Professor Michael Roberts

Emeritus Professor UniSA Clinical & Health Sciences

City West Campus (HB6-25)
tel +61 8 830 22815

email Michael.Roberts@unisa.edu.au

Research Degree Supervisor

About me

UniSA Clinical & Health Sciences

UniSA Clinical & Health Sciences is addressing society’s most critical and emerging health needs through quality teaching, learning and research excellence.

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About me

Mike Roberts has a particular interest in therapeutics and pharmaceutical sciences with current studies in critical care medicine, hepatology, quality use of medicines in the community, nanotoxicology, topical delivery, renal impairment after pesticide poisoning, nicotine addiction, pharmacokinetics, drug devlopment and cosmetology. He is probably best known internationally for his work on the absorption of chemicals, cosmetics and drugs through the skin. He has been a full professor for 25 years being initially Professor and Head of Pharmacy at the University of Otago, New Zealand and now as a Senior Principal Research Fellow of the Australian National Health and Medical Research Council. He is jointly appointed as the Chair In Therapeutics and Pharmaceutical Science in the University of South Australia and as the Professor of Clinical Pharmacology and Therapeutics at the University of Queensland. He is also visiting Professeur at the University of Lyon, France and is Director of the Therapeutics Research Centre ( 30 staff and students), based jointly at the Queen Elizabeth Hospital in Adelaide and at and Princess Alexandria Hospital in Brisbane. Mike also co-chairs The Therapeutics and Pharmaceutical Science Consortium in UniSA’s Sansom Institute and leads the inaugural SA government-UniSA pharmacy practitioner program. His research journey began with an undergraduate project studying solute chemical structure-plastic container sorption relationships in the Reid Building, where his office is now located at UniSA. The resulting studies on drugs uptake by plastic containers and infusion systems are widely referred to in journal reviews, pharmacy references and text books and resulted in forms of their recommended polyolefin infusion systems being widely marketed. His PhD was on structure penetration and toxicity relationships for phenolic compounds in human skin. This work is now included as core data in pharmaceutical and toxicological data bases (eg US Environmental Protection Agency). He has served/serves on reference committees for WHO, Europe, Health Canada and Australia and presented to regulatory forums in the US. Mike’s RCTs in the community led, in part, to the Australian government national implementation of medication management for nursing homes and hostels (also now an accreditation requirement), and home medicine reviews by accredited pharmacists. Most recently, he has facilitated the use of imaging and microdialysis techniques to study pharmacokinetics in man in vitro and in vivo, including in critical care and cancer medicine.

Research

Research focus

Pharmacology and Pharmaceutical Sciences
Clinical Sciences
Public Health and Health Services
Chemical Sciences
Medical Biotechnology

Highlights

I have undertaken and published peer reviewed research across a range of disciplines including: rational drug design, drug delivery (especially skin and oral), clinical pharmacokinetics, the pharmacist’s role in quality use of medicines and translation of research into practice/commercial outcomes. An overarching theme has been a mechanistic understanding of solute structure – delivery system physiological pharmacokinetic relationships and their clinical application.My predominant focus, has, however, been the skin and its interaction with chemicals, formulations and associated technologies. In recent years, I have had a keen interest in how to measure these interactions better and have embraced the use of non-invasive, high resolution,...

Research

Projects

Excludes commercial-in-confidence projects.

Addressing potentially life-threatening ketoacidosis associated with key antidiabetic medicines, The Hospital Research Foundation, 01/01/2021 - 31/12/2023
Investigation of the pharmacokinetics and pharmacodynamics of per-and polyfluoroalkyl substances (PFAS), Environment Protection Authority of Victoria, 01/01/2020 - 31/03/2023
Priming cancer for radiotherapy, Tour de Cure Ltd, 01/01/2020 - 30/09/2022
Improving therapeutic and toxicological outcomes, NHMRC - Research Fellowship, 01/01/2016 - 31/12/2021
Characterization of critical quality attributes for semisolid topical drug products, US Food and Drug Administration, 09/10/2014 - 31/12/2020
Properties of nanomaterials determine their disposal by liver cells, ARC - Discovery Projects, 01/01/2017 - 30/12/2020
Physiological based biopharmaceuticals and pharmacokinetics of drug for dermal absorption in humans, US Food and Drug Administration, 10/09/2014 - 28/02/2019
Minimising treatment related toxicities in vulnerable patients using a pharmacokinetic based approach, NHMRC - Program Grant, 01/01/2018 - 31/12/2018
An integrated research program in human toxicology to ensure rapid translation of results into practice and regulation , NHMRC - Program Grant, 01/01/2014 - 31/12/2018
Optimizing sample preparation for analysis for Toxicokinetic and Toxicodynamic assessment, storage and tracking following Poison Exposures, NHMRC - Program Grant, 01/11/2016 - 31/12/2018
Closing the data gap: High throughput screening of nanoparticle toxicity, ARC - Discovery Projects, 01/01/2015 - 01/10/2018
Nanotechnology based delivery and response systems CPP28, Collaboration Pathways Program (DSD), 01/05/2014 - 30/06/2017
Refining regulatory toxicology through the integration of human clinical toxicology and mechanistic findings, Central Adelaide Local Health Network Incorporated, 04/07/2016 - 28/02/2017
Clinical toxicology of various consumer products and poisons after dermal exposure, Central Adelaide Local Health Network Incorporated, 04/07/2016 - 21/02/2017

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID, ResearcherID or Scopus

Open access indicates that an output is open access.

Books

Year	Output
2021	Berner, B, Gordi, T, Benson, HA & Roberts, MS 2021, Drug delivery approaches: Perspectives from pharmacokinetics and pharmacodynamics, Wiley, US. 1
2021	Kostewicz, ES, Vertzoni, M, Benson, HA & Roberts, MS 2021, Oral drug delivery for modified release formulations, John Wiley & Sons, Inc, US.
2015	Flynn, GL & Roberts, MS 2015, Physical and biophysical foundations of pharmacy practice: issues in drug delivery, Michigan Publishing in partnership with the University of Michigan College of Pharmacy, US. Open access

Chapters

Year	Output
2022	Benson, HA & Roberts, MS 2022, 'Challenges and innovations of controlled drug delivery', in HAE Benson et al. (eds), Fundamentals of Drug Delivery, Wiley, US, ch. 1, pp. 3-14. 3
2022	Wang, H, Yang, H, Ruan, Q, Roberts, MS & Liang, X 2022, 'Theranostic nanoparticles for imaging and targeted drug delivery to the liver', in HAE Benson et al. (eds), Fundamentals of Drug Delivery, Wiley, US, ch. 12, pp. 311-328.
2018	Holmes, A, Thorling, C, Liu, X, Liang, X, Wang, H, Breunig, HG, König, K, Studier, H & Roberts, MS 2018, 'Revealing interaction of dyes and nanomaterials by multiphoton imaging', in K Karsten (ed.), Multiphoton microscopy and fluorescence lifetime imaging: applications in biology and medicine, Walter de Gruyter GmbH, Germany, ch. 18, pp. 345-368. Open access 3
2017	Grice, JE, Moghimi, HR, Ryan, E, Zhang, Q, Haridass, I, Mohammed, Y & Roberts, MS 2017, 'Non-formulation parameters that affect penetrant-skin-vehicle interactions and percutaneous absorption', Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin: Methodology and General Considerations, Springer, Germany, ch. 4, pp. 45-75. 15
2017	Leite-Silva, V, Grice, J, Mohammed, Y, Moghimi, H & Roberts, M 2017, 'The influence of emollients on dermal and transdermal drug delivery', Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin: Methodology and General Considerations, Springer, Germany, ch. 5, pp. 77-93. 10
2017	Liang, X, Wang, H, Liu, X, Grice, J, Xu, ZP & Roberts, M 2017, 'Related topic: safety evaluation of nanomaterials', in K Sugibayashi (ed.), Skin permeation and disposition of therapeutic and cosmeceutical compounds, Springer, Japan, ch. 28, pp. 313-322. 1
2017	Liu, X, Wang, H, Liang, X & Roberts, M 2017, 'Hepatic metabolism in liver health and disease', Liver pathophysiology: therapies and antioxidants, Academic Press, UK, ch. 30, pp. 391-400. 40
2017	Mohammed, Y, Moghimi, H, Yousef, SA, Chandrasekaran, NC, Bibi, CR, Sukumar, SC, Grice, J, Sakran, W & Roberts, M 2017, 'Efficacy, safety and targets in topical and transdermal active and excipient delivery', Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin: Methodology and General Considerations, Springer, Germany, ch. 23, pp. 369-391. 9
2017	Pastore, MN & Roberts, MS 2017, 'Selection of topically applied chemical candidates: Transdermal drug delivery systems', in K Sugibayashi (ed.), Skin permeation and disposition of therapeutic and cosmeceutical compounds, Springer Japan KK, Japan, ch. 21, pp. 251-262. 4
2016	Benson, H, Mohammed, Y, Grice, J & Roberts, M 2016, 'Formulation effects on topical nanoparticle penetration', in MR Hamblin, P Avci & TW Prow (eds), Nanoscience in dermatology, Academic Press, UK, ch. 9, pp. 115-126. 11
2016	Ryan, E, Grice, JE & Roberts, MS 2016, 'Nanotechnology for topical and transdermal drug delivery and targeting', in JL Arias (ed.), Nanotechnology and drug delivery, volume two: nano-engineering strategies and nanomedicines against severe diseases, CRC Press, US, ch. 4, pp. 75-101.
2016	Thorling, CA, Holmes, A, Studier, H, Liu, D, Liang, X & Roberts, MS 2016, 'Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver', in SG Stanciu (ed.), Micro and nanotechnologies for biotechnology, InTech, Croatia, ch. 5, pp. 107-123. Open access
2015	Kuswahyuning, R, Grice, JE, Moghimi, HR & Roberts, MS 2015, 'Formulation effects in percutaneous absorption', in N Dragicevic & HI Maibach (eds), Percutaneous penetration enhancers chemical methods in penetration enhancement : drug manipulation strategies and vehicle effects, Springer, Berlin, ch. 9, pp. 109-134. 6
2015	Sanchez, WY, Pastore, M, Haridass, IN, König, K, Becker, W & Roberts, MS 2015, 'Fluorescence lifetime imaging of the skin', in W Becker (ed.), Advanced time-correlated single photon counting applications, Springer, Switzerland, ch. 15, pp. 457-508. 8
2014	Anissimov, YG & Roberts, MS 2014, 'Mathematical models for topical and transdermal drug products', in Shah, Vinod P, Maibach, Howard I & Jenner, J (eds), Topical drug bioavailability, bioequivalence, and penetration, 2ed, Springer, United States, ch.15, pp. 249-298.
2014	Sanchez, WY, Song, Z, Becker, W, Koenig, K & Roberts, MS 2014, 'Fluorescence lifetime imaging for diagnostic and therapeutic intravital microscopy', in R Weigert (ed.), Advances in intravital microscopy, Springer, US, ch. 16, pp. 371-418. 2
2011	Geusens, B, Mollet, I, Anderson, CD, Terras, S, Roberts, MS & Lambert, J 2011, 'Changes in skin immunity with age and disease', in N Dayan & PW Wertz (eds), Innate Immune System of Skin and Oral Mucosa: Properties and Impact in Pharmaceutics, Cosmetics, and Personal Care Products, Wiley-Blackwell, US, ch. 11, pp. 217-258. 1
2011	Grice, JE, Prow, TW, Kendall, MA & Roberts, MS 2011, 'Electrical and physical methods of skin penetration enhancement', in HAE Benson & AC Watkinson (eds), Topical and transdermal drug delivery: principles and practice, Wiley, US, ch. 3, pp. 43-66. 12
2011	Wu, Y-T, Anissimov, YG & Roberts, MS 2011, 'Introduction to dermatokinetics', in SN Murthy (ed.), Dermatokinetics of therapeutic agents, CRC Press, US, ch. 1, pp. 1-24.
2008	Dancik, Y, Roberts, MS & Jepps, O 2008, 'Physiologically based pharmacokinetics and pharmacodynamics of skin', in MS Roberts & KA Walters, Dermal absorption and toxicity assessment, Second Edition, 2, Informa Healthcare, New York, pp. 179-207.
2008	Gierden, A, Roberts, MS, Riviere, J & Monteriro-Riviere, N 2008, 'Solvent and vehicle effects on the skin', in MA Robert, KA Walters, Dermal absorption and toxicity assessment, Second Edition, 2, Informa Healthcare, USA, pp. 433-447.
2008	Roberts, MS & Walters, K 2008, 'Human skin morphology and dermal absorption', in Robert MS Walkers K.A, Dermal absorption and toxicity assessment, Second Edition, 2, Informa Healthcare, New York, pp. 1-15.
2008	Roberts, MS, Jepps, O & Dancik, Y 2008, 'Beyond stratum corneum', in MS Roberts & KA Walters, Dermal Absorption and Toxicity Assessment, 2, Informa Healthcare, New York, pp. 209-250.

Journal Articles

Year	Output
2025	Ionmhain, UN, Chiew, AL, Tierney, M, Al Ahmad, J, Pidcock, S, Whan, FT, Mackenzie, L, Roberts, MS & Roberts, DM 2025, 'Loperamide-induced severe cardiotoxicity: a toxicokinetic and toxicodynamic analysis derived from a case series and the published literature', Clinical Toxicology, online, pp. 1-10. Open access
2025	Roberts, MS, Zhang, Q, Mackenzie, L & Medley, GA 2025, 'Quantitative structure permeability relationships for phenolic compounds applied to human epidermal membranes in various solvents', European Journal of Pharmaceutical Sciences, vol. 204, article no. 106914, pp. 1-13. Open access
2025	Shihana, F, Wijerathna, TM, Gawarammana, IB, Shahmy, S, Chathuranga, U, Palangasinghe, C, Mostafa, A, Mackenzie, L, Roberts, MS, Buckley, NA & Mohamed, F 2025, 'Nephrotoxicity biomarkers following propanil (3,4-dichloropropionanilide) self-poisoning', Clinical Toxicology, vol. 63, no. 4, pp. 236-245. Open access
2024	Isoardi, KZ, Chiew, AL, Do, C, Humphreys, M, Mustafa, A, Roberts, MS & Isbister, GK 2024, 'A prospective study of acute propranolol overdose defining dose thresholds of severe toxicity (ATOM-9)', Clinical Toxicology, vol. 63, no. 1, pp. 1-9. 1 1
2024	Jia, W, Chandra, J, Teoh, SM, Tolley, L, Yang, H, Tse, BWC, Sokolowski, KA, Liang, X, Crawford, DHG, Steel, JC, Yu, C, Roberts, MS, Frazer, IH, Chen, Y, Wang, H & Yu, M 2024, 'STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines', Nano Letters: A Journal Dedicated to Nanoscience and Nanotechnology, vol. 24, no. 49, pp. 15588-15597.
2024	Mangion, SE, Mikkonen, A, Mackenzie, L, Roberts, MS & Maibach, H I 2024, 'Multiple topical product dermatitis: paradigms in understanding and future perspectives', JEADV CLINICAL PRACTICE, vol. 3, no. 1, pp. 49-64. Open access 1 12
2024	Mohammed, Y, Namjoshi, S, Jung, N, Windbergs, M, Benson, H, Grice, J, Raney, S & Roberts, M 2024, 'Topical semisolid drug product critical quality attributes with relevance to cutaneous bioavailability and pharmacokinetics: part I-bioequivalence of acyclovir topical creams', Pharmaceutical Research, vol. 41, no. 7, pp. 1507-1520. Open access 3 3
2024	Mohammed, YH, Namjoshi, S, Telaprolu, K, Jung, N, Shewan, H, Stokes, J, Benson, H, Grice, J, Raney, S, Rantou, E, Windbergs, M & Roberts, MS 2024, 'Impact of different packaging configurations on a topical cream product', Pharmaceutical Research, vol. 41, no. 10, pp. 2043-2056. Open access
2024	Namjoshi, SN, Telaprolu, K, Grice, JE, Benson, HA, Raney, S, Roberts, MS & Mohammed, YH 2024, 'Effect of 'in use' administration on topical product metamorphosis and skin permeation of Acyclovir creams: implications for Bioequivalence', Pharmaceutical Research, vol. 41, no. 12, pp. 2391-2401.
2024	Qiang, S, Mohamed, F, Raubenheimer, J, Buckley, NA, Roberts, MS & Mackenzie, L 2024, 'Clinical toxicology of acute glyphosate self-poisoning: impact of plasma concentrations of glyphosate, its metabolite and polyethoxylated tallow amine surfactants on the toxicity', Clinical Toxicology, vol. 62, no. 8, pp. 483-496. Open access 2
2023	Forouz, F, Mohammed, Y, Nejad, HS S, Roberts, MS & Grice, jE 2023, 'In vitro screening of topical formulation excipients for epithelial toxicity in cancerous and non-cancerous cell lines', EXCLI Journal, vol. 22, pp. 1173-1199. Open access 2
2023	Mangion, SE, Mackenzie, L, Roberts, MS & Holmes, AM 2023, 'Seborrheic dermatitis: topical therapeutics and formulation design', European Journal of Pharmaceutics and Biopharmaceutics, vol. 185, pp. 148-164. 16 11 86
2023	Mikkonen, AT, Martin, J, Upton, RN, Barker, AO, Brumley, CM, Taylor, MP, Mackenzie, L & Roberts, MS 2023, 'Spatio-temporal trends in livestock exposure to per- and polyfluoroalkyl substances (PFAS) inform risk assessment and management measures', Environmental Research, vol. 225, article no. 115518, pp. 1-14. Open access 11 12 38
2023	Mikkonen, AT, Martin, J, Upton, RN, Moenning, J-L, Numata, J, Taylor, MP, Roberts, MS & Mackenzie, L 2023, 'Dynamic exposure and body burden models for per- and polyfluoroalkyl substances (PFAS) enable management of food safety risks in cattle', Environment International: A Journal of Environmental Science, Risk & Health, vol. 180, article no. 108218, pp. 1-12. Open access 4 4 1
2023	Telaprolu, KC, Grice, JE, Mohammed, YH & Roberts, MS 2023, 'Human skin drug metabolism: relationships between methyl salicylate metabolism and esterase activities in IVPT skin membranes', Metabolites, vol. 13, no. 8, pp. 1-12. Open access 9 9
2023	Zhang, Q, Alinaghi, A, Williams, DB & Roberts, MS 2023, 'A thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: II. maximum flux and solute diffusion through stratum corneum lipids', International Journal of Pharmaceutics, vol. 631, article no. 122522, pp. 1-11. 1
2023	Zou, D, Wu, Z, Yi, X, Hui, Y, Yang, G, Liu, Y, Tengjisi, Wang, H, Brooks, A, Wang, H, Liu, X, Xu, ZP, Roberts, MS, Gao, H & Zhao, CX 2023, 'Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions', Proceedings of the National Academy of Sciences of USA, vol. 120, no. 1, pp. 1-12. Open access 42 47
2022	Al-Qurain, AA, Upton, RN, Tadros, R, Roberts, MS & Wiese, MD 2022, 'Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients', European Journal of Drug Metabolism and Pharmacokinetics, vol. 47, no. 3, pp. 387-402. Open access 4 4 1
2022	Alinaghi, A, Macedo, A, Cheruvu, HS, Holmes, A & Roberts, MS 2022, 'Human epidermal in vitro permeation test (IVPT) analyses of alcohols and steroids', International Journal of Pharmaceutics, vol. 627, article no. 122114, pp. 1-18. 11 6
2022	Alinaghi, A, Zhang, Q, Williams, DB, Mackenzie, L & Roberts, MS 2022, 'Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning', International Journal of Pharmaceutics, vol. 630, article no. 122424, pp. 1-10. 3 3
2022	Amarah, A, Hadgraft, J, Roberts, M & Anissimov, Y 2022, 'Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum', International Journal of Pharmaceutics, vol. 623, article no. 121902, pp. 1-10. 3 2
2022	Arora, S, Clarke, J, Tsakalozou, E, Ghosh, P, Alam, K, Grice, JE, Roberts, MS, Jamei, M & Polak, S 2022, 'Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model', Molecular Pharmaceutics, vol. 19, no. 9, pp. 3139-3152. 9 9
2022	Calcutt, JJ, Roberts, MS & Anissimov, YG 2022, 'Predicting viable skin concentration: modelling the subpapillary plexus', Pharmaceutical Research, vol. 39, no. 4, pp. 783-793. Open access 14 12
2022	Cheruvu, HS, Liu, X, Grice, JE & Roberts, MS 2022, 'An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions', Data in Brief, vol. 42, article no. 108242, pp. 1-9. Open access 9 7
2022	Hosseini, M, Roberts, MS, Aboofazeli, R & Moghimi, HR 2022, 'Measurement of Hansen Solubility Parameters of third-degree burn eschar', Burns, vol. 48, no. 4, pp.860-871. 6 5
2022	Jung, N, Namjoshi, S, Mohammed, Y, Grice, JE, Benson, HA, Raney, SG, Roberts, MS & Windbergs, M 2022, 'Application of confocal Raman microscopy for the characterization of topical semisolid formulations and their penetration into human skin ex vivo', Pharmaceutical Research, vol. 39, no. 5, pp. 935-948. Open access 25 24
2022	Liu, X, Cheruvu, HS, Anissimov, YG, van der Hoek, J, Tsakalozou, E, Ni, Z, Ghosh, P, Grice, JE & Roberts, MS 2022, 'Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing', International Journal of Pharmaceutics, vol. 625, article no. 122095, pp. 2-16. 2 2
2022	Mangion, SE, Sandiford, L, Mohammed, Y, Roberts, MS & Holmes, AM 2022, 'Multi-modal imaging to assess the follicular delivery of zinc pyrithione', Pharmaceutics, vol.14, no. 5, article no. 1076. Open access 8 8
2022	Mohammed, Y, Holmes, A, Kwok, PCL, Kumeria, T, Namjoshi, S, Imran, M, Matteucci, L, Ali, M, Tai, W, Benson, HA & Roberts, MS 2022, 'Advances and future perspectives in epithelial drug delivery', Advanced Drug Delivery Reviews, vol. 186, article no. 114293, pp. 1-38. 60 54
2022	Qiang, S, Mohamed, F, Mackenzie, L & Roberts, MS 2022, 'Rapid determination of polyethoxylated tallow amine surfactants in human plasma by LC-MSMS', Talanta, vol. 254, article no. 124115, pp. 1-12. 5 4 3
2022	Rambabu, L, Mohamed, F, Dhanarisi, J, Gawarammana, I, Raubenheimer, J, Mackenzie, L, Roberts, M, Buckley, N & Eddleston, M 2022, 'Acute phenthoate self-poisoning: a prospective case series', Clinical Toxicology, vol. 60, no. 2, pp. 214-220. Open access 1 3 4
2022	Rowland, M, Roberts, MS & Pang, KS 2022, 'In defense of current concepts and applications of clearance in drug development and therapeutics', Drug Metabolism and Disposition, vol. 50, no. 2, pp. 187-190. 11
2021	Abd, E, Gomes, J, Sales, C, Yousef, S, Forouz, F, Telaprolu, K, Roberts, M, Grice, J, Lopes, P, Leite-Silva, V & Andréo-Filho, N 2021, 'Deformable liposomes as enhancer of caffeine penetration through human skin in a Franz diffusion cell test', International Journal of Cosmetic Science, vol. 43, pp. 1-10. Open access 31 28
2021	Al-Qurain, AA, Upton, R, Williams, DB, Mackenzie, L, Phillips, C, Russell, PT, Tadros, R, Roberts, MS & Wiese, MD 2021, 'Population pharmacokinetic model of subcutaneous fentanyl in older acute care patients', European Journal of Clinical Pharmacology, vol. 77, no. 9, pp. 1357-1368. 2 2
2021	Al-Qurain, AA, Williams, DB, Mackenzie, L, Roberts, MS & Wiese, MD 2021, 'Simultaneous LC-MS/MS quantification of oxycodone, tramadol and fentanyl and their metabolites (noroxycodone, oxymorphone, O- desmethyltramadol, N- desmethyltramadol, and norfentanyl) in human plasma and whole blood collected via venepuncture and volumetric absorptive micro sampling', Journal of Pharmaceutical and Biomedical Analysis, vol. 203, article no. 114171, pp. 1-8. 11 9 2
2021	Buckley, NA, Fahim, M, Raubenheimer, J, Gawarammana, IB, Eddleston, M, Roberts, MS & Dawson, AH 2021, 'Case fatality of agricultural pesticides after self-poisoning in Sri Lanka: a prospective cohort study', Lancet Global Health, vol. 9, no. 6, pp. e854-e862. Open access 45 39
2021	Calcutt, JJ, Roberts, MS & Anissimov, YG 2021, 'Modelling drug transport within the viable skin - a review', Expert Opinion on Drug Metabolism and Toxicology, vol. 17, no. 1, pp. 105-119. Open access 13 11
2021	Dabbaghi, M, Namjoshi, S, Panchal, B, Grice, JE, Prakash, S, Roberts, MS & Mohammed, Y 2021, 'Viscoelastic and deformation characteristics of structurally different commercial topical systems', Pharmaceutics, vol. 13, no. 9, article no. 1351, pp. 1-11. Open access 48 43
2021	Gebremichael, LG, Suppiah, V, Wiese, MD, Mackenzie, L, Phillips, C, Williams, DB & Roberts, MS 2021, 'Efficacy and safety of statins in ethnic differences: a lesson for application in Indigenous Australian patient care', Pharmacogenomics, vol. 22, no. 9, pp. 553-571. 1 1
2021	Isoardi, K, Page, C, Roberts, M & Isbister, G 2021, 'Life-threatening triclopyr poisoning due to diethylene glycol monoethyl ether solvent', Clinical Toxicology, vol. 59, no 1, pp. 61-64. 2 2
2021	Khabir, Z, Holmes, AM, Lai, YJ, Liang, L, Deva, A, Polikarpov, MA, Roberts, MS & Zvyagin, A V 2021, 'Human epidermal zinc concentrations after topical application of ZnO nanoparticles in sunscreens', International Journal of Molecular Sciences, vol. 22, no. 22, article no. 12372. Open access 13 12
2021	Roberts, JA, Joynt, GM, Lee, A, Choi, G, Roberts, MS, Sinnollareddy, M & Lipman, J and 55 other authors 2021, 'The effect of renal replacement therapy and antibiotic dose on antibiotic concentrations in critically ill patients: data from the multinational sampling antibiotics in renal replacement therapy study', Clinical Infectious Diseases, vol. 72, no. 8, pp. 1369-1378. 104 95
2021	Roberts, MS, Cheruvu, HS, Mangion, SE, Alinaghi, A, Benson, HA, Mohammed, Y, Holmes, A, van der Hoek, J, Pastore, M & Grice, JE 2021, 'Topical drug delivery: history, percutaneous absorption, and product development', Advanced Drug Delivery Reviews, vol. 177, article no. 113929, pp. 1-43. Open access 146 134
2021	Zou, D, Wang, H, Liu, X, Xu, ZP, Roberts, MS & Zhao, CX 2021, 'Artificial cells for the treatment of liver diseases', Acta Biomaterialia, vol. 130, pp. 98-114. 11 11
2020	Al-Qurain, AA, Gebremichael, LG, Khan, MS, Williams, DB, Mackenzie, L, Phillips, C, Russell, P, Roberts, MS & Wiese, MD 2020, 'Prevalence and factors associated with analgesic prescribing in poly-medicated elderly patients', Drugs and Aging, vol. 37, no. 4, pp. 291-300. 21 21 44
2020	Cheruvu, HS, Liu, X, Grice, JE & Roberts, MS 2020, 'Modeling percutaneous absorption for successful drug discovery and development', Expert Opinion on Drug Discovery, vol. 15, no. 10, pp. 1181-1198. 19 17
2020	Ezati, N, Roberts, MS, Zhang, Q & Moghimi, HR 2020, 'Measurement of Hansen Solubility Parameters of human stratum corneum', Iranian Journal of Pharmaceutical Research, vol. 19, no. 3, pp. 572-578. Open access 12 12
2020	Forouz, F, Dabbaghi, M, Namjoshi, S, Mohammed, Y, Roberts, MS & Grice, JE 2020, 'Development of an oil-in-water self-emulsifying microemulsion for cutaneous delivery of rose Bengal: Investigation of anti-melanoma properties', Pharmaceutics, vol. 12, no. 10, pp. 1-17. Open access 17 16
2020	Holmes, AM, Kempson, I, Turnbull, T, Paterson, D & Roberts, MS 2020, 'Penetration of zinc into human skin after topical application of nano zinc oxide used in commercial sunscreen formulations', ACS Applied Bio Materials, vol. 3, no. 6, pp. 3640-3647. Open access 32 29 2
2020	Holmes, AM, Mackenzie, L & Roberts, MS 2020, 'Disposition and measured toxicity of zinc oxide nanoparticles and zinc ions against keratinocytes in cell culture and viable human epidermis', Nanotoxicology, vol. 14, no. 2, pp. 263-274. 37 34 1
2020	Liu, X, Yousef, S, Anissimov, YG, van der Hoek, J, Tsakalozou, E, Ni, Z, Grice, JE & Roberts, MS 2020, 'Diffusion modelling of percutaneous absorption kinetics. Predicting urinary excretion from in vitro skin permeation tests (IVPT) for an infinite dose', European Journal of Pharmaceutics and Biopharmaceutics, vol. 149, pp. 30-44. 6 5
2020	Mohammed, Y, Barkauskas, D, Holmes, A, Grice, J & Roberts, MS 2020, 'Noninvasive in vivo human multiphoton microscopy: a key method in proving nanoparticulate zinc oxide sunscreen safety', Journal of Biomedical Optics, vol. 25, no. 1, pp. 1-19. Open access 17 16
2020	Namjoshi, S, Dabbaghi, M, Roberts, MS, Grice, JE & Mohammed, Y 2020, 'Quality by design: development of the quality target product profile (QTPP) for semisolid topical products', Pharmaceutics, vol. 12, no. 3, pp. 1-12. Open access 95 70
2020	Nastiti, CM, Ponto, T, Mohammed, Y, Roberts, MS & Benson, HA 2020, 'Novel nanocarriers for targeted topical skin delivery of the antioxidant resveratrol', Pharmaceutics, vol. 12, no. 2, pp. 1-15. Open access 42 34
2019	Abd, E, Benson, HA, Mohammed, YH, Roberts, MS & Grice, JE 2019, 'Permeation mechanism of caffeine and naproxen through in vitro human epidermis: effect of vehicles and penetration enhancers', Skin Pharmacology and Physiology, vol. 32, no. 3, pp. 132-141. 22 19
2019	Abraham, J, Sinollareddy, M, Roberts, MS, Williams, P, Peake, SL, Lipman, J & Roberts, JA 2019, 'Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically patients with sepsis', International Journal of Antimicrobial Agents, vol. 53, no. 2, pp. 137-142. Open access 15 16
2019	Benson, HA, Grice, JE, Mohammed, Y, Namjoshi, S & Roberts, MS 2019, 'Topical and transdermal drug delivery: from simple potions to smart technologies', Current Drug Delivery, vol. 16, no. 5, pp. 444-460. Open access 226 182
2019	Haridass, IN, Wei, JC, Mohammed, YH, Crichton, ML, Anderson, CD, Henricson, J, Sanchez, WY, Meliga, SC, Grice, JE, Benson, HA, Kendall, MA & Roberts, MS 2019, 'Cellular metabolism and pore lifetime of human skin following microprojection array mediation', Journal of Controlled Release, vol. 306, pp. 59-68. Open access 22 19
2019	Latter, G, Grice, JE, Mohammed, Y, Roberts, MS & Benson, HA 2019, 'Targeted topical delivery of retinoids in the management of acne vulgaris: current formulations and novel delivery systems', Pharmaceutics, vol. 11, no. 10, article no. 490, pp. 1-26. Open access 65 49
2019	Mohammed, YH, Holmes, A, Haridass, IN, Sanchez, WY, Studier, H, Grice, JE, Benson, HA & Roberts, MS 2019, 'Support for the safe use of zinc oxide nanoparticle sunscreens: lack of skin penetration or cellular toxicity after repeated application in volunteers', Journal of Investigative Dermatology, vol. 139, no. 2, pp. 308-315. Open access 143 114
2019	Nastiti, C, Mohammed, Y, Telaprolu, K, Liang, X, Grice, J, Roberts, M & Benson, H 2019, 'Evaluation of quantum dot skin penetration in porcine skin: effect of age and anatomical site of topical application', Skin Pharmacology and Physiology, vol. 32, no. 4, pp. 182-191. 14 14
2019	Rainsford, K, Roberts, MS, Nencioni, A & Jones, C 2019, 'Rationale and evidence for the incorporation of heparin into the diclofenac epolamine medicated plaster', Current Medical Research and Opinion, vol. 35, no. 6, pp. 989-1002. Open access 2 1
2019	Sandiford, L, Holmes, AM, Mangion, SE, Mohammed, YH, Zvyagin, A V & Roberts, MS 2019, 'Optical characterization of zinc pyrithione', Photochemistry and Photobiology, vol. 95, no. 5, pp. 1142-1150. 9 8
2019	Schultz, HB, Vasani, RB, Holmes, AM, Roberts, MS & Voelcker, NH 2019, 'Stimulus-responsive antibiotic releasing systems for the treatment of wound infections', ACS Applied Bio Materials, vol. 2, no. 2, pp. 704-716. 22 22
2019	Vieira, CO, Grice, JE, Roberts, MS, Haridass, IN, Duque, MD, Lopes, PS, Leite-Silva, VR & Martins, TS 2019, 'ZnO:SBA-15 nanocomposites for potential use in sunscreen: preparation, properties, human skin penetration and toxicity', Skin Pharmacology and Physiology, vol. 32, no. 1, pp. 32-42. 23 20
2019	Wang, H, Lu, H, Yang, H, Zhang, X, Thompson, EW, Roberts, MS, Hu, Z, Liang, X & Li, X 2019, 'Impact of Age on Risk of Lymph Node Positivity in Patients with Colon Cancer', Journal Of Cancer, vol. 10, no. 9, pp. 2102-2108. Open access 8 9
2019	Xiao, W, Green, TI, Liang, X, Delint, RC, Perry, G, Roberts, MS, Le Vay, K, Back, CR, Ascione, R, Wang, H, Race, PR & Perriman, AW 2019, 'Designer artificial membrane binding proteins to direct stem cells to the myocardium', Chemical Science, vol. 10, no. 32, pp. 7610-7618. Open access 14 15
2019	Yousef, SA, Mohammed, YH, Namjoshi, S, Grice, JE, Benson, HA, Sakran, W & Roberts, MS 2019, 'Mechanistic evaluation of enhanced curcumin delivery through human skin in vitro from optimised nanoemulsion formulations fabricated with different penetration enhancers', Pharmaceutics, vol. 11, no. 12, article no. 639, pp. 1-20. Open access 49 44
2018	Abd, E, Benson, H, Roberts, M & Grice, J 2018, 'Follicular penetration of caffeine from topically applied nanoemulsion formulations containing penetration enhancers: in vitro human skin studies', Skin Pharmacology and Physiology, vol. 31, pp. 252-260. 41 39
2018	Abd, E, Benson, HA, Roberts, MS & Grice, JE 2018, 'Minoxidil skin delivery from nanoemulsion formulations containing eucalyptol or oleic acid: enhanced diffusivity and follicular targeting', Pharmaceutics, vol. 10, no.1, article no.19, pp. 1-12. Open access 60 56
2018	Alahakoon, C, Dassanayake, TL, Gawarammana, IB, Sedgwick, EM, Weerasinghe, VS, Abdalla, A, Roberts, MS & Buckley, NA 2018, 'Prediction of organophosphorus insecticide-induced intermediate syndrome with stimulated concentric needle single fibre electromyography', PLoS One, vol. 13, no. 9, pp. 1-19. Open access 14 12
2018	Amarah, A, Petlin, D, Grice, J, Hadgraft, J, Roberts, M & Anissimov, Y 2018, 'Compartmental modeling of skin transport', European Journal of Pharmaceutics and Biopharmaceutics, vol. 130, pp. 336-344. Open access 26 23
2018	Andréo-Filho, N, Bim, AVK, Kaneko, TM, Kitice, NA, Haridass, IN, Abd, E, Santos Lopes, P, Thakur, SS, Parekh, HS, Roberts, M, Grice, JE, Benson, HA & Leite-Silva, VR 2018, 'Development and evaluation of lipid nanoparticles containing natural botanical oil for sun protection: characterization and in vitro and in vivo human skin permeation and toxicity', Skin Pharmacology and Physiology, vol. 31, no. 1, pp. 1-9. 33 22
2018	Brooks, A, Futrega, K, Liang, X, Hu, X, Liu, X, Crawford, DH, Doran, MR, Roberts, MS & Wang, H 2018, 'Concise review: quantitative detection and modeling the in vivo kinetics of therapeutic mesenchymal stem/stromal cells', Stem Cells Translational Medicine, vol. 7, no. 1, pp. 78-86. Open access 44 41
2018	Chan, BS, Becker, T, Chiew, AL, Abdalla, AM, Robertson, TA, Liu, X, Roberts, MS & Buckley, NA 2018, 'Vasoplegic shock treated with methylene blue complicated by severe serotonin syndrome', Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology, vol. 14, no. 1, pp. 100-103. Open access 12 13
2018	Chiew, AL, Page, CB, Clancy, D, Mostafa, A, Roberts, MS & Isbister, GK 2018, '2-Methyl-4-chlorophenoxyacetic acid (MCPA) and bromoxynil herbicide ingestion', Clinical Toxicology, v. 56, no. 5, pp. 377-380. 5 5
2018	Chiew, AL, Wright, DF, Dobos, NM, McArdle, K, Mostafa, AA, Newth, A, Roberts, MS & Isbister, GK 2018, ''Massive' metformin overdose', British Journal of Clinical Pharmacology, vol. 84, no. 12, pp. 2923-2927. Open access 19 17
2018	Holmes, AM, Kempson, I, Turnbull, T, Paterson, D & Roberts, MS 2018, 'Imaging the penetration and distribution of zinc and zinc species after topical application of zinc pyrithione to human skin', Toxicology and Applied Pharmacology, vol. 343, pp. 40-47. 22 18 7
2018	Jin, W, Liang, X, Brooks, A, Futrega, K, Liu, X, Doran, MR, Simpson, MJ, Roberts, MS & Wang, H 2018, 'Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice', PEERJ, vol. 2018, no. 12, article no. e6072, pp. 1-17. Open access 61 61
2018	Junqueira Garcia, MT, de Vasconcellos, FLL, Raffier, CP, Roberts, MS, Grice, JE, Benson, HAE & Leite-Silva, VR 2018, 'Alternative methods to animal studies for the evaluation of topical/transdermal drug delivery systems', Current Topics in Medicinal Chemistry, vol. 18, no. 4, pp. 287-299. 8 7
2018	Khan, MS & Roberts, MS 2018, 'Challenges and innovations of drug delivery in older age', Advanced Drug Delivery Reviews, vol.135, pp. 3-38. Open access 56 48
2018	Le, T, Gong, Y, Wang, G, Davies, NM, Lillico, R, Lakowski, T, Roberts, MS & Burczynski, FJ 2018, 'The antioxidant activity of recombinant rat hepatic fatty acid binding protein t94a variant', Journal of Pharmacy and Pharmaceutical Sciences, vol. 21, no. 1s, pp. 309s-324s. Open access 1 1
2018	Morley, KC, Baillie, A, Fraser, I, Furneaux-Bate, A, Dore, G, Roberts, M, Abdalla, A, Nghi, P & Haber, PS 2018, 'Baclofen in the treatment of alcohol dependence with or without liver disease: multisite, randomised, double-blind, placebo-controlled trial', British Journal of Psychiatry, vol. 212, no. 6, pp. 362-369. Open access 105 95
2018	Rzhevskiy, AS, Telaprolu, K, Mohammed, YH, Grice, JE, Roberts, MS & Anissimov, YG 2018, 'Using a simple equation to predict the microporation-enhanced transdermal drug flux', European Journal of Pharmaceutics and Biopharmaceutics, vol. 127, pp. 12-18. Open access 8 8
2018	Sinnollareddy, MG, Roberts, MS, Lipman, J, Peake, SL & Roberts, JA 2018, 'Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration', Journal of Antimicrobial Chemotherapy, vol. 73, no. 6, pp. 147-1650. Open access 17 17
2018	Wang, H, Li, X, Tse, BWC, Yang, H, Thorling, CA, Liu, Y, Touraud, M, Chouane, JB, Liu, X, Roberts, MS & Liang, X 2018, 'Indocyanine green-incorporating nanoparticles for cancer theranostics', Theranostics, vol. 8, no. 5, pp. 1227-1242. Open access 297 282
2018	Wang, H, Yang, H, Xu, ZP, Liu, X, Roberts, MS & Liang, X 2018, 'Anionic long-circulating quantum dots for long-term intravital vascular imaging', Pharmaceutics, vol. 10, no. 4, article no. 244, pp. 1-8. Open access 13 10
2018	Warren, SC, Nobis, M, Magenau, A, Mohammed, YH, Herrmann, D, Moran, I, Vennin, C, Conway, JR, Melenec, P, Cox, TR, Wang, Y, Morton, JP, Welch, HC, Strathdee, D, Anderson, K I, Phan, TG, Roberts, MS & Timpson, P 2018, 'Removing physiological motion from intravital and clinical functional imaging data', eLife, vol. 7, pp. 1-37. Open access 40 36
2018	Wei, JC, Haridass, IN, Crichton, ML, Mohammed, YH, Meliga, SC, Sanchez, WY, Grice, JE, Benson, HA, Roberts, MS & Kendall, MA 2018, 'Space-and time-resolved investigation on diffusion kinetics of human skin following macromolecule delivery by microneedle arrays', Scientific Reports. Open access 32 29
2018	Yamada, M, Tayeb, H, Wang, H, Dang, N, Mohammed, YH, Osseiran, S, Belt, PJ, Roberts, M, Evans, CL, Sainsbury, F & Prow, TW 2018, 'Using elongated microparticles to enhance tailorable nanoemulsion delivery in excised human skin and volunteers', Journal of Controlled Release, vol. 288, pp. 264-276. Open access 24 23
2017	Berling, I, Mostafa, A, Grice, JE, Roberts, MS & Isbister, GK 2017, 'Warfarin poisoning with delayed rebound toxicity', Journal of Emergency Medicine, vol. 52, no. 2, pp. 194-196. Open access 6 7
2017	Cardon-Dunbar, A, Robertson, T, Roberts, MS & Isbister, GK 2017, 'Pramipexole overdose associated with visual hallucinations, agitation and myoclonus', Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology, 13, no. 4, pp. 343-346. Open access 1
2017	Gilbert, A V, Patel, BK, Roberts, MS, Williams, DB, Crofton, JH, Morris, NM, Wallace, J & Gilbert, AL 2017, 'An audit of medicines information quality in electronically generated discharge summaries: evidence to meet the Australian national safety and quality health service standards', Journal of Pharmacy Practice and Research, vol. 47, no. 5, pp. 355-364. 3
2017	Jayaweera, D, Islam, S, Gunja, N, Cowie, C, Broska, J, Poojara, L, Roberts, MS & Isbister, GK 2017, 'Chloroform ingestion causing severe gastrointestinal injury, hepatotoxicity and dermatitis confirmed with plasma chloroform concentrations', Clinical Toxicology, vol. 55, no. 2, pp. 147-150. 17 12
2017	Nastiti, CM, Ponto, T, Abd, E, Grice, JE, Benson, HA & Roberts, MS 2017, 'Topical nano and microemulsions for skin delivery', Pharmaceutics, vol. 9, no. 4, article no. 37, pp. 1-25. Open access 302 261
2017	Pastore, ML, Studier, H, Bonder, CS & Roberts, M 2017, 'Non-invasive metabolic imaging of melanoma progression', Experimental Dermatology, vol. 26, no. 7, pp. 607-614. 40 34 1
2017	Roberts, M, Mohammed, Y, Pastore, M, Namjoshi, S, Yousef, S, Alinaghi, A, Haridass, I, Abd, E, Leite-Silva, V, Benson, H & Grice, J 2017, 'Topical and cutaneous delivery using nanosystems', Journal of Controlled Release, vol. 247, pp. 86-105. Open access 236 208
2017	Sime, FB, Hahn, U, Warner, MS, Tiong, IS, Roberts, MS, Lipman, J, Peake, SL & Roberts, JA 2017, 'Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropenia', Antimicrobial Agents and Chemotherapy, vol. 61, no. 11, article no. e00311-17, pp. 1-7. Open access 27 24
2017	Wang, H, Liang, X, Gravot, G, Thorling, CA, Crawford, DH, Xu, ZP, Liu, X & Roberts, MS 2017, 'Visualizing liver anatomy, physiology and pharmacology using multiphoton microscopy', Journal of Biophotonics, vol. 10, no. 1, pp. 46-60. 38 36
2017	Wang, H, Thorling, CA, Xu, ZP, Crawford, DH, Liang, X, Liu, X & Roberts, MS 2017, 'Visualization and modeling of the In vivo distribution of mesenchymal stem cells', Current Protocols in Stem Cell Biology, vol. 43, pp. 2B.8.1-2B.8.17. 3
2017	Wang, H, Zhang, R, Bridle, KR, Jayachandran, A, Thomas, JA, Zhang, W, Yuan, J, Xu, ZP, Crawford, DH, Liang, X, Liu, X & Roberts, MS 2017, 'Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury', Scientific Reports, vol. 7, article no. 45374, pp. 1-11. Open access 46 42
2017	Wong, L, Wong, A, Robertson, T, Burns, K, Roberts, M & Isbister, G 2017, 'Severe hypertension and bradycardia secondary to midodrine overdose', Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology, vol. 13, no. 1, pp. 88-90. Open access 10 6
2017	Yousef, S, Mohammed, Y, Namjoshi, S, Grice, J, Sakran, W & Roberts, M 2017, 'Mechanistic evaluation of hydration effects on the human epidermal permeation of salicylate esters', AAPS Journal, vol. 19, no. 1, pp. 180-190. 27 28
2016	Abd, E, Namjoshi, S, Mohammed, YH, Roberts, MS & Grice, JE 2016, 'Synergistic skin penetration enhancer and nanoemulsion formulations promote the human epidermal permeation of caffeine and naproxen', Journal of Pharmaceutical Sciences, vol. 105, no. 1, pp. 212-220. 71 69
2016	Abd, E, Roberts, M & Grice, J 2016, 'A comparison of the penetration and permeation of caffeine into and through human epidermis after application in various vesicle formulations', Skin Pharmacology and Physiology, vol. 29, no. 1, pp. 24-30. Open access 41 35
2016	Abd, E, Yousef, SA, Pastore, MN, Telaprolu, K, Mohammed, Y, Namjoshi, S, Grice, JE & Roberts, M 2016, 'Skin models for the testing of transdermal drugs', Clinical Pharmacology: Advances and Applications, vol. 8, pp. 163-176. Open access 367 190
2016	Alobaid, AS, Brinkmann, A, Frey, OR, Roehr, AC, Luque, S, Grau, S, Wong, G, Abdul-Aziz, M-H, Roberts, MS, Lipman, J & Roberts, JA 2016, 'What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?', Journal of Antimicrobial Chemotherapy, vol. 71, no. 3, pp. 696-702. Open access 34 30
2016	Alobaid, AS, Wallis, SC, Jarrett, P, Starr, T, Stuart, J, Lassig-Smith, M, Mejia, JLO, Roberts, MS, Sinnollareddy, MG, Roger, C, Lipman, J & Roberts, JA 2016, 'Effect of obesity on the population pharmacokinetics of fluconazole in critically Ill patients', Antimicrobial Agents and Chemotherapy, vol. 60, no. 11, pp. 6550-6557. Open access 47 43
2016	Chandrasekaran, NC, Sanchez, WY, Mohammed, YH, Grice, JE, Roberts, MS & Barnard, RT 2016, 'Permeation of topically applied Magnesium ions through human skin is facilitated by hair follicles', Magnesium Research, vol. 29, no. 2, pp. 35-42. Open access 24 22
2016	Holmes, AM, Lim, J, Studier, H & Roberts, MS 2016, 'Varying the morphology of silver nanoparticles results in differential toxicity against micro-organisms, HaCaT keratinocytes and affects skin deposition', Nanotoxicology, vol. 10, no. 10, pp. 1503-1514. 41 39
2016	Holmes, AM, Song, Z, Moghimi, HR & Roberts, M 2016, 'Relative penetration of zinc oxide and zinc ions into human skin after application of different zinc oxide formulations', ACS Nano, vol. 10, no. 2, pp. 1810-1819. 98 90
2016	Isbister, GK, Ang, K, Gorman, K, Cooper, J, Mostafa, A & Roberts, MS 2016, 'Zero-order metoprolol pharmacokinetics after therapeutic doses: severe toxicity and cardiogenic shock', Clinical Toxicology, vol. 54, no. 9, pp. 881-885. 7 6
2016	Lamb, T, Selvarajah, LR, Mohamed, F, Jayamanne, S, Gawarammana, I, Mostafa, A, Buckley, NA, Roberts, MS & Eddleston, M 2016, 'High lethality and minimal variation after acute self-poisoning with carbamate insecticides in Sri Lanka: implications for global suicide prevention', Clinical Toxicology, vol. 54, no. 8, pp. 624-631. Open access 25 17
2016	Leite-Silva, V, Sanchez, W, Studier, H, Liu, D, Mohammed, Y, Holmes, A, Ryan, E, Haridass, I, Chandrasekaran, N, Becker, W, Grice, J, Benson, H & Roberts, M 2016, 'Human skin penetration and local effects of topical nano zinc oxide after occlusion and barrier impairment', European Journal of Pharmaceutics and Biopharmaceutics, vol. 104, pp.140-147. Open access 60 54
2016	Leite-Silva, VR, Liu, DC, Sanchez, WY, Studier, H, Mohammed, YH, Holmes, A, Becker, W, Grice, JE, Benson, HA & Roberts, MS 2016, 'Effect of flexing and massage on in vivo human skin penetration and toxicity of zinc oxide nanoparticles', Nanomedicine, vol. 11, no. 10, pp. 1193-1205. 54 47
2016	Liang, X, Wang, H, Grice, JE, Li, L, Liu, X, Xu, ZP & Roberts, MS 2016, 'Physiologically based pharmacokinetic model for long-circulating inorganic nanoparticles', Nano Letters: A Journal Dedicated to Nanoscience and Nanotechnology, vol. 16, no. 2, pp. 939-945. 50 44
2016	Liang, X, Wang, H, Zhu, Y, Zhang, R, Cogger, VC, Liu, X, Xu, ZP, Grice, JE & Roberts, MS 2016, 'Short-and long-term tracking of anionic ultrasmall nanoparticles in kidney', ACS Nano, vol. 10, no. 1, pp. 387-395. 108 103
2016	Page, CB, Mostafa, A, Saiao, A, Grice, JE, Roberts, MS & Isbister, GK 2016, 'Cardiovascular toxicity with levetiracetam overdose', Clinical Toxicology, vol. 54, no. 2, pp. 152-154. 17 13
2016	Roberts, JA, Choi, GY, Joynt, GM, Paul, SK, Deans, R, Peake, S, Cole, L, Stephens, D, Bellomo, R, Turnidge, J, Wallis, SC, Roberts, MS, Roberts, DM, Lassig-Smith, M, Starr, T & Lipman, J 2016, 'SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients', BMC Infectious Diseases, vol. 16, no. 103, pp. 1-8. Open access 14 13
2016	Sinnollareddy, MG, Roberts, MS, Lipman, J, Lassig-Smith, M, Starr, T, Robertson, T, Peake, SL & Roberts, JA 2016, 'In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis', Antimicrobial Agents and Chemotherapy, vol. 60, no. 2, pp. 827-832. Open access 18 18
2016	Wang, H, Liang, X, Xu, ZP, Crawford, DH, Liu, X & Roberts, M 2016, 'A physiologically based kinetic model for elucidating the in vivo distribution of administered mesenchymal stem cells', Scientific Reports, vol. 6, article no. 22293, pp. 1-12. Open access 29 26
2016	Yousef, S, Liu, X, Mostafa, A, Mohammed, Y, Grice, JE, Anissimov, YG, Sakran, W & Roberts, MS 2016, 'Estimating maximal In vitro skin permeation flux from studies using non-sink receptor phase conditions', Pharmaceutical Research, vol. 33, no. 9, pp. 2180-2194. 20 19
2015	Arab, H-A, Walker, N I, Cheung, K, Hickman, PE, Potter, JM, Kadkhodaee, M & Roberts, MS 2015, 'Free radical scavengers improve liver function but not morphological changes induced by reperfusion injury', Journal of Investigative Surgery, vol. 28, no. 2, pp. 77-85. 1 1
2015	Berling, I, Buckley, NA, Mostafa, A, Downes, MA, Grice, J, Medley, G, Roberts, MS & Isbister, GK 2015, '2-Methyl-4-chlorophenoxyacetic acid and bromoxynil herbicide death', Clinical Toxicology, vol. 53, no. 5, pp. 486-488. Open access 6 5
2015	Downes, MA, Berling, IL, Mostafa, A, Grice, J, Roberts, MS & Isbister, GK 2015, 'Acute behavioural disturbance associated with phenibut purchased via an internet supplier', Clinical Toxicology, vol. 53, no. 7, pp. 636-638. 28 26
2015	Gordon, S, Daneshian, M, Bouwstra, J, Caloni, F, Roberts, MS & Lehr, CM and 23 other authors 2015, 'Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology', ALTEX-Alternatives to Animal Experimentation, vol. 32, no. 4, pp. 327-378. Open access 126 106
2015	Liang, XL, Grice, JE, Zhu, Y, Liu, D, Sanchez, WY, Li, Z, Crawford, DH, Le Couteur, DG, Cogger, VC, Liu, X, Xu, ZP & Roberts, MS 2015, 'Intravital multiphoton imaging of the selective uptake of water-dispersible quantum dots into sunusoidal liver cells', Small, vol. 11, no. 14, pp. 1711-1720. 37 38
2015	Mahmood, AH, Liu, X, Grice, JE, Medley, GA & Roberts, MS 2015, 'Using deconvolution to understand the mechanism for variable plasma concentration-time profiles after intramuscular injection', International Journal of Pharmaceutics, vol. 481, no. 1-2, pp. 71-78. 6 5
2015	Michael, AP, Mostafa, A, Cooper, J, Grice, J, Roberts, MS & Isbister, GK 2015, 'The pharmacokinetics and pharmacodynamics of severe aldicarb toxicity after overdose', Clinical Toxicology, vol. 53, no. 7, pp. 633-635. 3 2
2015	Pastore, MN, Kalia, YN, Horstmann, M & Roberts, MS 2015, 'Transdermal patches: history, development and pharmacology', British Journal of Pharmacology, vol. 172, no. 9, pp. 2179-2209. Open access 423 342
2015	Reeve, E, Andrews, JM, Wiese, MD, Hendrix, I, Roberts, MS & Shakib, S 2015, 'Feasibility of a patient-centered deprescribing process to reduce inappropriate use of proton pump inhibitors', Annals of Pharmacotherapy, vol. 49, no. 1, pp. 29-38. 73 56 7
2015	Roberts, DM, Xin, L, Roberts, J, Nair, P, Cole, L, Roberts, M, Lipman, J & Bellomo, R 2015, 'A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics', Critical Care, vol. 19, pp. 1-9. Open access 115 110
2015	Roberts, JA, Udy, AA, Jarrett, P, Wallis, SC, Hope, WW, Sharma, R, Kirkpatrick, CM, Kruger, PS, Roberts, MS & Lipman, J 2015, 'Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-traumacritically ill patients', Journal of Antimicrobial Chemotherapy, vol. 70, no. 5, pp. 1495-1502. Open access 60 58
2015	Sime, FB, Roberts, M, Tiong, IS, Gardner, J, Lehman, S, Peake, S, Hahn, U, Warner, M & Roberts, J 2015, 'Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies', Antimicrobial Agents and Chemotherapy, v 59, no. 9, pp.5463-5469. Open access 23 23
2015	Sime, FB, Roberts, M, Tiong, IS, Gardner, JH, Lehman, S, Peake, SL, Hahn, U, Warner, MS & Roberts, JA 2015, 'Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial', Journal of Antimicrobial Chemotherapy, vol. 70, no. 8, pp. 2369-2375. Open access 71 64
2015	Sime, FBR, Roberts, MS & Roberts, J 2015, 'Optimization of dosing regimens and dosing in special populations', Clinical Microbiology and Infection, vol. 21, no. 10, pp. 886-893. Open access 77 67
2015	Sinnollareddy, MG, Roberts, M, Lipman, J, Peake, SL & Roberts, J 2015, 'Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: Use of microdialysis', International Journal of Antimicrobial Agents, vol. 46, no. 1, pp. 121-124. 6 6
2015	Sinnollareddy, MG, Roberts, MS, Lipman, J, Robertson, TA, Peake, SL & Roberts, JA 2015, 'Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration', International Journal of Antimicrobial Agents, vol. 45, no. 2, pp. 192-195. 10 10
2015	Skinner, K, Saiao, A, Mostafa, A, Soderstrom, J, Medley, G, Roberts, MS & Isbister, GK 2015, 'Isoniazid poisoning: pharmacokinetics and effect of hemodialysis in a massive ingestion', Hemodialysis International, vol. 19, no. 4, pp. E37-E40. 11 9
2015	Thorling, CA, Jin, L, Weiss, M, Crawford, D, Liu, X, Burczynski, FJ, Liu, D, Wang, H & Roberts, MS 2015, 'Assessing steatotic liver function after ischemia-reperfusion injury by in vivo multiphoton imaging of fluorescein disposition', Drug Metabolism and Disposition, vol. 43, no. 1, pp. 154-162. Open access 20 20
2015	Udy, AA, Lipman, J, Jarrett, P, Klein, K, Wallis, SC, Patel, K, Kirkpatrick, CM, Kruger, PS, Paterson, DL, Roberts, MS & Roberts, JA 2015, 'Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?', Critical Care, vol. 19, no. 1, article no. 28, pp. 1-9. Open access 120 109
2015	Wang, H, Liang, X, Mohammed, YH, Thomas, JA, Bridle, KR, Thorling, CA, Grice, JE, Xu, ZP, Liu, X, Crawford, DHG & Roberts, MS 2015, 'Real-time histology in liver disease usingmultiphoton microscopy with fluorescencelifetime imaging', Biomedical Optics Express, vol. 9, no. 3, pp. 780-792. Open access 52 48
2015	Wang, H, Thorling, CA, Liang, X, Bridle, KR, Grice, JE, Zhu, Y, Crawford, DHG, Xu, ZP, Liu, X & Roberts, MS 2015, 'Diagnostic imaging and therapeutic application of nanoparticles targeting the liver', Journal of Materials Chemistry B, vol. 3, pp. 939-958. 147 130
2014	Chandrasekaran, NC, Weir, C, Alfraji, S, Grice, J, Roberts, MS & Barnard, RT 2014, 'Effects of magnesium deficiency-more than skin deep', Experimental Biology and Medicine, vol. 239, no. 10, pp. 1280-1291. 18 17
2014	Krishnan, G, Roberts, M, Grice, J, Anissimov, Y, Moghimi, H & Benson, H 2014, 'Iontophoretic skin permeation of peptides : an investigation into the influence of molecular properties, iontophoretic conditions and formulation parameters', Drug Delivery and Translational Research, vol. 4, no. 3, pp. 222-232. Open access 31 26
2014	Kuswahyuning, R & Roberts, MS 2014, 'Concentration dependency in nicotine skin penetration flux from aqueous solutions reflects vehicle induced changes in nicotine stratum corneum retention', Pharmaceutical Research, vol. 31, no. 6, pp. 1501-1511. 13 9
2014	Liu, X, Kruger, P, Maibach, H, Colditz, PB & Roberts, MS 2014, 'Using skin for drug delivery and diagnosis in the critically ill', Advanced Drug Delivery Reviews, vol. 77, pp. 40-49. 33 29
2014	McNeilly, CL, Crichton, ML, Primiero, CA, Frazer, IH, Roberts, MS & Kendall, MA 2014, 'Microprojection arrays to immunise at mucosal surfaces', Journal of Controlled Release, vol. 196, pp. 252-260. 32 32
2014	Mohammed, YH, Yamada, M, Lin, LL, Grice, JE, Roberts, MS, Raphael, AP, Benson, HA & Prow, TW 2014, 'Microneedle enhanced delivery of cosmeceutically relevant peptides in human skin', PLoS One, vol. 9, no. 7, article no. e101956, pp. 1-9. Open access 73 68
2014	Reeve, E, Shakib, S, Hendrix, I, Roberts, MS & Wiese, MD 2014, 'Review of deprescribing processes and development of an evidence-based, patient-centred deprescribing process', British Journal of Clinical Pharmacology, vol. 78, no. 4, pp. 738-747. Open access 275 254
2014	Reeve, E, Shakib, S, Hendrix, I, Roberts, MS & Wiese, MD 2014, 'The benefits and harms of deprescribing', Medical Journal of Australia, vol. 201, no. 7, pp. 386-389. Open access 87 63
2014	Sime, FB, Roberts, MS, Roberts, JA & Robertson, TA 2014, 'Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies', Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 960, pp. 134-144. Open access 92 87
2014	Sime, FB, Roberts, MS, Warner, MS, Hahn, U, Robertson, TA, Yeend, S, Phay, A, Lehman, S, Lipman, J, Peake, SL & Roberts, JA 2014, 'Altered pharmacokinetics of piperacillin in febrile neutropenic patients with haematological malignancy', Antimicrobial Agents and Chemotherapy, vol. 58, no. 6, pp. 3533-3537. Open access 36 35
2014	Thorling, CA, Crawford, D, Burczynski, FJ, Liu, X, Liau, I & Roberts, MS 2014, 'Multiphoton microscopy in defining liver function', Journal of Biomedical Optics, vol. 19, no. 9, article no. 090901 pp. 090901.1-090901.11. Open access 37 31
2014	Thorling, CA, Roberts, MS, Liu, X, Fletcher, LM, Crawford, D & Burczynski, FJ 2014, 'Effects of long-term hepatic ischemia-reperfusion injury on the function of P-glycoprotein in vivo in rats', Journal of Pharmacy and Pharmaceutical Sciences, vol. 17 no. 1, pp. 121-135. Open access 8 8
2014	Wong, G, Brinkman, A, Benefield, RJ, Carlier, M, Roberts, MS, Robertson, TA, Sime, FB & Roberts, JA and 13 other authors 2014, 'An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units', Journal of Antimicrobial Chemotherapy, vol. 69, no. 5, article no. dkt523, pp. 1416-1423. Open access 191 173
2014	Wunnapuk, K, Gobe, G, Endre, Z, Peake, P, Grice, JE, Roberts, MS, Buckley, NA & Liu, X 2014, 'Use of a glyphosate-based herbicide-induced nephrotoxicity model to investigate a panel of kidney injury biomarkers', Toxicology Letters, vol. 225, no. 1, pp. 192-200. Open access 49 45
2014	Wunnapuk, K, Liu, X, Gobe, GC, Endre, ZH, Peake, PW, Grice, JE, Roberts, MS & Buckley, NA 2014, 'Kidney biomarkers in MCPA-induced acute kidney injury in rats : reduced clearance enhances early biomarker performance', Toxicology Letters, vol. 225, no. 3, pp. 467-478. Open access 10 10
2014	Wunnapuk, K, Mohammed, F, Gawarammana, I, Liu, X, Verbeeck, RK, Buckley, NA, Roberts, MS & Musuamba, FT 2014, 'Prediction of paraquat exposure and toxicity in clinically ill poisoned patients : a model based approach', British Journal of Clinical Pharmacology, vol. 78, no. 4, pp. 855-866. Open access 43 33
2013	Anissimov, YG, Jepps, OG, Dancik, Y & Roberts, MS 2013, 'Mathematical and pharmacokinetic modelling of epidermal and dermal transport processes', Advanced Drug Delivery Reviews, vol. 65, no. 2, pp. 169-190. 126 110
2013	Arab, H-A, Cheung, K, Hickman, PE, Potter, JM, Walker, N I & Roberts, MS 2013, 'A comparison of hepatic ischemia/hypoxia-reperfusion injury models', Journal of Pharmacological and Toxicological Methods, vol. 68, no. 3, pp. 349-356. 2 2
2013	Dancik, Y, Favre, A, Loy, CJ, Zvyagin, A V & Roberts, MS 2013, 'Use of multiphoton tomography and fluorescence lifetime imaging to investigate skin pigmentation in vivo', Journal of Biomedical Optics, vol. 18, no. 2, article no. 026022, pp. 1-13. Open access 67 56
2013	Jepps, OG, Dancik, Y, Anissimov, YG & Roberts, MS 2013, 'Modeling the human skin barrier - towards a better understanding of dermal absorption', Advanced Drug Delivery Reviews, vol. 65, no. 2, pp. 152-168. 210 195
2013	Krishnan, G, Grice, JE, Roberts, MS, Benson, HA & Prow, TW 2013, 'Enhanced sonophoretic delivery of 5-aminolevulinic acid : preliminary human ex vivo permeation data', Skin Research and Technology, vol. 19, no. 1, pp. e283-e289. 21 19
2013	Kruger, P, Bailey, M, Bellomo, R, Cooper, DJ, Harward, M, Higgins, A, Howe, B, Jones, D, Joyce, C, Kostner, K, McNeil, J, Nichol, A, Roberts, MS, Syres, G & Venkatesh, B 2013, 'A multicenter randomized trial of atorvastatin therapy in intensive care patients with severe sepsis', American Journal of Respiratory and Critical Care Medicine, vol. 187, no. 7, pp. 743-750. 191 182
2013	Leite-Silva, VR, Le Lamer, M, Sanchez, WY, Liu, DC, Sanchez, WH, Morrow, I, Martin, D, Silva, HD, Prow, TW, Grice, JE & Roberts, MS 2013, 'The effect of formulation on the penetration of coated and uncoated zinc oxide nanoparticles into the viable epidermis of human skin in vivo', European Journal of Pharmaceutics and Biopharmaceutics, vol. 84, no. 2, pp. 297-308. 114 98
2013	Liang, XW, Xu, ZP, Grice, JE, Zvyagin, A, Roberts, MS & Liu, X 2013, 'Penetration of nanoparticles into human skin', Current Pharmaceutical Design, vol. 19, no. 35, pp. 6353-6366. 64 52
2013	Liu, X, Jin, L, Upham, JW & Roberts, MS 2013, 'The development of models for the evaluation of pulmonary drug disposition', Expert Opinion on Drug Metabolism and Toxicology, vol. 9, no. 4, pp. 487-505. 14 12
2013	Mahmood, A, Grice, JE, Roberts, MS & Prow, TW 2013, 'Feasibility of multiphoton microscopy-based quantification of antibiotic uptake into neutrophil granulocytes', Journal of Biomedical Optics, vol. 18, no. 7, pp.1-6. Open access 1 1
2013	Mutalik, S, Parekh, H, Anissimov, Y, Grice, J & Roberts, MS 2013, 'Iontophoresis-mediated transdermal permeation of peptide dendrimers across human epidermis', Skin Pharmacology and Physiology, vol. 26, no. 3, pp. 127-138. 48 46
2013	Raphael, AP, Sundh, D, Grice, JE, Roberts, MS, Soyer, HP & Prow, TW 2013, 'Zinc oxide nanoparticle removal from wounded human skin', Nanomedicine, vol. 8, no. 11, pp. 1751-1761. 26 22
2013	Reeve, E, Shakib, S, Hendrix, I, Roberts, MS & Wiese, MD 2013, 'Development and validation of the patients' attitudes towards deprescribing (PATD) questionnaire', International Journal of Clinical Pharmacy, vol. 35, no. 1, pp. 51-56. 90 86
2013	Reeve, E, To, J, Hendrix, I, Shakib, S, Roberts, MS & Wiese, MD 2013, 'Patient barriers to and enablers of deprescribing: a systematic review', Drugs and Aging, vol. 30, no. 10, pp. 793-807. Open access 390 367
2013	Reeve, E, Wiese, MD, Hendrix, I, Roberts, MS & Shakib, S 2013, 'People's attitudes, beliefs, and experiences regarding polypharmacy and willingness to deprescribe', Journal of the American Geriatrics Society, vol. 61, no. 9, pp. 1508-1514. 192 170
2013	Roberts, MS 2013, 'Solute-vehicle-skin interactions in percutaneous absorption: the principles and the people', Skin Pharmacology and Physiology, vol. 26, no. 4, pp. 356-370. Open access 20 16
2013	Robertson, TA, Bunel, F & Roberts, MS 2013, 'Fluorescein derivatives in intravital fluorescence imaging', Cells, vol. 2, no. 3, pp. 591-606. Open access 51
2013	Sanchez, W, Obispo, C, Ryan, E, Grice, JE & Roberts, MS 2013, 'Changes in the redox state and endogenous fluorescence of in vivo human skin due to intrinsic and photo-aging, measured by multiphoton tomography with fluorescence lifetime imaging', Journal of Biomedical Optics, vol. 18, no. 6, pp. 1-13. Open access 28 23
2013	Song, Z, Anissimov, YG, Zhao, J, Nechaev, A V, Nadort, A, Jin, D, Prow, TW, Roberts, MS & Zvyagin, A V 2013, 'Background free imaging of upconversion nanoparticle distribution in human skin', Journal of Biomedical Optics, vol. 18, no. 6, pp. 1-10. Open access 44 36
2013	Thorling, CA, Liu, X, Burczynski, FJ, Fletcher, LM, Roberts, MS & Sanchez, WY 2013, 'Intravital multiphoton microscopy can model uptake and excretion of fluorescein in hepatic ischemia-reperfusion injury', Journal of Biomedical Optics, vol. 18, no. 10, article no. 101306, pp. 1-11. Open access 26 25
2013	Weiss, M, Liu, X, Thompson, CA & Roberts, MS 2013, 'Functional characterization of hepatic transporters using intravital microscopy', European Journal of Pharmaceutical Sciences, vol. 49, no. 5, pp. 845-849. 9 8
2013	Wunnapuk, K, Liu, X, Peake, P, Gobe, G, Endre, Z, Grice, JE, Roberts, MS & Buckley, NA 2013, 'Renal biomarkers predict nephrotoxicity after paraquat', Toxicology Letters, vol. 222, no. 3, pp. 280-288. 47 42
2013	Zhang, Q, Li, P, Liu, D & Roberts, MS 2013, 'Effect of vehicles on the maximum transepidermal flux of similar size phenolic compounds', Pharmaceutical Research, vol. 30, no. 1, pp. 32-40. 28 25
2012	Anissimov, YG, Zhao, X, Roberts, MS & Zvyagin, A V 2012, 'Fluorescence recovery after photo-bleaching as a method to determine local diffusion coefficient in the stratum corneum', International Journal of Pharmaceutics, vol. 435, no. 1, pp. 93-97. Open access 18 17
2012	Dancik, Y, Anissimov, YG, Jepps, OG & Roberts, MS 2012, 'Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application', British Journal of Clinical Pharmacology, vol. 73, no. 4, pp. 564-578. Open access 50 44
2012	Gilbert, A, Patel, B, Morrow, M, Williams, D, Roberts, MS & Gilbert, AL 2012, 'Providing community-based health practitioners with timely and accurate discharge medicines information', BMC Health Services Research, vol. 12, article no. 453 pp. 1-7. Open access 6 5
2012	Kaur, S, Roberts, JA & Roberts, MS 2012, 'Evaluation of medication-related problems in medication reviews : a comparative perspective', Annals of Pharmacotherapy, vol. 46, no. 7-8, pp. 972-982. Open access 17 17
2012	Leite-Silva, VR, de Almeida, MM, Fradin, A, Grice, JE & Roberts, MS 2012, 'Delivery of drugs applied topically to the skin', Expert Review of Dermatology, vol. 7, no. 4, pp. 383-397. 63
2012	Li, P, Robertson, TA, Zhang, Q, Fletcher, LM, Crawford, DH, Weise, M & Roberts, MS 2012, 'Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage', Pharmaceutical Research, vol. 29, no. 6, pp. 1658-1669. 11 10
2012	Li, P, Weise, M & Roberts, MS 2012, 'Hepatic interaction between quinidine and digoxin: role of inhibition of sinusoidal Na+/K+ ATPase digoxin binding', European Journal of Pharmaceutical Sciences, vol. 47, no. 2, pp. 506-511. 2 2
2012	Liu, DC, Raphael, AP, Sundh, D, Grice, JE, Soyer, H, Roberts, M & Prow, TW 2012, 'The human stratum corneum prevents small gold nanoparticle penetration and their potential toxic metabolic consequences', Journal of Nanomaterials, vol. 2012, article no. 721706, pp. 1-8. Open access 24 21
2012	Liu, X, Kruger, PS, Weise, M & Roberts, MS 2012, 'The pharmacokinetics and pharmacodynamics of cisatracurium in critically ill patients with severe sepsis', British Journal of Clinical Pharmacology, vol. 73, no. 5, pp. 741-749. Open access 13 12
2012	Liu, X, Thorling, CA, Jin, L & Roberts, MS 2012, 'Intravital multiphoton imaging of rhodamine 123 in the rat liver after intravenous dosing', IntraVital, vol. 1, no. 1, pp. 54-59. Open access
2012	Mahmood, AH, Medley, GA, Grice, JE, Liu, X & Roberts, MS 2012, 'Determination of trovafloxacin and marbofloxacin in sheep plasma samples by HPLC using UV detection', Journal of Pharmaceutical and Biomedical Analysis, vol. 62, pp. 220-223. 19 15
2012	Prow, TW, Monteriro-Riviere, NA, Inman, AO, Grice, JE, Chen, X, Zhao, X, Sanchez, WH, Gierden, A, Kendall, MA, Zvyagin, A V, Erdmann, D, Riviere, JE & Roberts, MS 2012, 'Quantum dot penetration into viable human skin', Nanotoxicology, vol. 6, no. 2, pp. 173-185. 99 83
2012	Roberts, DM, Roberts, JA, Roberts, MS, Liu, X, Nair, P, Cole, L, Lipman, J & Bellomo, R 2012, 'Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: a multicentre pharmacokinetic study', Critical Care Medicine, vol. 40, no. 5, pp. 1523-1528. 179 174
2012	Sime, FB, Roberts, MS, Peake, SL, Lipman, J & Roberts, JA 2012, 'Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review', Annals of Intensive Care, vol. 2, article no. 35, pp. 1-11. Open access 163 137
2012	Sinnollareddy, MG, Peake, S, Roberts, MS, Lipman, J & Roberts, J 2012, 'Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review', International Journal of Antimicrobial Agents, vol. 39, no. 1, pp. 1-10. 46 42
2012	Sinnollareddy, MG, Roberts, MS, Lipman, J & Roberts, JA 2012, 'ß-lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization : a structured review', Clinical and Experimental Pharmacology and Physiology, vol. 39, no. 6, pp. 489-496. Open access 75 69
2012	Weise, M, Li, P & Roberts, MS 2012, 'Estimation of sinusoidal flow heterogeneity in normal and diseased rat livers from tracer dilution data using a fractal model', Microcirculation, vol. 19, no. 8, pp. 723-728. 3 3
2012	Wiechers, J, Watkinson, A, Cross, S & Roberts, M 2012, 'Predicting skin penetration of actives from complex cosmetic formulations: an evaluation of inter formulation and inter active effects during formulation optimization for transdermal delivery', International Journal of Cosmetic Science, vol. 34, no. 6, pp. 525-535. Open access 23 19
2011	Anissimov, YG & Roberts, MS 2011, 'Modelling dermal drug distribution after topical application in human', Pharmaceutical Research, vol. 28, no. 9, pp. 2119-2129. 51 41
2011	Davies, PG, Venkatesh, B, Morgan, TJ, Presneill, JJ, Kruger, PS, Thomas, BJ, Roberts, MS & Mundy, J 2011, 'Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution', Critical Care, vol. 15, no. 1, pp. R21-1-R21-8. Open access 39 33
2011	Douglas, A, Altukroni, M, Udy, AA, Roberts, MS, Taraporewalla, K, Jenkins, J, Lipman, J & Roberts, JA 2011, 'The pharmacokinetics of cefazolin in patients undergoing elective & semi-elective abdominal aortic aneurysm open repair surgery', BMC Anesthesiology, vol. 11, article no. 5, pp. 1-5. Open access 8 7
2011	Douglas, A, Udy, AA, Wallis, SC, Jarrett, P, Stuart, J, Lassig-Smith, M, Deans, R, Roberts, MS, Taraporewalla, K, Jenkins, J, Medley, G, Lipman, J & Roberts, JA 2011, 'Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery', Antimicrobial Agents and Chemotherapy, vol. 55, no. 11, pp. 5238-5242. Open access 70 64
2011	Fanning, KJ, Robertson, TA, Prins, JB & Roberts, MS 2011, 'Changes in antibiotic distribution due to pancreatitis', Antimicrobial Agents and Chemotherapy, vol. 55, no. 6, pp. 3008-3011. Open access 4 2
2011	König, K, Raphael, AP, Lin, L, Grice, JE, Soyer, HP, Breuing, HG, Roberts, MS & Prow, TW 2011, 'Applications of multiphoton tomographs and femtosecond laser nanoprocessing microscopes in drug delivery research', Advanced Drug Delivery Reviews, vol. 63, no. 4-5, pp. 388-404. 97 83
2011	Krishnan, G, Roberts, MS, Grice, J, Anissimov, YG & Benson, HA 2011, 'Enhanced transdermal delivery of 5-aminolevulinic acid and a dipeptide by iontophoresis', Biopolymers, vol. 96, no. 2, pp. 166-171. 21 20
2011	Kruger, P, Harward, M, Jones, M, Joyce, C, Kostner, K, Roberts, MS & Venkatesh, B 2011, 'Continuation of statin therapy in patients with presumed infection:a randomized controlled trial', American Journal of Respiratory and Critical Care Medicine, vol. 183, no. 6, pp. 774-781. Open access 96 94
2011	Labouta, H I, Liu, DC, Lin, LL, Butler, MK, Grice, JE, Raphael, AP, Kraus, T, El-Khordagui, LK, Soyer, HP, Roberts, MS, Schneider, M & Prow, TW 2011, 'Gold nanoparticle penetration and reduced metabolism in human skin by toluene', Pharmaceutical Research, vol. 28, pp. 2931-2944. 84 75
2011	Li, P, Robertson, TA, Thompson, CA, Zhang, Q, Fletcher, LM, Crawford, DH & Roberts, MS 2011, 'Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis', Drug Metabolism and Disposition, vol. 39, no. 4, pp. 571-579. 28 28
2011	Lin, LL, Grice, JE, Butler, MK, Zvyagin, A V, Becker, W, Robertson, TA, Soyer, HP, Roberts, MS & Prow, TW 2011, 'Time-correlated single photon counting for simultaneous monitoring of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin', Pharmaceutical Research, vol. 28, pp. 2920-2930. 102 80
2011	Liu, X, Grice, JE, Lademann, J, Otberg, N, Trauer, S, Patzelt, A & Roberts, MS 2011, 'Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man', British Journal of Clinical Pharmacology, vol. 72, no. 5, pp. 768-774. Open access 92 77
2011	Liu, X, Kruger, PS & Roberts, MS 2011, 'How to measure pharmacokinetics in critically ill patients?', Current Pharmaceutical Biotechnology, vol. 12, no. 12, pp. 2037-2043. 6 5
2011	Mitragotri, S, Anissimov, YG, Bunge, AL, Frasch, HF, Guy, RH, Hadgraft, J, Kasting, GB, Lane, ME & Roberts, MS 2011, 'Mathematical models of skin permeability: an overview', International Journal of Pharmaceutics, vol. 418, no. 1, pp. 115-129. Open access 316 279
2011	Monajjemzadeh, F, Hassanzadeh, D, Valizadeh, H, Siahi-Shadbad, MR, Mojarrad, JS, Robertson, TA & Roberts, MS 2011, 'Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation / Part 2', Pharmazeutische Industrie, vol. 73, no. 2, pp. 376-382. 2 2
2011	Monajjemzadeh, F, Hassanzadeh, D, Valizadeh, H, Siahi-Shadbad, MR, Mojarrad, JS, Robertson, TA & Roberts, MS 2011, 'Detection of gabapentin-lactose maillard reaction product (Schiff's base): application to solid dosage form preformulation / Part 1', Pharmazeutische Industrie, vol. 73, no. 1, pp. 174-177. 13 10
2011	Mostafa, A, Medley, G, Roberts, DM, Mohamed, MS, Elshanawani, AA, Roberts, MS & Liu, X 2011, 'Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry', Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 879, no. 23, pp. 2234-2238. Open access 18 17
2011	Prow, TW, Grice, JE, Lin, LL, Faye, R, Butler, M, Becker, W, Wurm, EM, Yoong, C, Robertson, TA, Soyer, HP & Roberts, MS 2011, 'Nanoparticles and microparticles for skin drug delivery', Advanced Drug Delivery Reviews, vol. 63, no. 6, pp. 470-491. 732 629
2011	Roberts, DM, Wilks, MF, Roberts, MS, Swaminathan, R, Mohamed, F, Dawson, A & Buckley, NA 2011, 'Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning', Toxicology Letters, vol. 202, no. 1, pp. 69-74. Open access 43 42
2011	Roberts, JA, Roberts, MS, Semark, A, Udy, AA, Kirkpatrick, CM, Paterson, DL, Roberts, MJ, Kruger, P & Lipman, J 2011, 'Antibiotic dosing in the 'at risk' critically ill patient : linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients', BMC Anesthesiology, vol. 11, article no. 3, pp. 1-7. Open access 45 41
2011	Roberts, MS, Dancik, Y, Prow, TW, Thompson, CA, Lin, LL, Grice, JE, Robertson, TA, König, K & Becker, W 2011, 'Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy', European Journal of Pharmaceutics and Biopharmaceutics, vol. 77, no. 3, pp. 469-488. 155 128
2011	Roberts, MS, Liu, X, Zou, Y, Siebert, GA, Chang, P, Whitehouse, MW, Fletcher, L & Crawford, DH 2011, 'Effect of adjuvant-induced systemic inflammation in rats on hepatic disposition kinetics of taurocholate', American Journal of Physiology: Gastrointestinal and Liver Physiology, vol. 300, no. 1, pp. G130-G136. Open access 6 7
2011	Sinnollareddy, M, Peake, SL, Roberts, MS, Playford, EG, Lipman, J & Roberts, JA 2011, 'Pharmacokinetic evaluation of fluconazole in critically ill patients', Expert Opinion on Drug Metabolism and Toxicology, vol. 7, no. 11, pp. 1431-1440. 12 11
2011	Song, Z, Kelf, T, Sanchez, WH, Roberts, MS, Rička, J, Frenz, M & Zvyagin, A 2011, 'Characterization of optical properties of ZnO nanoparticles for quantitative imaging of transdermal transport', Biomedical Optics Express, vol. 2, no. 12, pp. 3321-3333. Open access 106 87
2011	Thorling, CA, Dancik, Y, Hupple, CW, Medley, G, Liu, X, Zvyagin, A V, Robertson, TA, Burczynski, FJ & Roberts, MS 2011, 'Multiphoton microscopy and fluorescence lifetime imaging provide a novel method in studying drug distribution and metabolism in the rat liver in vivo', Journal of Biomedical Optics, vol. 16, no. 8, pp. 086013.1-086013.7. Open access 17 14
2011	Thorling, CA, Liu, X, Burczynski, FJ, Fletcher, LM, Gobe, GC & Roberts, MS 2011, 'Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats', Journal of Biomedical Optics, vol. 16, no. 11, article no. 116011, pp. 1-8. Open access 31 27
2011	Wunnapuk, K, Medley, GA, Liu, X, Grice, JE, Jayasinghe, S, Gawarammana, I, Buckley, NA & Roberts, MS 2011, 'Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: application to experimental and clinical toxicological studies', Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 879, no. 28, pp. 3047-3052. Open access 42 40
2011	Zhang, Q, Li, P & Roberts, MS 2011, 'Maximum transepidermal flux for similar size phenolic compounds is enhanced by solvent uptake into the skin', Journal of Controlled Release, vol. 154, no. 1, pp. 50-57. Open access 47 41
2011	Zhou, F, Zhang, J, Li, P, Niu, F, Wu, X, Wang, G & Roberts, MS 2011, 'Toward a new age of cellular pharmacokinetics in drug discovery', Drug Metabolism Reviews, vol. 43, no. 3, pp. 335-345. 56 46
2010	Brownlie, C, Roberts, MS, Grice, JE & Cross, S 2010, 'The application of molecular structural predictors of intestinal absorption to screening of compounds for transdermal penetration', Journal of Pharmacy and Pharmacology, vol. 62, no. 6, pp. 750-755. 11 9
2010	Dalley, A, Lipman, J, Roberts, MS, Roberts, J & Kirkpatrick, CM 2010, 'First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis', International Journal of Antimicrobial Agents, vol. 35, no. 2, pp. 156-163. 162 153
2010	Fernando, GJ, Chen, X, Prow, TW, Crichton, ML, Fairmaid, EJ, Roberts, MS, Frazer, IH, Brown, LE & Kendall, MA 2010, 'Potent immunity of low doses of influenza vaccine by probalistic guided micro-targeted skin delivery in a mouse model', PLoS One, vol. 5, no. 4. Open access 150 135
2010	Gawarammana, IB, Medley, G, Mohamed, f, Jayamanne, S, Dawson, A, Roberts, D & Roberts, MS 2010, 'Acute human self-poisoning with bispyribac-containing herbicide Nominee (R): a prospective observational study', Clinical Toxicology, vol. 48, no. 3, pp. 198-202. Open access 7 5
2010	Geusens, B, Van Gele, M, Braat, S, De Smedt, SC, Stuart, MC, Prow, TW, Sanchez, W, Roberts, MS, Sanders, NN & Lambert, J 2010, 'Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in the viable epidermis of ex vivo human skin', Advanced Functional Materials, vol. 20, no. 23, pp. 4077-4090. 82 66
2010	Hickman, P, Potter, J, Aroney, C, Koerbin, G, Southcott, E, Wu, AH & Roberts, MS 2010, 'Cardiac troponin may be released by ischemia alone, without necrosis', Clinica Chimica Acta, vol. 411, no. 5-6, pp. 318-323. 232 212
2010	Popov, AP, Zvyagin, A, Lademann, J, Roberts, M, Sanchez, WY, Priezzhev, AU & Myllyla, R 2010, 'Designing inorganic light-protective skin nanotechnology products', Journal of Biomedical Nanotechnology, vol. 6, no. SI5, pp. 432-451. 60 51
2010	Prow, TW, Chen, X, Prow, NA, Fernando, GJ, Tan, CS, Raphael, AP, Chang, D, Ruutu, MP, Jenkins, DW, Pyke, A, Crichton, ML, Raphaelli, K, Goh, LY, Frazer, IH, Roberts, MS, Gardner, J, Khromykh, AA, Suhrbier, A, Hall, RA & Kendall, MA 2010, 'Nanopatch-targeted skin vaccination against West Nile virus and Chikungunya virus in mice', Small, vol. 6, no. 16, pp. 1776-1784. 155 142
2010	Roberts, MS, Chandler, S, MacDonald, G, Green, B & Elliott, G 2010, 'Quantifying Pain Relief Following Administration of a Novel Formulation of Paracetamol (Acetaminophen)', Journal of Clinical Pharmacology, vol. 50, no. 12, pp. 1406-1413. 5 3
2010	Roberts, MS, Kim, S, Park, S, Ropella, G & Hunt, A 2010, 'Tracing Multiscale Mechanisms of Drug Disposition in Normal and Diseased Livers', Journal of Pharmacology and Experimental Therapeutics, vol. 334, no. 1, pp. 124-136. 28 23
2010	Sanchez, WY, Prow, TW, Sanchez, WH, Grice, JE & Roberts, MS 2010, 'Analysis of the metabolic deterioration of ex vivo skin from ischemic necrosis through the imaging of intracellular NAD(P)H by multiphoton tomography and fluorescence lifetime imaging microscopy', Journal of Biomedical Optics, vol. 15, no. 4, pp. 046008.1-046008.11. Open access 83 61
2010	Ulldemolins, M, Ungerer, J, Roberts, MS, Roberts, J, McWhinney, B, Paterson, D & Lipman, J 2010, 'Therapeutic drug monitoring of ß-lactams in critically ill patients: proof of concept', International Journal of Antimicrobial Agents, vol. 36, no. 4, pp. 332-339. 309 286
2010	Weiner, N, Roberts, MS, Cross, S, Lockwood, P, Grice, JE & Ciotti, S 2010, 'Relative Uptake of Minoxidil into Appendages and Stratum Corenum and Permeation through Human Skin In Vitro', Journal of Pharmaceutical Sciences, vol. 99, no. 2, pp. 712-718. 53 39
2010	Weiss, M, Roberts, MS & Li, P 2010, 'An Improved Nonlinear Model Describing the Hepatic Pharmacokinetics of Digoxin: Evidence for Two Functionally Different Uptake Systems and Saturable Binding', Pharmaceutical Research, vol. 27, no. 9, pp. 1999-2007. 14 13
2010	Weiss, M, Yang, Y, Khlentzos, AM, Nikolovski, J, Zou, Y, Liu, X & Roberts, MS 2010, 'Nitric oxide induced sinusoidal relaxation after a propranolol priming dose in the perfused rat liver reduces propranolol availability on subsequent dosing ', Clinical and Experimental Pharmacology and Physiology, vol. 37, no. 10, pp. 1028-1033.
2010	Xia, C-h, Sun, J-g, Wang, G-j, Shang, L-l, Zhang, X-x, Zhang, R, Peng, Y, Wang, X-j, Hao, H-p, Xie, L & Roberts, MS 2010, 'Herb-drug interactions : in vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in rats', Planta Medica: Natural Products and Medicinal Plant Research, vol. 76, no. 3, pp. 245-250. 46 35
2010	Xu, S, Huang, W, Yang, Y, Yang, S, Roberts, MS, He, S, Liu, X & Zhang, X 2010, 'Mechanisms of transforming growth factor b1/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts', British Journal of Dermatology, vol. 162, no. 3, pp. 538-546. 115 104
2010	Yang, Y, Roberts, MS, Xu, S, Huang, W, He, S, Liu, X & Zhang, X 2010, 'Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-B/Smad in HepG2 cell', Journal of Gastroenterology and Hepatology, vol. 25, no. 2, pp. 420-426. 64 62
2010	Zou, Y-H, Liu, X, Khlentzos, AM, Asadian, P, Li, P, Thorling, CA, Robertson, TA, Fletcher, LM, Crawford, DHG & Roberts, MS 2010, 'Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model', Drug Metabolism and Pharmacokinetics, vol. 25, no. 5, pp. 442-449. Open access 5 4
2009	Chen, X, Prow, TW, Crichton, ML, Jenkins, DW, Roberts, MS, Frazer, IH, Fernando, GJ & Kendall, MA 2009, 'Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin', Journal of Controlled Release, vol. 139, no. 3, pp. 212-220. 179 160
2009	Li, P, Wang, G-J, Robertson, TA & Roberts, MS 2009, 'Liver transporters in hepatic drug disposition: an update', Current Drug Metabolism, vol. 10, no. 5, pp. 482-498. 33 30
2009	Liu, X, Wang, JY, Khlentzos, AM, Fontaine, F, Nikolovski, J, Goh, L-A & Roberts, MS 2009, 'Influence of perfusate composition on drug disposition in the in-situ perfused rat lung', International Journal of Pharmaceutics, vol. 382, no. 1-2, pp. 192-197. 7 7
2009	Monajjemzadeh, F, Hassanzadeh, D, Valizadeh, H, Siahi-Shadbad, MR, Mojarrad, JS, Robertson, TA & Roberts, MS 2009, 'Compatibility studies of acyclovir and lactose in physical mixtures and commercial tablets', European Journal of Pharmaceutics and Biopharmaceutics, vol. 73, no. 3, pp. 404-413. 84 63
2009	Qian, Z, Grice, JE, Li, P, Jepps, OG, Wang, G-J & Roberts, MS 2009, 'Skin solubility determines maximum transepidermal flux for similar size molecules', Pharmaceutical Research, vol. 26, no. 8, pp. 1974-1985. 80 70
2009	Roberts, JA, Roberts, MS, Robertson, TA, Dalley, AJ & Lipman, J 2009, 'Piperacillin penetration into tissue of critically ill patients with sepsis-bolus versus continuous administration?', Critical Care Medicine, vol. 37, no. 3, pp. 926-933. 161 157
2008	Dufour, E, Roberts, MS & Nohynek, G 2008, 'Nanotechnology, cosmetics and the skin: is there a health risk?', Skin Pharmacology and Physiology, vol. 21, no. 3, pp. 136-149. 285 241
2008	Poenicke, K, Hung, D, Roberts, MS & Weiss, M 2008, 'Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin', European Journal of Pharmaceutical Sciences, vol. 34, no. 4-5, pp. 345-350. 14 14
2008	Roberts, MS & Cross, S 2008, 'Use of In vitro human skin membranes to model and predict the effect of changing blood flow on the flux and retention of topically applied solutes.', Journal of Pharmaceutical Sciences, vol. 97, no. 8, pp. 3442-3450. 13 11
2008	Roberts, MS, Anissimov, Y, Cross, S, Winckle, G & Wise, G 2008, 'An integrated pharmacokinetic and imagine evaluation of vehicle effects on solute human epidermal flux and, retention characteristics', Pharmaceutical Research, vol. 25, no. 1, pp. 158-166. 11 8
2008	Roberts, MS, Hunt, A, Yan, L, Ropella, G & Park, S 2008, 'Modeling and simulation of hepatic drug disposition using a physiologically based, multi-agent in silico liver', Pharmaceutical Research, vol. 25, no. 5, pp. 1023-1036. 41 34
2008	Roberts, MS, Kim, S, Ropella, G & Park, S 2008, 'Computational Strategies Unravel and Trace How Liver Disease Changes Hepatic Drug Disposition', Journal of Pharmacology and Experimental Therapeutics, vol. 328, no. 1, pp. 294-305. 22 19
2008	Roberts, MS, Russel, M, Southwell, I & Cross, S 2008, 'Human skin penetration of the major components of Australian tea tree oil applied in its pure form and as a 20% solution in vitro.', European Journal of Pharmaceutics and Biopharmaceutics, vol. 69, no. 1, pp. 214-222. 41 28
2008	Robertson, TA, Roberts, J, Lipman, J, Cross, S & Roberts, MS 2008, 'A novel way to investigate the effects of plasma exchange on antibiotic levels- the use of microdialysis', International Journal of Antimicrobial Agents, vol. 31, no. 3, pp. 240-244. 18 31
2008	Sanchez, W, Zhao, X, Zvyagin, A, Zou, Y, Roberts, M, Robertson, TA, Thorling, C & Roberts, MS 2008, 'In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver'.

Conferences

Year	Output
2016	Liang, X, Wang, H, Liu, X & Roberts, M 2016, 'Quantitative optical imaging of paracetamol-induced metabolism changes in the liver', SPIE, vol. 10013, article no. 100131H, pp. 1-4. Open access 1
2016	Liu, X, Liang, X, Wang, H, Roberts, DM & Roberts, MS 2016, 'Multiphoton imaging for assessing renal disposition in acute kidney injury', SPIE BioPhotonics Australasia, SPIE, vol. 10013, article no. 100131F, pp. 1-4. Open access
2016	Thorling (Thompson), C, Wang, H, Liu, X, Liang, X, Crawford, DH & Roberts, MS 2016, 'Non-invasive assessment of the liver using imaging', SPIE, vol. 10013, article no. 100131J, pp. 1-5. Open access
2016	Thorling, CA, Studier, H, Crawford, D & Roberts, MS 2016, 'Using multiphoton fluorescence lifetime imaging to characterize liver damage and fluorescein disposition in liver in vivo', Multiphoton Microscopy in the Biomedical Sciences XVI, SPIE, vol. 9712, article no. 97120Y, pp. 1-12. 1
2016	Wang, H, Jayachandran, A, Gravot, G, Liang, X, Thorling, CA, Zhang, R, Liu, X & Roberts, MS 2016, 'In vivo quantitative visualization of hypochlorous acid in the liver using a novel selective two-photon fluorescent probe', SPIE BioPhotonics Australasia, SPIE. Open access
2008	Prow, TW, Chen, X, Crichton, M, Tiwari, Y, Gradassi, F, Raphelli, K, Mahony, D, Fernando, G, Roberts, MS & Kendall, MA 2008, 'Targeted epidermal delivery of vaccines from coated micro-nanoprojection patches', International Conference on Nanoscience and Nanotechnology, ICONN 2008, IEEE, no. article no. 4639262, pp. 125-128. 2 1
2008	Roberts, MS 2008, 'Quantum Dots.'.

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Acino Pharma AG	GERMANY
ACT Pathology	AUSTRALIA
Alexandria University	EGYPT
An-eX Analytical Services Ltd	UNITED KINGDOM
Anhui Medical University	CHINA
ARC Centre of Excellence for Nanoscale BioPhotonics	AUSTRALIA
Austin Health	AUSTRALIA
Austin Hospital	AUSTRALIA
Australian National University	AUSTRALIA
Australian Synchrotron	AUSTRALIA
Autonomous University of Barcelona	SPAIN
Babraham Institute	UNITED KINGDOM
Beatson Institute for Cancer Research	UNITED KINGDOM
Becker & Hickl GmbH	GERMANY
Becker and Hickl GmbH	GERMANY
Becker Hickl GmbH	GERMANY
Blacktown Hospital	AUSTRALIA
Bundaberg Hospital	AUSTRALIA
Calvary Mater Hospital	AUSTRALIA
Canberra Hospital	AUSTRALIA
Central Adelaide Local Health Network Incorporated	AUSTRALIA
Central Queensland University	AUSTRALIA
Changzheng Hospital	CHINA
Charite - Medical University of Berlin	GERMANY
Chiang Mai University	THAILAND
Childrens Hospital at Westmead	AUSTRALIA
China Pharmaceutical University	CHINA
Colorado School of Mines	UNITED STATES
Curtin University	AUSTRALIA
Dalian University of Technology	CHINA
Duke University	UNITED STATES
Environment Protection Authority Victoria	AUSTRALIA
Federal Institute for Risk Assessment	GERMANY
Federal University of Sao Paulo	BRAZIL
Federal University of São Paulo (Brazil)	BRAZIL
Food and Drug Administration	THAILAND
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP	GERMANY
Garvan Institute of Medical Research	AUSTRALIA
General Hospital of Heidenheim	GERMANY
Genoskin	FRANCE
Ghent University	BELGIUM
Goethe University Frankfurt	GERMANY
Goethe University, Frankfurt	GERMANY
Greenslopes Private Hospital	AUSTRALIA
Griffith University	AUSTRALIA
Helwan University	EGYPT
Heriot-Watt University	UNITED KINGDOM
Holy Spirit Northside Hospital	AUSTRALIA
IBSA Institut Biochimique	SWITZERLAND
IBSA Pharma	UNITED STATES
Imaginot Pty Ltd	AUSTRALIA
INM Institute	GERMANY
Institut Polytechnique Lasalle-Beauvais	FRANCE
Ipswich Hospital	AUSTRALIA
Jamia Hamdard	INDIA
JenLab GmbH	GERMANY
Joanneum Research	AUSTRIA
John Fawkner Private Hospital	AUSTRALIA
Johnson & Johnson	UNITED STATES
Johnson and Johnson Asia Pacific	UNITED STATES
King Saud University	SAUDI ARABIA
Kurchatov Institute	RUSSIAN FEDERATION
Leiden University	NETHERLANDS
Linköping University	SWEDEN
Liverpool Hospital Elizabeth	AUSTRALIA
Lomonosov Moscow State University	RUSSIAN FEDERATION
Macquarie	AUSTRALIA
Macquarie University	AUSTRALIA
Manipal University	INDIA
Martin Luther University Halle-Wittenberg	GERMANY
Massachusetts General Hospital	UNITED STATES
Monash University	AUSTRALIA
Moscow State University	RUSSIAN FEDERATION
Nanjing University	CHINA
Nanjing University of Science and Technology	CHINA
Nanyang Technological University	SINGAPORE
National Chiao Tung University	TAIWAN
National Institute for Occupational Safety and Health	UNITED STATES
Nepean Hospital	AUSTRALIA
Nimes University Hospital	FRANCE
North Carolina State University - Raleigh	UNITED STATES
Peking University	CHINA
Pfizer Global Research and Development	UNITED STATES
Prince of Wales Hospital	AUSTRALIA
Princess Alexandra Hospital	AUSTRALIA
Princess Alexandra Hospital Brisbane	AUSTRALIA
Private Individual	UNITED KINGDOM
Proctor and Gamble Eurocor	BELGIUM
Public Health Virology, Queensland Health Forensic and Scientific Services	AUSTRALIA
QIMR Berghofer Medical Research Institute	AUSTRALIA
Queensland Health	AUSTRALIA
Queensland Institute of Medical Research	AUSTRALIA
Queensland University of Technology	AUSTRALIA
Quest Pharmaceutical	UNITED STATES
Repatriation General Hospital	AUSTRALIA
Rhodes University	SOUTH AFRICA
Royal Adelaide Hospital	AUSTRALIA
Royal Alexandra Hospital for Children	AUSTRALIA
Royal Brisbane & Women's Hospital	AUSTRALIA
Royal Brisbane and Women's Hospital	AUSTRALIA
Royal Darwin Hospital	AUSTRALIA
Royal North Shore Hospital	AUSTRALIA
Royal Perth Hospital	AUSTRALIA
Royal Prince Alfred Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
Saarland University	GERMANY
Sechenov First Moscow State Medical University	RUSSIAN FEDERATION
Sechenov University	RUSSIAN FEDERATION
Second Military Medical University	CHINA
Senversa Pty Ltd	AUSTRALIA
Shahid Beheshti University	IRAN
Shahid Beheshti University of Medical Sciences	IRAN
Shanghai Jiao Tong University	CHINA
Shanghai University	CHINA
Sheffield Hallam University	UNITED KINGDOM
Shimadzu Australasia	AUSTRALIA
Soochow University	TAIWAN
Sorbonne University (France)	FRANCE
St Vincent's Hospital	AUSTRALIA
St. Thomas Hospital	UNITED STATES
Storith Consulting Ltd.	UNITED KINGDOM
Sydney Children's Hospital, Randwick	AUSTRALIA
Sydney Local Health District	AUSTRALIA
Tabriz University of Medical Sciences	IRAN
Tehran University of Medical Sciences	IRAN
Temasek Polytechnic	SINGAPORE
The Alfred Hospital	AUSTRALIA
The Chinese University of Hong Kong (CUHK)	CHINA
The Queen Elizabeth Hospital	AUSTRALIA
Translational Research Institute	UNITED STATES
United States Food and Drug Administration	UNITED STATES
Universita Degli Studi di Milano	ITALY
Universite de Rennes	FRANCE
University Claude Bernard	FRANCE
University College London	UNITED KINGDOM
University Libre Bruxelles	BELGIUM
University of Adelaide	AUSTRALIA
University of Alberta	CANADA
University of Athens	GREECE
University of Basel	SWITZERLAND
University of Bath	UNITED KINGDOM
University of Bern	SWITZERLAND
University of Bristol	UNITED KINGDOM
University of California	UNITED STATES
University of California San Francisco	UNITED STATES
University of California System	UNITED STATES
University of Cincinnati	UNITED STATES
University of Edinburgh	UNITED KINGDOM
University of Groningen	NETHERLANDS
University of Guelph	CANADA
University of Halle-Wittenberg	GERMANY
University of Kelaniya	SRI LANKA
University of Konstanz	GERMANY
University of Lausanne	SWITZERLAND
University of Liverpool	UNITED KINGDOM
University of London	UNITED KINGDOM
University of Manchester	UNITED KINGDOM
University of Manitoba	CANADA
University of Maryland	UNITED STATES
University of Melbourne	AUSTRALIA
University of Michigan	UNITED STATES
University of New South Wales	AUSTRALIA
University of Newcastle	AUSTRALIA
University of Otago	NEW ZEALAND
University of Oulu	FINLAND
University of Peradeniya	SRI LANKA
University of Pittsburgh	UNITED STATES
University of Queensland	AUSTRALIA
University of Rennes 1	FRANCE
University of Sao Paulo	BRAZIL
University of South Australia	AUSTRALIA
University of Southampton	UNITED KINGDOM
University of Southern Queensland	AUSTRALIA
University of Sydney	AUSTRALIA
University of Tasmania	AUSTRALIA
University of Tehran	IRAN
University of Toronto	CANADA
University of Utah	UNITED STATES
University of Wollongong	AUSTRALIA
US Food and Drug Administration	UNITED STATES
Wake Forest University School of Medicine	UNITED STATES
Western Health Victoria	AUSTRALIA
Western Sydney Health	AUSTRALIA
Westmead Hospital	AUSTRALIA
Wollongong Hospital	AUSTRALIA
Women's and Children's Hospital	AUSTRALIA
Zagazig University	EGYPT

External engagement & recognition

Engagement/recognition	Year
Senior Principal Research Fellow National Health and Medical Research Council (NHMRC)	2018
Advisory Board Member, Cosmetic Advisory Committee Australian Government	2017
Consultant, Chemical Safety and Environmental Health Branch Australian Government	2017
Member International Skin Pharmacology and Physiology	2017
Member National Industrial Chemicals Notification and Assessment Scheme (NICNAS)	2017
Member Pharmaceutical Society of Australia	2017
Member American Association of Pharmaceutical Scientists	2017
Member Australasian Pharmaceutical Science Association (APSA)	2017
Member Controlled Release Society	2017
Member Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT)	2017
Member, Pharmaceutical Subcommittee (PSC) Australian Drug Evaluation Committee (ADEC)	2017
Senior Principal Research Fellow National Health and Medical Research Council (NHMRC)	2017
Visiting Professor University of Lyon, France	2017
Fellow Australian Academy of Health and Medical Science	2015
Fellowship National Health and Medical Research Council (NHMRC)	2013
Fellowship worth $1.6 million National Health and Medical Research Council (NHMRC)	2011
Senior Principal Research Fellow National Health and Medical Research Council (NHMRC)	2011
Senior Principal Research Fellow National Health and Medical Research Council (NHMRC)	2009

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
Comparison of skin morphological and physiological profiles in health and disease	Current
Assessing patterns and appropriateness of prescription of medications in elderly patients admitted to South Australian Hospitals	Completed
Development and feasibility of a patient-centred deprescribing process	Completed
Does vitamin D deficiency contribute to endothelial dysfunction?	Completed
Getting through the skin¿s formidable barrier ¿ understanding the role of solute structure, skin morphology and formulation in skin delivery	Completed
Improving antifungal use in the critically ill: a pharmacokinetic/pharmacodynamic approach	Completed
In vitro dissolution testing in relation to in vivo performance of drugs	Completed
Intracellular signal transduction and modulation of P2Y12 receptor signaling in health and disease	Completed
Investigation of the toxicokinetics of per- and polyfluoroalkyl substances (PFAS) in cattle and application to risk assessment	Completed
Liquid chromatography-tandem mass spectrometry based bioanalysis for assessment of glyphosate-surfactant product exposure: clinical toxicology and pharmacokinetics	Completed
Liquid chromatography-tandem mass spectrometry-based bioanalysis to assess toxicological and therapeutic aspects in human disease conditions	Completed
Opioid prescribing in older patients; pharmacoepidemiology and pharmacokinetics	Completed
Percutaneous absorption: towards a mechanistic understanding of skin disease, topical product and end-user effects	Completed
Skin deep ¿ understanding the transport within the skin and nail for formulation design	Completed
Structural determinants and formulation effects on percutaneous absorption	Completed
The impact and outcomes of services provided by the pharmacist to improve quality use of medicines in Australian population	Completed
The role of formulations in skin delivery	Completed
The use of multiphoton microscopy in the study of transmembrane drug transport in hepatic ischemia reperfusion injury	Completed
Therapeutic drug monitoring of beta-lactam antibiotics in patients at high risk of therapeutic failure: a pharmacokinetic and pharmacodynamic investigation	Completed

Professor Michael Roberts

About me

About me

UniSA Clinical & Health Sciences

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Highlights

Projects

Outputs

Books

Chapters

Journal Articles

Conferences

Current research & highlights

External engagement & recognition

Collaborations

Collaborations

External engagement & recognition

Senior Principal Research Fellow

Advisory Board Member, Cosmetic Advisory Committee

Consultant, Chemical Safety and Environmental Health Branch

Member

Member

Member

Member

Member

Member

Member

Member, Pharmaceutical Subcommittee (PSC)

Senior Principal Research Fellow

Visiting Professor

Fellow

Fellowship

Fellowship worth $1.6 million

Senior Principal Research Fellow

Senior Principal Research Fellow

Teaching & student supervision

Courses and programs

Research degree supervision

Gallery