Professor David Waugh

Pro Vice Chancellor: Health and Medical Research and Engagement Chancellery and Council Services

email David.Waugh@unisa.edu.au

Alternative contact

Research Degree Supervisor

About me

Professor David Waugh is the Inaugural Pro-Vice Chancellor for Health and Medical Research and Engagement at University of South Australia, a role focused on developing inter-disciplinary and impactful research programmes that provide transformative solutions to inform improved patient outcomes and future healthcare practice. He was formerly the Head of School for Biomedical Sciences at Queensland University of Technology and prior to emigrating to Australia, he served as Director of the Patrick G Johnston Centre for Cancer Research at Queen’s University and the CRUK Belfast Cancer Centre, developing an ecosystem that integrated academic discovery science with entrepreneurial biotech research and development and finally... Read more

UniSA Chancellery and Council Services

Home to the senior executive and facilitating communication between senior management, governing bodies and the University.

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Orcid
Scopus

Research

Research focus

Biochemistry and Cell Biology
Oncology and Carcinogenesis
Biomedical Engineering
Clinical Sciences
Medical Biotechnology

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Chapters

Year	Output
2018	Armstrong, CW, Lyubomska, O, LaBonte, MJ & Waugh, DJ 2018, 'Protocols for studies on genetically engineered mouse models in prostate cancer', in Zoram Lulig (ed.), Prostate Cancer, Springer, US, ch. 11, pp. 195-206.

Journal Articles

Year	Output
2024	Bessot, A, Medeiros Savi, F, Gunter, J, Mendhi, J, Amini, S, Waugh, D, McGovern, J, Hutmacher, DW & Bock, N 2024, 'Humanized in vivo bone tissue engineering: in vitro preculture conditions control the structural, cellular, and matrix composition of humanized bone organs', Advanced Healthcare Materials, online, pp. 1-22. Open access 1 1
2024	Nturubika, BD-D, Logan, J, Johnson, IRD, Moore, C, Li, KL, Tang, J, Lam, G, Parkinson-Lawrence, E, Williams, DB, Chakiris, J, Hindes, M, Brooks, RD, Gregory, P, Waugh, DJJ & Brooks, DA and 7other authors 2024, 'Components of the endosome-lysosome vesicular machinery as drivers of the metastatic cascade in prostate cancer', Cancers, vol. 17, no. 1, article no. 43, pp. 1-31. Open access
2023	Bessot, A, Gunter, J, Waugh, D, Clements, JA, Hutmacher, DW, McGovern, J & Bock, N 2023, 'GelMA and biomimetic culture allow the engineering of mineralized, adipose, and tumor tissue human microenvironments for the study of advanced prostate cancer in vitro and in vivo', Advanced Healthcare Materials, vol. 12, no. 14, article no. 2201701. Open access 16 15 6
2023	Guo, C, Sharp, A, Gurel, B, Crespo, M, Waugh, D & de Bono, JS and 43 other authors 2023, 'Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance', Nature, vol. 623, no. 7989, pp. 1053-1061. Open access 32 28 257
2021	Amoroso, F, Glass, K, Singh, R, Liberal, F, Steele, RE, Maguire, S, Tarapore, R, Allen, JE, Van Schaeybroeck, S, Butterworth, KT, Prise, K, O'Sullivan, JM, Jain, S, Waugh, DJ & Mills, IG 2021, 'Modulating the unfolded protein response with ONC201 to impact on radiation response in prostate cancer cells', Scientific Reports, vol. 11, no. 1, article no. 4252, pp. 1-16. Open access 8 8 12
2021	Hanna, C, Dunne, VL, Walker, SM, Butterworth, KT, McCabe, N, Waugh, DJ, Kennedy, RD & Prise, KM 2021, 'ATM kinase inhibition preferentially sensitises pten-deficient prostate tumour cells to ionising radiation', Cancers, vol. 13, no. 1, article no. 79, pp. 1-17. Open access 5 5 3
2020	Murphy, RG, Roddy, AC, Srivastava, S, Baena, E, Waugh, DJ, O Sullivan, JM, McArt, DG, Jain, S & LaBonte, MJ 2020, 'Prostate cancer heterogeneity assessment with multi-regional sampling and alignment-free methods', NAR Genomics and Bioinformatics, vol. 2, no. 3, article no. lqaa062, pp. 1-7. Open access 8
2019	Di Mitri, D, Mirenda, M, Vasilevska, J, Calcinotto, A, Waugh, D & Alimonti, A and 19 other authors 2019, 'Re-education of tumor-associated macrophages by CXCR2 blockade drives senescence and tumor inhibition in advanced prostate cancer', Cell Reports, vol. 28, no. 8, pp. 2156-2168.e5. Open access 148 146 30
2019	Gilmore, AR, Alderdice, M, Savage, K I, O Reilly, PG, Roddy, AC, Dunne, PD, Lawler, M, McDade, SS, Waugh, DJ & McArt, DG 2019, 'ACE: A workbench using evolutionary genetic algorithms for analyzing association in TCGA', Cancer Research, vol. 79, no. 8, pp. 2072-2075. 6 6
2018	Jain, S, Lyons, C, Walker, S, McQuaid, S & Waugh, D 2018, 'Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy', Annals of Oncology, vol. 29, no. 1, pp. 215-222. Open access 71 73 63
2018	McCann, C, Crawford, N, Majkut, J, Holohan, C, Armstrong, CW, Maxwell, PJ, Ong, CW, LaBonte, MJ, McDade, SS, Waugh, DJ & Longley, DB 2018, 'Cytoplasmic FLIP(S) and nuclear FLIP(L) mediate resistance of castrate-resistant prostate cancer to apoptosis induced by IAP antagonists', Cell Death and Disease, vol. 9, no. 11, article no. 1081, pp. 1-13. Open access 12 12 1
2018	Ong, CW, Maxwell, P, Alvi, MA, McQuaid, S, Waugh, D, Mills, I & Salto Tellez, M 2018, 'A gene signature associated with PTEN activation defines good prognosis intermediate risk prostate cancer cases', Journal of Pathology: Clinical Research, vol. 4, no. 2, pp. 103-113. Open access 19 19 1
2018	Sumanasuriya, S, Omlin, A, Armstrong, A, Attard, G, Chi, KN, Bevan, CL, Shibakawa, A, IJzerman, MJ, De Laere, B, Lolkema, M, Lorente, D, Luo, J, Mehra, N, Olmos, D, Scher, H, Soule, H, Stoecklein, NH, Terstappen, LW, Waugh, D & de Bono, JS 2018, 'Consensus Statement on Circulating Biomarkers for Advanced Prostate Cancer', European Urology Oncology, vol. 1, no. 2, pp. 151-159. Open access 29 27 25
2017	Walker, SM, Knight, LA, McCavigan, AM, Logan, GE, Waugh, DJ & Kennedy, RD and 21 other authors 2017, 'Molecular subgroup of primary prostate cancer presenting with metastatic biology', European Urology. Open access 26 23 33
2016	Armstrong, CW, Maxwell, PJ, Ong, CW, Redmond, KM, McCann, C, Neisen, J, Ward, GA, Chessari, G, Johnson, C, Crawford, NT, LaBonte, MJ, Prise, KM, Robson, T, Salto Tellez, M, Longley, DB & Waugh, DJ 2016, 'PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy', Oncotarget, vol. 7, no. 7, pp. 7885-7898. Open access 30 29 1
2016	Bingham, V, Ong, CW, James, J, Maxwell, P, Waugh, D, Salto Tellez, M & McQuaid, S 2016, 'PTEN mRNA detection by chromogenic, RNA in situ technologies: a reliable alternative to PTEN immunohistochemistry', Human Pathology, vol. 47, no. 1, pp. 95-103. 17 18 2
2016	Dunne, PD, McArt, DG, Bradley, CA, O'Reilly, PG, Barrett, HL, Cummins, R, O'Grady, T, Arthur, K, Loughrey, MB, Allen, WL, McDade, SS, Waugh, DJ, Hamilton, PW, Longley, DB, Kay, EW, Johnston, PG, Lawler, M, Salto Tellez, M & Van Schaeybroeck, S 2016, 'Challenging the cancer molecular stratification dogma: intratumoral heterogeneity undermines consensus molecular subtypes and potential diagnostic value in colorectal cancer', Clinical Cancer Research, vol. 22, no. 16, pp. 4095-4104. Open access 124 117 9
2015	McFarlane, S, Coulter, JA, Tibbits, P, O'Grady, A, McFarlane, C, Montgomery, N, Hill, A, McCarthy, HO, Young, LS, Kay, EW, Isacke, CM & Waugh, DJ 2015, 'CD44 increases the efficiency of distant metastasis of breast cancer', Oncotarget, vol. 6, no. 13, pp. 11465-11476. Open access 90 83
2015	McFarlane, S, McFarlane, C, Montgomery, N, Hill, A & Waugh, DJ 2015, 'CD44-mediated activation of α5β1-integrin, cortactin and paxillin signaling underpins adhesion of basal-like breast cancer cells to endothelium and fibronectin-enriched matrices', Oncotarget, vol. 6, no. 34, pp. 36762-36773. Open access 48 48 1
2015	Ong, CW, Chong, PY, McArt, DG, Chan, JY, Tan, HT, Kumar, AP, Chung, MC, Clement, MV, Soong, R, Van Schaeybroeck, S, Waugh, DJ, Johnston, PG, Dunne, PD & Salto Tellez, M 2015, 'The prognostic value of the stem-like group in colorectal cancer using a panel of immunohistochemistry markers', Oncotarget, vol. 6, no. 14, pp. 12763-12773. Open access 18

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Almac (United Kingdom)	UNITED KINGDOM
Astex Pharmaceuticals	UNITED STATES
BC Cancer Agency	CANADA
Beaumont Hospital	IRELAND
Cantonal Hospital, St. Gallen	SWITZERLAND
Duke University	UNITED STATES
Erasmus MC Cancer Institute	NETHERLANDS
Heinrich-Heine University Medical Center	GERMANY
Hospital Universitari i Politcnic La Fe	SPAIN
Imperial College of Science, Technology and Medicine	UNITED KINGDOM
Institute of Cancer Research	UNITED KINGDOM
Institute of Oncology Research	SWITZERLAND
Istituti di Ricovero e Cura a Carattere Scientifico	ITALY
Johns Hopkins University	UNITED STATES
Memorial Sloan Kettering Cancer Centre	UNITED STATES
National Cancer Centre Singapore	SINGAPORE
National University of Singapore	SINGAPORE
Oncoceutics (United States)	UNITED STATES
Prostate Cancer Foundation	UNITED STATES
Queen's University Belfast	UNITED KINGDOM
Queensland University of Technology	AUSTRALIA
Radboud University Nijmegen Medical Centre	NETHERLANDS
Royal Marsden Hospital	UNITED KINGDOM
Spanish National Cancer Research Centre	SPAIN
University of Antwerp	BELGIUM
University of Manchester	UNITED KINGDOM
University of Oxford	UNITED KINGDOM
University of Padua	ITALY
University of South Australia	AUSTRALIA
University of Twente	NETHERLANDS

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Professor David Waugh

Alternative contact

Alternative contact details

About me

About me

UniSA Chancellery and Council Services

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Chapters

Journal Articles

External engagement & recognition

Collaborations

Collaborations

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