Dr Bella Van Sebille

Program Facilitator University of South Australia Online

City West Campus (CS4-01)
tel +61 8 830 27174

email Ysabella.VanSebille@unisa.edu.au

About me

Bella is the Program Facilitator for the Bachelor of Health Sciences, the Bachelor of Nutrition and Exercise and the Diploma of Health for UniSA Online.

Bella's PhD in Medicine centred around understanding the physiological mechanisms of gastrointestinal toxicity arising from new cancer treatments (ErbB Targeted Therpaies). Her research now sits at the intersection of supportive oncology (management of cancer treatment side effects) and digital health, with a vision to harness digital health innovations to enable the provision of personalised, proactive, and efficient cancer care.

Bella is widely published, with her work cited 148% more than the world average. She is an internationally recognised expert in oncology, digital health... Read more

Tweets by @UniversitySA

Research

Research focus

Oncology and Carcinogenesis
Clinical Sciences
Medical and Health Sciences
Pharmacology and Pharmaceutical Sciences
Complementary and Alternative Medicine

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Chapters

Year	Output
2022	Wardill, HR, Van Sebille, YZ, Ali, NT & Grech, LB 2022, 'Peripheral neuropathy and cognitive impairment caused by platinum-based chemotherapy', in K Nurgali & RA Delgado (eds), Platinum-Based Chemotherapy: Clinical Uses, Efficacy and Side Effects, Nova Science Publishers, US, ch. 4, pp. 101-156.

Journal Articles

Year	Output
2025	Van Sebille, Y, Wishart, LR & Bender, JL 2025, 'Standards and practice recommendations for Telehealth in Oncology: MASCC endorsed practice recommendations developed by the American Society of Clinical Oncology', Supportive Care in Cancer, vol. 33, no. 8, article no. 743, pp. 1-4. 1 1
2024	Abdalla-Aslan, R, Bonomo, P, Keefe, D, Blijlevens, N, Van Sebille, Y & Bossi, P 22 explicit authors, 1 consortia 2024, 'Guidance on mucositis assessment from the MASCC Mucositis Study Group and ISOO: an international Delphi study', EClinicalMedicine, vol. 73, article no. 102675, pp. 1-12. Open access 7 9 10
2024	Chan, RJ, Knowles, R, Ashbury, FD, Bowen, J, Van Sebille, Y & Lustberg, M and 25 other authors and 1 consortium 2024, 'Supportive care 2030 movement: towards unifying ambitions for global excellence in supportive cancer care-an international Delphi study', EClinicalMedicine, vol. 79, pp. 1-12. Open access 3 4 8
2024	Wang, Y, Allsop, MJ, Epstein, JB, Howell, D, Rapoport, BL, Schofield, P, Van Sebille, Y, Thong, MS, Walraven, I, Ryan Wolf, J & van den Hurk, CJ 2024, 'Patient-reported symptom monitoring: using (big) data to improve supportive care at the macro-, meso-, and micro-levels', Supportive Care in Cancer, vol. 32, no.3, article no. 182, pp. 1-6. 1 1
2023	Al-Qadami, G, Bowen, J, Van Sebille, Y, Secombe, K, Dorraki, M, Verjans, J, Wardill, H & Le, H 2023, 'Baseline gut microbiota composition is associated with oral mucositis and tumour recurrence in patients with head and neck cancer: a pilot study', Supportive Care in Cancer, vol. 31, no. 1, pp. 1-14. 23 22 9
2022	Al-Qadami, G, Verma, G, Van Sebille, Y, Le, H, Hewson, I, Bateman, E, Wardill, H & Bowen, J 2022, 'Antibiotic-induced gut microbiota depletion accelerates the recovery of radiation-induced oral mucositis in rats', International Journal of Radiation Oncology Biology Physics, vol. 113, no. 4, pp. 845-858. 15 14 11
2022	Dixit, N, Van Sebille, Y, Crawford, GB, Ginex, PK, Ortega, PF & Chan, RJ 2022, 'Disparities in telehealth use: how should the supportive care community respond?', Supportive Care in Cancer, vol. 30, no. 2, pp. 1007-1010. Open access 53 45 32
2022	Gabriel, F, Marrone, R, Van Sebille, Y, Kovanovic, V & de Laat, M 2022, 'Digital education strategies around the world: practices and policies', Irish Educational Studies, vol. 41, no. 1, pp. 85-106. Open access 52 27 6
2021	Secombe, KR, Al-Qadami, GH, Subramaniam, CB, Bowen, JM, Scott, J, Van Sebille, YZ, Snelson, M, Cowan, C, Clarke, G, Gheorghe, CE, Cryan, JF & Wardill, HR 2021, 'Guidelines for reporting on animal fecal transplantation (GRAFT) studies: recommendations from a systematic review of murine transplantation protocols', Gut Microbes, vol. 13, no. 1, article no. 1979878, pp. 1-14. Open access 61 57 79
2020	Secombe, KR, Van Sebille, YZ, Mayo, BJ, Coller, JK, Gibson, RJ & Bowen, JM 2020, 'Diarrhea induced by small molecule tyrosine kinase inhibitors compared with chemotherapy: potential role of the microbiome', Integrative Cancer Therapies, vol. 19, pp. 1-12. Open access 55 51 13
2020	Wardill, H, Sonis, S, Blijlevens, N, Van Sebille, Y, Ciorba, M, Loeffen, E, Cheng, K, Bossi, P, Porcello, L, Castillo, D, Elad, S & Bowen, J 2020, 'Prediction of mucositis risk secondary to cancer therapy: a systematic review of current evidence and call to action', Supportive Care in Cancer, online, pp. 1-15. 66 58 17
2019	Al-Qadami, G, Van Sebille, Y, Le, H & Bowen, J 2019, 'Gut microbiota: implications for radiotherapy response and radiotherapy-induced mucositis', Expert Review of Gastroenterology and Hepatology, vol. 13, no. 5, pp. 485-496. 66 59 4
2019	Bowen, J, Al-Dasooqi, N, Bossi, P, Wardill, H, Van Sebille, Y, Al-Azri, A, Bateman, E, Correa, M, Raber-Durlacher, J, Kandwal, A, Mayo, B, Nair, R, Stringer, A, ten Bohmer, K, Thorpe, D, Lalla, R, Sonis, S, Cheng, K & Elad, S 2019, 'The pathogenesis of mucositis: updated perspectives and emerging targets', Supportive Care in Cancer, vol. 27, no. 10, pp. 4023-4033. 139 119 9
2019	Bowen, JM, Gibson, RJ, Coller, JK, Blijlevens, N, Bossi, P, Al-Dasooqi, N, Bateman, EH, Chiang, K, de Mooij, C, Mayo, B, Stringer, AM, Tissing, W, Wardill, HR, van Sebille, YZ, Ranna, V, Vaddi, A, Keefe, DM, Lalla, R V, Cheng, KKF & Elad, S 2019, 'Systematic review of agents for the management of cancer treatment-related gastrointestinal mucositis and clinical practice guidelines', Supportive Care in Cancer, vol. 27, no. 10, pp. 4011-4022. Open access 67 53 9
2019	Van Sebille, YZ, Gibson, RJ, Wardill, HR, Carney, TJ & Bowen, JM 2019, 'Use of zebrafish to model chemotherapy and targeted therapy gastrointestinal toxicity', Experimental Biology and Medicine, vol. 244, pp. 1178-1185. Open access 18 17 5
2018	Gibson, RJ, van Sebille, YZ, Wardill, HR, Wignall, A, Shirren, J, Ball, IA, Williams, N, Wanner, K & Bowen, JM 2018, 'Selective MMP inhibition, using AZD3342, to reduce gastrointestinal toxicity and enhance chemoefficacy in a rat model', ChemoTherapy: International Journal of Experimental and Clinical ChemoTherapy, vol. 63, no. 5, pp 284-292. Open access 5 5 1
2018	Van Sebille, YZ, Gibson, RJ, Wardill, HR, Ball, IA, Keefe, DM & Bowen, JM 2018, 'Dacomitinib-induced diarrhea: Targeting chloride secretion with crofelemer', International Journal of Cancer, vol. 142, no. 2, pp. 369-380. Open access 15 14
2018	Wardill, HR, Van Sebille, YZ, Ciorba, MA & Bowen, JM 2018, 'Prophylactic probiotics for cancer therapy-induced diarrhoea: a meta-analysis', Current Opinion in Supportive and Palliative Care, vol. 12, no. 2, pp. 187-197. 54 52 4
2017	Coller, JK, Bowen, JM, Ball, IA, Wardill, HR, Van Sebille, YZ, Stansborough, RL, Lightwala, Z, Wignall, A, Shirren, J, Secombe, K & Gibson, RJ 2017, 'Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report', Cancer Chemotherapy and Pharmacology, vol. 79, no. 2, pp. 431-434. 9 8
2017	Van Sebille, YZ, Gibson, RJ, Wardill, HR, Secombe, KR, Ball, IA, Keefe, DM, Finnie, JW & Bowen, JM 2017, 'Dacomitinib-induced diarrhoea is associated with altered gastrointestinal permeability and disruption in ileal histology in rats', International Journal of Cancer, vol. 140, no. 12, pp. 2820-2829. Open access 31 27 4
2016	Van Sebille, YZ, Gibson, RJ, Wardill, HR & Bowen, JM 2016, 'Gastrointestinal toxicities of first and second-generation small molecule human epidermal growth factor receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer', Current Opinion in Supportive and Palliative Care, vol. 10, no. 2, pp. 152-156. 7 6 1
2016	Wardill, HR, Bowen, JM, Van Sebille, YZ, Secombe, KR, Coller, JK, Ball, IA, Logan, RM & Gibson, RJ 2016, 'TLR4-dependent claudin-1 internalization and secretagogue-mediated chloride secretion regulate irinotecan-induced diarrhea', Molecular Cancer Therapeutics, vol. 15, no. 11, pp. 2767-2779. Open access 44 39
2016	Wardill, HR, Gibson, RJ, Van Sebille, YZ, Secombe, KR, Coller, JK, White, IA, Manavis, J, Hutchinson, MR, Staikopoulos, V, Logan, RM & Bowen, JM 2016, 'Irinotecan-Induced gastrointestinal dysfunction and pain are mediated by common TLR4-dependent mechanisms', Molecular Cancer Therapeutics, vol. 15, no. 6, pp. 1376-1386. Open access 120 111 2
2016	Wardill, HR, Gibson, RJ, Van Sebille, YZ, Secombe, KR, Logan, RM & Bowen, JM 2016, 'A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options', Experimental Biology and Medicine, vol. 241, no. 13, pp. 1386-1394. Open access 8 7
2016	Wardill, HR, Logan, RM, Bowen, JM, Van Sebille, YZ & Gibson, RJ 2016, 'Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer', Supportive Care in Cancer, vol. 24, no. 4, pp. 1779-1788. Open access 17 17
2016	Wardill, HR, Mander, KA, Van Sebille, YZ, Gibson, RJ, Logan, RM, Bowen, JM & Sonis, ST 2016, 'Cytokine-mediated blood brain barrier disruption as a conduit for cancer/chemotherapy-associated neurotoxicity and cognitive dysfunction', International Journal of Cancer, vol. 139, no. 12, pp. 2635-2645. 133 115 1
2015	Van Sebille, YZ, Gibson, RJ, Wardill, HR & Bowen, JM 2015, 'ErbB small molecule tyrosine kinase inhibitor (TKI) induced diarrhoea: chloride secretion as a mechanistic hypothesis', Cancer Treatment Reviews, vol. 41, no. 7, pp. 646-652. 56 52 6
2015	Van Sebille, YZ, Stansborough, R, Wardill, HR, Bateman, E, Gibson, RJ & Keefe, DM 2015, 'Management of mucositis during chemotherapy: from pathophysiology to pragmatic therapeutics', Current Oncology Reports, vol. 17, no. 11, article no. 50, pp. 1-8. 71 60 1
2015	Wardill, HR, Van Sebille, YZ, Mander, KA, Gibson, RJ, Logan, RM, Bowen, JM & Sonis, ST 2015, 'Toll-like receptor 4 signaling: a common biological mechanism of regimen-related toxicities: an emerging hypothesis for neuropathy and gastrointestinal toxicity', Cancer Treatment Reviews, vol. 41, no. 2, pp. 122-128. 34 32 14

Conferences

Year	Output
2018	Van Sebille, Y, Joksimovic, S, Kovanovic, V, Stansborough, R & Dawson, S 2018, 'Extending video interactions to support self-regulated learning in an online course', 35th International Conference of Innovation, Practice and Research in the use of Educational Technologies in Tertiary Education, ASCILITE 2018, ASCILITE, pp. 262-272. Open access 4

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Agency for Science, Technology and Research (A*STAR)	SINGAPORE
Al Nahdha Hospital	OMAN
Al-Yarmouk College	SUDAN
Azienda Ospedaliero-Universitaria Careggi	ITALY
Brigham and Women's Hospital	UNITED STATES
Cancer Australia	AUSTRALIA
City of Hope Comprehensive Cancer Center - Duarte	UNITED STATES
Dana-Farber Cancer Institute	UNITED STATES
Eastman Institute for Oral Health	UNITED STATES
Flinders University	AUSTRALIA
Free University of Amsterdam	NETHERLANDS
German Cancer Research Center	GERMANY
Griffith University	AUSTRALIA
Humanitas University	ITALY
Institut Català d’Oncologia	SPAIN
Medical Oncology Centre of Rosebank	SOUTH AFRICA
Monash University	AUSTRALIA
Mount Sinai Hospital	UNITED STATES
National University of Singapore	SINGAPORE
Netherlands Comprehensive Cancer Organisation	NETHERLANDS
Northern Adelaide Local Health Network	AUSTRALIA
Oncology Nursing Society	UNITED STATES
Princess Margaret Cancer Centre	CANADA
Radboud University Medical Centre	NETHERLANDS
Radboud University Nijmegen Medical Centre	NETHERLANDS
Rambam Health Care Campus	ISRAEL
Royal Adelaide Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
Smilow Cancer Hospital	UNITED STATES
St Vincent's Hospital Melbourne	AUSTRALIA
Swami Rama Himalayn University	INDIA
The Alfred Hospital	AUSTRALIA
University College Cork	IRELAND
University of Adelaide	AUSTRALIA
University of Brescia	ITALY
University of Calgary	CANADA
University of California	UNITED STATES
University of Campinas	BRAZIL
University of Connecticut	UNITED STATES
University of Groningen	NETHERLANDS
University of Leeds	UNITED KINGDOM
University of Melbourne	AUSTRALIA
University of Pittsburgh	UNITED STATES
University of Rochester	UNITED STATES
University of Rochester Medical Center	UNITED STATES
University of South Australia	AUSTRALIA
University of Sydney	AUSTRALIA
University of Toronto	CANADA
Washington University in St Louis	UNITED STATES

External engagement & recognition

Engagement/recognition	Year
AIDH Member Australian Institute of Digital Health	2025
Chair of MASCC Digital Health Study Group The Multinational Association of Supportive Care in Cancer	2025
'Digital Health for Informed Decision Making in Supportive Care in Cance' The MASCC Annual Scientific Meeting, Seattle, USA The Multinational Association of Supportive Care in Cancer	2025
Invited consultation on the Digital Health Network’s Horizon policy “Digital Transition and Digital Resilience in Oncology" European Cancer Organisation (ECO)	2025
MASCC Member The Multinational Association of Supportive Care in Cancer	2025
‘Sharing is caring: importance of clinical and PROM data repositories and data sharing in advancing supportive care' Dutch Association for Supportive Care in Cancer ASM, Utrecht, The Netherlands The Dutch Association of Supportive Care in Cancer	2024
Chair of MASCC Digital Health Study Group The Multinational Association of Supportive Care in Cancer	2024
Invited consultation on the Digital Health Network’s Horizon policy “Digital Transition and Digital Resilience in Oncology" European Cancer Organisation (ECO)	2024
MASCC Member The Multinational Association of Supportive Care in Cancer	2024
Chair of MASCC Digital Health Study Group The Multinational Association of Supportive Care in Cancer	2023
Invited consultation on the Digital Health Network’s Horizon policy “Digital Transition and Digital Resilience in Oncology" European Cancer Organisation (ECO)	2023
Invited Submission to the European Cancer Organisation on the Digital Health Network’s Horizon policy “Digital Transition and Digital Resilience in Oncology” European Cancer Organisation	2023
MASCC Member The Multinational Association of Supportive Care in Cancer	2023
'Mucositis assessment tools: the importance of consistency in the digital world', MASCC Annual Scientific Meeting, Nara, Japan. The Multinational Association of Supportive Care in Cancer	2023
'Cancer Associated Thrombosis: Digital Health Interventions to address disparities in care', MASCC Annual Scientific Meeting, Toronto, Canada The Multinational Association of Supportive Care in Cancer	2022
Chair of MASCC Digital Health Study Group The Multinational Association of Supportive Care in Cancer	2022
COSA Member Clinical Oncology Society of Australia (COSA)	2022
MASCC Member The Multinational Association of Supportive Care in Cancer	2022
Chair of MASCC Digital Health Study Group The Multinational Association of Supportive Care in Cancer	2021
COSA Member Clinical Oncology Society of Australia (COSA)	2021
'Digital Health in Supportive Cancer Care', MASCC Annual Scientific Meeting, Virtual The Multinational Association of Supportive Care in Cancer	2021
MASCC Member The Multinational Association of Supportive Care in Cancer	2021
Chair of MASCC Digital Health Study Group The Multinational Association of Supportive Care in Cancer	2020
COSA Member Clinical Oncology Society of Australia (COSA)	2020
MASCC Member The Multinational Association of Supportive Care in Cancer	2020
COSA Member Clinical Oncology Society of Australia (COSA)	2019
MASCC Member The Multinational Association of Supportive Care in Cancer	2019
Prime Innovation Program, SA winner Commonwealth Scientific and Industrial Research Organisation (CSIRO)	2019
Ambassador Multinational Association of Supportive Care in Cancer (MASCC)	2018
COSA Member Clinical Oncology Society of Australia (COSA)	2018
Information and Communication Committee Multinational Association of Supportive Care in Cancer (MASCC)	2018
Invited Presenter STEMable	2018
Invited Presenter AsiaAus Leader Opt In, Stand Out event	2018
Invited Presenter The University Medical Centre, Groningen, The Netherlands	2018
MASCC Member The Multinational Association of Supportive Care in Cancer	2018
Sessions Chair Multinational Association of Supportive Care in Cancer	2018
Ad-Hoc Reviewer Pathophysiology	2017
Ad-Hoc Reviewer Annals of Hematology	2017
Ad-Hoc Reviewer British Medical Journal	2017
Channel 9 Young Achiever Awards: Science and Technology Award Channel 9	2017
Co-founder and committee member for working group to develop The University of Adelaide Student-Led Teaching Award The University of Adelaide	2017
COSA Member Clinical Oncology Society of Australia (COSA)	2017
Finalist, Channel 9 Young Achiever Award in Service to the Community category Channel 9	2017
Invited Presenter Adelaide Medical School Honours cohort, University of Adelaide	2017
Invited presenter: Cancer Treatment Toxicities A-STAR (Agency for Science, Technology and Research), Singapore	2017
MASCC Member The Multinational Association of Supportive Care in Cancer	2017
Semi-finalist, Channel 9 Young Achiever Award in Create Change category Channel 9	2017
Treasurer Australian Society for Medical Research (ASMR)	2017
COSA Member Clinical Oncology Society of Australia (COSA)	2016
Invited presenter: Characterisation of dacomitinib-induced diarrhoea targeting chloride secretion Pfizer pharmaceuticals	2016
Invited presenter: Comparison of chemotherapy and targeted therapy induced diarrhoea Basil Hetzel Research Seminar	2016
John Barker Prize in Cancer Research University of Adelaide	2016
MASCC Member The Multinational Association of Supportive Care in Cancer	2016
Northern Communities Health Foundation Prize Northern Communities Health Foundation	2016
Radio Interview: As if Cancer Was not Shitty Enough Australian Broadcasting Corporation 891	2016
Florey Medical Research Foundation Project Grant in Cancer Research University of Adelaide	2015
MASCC Member The Multinational Association of Supportive Care in Cancer	2015
Invited presenter: Cancer therapy-induced gut toxicity: recent advances in pathobiology Monash University	2014
Invited presenter: Cancer therapy-induced gut toxicity: recent advances in pathobiology Peter MacCallum Cancer Centre	2014

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Dr Bella Van Sebille

About me

About me

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Chapters

Journal Articles

Conferences

External engagement & recognition

Collaborations

Collaborations

External engagement & recognition

AIDH Member

Chair of MASCC Digital Health Study Group

'Digital Health for Informed Decision Making in Supportive Care in Cance' The MASCC Annual Scientific Meeting, Seattle, USA

Invited consultation on the Digital Health Network’s Horizon policy “Digital Transition and Digital Resilience in Oncology"

MASCC Member

‘Sharing is caring: importance of clinical and PROM data repositories and data sharing in advancing supportive care' Dutch Association for Supportive Care in Cancer ASM, Utrecht, The Netherlands

Chair of MASCC Digital Health Study Group

Invited consultation on the Digital Health Network’s Horizon policy “Digital Transition and Digital Resilience in Oncology"

MASCC Member

Chair of MASCC Digital Health Study Group

Invited consultation on the Digital Health Network’s Horizon policy “Digital Transition and Digital Resilience in Oncology"

Invited Submission to the European Cancer Organisation on the Digital Health Network’s Horizon policy “Digital Transition and Digital Resilience in Oncology”

MASCC Member

'Mucositis assessment tools: the importance of consistency in the digital world', MASCC Annual Scientific Meeting, Nara, Japan.

'Cancer Associated Thrombosis: Digital Health Interventions to address disparities in care', MASCC Annual Scientific Meeting, Toronto, Canada

Chair of MASCC Digital Health Study Group

COSA Member

MASCC Member

Chair of MASCC Digital Health Study Group

COSA Member

'Digital Health in Supportive Cancer Care', MASCC Annual Scientific Meeting, Virtual

MASCC Member

Chair of MASCC Digital Health Study Group

COSA Member

MASCC Member

COSA Member

MASCC Member

Prime Innovation Program, SA winner

Ambassador

COSA Member

Information and Communication Committee

Invited Presenter

Invited Presenter

Invited Presenter

MASCC Member

Sessions Chair

Ad-Hoc Reviewer

Ad-Hoc Reviewer

Ad-Hoc Reviewer

Channel 9 Young Achiever Awards: Science and Technology Award

Co-founder and committee member for working group to develop The University of Adelaide Student-Led Teaching Award

COSA Member

Finalist, Channel 9 Young Achiever Award in Service to the Community category

Invited Presenter

Invited presenter: Cancer Treatment Toxicities

MASCC Member

Semi-finalist, Channel 9 Young Achiever Award in Create Change category

Treasurer

COSA Member

Invited presenter: Characterisation of dacomitinib-induced diarrhoea targeting chloride secretion

Invited presenter: Comparison of chemotherapy and targeted therapy induced diarrhoea

John Barker Prize in Cancer Research

MASCC Member

Northern Communities Health Foundation Prize

Radio Interview: As if Cancer Was not Shitty Enough

Florey Medical Research Foundation Project Grant in Cancer Research

MASCC Member

Invited presenter: Cancer therapy-induced gut toxicity: recent advances in pathobiology

Invited presenter: Cancer therapy-induced gut toxicity: recent advances in pathobiology

Teaching & student supervision

Courses and programs

Courses I teach

'Mucositis assessment tools: the importance of consistency in the digital world', MASCC Annual Scientific Meeting, Nara, Japan.