Professor Claudine Bonder

Research Professor Centre for Cancer Biology

City West Campus (HB10-12)
tel +61 8 830 27833

mob +61 424371215
email Claudine.Bonder@unisa.edu.au

Available for media comment
Research Degree Supervisor

About me

Professor Claudine Bonder OAM is an expert in vascular biology with 25 years experience having trained both in Australia and overseas. She currently heads the Vascular Biology and Cell Trafficking Laboratory at the Centre for Cancer Biology in Adelaide. During her career, Claudine has been awarded the prestigious Early Career Research Award from the Australian Academy of Sciences in 2005, a SA Young Tall Poppy in 2010, was an ASMR Leading Light finalist in 2013, won the Women in Innovation (emerging innovator) in 2016 and in 2025 was awarded a Medal of the Order of Australia.

Research Program Overview:

Blood vessels form an extensive network that transports cells, oxygen and nutrients throughout all tissues and organs. Blood vessels ... Read more

Centre for Cancer Biology

Making breakthrough discoveries in the fundamental causes of cancer, and translating these into prevention and treatment.

Tweets by @UniversitySA

Research

Research focus

Biochemistry and Cell Biology
Clinical Sciences
Biological Sciences
Medical and Health Sciences
Oncology and Carcinogenesis

Highlights

Our expertise in blood vessels, and the endothelial cells which form their inner lining, allows us to critically interrogate diseases such as cancer, cardiovascular disease and diabetes. Our ultimate aim is to understand the fundamental biology of the blood vasculature so that new treatment opportunities for the most debilitating and deadly diseases can be produced to save thousands of lives every year, worldwide.

Research

Projects

Excludes commercial-in-confidence projects.

Advancing a new targeted antibody to combat pancreatic cancer, PanKind Australia - New Treatment Grant, 16/12/2024 - 31/12/2026
CRC-P: Internal Testing and assessment of CAR-T cells using in vitro methods and in vivo animal tumour models, UniSA-Internal, 29/02/2020 - 30/06/2026
Advancing a novel early detection biomarker for pancreatic cancer, Tour de Cure Ltd, 01/03/2022 - 31/12/2025
Enhancing Skin Cancer Diagnosis and Treatment through biomarker discovery, Tour de Cure Ltd, 01/01/2025 - 31/12/2025
Exploiting blood vessels as conduits for the entry of therapeutic CAR-T cells into brain tumours, Neurosurgical Research Foundation, 02/10/2023 - 31/10/2025
MTA_ATCC - Spatial proteomics to define tumour microenvironments , Unknown, 11/10/2022 - 11/10/2024
Desmoglein-2; an unsuspected regulator of melanoma, NHMRC - Project Grant, 01/01/2019 - 31/12/2022
Investigating a novel adhesion molecule in pancreatic cancer, PanKind Australia - New Treatment Grant, 01/01/2022 - 31/10/2022
Engineered cell and exosome therapy for pulmonary vascular disease, NHMRC - Project Grant, 01/01/2018 - 31/12/2021
Targeting the IL-3/IL-3 receptor axis to prevent breast cancer progression., CA-Priority-driven Collaborative Cancer Research Scheme, 01/05/2016 - 31/03/2020
Desmoglein-2: A novel lifeline to treat diabetes, NHMRC - Project Grant, 01/01/2016 - 31/12/2019
Validation of a novel therapeutic target in multiple myeloma, Royal Adelaide Hospital, 01/01/2016 - 31/03/2017
Checkpoint blockade immunotherapy in melanoma: getting tumour-killing T cells to their site of action, Royal Adelaide Hospital, 01/01/2016 - 31/03/2017

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Highlights

Year	Output
2025	Thompson, EJ, Dorward, EL, Jurrius, K, Nataren, N, Tondl, M, Myo Min, KK, Cockshell, MP, Fouladzadeh, A, Toubia, J, Denichilo, M, Merino, D & Bonder, CS 2025, 'Inhibitor of DNA binding-1 is a key regulator of cancer cell vasculogenic mimicry', Molecular Oncology, online, pp. 1-20. Open access
2024	Moore, E, Robson, AJ, Crisp, AR, Cockshell, MP, Burzava, AL, Ganesan, R, Robinson, N, Tondl, M, Griesser, HJ & Bonder, CS and 16 other authors 2024, 'Study of the structure of hyperbranched polyglycerol coatings and their antibiofouling and antithrombotic applications', Advanced Healthcare Materials, vol. 13, no.26, pp. 1-23. Open access 2 1 2
2023	Bandara, V, Foeng, J, Gundsambuu, B, Norton, TS, Mills, SJ, Tan, LY, Thompson, EJ, Coombs, J, Cowin, AJ, Bonder, CS & Barry, SC and 15 other authors 2023, 'Pre-clinical validation of a pan-cancer CAR-T cell immunotherapy targeting nfP2X7', Nature Communications, vol. 14, no. 1, article no. 5546, pp. 1-17. Open access 13 15 6
2023	Myo Min, KK, Ffrench, CB, McClure, BJ, Ortiz, M, Dorward, EL, Samuel, MS, Ebert, LM, Mahoney, Mỹ & Bonder, CS 2023, 'Desmoglein-2 as a cancer modulator: friend or foe?', Frontiers in Oncology, vol. 13, article no. 1327478 , pp. 1-15. Open access 4 5 2
2022	Ebert, LM, Vandyke, K, Johan, MZ, DeNichilo, M, Tan, LY, Myo Min, KK, Weimann, BM, Ebert, BW, Pitson, SM, Zannettino, AC, Wallington-Beddoe, CT & Bonder, CS 2022, 'Desmoglein-2 expression is an independent predictor of poor prognosis patients with multiple myeloma', Molecular Oncology, vol. 16, no. 6, pp. 1221-1240. Open access 11 12 13

Journal Articles

Year	Output
2025	Thompson, EJ, Dorward, EL, Jurrius, K, Nataren, N, Tondl, M, Myo Min, KK, Cockshell, MP, Fouladzadeh, A, Toubia, J, Denichilo, M, Merino, D & Bonder, CS 2025, 'Inhibitor of DNA binding-1 is a key regulator of cancer cell vasculogenic mimicry', Molecular Oncology, online, pp. 1-20. Open access
2024	Moore, E, Robson, AJ, Crisp, AR, Cockshell, MP, Burzava, AL, Ganesan, R, Robinson, N, Tondl, M, Griesser, HJ & Bonder, CS and 16 other authors 2024, 'Study of the structure of hyperbranched polyglycerol coatings and their antibiofouling and antithrombotic applications', Advanced Healthcare Materials, vol. 13, no.26, pp. 1-23. Open access 2 1 2
2024	Thompson, EJ, Escarbe, S, Tvorogov, D, Farshid, G, Gregory, PA, Khew-Goodall, Y, Madden, S, Ingman, W V, Lindeman, GJ, Lim, E, Lopez, AF & Bonder, CS 2024, 'Interleukin-3 production by basal-like breast cancer cells is associated with poor prognosis', Growth Factors, vol. 42, no. 2, pp. 49–61. Open access 1
2024	Williamson, AE, Liyanage, S, Hassanshahi, M, Dona, MS, Kazenwadel, J, Harvey, NL, Bonder, CS & Psaltis, PJ and 19 other authors 2024, 'Discovery of an embryonically derived bipotent population of endothelial-macrophage progenitor cells in postnatal aorta', Nature Communications, vol. 15, no. 1, pp. 1-21. Open access 3 3 198
2024	Yu, W, Truong, NT, Polara, R, Gargett, T, Tea, MN, Pitson, SM, Cockshell, MP, Bonder, CS, Ebert, LM & Brown, MP 2024, 'Endogenous bystander killing mechanisms enhance the activity of novel FAP-specific CAR-T cells against glioblastoma', Clinical and Translational Immunology, vol. 13, no. 7, pp. 1-20. Open access 3 2 4
2023	Bandara, V, Foeng, J, Gundsambuu, B, Norton, TS, Mills, SJ, Tan, LY, Thompson, EJ, Coombs, J, Cowin, AJ, Bonder, CS & Barry, SC and 15 other authors 2023, 'Pre-clinical validation of a pan-cancer CAR-T cell immunotherapy targeting nfP2X7', Nature Communications, vol. 14, no. 1, article no. 5546, pp. 1-17. Open access 13 15 6
2023	Myo Min, KK, Ffrench, CB, Jessup, CF, Shepherdson, M, Barreto, SG & Bonder, CS 2023, 'Overcoming the fibrotic fortress in pancreatic ductal adenocarcinoma: challenges and opportunities', Cancers, vol. 15, no. 8, pp. 1-19. Open access 8 9 45
2023	Myo Min, KK, Ffrench, CB, McClure, BJ, Ortiz, M, Dorward, EL, Samuel, MS, Ebert, LM, Mahoney, Mỹ & Bonder, CS 2023, 'Desmoglein-2 as a cancer modulator: friend or foe?', Frontiers in Oncology, vol. 13, article no. 1327478 , pp. 1-15. Open access 4 5 2
2023	Scheer, KG, Ebert, LM, Samuel, MS, Bonder, CS & Gomez, GA 2023, 'Bevacizumab-induced hypertension in glioblastoma patients and its potential as a modulator of treatment response', Hypertension, vol. 80, no. 8, pp. 1590-1597. Open access 7 6 4
2022	Blaszczak, W, Ahmed, A, Leithner, K, Schubert, A, Leech, M, Bonder, C & Tsagakis, I 2022, 'Outlook of women in science: an interview with our authors', Molecular Oncology, vol. 16, no. 5, pp. 1047-1056. Open access 16
2022	Burzava, AL, Jasieniak, M, Cockshell, MP, Voelcker, NH, Bonder, CS, Griesser, HJ & Moore, E 2022, 'Attachment of endothelial colony-forming cells onto a surface bearing immobilized anti-CD34 antibodies: Specific CD34 binding versus nonspecific binding', BioInterphases: An Open Access Journal for the Biomaterials Interface Community, vol. 17, no. 3, pp. 1-12. 1 1
2022	Ebert, LM, Vandyke, K, Johan, MZ, DeNichilo, M, Tan, LY, Myo Min, KK, Weimann, BM, Ebert, BW, Pitson, SM, Zannettino, AC, Wallington-Beddoe, CT & Bonder, CS 2022, 'Desmoglein-2 expression is an independent predictor of poor prognosis patients with multiple myeloma', Molecular Oncology, vol. 16, no. 6, pp. 1221-1240. Open access 11 12 13
2022	Myo Min, KK, Rojas-Canales, D, Penko, D, DeNichilo, M, Cockshell, MP, Ffrench, CB, Thompson, EJ, Asplund, O, Drogemuller, CJ, Prasad, RB, Groop, L, Grey, ST, Thomas, HE, Loudovaris, T, Kay, TW, Mahoney, MG, Jessup, CF, Coates, PT & Bonder, CS 2022, 'Desmoglein-2 is important for islet function and β-cell survival', Cell Death and Disease, vol. 13, no. 10, pp. 1-15. Open access 6 6 7
2022	Tan, LY, Cockshell, MP, Moore, E, Myo Min, KK, Ortiz, M, Johan, MZ, Ebert, B, Ruszkiewicz, A, Brown, MP, Ebert, LM & Bonder, CS 2022, 'Vasculogenic mimicry structures in melanoma support the recruitment of monocytes', OncoImmunology, vol. 11, no. 1, article no. e2043673, pp. 1-17. Open access 16 17 4
2021	Fouladzadeh, A, Dorraki, M, Min, KKM, Cockshell, MP, Thompson, EJ, Verjans, JW, Allison, A, Bonder, CS & Abbott, D 2021, 'The development of tumour vascular networks', Communications Biology, vol. 4, no. 1, article no. 1111, pp. 1-10. Open access 16 13 10
2021	Genovesi, LA, Puttick, S, Millar, A, Kojic, M, Ji, P, Lagendijk, AK, Brighi, C, Bonder, CS, Adolphe, C & Wainwright, BJ 2021, 'Patient-derived orthotopic xenograft models of medulloblastoma lack a functional blood-brain barrier', Neuro-Oncology, vol. 23, no. 5, pp. 732-742. Open access 16 15 7
2021	Martini, C, DeNichilo, M, King, DP, Cockshell, MP, Ebert, B, Dale, B, Ebert, LM, Woods, A & Bonder, CS 2021, 'CD36 promotes vasculogenic mimicry in melanoma by mediating adhesion to the extracellular matrix', BMC Cancer, vol. 21, no. 1, article no. 765. Open access 22 20 4
2021	Yang, GN, Strudwick, XL, Bonder, CS, Kopecki, Z & Cowin, AJ 2021, 'Increased expression of flightless I in cutaneous squamous cell carcinoma affects wnt/β-catenin signaling pathway', International Journal of Molecular Sciences, vol. 22, no. 24, article no. 13203, pp. 1-14. Open access 2 1
2020	Burzava, AL, Jasieniak, M, Cockshell, MP, Voelcker, NH, Bonder, CS, Griesser, HJ & Moore, E 2020, 'Surface-grafted hyperbranched polyglycerol coating: varying extents of fouling resistance across a range of proteins and cells', ACS Applied Bio Materials, vol.3, no. 6, pp. 3718-3730. 11 10 5
2020	Dorraki, M, Fouladzadeh, A, Allison, A, Bonder, CS & Abbott, D 2020, 'Angiogenic networks in tumors - insights via mathematical modeling', IEEE Access, vol. 8, pp. 43215-43228. Open access 8 7 11
2020	Ebert, LM, Yu, W, Gargett, T, Toubia, J, Kollis, PM, Tea, MN, Ebert, BW, Bonder, CS, Oksdath Mansilla, M, Scheer, KG, Perrin, SL, Pitson, SM, Gomez, GA & Brown, MP and 8 other authors 2020, 'Endothelial, pericyte and tumor cell expression in glioblastoma identifies fibroblast activation protein (FAP) as an excellent target for immunotherapy', Clinical and Translational Immunology, vol. 9, no. 10, article no. e1191. Open access 51 46 4
2020	Flemming, JP, Hill, BL, Haque, MW, Raad, J, Bonder, CS, Harshyne, LA, Rodeck, U, Luginbuhl, A, Wahl, JK, Tsai, KY, Wermuth, PJ, Overmiller, AM & Mahoney, M 2020, 'miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas', Journal of Extracellular Vesicles, vol. 9, no. 1, article no. 1790159, pp. 1-22. Open access 46 41 8
2020	Martini, C, Thompson, EJ, Hyslop, SR, Cockshell, MP, Dale, BJ, Ebert, LM, Woods, AE, Josefsson, EC & Bonder, CS 2020, 'Platelets disrupt vasculogenic mimicry by cancer cells', Scientific Reports, vol. 10, no. 1, article no. 5869, pp. 1-18. Open access 24 20 3
2020	Yang, GN, Strudwick, XL, Bonder, C, Kopecki, Z & Cowin, AJ 2020, 'Effect of flightless I expression on epidermal stem cell niche during wound repair', Advances in Wound Care, vol. 9, no. 4, pp. 161-173. Open access 11 10 1
2019	Elder, AS, Bersten, AD, Saccone, GT, Bonder, CS & Dixon, D-L 2019, 'Prevention and amelioration of rodent ventilation-induced lung injury with either prophylactic or therapeutic feG administration', Lung, vol. 197, no. 5, pp. 671-680. Open access 3 3
2019	Forget, A, Harding, FJ, Cockshell, MP, Penko, D, Rouzaud, C, Ahmadi, V, Marina, PF, Rojas-Canales, D, Bonder, CS, Coates, PTH, Waibel, M, Thomas, HE, Kay, TW, Loudovaris, T, Blencowe, A & Voelcker, NH 2019, 'Replica moulded poly(dimethylsiloxane) microwell arrays induce localized endothelial cell immobilization for coculture with pancreatic islets', BioInterphases: An Open Access Journal for the Biomaterials Interface Community, vol. 14, no. 1, article no. 011002, pp. 1-8. Open access 4
2019	Harper, RL, Maiolo, S, Ward, RJ, Seyfang, J, Cockshell, MP, Bonder, CS & Reynolds, PN 2019, 'BMPR2-expressing bone marrow-derived endothelial-like progenitor cells alleviate pulmonary arterial hypertension in vivo', Respirology, vol. 24, no. 11, pp. 1095-1103. Open access 26 23 5
2019	Neubauer, HA, Tea, MN, Zebol, JR, Gliddon, BL, Stefanidis, C, Moretti, PA, Pitman, MR, Costabile, M, Kular, J, Stringer, BW, Day, BW, Samuel, MS, Bonder, CS, Powell, JA & Pitson, SM 2019, 'Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma', Oncogene, vol. 38, pp. 1151-1165. Open access 22 20 5
2019	Toledo-Flores, D, Williamson, A, Schwarz, N, Fernando, S, Dimasi, C, Witt, TA, Nguyen, TM, Puranik, AS, Chue, CD, Delacroix, S, Spoon, DB, Bonder, CS, Bursill, CA, Di Bartolo, BA, Nicholls, SJ, Simari, RD & Psaltis, PJ 2019, 'Vasculogenic properties of adventitial Sca-1 ⁺ CD45 ⁺ progenitor cells in mice: a potential source of vasa vasorum in atherosclerosis', Scientific Reports, vol. 9, no. 1, article no. 7286,pp. 1-15. Open access 19 19 5
2019	Vidanapathirana, AK, Pullen, BJ, Zhang, R, Duong, MN, Goyne, JM, Zhang, X, Bonder, CS, Abell, AD, Bursill, CA, Nicholls, SJ & Psaltis, PJ 2019, 'A Novel Ruthenium-based Molecular Sensor to Detect Endothelial Nitric Oxide', Scientific Reports, vol. 9, no. 1, article no. 1720, pp. 1-16. Open access 9 8 6
2018	Cabezas, S, Bracho, G, Aloia, AL, Adamson, PJ, Bonder, CS, Smith, JR, Gordon, DL & Carr, JM 2018, 'Dengue virus induces increased activity of the complement alternative pathway in infected cells', Journal of Virology, vol. 92, no. 14, article no. e00633-18, pp. 1-20. Open access 33 30 2
2018	Hercus, TR, Kan, WL, Broughton, SE, Tvorogov, D, Ramshaw, HS, Thompson, EJ, McKenzie, DR, Tergaonkar, V, Hughes, T, Samuel, MS, Bonder, CS, Grimbaldeston, MA & Lopez, A F and 10 other authors 2018, 'Role of the β common (βc) family of cytokines in health and disease', Cold Spring Harbor Perspectives in Biology, vol. 10, no. 6, article no. a028514, pp. 1-26. Open access 36 28 14
2018	Hofma, BR, Wardill, HR, Mavrangelos, C, Campaniello, MA, Dimasi, D, Bowen, JM, Smid, SD, Bonder, CS, Beckett, EA & Hughes, PA 2018, 'Colonic migrating motor complexes are inhibited in acute tri-nitro benzene sulphonic acid colitis', PLoS One, vol. 12, no. 6, article no. e0199394, pp. 1-15. Open access 15 14 4
2018	Lidgerwood, GE, Pitson, SM, Bonder, C & Pébay, A 2018, 'Roles of lysophosphatidic acid and sphingosine-1-phosphate in stem cell biology', Progress in Lipid Research, vol. 72, pp. 42-54. Open access 31 32 6
2017	Bihari, S, Dixon, D-L, Lawrence, MD, De Bellis, D, Bonder, CS, Dimasi, DP & Bersten, AD 2017, 'Fluid-induced lung injury-role of TRPV4 channels', Pfluegers Archiv: European journal of physiology, vol. 469, no. 9, pp. 1121-1134. 23 21 1
2017	Burzava, AL, Jasieniak, M, Cockshell, MP, Bonder, CS, Harding, FJ, Griesser, HJ & Voelcker, NH 2017, 'Affinity binding of EMR2 expressing cells by surface-grafted chondroitin sulfate B', Biomacromolecules, vol. 18, no. 6, pp. 1697-1704. 5 5 1
2017	Chan, D, Green, S, Fiatarone Singh, MA, Barnard, R, Bonder, CS & Cheema, BS 2017, 'Effect of intradialytic resistance training on pulse wave velocity and associated cardiovascular disease biomarkers in end stage renal disease', Nephrology, vol. 23, no. 11, pp. 1055-1062. Open access 6 6 1
2017	Heng, S, Reineck, P, Vidanapathirana, AK, Pullen, BJ, Drumm, DW, Ritter, LJ, Schwarz, N, Bonder, CS, Psaltis, PJ, Thompson, JG, Gibson, BC, Nicholls, SJ & Abell, AD 2017, 'Rationally designed probe for reversible sensing of zinc and application in cells', ACS Omega, vol. 2, no. 9, pp. 6201-6210. Open access 23 22 68
2017	Pastore, ML, Studier, H, Bonder, CS & Roberts, M 2017, 'Non-invasive metabolic imaging of melanoma progression', Experimental Dermatology, vol. 26, no. 7, pp. 607-614. 40 35 1
2017	Rojas-Canales, D, Penko, D, Myo Min, KK, Parham, KA, Peiris, H, Haberberger, R V, Pitson, SM, Drogemuller, C, Keating, DJ, Grey, ST, Coates, PT, Bonder, CS & Jessup, CF 2017, 'Local sphingosine kinase 1 activity improves islet transplantation', Diabetes, vol. 66, no. 5, pp. 1301-1311. Open access 6 6 6
2017	Tan, LY, Martini, C, Fridlender, ZG, Bonder, CS, Brown, MP & Ebert, LM 2017, 'Control of immune cell entry through the tumour vasculature: a missing link in optimising melanoma immunotherapy?', Clinical and Translational Immunology, vol. 6, article no. e135, pp. 1-9. Open access 26 26 3
2016	Cockshell, MP & Bonder, CS 2016, 'Isolation and culture of human CD133+ non-adherent endothelial forming cells', Bio-protocol, vol. 6, no. 7, article no. e1772, pp. 1-12. Open access
2016	Dalilottojari, A, Delalat, B, Harding, FJ, Cockshell, MP, Bonder, CS & Voelcker, NH 2016, 'Porous silicon-based cell microarrays: optimizing human endothelial cell-material surface interactions and bioactive release', Biomacromolecules, vol. 17, no. 11, pp. 3724-3731. 7 6
2016	Dimasi, DP, Pitson, SM & Bonder, CS 2016, 'Examining the role of sphingosine kinase-2 in the regulation of endothelial cell barrier integrity', Microcirculation, vol. 23, no. 3, pp. 248-265. Open access 9 8 3
2016	Ebert, LM, Tan, LY, Johan, MZ, Min, KKM, Cockshell, MP, Parham, KA, Betterman, KL, Szeto, P, Boyle, S, Silva, L, Peng, A, Zhang, Y, Zannettino, AC, Gronthos, S, Koblar, S, Harvey, NL, Lopez, AF, Shackleton, M & Bonder, CS 2016, 'A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis', Angiogenesis, vol. 19, pp. 463-486. Open access 34 35
2016	Harper, R, Reynolds, A, Bonder, CS & Reynolds, P 2016, 'BMPR2 gene therapy for PAH acts via Smad and non-Smad signalling', Respirology, vol. 21, no. 4, pp. 727-733. Open access 37 37 2
2016	Moore, E, Zill, AT, Anderson, CA, Jochem, AR, Zimmerman, SC, Bonder, CS, Kraus, T, Thissen, H & Voelcker, NH 2016, 'Synthesis and conjugation of alkyne-functional hyperbranched polyglycerols', Macromolecular Chemistry and Physics, vol. 217, no. 20 , pp. 2252-2261. 10 10
2016	Neubauer, HA, Pham, DH, Zebol, JR, Moretti, PA, Peterson, AL, Leclercq, TM, Chan, H, Powell, JA, Pitman, MR, Samuel, MS, Bonder, CS, Creek, DJ, Gliddon, BL & Pitson, SM 2016, 'An oncogenic role for sphingosine kinase 2', Oncotarget, vol. 7, no. 40, pp. 64886-64899. Open access 52 49
2016	Pulford, E, Hocking, A, Griggs, K, McEvoy, J, Bonder, C, Henderson, D & Klebe, S 2016, 'Vasculogenic mimicry in malignant mesothelioma: an experimental and immunohistochemical analysis', Pathology, vol. 48, no. 7, pp. 650-659. Open access 16 16 461
2016	Sun, WY, Dimasi, DP, Pitman, MR, Zhuang, Y, Heddle, R, Pitson, SM, Grimbaldeston, MA & Bonder, CS 2016, 'Topical application of fingolimod perturbs cutaneous inflammation', Journal of Immunology, vol. 196, no. 9, pp. 3854-3864. Open access 14 13 11
2016	Tan, LY, Mintoff, C, Johan, MZ, Ebert, BW, Brown, MP, Bonder, CS & Ebert, LM and 8 other authors 2016, 'Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome', Oncotarget, vol. 7, no. 29, pp. 46492-46508. Open access 43 43 1
2015	Aloia, AL, Abraham, AM, Bonder, CS, Pitson, SM & Carr, JM 2015, 'Dengue Virus-Induced Inflammation of the Endothelium and the Potential Roles of Sphingosine Kinase-1 and MicroRNAs', Mediators of Inflammation, vol. 2015, article no. 509306, pp. 1-13. Open access 20 19 2
2015	Calvert, JK, Helbig, KJ, Dimasi, D, Cockshell, M, Beard, MR, Pitson, SM, Bonder, CS & Carr, JM 2015, 'Dengue virus infection of primary endothelial cells induces innate immune responses, changes in endothelial cells function and is restricted by interferon-stimulated responses', Journal of Interferon and Cytokine Research, vol. 35, no. 8, pp. 654-665. Open access 30 28
2015	Etemadi, N, Chopin, M, Anderton, H, Tanzer, MC, Rickard, JA, Abeysekera, W, Hall, C, Spall, SK, Wang, B, Xiong, Y, Hla, T, Pitson, SM, Bonder, CS, Wong, WW-L, Ernst, M, Smyth, GK, Vaux, DL, Nutt, SL, Nachbur, U & Silke, J 2015, 'TRAF2 regulates TNF and NF-kappa B signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1', eLife, vol. 4, article no. e10592, pp. 1-27. Open access 84 81 3
2015	Moldenhauer, LM, Cockshell, MP, Frost, L, Parham, KA, Tvorogov, D, Tan, LY, Ebert, LM, Tooley, K, Worthley, S, Lopez, AF & Bonder, CS 2015, 'Interleukin-3 greatly expands non-adherent endothelial forming cells with pro-angiogenic properties', Stem Cell Research, vol. 14, no. 3, pp. 380-395. Open access 16 15 4
2015	Parham, KA, Zebol, JR, Tooley, KL, Sun, WY, Moldenhauer, LM, Cockshell, MP, Gliddon, BL, Moretti, PA, Tigyi, G, Pitson, SM & Bonder, CS 2015, 'Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-γ that regulates neoangiogenesis', The FASEB Journal, vol. 29, no. 9, pp. 3638-3653. Open access 79 75 1
2015	Penko, D, Rojas-Canales, D, Mohanasundaram, D, Peiris, HS, Sun, WY, Drogemuller, CJ, Keating, DJ, Coates, PTH, Bonder, CS & Jessup, CF 2015, 'Endothelial progenitor cells enhance islet engraftment, influence beta cell function and modulate connexin 36 expression', Cell Transplantation, vol. 24, no. 1, pp. 37-48. Open access 29 27 40
2015	Pitman, MR, Powell, JA, Coolen, C, Moretti, PA, Zebol, JR, Pham, DH, Finnie, JW, Don, AS, Ebert, LM, Bonder, CS, Gliddon, BL & Pitson, SM 2015, 'A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties', Oncotarget, vol. 6, no. 9, pp. 7065-7083. Open access 64 61
2014	Hanf, W, Bonder, CS & Coates, PTH 2014, 'Transplant glomerulopathy: the interaction of HLA antibodies and endothelium', Journal of Immunology Research, vol. 2014, article no. 549315, pp. 1-11. Open access 22 21
2014	Parham, KA, Pitson, SM & Bonder, CS 2014, 'Regulation of EPCs: The Gateway to Blood Vessel Formation', New Journal of Science, vol. 2014, article no. 972043, pp. 1-16. Open access
2014	Peiris, H, Bonder, CS, Coates, PT, Keating, DJ & Jessup, CF 2014, 'The ß-cell/EC axis: how do islet cells talk to each other?', Diabetes, vol. 63, no. 1, pp. 3-11. Open access 90 82
2014	Ruzehaji, N, Kopecki, Z, Melville, E, Appleby, SL, Bonder, CS, Arkell, RM, Fitridge, R & Cowin, AJ 2014, 'Attenuation of flightless I improves wound healing and enhances angiogenesis in a murine model of type 1 diabetes', Diabetologia, vol. 57, no. 2, pp. 402-412. Open access 29 27
2013	Bonder, CS & Ebert, LM 2013, 'Fos-icking for control of angiogenesis : increasing the longevity of peritoneal dialysis', Kidney International, vol. 84, no. 6, pp. 1065-1067. 5 5
2013	Carr, JM, Mahalingam, S, Bonder, CS & Pitson, SM 2013, 'Sphingosine kinase 1 in viral infections', Reviews in Medical Virology, vol. 23 no. 2, pp. 73-84. 43 41
2013	Dimasi, D, Sun, WY & Bonder, CS 2013, 'Neutrophil interactions with the vascular endothelium', International Immunopharmacology, vol. 17, no. 4, pp. 1167-1175. 46 45
2013	Limaye, VS, Bonder, CS, Sun, WY, Lester, S, Roberts-Thomson, PJ & Blumbergs, P 2013, 'Levels of soluble adhesion molecules and their associations in inflammatory myositis', International Journal of Rheumatic Diseases, vol. 16, no. 1, pp. 99-101. 3 3
2012	Appleby, SL, Cockshell, MP, Pippal, JB, Thompson, EJ, Barrett, JM, Tooley, K, Sen, S, Sun, WY, Grose, R, Nicholson, I, Levina, V, Cooke, I, Talbo, G, Lopez, AF & Bonder, CS 2012, 'Characterization of a distinct Population of Circulating Human Non-Adherent Endothelial Forming Cells and Their Recruitment via Intercellular Adhesion Molecule-3', PLoS One, vol. 7, no. 11, article no. e46996, pp. 1-15. Open access 20 21
2012	Broughton, SE, Dhagat, U, Hercus, TR, Nero, TL, Grimbaldeston, MA, Bonder, CS, Lopez, AF & Parker, MW 2012, 'The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling', Immunological Reviews, vol. 250, no. 1, pp. 277-302. 204 187
2012	Sun, WY & Bonder, CS 2012, 'Sphingolipids: a potential molecular approach to treat allergic inflammation', Journal of Allergy, vol. 2012, Article ID. 154174, pp. 1-14. Open access
2012	Sun, WY, Abeynaike, LD, Escarbe, S, Smith, CD, Pitson, SM, Hickey, MJ & Bonder, CS 2012, 'Rapid histamine-induced neutrophil recruitment is sphingosine kinase-1 dependent', American Journal of Pathology, vol. 180, no. 4, pp. 1740-1750. 22 23
2011	Barrett, JM, Parham, KA, Pippal, JB, Cockshell, MP, Moretti, PA, Brice, SL, Pitson, S & Bonder, C 2011, 'Over-expression of sphingosine kinase-1 enhances a progenitor phenotype in human endothelial cells', Microcirculation, vol. 18 no. 7, pp. 583-597. 10 10
2011	Jessup, CF, Bonder, CS, Pitson, SM & Coates, PTH 2011, 'The sphingolipid rheostat: a potential target for improving pancreatic islet survival and function', Endocrine Metabolic and Immune Disorders - Drug Targets, vol. 11, no. 4, pp. 262-272. 29
2011	Penko, D, Mohanasundaram, D, Sen, S, Drogemuller, C, Mee, C, Bonder, CS, Coates, PTH & Jessup, CF 2011, 'Incorporation of endothelial progenitor cells into mosaic pseudoislets', Islets, vol. 3, no. 3, pp. 73-79. Open access 27 27
2011	Pitson, SM, Powell, JA & Bonder, CS 2011, 'Regulation of sphingosine kinase in hematological malignancies and other cancers', Anti-Cancer Agents in Medicinal Chemistry, vol. 11, no. 9, pp. 799-809. 22 22
2011	Sen, S, McDonald, SP, Coates, PTH & Bonder, CS 2011, 'Endothelial progenitor cells : Novel biomarker and promising cell therapy for cardiovascular disease', Clinical Science, vol. 120, no. 7, pp. 263-283. Open access 188 174
2010	Sun, WY, Pitson, S & Bonder, C 2010, 'Tumor necrosis factor-induced neutrophil adhesion occurs via sphingosine kinase-1-dependent activation of endothelial a 5<U+00df> 1 integrin', American Journal of Pathology, vol. 177 no. 1, pp. 436-446. Open access 32 30
2010	Wang, H, Paton, J, Thorpe, CM, Bonder, CS, Sun, WY & Paton, A 2010, 'Tissue factor-dependent procoagulant activity of subtilase cytotoxin, a potent AB5 toxin produced by Shiga toxigenic Escherichia coli', Journal of Infectious Diseases, vol. 202, no. 9, pp. 1415-1423. Open access 12 10
2008	Andonegui, G, Liu, L, Bonder, CS & Kerfoot, S 2008, 'Exogenous stromal cell-derived factor-1 induces modest leukocyte recruitment in vivo', American Journal of Physiology: Heart and Circulatory Physiology, vol. 294, no. 6, pp. 2524-2534. 10 10
2008	Gamble, JR, Pitson, SM, Bonder, C, Xia, P, Stankovic, M, Proia, RL, Vadas, M, Hahn, CN, Parsons, M & Li, X 2008, 'Basal and angiopoietin-1 mediated endothelial permeability is regulated by sphingosine kinase-1', Blood, vol. 111 no. 7, pp. 3489-3497. 76
2008	Norman, M, Yamanouchi, J, Bonder, CS, Hwang, J, Hulliger, S, Santamaria, P & Kubes, P 2008, 'Mast cells regulate the magnitude and the cytokine microenvironment of the contact hypersensitivity response', American Journal of Pathology, vol. 172, no. 6, pp. 1638-1649. Open access 42 43

Research

Patents

Details	Registry	Status
Anti-fouling and/or anti-thrombotic medical devices Voelcker, Nicolas Hans; Moore, Eli; Bonder, Claudine Sharon	AU	Filed
Markers of endothelial progenitor cells and uses thereof Bonder, Claudine Sharon; Lopez, Angel Fransciso; Talbo, Gert Hoy	AU	Granted
Markers of endothelial progenitor cells and uses thereof Bonder, Claudine Sharon; López, Ángel Fransciso; Talbo, Gert Hoy	EP	Filed
Markers of endothelial progenitor cells and uses thereof Bonder, Claudine Sharon; Lopez, Angel Fransciso; Talbo, Gert Hoy	US	Filed
Markers of endothelial progenitor cells and uses thereof Bonder, Claudine Sharon; Lopez, Angel Fransciso; Talbo, Gert Hoy	WO	Filed
Medical devices using coated polymers Moore, Eli; Benveniste, Glen Leon; Bonder, Claudine Sharon	WO	Filed
Method of culturing cells Bonder, Claudine Sharon; Lopez, Angel Fransciso	WO	Filed
Novel cancer treatment involving modulation of il-3 activity Lopez, Angel F; Bonder, Claudine S; Thompson, Emma	WO	Filed

External engagement & recognition

Collaborations

Highlights

2020-present: Scientific advisor for Carina Biotech Ltd and previously TekCyte Pty Ltd (both start-up comapnies from CTM-CRC)

External engagement & recognition

Collaborations

Organisation	Country
Australian National University	AUSTRALIA
Australian Research Council (ARC)	AUSTRALIA
Baker Heart and Diabetes Institute	AUSTRALIA
Beatson Institute	UNITED KINGDOM
BreastScreen SA	AUSTRALIA
Central Adelaide Local Health Network Incorporated	AUSTRALIA
Centre for Physical Activity in Ageing	AUSTRALIA
Cornell University	UNITED STATES
CSIRO Manufacturing Flagship	AUSTRALIA
Flinders Medical Centre	AUSTRALIA
Flinders University	AUSTRALIA
Garvan Institute of Medical Research	AUSTRALIA
Garvan Medical Institute	AUSTRALIA
German Cancer Research Center	GERMANY
Griffith University	AUSTRALIA
H. Lee Moffitt Cancer Center	UNITED STATES
Hanson Centre for Cancer Research	AUSTRALIA
Hanson Institute	AUSTRALIA
Hebrew University	MEXICO
Institute of Medical and Veterinary Science	AUSTRALIA
La Trobe University	AUSTRALIA
Lancaster University	UNITED KINGDOM
Leibniz Institute for New Materials	GERMANY
Lund University	SWEDEN
Mayo Clinic	UNITED STATES
Medical University of Graz	AUSTRIA
Medical University of South Carolina	UNITED STATES
Molecular Oncology Editorial Office	UNITED KINGDOM
Monash University	AUSTRALIA
Peter MacCallum Cancer Centre	AUSTRALIA
QIMR Berghofer Medical Research Institute	AUSTRALIA
RMIT University	AUSTRALIA
Royal Adelaide Hospital	AUSTRALIA
Royal Brisbane and Women's Hospital	AUSTRALIA
Royal College of Surgeons in Ireland	IRELAND
Royal Eye & Ear Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
Shanghai University	CHINA
South Australian Health and Medical and Research Institute (SAHMRI)	AUSTRALIA
St. Vincent's Institute of Medical Research	AUSTRALIA
The Queen Elizabeth Hospital	AUSTRALIA
Thomas Jefferson University	UNITED STATES
Trinity College Dublin	IRELAND
Tufts Medical Centre	UNITED STATES
Universitat Freiburg im Breisgau	GERMANY
University of Adelaide	AUSTRALIA
University of Canberra	AUSTRALIA
University of Illinois at Urbana-Champaign	UNITED STATES
University of Melbourne	AUSTRALIA
University of Nebraska Medical Center	UNITED STATES
University of New South Wales	AUSTRALIA
University of Oxford	UNITED KINGDOM
University of Queensland	AUSTRALIA
University of Sheffield	UNITED KINGDOM
University of South Australia	AUSTRALIA
University of Sydney	AUSTRALIA
University of Tennessee	UNITED STATES
University of Zurich	SWITZERLAND
Walter and Eliza Hall Institute of Medical Research	AUSTRALIA
Washington University in St Louis	UNITED STATES
Western Sydney University	AUSTRALIA
Women's and Children's Health Network	AUSTRALIA

External engagement & recognition

Engagement/recognition	Year
Medal of the Order of Australia (OAM) Governer General of the Commonwealth of Australia	2025
Ambassador Bridging the Gap	2019
Project Leader Cell Therapy Manufacturing Co-operative Research Centre (CTM-CRC)	2018
Ambassador Bridging The Gap Foundation	2017
Member North American Vascular Biology Organisation (NAVBO)	2017
Member Australasian Society for Immunology (ASI)	2017
Member Australian and New Zealand Microcirculation Society (ANZMS)	2017
Member Australian Society for Medical Research (ASMR)	2017
Member American Association of Immunologists (AAI)	2017
Member Australian Vascular Biology Society (AVBS)	2017
Project Leader Cell Therapy Manufacturing Co-operative Research Centre (CTM-CRC)	2017
Emerging Innovator Award Winnovation Awards	2016
Project Leader Cell Therapy Manufacturing Co-operative Research Centre (CTM-CRC)	2016
Project Leader Cell Therapy Manufacturing Co-operative Research Centre (CTM-CRC)	2015
Project Leader Cell Therapy Manufacturing Co-operative Research Centre (CTM-CRC)	2014
Finalist, Peter Doherty Leading Light Award Australian Society for Medical Research (ASMR)	2013
Project Leader Cell Therapy Manufacturing Co-operative Research Centre (CTM-CRC)	2013
Project Leader Co-operative Research Centre for Biomarker Translation (Biomarker CRC)	2012
Project Leader Co-operative Research Centre for Biomarker Translation (Biomarker CRC)	2011
Project Leader Co-operative Research Centre for Biomarker Translation (Biomarker CRC)	2010

Other

Invited media contact for Pankind the National Breast Cancer Foundation (NBCF), The Hospital Research Foundation (THRF), and the Centre for Cancer Biology.

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
110188-Enhancing therapy of acute myeloid leukaemia by predicting drivers of relapse	Current
642 - Investigating causes of congenital heart and vascular defects	Current
Advancing a novel biomarker for pancreatic cancer	Current
Characterisation of extracellular matrix composition across the human brain and applications in brain organoid vascularisation	Current
Deciphering how airway epithelial programming and inflammation cause chronic allergic airways disease	Current
Enhancing cancer immunotherapy success by efficient recruitment of T cells to solid tumours	Current
Interleukin-3 (IL-3) promotes blood vessel development in breast cancer	Current
Investigating the origins and progression of pancreatic cancer	Current
Molecular diagnosis for point-of-care skin cancer testing	Current
Revealing the role of ICAM1 in breast cancer progression	Current
Tumour protein D54 as a regulator of melanoma progression	Current
Understanding how cancers modify the functional characteristics of the tumour extracellular matrix	Current
Design and evaluation of blood-contacting coatings	Completed
Desmoglein-2 as a regulator of pancreatic ductal adenocarcinoma progression	Completed
Fundamental studies of poly(ethylene glycol-b-caprolactone) block copolymers self-assembly in water	Completed
Peroxisome proliferator-activated receptor gamma interacts with sphingosine 1-phosphate to regulate vascular function	Completed
Targeting sphingolipid metabolism in proteasome inhibitor-resistant multiple myeloma	Completed
Targeting sphingosine kinase 1 to overcome venetoclax resistance in acute myeloid leukemia	Completed
The role of flightless I in epidermal stem cell division, proliferation and differentiation during development, homeostasis, wound healing and epidermolysis bullosa-cutaneous squamous cell carcinoma	Completed
The role of platelets in vasculogenic mimicry	Completed
Transcriptional control of cellular identity in the lymphatic vasculature	Completed
Using high throughput screening to design cell therapy scaffolds	Completed
Vasculogenic mimicry: regulation and function in melanoma	Completed

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Professor Claudine Bonder

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Experience

Qualifications

Work history

Research

Research focus

Highlights

Projects

Outputs

Highlights

Journal Articles

Current research & highlights

Patents

External engagement & recognition

Collaborations

Highlights

Collaborations

External engagement & recognition

Medal of the Order of Australia (OAM)

Ambassador

Project Leader

Ambassador

Member

Member

Member

Member

Member

Member

Project Leader

Emerging Innovator Award

Project Leader

Project Leader

Project Leader

Finalist, Peter Doherty Leading Light Award

Project Leader

Project Leader

Project Leader

Project Leader

Other

Teaching & student supervision

Courses and programs

Research degree supervision

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