Dr Dave Yip

Adjunct Research Fellow Centre for Cancer Biology

City West Campus (HB11-25)
tel +61 8 830 27929

email Dave.Yip@unisa.edu.au

Research Degree Supervisor

Research

Research focus

Clinical Sciences
Oncology and Carcinogenesis
Pharmacology and Pharmaceutical Sciences
Biochemistry and Cell Biology
Immunology

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included.

Open access indicates that an output is open access.

Journal Articles

Year	Output
2025	Kan, WL, Weekley, CM, Nero, TL, Hercus, TR, Yip, KH, Tumes, DJ, Woodcock, JM, Ross, DM, Thomas, D, Terán, D, Owczarek, CM, Liu, NW, Martelotto, LG, Polo, JM, Pant, H, Tvorogov, D, Lopez, AF & Parker, MW 2025, 'The β common cytokine receptor family reveals new functional paradigms from structural complexities', Immunological Reviews, vol. 329, no. 1, pp. 1-25. Open access 1 2 1
2024	Perkins, GB, Tunbridge, MJ, Hurtado, PR, Zuiani, J, Mhatre, S, Yip, KH, Le, TTA, Yuson, C, Kette, F & Hissaria, P 2024, 'PEGylated liposomes for diagnosis of polyethylene glycol allergy', Journal of Allergy and Clinical Immunology, vol. 154, no. 2, pp. 503-507.e1. Open access 8 7
2024	Wang, H, Yip, KH, Keam, SP, Vlahos, R, Nichol, K, Wark, P, Toubia, J, Kral, AC, Cildir, G, Pant, H, Hercus, TR, Wilson, N, Owczarek, C, Lopez, AF, Bozinovski, S & Tumes, DJ 2024, 'Dual inhibition of airway inflammation and fibrosis by common β cytokine receptor blockade', Journal of Allergy and Clinical Immunology, vol. 153, no. 3, pp. 672-683.e6. Open access 7 5 67
2023	Pant, H, Hercus, TR, Tumes, DJ, Yip, KH, Parker, MW, Owczarek, CM, Lopez, AF & Huston, DP 2023, 'Translating the biology of β common receptor-engaging cytokines into clinical medicine', Journal of Allergy and Clinical Immunology, vol. 151, no. 2, pp. 324-344. Open access 13 8 1
2023	Yip, KH, Chao, J, Coolen, C, Pant, H, Kral, A, Smith, W, Schwarz, Q, Grimbaldeston, MA, Pitson, S, Lopez, AF, Woodcock, J & Tumes, DJ 2023, 'IgE receptor of mast cells signals mediator release and inflammation via adaptor protein 14-3-3ζ', Journal of Allergy and Clinical Immunology, vol. 152, no. 3, pp. 725-735. Open access 5 5 2
2022	Edwards, AB, Mastaglia, FL, Knuckey, NW, Yip, KH & Meloni, B 2022, 'Assessment of the safety of the cationic arginine-rich peptides (CARPs) poly-arginine-18 (R18 and R18D) in ex vivo models of mast cell degranulation and red blood cell hemolysis', Biochemistry and Biophysics Reports, vol. 31, article no. 101305. Open access 2 2
2022	Wang, H, Tumes, DJ, Hercus, TR, Yip, K, Aloe, C, Vlahos, R, Lopez, AF, Wilson, N, Owczarek, CM & Bozinovski, S 2022, 'Blocking the human common beta subunit of the GM-CSF, IL-5 and IL-3 receptors markedly reduces hyperinflammation in ARDS models', Cell Death and Disease, vol. 13, no. 2, article no. 137, pp. 1-11. Open access 24 20 6
2022	Yip, KH, McKenzie, D, Ramshaw, HS, Chao, J, McClure, BJ, Pant, H, Grimbaldeston, MA, Hercus, TR, Lopez, AF & Tumes, DJ and 12 other authors 2022, 'Targeting the human β𝒸 receptor inhibits contact dermatitis in a transgenic mouse model', Journal of Investigative Dermatology, vol. 142, no. 4, pp 1103-1113.e11. Open access 6 4 1
2021	Cildir, G, Yip, KH, Pant, H, Tergaonkar, V, Lopez, AF & Tumes, DJ 2021, 'Understanding mast cell heterogeneity at single cell resolution', Trends in Immunology, vol. 42, no. 6, pp. 523-535. Open access 31 29 6
2021	De Silva, AP, Schembri, MA, Sarah, AH, Chao, J, Yip, KH, Cildir, G, Lopez, A, Tumes, DJ & Pant, H 2021, 'Short-term oral steroids significantly improves chronic rhinosinusitis without nasal polyps', The Laryngoscope, vol. 131, no. 10, pp. E2618-E2626. 5 5 3
2020	Yip, KH, Wilson, NJ, Pant, H, Brown, CL, Busfield, S, Ng, M, Alhamdoosh, M, Woodman, N, Schembri, M, Tumes, DJ, Vairo, G, Lopez, AF, Nash, AD, Wilson, MJ, Grimbaldeston, MA & Owczarek, CM 2020, 'Anti‐βc mAb CSL311 inhibits human nasal polyp pathophysiology in a humanized mouse xenograft model', Allergy: European Journal of Allergy and Clinical Immunology, vol. 75, no. 2, pp. 475-478. 9 7 6
2019	Cildir, G, Toubia, J, Yip, KH, Zhou, M, Pant, H, Hissaria, P, Zhang, J, Hong, W, Robinson, N, Grimbaldeston, MA, Lopez, AF & Tergaonkar, V 2019, 'Genome-wide analyses of chromatin state in human mast cells reveal molecular drivers and mediators of allergic and inflammatory diseases', Immunity, vol. 51, no. 5, pp. 949-965.e6. Open access 47 47 12
2019	Tumes, D, Hirahara, K, Papadopoulos, M, Shinoda, K, Onodera, A, Kumagai, J, Yip, KH, Pant, H, Kokubo, K, Kiuchi, M, Aoki, A, Obata-Ninomiya, K, Tokoyoda, K, Endo, Y, Kimura, MY & Nakayama, T 2019, 'Ezh2 controls development of natural killer T cells, which cause spontaneous asthma-like pathology', Journal of Allergy and Clinical Immunology, vol. 144, no. 2, pp. 549-560.e 10. Open access 30 27 3
2019	Yip, KH, Papadopoulos, M, Pant, H & Tumes, DJ 2019, 'The role of invariant T cells in inflammation of the skin and airways', Seminars in Immunopathology, vol. 41, no. 3, pp. 401-410. Open access 15 15 2
2016	Yip, K-H, Kolesnikoff, N, Hauschild, N, Biggs, L, Lopez, AF, Galli, SJ, Kumar, S & Grimbaldeston, MA 2016, 'The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation', Nature Communications, vol. 7, article no.13198, pp. 1-14. Open access 27 27
2014	Yip, K-H, Kolesnikoff, N, Yu, C, Hauschild, N, Taing, H, Biggs, L, Goltzman, D, Gregory, PA, Anderson, PH, Samuel, MS, Galli, SJ, Lopez, A & Grimbaldeston, MA 2014, 'Mechanisms of vitamin D₃ metabolite repression of IgE-dependent mast cell activation', Journal of Allergy and Clinical Immunology, vol. 133, no. 5, pp. 1356-1364. Open access 100 88
2013	Roediger, B, Kyle, R, Yip, KH, Sumaria, N, Guy, T V, Kim, BS, Mitchell, AJ, Tay, SS, Jain, R, Forbes-Blom, E, Chen, X, Tong, PL, Bolton, HA, Artis, D, Paul, WE, de St Groth, BF, Grimbaldeston, MA, Le Gros, G & Weninger, W 2013, 'Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells', Nature Immunology, vol. 14, no. 6, pp. 564-573. Open access 415 387
2011	Yip, K, Lau, H & Wise, H 2011, 'Reciprocal modulation of anti-IgE induced histamine release from human mast cells by A₁ and A₂B adenosine receptors', British Journal of Pharmacology, vol. 164, no. 2b, pp. 807-819. Open access 17 16
2010	Yip, KH, Huang, Y, Leung, FP & Lau, HY 2010, 'Cyclic guanosine monophosphate dependent pathway contributes to human mast cell inhibitory actions of the nitric oxide donor, diethylamine NONOate', European Journal of Pharmacology, vol. 632, no. 1-3, pp. 86-92. 7 7
2009	Yip, K, Leung, F, Huang, Y & Lau, H 2009, 'Inhibition of anti-IgE mediated human mast cell activation by NO donors is dependent on their NO release kinetics', British Journal of Pharmacology, vol. 156 no. 8, pp. 1279-1286. Open access 5 5
2009	Yip, K, Wong, L & Lau, H 2009, 'Adenosine: roles of different receptor subtypes in mediating histamine release from human and rodent mast cells', Inflammation Research, vol. 58 no. s1, pp. s17-s19. 8
2008	Yip, K-H, Lau, H, Waye, MM & Huang, Y-f 2008, 'Induction of nitric oxide synthases in primary human cultured mast cells by IgE and proinflammatory cytokines', International Immunopharmacology, vol. 8 no. 5, pp. 764-768. 15

Research

Patents

Details	Registry	Status
Methods for treating inflammatory skin conditions Owczarek, Catherine; Lopez, Angel; Yip, Kwok Ho; Tumes, Damon	WO	Granted

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
A-Star, Institute of Molecular and Cell Biology	SINGAPORE
Centenary Institute	AUSTRALIA
Chiba University	JAPAN
CSL Limited	AUSTRALIA
Deutsches Rheuma-Forschungszentrum	GERMANY
Genentech, Inc.	UNITED STATES
Malaghan Institute of Medical Research	NEW ZEALAND
McGill University	CANADA
National Institute of Allergic Disease	UNITED STATES
National Kaohsiung University of Applied Sciences	TAIWAN
Perelman School of Medicine Philadelphia	UNITED STATES
Queen Elizabeth II Medical Centre	AUSTRALIA
RMIT University	AUSTRALIA
Royal Adelaide Hospital	AUSTRALIA
Royal Prince Alfred Hospital	AUSTRALIA
Royal Victorian Eye and Ear Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
Stanford University	UNITED STATES
Texas A and M University	UNITED STATES
The Chinese University of Hong Kong (CUHK)	CHINA
University of Adelaide	AUSTRALIA
University of Melbourne	AUSTRALIA
University of Newcastle	AUSTRALIA
University of Pennsylvania	UNITED STATES
University of South Australia	AUSTRALIA
University of Sydney	AUSTRALIA
University of Western Australia	AUSTRALIA
Women's and Children's Hospital	AUSTRALIA

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
Deciphering how airway epithelial programming and inflammation cause chronic allergic airways disease	Current

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Dr Dave Yip

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Journal Articles

Patents

External engagement & recognition

Collaborations

Collaborations

Teaching & student supervision

Courses and programs

Research degree supervision

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