Dr Gokhan Cildir

Senior Research Fellow Centre for Cancer Biology

City West Campus (HB11-25)
tel +61 8 830 27922

email Gokhan.Cildir@unisa.edu.au

Research Degree Supervisor

Research

Research focus

Immunology
Biochemistry and Cell Biology
Medical and Health Sciences
Oncology and Carcinogenesis
Biological Sciences

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Journal Articles

Year	Output
2024	Aba, Ü, Maslak, İC, İpşir, C, Pehlivan, D, Warnock, N I, Tumes, DJ, Cildir, G & Erman, B 2024, 'A novel homozygous germline mutation in transferrin receptor 1 (TfR1) leads to combined immunodeficiency and provides new insights into iron-immunity axis', Journal of Clinical Immunology, vol. 44, no. 2, article no. 55, pp. 1-14. Open access 3 2 7
2024	Bayram Catak, F, Catak, MC, Babayeva, R, Toubia, J, Warnock, N I, Kok, CH, Cildir, G & Baris, S and 16 other authors 2024, 'Ruxolitinib treatment ameliorates clinical, immunologic, and transcriptomic aberrations in patients with STAT3 gain-of-function disease', Journal of Allergy and Clinical Immunology, online.
2024	Cildir, G, Aba, U, Pehlivan, D, Tvorogov, D, Warnock, N I, Kok, CH, Tumes, DJ & Erman, B and 17 other authors 2024, 'Defective kinase activity of IKKα leads to combined immunodeficiency and disruption of immune tolerance in humans', Nature Communications, vol. 15, no. 1, pp. 1-18. Open access
2024	Erman, B, Aba, U, Ipsir, C, Pehlivan, D, Cildir, G & Tezcan, I and 40 other authors 2024, 'Genetic evaluation of the patients with clinically diagnosed inborn errors of immunity by whole exome sequencing: results from a specialized research center for immunodeficiency in Türkiye', Journal of Clinical Immunology, vol. 44, no. 7, article no 157, pp. 1-19. Open access 1
2024	Wallach, I, Bernard, D, Nguyen, K, Ho, G, Tumes, D, Cildir, G & Heifets, A and 680 other authors, all authors are part of the The Atomwise AIMS Program 2024, 'AI is a viable alternative to high throughput screening: a 318-target study', Scientific Reports, vol. 14, no. 1, pp. 1-16. Open access 25 81
2024	Wang, H, Yip, KH, Keam, SP, Vlahos, R, Nichol, K, Wark, P, Toubia, J, Kral, AC, Cildir, G, Pant, H, Hercus, TR, Wilson, N, Owczarek, C, Lopez, AF, Bozinovski, S & Tumes, DJ 2024, 'Dual inhibition of airway inflammation and fibrosis by common β cytokine receptor blockade', Journal of Allergy and Clinical Immunology, vol. 153, no. 3, pp. 672-683.e6. Open access 2 67
2023	Conn, VM, Gabryelska, M, Toubia, J, Kirk, K, Powell, JA, Cildir, G, Samaraweera, SE, Bailey, S, Liu, D, Wallington-Gates, CT, D'Andrea, RJ, Pitson, SM, Goodall, GJ & Conn, SJ and 15 other authors 2023, 'Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia', Cancer Cell, vol. 41, no. 7, pp. 1309-1326. 33 31 268
2021	Cildir, G & Tumes, DJ 2021, 'DOT1L leaves its mark on adaptive immunity', Immunology and Cell Biology, vol. 99, no. 4, pp. 348-350. Open access 7
2021	Cildir, G, Yip, KH, Pant, H, Tergaonkar, V, Lopez, AF & Tumes, DJ 2021, 'Understanding mast cell heterogeneity at single cell resolution', Trends in Immunology, vol. 42, no. 6, pp. 523-535. Open access 25 23 5
2021	De Silva, AP, Schembri, MA, Sarah, AH, Chao, J, Yip, KH, Cildir, G, Lopez, A, Tumes, DJ & Pant, H 2021, 'Short-term oral steroids significantly improves chronic rhinosinusitis without nasal polyps', The Laryngoscope, vol. 131, no. 10, pp. E2618-E2626. 5 5 3
2021	Gutiérrez, S, Fischer, J, Ganesan, R, Judith, NH, Cildir, G, Wolke, M, Pessia, A, Frommolt, P, Desiderio, V, Velagapudi, V & Robinson, N 2021, 'Salmonella Typhimurium impairs glycolysis-mediated acidification of phagosomes to evade macrophage defense', PLoS Pathogens, vol. 17, no. 9, article no. e1009943. Open access 18 16 7
2021	Mansilla, MO, Salazar-Hernandez, C, Perrin, SL, Scheer, KG, Cildir, G, Toubia, J, Sedivakova, K, Tea, MN, Lenin, S, Ponthier, E, Yeo, EC, Tergaonkar, V, Poonnoose, S, Ormsby, RJ, Pitson, SM, Brown, MP, Ebert, LM & Gomez, GA 2021, '3D-printed microplate inserts for long term high-resolution imaging of live brain organoids', BMC Biomedical Engineering, vol. 3, article no. 6, pp. 1-13. Open access 14
2019	Cildir, G, Toubia, J, Yip, KH, Zhou, M, Pant, H, Hissaria, P, Zhang, J, Hong, W, Robinson, N, Grimbaldeston, MA, Lopez, AF & Tergaonkar, V 2019, 'Genome-wide analyses of chromatin state in human mast cells reveal molecular drivers and mediators of allergic and inflammatory diseases', Immunity, vol. 51, no. 5, pp. 949-965.e6. Open access 41 42 12
2019	Fischer, J, Gutièrrez, S, Ganesan, R, Calabrese, C, Ranjan, R, Cildir, G, Hos, NJ, Rybniker, J, Wolke, M, Fries, JW, Tergaonkar, V, Plum, G, Antebi, A & Robinson, N 2019, 'Leptin signaling impairs macrophage defenses against Salmonella Typhimurium', Proceedings of the National Academy of Sciences of USA, vol. 116, no. 33, pp. 16551-16560. Open access 18 17 8
2019	Khattar, E, Maung, KZY, Chew, CL, Ghosh, A, Cildir, G & Tergaonkar, V 2019, 'Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy', Nature Communications, vol, 10, no. 1, article no. 5349, pp. 1-14. Open access 46 44 12
2018	Maung, KZY, Leo, PJ, Bassal, M, Casolari, DA, Bray, SC, Singhal, D, Samaraweera, SE, Nguyen, T, Cildir, G, Tergaonkar, V, Lewis, I, Brown, AL, D'Andrea, RJ & Gonda, TJ and 11 other authors 2018, 'Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia', Blood Cancer Journal, vol. 8, no. 6, article no. 50, pp. 1-5. Open access 15 15 3
2017	Cildir, G, Pant, H, Lopez, AF & Tergaonkar, V 2017, 'The transcriptional program, functional heterogeneity, and clinical targeting of mast cells', Journal of Experimental Medicine, vol. 214, no. 9, pp. 2491-2506. Open access 77 73 11
2017	Conn, VM, Hugouvieux, V, Nayak, A, Conos, SA, Capovilla, G, Cildir, G, Jourdain, A, Tergaonkar, V, Schmid, M, Zubieta, C & Conn, SJ 2017, 'A circRNA from SEPALLATA3 regulates splicing of its cognate mRNA through R-loop formation', Nature Plants, vol. 3, article no. 17053, pp. 1-5. 458 429 23
2016	Cildir, G, Low, KC & Tergaonkar, V 2016, 'Noncanonical NF-κB signaling in health and disease', Trends in Molecular Medicine, vol. 22, no. 5, pp. 414-429. 241 232 10
2013	Cildir, G, Akincilar, SC & Tergaonkar, V 2013, 'Chronic adipose tissue inflammation: all immune cells on the stage', Trends in Molecular Medicine, vol. 19, no. 8, pp. 487-500. 247 235

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Agency for Science Technology & Research (ASTAR)	UNITED STATES
A-Star, Institute of Molecular and Cell Biology	SINGAPORE
Atomwise Inc.	UNITED STATES
CSL Limited	AUSTRALIA
Flinders Medical Centre	AUSTRALIA
Flinders University	AUSTRALIA
Genentech, Inc.	UNITED STATES
Hacettepe University	TURKEY
Institute for Molecular Medicine Finland	FINLAND
Institute of Molecular and Cell Biology, Singapore	SINGAPORE
Marmara University	TURKEY
Max Planck Institute of Evolutionary Biology	GERMANY
National University of Singapore	SINGAPORE
Queensland University of Technology	AUSTRALIA
RMIT University	AUSTRALIA
Royal Adelaide Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
Süleyman Demirel University	TURKEY
Umea University	SWEDEN
University of Adelaide	AUSTRALIA
University of Campania Luigi Vanvitell	ITALY
University of Cologne	GERMANY
University of Grenoble	FRANCE
University of Newcastle	AUSTRALIA
University of South Australia	AUSTRALIA

External engagement & recognition

Engagement/recognition	Year
CUT&RUN Award Integrated Sciences, Australia	2021
Artificial Intelligence Molecular Screen (AIMS) Award Atomwise, San Francisco, USA	2020
Artificial Intelligence Molecular Screen (AIMS) Award Atomwise, San Francisco, USA	2019
Early Career Fellowship The Hospital Research Foundation (THRF)	2019
Travel Award 9th European Mast Cell and Basophil Research Network (EMBRN) International Mast Cell and Basophil Meeting, Uppsala, Sweden	2019
Young Investigator Award International Association of Inflammation Societies (IAIS) 14th World Congress on Inflammation 2019, Sydney, Australia	2019
Award Singapore International Graduate Award	2015
PhD Scholarship Singapore International Graduate Award (SINGA)	2015
Award Singapore International Graduate Award	2014
PhD Scholarship Singapore International Graduate Award (SINGA)	2014
Award Singapore International Graduate Award	2013
PhD Scholarship Singapore International Graduate Award (SINGA)	2013
Award Singapore International Graduate Award	2012
PhD Scholarship Singapore International Graduate Award (SINGA)	2012
Award Singapore International Graduate Award	2011
PhD Scholarship Singapore International Graduate Award (SINGA)	2011
President of AEGEEÂ¿Urla (European Students Forum) AEGEEÂ¿Urla	2011
RectorÂ¿s List of Outstanding Students Izmir Institute of Technology, Izmir, Turkey	2011
ERASMUS Intern Scholarship The Robert Koch Institute (RKI), Berlin, Germany	2010
President of AEGEEÂ¿Urla (European Students Forum) AEGEEÂ¿Urla	2010
President of AEGEEÂ¿Urla (European Students Forum) AEGEEÂ¿Urla	2009
President of AEGEEÂ¿Urla (European Students Forum) AEGEEÂ¿Urla	2008

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
Deciphering how airway epithelial programming and inflammation cause chronic allergic airways disease	Current
Elucidating the functions of novel genetic drivers of common inflammatory diseases	Current

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Dr Gokhan Cildir

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Journal Articles

External engagement & recognition

Collaborations

Collaborations

External engagement & recognition

CUT&RUN Award

Artificial Intelligence Molecular Screen (AIMS) Award

Artificial Intelligence Molecular Screen (AIMS) Award

Early Career Fellowship

Travel Award

Young Investigator Award

Award

PhD Scholarship

Award

PhD Scholarship

Award

PhD Scholarship

Award

PhD Scholarship

Award

PhD Scholarship

President of AEGEEÂ¿Urla (European Students Forum)

RectorÂ¿s List of Outstanding Students

ERASMUS Intern Scholarship

President of AEGEEÂ¿Urla (European Students Forum)

President of AEGEEÂ¿Urla (European Students Forum)

President of AEGEEÂ¿Urla (European Students Forum)

Teaching & student supervision

Courses and programs

Research degree supervision

Gallery