Dr Leigh Donnellan

Research Associate UniSA Clinical & Health Sciences

City East Campus (P1-06)

email Leigh.Donnellan@unisa.edu.au

Research Degree Supervisor

Research

Research focus

Biochemistry and Cell Biology
Chemical Sciences
Other Biological Sciences
Biological Sciences
Clinical Sciences

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Journal Articles

Year	Output
2025	Lau, D, Donnellan, L, Harris, JC, Hayes, JE, Croser, J & Hoffmann, P 2025, 'Proteomic and lipidomic analyses reveal novel molecular insights into oat (Avena sativa L.) lipid regulation and crosstalk with starch synthesis during grain development', International Journal of Biological Macromolecules, vol. 306 PART 1, pp. 1-11. Open access
2025	Lau, WCD, Donnellan, L, Harris, JC, Seidel, J, Hayes, JE, Croser, J & Hoffmann, P 2025, 'Coupling proteomics and lipidomics for insights into regulation of oat (Avena sativa) grain lipid synthesis', Food Chemistry, vol. 478, article no. 143644, pp. 1-12.
2025	Lee, JH, Sumer-Bayraktar, Z, Mittal, P, Donnellan, L, Young, C, Rushworth, RL, Lewis, JG, Nenke, M, Rankin, W, Klingler-Hoffmann, M, Hoffmann, P, Thaysen-Andersen, M, Torpy, DJ & Meyer, EJ 2025, 'Mass spectrometric detection of neutrophil elastase cleaved corticosteroid binding globulin and its association with Asn347 site glycosylation, in septic shock patients', Clinica Chimica Acta, vol. 567, article no. 120108, pp. 1-8. Open access 1 1
2024	Lau, D, Donnellan, L, Briggs, M, Klingler-Hoffmann, M & Hoffmann, P 2024, 'MALDI Mass spectrometry imaging of metabolites in cereal grains and legumes: repurposing for industrial applications', Food Reviews International, online, pp. 1-22. Open access 1 1
2024	Lau, WC, Donnellan, L, Briggs, M, Rupasinghe, T, Harris, JC, Hayes, JE & Hoffmann, P 2024, 'Sodium doping and trapped ion mobility spectrometry improve lipid detection for novel MALDI-MSI analysis of oats', Food Chemistry, vol. 433, article no. 137275, pp. 1-10. Open access 5 5 1
2024	Seidel, JD, Condina, MR, Klingler-Hoffmann, M, Young, C, Donnellan, L, Kyngdon, C & Hoffmann, P 2024, 'Development of an optimized LC-MS workflow for host cell protein characterization to support upstream process development', Journal of Proteome Research, vol. 24, no. 1, pp. 234-243. 2
2023	Dilmetz, BA, Desire, CT, Donnellan, L, Meneses, J, Klingler-Hoffmann, M & Young, C 2023, 'Assessment of yeast physiology during industrial-scale brewing practices using the redox-sensitive dye resazurin', Yeast, vol. 40, no. 5-6, pp. 171-181. Open access 2 2 5
2023	Subramaniam, S, Joyce, P, Donnellan, L, Young, C, Wignall, A, Hoffmann, P & Prestidge, CA 2023, 'Protein adsorption determines pulmonary cell uptake of lipid-based nanoparticles', Journal of Colloid and Interface Science, vol. 641, pp. 36-47. Open access 24 22 4
2022	Donnellan, L, Simpson, BS, Dhillon, V S, Costabile, M, Fenech, M & Deo, P 2022, 'Folic acid deficiency increases sensitivity to DNA damage by glucose and methylglyoxal', Mutagenesis, vol. 37, no. 1, pp. 24-33. Open access 7 5 1
2022	Donnellan, L, Young, C, Simpson, BS, Acland, M, Dhillon, VS, Costabile, M, Hoffmann, P & Deo, P 2022, 'Proteomic analysis of methylglyoxal modifications reveals susceptibility of glycolytic enzymes to dicarbonyl stress', International Journal of Molecular Sciences, vol. 23, no. 7, article no. 3689. Open access 18 18 8
2022	Donnellan, L, Young, C, Simpson, BS, Dhillon, VS, Costabile, M, Hoffmann, P, Fenech, M & Deo, P 2022, 'Methylglyoxal impairs sister chromatid separation in lymphocytes', International Journal of Molecular Sciences, vol. 23, no. 8, article no. 4139, pp. 1-11. Open access 3 2 2
2021	Donnellan, L, Simpson, B, Dhillon, VS, Costabile, M, Fenech, M & Deo, P 2021, 'Methylglyoxal induces chromosomal instability and mitotic dysfunction in lymphocytes', Mutagenesis, vol. 36, pp. 339-348. Open access 12 11
2021	Forbes, JM, Le Bagge, S, Righi, S, Fotheringham, AK, Donnellan, L, Deo, P & O'Moore-Sullivan, T 2021, 'Advanced glycation end products as predictors of renal function in youth with type 1 diabetes', Scientific Reports, vol. 11, article no. 9422 , pp. 1-10. Open access 5 5 12
2021	Snelson, M, Min Tan, S, Clarke, RE, de Pasquale, C, Donnellan, L, Deo, P & Coughlan, MT 2021, 'Processed foods drive intestinal barrier permeability and microvascular diseases', Science Advances, vol. 7, no. 14, article no. eabe4841, pp. 1-15. Open access 110 104 1644
2020	Deo, P, Dhillon, VS, Lim, WM, Jaunay, EL, Donnellan, L, Peake, B, McCullough, C & Fenech, M 2020, 'Advanced glycation end-products accelerate telomere attrition and increase pro-inflammatory mediators in human WIL2-NS cells', Mutagenesis, vol. 35, no. 3, pp. 291-297. Open access 13 14 25
2020	Deo, P, McCullough, CL, Almond, T, Jaunay, EL, Donnellan, L, Dhillon, VS & Fenech, M 2020, 'Dietary sugars and related endogenous advanced glycation end-products increase chromosomal DNA damage in WIL2-NS cells, measured using cytokinesis-block micronucleus cytome assay', Mutagenesis, vol. 35, no. 2, pp. 1-9. 17 18 1

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Baker Heart and Diabetes Institute	AUSTRALIA
Coopers Brewery	AUSTRALIA
CSIRO Australia (Commonwealth Scientific Industrial Research organisation)	AUSTRALIA
Csl Innovation Pty Ltd	AUSTRALIA
Danaher (Canada)	CANADA
Department of Primary Industries and Regions	AUSTRALIA
Macquarie University	AUSTRALIA
Monash University	AUSTRALIA
South Australian Research and Development Institute (SARDI)	AUSTRALIA
The University of Notre Dame Australia	AUSTRALIA
University of Adelaide	AUSTRALIA
University of Otago	NEW ZEALAND
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Wollongong	AUSTRALIA

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
111153 - Mass Spectrometry assays for protein biomarker for the early detection of ovarian cancer	Current
Investigating oat (Avena sativa L.) lipid regulation through the lens of mass spectrometry	Current
Mass spectrometry and spectroscopic analytical approaches for directed monoclonal antibody formulation development	Current

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Dr Leigh Donnellan

About me

About me

UniSA Clinical & Health Sciences

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Journal Articles

External engagement & recognition

Collaborations

Collaborations

Teaching & student supervision

Courses and programs

Research degree supervision

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