Dr Permal Deo has a background in Molecular Biology with a focus on advanced glycation endproducts (AGEs), and food safety. His Masters was obtained from The University of Queensland, Australia where his research focused on food mycotoxins. He graduated with a PhD from Queen’s University-Belfast, UK, where he researched on the role of advanced glycation endproducts on AGE-receptors, NF-kB, and pro-inflammatory cytokines. He joined the University of South Australia in 2010, after having worked at The University of the South Pacific, Fiji Islands. He is also a Visiting Scientist at CSIRO focusing on the molecular mechanism linking diabetes and Alzheimer’s disease.
Dr Deo’s research focuses on AGE-induced receptors... Read more
About me
Dr Permal Deo has a background in Molecular Biology with a focus on advanced glycation endproducts (AGEs), and food safety. His Masters was obtained from The University of Queensland, Australia where his research focused on food mycotoxins. He graduated with a PhD from Queen’s University-Belfast, UK, where he researched on the role of advanced glycation endproducts on AGE-receptors, NF-kB, and pro-inflammatory cytokines. He joined the University of South Australia in 2010, after having worked at The University of the South Pacific, Fiji Islands. He is also a Visiting Scientist at CSIRO focusing on the molecular mechanism linking diabetes and Alzheimer’s disease.
Dr Deo’s research focuses on AGE-induced receptors (RAGE), and activation of downstream signalling mechanisms including MAP kinase and NF-kB pathways. The impact of AGE on cell cytotoxicity, DNA –damage, and on Telomere dynamics are also explored. His research examines the role of natural products on AGE-induced signaling cascade as an alternative therapeutic approach. The role of these products with high antioxidant activities and/or their potential anti-inflammatory activities enables better insight on the mechanism in preventing or delaying the onset of chronic diseases. One of his interests is to study the role and functions of Australian Medicinal and Native Food plants in these signaling cascades.
From food safety perspective, his research focuses on antimicrobial properties of plant based novel peptides. The research also examines microbial analysis using molecular techniques of food and environmental samples.
About me
Professional Member of Australian Institute of Food Science and Technology (MAIFST)
Member of Australian Society of Microbiology (MASM)
Member of International Maillard Reaction Society.
About me
Doctor of Philosophy The Queen's University of Belfast
Master of Applied Science The University of Queensland
Graduate Certificate in Tertiary Teaching The University of the South Pacific
Bachelor of Science The University of the South Pacific
Advanced glycation endproducts - I am interested in understanding the mechanism linking diabetes and Alzheimer's disease. Receptor for Advanced Glycation Endproducts (RAGE), a multiligand member of the immunoglobulin superfamily of cell surface receptor for AGEs and amyloid-beta peptides. Current focus examines the molecular mechanism linking diabetes and Alzheimer's disease. The role of natural products as an alternative therapeutic approach is also investigated.
Research collaboration: this work is done in collaboration with Prof. Michael Fenech, CSIRO, Dr Susan Semple, UniSA, Dr Michael Netzel, The University of Queensland and Nutrafruit, Qld.
Food Safety and Quality – with ever increasing incidences of foodborne disease,... Read more
Research
Excludes commercial-in-confidence projects.
Improving safety of vegetable produce through on‐farm sanitation, using Electrolysed Oxidising (EO) Water - VG15068, Hort Innovation, 01/06/2017 - 31/05/2020
Provision of advanced-glycation endproducts (AGE) analysis in biological and food samples for SICS studies, Singapore Institute for Clinical Sciences, Biomedical Sciences Institutes, 15/06/2017 - 21/12/2018
Research
Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID, ResearcherID or Scopus
Open access indicates that an output is open access.
| Year | Output |
|---|---|
| 2024 |
Open access
|
| 2024 |
Open access
4
|
| 2024 |
Open access
|
| 2023 |
Open access
2
1
|
| 2023 |
Open access
4
3
341
|
| 2023 |
Open access
1
|
| 2023 |
Open access
4
4
282
|
| 2023 |
Open access
2
|
| 2023 |
Open access
8
7
3
|
| 2023 |
Open access
1
|
| 2023 |
Open access
1
140
|
| 2022 |
Open access
93
|
| 2022 |
4
4
1
|
| 2022 |
Open access
5
5
2
|
| 2022 |
Open access
6
5
1
|
| 2022 |
Open access
15
14
8
|
| 2022 |
Open access
2
2
2
|
| 2022 |
Open access
3
3
1
|
| 2022 |
Open access
9
6
603
|
| 2022 |
Open access
4
3
1
|
| 2021 |
Open access
10
11
|
| 2021 |
11
11
1
|
| 2021 |
Open access
15
11
4
|
| 2021 |
Open access
10
10
|
| 2021 |
Open access
29
26
1
|
| 2021 |
Open access
4
4
13
|
| 2021 |
1
1
|
| 2021 |
Open access
7
6
1
|
| 2021 |
Open access
16
13
|
| 2021 |
Open access
91
88
1494
|
| 2021 |
Open access
2
2
|
| 2020 |
Open access
30
26
|
| 2020 |
17
14
7
|
| 2020 |
Open access
16
14
11
|
| 2020 |
Open access
12
12
25
|
| 2020 |
16
16
1
|
| 2020 |
Open access
9
9
5
|
| 2020 |
5
5
1
|
| 2020 |
15
11
|
| 2020 |
Open access
22
19
249
|
| 2020 |
Open access
4
2
|
| 2019 |
34
23
237
|
| 2019 |
Open access
19
18
2
|
| 2019 |
Open access
27
25
1
|
| 2019 |
Open access
51
46
30
|
| 2019 |
Open access
9
7
|
| 2018 |
Open access
41
36
|
| 2017 |
Open access
20
20
2
|
| 2017 |
Open access
28
22
2
|
| 2016 |
Open access
31
27
5
|
| 2016 |
Open access
18
18
1
|
| 2016 |
Open access
13
12
|
| 2009 |
24
21
|
Research
Advanced glycation endproducts - I am interested in understanding the mechanism linking diabetes and Alzheimer's disease. Receptor for Advanced Glycation Endproducts (RAGE), a multiligand member of the immunoglobulin superfamily of cell surface receptor for AGEs and amyloid-beta peptides. Current focus examines the molecular mechanism linking diabetes and Alzheimer's disease. The role of natural products as an alternative therapeutic approach is also investigated.
Research collaboration: this work is done in collaboration with Prof. Michael Fenech, CSIRO, Dr Susan Semple, UniSA, Dr Michael Netzel, The University of Queensland and Nutrafruit, Qld.
Food Safety and Quality – with ever increasing incidences of foodborne disease, hence continuous identification of novel peptides with antimicrobial properties. In addition, in food processing, strict monitoring process and new sanitizers are explored to reduce the microbial levels reducing the risk of foodborne outbreak. Current research in this area focuses on: (1) use of natural products as antimicrobial inhibitors in cook-chill and ready-to-eat products: (2) assessment of new food sanitizers in reducing microbial contamination in seafood, minimally processed salads and meat; and (3) monitoring and evaluation of critical control and quality control point in food processing
Research collaboration: this work is done in collaboration with Prof. D. Trott, University of Adelaide, ECAS4 Pty Ltd, and food industries.
External engagement & recognition
| Organisation | Country |
|---|---|
| Baker Heart and Diabetes Institute | AUSTRALIA |
| Chuulangun Aboriginal Corporation | AUSTRALIA |
| CNR Institute of Clinical Physiology | ITALY |
| CSIRO Australia (Commonwealth Scientific Industrial Research organisation) | AUSTRALIA |
| Deakin University | AUSTRALIA |
| Dr Barry Lloyd Pty. Ltd. | AUSTRALIA |
| Ecas4 Australia | AUSTRALIA |
| Ecas4 Australia Pty Ltd | AUSTRALIA |
| Ecas4 Pty Ltd | AUSTRALIA |
| Faculty of Veterinary Medicine | IRAN |
| Fiji National University | FIJI |
| Flinders University | AUSTRALIA |
| Gyeongsang National University | KOREA, REPUBLIC OF (SOUTH) |
| Islamic Azad University | IRAN |
| Medical University of Vienna | AUSTRIA |
| Monash University | AUSTRALIA |
| Murdoch University | AUSTRALIA |
| Ospedale Policlinico San Martino | ARGENTINA |
| Prince Sattam Bin Abdulaziz University | SAUDI ARABIA |
| Queen's University Belfast | UNITED KINGDOM |
| Sabzevar University of Medical Sciences | IRAN |
| San Raffaele University | ITALY |
| San Raffaele University of Rome | ITALY |
| South Australian Research and Development Institute (SARDI) | AUSTRALIA |
| Tufts University | UNITED STATES |
| University Of A Coruna | SPAIN |
| University of Adelaide | AUSTRALIA |
| University of California | UNITED STATES |
| University of Copenhagen | DENMARK |
| University of Queensland | AUSTRALIA |
| University of South Australia | AUSTRALIA |
| University of the Sunshine Coast | AUSTRALIA |
| University of Vienna | AUSTRIA |
| University of Wuerzburg | GERMANY |
| Vrije University Brussel | BELGIUM |
External engagement & recognition
| Engagement/recognition | Year |
|---|---|
Professional MemberAustralian Institute of Food Science and Technology (AIFST) |
2018 |
Professional MemberAustralian Institute of Food Science and Technology (AIFST) |
2017 |
Food microbiology ,Food processing,Food Regulations,Functional Food, neutraceuticals
Teaching & student supervision
Teaching & student supervision
Supervisions from 2010 shown
| Thesis title | Student status |
|---|---|
| Advanced glycation end product induced genotoxicity and receptor expression in human cells | Completed |
| Methylglyoxal induces chromosomal instability under normal and folic acid deficient conditions | Completed |
| Screening for South Australian anti-Batrachochytrium dendrobatidis (Bd) probiotic candidates | Completed |
| The role of fatty acids on dicarbonyl- induced protein glycation, receptor expression and inflammatory biomarkers | Completed |
