Associate Professor David Ross

Adjunct Associate Professor Centre for Cancer Biology

City West Campus ()
tel +61 8 830 27560

email David.Ross@unisa.edu.au

Research

Research focus

Clinical Sciences
Biochemistry and Cell Biology
Oncology and Carcinogenesis
Cardiovascular Medicine and Haematology
Pharmacology and Pharmaceutical Sciences

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included.

Open access indicates that an output is open access.

Chapters

Year	Output
2023	Shanmuganathan, N & Ross, DM 2023, 'Treatment-free remission in chronic myeloid leukemia', in H Gill & Y Kwong (eds), Pathogenesis and Treatment of Leukemia, Springer, Singapore, ch. 49, pp. 635-647.

Journal Articles

Year	Output
2025	Kan, WL, Weekley, CM, Nero, TL, Hercus, TR, Yip, KH, Tumes, DJ, Woodcock, JM, Ross, DM, Thomas, D, Terán, D, Owczarek, CM, Liu, NW, Martelotto, LG, Polo, JM, Pant, H, Tvorogov, D, Lopez, AF & Parker, MW 2025, 'The β common cytokine receptor family reveals new functional paradigms from structural complexities', Immunological Reviews, vol. 329, no. 1, pp. 1-25. Open access 1 3 1
2024	Lim, J, Ross, DM, Brown, AL, Scott, HS & Hahn, CN 2024, 'Germline genetic variants that predispose to myeloproliferative neoplasms and hereditary myeloproliferative phenotypes', Leukemia Research, vol. 146, article no. 107566, pp. 1-10. Open access 2 2
2024	Lim, K, Kan, WL, Nair, PC, Kutyna, M, Lopez, AF, Hercus, T, Ross, DM, Lane, S, Fong, CY, Brown, A, Yong, A, Yeung, D, Hughes, T, Hiwase, D & Thomas, D 2024, 'CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: implications for targeting', PLoS One, vol. 19, no. 9, pp. 1-19. Open access 1
2024	Nguyen, TM, Joyce, P, Ross, DM, Bremmell, K, Jambhrunkar, M, Wong, SS & Prestidge, CA 2024, 'Combating acute myeloid leukemia via sphingosine kinase 1 inhibitor-nanomedicine combination therapy with cytarabine or venetoclax', Pharmaceutics, vol. 16, no. 2, article no. 209, pp. 1-16. Open access 7 5
2024	Nwosu, GO, Ross, DM, Powell, JA & Pitson, SM 2024, 'Venetoclax therapy and emerging resistance mechanisms in acute myeloid leukaemia', Cell Death and Disease, vol. 15, no. 6, article no. 413, pp. 1-11. Open access 27 24 1
2024	Venugopal, P, Arts, P, Fox, LC, Simons, A, Ross, DM, Frank, MS, Ha, TT, Jackson, MR, Arriola-Martinez, L, Kenyon, R, Brown, AL, Hahn, CN & Scott, HS 2024, 'Unraveling facets of MECOM-associated syndrome: somatic genetic rescue, clonal hematopoiesis, and phenotype expansion', Blood Advances, vol. 8, no. 13, pp. 3437-3443. Open access 4 1 9
2024	Zerella, JR, Homan, CC, Arts, P, Lin, X, Spinelli, SJ, Venugopal, P, Babic, M, Brautigan, PJ, Arriola-Martinez, L, Parker, WT, Branford, S, Ross, DM, Brown, AL, Scott, HS & Hahn, CN 37 other authors and 1 consortium 2024, 'Germ line ERG haploinsufficiency defines a new syndrome with cytopenia and hematological malignancy predisposition', Blood, vol. 144, no. 17, pp. 1765-1780. Open access 8 7 23
2023	Nair, PC, Piehler, J, Tvorogov, D, Ross, DM, Lopez, AF, Gotlib, J & Thomas, D 2023, 'Next-generation JAK2 inhibitors for the treatment of myeloproliferative neoplasms: lessons from structure-based drug discovery approaches', BLOOD CANCER DISCOVERY, vol. 4, no. 5, pp. 352-364. 15 13 8
2023	Nguyen, TM, Jambhrunkar, M, Wong, SS, Ross, DM, Joyce, P, Finnie, JW, Manavis, J, Bremmell, K, Pitman, MR & Prestidge, CA 2023, 'Targeting acute myeloid leukemia using sphingosine kinase 1 inhibitor-loaded liposomes', Molecular Pharmaceutics, vol. 20, no. 8, pp. 3937-3946. 8 7
2023	Ross, DM, Liang, HPH, Iqra, Z, Whittaker, S, Tan, CW, Dale, BJ & Chen, VM 2023, 'Platelets from patients with myeloproliferative neoplasms have increased numbers of mitochondria that are hypersensitive to depolarization by thrombin', Scientific Reports, vol. 13, no. 1, article no. 9172, pp. 1-14. Open access 11 9
2023	Samaraweera, SE, Geukens, T, Casolari, DA, Nguyen, T, Sun, C, Bailey, S, Moore, S, Feng, J, Schreiber, AW, Parker, WT, Brown, AL, Butcher, C, Bardy, PG, Osborn, M, Scott, HS, Talaulikar, D, Grove, CS, Hahn, CN, D'Andrea, RJ & Ross, DM 2023, 'Novel modes of MPL activation in triple-negative myeloproliferative neoplasms', Pathology, vol. 55, no. 1, pp. 77-85. Open access 2 2 1
2023	Shanmuganathan, N, Wadham, C, Shahrin, NH, Feng, J, Thomson, D, Wang, P, Kok, CH, King, RM, Kenyon, RR, Lin, M, Ross, DM, Yeung, DT, Scott, HS, Schreiber, AW & Branford, S and 9 other authors 2023, 'Impact of additional genetic abnormalities at diagnosis of chronic myeloid leukemia for first-line imatinib-treated patients receiving proactive treatment intervention', Haematologica: The Hematology Journal, vol. 108, no. 9, pp. 2380-2395. Open access 18 18 13
2023	Sharplin, K, Proudman, W, Chhetri, R, Tran, ENH, Choong, J, Kutyna, M, Selby, P, Sapio, A, Friel, O, Khanna, S, Singhal, D, Damin, M, Ross, D, Yeung, D, Thomas, D, Kok, CH & Hiwase, D 2023, 'A personalized risk model for azacitidine outcome in myelodysplastic syndrome and other myeloid neoplasms identified by machine learning model utilizing real-world data', Cancers, vol. 15, no. 16, article no. 4019, pp. 1-14. Open access 3 3
2022	Bassal, MA, Samaraweera, SE, Lim, K, Bernard, BA, Bailey, S, Toubia, J, Nguyen, T, Maung, KZY, Casolari, DA, Iarossi, DG, Powell, J, Pitson, S, Brown, AL, Robinson, N, Ross, DM, Gonda, TJ & D'Andrea, RJ and 10 other authors 2022, 'Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia', Nature Communications, vol. 13, article no. 2614, pp. 1-12. Open access 18 18 8
2022	Cameron, JK, Fritschi, L, Ross, DM, Anderson, LA & Baade, P 2022, 'Spatial disparities in the reported incidence and survival of myeloproliferative neoplasms in Australia', Pathology, vol. 54, no. 3, pp. 328-335. 3
2022	Lewis, AC, Pope, VS, Tea, MN, Li, M, Nwosu, GO, Nguyen, TM, Wallington-Beddoe, CT, Moretti, PA, Costabile, M, Ali, SR, Dredge, BK, Bert, AG, Goodall, GJ, Brown, AL, D'Andrea, R, Robinson, N, Pitman, MR, Ross, DM, Gliddon, BL, Powell, JA & Pitson, SM and 5 other authors 2022, 'Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia', Blood, vol. 139, no. 26, pp. 3737-3751. Open access 37 32 73
2022	Perram, J, Ross, DM, McLornan, D, Gowin, K, Kröger, N, Gupta, V, Lewis, C, Gagelmann, N & Hamad, N 2022, 'Innovative strategies to improve hematopoietic stem cell transplant outcomes in myelofibrosis', American Journal of Hematology, vol. 97, no. 11, pp. 1464-1477. Open access 12 12
2022	Ross, DM 2022, 'Iron chelation for myelofibrosis-related anaemia during treatment with a Janus kinase inhibitor', British Journal of Haematology, vol. 197, no. 2, pp. 135-136. Open access
2022	Tvorogov, D, Thompson-Peach, CA, Foßelteder, J, Dottore, M, Stomski, F, Onnesha, SA, Lim, K, Moretti, PA, Pitson, SM, Ross, DM, Reinisch, A, Thomas, D & Lopez, AF 2022, 'Targeting human CALR-mutated MPN progenitors with a neoepitope-directed monoclonal antibody', EMBO Reports, vol. 23, no. 4, article no. e52904. Open access 22 22 12
2021	McCaughan, G, Di Ciaccio, P, Ananda-Rajah, M, Gilroy, N, Ross, DM & Hamad, N 2021, 'COVID-19 vaccination in haematology patients: an Australian and New Zealand consensus position statement', Internal Medicine Journal, vol. 51, no. 5, pp. 763-768. Open access 13 13
2021	Ross, DM, Babon, JJ, Tvorogov, D & Thomas, D 2021, 'Persistence of myelofibrosis treated with ruxolitinib: biology and clinical implications', Haematologica: The Hematology Journal, vol. 106, no. 5, pp. 1244-1253. Open access 23 22 25
2021	Ross, DM, Thomson, C, Hamad, N, Lane, SW, Manos, K, Grigg, AP, Guo, B, Erber, WN, Scott, A, Viiala, N, Chee, L, Latimer, M, Tate, C, Grove, C, Perkins, AC & Blombery, P 2021, 'Myeloid somatic mutation panel testing in myeloproliferative neoplasms', Pathology, vol. 53, no. 3, pp. 339-348. Open access 19 16
2021	Samaraweera, SE, Wang, PP, Li, KL, Casolari, DA, Feng, J, Maung, KZY, Scott, HS, Schreiber, AW, Brown, AL, Ross, DM, Gonda, TJ, Hahn, CN & D'Andrea, RJ and 13 other authors 2021, 'Childhood acute myeloid leukemia shows a high level of germline predisposition', Blood, vol. 138, no. 22, pp. 2293-2298. Open access 11 9 39
2021	Shanmuganathan, N, Pagani, IS, Ross, DM, Park, S, Yong, AS, Braley, J, Altamura, H, Hiwase, DK, Yeung, DT, Kim, D-W, Branford, S & Hughes, TP 2021, 'Early BCR-ABL1 kinetics are predictive of subsequent achievement of treatment-free remission in chronic myeloid leukemia', Blood, vol. 137, no. 9, pp. 1196-1207. Open access 70 62
2020	Pagani, IS, Dang, P, Saunders, VA, Braley, J, Thieleke, A, Branford, S, Hughes, TP & Ross, DM 2020, 'Clinical utility of genomic DNA Q-PCR for the monitoring of a patient with atypical e19a2 BCR-ABL1 transcripts in chronic myeloid leukemia', Leukemia and Lymphoma, vol. 61, no. 10, pp. 2527-2529. Open access 9 6
2020	Pagani, IS, Dang, P, Saunders, VA, Grose, R, Shanmuganathan, N, Kok, CH, Carne, L, Rwodzi, Z, Watts, S, McLean, J, Braley, J, Altamura, H, Yeung, DT, Branford, S, Yong, AS, White, DL, Hughes, TP & Ross, DM 2020, 'Lineage of measurable residual disease in patients with chronic myeloid leukemia in treatment-free remission', Leukemia, vol. 34, pp. 1052-1061. Open access 42 41
2019	Forsyth, CJ, Chan, W-H, Grigg, AP, Cook, NC, Lane, SW, Burbury, KL, Perkins, AC & Ross, DM 2019, 'Recommendations for the use of pegylated interferon‐α in the treatment of classical myeloproliferative neoplasms', Internal Medicine Journal, vol. 49, no. 8, pp. 948-954. 7 8
2019	Ross, DM, Pagani, IS, Irani, YD, Clarson, J, Leclercq, T, Dang, P, McLean, J, Saunders, VA, Carne, L, Reynolds, J, Ritchie, DS, White, DL, Branford, S, Hughes, TP & Yong, AS 2019, 'Lenalidomide maintenance treatment after imatinib discontinuation: results of a phase 1 clinical trial in chronic myeloid leukaemia', British Journal of Haematology, vol. 186, no. 3, pp. e56-e60. Open access 13 12
2019	Shanmuganathan, N, Braley, JA, Yong, AS, Hiwase, DK, Yeung, DT, Ross, DM, Hughes, TP & Branford, S 2019, 'Modeling the safe minimum frequency of molecular monitoring for CML patients attempting treatment-free remission', Blood, vol. 134, no. 1, pp. 85-89. Open access 27 25
2018	Pagani, IS, Dang, P, Kommers, IO, Goyne, JM, Nicola, M, Saunders, VA, Braley, J, White, DL, Yeung, DT, Branford, S, Hughes, TP & Ross, DM 2018, 'BCR-ABL1 genomic DNA PCR response kinetics during first-line imatinib treatment of chronic myeloid leukemia', Haematologica: The Hematology Journal, vol. 103, no. 12, pp. 2026-2032. Open access 36 28
2018	Ross, DM, Pagani, IS, Shanmuganathan, N, Kok, CH, White, DL, Branford, S & Hughes, TP and 11 other authors and 1 constourium 2018, 'Long-term treatment-free remission of chronic myeloid leukemia with falling levels of residual leukemic cells', Leukemia, vol. 32, no. 12, pp. 2572-2579. 67 62
2018	Tvorogov, D, Thomas, D, Liau, NP, Dottore, M, Barry, EF, Lathi, M, Kan, WL, Hercus, TR, Stomski, F, Hughes, TP, Tergaonkar, V, Parker, MW, Ross, DM, Majeti, R, Babon, JJ & Lopez, AF 2018, 'Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis', Science Advances, vol. 4, no. 11, article no. eaat3834, pp. 1-13. Open access 45 46 3
2017	Pagani, IS, Kok, CH, Saunders, VA, Van der Hoek, MB, Heatley, SL, Schwarer, AP, Hahn, CN, Hughes, TP, White, DL & Ross, DM 2017, 'A method for next-generation sequencing of paired diagnostic and remission samples to detect mitochondrial DNA mutations associated with leukemia', Journal of Molecular Diagnostics, vol. 19, no. 5, pp. 711-721. Open access 6 5

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Auckland City Hospital	NEW ZEALAND
Austin Health	AUSTRALIA
Austin Hospital	AUSTRALIA
Australasian Leukaemia and Lymphoma Group	AUSTRALIA
Australian National University	AUSTRALIA
Banyule Community Health	AUSTRALIA
Box Hill Hospital	AUSTRALIA
Canberra Hospital	AUSTRALIA
Cancer Council Queensland	AUSTRALIA
Catholic University of Korea	KOREA, REPUBLIC OF (SOUTH)
Concord Repatriation General Hospital	AUSTRALIA
CSL Limited	AUSTRALIA
Curtin University	AUSTRALIA
Gosford Hospital	AUSTRALIA
Griffith University	AUSTRALIA
Harvard University	UNITED STATES
Hudson Institute of Medical Research	AUSTRALIA
Medical University of Graz	AUSTRIA
Monash University	AUSTRALIA
Osnabrueck University	GERMANY
Pathwest Laboratory Medicine	AUSTRALIA
Peter MacCallum Cancer Centre	AUSTRALIA
QIMR Berghofer Medical Research Institute	AUSTRALIA
Queen's University	CANADA
Queensland University of Technology	AUSTRALIA
Radboud Institute for Molecular Life Sciences	NETHERLANDS
Royal Adelaide Hospital	AUSTRALIA
Royal Brisbane and Women's Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
Sir Charles Gardiner Hospital	AUSTRALIA
South Australian Health and Medical and Research Institute (SAHMRI)	AUSTRALIA
South Australian Health and Medical Institute	AUSTRALIA
St Vincent’s Hospital	AUSTRALIA
St Vincent's Hospital	AUSTRALIA
Stanford University	UNITED STATES
The Alfred Hospital	AUSTRALIA
University College London Hospitals NHS Foundation Trust	UNITED KINGDOM
University Medical Center Hamburg-Eppendorf	GERMANY
University of Aberdeen	UNITED KINGDOM
University of Adelaide	AUSTRALIA
University of Arizona	UNITED STATES
University of Melbourne	AUSTRALIA
University of New South Wales	AUSTRALIA
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Sydney	AUSTRALIA
University of Toronto	CANADA
University of Western Australia	AUSTRALIA
VU University Medical Center	NETHERLANDS
Walter and Eliza Hall Institute of Medical Research	AUSTRALIA
Westmead Hospital	AUSTRALIA
Wyong Public Hospital	AUSTRALIA

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Associate Professor David Ross

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Research

Research focus

Projects

Outputs

Chapters

Journal Articles

External engagement & recognition

Collaborations

Collaborations

Gallery