Jason White is an Adjunct Professor in the School of Pharmacy and Medical Sciences, University of South Australia. He qualified from the University of Adelaide with a BSc (Hons) and a PhD, received post-doctoral training in pharmacology at Emory University and subsequently held academic positions at Monash University, the University of Adelaide and at the University of South Australia from 2010 to 2018 as Professor of Pharmacology and Head of the School of Pharmacy and Medical Sciences. Prof White has published extensively in the pharmacology of addictive drugs and in the treatment of drug and alcohol dependence, and attracted numerous research grants and contracts from NHMRC, NIH, government and industry. In... Read more
About me
Jason White is an Adjunct Professor in the School of Pharmacy and Medical Sciences, University of South Australia. He qualified from the University of Adelaide with a BSc (Hons) and a PhD, received post-doctoral training in pharmacology at Emory University and subsequently held academic positions at Monash University, the University of Adelaide and at the University of South Australia from 2010 to 2018 as Professor of Pharmacology and Head of the School of Pharmacy and Medical Sciences. Prof White has published extensively in the pharmacology of addictive drugs and in the treatment of drug and alcohol dependence, and attracted numerous research grants and contracts from NHMRC, NIH, government and industry. In addition to research and teaching, he has extensive experience in the treatment of people with alcohol and drug problems, in the management of clinics providing such treatment, and in the provision of expert evidence related to drug effects in civil and criminal matters. He is currently Chair of the World Health Organization Expert Committee on Drug Dependence.
About me
Australasian Professional Society on Alcohol and Other Drugs (Secretary 1992-1996, Vice President 1996-1998, President 1998-2000, Past-president 2000-2002, Convenor 1997 National Conference)
College on Problems of Drug Dependence (Member, International Committee, 1996-1999, 2004-2007)
Member, Committee on the Abuse Liability of Drugs, College on Problems of Drug Dependence (2016-current)
Australian Society for Clinical and Experimental Pharmacologists and Toxicologists
About me
Doctor of Philosophy University of Adelaide
Bachelor of Science (Honours) University of Adelaide
My research focuses on the pharmacology of drugs of dependence, particularly opioids and stimulants. We have a laboratory to measure physiological, behavioural and cognitive function in human subjects, both volunteers and clinical populations. The clinical groups include people being treated for drug dependence and pain patients who are prescribed opioids. We also conduct clinical trials in these populations at treatment centres in Adelaide.Our research has two main aims. The first is to characterise the adverse effects of long term use of opioids and stimulant drugs. For example, we have shown that prolonged opioid use in the context of either pain treatment or addiction increases sensitivity to some types of painful stimuli. This... Read more
Research
Excludes commercial-in-confidence projects.
Randomised double-blind placebo-controlled study of lisdexamfetamine for the treatment of methamphetamine dependence, NHMRC - Project Grant, 01/01/2016 - 31/12/2021
Daily sampling at an agreed South Australian regional wastewater treatment plant, Australian Criminal Intelligence Commission, 15/03/2021 - 30/06/2021
Prison Wastewater Sampling and Analysis, SA Dept for Correctional Services, 11/08/2020 - 07/02/2021
Tracking use of novel psychoactive substances in Australia, Thyne Reid Foundation, 20/06/2017 - 31/01/2020
National Waste Water Analysis Pilot, Australian Criminal Intelligence Commission, 01/01/2017 - 30/12/2019
Are young adults aware of the long-lasting consequences of methamphetamine ('ICE') use on all health & would knowledge of a visible long-lasting consequence decrease use of the drug?, Fay Fuller Foundation, 06/03/2017 - 30/06/2019
Waste water analysis to test methamphetamine usage levels, Western Australia Police, 01/08/2015 - 02/08/2018
Research Infrastructure Fund (RIF) Grant 2016 Round 2 - Biofilm Testing Facility, Adelaide Integrated Bioscience Laboratories, 28/11/2016 - 31/12/2017
Waste water analysis to test metabolites of a variety of drugs, Southern Adelaide Health Service, 01/10/2015 - 18/12/2017
Randomised double-blind placebo-controlled study of lisdexamfetamine for the treatment of methamphetamine dependence, NHMRC - Project Grant, 2016-2019
Research
Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID, ResearcherID or Scopus
Open access indicates that an output is open access.
Year | Output |
---|---|
2023 |
1
1
|
2017 |
1
9
|
2016 |
1
|
2009 |
|
2009 |
|
2009 |
|
2009 |
|
Year | Output |
---|---|
2024 |
Open access
2
92
|
2024 |
Open access
2
|
2024 |
Open access
514
|
2023 |
Open access
25
22
102
|
2023 |
3
4
1
|
2023 |
Open access
3
4
30
|
2023 |
Open access
4
4
89
|
2022 |
31
28
101
|
2022 |
Open access
2
4
|
2022 |
6
5
1
|
2022 |
9
7
18
|
2021 |
5
5
2
|
2021 |
Open access
58
53
33
|
2021 |
25
23
40
|
2021 |
Open access
13
11
5
|
2021 |
36
31
124
|
2021 |
19
15
1
|
2021 |
9
7
1
|
2021 |
Open access
3
3
|
2021 |
4
2
58
|
2020 |
Open access
5
4
15
|
2020 |
61
54
6
|
2020 |
Open access
28
25
1
|
2020 |
Open access
13
11
5
|
2020 |
Open access
39
34
75
|
2020 |
Open access
12
9
|
2020 |
Open access
|
2020 |
40
37
3
|
2020 |
18
19
1
|
2019 |
Open access
26
25
|
2019 |
Open access
36
33
4
|
2019 |
Open access
31
26
3
|
2019 |
Open access
58
48
1
|
2019 |
Open access
4
|
2019 |
Open access
6
4
8
|
2019 |
3
2
2
|
2019 |
201
175
|
2019 |
Open access
4
4
6
|
2019 |
5
4
9
|
2018 |
Open access
16
13
2
|
2018 |
39
35
3
|
2018 |
Open access
13
10
|
2018 |
Open access
17
17
|
2018 |
Open access
63
59
5
|
2018 |
Open access
71
55
|
2017 |
Open access
36
16
|
2017 |
Open access
120
98
|
2017 |
|
2017 |
Open access
22
22
8
|
2017 |
12
11
61
|
2016 |
Open access
93
112
|
2016 |
10
9
|
2016 |
3
2
|
2016 |
Open access
3
3
|
2016 |
Open access
32
29
42
|
2016 |
118
106
54
|
2016 |
35
31
10
|
2015 |
6
6
1
|
2015 |
|
2015 |
36
37
1
|
2014 |
125
111
|
2014 |
Open access
82
29
|
2014 |
Open access
7
7
1
|
2013 |
Open access
51
44
|
2013 |
8
7
|
2013 |
8
5
|
2013 |
Open access
43
39
|
2012 |
Open access
47
42
|
2012 |
54
49
|
2012 |
Open access
21
17
|
2012 |
Open access
104
96
|
2012 |
Open access
24
19
|
2012 |
Open access
19
17
|
2012 |
Open access
27
24
|
2012 |
Open access
11
11
|
2012 |
6
4
|
2012 |
Open access
1
|
2012 |
Open access
27
|
2012 |
17
15
|
2012 |
20
17
|
2011 |
17
15
|
2011 |
39
33
|
2011 |
Open access
130
125
|
2011 |
12
12
|
2011 |
54
49
|
2010 |
15
13
|
2010 |
101
85
|
2010 |
Open access
5
4
|
2010 |
94
78
|
2010 |
48
42
|
2009 |
135
112
|
2009 |
41
37
|
2009 |
63
53
|
2008 |
157
152
|
2008 |
Open access
18
19
|
2008 |
33
26
|
2008 |
67
55
|
2008 |
40
36
|
2008 |
27
18
|
2008 |
Open access
103
92
|
2008 |
18
14
|
2008 |
11
8
|
Year | Output |
---|---|
2024 |
Open access
|
2023 |
Open access
|
2023 |
Open access
|
2023 |
Open access
|
2022 |
Open access
|
2022 |
Open access
|
2022 |
Open access
|
2021 |
Open access
|
2019 |
Open access
|
2019 |
Open access
|
2018 |
Open access
|
2018 |
Open access
|
2017 |
Open access
|
2017 |
Open access
|
2017 |
Open access
|
2017 |
Open access
|
Research
My research focuses on the pharmacology of drugs of dependence, particularly opioids and stimulants. We have a laboratory to measure physiological, behavioural and cognitive function in human subjects, both volunteers and clinical populations. The clinical groups include people being treated for drug dependence and pain patients who are prescribed opioids. We also conduct clinical trials in these populations at treatment centres in Adelaide.Our research has two main aims. The first is to characterise the adverse effects of long term use of opioids and stimulant drugs. For example, we have shown that prolonged opioid use in the context of either pain treatment or addiction increases sensitivity to some types of painful stimuli. This opioid-induced hyperalgesia may play an important role in maintaining long term patterns of opioid use. In future research we will examining the factors that predict the degree of hyperalgesia (eg pharmacogenetic factors) and pharmacological strategies to reduce hyperalgesia. Another project involves collaboration with cognitive psychologists to characterise the impairment in function arising from chronic opioid use and the relative effects of partial and full agonists. The second aim is to improve current treatments for drug dependence and pain. Several strategies are being used. One is to improve medication adherence and reduce the variation due to pharmacokinetics by using long acting formulations of drugs currently employed in treatment. For example, we conducted the first trial of a buprenorphine implant that provided therapeutic concentrations of the drug over a 6 month period. A second strategy has been to trial novel drug combinations. For example, we showed the efficacy of combinations of buprenorphine with ultra-low doses of opioid antagonists. This was the first definitive study to demonstrate that a combination shown in animal models to reduce opioid requirements and decrease the development of tolerance was also effective in humans. We have also used pharmacogenetic approaches to examine how opioids can best be used to minimise risks of dependence.
External engagement & recognition
Organisation | Country |
---|---|
Allwater | AUSTRALIA |
Arizona State University | UNITED STATES |
Association of Child Care Centres of SA Inc | AUSTRALIA |
Centre for Treatment of Anxiety Disorders | AUSTRALIA |
Chiang Mai University | THAILAND |
Curtin University | AUSTRALIA |
Dalian Maritime University | CHINA |
Department of Defence | AUSTRALIA |
Drug and Alcohol Services SA | AUSTRALIA |
ESR - Christchurch Science Centre | NEW ZEALAND |
European Monitoring Centre on Drugs and Drug Addiction | PORTUGAL |
Flinders Medical Centre | AUSTRALIA |
Flinders University | AUSTRALIA |
Forensic Science SA | AUSTRALIA |
Ghent University | BELGIUM |
Goethe University Frankfurt | GERMANY |
Grenoble Alpes University | FRANCE |
Griffith University | AUSTRALIA |
Hunter New England Population Health | AUSTRALIA |
Institute of Environmental Science and Research | NEW ZEALAND |
Istituto di Ricerche Farmacologiche Mario Negri | ITALY |
Jaume I University | SPAIN |
King's College London | UNITED KINGDOM |
KWPX | AUSTRALIA |
KWR Water Research Institute | NETHERLANDS |
Lyell McEwin Hospital | AUSTRALIA |
Monash University | AUSTRALIA |
National Drug and Alcohol Research Centre | AUSTRALIA |
National Institute on Drug Abuse | UNITED STATES |
Neuroscience Research Australia | AUSTRALIA |
Norwegian Institute for Water Research | NORWAY |
Queensland Health | AUSTRALIA |
Queensland University of Technology | AUSTRALIA |
Royal Adelaide Hospital | AUSTRALIA |
Royal Brisbane and Women's Hospital | AUSTRALIA |
SA Pathology | AUSTRALIA |
South Western Sydney Area Health Service | AUSTRALIA |
St Vincent's Hospital | AUSTRALIA |
The Byrne Surgery, Specialist Drug and Alcohol Practice, Redfern, New South Wales | AUSTRALIA |
The Queen Elizabeth Hospital | AUSTRALIA |
Titan Pharmaceuticals | UNITED STATES |
Universitat Jaume I | SPAIN |
University of Adelaide | AUSTRALIA |
University of Antwerp | BELGIUM |
University of Auckland | NEW ZEALAND |
University of California | UNITED STATES |
University of Colorado Denver | UNITED STATES |
University of Copenhagen | DENMARK |
University of Kuopio | FINLAND |
University of Melbourne | AUSTRALIA |
University of New South Wales | AUSTRALIA |
University of Newcastle | AUSTRALIA |
University of Puget Sound | UNITED STATES |
University of Queensland | AUSTRALIA |
University of Shahrekord | IRAN |
University of South Australia | AUSTRALIA |
University of Sydney | AUSTRALIA |
University of Tasmania | AUSTRALIA |
University of Tubingen | GERMANY |
University of Utah | UNITED STATES |
Walter Reed Army Institute for Research | UNITED STATES |
Western Sydney Local Health District | AUSTRALIA |
Women's and Children's Hospital | AUSTRALIA |
World Health Organisation | SWITZERLAND |
Yah Yah | AUSTRALIA |
Teaching & student supervision
Supervisions from 2010 shown
Thesis title | Student status |
---|---|
- Non target and suspect screening of compounds of concern in influent and effluent wastewater | Current |
Addressing the challenges for measuring population biomarkers and cannabinoids by wastewater-based epidemiology | Completed |
Investigation of peripheral biomarkers for assessing operator alertness and attention during sleep loss | Completed |
Population-scale drug use in Adelaide, South Australia, by wastewater analysis | Completed |
Spatiotemporal study of stress biomarkers and benzodiazepines in Australian wastewater | Completed |
The impact of genetic predictors of opioid dependence on neuroimmune and endocrine markers in healthy adults | Completed |
The long-term effect of illicit stimulant use on movement | Completed |