Having been trained as a Biochemist and establishing a strong desire to work in the area of protein dysfunction and disease pathogenesis I was fortunate to obtain a research position in the Lysosomal Diseases Research Unit at the Women’s in Children’s Hospital. I became involved in research to understand the molecular mechanisms of lysosomal disease pathogenesis and developed diagnostic assays. During this time, I became particularly interested in the neurological dysfunction associated with these diseases, in particular Sanfilippo Syndrome, and commenced a research program looking at the role of altered neurotransmission and disease progression, having been awarded an NHMRC Peter Doherty Early Career Research Fellowship. At... Read more
About me
Having been trained as a Biochemist and establishing a strong desire to work in the area of protein dysfunction and disease pathogenesis I was fortunate to obtain a research position in the Lysosomal Diseases Research Unit at the Women’s in Children’s Hospital. I became involved in research to understand the molecular mechanisms of lysosomal disease pathogenesis and developed diagnostic assays. During this time, I became particularly interested in the neurological dysfunction associated with these diseases, in particular Sanfilippo Syndrome, and commenced a research program looking at the role of altered neurotransmission and disease progression, having been awarded an NHMRC Peter Doherty Early Career Research Fellowship. At the completion of my fellowship I obtained a research-teaching academic position at the University of South Australia.
Serendipity and discussions with Professor Sandra Orgeig have evoked a new research program investigating the molecular mechanisms that may impact respiratory dysfunction in Sanfilippo Syndrome but may also contribute to other lysosomal diseases; underlying molecular mechanisms contributing to both neurological and respiratory dysfunction. This includes a continuing collaboration with Associate Kim Hemsley (Flinders University) and co supervision of PhD students. During my research career thus far, I have had the privilege to attend and present our research findings at several international MPS and related disease conferences and interacted with many amazing patients and their families, clinicians and scientists. This truly reinforces to me why I continue to do what I do.
As a senior scientist in the Mechanisms in Cell Biology and Disease research group I am also been involved in projects focussed on the endosome-lysosome system and cancer pathogenesis.
About me
About me
Doctor of Philosophy The University of Adelaide
Bachelor of Science (Honours) The University of Adelaide
Bachelor of Science The University of Adelaide
Research
Excludes commercial-in-confidence projects.
Quantification of airway disease in MPS II mice via laboratory X-ray velocimetry, The National MPS Society (USA), 01/04/2024 - 31/03/2025
Diagnostic and prognostic biomarker test for prostate cancer, EnVision Sciences Pty Ltd, 01/01/2017 - 30/10/2018
Lung function in a mouse model of a paediatric metabolic mouse, The Australian Lung Foundation, 01/05/2016 - 05/03/2018
Research
Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID, ResearcherID or Scopus
Open access indicates that an output is open access.
Year | Output |
---|---|
2014 |
Open access
18
4
1
|
2012 |
Open access
|
Year | Output |
---|---|
2024 |
Open access
|
2024 |
Open access
|
2024 |
1
|
2023 |
Open access
14
13
84
|
2022 |
13
12
|
2021 |
Open access
14
14
|
2021 |
Open access
12
11
2
|
2021 |
1
1
4
|
2021 |
Open access
7
7
5
|
2020 |
Open access
9
8
1
|
2019 |
Open access
5
5
2
|
2019 |
Open access
6
1
|
2019 |
Open access
36
36
1
|
2019 |
Open access
4
3
68
|
2018 |
Open access
34
5
|
2017 |
32
30
4
|
2015 |
Open access
35
32
11
|
2014 |
19
17
1
|
2014 |
Open access
36
35
11
|
2012 |
16
16
|
2012 |
Open access
20
20
|
2012 |
Open access
|
2010 |
187
174
|
Research
Research
Details | Registry | Status |
---|---|---|
Methods for detecting prostate cancer Brooks, Doug; Parkinson-Lawrence, Emma; Johnson, Ian; Butler, Lisa; Weigert, Roberto |
AU | Filed |
Methods for detecting prostate cancer Brooks, Doug; Parkinson-Lawrence, Emma; Johnson, Ian; Butler, Lisa; Weigert, Roberto |
EP | Filed |
Methods for detecting prostate cancer Brooks, Doug; Parkinson-Lawrence, Emma; Johnson, Ian; Butler, Lisa; Weigert, Roberto |
SG | Filed |
Methods for detecting prostate cancer Brooks, Doug; Parkinson-Lawrence, Emma; Johnson, Ian; Butler, Lisa; Weigert, Roberto |
US | Filed |
Methods for detecting prostate cancer Brooks, Doug; Parkinson-Lawrence, Emma; Johnson, Ian; Butler, Lisa; Weigert, Roberto |
WO | Filed |
External engagement & recognition
Organisation | Country |
---|---|
Australian Society of Medical Research | AUSTRALIA |
Central Queensland University | AUSTRALIA |
Childrens Cancer Institute Australia for Medical Research | AUSTRALIA |
Complutense University of Madrid | SPAIN |
Curtin University | AUSTRALIA |
Flinders University | AUSTRALIA |
Hannover Medical School | GERMANY |
Heart Research Institute | UNITED STATES |
Institute of Medical and Veterinary Science | AUSTRALIA |
Mater Medical Research Institute | AUSTRALIA |
Max Planck Institute for Polymer Research | GERMANY |
Monash University | AUSTRALIA |
Murdoch Childrens Research Institute | AUSTRALIA |
NIDCR | UNITED STATES |
Queensland Institute of Medical Research | AUSTRALIA |
RMIT University | AUSTRALIA |
Royal women's Hospital | AUSTRALIA |
SA Pathology | AUSTRALIA |
South Australian Health and Medical and Research Institute (SAHMRI) | AUSTRALIA |
Technion Israel Institute of Technology | ISRAEL |
Telethon Kids Institute | AUSTRALIA |
The Coombe Hospital | IRELAND |
Trinity College Dublin | IRELAND |
University College Dublin | IRELAND |
University of Adelaide | AUSTRALIA |
University of Bologna | ITALY |
University of Dublin | IRELAND |
University of Melbourne | AUSTRALIA |
University of Pennsylvania | UNITED STATES |
University of South Australia | AUSTRALIA |
University of Southampton | UNITED KINGDOM |
University of Sydney | AUSTRALIA |
University of Technology Sydney | AUSTRALIA |
University of Washington | UNITED STATES |
University of Western Australia | AUSTRALIA |
Women's and Children's Health Network | AUSTRALIA |
Women's and Children's Health Network Incorporated | AUSTRALIA |
Women's and Children's Hospital | AUSTRALIA |
External engagement & recognition
Engagement/recognition | Year |
---|---|
Citations for Outstanding Contributions to Student LearningOffice for Learning and Teaching, Department of Education and Training, Australian Government |
2020 |
PresidentThe Australian Society for Medical Research (ASMR) |
2019 |
MemberAustralian Society for Medical Research (ASMR) |
2018 |
MemberAustralian Society for Biochemistry and Molecular Biology (ASBMB) |
2018 |
Member, Adelaide Protein GroupAustralian Society for Biochemistry and Molecular Biology (ASBMB) |
2018 |
President-elect & sponsorship leadThe Australian Society for Medical Research (ASMR) |
2018 |
Executive Director - sponsorship leadThe Australian Society for Medical Research (ASMR) |
2017 |
MemberAustralian Society for Medical Research (ASMR) |
2017 |
MemberAustralian Society for Biochemistry and Molecular Biology (ASBMB) |
2017 |
Member, Adelaide Protein GroupAustralian Society for Biochemistry and Molecular Biology (ASBMB) |
2017 |
Advisory Board MemberThe Australian Society for Medical Research (ASMR) |
2013 |
Teaching & student supervision
Teaching & student supervision
Supervisions from 2010 shown
Thesis title | Student status |
---|---|
Functional Analysis and Quantification of Biopharmaceuticals in Tissues by Mass Spectrometry Imaging | Current |
Altered lysosomal biogenesis in prostate cancer | Completed |
Altered surfactant and lung function in the Mucopolysaccharidosis IIIA mouse: unravelling the mechanisms of lung disease in Sanfilippo patients | Completed |
Development of targeted luminescent metal complexes for cellular imaging | Completed |
The role of endosomes in innate immunity | Completed |