Doctor of Philosophy China Agricultural University
Excludes commercial-in-confidence projects.
Preclinical Studies of MUC1 Targeted Alpha Therapy in Pancreatic Cancer, Avner Pancreatic Cancer Foundation, 25/10/2019 - 04/12/2020
Open access indicates that an output is open access.
Gummow, J, Masavuli, MG, Mekonnen, ZA, Li, Y, Wijesundara, DK, Shrestha, AC, Voskoboinik, I, Gowans, EJ & Grubor-Bauk, B 2020, 'Safety profile of a multi-antigenic DNA vaccine against hepatitis C virus', Vaccines, vol. 8, no. 1, article no. 53, pp. 1-14.
Staudacher, AH, Li, Y, Liapis, V, Hou, JJC, Chin, D, Dolezal, O, Adams, TE, van Berkel, PH & Brown, MP 2019, 'APOMAB antibody-drug conjugates targeting dead tumor cells are effective in vivo', Molecular Cancer Therapeutics, vol. 18, no. 2, pp. 335-345.
4 4 1
Reid, P, Wilson, P, Li, Y, Marcu, LG, Staudacher, AH, Brown, MP & Bezak, E 2018, 'Experimental investigation of radiobiology in head and neck cancer cell lines as a function of HPV status, by MTT assay', Scientific Reports, vol. 8, article no. 7744, pp. 1-7.
Open access 7 7 10
Wijesundara, DK, Gummow, J, Li, Y, Yu, W, Quah, BJ, Ranasinghe, C, Torresi, J, Gowans, EJ & Grubor-Bauk, B 2018, 'Induction of genotype cross-reactive, hepatitis C virus-specific, cellmediated immunity in DNA-vaccinated mice', Journal of Virology, vol. 92, no. 8, article no. e02133-17, pp. 1-15.
Open access 12 13 2
Reid, P, Wilson, P, Li, Y, Marcu, LG, Staudacher, AH, Brown, MP & Bezak, E 2017, 'In vitro investigation of head and neck cancer stem cell proportions and their changes following x-ray irradiation as a function of HPV status', PLoS One, vol. 12, no. 10, article no. e0186186, pp. 1-16.
Open access 11 10 3
Reid, PA, Wilson, P, Li, Y, Marcu, LG & Bezak, E 2017, 'Current understanding of cancer stem cells: review of their radiobiology and role in head and neck cancers', Head and Neck, vol. 39, no. 9, pp. 1920-1932.
17 17 1
Al, DR, Staudacher, A, Li, Y, Brown, M & Bezak, E 2016, 'Development of a transmission alpha particle dosimetry technique using A549 cells and a Ra-223 source for targeted alpha therapy', Medical Physics, vol. 43, no. 11, pp. 6145-6153.
5 4 1
Tomusange, K, Wijesundara, D, Gummow, J, Garrod, T, Li, Y, Gray, L, Churchill, M, Grubor-Bauk, B & Gowans, EJ 2016, 'A HIV-Tat/C4-binding protein chimera encoded by a DNA vaccine is highly immunogenic and contains acute EcoHIV infection in mice', Scientific Reports, vol. 6, no. 1, pp. 1-10.
Open access 12 12 1
Gummow, J, Yanrui, L, Wenbo, Y, Garrod, T, Wijesundara, D, Brennan, AJ, Mullick, R, Voskoboinik, I, Grubor-Bauk, B & Gowansa, EJ 2015, 'A multiantigenic DNA vaccine that induces broad hepatitis C virus-specific T-Cell responses in mice', Journal of Virology, vol. 89, no. 15, pp. 7991-8002.
Open access 14 17 1
Garrod, TJ, Bruber-Bauk, B, Gargett, T, Li, Y, Miller, DS, Wenbo, Y, Major, L, Burrell, CJ, Wesselingh, S, Suhrbier, A & Gowans, EJ 2014, 'DNA vaccines encoding membrane-bound or secreted forms of heat shock protein 70 exhibit improved potency', European Journal of Immunology, vol. 44, no. 7, pp. 1992-2002.
Open access 18 16 1
Li, J, Li, Y, Jiao, J, Wang, J, Li, Y, Qin, D & Li, P 2014, 'Mitofusin 1 is negatively regulated by MicroRNA 140 in cardiomyocyte apoptosis', Molecular and Cellular Biology, vol. 34, no. 10, pp. 1788-1799.
Wang, J-X, Jiao, J-Q, Li, Q, Long, B, Wang, K, Liu, J-P, Li, Y-R & Li, P-F 2011, 'miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1', Nature Medicine, vol. 17, no. 1, pp. 71-78.
414 393 2
Li, J, Donath, S, Li, Y, Qin, D, Prabhakar, BS & Li, P 2010, 'miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway', PLoS Genetics, vol. 6, no. 1, article no. e1000795, pp. 1-13.
Open access 261 243
Li, J, Li, Y, Qin, D, von Harsdorf, R & Li, P 2010, 'Mitochondrial fission leads to Smac/DIABLO release quenched by ARC', Apoptosis: An International Journal on Programmed Cell Death, vol. 15, no. 10, pp. 1187-1196.
Li, Y, Zhang, G, Ng, TB & Wang, H 2010, 'A novel lectin with antiproliferative and HIV-1 reverse transcriptase inhibitory activities from dried fruiting bodies of the monkey head mushroom hericium erinaceum', BioMed Research International, vol. 2010, article no. 716515, pp. 1-9.
Open access 51 17
Li, Y, Liu, Q, Wang, H & Ng, T 2008, 'A novel lectin with potent antitumor, mitogenic and HIV-1 reverse transcriptase inhibitory activities from the edible mushroom Pleurotus citrinopileatus', Biochimica et Biophysica Acta (BBA): General Subjects, vol. 1780, no. 1, pp. 51-57.
Tan, W-Q, Wang, J-X, Lin, Z-Q, Li, Y-R, Lin, Y & Li, P-F 2008, 'Novel cardiac apoptotic pathway the dephosphorylation of apoptosis repressor with caspase recruitment domain by calcineurin', Circulation, vol. 118, no. 22, pp. 2268-2276.
External engagement & recognition
|Australian National University||AUSTRALIA|
|China Agricultural University||CHINA|
|Chinese Academy of Sciences||CHINA|
|Chinese University of Hong Kong||HONG KONG|
|CSIRO Australia (Commonwealth Scientific Industrial Research Organisation)||AUSTRALIA|
|HELIOS Clinics GmBH||GERMANY|
|Indian Institute of Science||INDIA|
|Peter MacCallum Cancer Centre||AUSTRALIA|
|PLA General Hospital||CHINA|
|Queensland Institute of Medical Research||AUSTRALIA|
|Royal Adelaide Hospital||AUSTRALIA|
|Royal Australasian College of Surgeons||AUSTRALIA|
|South Australian Health and Medical Research Institute (SAHMRI)||AUSTRALIA|
|Toronto General Research Institute||CANADA|
|University of Adelaide||AUSTRALIA|
|University of Illinois at Chicago||UNITED STATES|
|University of Melbourne||AUSTRALIA|
|University of Nebraska Medical Center||UNITED STATES|
|University of Queensland||AUSTRALIA|
|University of South Australia||AUSTRALIA|
Supervisions from 2010 shown
|Thesis title||Student status|
|Pre-Clinical Studies and Phase I Clinical Trial of MUC1 Targeted Alpha Therapy for Pancreatic Cancer||Current|
|Experimental investigation of in-vitro cancer stem cells in head and neck cancer cell lines following x-ray irradiation||Completed|