Dr Claire Homan

Research Fellow Centre for Cancer Biology

email Claire.Homan@unisa.edu.au

Research Degree Supervisor

Research

Research focus

Clinical Sciences
Biological Sciences
Medical and Health Sciences
Neurosciences
Biochemistry and Cell Biology

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID, ResearcherID or Scopus

Open access indicates that an output is open access.

Chapters

Year	Output
2016	Pham, D, Tan, C, Homan, C, Jolly, L & Gecz, J 2016, 'Protocadherin Mutations in Neurodevelopmental Disorders', in C Sala & C Verpelli (eds), Neuronal and synaptic dysfunction in autism spectrum disorder and intellectual disability, Elsevier, UK, ch. 14, pp. 221-231. 2

Journal Articles

Year	Output
2024	Zerella, JR, Homan, CC, Arts, P, Lin, X, Spinelli, SJ, Venugopal, P, Babic, M, Brautigan, PJ, Arriola-Martinez, L, Parker, WT, Branford, S, Ross, DM, Brown, AL, Scott, HS & Hahn, CN 37 other authors and 1 consortium 2024, 'Germ line ERG haploinsufficiency defines a new syndrome with cytopenia and hematological malignancy predisposition', Blood, online, pp. 1-42. Open access
2023	Homan, C, Scott, H & Brown, A 2023, 'Hereditary platelet disorders associated with germline variants in RUNX1, ETV6 and ANKRD26', Blood, vol. 141, no.13, pp. 1533-1543. Open access 20 22 5
2023	Homan, CC, Drazer, MW, Yu, K, Lawrence, DM, Feng, J, Arriola-Martinez, LA, Ha, TT, Venugopal, P, Arts, P, King-Smith, S, Cheah, JJC, Armstrong, M, Wang, P, Babic, M, Scott, HS & Brown, AL and 49 other authors 2023, 'Somatic mutational landscape of hereditary hematopoietic malignancies caused by germ line RUNX1, GATA2, and DDX41 variants', Blood Advances, vol. 7, no. 20, pp. 6092-6107. Open access 13 3
2023	Zerella, JR, Homan, CC, Arts, P, Brown, AL, Scott, HS & Hahn, CN 2023, 'Transcription factor genetics and biology in predisposition to bone marrow failure and hematological malignancy', Frontiers in Oncology, vol. 13, article no. 1183318. Open access 2 1
2022	Drazer, MW, Homan, CC, Yu, K, de Andrade Silva, M, Feng, J, King-Smith, SL, Lawrence, DM, Schreiber, AW, Hahn, CN, Scott, HS, Brown, AL & Godley, LA and 10 other authors & 1 consortia 2022, 'Clonal hematopoiesis in patients with ANKRD26 or ETV6 germline mutations.', Blood Advances, vol. 6, no. 15, pp. 4357-4359. Open access 15 15 1
2021	Homan, CC, Venugopal, P, Arts, P, Shahrin, NH, Feurstein, S, Rawlings, L, Lawrence, DM, Andrews, J, King-Smith, SL, Harvey, NL, Brown, AL, Scott, HS & Hahn, CN 2021, 'GATA2 deficiency syndrome: a decade of discovery', Human Mutation, vol. 42, no. 11, pp. 1399-1421. Open access 33 31 9
2021	Mincheva-Tasheva, S, Nieto Guil, AF, Homan, CC, Gecz, J & Thomas, PQ 2021, 'Disrupted excitatory synaptic contacts and altered neuronal network activity underpins the neurological phenotype in PCDH19-Clustering Epilepsy (PCDH19-CE)', Molecular Neurobiology, vol. 58, no. 5, pp. 2005-2018. 18 17
2020	Brown, AL, Arts, P, Babic, M, Dobbins, J, Feng, J, Ha, T, Homan, CC, King-Smith, SL, Li, X-C, Brautigan, P, Butcher, C, D'Andrea, RJ, Hahn, CN & Scott, HS and 46 other authors 2020, 'RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML', Blood Advances, vol. 4, no. 6, pp. pp. 1131-1144. Open access 99 94 5
2019	Jackson, MR, Loring, KE, Homan, CC, Thai, MH, Määttänen, L, Arvio, M, Jarvela, I, Shaw, M, Gardner, A, Gecz, J & Shoubridge, C 2019, 'Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in females', Life Science Alliance, vol. 2, no. 4, pp. 1-18. Open access 16 15 3
2018	Homan, CC, Pederson, S, To, T-H, Tan, C, Piltz, S, Corbett, MA, Wolvetang, E, Thomas, PQ, Jolly, LA & Gecz, J 2018, 'PCDH19 regulation of neural progenitor cell differentiation suggests asynchrony of neurogenesis as a mechanism contributing to PCDH19 Girls Clustering Epilepsy', Neurobiology of Disease, vol. 116, pp. 106-119. Open access 43 36
2018	Jolly, LA, Sun, Y, Carroll, R, Homan, CC & Gecz, J 2018, 'Robust imaging and gene delivery to study human lymphoblastoid cell lines', Journal of Human Genetics, vol. 63, no. 9, pp. 945-955. 2 2 1
2018	Kumar, R, Gardner, A, Homan, CC, Douglas, E & Gecz, J and 26 other authors and 1 consortium 2018, 'Severe neurocognitive and growth disorders due to variation in THOC2, an essential component of nuclear mRNA export machinery', Human Mutation, vol. 39, no. 8, pp. 1126-1138. Open access 17 18 1
2017	Pham, DH, Tan, CC, Homan, CC, Kolc, KL, Corbett, MA, McAninch, D, Fox, AH, Thomas, PQ, Kumar, R & Gecz, J 2017, 'Protocadherin 19 (PCDH19) interacts with paraspeckle protein NONO to co-regulate gene expression with estrogen receptor alpha (ERα)', Human Molecular Genetics. Open access 26 24 3
2016	Pederick, DT, Homan, CC, Jaehne, EJ, Piltz, SG, Haines, BP, Baune, BT, Jolly, LA, Hughes, JN, Gecz, J & Thomas, PQ 2016, 'Pcdh19 Loss-of-Function Increases Neuronal Migration In Vitro but is Dispensable for Brain Development in Mice', Scientific Reports, vol. 6, article no. 26765, pp. 1-10. Open access 50 45 6
2014	Hamon, R, Homan, CC, Tran, HB, Mukaro, VR, Lester, SE, Roscioli, E, Bosco, MD, Murgia, CM, Ackland, ML, Jersmann, HP, Lang, C, Zalewski, PD & Hodge, SJ 2014, 'Zinc and zinc transporters in macrophages and their roles in efferocytosis in COPD', PLoS One, vol. 9, no. 10, article no. e110056, pp. 1-9. Open access 51 51 2
2014	Homan, CC, Kumar, R, Nguyen, LS, Haan, E, Raymond, FL, Abidi, F, Raynaud, M, Schwartz, CE, Wood, SA, Gecz, J & Jolly, LA 2014, 'Mutations in USP9X are associated with x-linked intellectual disability and disrupt neuronal cell migration and growth', American Journal of Human Genetics, vol. 94, no. 3, pp. 470-478. Open access 109 106 136
2013	Jolly, LA, Homan, CC, Jacob, R, Barry, S & Gecz, J 2013, 'The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth', Human Molecular Genetics, vol. 22, no. 23, pp. 4673-4687. Open access 98 91

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
CREA - Research Center for Food and Nutrition	ITALY
Deakin University	AUSTRALIA
Federal University of Alagoas	BRAZIL
Greenwood Genetics Center	UNITED STATES
Griffith University	AUSTRALIA
Hudson Institute of Medical Research	AUSTRALIA
National Human Genome Research Institute	UNITED STATES
National Institutes of Health	UNITED STATES
Regional University Hospital of Tours	FRANCE
Royal Adelaide Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
The Queen Elizabeth Hospital	AUSTRALIA
Turku University Hospital	FINLAND
University of Adelaide	AUSTRALIA
University of Cambridge	UNITED KINGDOM
University of Chicago	UNITED STATES
University of Helsinki	FINLAND
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Western Australia	AUSTRALIA
Women's and Children's Hospital	AUSTRALIA

External engagement & recognition

Engagement/recognition	Year
Board Member HGSA SA Branch committee member	2022
Chair International RUNX1 Inherited Hematologic Malignancies Consortium Working Group	2022
Invited Speaker Human Genetics Society of Australasia (HGSA) SA Branch Seminar	2022
ASM Travel Award Human Genetics Society of Australasia (HGSA) SA Branch	2021
Chair International RUNX1 Inherited Hematologic Malignancies Consortium Working Group	2021
Founding Committee Member BLiSS Science and Innovation Inc	2021
Invited Speaker 2nd National Symposium on BMFS, Maddie Riewoldt's Vision	2021
Member of an advisory board ClinGen Myeloid Malignancy Variant Curation Expert Panel	2021
Program Chair BLiSS Science and Innovation Inc, Adelaide Chapter	2021
Founding Committee Member BLiSS Science and Innovation Inc	2020
Founding Committee Member BLiSS Science and Innovation Inc	2019
Organiser 1st Annual Adelaide Stem Cell Network meeting -collaborators day	2017
Best Oral Presentation Award 2nd Annual Collaborative Conference of Cell Reprogramming Australia - The Making of Reprogramming, Melbourne	2014
Education Award National Stem Cell Foundation of Australia Conference	2013

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
Examining the role of the pathogenic bone marrow microenvironment and hematopoietic stem cell stress in the development of leukaemia in blood cancer predisposition	Current

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Dr Claire Homan

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Chapters

Journal Articles

External engagement & recognition

Collaborations

Collaborations

External engagement & recognition

Board Member

Chair

Invited Speaker

ASM Travel Award

Chair

Founding Committee Member

Invited Speaker

Member of an advisory board

Program Chair

Founding Committee Member

Founding Committee Member

Organiser

Best Oral Presentation Award

Education Award

Teaching & student supervision

Courses and programs

Research degree supervision

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