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Associate Professor Lorraine Mackenzie

Associate Research Professor UniSA Clinical & Health Sciences

City West Campus (HB6-25)
tel +61 8 830 25947

email Lorraine.Mackenzie@unisa.edu.au

Research Degree Supervisor

Research

Research focus

Pharmacology and Pharmaceutical Sciences
Analytical Chemistry
Biological Sciences
Chemical Sciences
Environmental Sciences

Research

Outputs

Research outputs for the last seven years are shown below. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Journal Articles

Year	Output
2023	Mangion, SE, Mackenzie, L, Roberts, MS & Holmes, AM 2023, 'Seborrheic dermatitis: topical therapeutics and formulation design', European Journal of Pharmaceutics and Biopharmaceutics, vol. 185, pp. 148-164.
2023	Mikkonen, AT, Martin, J, Upton, RN, Barker, AO, Brumley, CM, Taylor, MP, Mackenzie, L & Roberts, MS 2023, 'Spatio-temporal trends in livestock exposure to per- and polyfluoroalkyl substances (PFAS) inform risk assessment and management measures', Environmental Research, vol. 225, article no. 115518, pp. 1-14. Open access
2022	Alinaghi, A, Zhang, Q, Williams, DB, Mackenzie, L & Roberts, MS 2022, 'Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning', International Journal of Pharmaceutics, vol. 630, article no. 122424, pp. 1-10. 1 1
2022	Qiang, S, Mohamed, F, Mackenzie, L & Roberts, MS 2022, 'Rapid determination of polyethoxylated tallow amine surfactants in human plasma by LC-MSMS', Talanta, vol. 254, article no. 124115, pp. 1-12.
2022	Rambabu, L, Mohamed, F, Dhanarisi, J, Gawarammana, I, Raubenheimer, J, Mackenzie, L, Roberts, M, Buckley, N & Eddleston, M 2022, 'Acute phenthoate self-poisoning: a prospective case series', Clinical Toxicology, vol. 60, no. 2, pp. 214-220. 1 3 3
2021	Al-Qurain, AA, Gebremichael, LG, Khan, MS, Williams, DB, Mackenzie, L, Phillips, C, Russell, P, Roberts, MS & Wiese, MD 2021, 'Opioid prescribing and risk of drug-opioid interactions in older discharged patients with polypharmacy in Australia', International Journal of Clinical Pharmacy, vol. 43, no. 2, pp. 365-374. 2 4 4
2021	Al-Qurain, AA, Upton, R, Williams, DB, Mackenzie, L, Phillips, C, Russell, PT, Tadros, R, Roberts, MS & Wiese, MD 2021, 'Population pharmacokinetic model of subcutaneous fentanyl in older acute care patients', European Journal of Clinical Pharmacology, vol. 77, no. 9, pp. 1357-1368. 1 1
2021	Al-Qurain, AA, Williams, DB, Mackenzie, L, Roberts, MS & Wiese, MD 2021, 'Simultaneous LC-MS/MS quantification of oxycodone, tramadol and fentanyl and their metabolites (noroxycodone, oxymorphone, O- desmethyltramadol, N- desmethyltramadol, and norfentanyl) in human plasma and whole blood collected via venepuncture and volumetric absorptive micro sampling', Journal of Pharmaceutical and Biomedical Analysis, vol. 203, article no. 114171, pp. 1-8. 4 3 2
2021	Gebremichael, LG, Suppiah, V, Wiese, MD, Mackenzie, L, Phillips, C, Williams, DB & Roberts, MS 2021, 'Efficacy and safety of statins in ethnic differences: a lesson for application in Indigenous Australian patient care', Pharmacogenomics, vol. 22, no. 9, pp. 553-571. 1
2020	Al-Qurain, AA, Gebremichael, LG, Khan, MS, Williams, DB, Mackenzie, L, Phillips, C, Russell, P, Roberts, MS & Wiese, MD 2020, 'Prevalence and factors associated with analgesic prescribing in poly-medicated elderly patients', Drugs and Aging, vol. 37, no. 4, pp. 291-300. 9 9 2
2020	Holmes, AM, Mackenzie, L & Roberts, MS 2020, 'Disposition and measured toxicity of zinc oxide nanoparticles and zinc ions against keratinocytes in cell culture and viable human epidermis', Nanotoxicology, vol. 14, no. 2, pp. 263-274. 25 21 1

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Royal Adelaide Hospital	AUSTRALIA
University of Edinburgh	UNITED KINGDOM
University of Peradeniya	SRI LANKA
University of South Australia	AUSTRALIA
University of Sydney	AUSTRALIA

Teaching & student supervision

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
Comparison of skin morphological and physiological profiles in health and disease	Current
Exploring the hair follicles as targets to improve the effectiveness of antidandruff therapies	Current
Investigation of the pharmacokinetics pharmacodynamics of per- and polyfluoroalkyl substances (PFAS) in food production animals and development of models to predict biological loading and potential	Current
Liquid chromatography-tandem mass spectrometry based bioanalysis for assessment of glyphosate-surfactant product exposure: clinical toxicology and pharmacokinetics	Current
Assessing patterns and appropriateness of prescription of medications in elderly patients admitted to South Australian Hospitals	Completed
Getting through the skin¿s formidable barrier ¿ understanding the role of solute structure, skin morphology and formulation in skin delivery	Completed
Liquid chromatography-tandem mass spectrometry-based bioanalysis to assess toxicological and therapeutic aspects in human disease conditions	Completed
Opioid prescribing in older patients; pharmacoepidemiology and pharmacokinetics	Completed
Skin deep ¿ understanding the transport within the skin and nail for formulation design	Completed

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