Dr Donna Denton has a research program at the Centre for Cancer Biology. Her research interests are using Drosophila as a model to study complex biological processes that when dysregulated result in diseases. The process of autophagy is critical for normal physiology and its deregulation is a hallmark of many human disorders. Her seminal findings discovered a mode of cell death mediated by autophagy. Her current research is focused on dissecting out the mechanisms regulating autophagy and cell death during Drosophila development. As deregulation of autophagy occurs in various human pathologies, including cancer and neurodegeneration, her research will provide new knowledge applicable to human physiology and disease.
About me
Dr Donna Denton has a research program at the Centre for Cancer Biology. Her research interests are using Drosophila as a model to study complex biological processes that when dysregulated result in diseases. The process of autophagy is critical for normal physiology and its deregulation is a hallmark of many human disorders. Her seminal findings discovered a mode of cell death mediated by autophagy. Her current research is focused on dissecting out the mechanisms regulating autophagy and cell death during Drosophila development. As deregulation of autophagy occurs in various human pathologies, including cancer and neurodegeneration, her research will provide new knowledge applicable to human physiology and disease.
About me
PhD: Molecular Biosciences / Cell Development The University of Adelaide
Bachelor of Science (Honours) The University of Adelaide
Bachelor of Science The University of Adelaide
Research
Excludes commercial-in-confidence projects.
Hormone dependent autophagy and growth signalling in developmental cell death, NHMRC - Project Grant, 01/01/2017 - 31/12/2019
Hormone-dependent autophagy and growth signalling in developmental cell death.
NHMRC - Project Grant, 01/01/2017 - 31/12/2019
Research
Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus
Open access indicates that an output is open access.
| Year | Output |
|---|---|
| 2020 |
4
3
4
|
| 2019 |
Open access
376
327
18
|
| 2019 |
Open access
36
36
4
|
| 2009 |
Open access
300
285
|
| Year | Output |
|---|---|
| 2023 |
|
| 2021 |
9
8
18
|
| 2021 |
14
18
18
|
| 2021 |
6
5
2
|
| 2020 |
4
3
4
|
| 2019 |
Open access
376
327
18
|
| 2019 |
Open access
3
5
5
|
| 2019 |
Open access
36
36
4
|
| 2019 |
6
6
4
|
| 2019 |
Open access
30
24
5
|
| 2018 |
Open access
17
19
10
|
| 2017 |
10
10
|
| 2016 |
Open access
15
13
1
|
| 2015 |
1
6
|
| 2015 |
4
|
| 2015 |
10
|
| 2015 |
Open access
11
|
| 2015 |
Open access
2
1
|
| 2015 |
9
1
|
| 2015 |
137
136
2
|
| 2015 |
Open access
32
30
1
|
| 2015 |
Open access
16
44
13
|
| 2013 |
Open access
57
56
|
| 2013 |
Open access
47
42
|
| 2012 |
Open access
58
52
|
| 2012 |
Open access
321
309
|
| 2012 |
Open access
2825
3054
|
| 2011 |
Open access
18
18
|
| 2010 |
Open access
53
49
|
| 2009 |
Open access
300
285
|
| 2008 |
Open access
25
24
|
| 2008 |
29
28
|
Research
External engagement & recognition
| Organisation | Country |
|---|---|
| Federal University of Sao Carlos | BRAZIL |
| Flinders University | AUSTRALIA |
| Georgetown University | UNITED STATES |
| Hebrew University | MEXICO |
| Pfizer Worldwide Research and Development | UNITED STATES |
| SA Pathology | AUSTRALIA |
| South Australian Health and Medical Research Institute (SAHMRI) | AUSTRALIA |
| The Institut Pasteur (AKA L'Institut Pasteur) | FRANCE |
| University of Adelaide | AUSTRALIA |
| University of Massachusetts Amherst | UNITED STATES |
| University of Massachusetts Medical School | UNITED STATES |
| University of Michigan | UNITED STATES |
| University of Pittsburgh | UNITED STATES |
| University of South Australia | AUSTRALIA |
| Walter and Eliza Hall Institute of Medical Research | AUSTRALIA |
Teaching & student supervision
Supervisions from 2010 shown
| Thesis title | Student status |
|---|---|
| Regulation of autophagy in cell and tissue homeostasis | Current |
| Identifying regulators of autophagy-dependent cell death | Completed |
| Regulation and mechanism of autophagy-dependent developmental cell death in Drosophila melanogaster larval midgut | Completed |
| Regulation of retromer and its role in tauopathies | Completed |
