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Dr Marnie Winter

  • Research Fellow Future Industries Institute
  • Mawson Lakes Campus (MM2-01)
  • tel +61 8 830 23415
  • email Marnie.Winter@unisa.edu.au
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About me

About me

Dr Marnie Winter

Dr Marnie Winter is currently leading an ambitious research theme at the Future Industries Institute, focussed on developing bioengineering technologies to improve prenatal care and address common pregnancy complications such as preeclampsia which have severe consequences for both mother and baby. Specifically, Marnie and her team are developing novel approaches to screen, manage and treat pregnancy complications. Marnie’s work is also focused on developing in vitro models that can improve the molecular understanding of placental dysfunction (such as preeclampsia) with the aim to help us understand molecular origins of disease and accelerate the drug development pipeline. As an emerging leader, in 2019, Marnie was awarded the... Read more

Future Industries Institute

The Institute partners with today’s industries, to create the industries of tomorrow.

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About me

Dr Marnie Winter is currently leading an ambitious research theme at the Future Industries Institute, focussed on developing bioengineering technologies to improve prenatal care and address common pregnancy complications such as preeclampsia which have severe consequences for both mother and baby. Specifically, Marnie and her team are developing novel approaches to screen, manage and treat pregnancy complications. Marnie’s work is also focused on developing in vitro models that can improve the molecular understanding of placental dysfunction (such as preeclampsia) with the aim to help us understand molecular origins of disease and accelerate the drug development pipeline. As an emerging leader, in 2019, Marnie was awarded the prestigious international Thrasher Early Career Award Grant and also a Young Tall Poppy of Science (South Australia) Award.  Since 2017, Marnie has also co-led a signature project for the ARC Centre of Excellence in Convergent BioNano Science and Technology “New tools for quantifying and manipulating rare entities directly into biological fluids”. 

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Professional Associations

Healthy Development Adelaide

Australasian Cytometry Society

AusBiotech

The Australian Nanotechnology Network

Australian Society of Medical Research 

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In the media

Date Title
06/08/2018

The Advertiser - SOAK UP SOME SCIENCE, https://www.adelaidenow.com.au/technology/science/explore-nanotechnology-with-expert-guides-during-national-science-week/news-story/796993e4e88fe45288883e244a5234a9

20/07/2018

7 News - Tiny chip shining a light inside the womb, https://www.facebook.com/7newssydney/videos/2224630870894367/

23/06/2018

2SER - Breakthrough early pregnancy blood test for foetal abnormalities, https://2ser.com/breakthrough-early-pregnancy-blood-test-for-foetal-abnormalities/

14/06/2018

The Lead - Tiny device takes big step in non-invasive fetal blood test technology, http://theleadsouthaustralia.com.au/industries/health/tiny-device-takes-big-step-non-invasive-fetal-blood-test-technology/

14/06/2018

Blood test on mother for foetus, http://online.isentialink.com/adelaidenow.com.au/2018/06/14/b1711354-8877-41bd-9653-a3dc1435f83c.html

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Experience

Qualifications

  • Doctor of Philosophy University of South Australia

  • Bachelor of Laboratory Medicine with Honours University of South Australia

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  • Professional associations
  • In the media
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Research

Research themes

  • Cancer
  • Healthy futures

Research focus

  • Analytical Chemistry
  • Chemical Engineering
  • Other Chemical Sciences
  • Biochemistry and Cell Biology
  • Biological Sciences

Highlights

Dr Marnie Winter is biomedical researcher at the newly established Future Industries Institute in the Biomaterials Engineering and Nanomedicine research strand alongside Prof Benjamin Thierry. As an emerging leader in her field, Marnie aspires to transform prenatal care through the development of novel technologies. A significant focus of this work has been the development of a non-invasive prenatal test to improve clinical diagnosis of pregnancy complications and genetic abnormalities. Marnie and her team are also working on developing in vitro models that can improve the molecular understanding of placental dysfunction (including preeclampsia and stillbirth) and accelerate drug development pipelines for such conditions. This work has... Read more

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Research

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Projects

Excludes commercial-in-confidence projects.

  • Circulating Fetal Cells: A new paradigm for the early detection of preeclampsia, Thrasher Research Fund, 01/07/2019 - 30/06/2020

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Research

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Outputs

Research since 2008 is shown below. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Highlights

Year Output
2019

Rezaei, M, Winter, M, Zander-Fox, D, Whitehead, C, Liebelt, J, Warkiani, ME, Hardy, T & Thierry, B 2019, 'A reappraisal of circulating fetal cell noninvasive prenatal testing', Trends in Biotechnology, vol. 37, no. 6, pp. 632-644.

Open access 2 2 2
2019

Winter, M, Cai, Z, Winkler, K, Georgiou, K, Inglis, D, Lavranos, T, Rezaei, M, Warkiani, M & Thierry, B 2019, 'Circulating tumour cell RNA characterisation from colorectal cancer patient blood after inertial microfluidic enrichment', MethodsX, vol. 6, pp. 1512-1520.

Open access 1 1 3
2018

Winter, M, Hardy, T, Rezaei, M, Nguyen, V, Zander-Fox, D, Warkiani, ME & Thierry, B 2018, 'Isolation of circulating fetal trophoblasts using inertial microfluidics for noninvasive prenatal testing', Advanced Materials Technologies, vol. 3, no. 7, article no. 1800066 , pp. 1-10.

Open access 7 7 63
2016

Duy Tran, Winter, M, Wolfrum, B, Stockmann, R, Yang, C-T, Pourhassan-Moghaddam, M, Offenhaüsser, A & Thierry, B 2016, 'Toward intraoperative detection of disseminated tumor cells in lymph nodes with silicon nanowire field effect transistors', ACS Nano, vol. 10, no. 2, pp. 2357-2364.

Open access 22 22 53
2015

Diéguez, LM, Winter, MA, Pocock, KJ, Bremmell, KE & Thierry, B 2015, 'Efficient microfluidic negative enrichment of circulating tumor cells in blood using roughened PDMS', The Analyst, vol. 140, no. 10, pp. 3365-3372.

26 27

Journal Articles

Year Output
2019

Rezaei, M, Winter, M, Zander-Fox, D, Whitehead, C, Liebelt, J, Warkiani, ME, Hardy, T & Thierry, B 2019, 'A reappraisal of circulating fetal cell noninvasive prenatal testing', Trends in Biotechnology, vol. 37, no. 6, pp. 632-644.

Open access 2 2 2
2019

Tran, DP, Winter, M, Yang, C-T, Stockmann, R, Offenhausser, A & Thierry, B 2019, 'Silicon nanowires field effect transistors: a comparative sensing performance between electrical impedance and potentiometric measurement paradigms', Analytical Chemistry, vol. 91, no. 19, pp. 12568-12573.

2019

Winter, M, Cai, Z, Winkler, K, Georgiou, K, Inglis, D, Lavranos, T, Rezaei, M, Warkiani, M & Thierry, B 2019, 'Circulating tumour cell RNA characterisation from colorectal cancer patient blood after inertial microfluidic enrichment', MethodsX, vol. 6, pp. 1512-1520.

Open access 1 1 3
2018

Diéguez, L, Winter, M, Molan, S, Monis, P, King, B & Thierry, B 2018, 'Disposable microfluidic micromixers for effective capture of Cryptosporidium parvum oocysts from water samples', Journal of Biological Engineering, vol. 12, no. 1, article no. 4, pp. 1-8.

Open access 1 1
2018

Winter, M, Hardy, T, Rezaei, M, Nguyen, V, Zander-Fox, D, Warkiani, ME & Thierry, B 2018, 'Isolation of circulating fetal trophoblasts using inertial microfluidics for noninvasive prenatal testing', Advanced Materials Technologies, vol. 3, no. 7, article no. 1800066 , pp. 1-10.

Open access 7 7 63
2016

Duy Tran, Winter, M, Wolfrum, B, Stockmann, R, Yang, C-T, Pourhassan-Moghaddam, M, Offenhaüsser, A & Thierry, B 2016, 'Toward intraoperative detection of disseminated tumor cells in lymph nodes with silicon nanowire field effect transistors', ACS Nano, vol. 10, no. 2, pp. 2357-2364.

Open access 22 22 53
2015

Diéguez, LM, Winter, MA, Pocock, KJ, Bremmell, KE & Thierry, B 2015, 'Efficient microfluidic negative enrichment of circulating tumor cells in blood using roughened PDMS', The Analyst, vol. 140, no. 10, pp. 3365-3372.

26 27
2015

Hardingham, JE, Grover, P, Winter, M, Hewett, PJ, Price, TJ & Thierry, B 2015, 'Detection and clinical significance of circulating tumor cells in colorectal cancer: 20 years of progress', Molecular Medicine, vol. 21, pp. S21-S25.

Open access 59 54
2015

Winter, M, Gibson, R, Ruszkiewicz, A, Thompson, SK & Thierry, B 2015, 'Beyond conventional pathology: towards preoperative and intraoperative lymph node staging', International Journal of Cancer, vol. 136, no. 4, pp. 743-751.

Open access 6 5 3
2014

Liu, T, Winter, M & Thierry, B 2014, 'Quasi-spherical microwells on superhydrophobic substrates for long term culture of multicellular spheroids and high throughput assays', Biomaterials, vol. 35, no. 23, pp. 6060-6068.

19 21 6
2014

Wan, Y, Winter, M, Delalat, B, Hardingham, JE, Grover, PK, Wrin, J, Voelcker, N, Price, TJ & Thierry, B 2014, 'Nanostructured polystyrene well plates allow unbiased high-throughput characterization of circulating tumor cells', ACS Applied Materials and Interfaces, vol. 6, no. 23, pp. 20828-20836.

22 21
2012

Keating, D, Winter, M, Hemsley, K, Mackenzie, K, Teo, E, Hopwood, J, Brooks, D & Parkinson-Lawrence, E 2012, 'Exocytosis is impaired in mucopolysaccharidosis IIIA mouse chromaffin cells', Neuroscience, vol. 227, no. 27, pp. 110-118.

10 10

Other outputs

Marnie Winter, Benjamin Thierry, PCT/AU2019/000013; PRE-NATAL CELL ISOLATION

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Research

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Current research & highlights

Dr Marnie Winter is biomedical researcher at the newly established Future Industries Institute in the Biomaterials Engineering and Nanomedicine research strand alongside Prof Benjamin Thierry. As an emerging leader in her field, Marnie aspires to transform prenatal care through the development of novel technologies. A significant focus of this work has been the development of a non-invasive prenatal test to improve clinical diagnosis of pregnancy complications and genetic abnormalities. Marnie and her team are also working on developing in vitro models that can improve the molecular understanding of placental dysfunction (including preeclampsia and stillbirth) and accelerate drug development pipelines for such conditions. This work has been supported by a Thrasher Early Career Award, the ARC Centre of Excellence in Convergent Bionano Science and Technology and UniSA.

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External engagement & recognition

Collaborations

Highlights

In 2019, Marnie was a South Australian Young Tall Poppy of Science winner, recognising her scientific and also outreach achievements.

Since 2017, Marnie has been the UniSA Post-Doctoral representative of the CBNS Education Committee. As part of this Marnie is involved and co-ordinates a number of educational and outreach activities for members of the CBNS and also the general public. In 2017, she organised presentations from 8 researchers to over 160 year 10 students. In 2018, she organised the successful 'Super Drugs and Mini-Guts' event for National Science Week which brought 50 Year 11 students with 25 UniSA researchers (https://www.cbns.org.au/events/national-science-week-unisa/). The 2019 full day event 'To BioNano and Beyond' was even more successful brining 50 year 10/11 students from 6 South Australian Schools together with 25 UniSA researchers for interactive activities to promote STEM.

Marnie is regularly invited to review manuscripts for bioengineering journals and have been invited to chair and speak at various events including conferences and community outreach.

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External engagement & recognition

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Collaborations

Organisation Country
Bionomics Ltd. AUSTRALIA
Flinders University AUSTRALIA
Forschungszentrum Jülich GERMANY
Monash IVF Group AUSTRALIA
Peter Grunberg Institute (PGI) GERMANY
Queen Elizabeth Hospital AUSTRALIA
Repromed AUSTRALIA
SA Pathology AUSTRALIA
SA Water Corporation AUSTRALIA
Sechenov First Moscow State Medical University RUSSIAN FEDERATION
Southern Medical University CHINA
Tabriz University of Medical Sciences IRAN
University of Adelaide AUSTRALIA
University of South Australia AUSTRALIA
University of Technology Sydney AUSTRALIA
University of Toronto CANADA
Women's and Children's Hospital AUSTRALIA
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External engagement & recognition

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External engagement & recognition

Engagement/recognition Year

Committee Member

Convergent Bio-Nano Science and Technology

2019

Founding member and interim co-chair

BLiSS*Adelaide (Adelaide ECR conference)

2019

Invited Lecture to clinical industry partner for staff education

Repromed

2019

Newsletter article

Franklin Women

2019

Semi-Finalist, First National Real Estate Innovation Award

Seven News Young Achiever Awards South Australia

2019

Semi-Finalist, The University of Adelaide STEM Award

Seven News Young Achiever Awards South Australia

2019

Young Tall Poppy Science Award

Australian Institute of Policy and Science

2019

Best Oral Presentation Award

Frontiers in Bio-Nano Science a Convergent Bio-Nano Science and Technology Early to Mid Career Researcher Event

2018

Committee Member

Convergent Bio-Nano Science and Technology

2018

Community grant ($1,800)

National Science Week South Australia Branch

2018

Finalist, Winnovation Award (Technology)

Women in Innovation SA

2018

Founding member and interim co-chair

BLiSS*Adelaide (Adelaide ECR conference)

2018

Invited lecture at the Australasian Association of Clinical Biochemists and Australian Institute of Medical Scientists Combined Scientific meeting (Sydney 2018)

Australian Institute of Medical Scientists

2018

Magazine article

The Pathologist - leading professional magazine

2018

Committee Member

Convergent Bio-Nano Science and Technology

2017

Organiser of national science week events (and other public outreach)

ARC CoE Convergent Bio-Nano Science and Technology

2017

Best oral presentation (PhD)

Australian Society for Medical Research SA Scientific Meeting

2016

Best Poster Presentation Award

EMBL Australia Postgraduate Symposium

2016

Fresh Science Finalist (South Australia)

Fresh Science

2015

Other

Marnie is a founding member and current co-chair (acting) for a new symposium (Adelaide*BLiSS) that was conceived to break down silos and promote EMCR inter-disciplinary/university collaborations.

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Courses and programs

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Research degree supervision

Supervisions from 2010 shown

Thesis title Student status
Development of a lab-on-chip technology for single cell whole genome amplification Current
Understanding and targeting preeclampsia molecular mechanisms for improved pregnancy outcomes. Current
Isolation and analysis of circulating fetal cells: towards improved non-invasive prenatal diagnosis of genetic disorders Completed
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Gallery

Dr Marnie Winter
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