Doctor of Philosophy The University of Adelaide
Excludes commercial-in-confidence projects.
Trafficking mechanisms governing receptor availability for signalling, NHMRC - Project Grant, 01/01/2018 - 31/12/2020
Using miR-200 to find new therapeutic targets for neuroblastoma, NHMRC - Project Grant, 01/01/2017 - 31/12/2019
miR-200 and its targets as inhibitors of neuroblastoma growth and metastasis, Channel 7 Children's Research Foundation of SA, 01/01/2015 - 31/12/2016
Regulating EGFR in breast cancer, Cancer Council SA - Beat Cancer, 01/01/2015 - 31/12/2015
Research since 2008 is shown below.
Open access indicates that an output is open access.
Pillman, KA, Phillips, CA, Roslan, S, Toubia, J, Dredge, BK, Bert, AG, Lumb, R, Neumann, DP, Li, X, Conn, SJ, Liu, D, Bracken, CP, Lawrence, DM, Schreiber, AW, Khew-Goodall, Y, Goodall, GJ & Gregory, PA and 4 other authors 2018, 'miR‐200/375 control epithelial plasticity‐associated alternative splicing by repressing the RNA‐binding protein Quaking', The EMBO journal, vol. 37, no. 13, article no. e99016, pp. 1-20.
Belle, L, Ali, N, Lonic, A, Li, X, Paltridge, JL, Roslan, S, Herrmann, D, Gehling, FK, Bert, AG, Crocker, L, Tsykin, A, Farshid, G, Goodall, GJ, Timpson, P, Daly, R & Khew-Goodall, Y 2015, 'The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking', Science Signaling, vol. 8, no. 364, article no. ra18, pp. 1-12.
15 13 11
Open access 29 31 1
Bracken, CP, Li, X, Wright, JA, Lawrence, DM, Pillman, KA, Salmanidis, M, Anderson, MA, Dredge, BK, Gregory, PA, Tsykin, A, Neilsen, C, Thomson, DW, Bert, AG, Leerberg, JM, Yap, AS, Jensen, KB, Khew-Goodall, Y & Goodall, GJ 2014, 'Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion', EMBO Journal, vol. 33, no. 18, pp. 2040-2056.
Open access 70 72 10
Attema, JL, Bert, AG, Lim, Y-Y, Kolesnikoff, N, Lawrence, DM, Pillman, KA, Smith, E, Drew, PA, Khew-Goodall, Y, Shannon, F & Goodall, GJ 2013, 'Identification of an enhancer that increases miR-200b~429 gene expression in breast cancer cells', PLoS one, vol. 8, no. 9, pp. 1-15.
Open access 11 11 4
Hauschild, N, Belle, L & Khew-Goodall, Y 2013, 'PTPN14 (protein tyrosine phosphatase, non-receptor type 14)', Atlas of genetics and cytogenetics in oncology and haematology, vol. 17, no. 7, pp. 462-466.
Lim, Y-Y, Wright, JA, Attema, JL, Gregory, PA, Bert, AG, Smith, E, Thomas, D, Lopez, AF, Drew, PA, Khew-Goodall, Y & Goodall, GJ 2013, 'Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem cell-like state', Journal of cell science, vol. 126, no. 10, pp. 2256-2266.
Open access 96 85 1
Paterson, EL, Kazenwadel, J, Bert, AG, Khew-Goodall, Y, Ruszkiewicz, A & Goodall, GJ 2013, 'Down-regulation of the miRNA-200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression', Neoplasia (United States), vol. 15, no. 2, pp. 180-191.
Open access 103 96
Gregory, PA, Bracken, CP, Smith, E, Bert, AG, Wright, JA, Roslan, S, Morris, M, Wyatt, L, Farshid, G, Lim, Y-Y, Lindeman, GJ, Shannon, MF, Drew, PA, Khew-Goodall, Y & Goodall, GJ 2011, 'An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition', Molecular biology of the cell, vol. 22, no. 10, pp. 1686-1698.
300 284 1
78 72 3
Gregory, PA, Bert, A, Paterson, E, Barry, S, Tsykin, A, Farshid, G, Vadas, M, Khew-Goodall, Y & Goodall, G 2008, 'The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1', Nature Cell Biology, vol. 10, no. 5, pp. 593-601.
2421 2241 10
Paterson, E, Prizzi, N, Gregory, PA, Bert, A, Khew-Goodall, Y & Goodall, G 2008, 'The microRNA-200 Family Regulates Epithelial to Mesenchymal Transition', The Scientific World Journal, vol. 8, pp. 901-904.
57 57 3
External engagement & recognition
|Australian National University||AUSTRALIA|
|Children's Cancer Institute Australia||AUSTRALIA|
|Garvan Institute of Medical Research||AUSTRALIA|
|La Trobe University||AUSTRALIA|
|South Australian Health and Medical Research Institute (SAHMRI)||AUSTRALIA|
|The Cancer Council South Australia||AUSTRALIA|
|The Kinghorn Cancer Centre||AUSTRALIA|
|University of Adelaide||AUSTRALIA|
|University of Canberra||AUSTRALIA|
|University of Queensland||AUSTRALIA|
|University of South Australia||AUSTRALIA|
|Walter and Eliza Hall Institute of Medical Research||AUSTRALIA|