Dr Preethi Eldi

Senior Research Fellow UniSA Clinical & Health Sciences

City West Campus (HB6-18)
tel +61 8 830 21440

email Preethi.Eldi@unisa.edu.au

Available for media comment
Research Degree Supervisor

Research

Research focus

Biological Sciences
Immunology
Biochemistry and Cell Biology
Pharmacology and Pharmaceutical Sciences
Medical and Health Sciences

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Journal Articles

Year	Output
2024	Khetan, R, Eldi, P, Lokman, NA, Ricciardelli, C, Oehler, MK, Blencowe, A, Garg, S, Pillman, K & Albrecht, H 2024, 'Unveiling G-protein coupled receptors as potential targets for ovarian cancer nanomedicines: from RNA sequencing data analysis to in vitro validation', Journal of Ovarian Research, vol. 17, article no. 156, pp. 1-13. Open access
2022	Eldi, P, Cooper, TH, Prow, NA, Liu, L, Heinemann, GK, Zhang, VJ, Trinidad, AD, Guzman-Genuino, RM, Wulff, P, Hobbs, LM, Diener, KR & Hayball, JD 2022, 'The vaccinia-based Sementis Copenhagen Vector coronavirus disease 2019 vaccine induces broad and durable cellular and humoral immune responses', Immunology and Cell Biology, vol. 100, no. 4, pp. 250-266. Open access 2 2 6
2021	Yu, M, Teo, T, Yang, Y, Li, M, Long, Y, Philip, S, Noll, B, Heinemann, GK, Diab, S, Eldi, P, Mekonnen, L, Anshabo, AT, Rahaman, MH, Milne, R, Hayball, JD & Wang, S 2021, 'Potent and orally bioavailable CDK8 inhibitors: design, synthesis, structure-activity relationship analysis and biological evaluation', European Journal of Medicinal Chemistry, vol. 214, pp. 1-22. Open access 12 11 1
2020	Day, J, Otto, S, Cash, K, Eldi, P, Hissaria, P, Proudman, S, Limaye, V & Hayball, JD 2020, 'Aberrant Expression of High Mobility Group Box Protein 1 in the Idiopathic Inflammatory Myopathies', Frontiers in Cell and Developmental Biology, vol. 8, article no. 226, pp. 1-11. Open access 12 13 1
2020	Le, TT, Fok, JS, Vareeckal-Joseph, S, Eldi, P, Chataway, T, Smith, W & Hissaria, P 2020, 'Transplant induced food sensitization without allergy-mechanisms of tolerance', Journal of Allergy and Clinical Immunology, vol. 8, no. 5, pp.1757-1760. 3 2 3
2020	Prow, NA, Liu, L, McCarthy, MK, Walters, K, Kalkeri, R, Geiger, J, Koide, F, Cooper, TH, Eldi, P, Nakayama, E, Diener, KR, Howley, PM, Hayball, JD, Morrison, TE & Suhrbier, A 2020, 'The vaccinia virus based Sementis Copenhagen Vector vaccine against Zika and chikungunya is immunogenic in non-human primates', Vaccines, vol. 5, no. 1, article no. 44, pp. 1-10. Open access 17 13 6
2019	Eldi, P, Chaudhri, G, Nutt, SL, Newsome, TP & Karupiah, G 2019, 'Viral replicative capacity, antigen availability via hematogenous spread, and high T FH:T FR ratios drive induction of potent neutralizing antibody responses', Journal of Virology, vol. 93, no. 6, article no. e01795-18. Open access 5 5 1
2019	Eldi, P, Cooper, T, Ward, M & Hayball, JD 2019, 'How emerging vaccine technologies are pushing disease prevention boundaries', International Pharmacy Journal, vol. 37, no. 1, pp. 16-19.
2019	Guzman-Genuino, RM, Eldi, P, Garcia-Valtanen, P, Hayball, JD & Diener, KR 2019, 'Uterine B cells exhibit regulatory properties during the peri-implantation stage of murine pregnancy', Frontiers in Immunology, vol. 10, article no. 2899, pp. 1-12. Open access 19 17 4
2018	Prow, NA, Liu, L, Nakayama, E, Cooper, TH, Yan, K, Eldi, P, Hazlewood, JE, Tang, B, Le, TT, Setoh, YX, Khromykh, AA, Hobson-Peters, J, Diener, KR, Howley, PM, Hayball, JD & Suhrbier, A 2018, 'A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses', Nature Communications, vol. 9, article no. 1230, pp. 1-12. Open access 63 61 82
2018	Zhang, W, Song, Y, Eldi, P, Guo, X, Hayball, JD, Garg, S & Albrecht, H 2018, 'Targeting prostate cancer cells with hybrid elastin-like polypeptide/liposome nanoparticles', International Journal of Nanomedicine, vol. 13, pp. 293-305. Open access 42 31 5
2017	Eldi, P, Cooper, TH, Liu, L, Prow, NA, Diener, KR, Howley, PM, Suhrbier, A & Hayball, JD 2017, 'Production of a Chikungunya vaccine using a CHO Cell and attenuated viral-based platform technology', Molecular Therapy, vol. 25, no. 10. pp. 2332-2344. Open access 17 17 10
2017	Liu, L, Cooper, T, Eldi, P, Garcia-Valtanen, P, Diener, KR, Howley, PM & Hayball, JD 2017, 'Transient dominant host-range selection using Chinese hamster ovary cells to generate marker-free recombinant viral vectors from vaccinia virus', Biotechniques: The Journal of Laboratory Technology for Bioresearch, vol. 62, no. 4, pp. 183-187. Open access 4 4 1
2017	Wijesundara, DK, Yu, W, Quah, BJ, Eldi, P, Hayball, JD, Diener, KR, Voskoboinik, I, Gowans, EJ & Grubor-Bauk, B 2017, 'Cytolytic DNA vaccine encoding lytic perforin augments the maturation of - and antigen presentation by - dendritic cells in a time-dependent manner', Scientific Reports, vol. 7, no. 1, article no. 8530, pp. 1-8. Open access 7 8 1
2016	Tao, B, Bernardo, K, Eldi, P, Chegeni, N, Wiese, M, Colella, A, Kral, A, Hayball, J, Smith, W, Forsyth, K & Chataway, T 2016, 'Extended boiling of peanut progressively reduces IgE allergenicity while retaining T cell reactivity', Clinical and Experimental Allergy, vol. 46, no. 11, pp. 1004-1014. 40 38 45
2016	Zhang, W, Garg, S, Eldi, P, Zhou, FH-h, Johnson, IR, Brooks, DA, Lam, F, Rychkov, G, Hayball, JD & Albrecht, H 2016, 'Targeting prostate cancer cells with genetically engineered polypeptide-based micelles displaying gastrin-releasing peptide', International Journal of Pharmaceutics, vol. 513, pp.270-279. 27 25 4
2015	Chaudhri, G, Tahiliani, V, Eldi, P & Karupiah, G 2015, 'Vaccine-induced protection against orthopoxvirus infection is mediated through the combined functions of CD4 T cell-dependent antibody and CD8 T cell responses', Journal of Virology, vol. 89, no. 3, pp. 1889-1899. Open access 14 12 8
2015	Sakala, IG, Chaudhri, G, Eldi, P, Buller, RM & Karupiah, G 2015, 'Deficiency in Th2 cytokine responses exacerbate orthopoxvirus infection', PLoS One, vol. 10, no. 3, article no. e0118685, pp. 1-21. Open access 7 7 2
2014	Andoniou, CE, Sutton, VR, Wikstrom, ME, Fleming, P, Thia, KY, Matthews, AY, Kaiserman, D, Schuster, IS, Coudert, JD, Eldi, P, Chaudhri, G, Karupiah, G, Bird, P I, Trapani, JA & Degli-Esposti, MA 2014, 'A natural genetic variant of granzyme B confers lethality to a common viral infection', PLoS Pathogens, vol. 10, no. 12, article no. e1004526, pp. 1-13. Open access 16 14 4
2013	Tahiliani, V, Chaudhri, G, Eldi, P & Karupiah, G 2013, 'The orchestrated functions of innate leukocytes and T cell subsets contribute to humoral immunity, virus control, and recovery from secondary poxvirus challenge', Journal of Virology. Open access 9 9
2009	Eldi, P & Rietze, R 2009, 'Flow cytometric characterization of neural precursor cells and their progeny'. 3
2009	Lee, S-H, Eldi, P, Cho, S-Y & Rangasamy, D 2009, 'Control of chicken CR1 retrotransposons is independent of Dicer-mediated RNA interference pathway', BMC Biology, vol. 7, article no. 53, pp. 1-14. Open access 15 13

Research

Patents

Details	Registry	Status
Attenuated poxvirus vector based vaccine for protection against covid-19 Prow, Natalie; Howley, Paul; Cooper, Tamara; Hayball, John; Diener, Kerrilyn R; Liu, Liang; Eldi, Preethi	US	Filed

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Australian National University	AUSTRALIA
Flinders University	AUSTRALIA
Hanyang University	KOREA, REPUBLIC OF (SOUTH)
John Curtin School of Medical Research	AUSTRALIA
Monash University	AUSTRALIA
Peter MacCallum Cancer Centre	AUSTRALIA
QIMR Berghofer Medical Research Institute	AUSTRALIA
Queensland Institute of Medical Research	AUSTRALIA
Royal Adelaide Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
Saint Louis University	UNITED STATES
Sementis	AUSTRALIA
Shandong University	CHINA
South Australian Health and Medical and Research Institute (SAHMRI)	AUSTRALIA
Southern Research Institute	UNITED STATES
University of Adelaide	AUSTRALIA
University of Colorado Denver	UNITED STATES
University of Melbourne	AUSTRALIA
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Sydney	AUSTRALIA
University of Western Australia	AUSTRALIA
Walter and Eliza Hall Institute of Medical Research	AUSTRALIA

External engagement & recognition

Engagement/recognition	Year
Invited speaker, Adelaide BioMed Research mini reviews Adelaide BioMed City, Health Innovation and Translation District	2021
Molecular Biosciences Seminar series Flinders Health and Medical Research Institute	2021
Invited Panel Member, Innovations in vaccines to counter emerging global health threats Pharmaceutical Science World Congress 2020	2020
Treasurer, 8th Australian and New Zealand Society for Immunology Annual Meeting 2019 Australian and New Zealand Society for Immunology	2019
Best Presentation from Early Career Researcher Adelaide Immunology Retreat, Australian and New Zealand Society for Immunology (ASI)	2016
Invited Speaker, BHI Research Seminars Bazil Hetzel Insitute for Translational Health Research	2016
Invited talk Australian Society of Clinical Immunology and Allergy Branch meeting	2016
Organising Committee Member, Adelaide Immunology Retreat 2016 Australian and New Zealand Society for Immunology	2016
Best Early Career Researcher presentation Australasian Society for Immunology (SA/NT) Adelaide Immunology Retreat	2015
Professional Member American Association for the Advancement of Science	2015
Professional Member Australian and New Zealand Society for Immunology	2014

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
Assessment of almond -specific antibody levels in participants from the Almond Weight Loss Study	Current
Preclinical evaluation of passive and active immunotherapies for melanoma	Current
Targeting ovarian cancer with nanoparticle drug carriers using G protein-coupled receptors as molecular entry sites	Current
Characterisation of immune-mediated necrotising myopathy	Completed
Elucidating the role of regulatory B cells in early pregnancy	Completed
Evaluation of antigen-specific immune responses elicited by single and multiple pathogen vaccines designed using a vaccinia virus-based vector system	Completed
Understanding a novel replication-deficient poxviral-based vector platform	Completed

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Dr Preethi Eldi

About me

About me

UniSA Clinical & Health Sciences

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Journal Articles

Patents

External engagement & recognition

Collaborations

Collaborations

External engagement & recognition

Invited speaker, Adelaide BioMed Research mini reviews

Molecular Biosciences Seminar series

Invited Panel Member, Innovations in vaccines to counter emerging global health threats

Treasurer, 8th Australian and New Zealand Society for Immunology Annual Meeting 2019

Best Presentation from Early Career Researcher

Invited Speaker, BHI Research Seminars

Invited talk

Organising Committee Member, Adelaide Immunology Retreat 2016

Best Early Career Researcher presentation

Professional Member

Professional Member

Teaching & student supervision

Courses and programs

Courses I teach

Research degree supervision

Gallery