Dr Kim Botting-Lawford

Adjunct Research Fellow UniSA Clinical & Health Sciences

City East Campus ()
tel +61 8 830 20189

email Kim.Botting-Lawford@unisa.edu.au

Research

Research focus

Paediatrics and Reproductive Medicine
Clinical Sciences
Biological Sciences
Medical Physiology
Medical and Health Sciences

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included.

Open access indicates that an output is open access.

Journal Articles

Year	Output
2025	Amanollahi, R, Holman, SL, Meakin, AS, Padhee, M, Botting-Lawford, KJ, Zhang, S, Maclaughlin, SM, Kleemann, DO, Walker, SK, Kelly, JM, Rudiger, SR, Mcmillen, IC, Wiese, MD, Lock, MC & Morrison, JL 2025, 'In vitro embryo culture impacts heart mitochondria in male adolescent sheep', JOURNAL OF DEVELOPMENTAL BIOLOGY, vol. 13, no.2, article no. 17, pp. 1-20. Open access
2024	Zhang, S, Lock, MC, Tie, M, McMillen, IC, Botting, KJ & Morrison, JL 2024, 'Cardiac programming in the placentally restricted sheep fetus in early gestation', The Journal of Physiology, vol. 602, no. 15, pp. 3815-3832. Open access 2 2
2023	Padhee, M, Lock, MC, McMillen, IC, Zhang, S, Botting, KJ, Nyengaard, JR, MacLaughlin, SM, Kleemann, DO, Walker, SK, Kelly, JM, Rudiger, SR & Morrison, JL 2023, 'Sex-specific effects of in vitro culture and embryo transfer on cardiac growth in sheep offspring', Journal of Molecular and Cellular Cardiology Plus, vol. 5, article no. 100039, pp. 1-12. Open access 2 6
2018	Botting, K, Loke, X, Zhang, S, Andersen, J, Nyengaard, J & Morrison, J 2018, 'IUGR decreases cardiomyocyte endowment and alters cardiac metabolism in a sex-and cause-of-IUGR-specific manner', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol.315, no. 1, pp. R48-R67. Open access 49 46 1
2018	Lock, MC, Tellam, RL, Botting, KJ, Wang, KC, Selvanayagam, JB, Brooks, DA, Seed, M & Morrison, JL 2018, 'The role of miRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults', The Journal of Physiology, vol. 596, no. 23, pp. 5625-5640. Open access 43 37 3
2017	Lock, MC, Botting, KJ, Tellam, RL, Brooks, D & Morrison, JL 2017, 'Adverse intrauterine environment and cardiac miRNA expression', International Journal of Molecular Sciences, vol. 18, no. 12, article no. 2628 pp. 1-19. Open access 25 23 2
2017	Wang, KC, Botting, KJ, Zhang, S, McMillen, IC, Brooks, DA & Morrison, JL 2017, 'Akt signaling as a mediator of cardiac adaptation to low birth weight', Journal of Endocrinology, vol. 233, no. 2, pp. R81-R94. Open access 17 18 1
2016	Zhang, S, Barker, P, Botting, KJ, Roberts, CT, McMillan, CM, McMillen, IC & Morrison, JL 2016, 'Early restriction of placental growth results in placental structural and gene expression changes in late gestation independent of fetal hypoxemia', Physiological Reports, vol. 4, no. 23, article no. e13049, pp. 1-19. Open access 41 23 2
2015	Morrison, JL, Zhang, S, Tellam, RL, Brooks, DA, McMillen, C, Porrello, E & Botting, K 2015, 'Regulation of microRNA during cardiomyocyte maturation in sheep', BMC Genomics, vol. 16, pp. 1-15. Open access 17 21 4
2015	Orgeig, S, McGillick, E V, Botting, KJ, Zhang, S, McMillen, IC & Morrison, JL 2015, 'Increased lung prolyl hydroxylase and decreased glucocorticoid receptor are related to decreased surfactant protein in the growth-restricted sheep fetus', American Journal of Physiology: Lung Cellular and Molecular Physiology, vol. 309, no. 1, pp. L84-L97. Open access 39 33 1
2015	Padhee, M, Zhang, S, Lie, S, Wang, KC, Botting, KJ, McMillen, C, MacLaughlin, SM & Morrison, JL 2015, 'The periconceptional environment and cardiovascular disease: does in vitro embryo culture and transfer influence cardiovascular development and health', Nutrients, vol. 7, no. 3, pp. 1378-1425. Open access 33 34
2015	Wang, KC, Brooks, DA, Summers-Pearce, B, Bobrovskaya, L, Tosh, DN, Duffield, JA, Botting, KJ, Zhang, S, McMillen, C & Morrison, JL 2015, 'Low birth weight activates the renin-angiotensin system, but limits cardiac angiogenesis in early postnatal life', Physiological Reports, vol. 3, no. 2, article no. e12270, pp. 1-16. Open access 23 16 1
2015	Zhang, S, Regnault, TR, Barker, PL, Botting, KJ, McMillen, IC, McMillan, CM, Roberts, CT & Morrison, JL 2015, 'Placental adaptations in growth restriction', Nutrients, vol. 7, no. 1, pp. 360-389. Open access 191 173 1
2014	Botting, KJ, McMillen, IC, Forbes, H, Nyengaard, JR & Morrison, JL 2014, 'Chronic hypoxemia in late gestation decreases cardiomyocyte number but does not change expression of hypoxia-responsive genes', Journal of the American Heart Association, vol. 3, no. e000531, pp. 1-14. Open access 96 91
2014	Lee, AM, Morrison, JL, Botting, KJ, Shandala, T & Xian, CJ 2014, 'Effects of maternal hypoxia during pregnancy on bone development in offspring : a guinea pig model', International Journal of Endocrinology, vol. 2014, article no. 916918, pp. 1-12. Open access 9 9
2014	Lie, S, Hui, M, McMillen, IC, Muhlhausler, BS, Posterino, GS, Dunn, SL, Wang, KC, Botting, KJ & Morrison, JL 2014, 'Exposure to rosiglitazone, a PPAR-γ agonist, in late gestation reduces the abundance of factors regulating cardiac metabolism and cardiomyocyte size in the sheep fetus', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol. 306, no. 6, pp. R429-R437. Open access 18 18
2012	Botting, K, Wang, K, Padhee, M, McMillen, I, Pearce, B, Rattanatray, L, Cutri, N, Posterino, G, Brooks, D & Morrison, J 2012, 'Early origins of heart disease: low birth weight and determinants of cardiomyocyte endowment', Clinical and Experimental Pharmacology and Physiology, vol. 39, no. 9, pp. 814-823. Open access 74 71
2012	Morrison, JL, Botting, KJ, Soo, PS, McGillick, E V, Hiscock, J, Zhang, S, McMillen, IC & Orgeig, S 2012, 'Antenatal steroids and the IUGR fetus: are exposure and physiological effects on the lung and cardiovascular system the same as in normally grown fetuses?', Journal of Pregnancy, vol. 2012, article no. 839656, pp. 1-15. Open access 73 44
2012	Soo, PS, Hiscock, J, Botting, KJ, Roberts, CT, Davey, AK & Morrison, JL 2012, 'Maternal undernutrition reduces P-glycoprotein in guinea pig placenta and developing brain in late gestation', Reproductive Toxicology, vol. 33, no. 3, pp. 374-381. 77 75
2012	Wang, KC, Brooks, DA, Botting, KJ & Morrison, JL 2012, 'IGF-2R-mediated signaling results in hypertrophy of cultured cardiomyocytes from fetal sheep', Biology of Reproduction, vol. 86, no. 6, pp. 1-8. Open access 11 26
2012	Wang, KCW, Botting, KJ, Padhee, M, Zhang, S, McMillen, IC, Suter, C, Brooks, D & Morrison, JL 2012, 'Early origins of heart disease : low birth weight and the role of the insulin-like growth factor system in cardiac hypertrophy', Clinical and Experimental Pharmacology and Physiology, vol. 39, no. 11, pp. 958-964. Open access 21 19
2011	Posterino, GS, Dunn, SL, Botting, KJ, Wang, W, Gentili, S & Morrison, JL 2011, 'Changes in cardiac troponins with gestational age explain changes in cardiac muscle contractility in the sheep fetus', Journal of Applied Physiology, vol. 111, no. 1, pp. 236-243. Open access 18 16
2011	Wang, KC, Zhang, L, McMillen, IC, Botting, KJ, Duffield, JA, Zhang, S, Suter, C, Brooks, DA & Morrison, JL 2011, 'Fetal growth restriction and the programming of heart growth and cardiac insulin-like growth factor 2 expression in the lamb', The Journal of Physiology, vol. 589, no. 19, pp. 4709-4722. Open access 76 76
2010	Nguyen, LT, Muhlhausler, B, Botting, KJ & Morrison, JL 2010, 'Maternal undernutrition alters fat cell size distribution, but not lipogenic gene expression, in the visceral fat of the late gestation guinea pig fetus', Placenta, vol. 31, no. 10, pp. 902-909. 23 22

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Aarhus University	DENMARK
CSIRO Australia (Commonwealth Scientific Industrial Research organisation)	AUSTRALIA
Flinders University	AUSTRALIA
La Trobe University	AUSTRALIA
South Australian Research and Development Institute (SARDI)	AUSTRALIA
The Hospital for Sick Children	CANADA
University of Adelaide	AUSTRALIA
University of Auckland	NEW ZEALAND
University of Cambridge	UNITED KINGDOM
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
Victor Chang Cardiac Research Institute	AUSTRALIA
Western University	CANADA

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Dr Kim Botting-Lawford

About me

About me

UniSA Clinical & Health Sciences

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Journal Articles

External engagement & recognition

Collaborations

Collaborations

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