Dr Genevieve Secker

Research Fellow Centre for Cancer Biology

City West Campus (HB10-25)
tel +61 8 830 27875

email Genevieve.Secker@unisa.edu.au

Research

Research focus

Medical and Health Sciences
Biological Sciences
Clinical Sciences
Multidisciplinary
Ophthalmology

Research

Outputs

Research outputs for the last seven years are shown below. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Chapters

Year	Output
2010	Daniels, J, Secker, GA & Shortt, A 2010, 'Ocular surface restoration', in LA Levin & DM Albert, Ocular Disease: Mechanisms and Management, Elsevier, US, ch.11, pp. 83-90.

Journal Articles

Year	Output
2022	Byrne, AB, Brouillard, P, Sutton, DL, Kazenwadel, J, Montazaribarforoush, S, Secker, GA, Oszmiana, A, Babic, M, Betterman, KL, Brautigan, PJ, Hahn, CN, Arts, P, Scott, HS & Harvey, NL and 18 other authors 2022, 'Pathogenic variants in MDFIC cause recessive central conducting lymphatic anomaly with lymphedema', Science Translational Medicine, vol. 14, no. 634, article no. eabm4869, pp. 1-14. 4 4 194
2022	Lohraseb, I, McCarthy, P, Secker, G, Marchant, C, Wu, J, Ali, N, Kumar, S, Daly, RJ, Harvey, NL, Kawabe, H, Kleifeld, O, Wiszniak, S & Schwarz, Q 2022, 'Global ubiquitinome profiling identifies NEDD4 as a regulator of Profilin 1 and actin remodelling in neural crest cells', Nature Communications, vol. 13, no. 1, pp. 1-18. Open access 2 2 7
2021	Secker, GA & Harvey, NL 2021, 'Regulation of vegfr signalling in lymphatic vascular development and disease: an update', International Journal of Molecular Sciences, vol. 22, no. 14, article no. 7760, pp. 1-16. Open access 17 17 1
2020	Betterman, KL, Sutton, DL, Secker, GA, Kazenwadel, J, Oszmiana, A, Lim, L, Miura, N, Sorokin, L, Hogan, BM, Kahn, ML, McNeill, H & Harvey, NL 2020, 'Atypical cadherin Fat4 orchestrates lymphatic endothelial cell polarity in response to flow', Journal of Clinical Investigation, online, pp. 1-15. Open access 32 30 23
2019	Baek, S, Oh, TG, Secker, G, Sutton, DL, Okuda, KS, Paterson, S, Bower, N I, Toubia, J, Koltowska, K, Capon, SJ, Baillie, GJ, Simons, C, Muscat, GE, Lagendijk, AK, Smith, KA, Harvey, NL & Hogan, BM 2019, 'The alternative splicing regulator nova2 constrains vascular erk signaling to limit specification of the lymphatic lineage', Developmental Cell, vol. 49, no. 2, pp. 279-292.e5. Open access 19 19 12
2017	Lumb, R, Buckberry, S, Secker, G, Lawrence, DM & Schwarz, Q 2017, 'Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels', BMC Developmental Biology, vol. 17, article no. 5, pp. 1-12. Open access 18 18 2
2015	Kazenwadel, J, Betterman, KL, Chong, C-E, Stokes, PH, Lee, YK, Secker, GA, Agalarov, Y, Demir, CS, Lawrence, DM, Sutton, DL, Tabruyn, SP, Miura, N, Salminen, M, Petrova, T, Matthew, JM, Hahn, CN, Scott, HS & Harvey, NL 2015, 'GATA2 is required for lymphatic vessel valve development and maintenance', Journal of Clinical Investigation, vol. 125, no. 8, pp. 2979-2994. Open access 143 132 6
2015	Secker, G & Harvey, N 2015, 'VEGFR signaling during lymphatic vascular development: From progenitor cells to functional vessels', Developmental Dynamics, vol. 244, no. 3, pp. 323-331. Open access 67 64
2014	Bowles, J, Secker, GA, Nguyen, C, Kazenwadel, JS, Truong, V, Frampton, E, Curtis, C, Skoczylas, R, Davidson, T-L, Miura, N, Hong, Y-k, Koopman, P, Harvey, NL & Francois, M 2014, 'Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo', Developmental Biology, vol. 386, no. 1, pp. 25-33. Open access 34 31
2013	Wiszniak, S, Kabbara, E, Lumb, R, Scherer, M, Secker, G, Harvey, N, Kumar, S & Schwarz, Q 2013, 'The ubiquitin ligase Nedd4 regulates craniofacial development by promoting cranial neural crest cell survival and stem-cell like properties', Developmental Biology, vol. 383, no. 2, pp. 186-200. Open access 21 25 4
2012	François, M, Short, K, Secker, GA, Combes, A, Schwarz, QP, Davidson, T-L, Smyth, I, Hong, Y-K, Harvey, NL & Koopman, P 2012, 'Segmental territories along the cardinal veins generate lymph sacs via a ballooning mechanism during embryonic lymphangiogenesis in mice', Developmental Biology, vol. 364, no. 2, pp. 89-98. Open access 70 69 3
2012	Kazenwadel, J, Secker, GA, Betterman, KL & Harvey, NL 2012, 'In vitro assays using primary embryonic mouse lymphatic endothelial cells uncover key roles for FGRF1 signalling in lymphangiogenesis', PLoS One, vol. 7, no. 7, article no. 0040497, pp. 1-12. Open access 34 33 1
2012	Kazenwadel, J, Secker, GA, Liu, YJ, Rosenfeld, JA, Chong, C-E, Scott, HS & Harvey, NL and 14 other authors 2012, 'Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature', Blood, vol. 119, no. 5, pp. 1283-1291. Open access 209 191
2012	Radhakrishnan, SS, Blalock, TD, Robinson, PM, Secker, G, Daniels, J, Grotendorst, GR & Schultz, GS 2012, 'Effect of connective tissue growth factor on protein kinase expression and activity in human corneal fibroblasts', Investigative Ophthalmology and Visual Science, vol. 53, no. 13, pp. 8076-8085. Open access 15 13
2009	Shortt, AJ, Secker, GA, Lomas, RJ, Wilshaw, SP, Kearney, JN, Tuft, SJ & Daniels, JT 2009, 'The effect of amniotic membrane preparation method on its ability to serve as a substrate for the ex-vivo expansion of limbal epithelial cells', Biomaterials, vol. 30, no. 6, pp. 1056-1065. 102 92
2008	Secker, GA & Daniels, J 2008, 'Corneal epithelial stem cells: Deficiency and regulation', Stem Cell Reviews, vol. 4, no. 3, pp. 159-168. 51 43
2008	Secker, GA, Shortt, A, Sampson, E, Schwarz, QP & Daniels, J 2008, 'TGFBeta stimulated re-epithelialisation is regulated by CTGF and Ras/MEK/ERK signalling', Experimental Cell Research, vol. 314, no. 1, pp. 131-142. 77 69
2008	Shortt, A, Secker, GA, Rajan, M, Meligonis, G, Dart, J, Tuft, S & Daniels, J 2008, 'Ex Vivo Expansion and Transplantation of Limbal Epithelial Stem Cells', Ophthalmology, vol. 115, no. 11, pp. 1989-1997. 147 135
2008	Watson, S, Secker, GA & Daniels, J 2008, 'The effect of therapeutic human serum drops on corneal stromal wound-healing activity', Current Eye Research, vol. 33, no. 8, pp. 641-652. 15 12

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Centre Hospitalier Universitaire Vaudois	SWITZERLAND
de Duve Institute	BELGIUM
Ecole Polytechnique	FRANCE
Garvan Institute of Medical Research	AUSTRALIA
Hamamatsu University	JAPAN
Hamamatsu University School of Medicine	JAPAN
Hanson Centre for Cancer Research	AUSTRALIA
Harry Perkins Institute of Medical Research	AUSTRALIA
Lovelace Respiratory Research Institute	UNITED STATES
Max Planck Institute of Experimental Medicine	GERMANY
Monash University	AUSTRALIA
Moorfields Eye Hospital	UNITED KINGDOM
NHS Blood and Transplant Tissue Services	UNITED KINGDOM
Perkin Elmer Pty Ltd	UNITED STATES
SA Pathology	AUSTRALIA
Technion Israel Institute of Technology	ISRAEL
UCL Institute of Ophthalmology	UNITED KINGDOM
University of Adelaide	AUSTRALIA
University of Florida	UNITED STATES
University of Helsinki	FINLAND
University of Leeds	UNITED KINGDOM
University of London	UNITED KINGDOM
University of Muenster	GERMANY
University of Pennsylvania	UNITED STATES
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Southern California	UNITED STATES
University of Sydney	AUSTRALIA
University of Toronto	CANADA
University of Washington	UNITED STATES

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Dr Genevieve Secker

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Chapters

Journal Articles

External engagement & recognition

Collaborations

Collaborations

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