Dr Kristen Bremmell

Senior Lecturer in Pharmaceutical Science UniSA Clinical & Health Sciences

City West Campus (HB5-26)
tel +61 8 830 22311

email Kristen.Bremmell@unisa.edu.au

Research Degree Supervisor

Research

Research themes

Healthy futures

Research focus

Chemical Engineering
Chemical Sciences
Engineering
Physical Sciences
Biomedical Engineering

Research

Outputs

Research since 2008 is shown below. To see earlier years visit ORCID, ResearcherID or Scopus

Open access indicates that an output is open access.

Highlights

Year	Output
2019	Bremmell, KE & Prestidge, CA 2019, 'Enhancing oral bioavailability of poorly soluble drugs with mesoporous silica based systems: opportunities and challenges', Drug Development and Industrial Pharmacy, vol. 45, no. 3, pp. 349-358. Open access 17 18
2019	Bremmell, KE, Briskey, D, Meola, TR, Mallard, A, Prestidge, CA & Rao, A 2019, 'A self-emulsifying Omega-3 ethyl ester formulation (AquaCelle) significantly improves eicosapentaenoic and docosahexaenoic acid bioavailability in healthy adults', European Journal of Nutrition, online, pp. 1-9. 1 21
2017	Chang, PK, Prestidge, CA & Bremmell, KE 2017, 'Interfacial analysis of siRNA complexes with poly-ethylenimine (PEI) or PAMAM dendrimers in gene delivery', Colloids and Surfaces B: Biointerfaces, vol. 158, pp. 370-378. Open access 5 3
2016	Chang, PK, Prestidge, CA, Barnes, TJ & Bremmell, KE 2016, 'Impact of PEGylation and non-ionic surfactants on the physical stability of the therapeutic protein filgrastim (G-CSF)', RSC Advances: An International Journal to Further the Chemical Sciences, vol. 6, pp. 78970-78978. Open access 3 3

Journal Articles

Year	Output
2020	Almasri, R, Joyce, P, Schultz, HB, Thomas, N, Bremmell, KE & Prestidge, CA 2020, 'Porous nanostructure, lipid composition, and degree of drug supersaturation modulate in vitro fenofibrate solubilization in silica-lipid hybrids', Pharmaceutics, vol. 12, no. 7, article no. 687, pp. 1-12. Open access 2
2020	Romana, B, Hassan, MM, Sonvico, F, Garrastazu Pereira, G, Mason, AF, Thordarson, P, Bremmell, KE, Barnes, TJ & Prestidge, CA 2020, 'A liposome-micelle-hybrid (LMH) oral delivery system for poorly water-soluble drugs: enhancing solubilisation and intestinal transport', European Journal of Pharmaceutics and Biopharmaceutics, vol. 154, pp. 338-347.
2019	Bremmell, KE & Prestidge, CA 2019, 'Enhancing oral bioavailability of poorly soluble drugs with mesoporous silica based systems: opportunities and challenges', Drug Development and Industrial Pharmacy, vol. 45, no. 3, pp. 349-358. Open access 17 18
2019	Bremmell, KE, Briskey, D, Meola, TR, Mallard, A, Prestidge, CA & Rao, A 2019, 'A self-emulsifying Omega-3 ethyl ester formulation (AquaCelle) significantly improves eicosapentaenoic and docosahexaenoic acid bioavailability in healthy adults', European Journal of Nutrition, online, pp. 1-9. 1 21
2017	Chang, PK, Prestidge, CA & Bremmell, KE 2017, 'Interfacial analysis of siRNA complexes with poly-ethylenimine (PEI) or PAMAM dendrimers in gene delivery', Colloids and Surfaces B: Biointerfaces, vol. 158, pp. 370-378. Open access 5 3
2017	Singh, G, Bremmell, K, Griesser, HJ & Kingshott, P 2017, 'Colloid-probe AFM studies of the surface functionality and adsorbed proteins on binary colloidal crystal layers', RSC Advances: An International Journal to Further the Chemical Sciences, vol. 7, no. 12, pp. 7329-7337. Open access 2 2
2017	Yasmin, R, Rao, S, Bremmell, KE & Prestidge, C 2017, 'Synergistic role of solid lipid and porous silica in improving the oral delivery of weakly basic poorly water soluble drugs', European Journal of Pharmaceutical Sciences, vol. 96, no. , pp. 508-514. 15 14
2016	Chang, PK, Prestidge, CA, Barnes, TJ & Bremmell, KE 2016, 'Impact of PEGylation and non-ionic surfactants on the physical stability of the therapeutic protein filgrastim (G-CSF)', RSC Advances: An International Journal to Further the Chemical Sciences, vol. 6, pp. 78970-78978. Open access 3 3
2016	Yasmin, R, Rao, S, Bremmell, KE & Prestidge, CA 2016, 'Porous Silica-Supported Solid Lipid Particles for Enhanced Solubilization of Poorly Soluble Drugs', AAPS Journal, vol. 18, no. 4, pp. 876-885. 6 6
2015	Diéguez, LM, Winter, MA, Pocock, KJ, Bremmell, KE & Thierry, B 2015, 'Efficient microfluidic negative enrichment of circulating tumor cells in blood using roughened PDMS', The Analyst, vol. 140, no. 10, pp. 3365-3372. Open access 31 29
2015	Ho, TT, Bremmell, KE, Krasowska, M, MacWilliams, S, Richard, CJ, Stringer, DN & Beattie, DA 2015, 'In situ ATR FTIR spectroscopic study of the formation and hydration of a fucoidan/chitosan polyelectrolyte multilayer', Langmuir: The ACS Journal of Surfaces and Colloids, vol. 31, no. 41, pp.11249-11259. 20 18 13
2015	Ho, TT, Bremmell, KE, Krasowska, M, Stringer, DN, Thierry, B & Beattie, DA 2015, 'Tuning polyelectrolyte multilayer structure by exploiting natural variation in fucoidan chemistry', Soft Matter, vol. 11, no. 11, pp. 2110-2124. 29 27 9
2015	Singh, G, Bremmell, KE, Griesser, HJ & Kingshott, P 2015, 'Colloid-probe AFM studies of the interaction forces of proteins adsorbed on colloidal crystals', Soft Matter, vol. 11, no. 16, pp. 3188-3197. 7 7
2014	Shin, Y, Cheung, WH, Ho, TT, Bremmell, KE & Beattie, DA 2014, 'Insights into hydrophobic molecule release from polyelectrolyte multilayer films using In situ and ex situ techniques', Physical Chemistry Chemical Physics, vol. 16, no. 40, pp. 22409-22417. 4 4 2
2014	Yasmin, R, Tan, A, Bremmell, KE & Prestidge, CA 2014, 'Lyophilized silica-lipid hybrid carriers for poorly water-soluble drugs : physicochemical and in vitro pharmaceutical investigations', Journal of Pharmaceutical Sciences, vol. 103, no. 9, 2950-2959. 19 17 3
2013	Bremmell, KE, Britcher, L & Griesser, HJ 2013, 'Steric and electrostatic surface forces on sulfonated PEG graft surfaces with selective albumin adsorption', Colloids and Surfaces B: Biointerfaces, vol. 106, no. 1, pp. 102-108. 5 5
2013	Bremmell, KE, Tan, A, Martin, A & Prestidge, CA 2013, 'Tableting lipid-based formulations for oral drug delivery: a case study with silica nanoparticle-lipid-mannitol hybrid microparticles', Journal of Pharmaceutical Sciences, vol. 102, no. 2, pp. 684-693. 27 28
2013	Kempson, IM, Chang, PKC, Bremmell, KE & Prestidge, CA 2013, 'Low temperature thermal dependent Filgrastim adsorption behavior detected with ToF-SIMS', Langmuir: The ACS Journal of Surfaces and Colloids, vol. 29, no. 50, pp. 15573-15578. 9 10
2011	Regini, JW, Ecroyd, H, Meehan, S, Bremmell, K, Clarke, MJ, Lammie, D, Wess, T & Carver, JA 2011, 'The interaction of unfolding α-lactalbumin and malate dehydrogenase with the molecular chaperone αB-crystallin : a light and X-ray scattering investigation', Molecular Vision, vol. 16, pp. 2446-2456. Open access 22 22
2011	Singh, G, Griesser, HJ, Bremmell, K & Kingshott, P 2011, 'Highly ordered nanometer-scale chemical and protein patterns by binary colloidal crystal lithography combined with plasma polymerization', Advanced Functional Materials, vol. 21, no. 3, pp. 540-546. 57 54
2010	Banerjee, K, Kumar, S, Bremmell, K & Griesser, H 2010, 'Molecular-level removal of proteinaceous contamination from model surfaces and biomedical device materials by air plasma treatment', Journal of Hospital Infection, vol. 76, no. 3, pp. 234-242. 8 7
2008	McFarlane, AJ, Yeap, KY, Bremmell, KE & Addai-Mensah, J 2008, 'The influence of flocculant adsorption kinetics on the dewaterability of kaolinite and smectite clay mineral dispersions', Colloids and Surfaces A: Physicochemical and Engineering Aspects, vol. 317, no. 1-3, pp. 39-48. 30 24
2008	McGuire, MJ, Addai-Mensah, J & Bremmell, KE 2008, 'Improved Dewaterability of Iron Oxide Dispersions: The Role of Polymeric Flocculant Type, pH and Shear', Asia Pacific Journal of Chemical Engineering, vol. 3, no. 1, pp. 18-23. 5 3

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Aarhus University	DENMARK
Cardiff University	UNITED KINGDOM
Marinova Pty Ltd	AUSTRALIA
RDC Clinical Pty Ltd	AUSTRALIA
University of Adelaide	AUSTRALIA
University of Cambridge	UNITED KINGDOM
University of New South Wales	AUSTRALIA
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Technology Sydney	AUSTRALIA

External engagement & recognition

Engagement/recognition	Year
Citations for Outstanding Contributions to Student Learning University of South Australia Teaching Awards	2017
Member Royal Australian Chemical Institute	2017
Member International Society of Pharmaceutical Engineering	2017

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
Solid nanostructured carrier materials for the development of novel lipid-based systems for anti-psychotic drug delivery.	Current
Strategies to improve the biopharmaceutical performance of solid-SEDDS	Current
An infrared spectroscopic study of fucoidan/chitosan polyelectrolyte multilayers for biomedical applications	Completed
Biophysics of pulmonary surfactant under thermal stress	Completed
Cationic polymer mediated siRNA complexes: relationship between intracellular delivery and physicochemical properties	Completed
Combining porous nanostructure and lipid carriers to improve oral delivery systems for poorly water soluble drugs	Completed
Formation and characterisation of fucoidan-based polyelectrolyte multilayers for applications in biomaterials	Completed
Liposome-micelle hybrid systems for oral delivery of poorly water-soluble cardiovascular drug lovastatin and anticancer drugs paclitaxel and 5-fluorouracil	Completed
The role of formulations in skin delivery	Completed

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Dr Kristen Bremmell

About me

About me

UniSA Clinical & Health Sciences

About me

Professional Associations

Experience

Qualifications

Research

Research themes

Research focus

Projects

Outputs

Highlights

Journal Articles

External engagement & recognition

Collaborations

Collaborations

External engagement & recognition

Citations for Outstanding Contributions to Student Learning

Member

Member

Teaching & student supervision

Courses and programs

Courses I teach and/or co-ordinate

Programs I'm associated with

Research degree supervision

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