Cory is interested in tissue growth and injury repair research. He leads the Bone Growth and Repair Research Group at University of South Australia. He is established as a leading researcher in paediatric bone biology and cancer chemotherapy-induced bone defects. He has more than 170 publications (including journals: J Bone Miner Res, Endocr Rev, Endocrinology, Nat Rev Rheumatol, Hum Mol Genet, Am J Pathol, Am J Physiol Endocr Metab, PloS One, Bone, J Cell Physiol, and Sci Rep). Cory is Managing Editor for Frontiers in Bioscience, Guest Editor for Journal of Molecular Endocrinolology, Guest Editor for International Journal of Endocrinology, and is an editorial board member for 8 other journals including Scientific Reports.
... Read moreAbout me
Cory is interested in tissue growth and injury repair research. He leads the Bone Growth and Repair Research Group at University of South Australia. He is established as a leading researcher in paediatric bone biology and cancer chemotherapy-induced bone defects. He has more than 170 publications (including journals: J Bone Miner Res, Endocr Rev, Endocrinology, Nat Rev Rheumatol, Hum Mol Genet, Am J Pathol, Am J Physiol Endocr Metab, PloS One, Bone, J Cell Physiol, and Sci Rep). Cory is Managing Editor for Frontiers in Bioscience, Guest Editor for Journal of Molecular Endocrinolology, Guest Editor for International Journal of Endocrinology, and is an editorial board member for 8 other journals including Scientific Reports.
Cory's current research interests: (1) Bone growth mechanisms and regulation; (2) Mechanisms for injury responses and bone growth defects after growth plate fracture; (3) Development of biological treatments (growth factors or stem cells based) for repairing injured growth plate cartilage and for enhancing bone fracture healing; (4) Mechanisms for chemotherapy-induced bone growth arrest and osteoporosis and development of preventative treatments; (5) Improvement of bone health using natural bioactive compounds and nutraceuticals.
Cory is a member of Bone Health Foundation Research Committee (Australia), and a former member of Channel-7 Children's Research Foundation of South Australia Research Committee.
About me
Cory serves as editorial board members for eight international scientific journals. He is a member of more than 10 biomedical and clinical research professional societies. He serves as a member of Bone Health Foundation Research Committee and as a member of Channel-7 Children's Research Foundation Research Committee.
About me
Doctor of Philosophy Murdoch University
Master of Rural Science University of New England
Bachelor of Agricultural Science South China Agricultural University
Cory has a long-standing track record in research on tissue growth, injury repair and roles of growth factors. Since 2002, he has focused his research on bone growth, injury and repair, an exciting area of paediatric bone biology that is relatively unexplored and yet scientifically challenging and clinically critically impacting on children’s bone growth, bone mass accumulation, and adult bone health. His group mainly focuses on the following three areas:
(1) Mechanisms of normal bone growth and regulation: We are interested in understanding the mechanisms for the normal bone growth and currently we are focusing on understanding the growth plate biology and regulation of bone lengthening. We are also investigating whether... Read more
Research
Excludes commercial-in-confidence projects.
NT-3 as an upstream and potentially master regulator promoting bone fracture healing, NHMRC - Project Grant, 01/01/2017 - 31/12/2021
Preventing childhood glucocorticoid therapy-induced bone growth defects by blocking the aggravated chemokine SDF-1 signalling, Channel 7 Children's Research Foundation of SA, 14/11/2016 - 31/12/2018
Preventing childhood methotrexate chemotherapy-induced bone loss by blocking the aggravated proosteoclastogenic cytokine - NF-kB signalling, Channel 7 Children's Research Foundation of SA, 01/01/2016 - 31/12/2017
Bone growth for healthy development: physiology, pathophysiology, and regeneration, NHMRC - Research Fellowship, 01/01/2013 - 31/12/2017
Experimental and computational study on biomechanical behavior of osteocytes, NHMRC - Postgraduate Research Scholarship, 01/01/2015 - 14/03/2017
Mobilisation of endogenous mesenchymal progenitor cells for growth plate regeneration, NHMRC - Project Grant, 01/01/2013 - 31/12/2016
Research
Research outputs for the last seven years are shown below. To see earlier years visit ORCID, ResearcherID or Scopus
Open access indicates that an output is open access.
Year | Output |
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2016 |
Open access
38
38
1
|
2016 |
Open access
49
39
|
Year | Output |
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2013 |
|
2013 |
|
2012 |
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2012 |
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2012 |
2
|
2010 |
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Year | Output |
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2022 |
Open access
1
1
1
|
2022 |
Open access
2
|
2022 |
Open access
1
|
2022 |
Open access
1
2
1
|
2022 |
Open access
2
2
2
|
2022 |
Open access
2
|
2022 |
Open access
2
4
|
2021 |
Open access
2
2
1
|
2021 |
Open access
2
2
|
2021 |
Open access
6
6
1
|
2021 |
Open access
1
1
|
2021 |
Open access
14
13
1
|
2021 |
3
3
32
|
2021 |
Open access
14
15
|
2021 |
Open access
4
3
1
|
2021 |
Open access
1
1
|
2020 |
Open access
75
78
1
|
2020 |
3
2
|
2020 |
Open access
30
28
389
|
2020 |
Open access
12
10
|
2019 |
Open access
15
13
|
2019 |
8
7
|
2019 |
Open access
83
79
1
|
2019 |
Open access
11
10
|
2019 |
Open access
12
10
5
|
2019 |
12
13
|
2019 |
Open access
10
10
|
2019 |
7
8
|
2019 |
Open access
10
12
3
|
2019 |
Open access
10
12
|
2019 |
Open access
2
2
1
|
2019 |
Open access
6
4
|
2019 |
Open access
1
1
1
|
2019 |
Open access
6
6
15
|
2019 |
4
4
|
2019 |
25
16
4
|
2019 |
Open access
8
7
|
2019 |
Open access
25
24
10
|
2018 |
Open access
6
3
|
2018 |
15
11
|
2018 |
42
40
|
2018 |
40
41
1
|
2018 |
Open access
33
30
1
|
2018 |
Open access
11
10
1
|
2018 |
Open access
7
7
1
|
2018 |
Open access
58
54
|
2018 |
14
14
1
|
2018 |
Open access
15
14
|
2018 |
Open access
36
30
|
2018 |
Open access
14
12
1
|
2018 |
Open access
11
8
3
|
2018 |
Open access
16
17
1
|
2018 |
Open access
9
7
|
2018 |
Open access
14
12
|
2018 |
Open access
10
9
|
2018 |
17
17
|
2018 |
Open access
9
10
|
2018 |
Open access
29
28
|
2018 |
22
22
|
2018 |
Open access
43
45
1
|
2018 |
18
18
|
2018 |
Open access
7
6
|
2017 |
Open access
6
6
|
2017 |
26
24
2
|
2017 |
Open access
11
10
|
2017 |
Open access
3
2
|
2017 |
Open access
32
33
1
|
2017 |
Open access
69
67
4
|
2017 |
Open access
20
15
15
|
2017 |
Open access
8
6
|
2017 |
Open access
57
54
|
2017 |
Open access
45
44
1
|
2017 |
Open access
35
34
1
|
2017 |
Open access
18
15
1
|
2016 |
Open access
13
10
|
2016 |
Open access
10
8
|
2016 |
Open access
38
38
1
|
2016 |
Open access
24
23
|
2016 |
Open access
13
10
2
|
2016 |
Open access
23
20
1
|
2016 |
Open access
49
39
|
2016 |
Open access
17
17
|
2016 |
Open access
6
4
|
2016 |
Open access
17
10
|
2016 |
Open access
6
4
|
2016 |
Open access
55
50
1
|
2016 |
Open access
40
37
32
|
2016 |
Open access
11
9
|
2015 |
Open access
12
8
1
|
2015 |
Open access
11
8
3
|
2015 |
Open access
17
15
|
2015 |
Open access
5
20
|
2015 |
Open access
26
29
|
2015 |
Open access
52
47
|
2015 |
Open access
12
11
|
2015 |
Open access
22
21
7
|
2015 |
Open access
4
4
4
|
2015 |
Open access
6
6
|
2014 |
Open access
38
39
2
|
2014 |
Open access
46
31
1
|
2014 |
Open access
30
24
|
2014 |
Open access
1
2
|
2014 |
Open access
8
8
1
|
2014 |
Open access
10
29
1
|
2014 |
Open access
55
51
1
|
2014 |
Open access
6
4
2
|
2014 |
Open access
100
97
1
|
2014 |
Open access
31
29
|
2014 |
Open access
35
31
5
|
2013 |
Open access
11
8
|
2013 |
Open access
33
28
4
|
2013 |
Open access
39
38
|
2013 |
Open access
35
32
|
2013 |
172
155
3
|
2013 |
Open access
41
39
|
2013 |
Open access
6
12
|
2013 |
Open access
16
26
1
|
2013 |
Open access
5
22
|
2012 |
122
77
|
2012 |
Open access
42
35
|
2012 |
Open access
24
23
|
2012 |
Open access
|
2012 |
52
50
|
2012 |
74
70
|
2012 |
Open access
18
15
|
2012 |
Open access
24
24
|
2012 |
Open access
38
37
|
2012 |
46
44
|
2012 |
44
38
|
2012 |
Open access
33
32
|
2012 |
39
34
|
2012 |
31
29
|
2012 |
Open access
39
37
|
2011 |
Open access
26
|
2011 |
Open access
26
25
|
2011 |
35
31
|
2011 |
143
126
|
2011 |
22
20
|
2011 |
Open access
29
|
2011 |
Open access
8
7
|
2011 |
Open access
39
31
|
2011 |
73
65
|
2010 |
41
37
|
2010 |
Open access
|
2009 |
53
50
|
2009 |
67
57
|
2009 |
45
43
|
2009 |
70
61
|
2009 |
Li, F, Li, L, Song, X-Y, Zhong, J, Luo, XG, Xian, CJ & Zhou, X-F 2009, 'Preconditioning selective ventral root injury promotes plasticity of ascending sensory neurons in the injured spinal cord of adult rats - Possible roles of brain-derived neurotrophic factor, TrkB and p75 neurotrophin receptor', European Journal of Neuroscience. |
2009 |
132
116
|
2009 |
21
19
|
2008 |
Macsai, C, Foster, B & Xian, CJ 2008, 'Roles of Wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair', Journal of Cellular Physiology. |
2008 |
46
40
|
Year | Output |
---|---|
2021 |
1
1
|
2020 |
1
|
2016 |
Open access
|
Research
Cory has a long-standing track record in research on tissue growth, injury repair and roles of growth factors. Since 2002, he has focused his research on bone growth, injury and repair, an exciting area of paediatric bone biology that is relatively unexplored and yet scientifically challenging and clinically critically impacting on children’s bone growth, bone mass accumulation, and adult bone health. His group mainly focuses on the following three areas:
(1) Mechanisms of normal bone growth and regulation: We are interested in understanding the mechanisms for the normal bone growth and currently we are focusing on understanding the growth plate biology and regulation of bone lengthening. We are also investigating whether some micro-nutrients can be used to positively modulate bone growth, bone mass accumulation, populations of skeletal stem cells, and adult bone health outcomes (such as osteoporosis and fractures).
(2) Mechanisms for growth plate trauma injury-induced growth defects: Growth plate trauma injury is a common and significant problem as 20% childhood bone fractures involve growth plate and the inured growth plate cartilage is often undesirably repaired by bony tissue leading to growth defects. Cory's group has been investigating cellular and molecular mechanisms for the faulty repair and developing growth factor- and/or stem cell- based repair.
(3) Mechanisms for and prevention of cancer chemotherapy-induced growth defects: While chemotherapy-based cancer treatment is becoming more successful and thus the use of chemotherapy is becoming more intensified, chemotherapy-induced long-term side effects are becoming more obvious as it stunts the bone growth and causes osteoporosis and frequent bone fractures which persists into adulthood. Cory's group is investigating the underlying cellular and molecular mechanisms for the bone growth defects and regeneration potentials of bone and bone marrow. This group also aims to develop supplementary preventative treatment that will preserve bone growth during chemotherapy.
External engagement & recognition
Organisation | Country |
---|---|
940th Hospital of Joint Logistic Support Force, People's Liberation Army of China | CHINA |
Academy of Orthopaedics of Guangdong Province | CHINA |
Affiliated Hospital of Hebei University of Engineering | CHINA |
Affiliated Huaian Hospital of Xuzhou Medical University | CHINA |
Beijing Agricultural Technology Extension Centre | CHINA |
Central South University | CHINA |
China Agricultural University | CHINA |
China University of Mining and Technology | CHINA |
Chinese Academy of Agricultural Sciences | CHINA |
Chinese Academy of Sciences | CHINA |
Chongqing University of Science and Technology | CHINA |
Daping Hospital | CHINA |
Emu Tracks Australasia Pty Ltd | AUSTRALIA |
Ferris State University | UNITED STATES |
First Affiliated Hospital of Harbin Medical University | CHINA |
Flinders Medical Centre | AUSTRALIA |
Flinders University | AUSTRALIA |
Guangdong Food and Drug Vocational-technical School | CHINA |
Guangdong General Hospital | CHINA |
Guangdong University of Technology | CHINA |
Guangxi Medical University | CHINA |
Guangzhou University of Chinese Medicine | CHINA |
Harbin Medical University | CHINA |
Harvard University | UNITED STATES |
Hong Kong Baptist University | HONG KONG |
Hunan University of Science and Technology | CHINA |
Institute of Medical and Veterinary Science | AUSTRALIA |
Islamic Azad University | IRAN |
Islamic Azad University Shahrekord Branch | IRAN |
Jiangsu Province Hospital | CHINA |
Jinan University | CHINA |
Kunming Medical University | CHINA |
La Trobe University | AUSTRALIA |
Lanzhou Command of CPLA | CHINA |
Lanzhou General Hospital | CHINA |
Lanzhou University | CHINA |
Lanzhou University of Technology | CHINA |
Luoyang Orthopedic Hospital of Henan Province | CHINA |
Macao University of Science and Technology | CHINA |
Mazandaran University of Medical Sciences | IRAN |
Nanjing Medical University | CHINA |
National Formosa University | TAIWAN |
National Institutes of Health | UNITED STATES |
National Taipei University of Technology | TAIWAN |
Ningbo No. 6 Hospital | CHINA |
Ningbo University | CHINA |
Ningxia Medical College | CHINA |
North-Eastern University | THAILAND |
Northwest A&F University | CHINA |
Northwestern Polytechnical University | CHINA |
Orthopedic Institute of Henan Province | UNITED STATES |
Peking Union Medical College Hospital | CHINA |
Provincial People's Hospital | CHINA |
Queensland University of Technology | AUSTRALIA |
Royal Adelaide Hospital | AUSTRALIA |
Royal Hospital for Sick Children | UNITED KINGDOM |
Rush University | UNITED STATES |
SA Pathology | AUSTRALIA |
Second People's Hospital of Pingxiang | CHINA |
Second Xiangya Hospital of Central-South University | CHINA |
Shandong University | CHINA |
Shanghai Jiao Tong University | CHINA |
Shenyang Agricultural University | CHINA |
Shenzhen People's Hospital | CHINA |
Shenzhen Sixth People's Hospital, China | CHINA |
Shenzhen University | CHINA |
Shiraz University Of Medical Sciences | IRAN |
South Australian Prostate Cancer Clinical Outcomes Collaborative (SA-PCCOC) | AUSTRALIA |
Southern Medical University | CHINA |
Sun Yat-Sen University | CHINA |
Taipei Medical University | TAIWAN |
Third Affiliated Hospital of Southern Medical University | CHINA |
Third Military Medical University | CHINA |
Tianjin Hospital | CHINA |
Tianjin Medical University | CHINA |
Tongji University | CHINA |
Università degli Studi di Camerino | ITALY |
Universita' di Camerino | ITALY |
University of Adelaide | AUSTRALIA |
University of Chinese Medicine | CHINA |
University of Melbourne | AUSTRALIA |
University of Minnesota, Twin Cities | UNITED STATES |
University of Newcastle | AUSTRALIA |
University of Queensland | AUSTRALIA |
University of South Australia | AUSTRALIA |
University of Southern Queensland | AUSTRALIA |
University of Sydney | AUSTRALIA |
University of Toronto | CANADA |
University of Western Australia | AUSTRALIA |
Wenzhou Medical University | CHINA |
Women's and Children's Health Network | AUSTRALIA |
Women's and Children's Hospital | AUSTRALIA |
Xuzhou Clinical College of Nanjing Medical University | CHINA |
Yanshan University | CHINA |
Youjiang Medical University for Nationalities | CHINA |
Yue Bei People's Hospital | CHINA |
Zhengzhou University | CHINA |
External engagement & recognition
Engagement/recognition | Year |
---|---|
Editorial Board MemberScientific Reports (Nature Publishing Group) |
2018 |
MemberChannel-7 Children's Research Foundation Research Committee |
2018 |
MemberBone Health Foundation Research Committee |
2018 |
MemberChannel-7 Children's Research Foundation Research Committee |
2017 |
MemberBone Health Foundation Research Committee |
2017 |
Project Grant: NT-3 as an upstream and potentially master regulator promoting bone fracture healingNational Health and Medical Research Council (NHMRC) |
2017 |
Project GrantNational Health and Medical Research Council (NHMRC) |
2016 |
Research FellowshipNational Health and Medical Research Council (NHMRC) |
2013 |
Senior Research FellowshipNational Health and Medical Research Council (NHMRC) |
2008 |
Teaching & student supervision
Supervisions from 2010 shown
Thesis title | Student status |
---|---|
Experimental and numerical assessment of temperature and force and their relationship in bone drilling | Current |
Characterization of proBDNF knock out mice and effect of proBDNF on angiogenesis | Completed |
Pathophysiology of bone marrow micro-vascular system damage and potency of flavonoids in recovery of bone marrow micro-vasculature following methotrexate therapy in rats | Completed |
Potential function of neurotrophic factors in growth plate cartilage bony repair and skeletal cell formation | Completed |
Potential protective effects of supplementation with nutraceuticals in preventing chemotherapy-induced bone loss in rats | Completed |
Potential regulatory roles of miRNA(s) in bone loss and marrow adiposity following methotrexate treatment in rats | Completed |
Roles of bone morphogenetic protein signalling in the bony repair of injured growth plate cartilage in young rats | Completed |
Roles of chemokine CXCL12 in bone growth defects induced by methotrexate and dexamethasone chemotherapeutic treatment | Completed |
Roles of Notch2 signalling pathway in bone & bone marrow micro-vasculature damage following methotrexate chemotherapy in rats | Completed |
The effect of different degrees of loading on the biomechanical responses of bone cells: understanding the role of mechanical stimuli on functional behaviour of bone | Completed |
The 'not-so-sweet' effects of maternal sweetened beverage consumption during pregnancy and lactation on metabolic outcomes in the adult rat and her offspring | Completed |