Dr Nicole Wittwer is a postdoctoral researcher in the Translational Oncology Laboratory at the Centre for Cancer Biology. She has a keen interest in the immune system and how we can modulate the immune system to fight back against cancer.
Dr Wittwer completed her PhD at the University of South Australia in the laboratory of Professor Angel Lopez, investigating the role of the stem cell marker CD123 in acute myeloid leukaemia. She then undertook a post-doctoral position at a highly successful Biotechnology company, Bionomics Ltd. As a member of the Oncology team, she worked on drug discovery and development programs and contributed to the identification and development of pharmacodynamic biomarkers directly in support of a phase I clinical ... Read more
About me
Dr Nicole Wittwer is a postdoctoral researcher in the Translational Oncology Laboratory at the Centre for Cancer Biology. She has a keen interest in the immune system and how we can modulate the immune system to fight back against cancer.
Dr Wittwer completed her PhD at the University of South Australia in the laboratory of Professor Angel Lopez, investigating the role of the stem cell marker CD123 in acute myeloid leukaemia. She then undertook a post-doctoral position at a highly successful Biotechnology company, Bionomics Ltd. As a member of the Oncology team, she worked on drug discovery and development programs and contributed to the identification and development of pharmacodynamic biomarkers directly in support of a phase I clinical trial in metastatic colorectal cancer.
Dr Wittwer is now based in the Translational Oncology Laboratory headed by Professor Michael Brown. The Translational Oncology Laboratory aims to develop new approaches to modulate the body’s immune system to more effectively target cancer cells and to translate these research discoveries into the clinic. Her research focuses on understanding how cancer cells override our immune defences and using this knowledge to develop therapeutic approaches to overcome immune resistance and sensitise cancer cells to therapy. Recent projects have focused on combining antibody drug conjugates with immunotherapy in breast and colon cancer in collaboration with Bristol Myers Squibb and the development of Chimeric Antigen Receptor (CAR) T-cells targeting a novel antigen in pancreatic cancer.
About me
Doctor of Philosophy University of South Australia
Bachelor of Laboratory Medicine with Honours University of South Australia
Research
Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus
Open access indicates that an output is open access.
Year | Output |
---|---|
2024 |
Open access
5
|
2023 |
Open access
8
9
|
2023 |
Open access
12
13
|
2022 |
Open access
54
50
|
2022 |
Open access
22
19
4
|
2022 |
Open access
1
|
2020 |
7
8
|
2017 |
Open access
26
25
1
|
External engagement & recognition
Organisation | Country |
---|---|
Flinders Medical Centre | AUSTRALIA |
Flinders University | AUSTRALIA |
GPCR Therapeutics | KOREA, REPUBLIC OF (SOUTH) |
Murdoch Childrens Research Institute | AUSTRALIA |
Royal Adelaide Hospital | AUSTRALIA |
SA Pathology | AUSTRALIA |
South Australian Health and Medical and Research Institute (SAHMRI) | AUSTRALIA |
Sydney Children's Hospital | AUSTRALIA |
University of Adelaide | AUSTRALIA |
University of Melbourne | AUSTRALIA |
University of New South Wales | AUSTRALIA |
University of South Australia | AUSTRALIA |
Utrecht University Medical Center | NETHERLANDS |
External engagement & recognition
Engagement/recognition | Year |
---|---|
Invited Panellist, Career Panel, Student Association CommitteeSouth Australian Health and Medical Research Institute (SAHMRI) |
2017 |
Runner-up best Early Career Researcher presentationAustralasian Society for Immunology (SA/NT) Adelaide Immunology Retreat |
2015 |
Best PhD presentationAustralian Society of Medical Research South Australian Annual Scientific Meeting |
2014 |
Invited SpeakerMedical Scientists at the Australian Institute of Medical Scientists SA/NT Annual Scientific Meeting |
2014 |
Best PhD presentationAustralian Society of Medical Research South Australian Annual Scientific Meeting |
2013 |
Best PhD presentationAustralasian Society for Immunology (SA/NT) Adelaide Immunology Retreat |
2012 |
Best Poster PrizeAustralasian Society of Immunology Annual Scientific Meeting |
2012 |
Member, Organising CommitteeAdelaide Immunology Retreat, Australasian Society for Immunology |
2012 |
Session chairAustralasian Society for Immunology (SA/NT) Adelaide Immunology Retreat |
2012 |
Teaching & student supervision
Supervisions from 2010 shown
Thesis title | Student status |
---|---|
Investigation of radiosensitization mechanisms using gold and aluminium nanoparticles under clinical beam radiation in the 4T1 mouse model of breast cancer | Current |