Professor Michael Fenech is recognised internationally for his research in nutritional genomics and genetic toxicology and for developing the cytokinesis-block micronucleus (CBMN) assay which is now a standard method used internationally to measure DNA damage in human and mammalian cells. The lymphocyte CBMN assay has been endorsed by the International Atomic Energy Agency and the OECD for in vivo radiation bio-dosimetry and in vitro testing of chemical genotoxicity, respectively. From 1990 to 2018 he worked as a principal research scientist in Australia at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) in the field of human nutrition. In 1999-2009 his laboratory further developed the lymphocyte CBMN assay into a... Read more
About me
Professor Michael Fenech is recognised internationally for his research in nutritional genomics and genetic toxicology and for developing the cytokinesis-block micronucleus (CBMN) assay which is now a standard method used internationally to measure DNA damage in human and mammalian cells. The lymphocyte CBMN assay has been endorsed by the International Atomic Energy Agency and the OECD for in vivo radiation bio-dosimetry and in vitro testing of chemical genotoxicity, respectively. From 1990 to 2018 he worked as a principal research scientist in Australia at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) in the field of human nutrition. In 1999-2009 his laboratory further developed the lymphocyte CBMN assay into a 'cytome' assay consisting of six complementary biomarkers of DNA damage and cytotoxicity and, in collaboration with other laboratories, he coordinated the establishment of a similar method for buccal epithelial cells. Both methods are published in Nature Protocols. His key goal is to determine the nutritional, lifestyle and environmental requirements for DNA damage prevention. His research is focused on (i) the impact of nutrition on chromosomal and telomere integrity and (ii) personalised nutrition for healthy aging. He co-founded the HUMN project on micronuclei in human populations in 1997 and the Asia Pacific Nutrigenomics Nutrigenetics Organisation (www.apnno.com) in 2014. Since 2010 he has been an invited speaker at 57 international conferences (10 plenary lectures). His H-index is 88 based on 36,861 total career citations according to Google Scholar.
Research
Research since 2008 is shown below. To see earlier years visit ORCID
Open access indicates that an output is open access.
Year | Output |
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2020 |
|
2020 |
3
3
1
|
2020 |
Open access
2
2
|
2020 |
|
2020 |
Open access
|
2020 |
1
|
2020 |
1
|
2020 |
Open access
3
3
|
2019 |
Open access
6
11
|
2019 |
7
7
7
|
2019 |
Open access
12
21
5
|
2019 |
Open access
2
|
2018 |
Open access
1
1
|
2016 |
Open access
11
8
|
2012 |
Open access
48
42
23
|
2011 |
196
178
|
2011 |
Open access
154
131
40
|
2010 |
Open access
17
16
|
2010 |
56
51
|
2008 |
Open access
19
15
|
External engagement & recognition
Organisation | Country |
---|---|
Aarhus University | DENMARK |
Cell Environment | FRANCE |
CSIRO Australia (Commonwealth Scientific Industrial Research Organisation) | AUSTRALIA |
Flinders University | AUSTRALIA |
Fudan University | CHINA |
Gazi University | TURKEY |
Groupe Hospitalier de la Région de Mulhouse et Sud Alsace Mulhouse (GHRMSA) | FRANCE |
IRCCS San Raffaele Pisana | ITALY |
Jilin University | CHINA |
Johns Hopkins University | UNITED STATES |
Medical University of Vienna | AUSTRIA |
Medical University Vienna | AUSTRIA |
National Cancer Institute | UNITED STATES |
National Cancer Research Institute | UNITED KINGDOM |
National University of Singapore | SINGAPORE |
Radboud University Nijmegen | NETHERLANDS |
Royal Adelaide Hospital | AUSTRALIA |
San Martino Hospital | ITALY |
San Raffaele University | ITALY |
South Australian Health and Medical Research Institute (SAHMRI) | AUSTRALIA |
Université Paris-Saclay | FRANCE |
University in Brussels | BELGIUM |
University of Adelaide | AUSTRALIA |
University of Auckland | NEW ZEALAND |
University of California, Berkeley | UNITED STATES |
University of South Australia | AUSTRALIA |
University of Toronto | CANADA |
University of Upper Alsace (UHA) | FRANCE |
Women's and Children's Health Network | AUSTRALIA |
Yunnan Normal University | CHINA |
Teaching & student supervision
Supervisions from 2010 shown
Thesis title | Student status |
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Interaction of advanced glycation end products with receptors and their effect on insulin resistance | Current |
Investigation of extracts of Australian native food and medicinal plants against advanced glycation endproduct-induced cellular damage | Current |
A nutrigenomic study of folate/methionine status and oxidative stress in autistic disorder | Completed |