is open access.
Year | Output |
---|---|
2024 |
Open access
2
2
|
2023 |
6
5
|
2022 |
Open access
26
22
71
|
2019 |
Open access
14
14
|
2019 |
Open access
17
17
5
|
2018 |
Open access
14
13
|
2017 |
20
18
|
2016 |
20
20
|
2016 |
Open access
|
2016 |
Open access
20
20
|
2016 |
Open access
18
18
|
2015 |
Open access
29
29
1
|
2013 |
Open access
62
61
|
2010 |
24
15
|
2010 |
Open access
59
53
|
Other research degree supervision:
2020 - Honours project - Sphingosine kinases in haematopoiesis and acute myeloid leukaemia
2021 - Honours project - Liposome encapsulation of a sphingosine kinase 1 inhibitor as a potential therapy for acute myeloid leukaemia
Other publications:
Lewis AC, Tea MN, Nwosu GO, Pope VS, Nguyen TM, Wallington-Beddoe CT, Moretti PAB, Anderson D, Creek DJ, Ekert PG, Brown AL, D’Andrea R, Thomas D, Ross DM, Pitman MR, Gliddon BL, Powell JA, Pitson SM. Ceramide-induced integrated stress response as a mechanism to overcome BCL2 inhibitor resistance in acute myeloid leukaemia. Cancer Cell, 2021 (manuscript submitted)
Hayden MJ, Tabone TL, Nguyen TM, Coventry S, Keiper FJ, Fox RL, Chalmers KJ, Mather DE, Eglinton JA. An informative set of SNP markers for molecular characterisation of Australian barley germplasm. Crop Plant Sci, 2010, 61:70-83.
Sasseville M, Ritter LJ, Nguyen TM, Mottershead DG, Russell DL, Gilchrist RB. Epidermal growth factor receptor/MAPK3/1 pathway cross-talk enables growth differentiation factor 9 to signal through SMAD2/3 in mouse granulosa cells. Reproduction, Fertility and Development, 2009, 21(9): 53
Sasseville M, Nguyen TM, Ritter LJ, Russell DL, Gilchrist RB. Oocyte/GDF9 Regulation of granulosa/cumulus cell functions requires EGF receptor/MAPK3/1 signalling. Biology of Reproduction, 2009, 81(1): 107
Hayden MJ, Nguyen TM, Waterman A, McMichael GL, Chalmers KJ. Application of multiplex-ready PCR for fluorescence-based SSR genotyping in barley and wheat. Molecular Breeding, 2008, 21:271-281.
Hayden MJ, Nguyen TM, Waterman A, Chalmers KJ. Multiplex-Ready PCR: A new method for multiplexed SSR and SNP genotyping. BMC Genomics, 2008, 9:80-86.
Hayden MJ, Nguyen TM, Chalmers KJ. Development of a set of sequence tagged microsatellites (STMs) for high throughput, marker assisted selection of the stem rust resistance gene Sr2 in bread wheat. Plant Breeding, 2007, 126 (4).
External engagement & recognition
Organisation | Country |
---|---|
Beckman Research Institute | UNITED STATES |
Keio University | JAPAN |
Mayo Clinic | UNITED STATES |
SA Pathology | AUSTRALIA |
South Australian Health and Medical and Research Institute (SAHMRI) | AUSTRALIA |
South Australian Research and Development Institute (SARDI) | AUSTRALIA |
University of Adelaide | AUSTRALIA |
University of Melbourne | AUSTRALIA |
University of South Australia | AUSTRALIA |
External engagement & recognition
Engagement/recognition | Year |
---|---|
Invited Abstract ReviewerThe International Society for Stem Cell Research |
2021 |
Invited Advisory EditorStemJournal |
2021 |
Invited Peer ReviewerNature Publishing Group's Scientific Reports Journal |
2021 |
NHMRC Early Career FellowshipNational Health and Medical Research Council (NHMRC) |
2021 |
Early Career Fellowship (unable to accept)The Heart Foundation Australia |
2020 |
Invited Abstract ReviewerThe International Society for Stem Cell Research |
2020 |
Invited Advisory EditorStemJournal |
2020 |
Invited Peer ReviewerNature Publishing Group's Scientific Reports Journal |
2020 |
NHMRC Early Career FellowshipNational Health and Medical Research Council (NHMRC) |
2020 |
Early Career Fellowship (unable to accept)The Heart Foundation Australia |
2019 |
Invited Abstract ReviewerThe International Society for Stem Cell Research |
2019 |
Invited Advisory EditorStemJournal |
2019 |
Invited Peer ReviewerNature Publishing Group's Scientific Reports Journal |
2019 |
NHMRC Early Career FellowshipNational Health and Medical Research Council (NHMRC) |
2019 |
Early Career Fellowship (unable to accept)The Heart Foundation Australia |
2018 |
Early Career Researcher Travel GrantThe Australasian Society for Stem Cell Research and the National Stem Cell Foundation of Australia |
2018 |
Invited Abstract ReviewerThe International Society for Stem Cell Research |
2018 |
Invited Advisory EditorStemJournal |
2018 |
Invited Peer ReviewerNature Publishing Group's Scientific Reports Journal |
2018 |
NHMRC Early Career FellowshipNational Health and Medical Research Council (NHMRC) |
2018 |
Early Career Researcher Travel GrantAdelaide Medical School, University of Adelaide |
2017 |
Finalist of the Young Investigator AwardThe Australasian Society for Stem Cell Research and Australasian Gene and Cell Therapy Society |
2017 |
Invited Peer ReviewerNature Publishing Group's Scientific Reports Journal |
2017 |
Invited Peer ReviewerNature Publishing Group's Scientific Reports Journal |
2016 |
Best Student Oral Presentation at ASSCR/ISCT ANZ Annual MeetingThe Australasian Society for Stem Cell Research and Cellular Therapy |
2014 |
Teaching & student supervision
Teaching & student supervision
Supervisions from 2010 shown
Thesis title | Student status |
---|---|
Targeting sphingosine kinase 1 to overcome venetoclax resistance in acute myeloid leukemia | Completed |