Professor Greg Goodall

Adjunct Professor Centre for Cancer Biology

City West Campus (HB9-15)
tel +61 8 830 27751

email Greg.Goodall@unisa.edu.au

Research Degree Supervisor

Research

Research focus

Biological Sciences
Medical and Health Sciences
Biochemistry and Cell Biology
Clinical Sciences
Information and Computing Sciences

Research

Projects

Excludes commercial-in-confidence projects.

Characterising an RNA splicing pathway driving prostate cancer metastasis and therapy resistance, NHMRC - Project Grant, 01/01/2019 - 31/12/2022
Discovering how microRNAs and circRNAs control cancer metastasis, NHMRC - Research Fellowship, 01/01/2017 - 31/12/2021
Use of a new molecule (miR-342) to discover important pathways to treat advanced breast cancer, NBCF - Investigator Initiated Research Scheme, 01/01/2018 - 01/07/2021
Develop efficient data mining methods for evidence based decision making, ARC - Discovery Projects, 29/06/2017 - 28/06/2021
Functions of circular RNAs, NHMRC - Project Grant, 01/01/2017 - 31/12/2019
Using miR-200 to find new therapeutic targets for neuroblastoma, NHMRC - Project Grant, 01/01/2017 - 31/12/2019
Characterising novel alternative splicing networks that promote tumour cell plasticity, NHMRC - Project Grant, 01/01/2017 - 31/12/2019
Cancer Discovery Accelerator, Australian Cancer Research Foundation, 01/06/2016 - 31/07/2018
Targeting microRNA-driven mesenchymal to epithelial transition to suppress prostate cancer metastasis, NHMRC - Project Grant, 01/01/2015 - 31/12/2017
Do circular RNAs affect breast cancer progression?, National Breast Cancer Foundation - Innovator Grant, 01/01/2016 - 31/12/2017
Formation and function of circular RNAs in human cells, NHMRC - Project Grant, 01/01/2015 - 31/12/2017
Role of the microRNA target Quaking in alternative splicing during EMT and cancer progression, NHMRC - Project Grant, 01/01/2014 - 31/12/2017
Cancer Discovery Accelerator, Cancer Council SA - Beat Cancer, 08/06/2016 - 08/06/2017
miR-200 and its targets as inhibitors of neuroblastoma growth and metastasis, Channel 7 Children's Research Foundation of SA, 01/01/2015 - 31/12/2016
MicroRNAs and cancer metastasis, NHMRC - Research Fellowship, 01/01/2014 - 31/12/2016
How isomiRs expand the microRNA functional repertoire in affecting gene expression, NHMRC - Project Grant, 01/01/2014 - 31/12/2016

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID

Open access indicates that an output is open access.

Chapters

Year	Output
2018	Liu, D, Conn, V, Goodall, GJ & Conn, SJ 2018, 'A highly efficient strategy for overexpressing circRNAs', in C Dieterich & A Papantonis (eds), Circular RNAs, Humana Press, US, ch. 8, pp. 97-105. 16

Journal Articles

Year	Output
2024	Bracken, CP, Goodall, GJ & Gregory, PA 2024, 'RNA regulatory mechanisms controlling TGF-β signaling and EMT in cancer', Seminars in Cancer Biology, vol. 102-103, pp. 4-16. Open access 2
2024	Liu, D, Dredge, BK, Bert, AG, Pillman, KA, Toubia, J, Guo, W, Dyakov, BJ, Migault, MM, Conn, VM, Conn, SJ, Gregory, PA, Gingras, A-C, Patel, D, Wu, B & Goodall, GJ 2024, 'ESRP1 controls biogenesis and function of a large abundant multiexon circRNA', Nucleic Acids Research, vol. 52, no. 3, pp. 1387-1403. Open access 2
2024	Liu, L, Neve, M, Perlaza-Jimenez, L, Xi, X, Purcell, J, Hawdon, A, Conn, SJ, Zenker, J, Tamayo, P, Goodall, GJ & Rosenbluh, J 2024, 'Systematic loss-of-function screens identify pathway-specific functional circular RNAs', Nature Cell Biology, vol. 26, pp. 1359-1372.
2024	Neumann, DP, Phillips, CA, Lumb, R, Palethorpe, HM, Ramani, Y, Hollier, BG, Selth, LA, Bracken, CP, Goodall, GJ & Gregory, PA 2024, 'Quaking isoforms cooperate to promote the mesenchymal phenotype', Molecular Biology of the Cell, vol. 35, no. 2, pp. 1-17. Open access 1
2024	Neumann, DP, Pillman, KA, Dredge, BK, Bert, AG, Phillips, CA, Lumb, R, Ramani, Y, Bracken, CP, Hollier, BG, Selth, LA, Beilharz, TH, Goodall, GJ & Gregory, PA 2024, 'The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking', RNA Biology, vol. 21, no. 1, article no. 100928, pp. 1-11. Open access 2 1
2024	Ngo, LH, Bert, AG, Dredge, BK, Williams, T, Murphy, V, Li, W, Hamilton, WB, Carey, KT, Toubia, J, Pillman, KA, Liu, D, Desogus, J, Chao, JA, Deans, AJ, Goodall, GJ & Wickramasinghe, VO 2024, 'Nuclear export of circular RNA', Nature, vol. 627, no 8002, pp. 212-220. 11
2023	Conn, VM, Gabryelska, M, Toubia, J, Kirk, K, Powell, JA, Cildir, G, Samaraweera, SE, Bailey, S, Liu, D, Wallington-Gates, CT, D'Andrea, RJ, Pitson, SM, Goodall, GJ & Conn, SJ and 15 other authors 2023, 'Circular RNAs drive oncogenic chromosomal translocations within the MLL recombinome in leukemia', Cancer Cell, vol. 41, no. 7, pp. 1309-1326. 27 225
2023	Kan, WL, Dhagat, U, Kaufmann, KB, Hercus, TR, Toubia, J, Barry, EF, Gomez, GA, Dottore, M, Samaraweera, SE, Goodall, GJ, Thomas, D, Tvorogov, D, D'Andrea, RJ & Lopez, AF and 12 other authors 2023, 'Distinct assemblies of heterodimeric cytokine receptors govern stemness programs in leukemia', Cancer Discovery, vol. 13, no. 8, pp. 1922-1947. Open access 4 20
2023	Orang, A, Dredge, BK, Liu, CY, Bracken, JM, Chen, CH, Sourdin, L, Whitfield, HJ, Lumb, R, Boyle, ST, Davis, MJ, Samuel, MS, Gregory, PA, Khew-Goodall, Y, Goodall, GJ, Pillman, KA & Bracken, CP 2023, 'Basonuclin-2 regulates extracellular matrix production and degradation', Life Science Alliance, vol. 6, no. 10, article no. e202301984. Open access 2
2023	Sapkota, S, Pillman, KA, Dredge, BK, Liu, D, Bracken, JM, Kachooei, SA, Chereda, B, Gregory, PA, Bracken, CP & Goodall, GJ 2023, 'On the rules of engagement for microRNAs targeting protein coding regions', Nucleic Acids Research, vol. 51, no. 18, pp. 9938-9951. Open access 3 4
2022	Bracken, CP & Goodall, GJ 2022, 'The many regulators of epithelial−mesenchymal transition', Nature Reviews Molecular Cell Biology, vol. 23 no. 2, pp. 89-90. 39 38 3
2022	Lewis, AC, Pope, VS, Tea, MN, Li, M, Nwosu, GO, Nguyen, TM, Wallington-Beddoe, CT, Moretti, PA, Costabile, M, Ali, SR, Dredge, BK, Bert, AG, Goodall, GJ, Brown, AL, D'Andrea, R, Robinson, N, Pitman, MR, Ross, DM, Gliddon, BL, Powell, JA & Pitson, SM and 5 other authors 2022, 'Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia', Blood, vol. 139, no. 26, pp. 3737-3751. Open access 23 21 72
2022	Neumann, DP, Goodall, GJ & Gregory, PA 2022, 'The Quaking RNA-binding proteins as regulators of cell differentiation', Wiley interdisciplinary reviews. RNA, vol. 13, no. 6, article no. e1724, pp. 1-19. Open access 19 19 1
2021	Fernandes, RC, Toubia, J, Townley, S, Hanson, AR, Dredge, BK, Pillman, KA, Bert, AG, Gregory, PA, Goodall, GJ & Selth, LA and 12 other authors 2021, 'Post-transcriptional gene regulation by microRNA-194 promotes neuroendocrine transdifferentiation in prostate cancer', Cell Reports, vol. 34, no. 1, article no. 108585, pp. 1-24. Open access 30 31 120
2021	Goodall, GJ & Wickramasinghe, VO 2021, 'RNA in cancer', Nature Reviews Cancer, vol. 21, pp. 22-36. Open access 708 697
2021	Jensen, KB, Dredge, BK, Toubia, J, Jin, X, Iadevaia, V, Goodall, GJ & Proud, CG 2021, 'capCLIP: a new tool to probe translational control in human cells through capture and identification of the eIF4E-mRNA interactome', Nucleic Acids Research, vol. 49, no. 18, pp. e105 -1-e105-15. Open access 14 13
2021	Kurosaki, M, Terao, M, Liu, D, Zanetti, A, Guarrera, L, Bolis, M, Gianni', M, Paroni, G, Goodall, GJ & Garattini, E 2021, 'A dock1 gene-derived circular rna is highly expressed in luminal mammary tumours and is involved in the epithelial differentiation, growth, and motility of breast cancer cells', Cancers, vol. 13, no. 21, article no.5325, pp. 1-19. Open access 8 6
2021	Lonic, A, Gehling, F, Belle, L, Li, X, Schieber, NL, Nguyen, E V, Goodall, GJ, Parton, RG, Daly, RJ & Khew-Goodall, Y 2021, 'Phosphorylation of PKCδ by FER tips the balance from EGFR degradation to recycling', The Journal of Cell Biology, vol. 220, no. 1, pp. 1-27. Open access 18 17 8
2021	Pham, VV, Liu, L, Bracken, CP, Nguyen, T, Goodall, GJ, Li, J & Le, TD 2021, 'pDriver: a novel method for unravelling personalized coding and miRNA cancer drivers', Bioinformatics, vol. 37, no. 9, pp. 3285-3292. Open access 11 11 2
2020	Pham, VV, Liu, L, Bracken, CP, Goodall, GJ, Li, J & Le, TD 2020, 'DriverGroup: a novel method for identifying driver gene groups', Bioinformatics, vol. 36, no. S2, pp. i583-i591. Open access 6 7 1
2020	Po'uha, ST, Le Grand, M, Brandl, MB, Gifford, AJ, Goodall, GJ, Khew-Goodall, Y & Kavallaris, M 2020, 'Stathmin levels alter PTPN14 expression and impact neuroblastoma cell migration', British Journal of Cancer, vol. 122, pp. 434-444. Open access 9 9
2020	Saunders, K, Bert, AG, Dredge, BK, Toubia, J, Gregory, PA, Pillman, KA, Goodall, GJ & Bracken, CP 2020, 'Insufficiently complex unique-molecular identifiers (UMIs) distort small RNA sequencing', Scientific Reports, vol. 10, no. 1, pp. 1-9. Open access 9 8 9
2020	Yang, J, Antin, P, Berx, G, Blanpain, C, Goodall, GJ, Khew-Goodall, Y & Sheng, G and 40 other authors and 1 consortia 2020, 'Guidelines and definitions for research on epithelial-mesenchymal transition', Nature Reviews Molecular Cell Biology, vol. 21, no. 6, pp. 341-352. Open access 1191 1085
2019	Pham, VV, Liu, L, Bracken, CP, Goodall, GJ, Long, Q, Li, J & Le, TD 2019, 'CBNA: A control theory based method for identifying coding and non-coding cancer drivers', PLoS Computational Biology, vol. 15, no. 12, article no. e1007538, pp. 1-12. Open access 22 21 5
2019	Pillman, KA, Goodall, GJ, Bracken, CP & Gantier, MP 2019, 'miRNA length variation during macrophage stimulation confounds the interpretation of results: implications for miRNA quantification by RT-qPCR', Rna-A Publication of the Rna Society, vol. 25, no. 2, pp. 232-238. Open access 14 14 1
2019	Pillman, KA, Scheer, KG, Hackett-Jones, E, Saunders, K, Bert, AG, Toubia, J, Whitfield, HJ, Sapkota, S, Sourdin, L, Pham, H, Le, TD, Cursons, J, Davis, MJ, Gregory, PA, Goodall, GJ & Bracken, CP 2019, 'Extensive transcriptional responses are co-ordinated by microRNAs as revealed by Exon-Intron Split Analysis (EISA)', Nucleic Acids Research, vol. 47, no. 16, pp. 8606-8619. Open access 6 5 5
2019	Pinweha, P, Phillips, CA, Gregory, PA, Li, X, Chuayboonya, P, Mongkolsiri, P, Goodall, GJ & Jitrapakdee, S 2019, 'MicroRNA-143-3p targets pyruvate carboxylase expression and controls proliferation and migration of MDA-MB-231 cells', Archives of Biochemistry and Biophysics, vol. 677, article no. 108169, pp. 1-10. 14 16 1
2019	Ragan, C, Goodall, GJ, Shirokikh, NE & Preiss, T 2019, 'Insights into the biogenesis and potential functions of exonic circular RNA', Scientific Reports, vol. 9, no. 1, pp. 1-18. Open access 104 96
2018	Boulding, T, McCuaig, R, Tan, A, Hardy, K, Wu, F, Dunn, J, Kalimutho, M, Sutton, C, Forwood, J, Bert, A, Goodall, G, Malik, L, Yip, D, Dahlstrom, J, Zafar, A, Khanna, K & Rao, S 2018, 'LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer', Scientific Reports, vol. 8, no. 1, article no. 73, pp. 1-18. Open access 112 110
2018	Brown, CY, Dayan, S, Wong, SW, Kaczmarek, A, Hope, CM, Pederson, SM, Arnet, V, Goodall, GJ, Russell, D, Sadlon, TJ & Barry, SC 2018, 'FOXP3 and miR-155 cooperate to control the invasive potential of human breast cancer cells by down regulating ZEB2 independently of ZEB1', Oncotarget, vol. 9, no. 45, pp. 27708-27727. Open access 19
2018	Cursons, J, Pillman, KA, Scheer, KG, Gregory, PA, Foroutan, M, Hediyeh-Zadeh, S, Toubia, J, Crampin, EJ, Goodall, GJ, Bracken, CP & Davis, MJ 2018, 'Combinatorial targeting by microRNAs co-ordinates post-transcriptional control of EMT', Cell Systems, vol. 7, no. 1, pp. 77-91. Open access 72 67 28
2018	Nejad, C, Pillman, KA, Siddle, KJ, Pépin, G, Anko, ML, McCoy, CE, Beilharz, TH, Quintana-Murci, L, Goodall, GJ, Bracken, CP & Gantier, MP 2018, 'miR-222 isoforms are differentially regulated by type-I interferon', Rna-A Publication of the Rna Society, vol. 24, no. 3, pp. 332-341. Open access 28 26 2
2018	Neumann, DP, Goodall, GJ & Gregory, PA 2018, 'Regulation of splicing and circularisation of RNA in epithelial mesenchymal plasticity', Seminars in Cell and Developmental Biology, vol. 75, pp. 50-60. Open access 20 18 1
2018	Pillman, KA, Phillips, CA, Roslan, S, Toubia, J, Dredge, BK, Bert, AG, Lumb, R, Neumann, DP, Li, X, Conn, SJ, Liu, D, Bracken, CP, Lawrence, DM, Schreiber, AW, Khew-Goodall, Y, Goodall, GJ & Gregory, PA and 4 other authors 2018, 'miR‐200/375 control epithelial plasticity‐associated alternative splicing by repressing the RNA‐binding protein Quaking', The EMBO Journal, vol. 37, no. 13, article no. e99016, pp. 1-20. Open access 78 78 15
2018	Yu, L, Di, W, Gao, H, Balic, JJ, Tsykin, A, Han, T-S, Liu, YD, Kennedy, CL, Li, JK, Mao, JQ, Tan, P, Oshima, M, Goodall, GJ & Jenkins, BJ 2018, 'Clinical utility of a STAT3-regulated miRNA-200 family signature with prognostic potential in early gastric cancer', Clinical Cancer Research, vol. 24, no. 6, pp. 1459-1472. Open access 40 36
2017	Das, R, Gregory, PA, Fernandes, RC, Denis, I, Lokman, NA, Ramshaw, HS, Goodall, GJ & Selth, LA 2017, 'MicroRNA-194 promotes prostate cancer metastasis by inhibiting SOCS2', Cancer Research, vol. 77, no. 4, pp. 1021-1034. Open access 97 98 61
2017	Narayan, N, Morenos, L, Phipson, B, Willis, S, Brumatti, G, Eggers, S, Lalaoui, N, Brown, L, Kosasih, H, Bartolo, R, Zhou, L, Catchpoole, D, Saffery, R, Oshlack, A, Goodall, G & Ekert, P 2017, 'Functionally distinct roles for different miR-155 expression levels through contrasting effects on gene expression, in acute myeloid leukaemia', Leukemia, vol. 31, no. 4, pp. 808-820. 43 42
2017	Selth, L, Das, R, Townley, S, Coutinho, I, Hanson, A, Centenera, M, Stylianou, N, Sweeney, K, Soekmadji, C, Jovanovic, L, Nelson, C, Zoubeidi, A, Butler, L, Goodall, G, Hollier, B, Gregory, P & Tilley, W 2017, 'A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer', Oncogene, vol. 36, pp. 24-34. Open access 90 88 11
2017	Yu, F, Pillman, KA, Neilsen, CT, Toubia, J, Lawrence, DM, Tsykin, A, Gantier, MP, Callen, DF, Goodall, GJ & Bracken, CP 2017, 'Naturally existing isoforms of miR-222 have distinct functions', Nucleic Acids Research, vol. 45, no. 19, pp. 1137-11385. Open access 58 55 6
2016	Bracken, CP, Scott, HS & Goodall, GJ 2016, 'A network-biology perspective of microRNA function and dysfunction in cancer', Nature Reviews Genetics, vol. 17, pp. 719-732. Open access 567 542 33
2015	Belle, L, Ali, N, Lonic, A, Li, X, Paltridge, JL, Roslan, S, Herrmann, D, Gehling, FK, Bert, AG, Crocker, L, Tsykin, A, Farshid, G, Goodall, GJ, Timpson, P, Daly, R & Khew-Goodall, Y 2015, 'The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking', Science Signaling, vol. 8, no. 364, article no. ra18, pp. 1-12. 53 52 18
2015	Bracken, CP, Khew-Goodall, Y & Goodall, GJ 2015, 'Network-based approaches to understand the roles of miR-200 and other microRNAs in cancer', Cancer Research, vol. 75, no. 13, pp. 2594-2599. Open access 50 50 1
2015	Conn, SJ, Pillman, KA, Toubia, J, Conn, VM, Salmanidis, M, Phillips, CA, Roslan, S, Schreiber, AW, Gregory, PA & Goodall, GJ 2015, 'The RNA binding protein quaking regulates formation of circRNAs', Cell, vol. 160, no. 6, pp. 1125-1134. Open access 1621 1582 24
2015	Fisher, JN, Terao, M, Fratelli, M, Kurosaki, M, Paroni, G, Zanetti, A, Gianni, M, Bolis, M, Lupi, M, Tsykin, A, Goodall, GJ & Garattini, E 2015, 'MicroRNA networks regulated by all-trans retinoic acid and Lapatinib control the growth, survival and motility of breast cancer cells', Oncotarget, vol. 6, no. 15, pp. 13176-13200. Open access 34 32
2015	Pal, B, Chen, Y, Bert, A, Hu, Y, Sheridan, JM, Beck, T, Shi, W, Satterley, K, Jamieson, P, Goodall, GJ, Lindeman, GJ, Smyth, GK & Visvader, JE 2015, 'Integration of microRNA signatures of distinct mammary epithelial cell types with their gene expression and epigenetic portraits', Breast Cancer Research, vol. 17, no. 1, article no. 85, pp. 1-16. Open access 29 27
2015	Sanjie, E, Diesch, J, Lesmana, A, Poortinga, G, Hein, N, Lidgerwood, G, Cameron, DP, Ellul, J, Goodall, GJ, Wong, LH, Dhillon, AS, Hamdane, N, Rothblum, L I, Pearson, RB, Haviv, I, Moss, T & Hannan, RD 2015, 'A novel role for the pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed pol II genes', Genome Research, vol. 25, no. 2, pp. 201-212. Open access 44 45
2015	Thomson, DW, Pillman, KA, Anderson, ML, Lawrence, DM, Toubia, J, Goodall, G & Bracken, C 2015, 'Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin', Nucleic Acids Research, vol. 43, no. 1, pp. 470-481. Open access 33 30 2
2015	Yu, F, Bracken, CP, Pillman, KA, Lawrence, DM, Goodall, GJ, Callen, DF & Neilsen, PM 2015, 'p53 represses the oncogenic Sno-MiR-28 derived from a SnoRNA', PLoS One, vol. 10, no. 6, article no. e0129190, pp. 1-20. Open access 57 53 5
2014	Arac, A, Grimbaldeston, MA, Nepomuceno, AR, Olayiwola, O, Pereira, MP, Nishiyama, Y, Tsykin, A, Goodall, GJ, Schlecht, U, Vogel, H, Tsai, M, Galli, SJ, Bliss, TM & Steinberg, GK 2014, 'Evidence that meningeal mast cells can worsen stroke pathology in mice', American Journal of Pathology, vol. 184, no. 9, pp. 2493-2504. Open access 54 55
2014	Bracken, CP, Li, X, Wright, JA, Lawrence, DM, Pillman, KA, Salmanidis, M, Anderson, MA, Dredge, BK, Gregory, PA, Tsykin, A, Neilsen, C, Thomson, DW, Bert, AG, Leerberg, JM, Yap, AS, Jensen, KB, Khew-Goodall, Y & Goodall, GJ 2014, 'Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion', The EMBO Journal, vol. 33, no. 18, pp. 2040-2056. Open access 121 119 13
2014	Carroll, AP, Goodall, GJ & Liu, B 2014, 'Understanding principles of miRNA target recognition and function through integrated biological and bioinformatics approaches', Wiley interdisciplinary reviews. RNA, vol. 5, no. 3, pp. 361-379. 53 50
2014	Kolesnikoff, N, Attema, JL, Roslan, S, Bert, AG, Schwarz, QP, Gregory, PA & Goodall, GJ 2014, 'Specificity Protein 1 (Sp1) maintains basal epithelial expression of the miR-200 family: implications for epithelial-mesenchymal transition', Journal of Biological Chemistry, vol. 289, no. 16, pp. 11194-11205. Open access 59 56
2014	Pham, D, Powell, J, Gliddon, B, Moretti, P, Tsykin, A, Van Der Hoek, M, Kenyon, R, Goodall, G & Pitson, S 2014, 'Enhanced expression of transferrin receptor 1 contributes to oncogenic signalling by sphingosine kinase 1', Oncogene, vol. 33, no. 48, pp. 5559-5568. Open access 25 24
2014	Salmanidis, M, Pillman, K, Goodall, G & Bracken, C 2014, 'Direct transcriptional regulation by nuclear microRNAs', The International Journal of Biochemistry and Cell Biology, vol. 54, pp. 304-311. 43 59
2014	Zafar, A, Wu, F, Hardy, K, Li, J, Tu, WJ, McCuaig, R, Harris, J, Khanna, KK, Attema, J, Gregory, PA, Goodall, GJ, Harrington, K, Dahlstrom, JE, Boulding, T, Madden, R, Tan, A, Milburn, PJ & Rao, S 2014, 'Chromatinized protein kinase C-th directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells', Molecular and Cellular Biology, vol. 34, no. 16, pp. 2961-2980. 31 30 10
2014	Zhang, J, Le, TD, Liu, L, Liu, B, He, J, Goodall, GJ & Li, J 2014, 'Inferring condition-specific miRNA activity from matched miRNA and mRNA expression data', Bioinformatics, v 30, no. 21, pp. 3070-3077. Open access 19 17 3
2013	Attema, JL, Bert, AG, Lim, Y-Y, Kolesnikoff, N, Lawrence, DM, Pillman, KA, Smith, E, Drew, PA, Khew-Goodall, Y, Shannon, F & Goodall, GJ 2013, 'Identification of an enhancer that increases miR-200b~429 gene expression in breast cancer cells', PLoS One, vol. 8, no. 9, pp. 1-15. Open access 20 18
2013	Lim, Y-Y, Wright, JA, Attema, JL, Gregory, PA, Bert, AG, Smith, E, Thomas, D, Lopez, AF, Drew, PA, Khew-Goodall, Y & Goodall, GJ 2013, 'Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem cell-like state', Journal of Cell Science, vol. 126, no. 10, pp. 2256-2266. Open access 170 155
2013	Neilsen, P, Noll, J, Mattiske, S, Bracken, C, Gregory, PA, Schulz, R, Lim, S, Kumar, R, Suetani, R, Goodall, G & Callen, D 2013, 'Mutant p53 drives invasion in breast tumors through up-regulation of miR-155', Oncogene, vol. 32, no. 24, pp. 2992-3000. Open access 146 135
2013	Paterson, EL, Kazenwadel, J, Bert, AG, Khew-Goodall, Y, Ruszkiewicz, A & Goodall, GJ 2013, 'Down-regulation of the miRNA-200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression', Neoplasia, vol. 15, no. 2, pp. 180-191. Open access 146 137
2013	Thomson, DW, Bracken, CP, Szubert, JM & Goodall, GJ 2013, 'On measuring miRNAs after transient transfection of mimics or antisense inhibitors', PLoS One, vol. 8, no. 1, pp. 1-7. Open access 103 101
2012	Ahn, Y-H, Gibbons, DL, Chakravarti, D, Creighton, CJ, Rizvi, ZH, Adams, HP, Pertsemlidis, A, Gregory, PA, Wright, JA, Goodall, GJ, Flores, ER & Kurie, JM 2012, 'ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression', Journal of Clinical Investigation, vol. 122, no. 9, pp. 3170-3183. Open access 138 136
2012	McInnes, N, Sadlon, T, Brown, C, Pederson, S, Beyer, M, Schultze, J, McColl, S, Goodall, G & Barry, S 2012, 'FOXP3 and FOXP3-regulated microRNAs suppress SATB1 in breast cancer cells', Oncogene, vol. 31, no. 8, pp. 1045-1054. Open access 90 83
2012	Neilsen, CT, Goodall, GJ & Bracken, CP 2012, 'IsomiRs - the overlooked repertoire in the dynamic microRNAome', Trends in Genetics, vol. 28, no. 11, pp. 544-549. 376 356
2011	Bracken, CP, Szubert, JM, Mercer, TR, Dinger, ME, Thomson, DW, Mattick, JS, Michael, MZ & Goodall, GJ 2011, 'Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage', Nucleic Acids Research, vol. 39, no. 13, pp. 5658-5668. Open access 68 65
2011	Gregory, PA, Bracken, CP, Smith, E, Bert, AG, Wright, JA, Roslan, S, Morris, M, Wyatt, L, Farshid, G, Lim, Y-Y, Lindeman, GJ, Shannon, MF, Drew, PA, Khew-Goodall, Y & Goodall, GJ 2011, 'An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition', Molecular Biology of the Cell, vol. 22, no. 10, pp. 1686-1698. Open access 487 459
2011	Matsushima, K, Isomoto, H, Yamaguchi, N, Inoue, N, Gregory, PA, Goodall, GJ & Nakao, K and 14 other authors 2011, 'MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells', Journal of Translational Medicine, vol. 9, no. 30, pp. 1-12. Open access 128 121
2011	Thomson, DW, Bracken, CP & Goodall, GJ 2011, 'Experimental strategies for microRNA target identification', Nucleic Acids Research, vol. 39, no. 16, pp. 6845-6853. Open access 469 438
2011	Yang, Y, Ahn, Y-H, Gibbons, DL, Zang, Y, Lin, W, Thilaganathan, N, Alvarez, CA, Moreira, DC, Creighton, C, Gregory, PA, Goodall, GJ & Kurie, JM 2011, 'The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200: dependent pathway in mice', Journal of Clinical Investigation, vol. 121, no. 4, pp. 1373-1385. Open access 175 162
2010	Khew-Goodall, Y & Goodall, GJ 2010, 'Myc-modulated miR-9 makes more metastases', Nature Cell Biology, vol. 12, no. 3, pp. 209-211. 99 97
2010	Mercer, TR, Dinger, ME, Bracken, CP, Kolle, G, Szubert, JM, Korbie, DJ, Askarian-Amiri, ME, Gardiner, BB, Goodall, GJ, Grimmond, SM & Mattick, JS 2010, 'Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome', Genome Research, vol. 20, no. 12, pp. 1639-1650. Open access 73 62
2010	Sadlon, TJ, Wilkinson, BG, Pederson, S, Brown, CY, Bresatz, S, Gargett, T, Melville, EL, Peng, K, D'Andrea, RJ, Glonek, GG, Goodall, GJ, Zola, H, Shannon, MF & Barry, SC 2010, 'Genome-wide identification of human FOXP3 target genes in natural regulatory T cells', Journal of Immunology, vol. 185, no. 2, pp. 1071-1081. Open access 118 117
2010	Terao, M, Fratelli, M, Kurosaki, M, Zanetti, A, Guarnaccia, V, Paroni, G, Tsykin, A, Lupi, M, Gianni, M, Goodall, GJ & Garattini, E 2010, 'Induction of miR-21 by retinoic acid in estrogen receptor-positive breast carcinoma cells: biological correlates and molecular targets', Journal of Biological Chemistry, vol. 286, no. 5, pp. 4027-4042. Open access 88 76
2009	Bracken, C, Gregory, P, Khew-Goodall, Y & Goodall, G 2009, 'The role of microRNAs in metastasis and epithelial-mesenchymal transition', Cellular and Molecular Life Sciences, vol. 66, no. 10, pp. 1682-1699. 107 96
2009	Caruso, M, Moore, J, Goodall, GJ, Thomas, M, Phillis, S, Tyskin, A, Cheetham, G, Lerda, N, Takahashi, H & Ruszkiewicz, A 2009, 'Over-expression of cathepsin E and trefoil factor 1 in sessile serrated adenomas of the colorectum identified by gene expression analysis', Virchows Archiv, vol. 454, no. 3, pp. 291-302. 32 30
2009	Gibbons, DL, Lin, W, Creighton, CJ, Rizvi, ZH, Gregory, PA, Goodall, GJ, Thilaganathan, N, Du, L, Zhang, Y, Pertsemlidis, A & Kurie, J 2009, 'Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression', Genes and Development, vol. 23, no. 18, pp. 2140-2151. Open access 433 412
2009	Powell, JA, Thomas, D, Barry, EF, Kok, CH, McClure, BJ, Tsykin, A, To, LB, Brown, A, Lewis, ID, Herbert, K, Goodall, GJ, Speed, TP, Asou, N, Jacob, B, Osato, M, Haylock, DN, Nilsson, SK, D'Andrea, RJ, Lopez, AF & Guthridge, MA 2009, 'Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML', Blood, vol. 114, no. 23, pp. 4859-4870. 53 51
2008	Bert, A, Prizzi, N, Gregory, PA, Paterson, E, Goodall, G & Khew-Goodall, Y 2008, 'The microRNA-200 Family Regulates Epithelial to Mesenchymal Transition', The Scientific World Journal, vol. 8, pp. 901-904. Open access 76 72
2008	Bracken, CP, Gregory, PA, Kolesnikoff, N, Bert, AG, Wang, J, Shannon, MF & Goodall, GJ 2008, 'A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition', Cancer Research, vol. 68, no. 19, pp. 7846-7854. Open access 928 876
2008	Goodall, G, Farshid, G, Bert, A, Khew-Goodall, Y, Tsykin, A, Vadas, M, Gregory, PA, Paterson, E & Barry, S 2008, 'The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1', Nature Cell Biology, vol. 10, no. 5, pp. 593-601. 3351 3155
2008	Gregory, PA, Bracken, CP, Bert, AG & Goodall, GJ 2008, 'MicroRNAs as regulators of epithelial-mesenchymal transition', Cell Cycle, vol. 7, no. 20, pp. 3112-3117. Open access 435 404

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Australian National University	AUSTRALIA
Bar-Ilan University	ISRAEL
Baylor College of Medicine	UNITED STATES
Canberra Hospital	AUSTRALIA
Cancer Council of South Australia	AUSTRALIA
Central Queensland University	AUSTRALIA
Charles Sturt University	AUSTRALIA
Children's Cancer Institute Australia	AUSTRALIA
Childrens Hospital at Westmead	AUSTRALIA
Dali University	CHINA
Deakin University	AUSTRALIA
Flinders University	AUSTRALIA
Friedrich Miescher Institute for Biomedical Research	SWITZERLAND
Garvan Institute of Medical Research	AUSTRALIA
Ghent University	BELGIUM
Hanson Institute	AUSTRALIA
Harvard University	UNITED STATES
Hudson Institute of Medical Research	AUSTRALIA
Institute of Medical and Veterinary Science	AUSTRALIA
Istituto di Ricerche Farmacologiche Mario Negri	ITALY
Kanazawa University	JAPAN
Kumamoto University	JAPAN
Kunming University of Science and Technology	CHINA
Mahidol University	THAILAND
Memorial Sloan Kettering Cancer Centre	UNITED STATES
Monash University	AUSTRALIA
Monterrey Institute Of Technology And Higher Education	MEXICO
Mount Sinai Hospital	UNITED STATES
Nagasaki University	JAPAN
National University of Singapore	SINGAPORE
Peter MacCallum Cancer Centre	AUSTRALIA
QIMR Berghofer Medical Research Institut	AUSTRALIA
Queensland University of Technology	AUSTRALIA
Royal Brisbane and Women's Hospital	AUSTRALIA
Royal Children's Hospital	UNITED KINGDOM
SA Pathology	AUSTRALIA
Shanghai Jiao Tong University	CHINA
South Australian Health and Medical and Research Institute (SAHMRI)	AUSTRALIA
St Vincent's Hospital	AUSTRALIA
St. Vincent's Institute of Medical Research	AUSTRALIA
Stanford University	UNITED STATES
Sun Yat-Sen University	CHINA
The Institut Pasteur	FRANCE
The Queen Elizabeth Hospital	AUSTRALIA
University Health Network	CANADA
University Libre Bruxelles	BELGIUM
University of Adelaide	AUSTRALIA
University of Arizona	UNITED STATES
University of Basel	SWITZERLAND
University of Bonn	GERMANY
University of British Columbia	CANADA
University of California	UNITED STATES
University of California San Diego	UNITED STATES
University of Canberra	AUSTRALIA
University of Laval	CANADA
University of Malaya	MALAYSIA
University of Melbourne	AUSTRALIA
University of New South Wales	AUSTRALIA
University of Newcastle	AUSTRALIA
University of North Carolina at Chapel Hill	UNITED STATES
University Of Oklahoma Norman	UNITED STATES
University of Pennsylvania	UNITED STATES
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Surrey	UNITED KINGDOM
University of Sydney	AUSTRALIA
University of Texas	UNITED STATES
University of Texas MD Anderson Cancer Centre	UNITED STATES
University of Toronto	CANADA
Walter and Eliza Hall Institute of Medical Research	AUSTRALIA
Women's and Children's Hospital	AUSTRALIA

External engagement & recognition

Engagement/recognition	Year
Fellow Australian Academy of Science	2018
Julian Wells Medal Lorne Genome Conference	2018
Project Grant National Health and Medical Research Council (NHMRC)	2016
Fellow Australian Academy of Health and Medical Science	2015

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
110391 - Oncogenic drivers of neuroblastoma	Current
110423 - Tackling Neuroblastoma using a multi-omics bioinformatics approach	Current
111069 - Illuminating the function of alternative splicing in cancer using CRISPR-based screens	Current
A novel protein ZCCHC24 as a regulator of breast cancer cell plasticity and metastasis	Current
Alternative splicing networks and their impact on the development of aggressive prostate cancer	Current
Nuclear functions of microRNAs that control EMT in breast cancer	Current
Targeting oncogenic signalling with custom RNA drugs	Current
Understanding how the epigenetic field effect exerted by cancers upon their microenvironment promotes tumour progression	Current
Understanding how the epigenetic field effect exerted by cancers upon their microenvironment promotes tumour progression	Current
Computational modelling for breast cancer prognosis in precision medicine	Completed
Developing network inference methods for cancer driver discovery	Completed
Elucidating coding region targets of microRNAs	Completed
The role of RNA-binding proteins in epithelial-mesenchymal transition	Completed

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Professor Greg Goodall

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Chapters

Journal Articles

External engagement & recognition

Collaborations

Collaborations

External engagement & recognition

Fellow

Julian Wells Medal

Project Grant

Fellow

Teaching & student supervision

Courses and programs

Research degree supervision

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