Dr Jantina Manning is an accomplished early career researcher at the Centre for Cancer Biology, University of South Australia, and a tutor for several undergraduate subjects. She has developed and led a research project focused on characterising a new gene, Nedd4-2, in kidney homeostasis, disease and diabetes, resulting in 21 peer reviewed articles in high impact factor journals. Her work has been recognised with grants, fellowships and awards, and she regularly contributes to the scientific community including through peer review and committee leadership.
Research:
Dr Manning's research expertise lies in the study of fundamental molecular and cellular biological processes, animal models and translation into human clinical... Read more
About me
Dr Jantina Manning is an accomplished early career researcher at the Centre for Cancer Biology, University of South Australia, and a tutor for several undergraduate subjects. She has developed and led a research project focused on characterising a new gene, Nedd4-2, in kidney homeostasis, disease and diabetes, resulting in 21 peer reviewed articles in high impact factor journals. Her work has been recognised with grants, fellowships and awards, and she regularly contributes to the scientific community including through peer review and committee leadership.
Research:
Dr Manning's research expertise lies in the study of fundamental molecular and cellular biological processes, animal models and translation into human clinical relevance. You can learn more about her research in the following YouTube videos:
Teaching:
Since 2021, has also been active in delivering first-year tutorials, practicals, workshops and lectures for Human Body 1/2, and Biology A/B at the University of South Australia. Her passion for guiding students and instilling an appetite for learning has driven her to pursue additional teaching roles. She is dedicated to improving her own teaching and scholarship of teaching and learning.
About me
Member of Australia and New Zealand Society for Cell and Development Biology
Member of Australia and New Society of Nephrology
Member of Ausralian Diabetes Society
Associate member of Faculty of 1000 (F1000-Biology)
About me
Doctor of Philosophy The University of Adelaide
Previous Qualifications:
2004 First Class Honours, Department of Physiology, University of Adelaide
2003 B. Biotechnology, University of Adelaide
Identified NEDD4L as a key player in diabetic kidney disease
Discovered NEDD4-2 as an important enzyme in kidney homeostasis
Demonstrated salt-sensitive kidney disease caused by NEDD-2 deficiency
Identified NEDD4 interacting partners important in testes development
Research
Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus
Open access indicates that an output is open access.
| Year | Output |
|---|---|
| 2020 |
Open access
8
8
6
|
| 2018 |
Open access
55
58
1
|
| 2017 |
Open access
27
28
2
|
| 2015 |
Open access
133
135
1
|
| Year | Output |
|---|---|
| 2025 |
Open access
|
| 2024 |
Open access
3
1
7
|
| 2024 |
Open access
2
1
3
|
| 2023 |
Open access
1
2
|
| 2022 |
Open access
10
9
2
|
| 2021 |
Open access
13
12
112
|
| 2021 |
Open access
10
11
2
|
| 2020 |
Open access
8
8
6
|
| 2020 |
2
2
4
|
| 2018 |
Open access
55
58
1
|
| 2017 |
Open access
27
28
2
|
| 2015 |
Open access
133
135
1
|
| 2014 |
Open access
33
32
|
| 2010 |
Open access
29
31
|
| 2010 |
Open access
13
13
|
| 2010 |
Open access
39
39
|
| 2008 |
14
15
|
The enzyme that could help 700 million people with chronic kidney disease
https://www.youtube.com/watch?v=Szi0YW0-ZdU
How genetics plays a role in kidney disease:
https://www.youtube.com/watch?v=rN-Yf2XeVzA&pp=ygUVamFudGluYSBtYW5uaW5nIHVuaXNh
Research
Identified NEDD4L as a key player in diabetic kidney disease
Discovered NEDD4-2 as an important enzyme in kidney homeostasis
Demonstrated salt-sensitive kidney disease caused by NEDD-2 deficiency
Identified NEDD4 interacting partners important in testes development
Presenter, Pint of Science, 2024
Diabetes Australia Grant, 2023
Diabetes SA Research Grant, 2024-2025
Early Career Researcher Award for Cell Biology (Australia and New Zealand Society for Cell and Developmental Biology), 2019
Sparrho Early Career Researcher Prize, 2018
External engagement & recognition
| Organisation | Country |
|---|---|
| Austin Research Institute | AUSTRALIA |
| Hudson Institute of Medical Research | AUSTRALIA |
| La Trobe University | AUSTRALIA |
| Max Planck Institute of Experimental Medicine | GERMANY |
| Mercy Hospital for Women | AUSTRALIA |
| Queensland University of Technology | AUSTRALIA |
| SA Pathology | AUSTRALIA |
| University of Adelaide | AUSTRALIA |
| University of Melbourne | AUSTRALIA |
| University of Otago | NEW ZEALAND |
| University of South Australia | AUSTRALIA |
| University of Sydney | AUSTRALIA |
| Walter and Eliza Hall Institute of Medical Research | AUSTRALIA |
External engagement & recognition
| Engagement/recognition | Year |
|---|---|
Best Postdoctoral Talk AwardAustralia and New Zealand Society for Cell and Developmental Biology |
2024 |
Most Outstanding Postdoctoral Oral PresentationAustralia and New Zealand Society for Cell and Developmental Biology |
2022 |
Early-Career Researcher Award (Cell Biology)Australia and New Zealand Society for Cell and Developmental Biology |
2019 |
Mary Overton Early Career FellowshipRoyal Adelaide Hospital |
2017 |
Runner up, Postgraduate Poster Award7th Australia and New Zealand Society for Cell and Developmental Biology (ANZSCDB) Meeting, Adelaide |
2017 |
invited Presentation6th Australia and New Zealand Society for Cell and Developmental Biology Meeting, Adelaide |
2016 |
Mary Overton Early Career FellowshipRoyal Adelaide Hospital |
2016 |
Mary Overton Early Career FellowshipRoyal Adelaide Hospital |
2015 |
Mary Overton Early Career FellowshipRoyal Adelaide Hospital |
2014 |
Mary Overton Early Career FellowshipRoyal Adelaide Hospital |
2013 |
Mary Overton Early Career FellowshipRoyal Adelaide Hospital |
2012 |
Mary Overton Early Career FellowshipRoyal Adelaide Hospital |
2011 |
Teaching & student supervision
Teaching & student supervision
Supervisions from 2010 shown
| Thesis title | Student status |
|---|---|
| Investigating the functions of the ubiquitin ligase NEDD4-2 in kidney disease. | Current |
| Modulation of NEDD4-2 expression and activity as a cellular mechanism for ameliorating kidney disease | Current |
| Regulation of autophagy in cell and tissue homeostasis | Current |
| Analysis of Arrdc4 ubiquitination and its function in extracellular vesicles biogenesis | Completed |
