Dr Rob Brooks

Casual teaching activities UniSA Clinical & Health Sciences

City West Campus ()
tel +61 8 830 22397

email Rob.Brooks@unisa.edu.au

Research Degree Supervisor

Research

Research focus

Biochemistry and Cell Biology
Other Chemical Sciences
Chemical Engineering
Clinical Sciences
Immunology

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Chapters

Year	Output
2012	Brooks, D, Bader, CA, Ng, Y, Brooks, RD, Borlace, G & Shandala, T 2012, 'At the intersection of the pathways for exocytosis and autophagy', in R Weigert (ed.), Crosstalk and integration of membrane trafficking pathways, InTech, Croatia, ch. 5, pp. 109-136. Open access
2012	Shandala, T, R Kakavanos-Plew, Ng, Y, Bader, CA, Sorvina, A, Parkinson-Lawrence, E, Brooks, RD, Borlace, G, Prodoehl, M & Brooks, D 2012, 'Molecular machinery regulating exocytosis', in R Weigert (ed.), Crosstalk and integration of membrane trafficking pathways, InTech, Croatia, ch. 4, pp. 61-108. Open access

Journal Articles

Year	Output
2024	Bates, M, Mullen, D, Lee, E, Costigan, D, Brooks, RD, Brooks, DA, Logan, JM, Martini, C & O'Leary, JJ and 13 other authors 2024, 'P53 and TLR4 expression are prognostic markers informing progression free survival of advanced stage high grade serous ovarian cancer', Pathology Research and Practice, vol. 253, article no. 155020, pp. 1-8. Open access 1 1 1
2024	Coward-Smith, M, Liong, S, Oseghale, O, Erlich, JR, Miles, MA, Liong, F, Brassington, K, Bozinovski, S, Vlahos, R, Brooks, RD, Brooks, DA, O'Leary, JJ & Selemidis, S 2024, 'Low dose aspirin prevents endothelial dysfunction in the aorta and foetal loss in pregnant mice infected with influenza A virus', Frontiers in Immunology, vol. 15, pp. 1-11. Open access 3 3 146
2024	Logan, JM, Martini, C, Sorvina, A, Johnson, IR, Brooks, RD, Caruso, MC, Huzzell, C, Moore, CR, Karageorgos, L, Butler, LM, Tewari, P, Prabhakaran, S, Hickey, SM, Klebe, S, Samaratunga, H, Delahunt, B, Moretti, K, O'Leary, JJ, Brooks, DA & Ung, BS 2024, 'Reinterpretation of prostate cancer pathology by Appl1, Sortilin and Syndecan-1 biomarkers', Scientific Data, vol. 11, article no. 852, pp. 1-10. Open access 1
2024	Martini, C, Logan, JM, Sorvina, A, Prabhakaran, S, Ung, BS, Johnson, IR, Hickey, SM, Brooks, RD, Caruso, MC, Klebe, S, Karageorgos, L, O'Leary, JJ, Delahunt, B, Samaratunga, H & Brooks, DA 2024, 'Distinct patterns of biomarker expression for atypical intraductal proliferations in prostate cancer', Virchows Archiv, vol. 485, pp. 723-728. Open access 1 2
2024	Miles, MA, Liong, S, Liong, F, Trollope, GS, Wang, H, Brooks, RD, Bozinovski, S, O'Leary, JJ, Brooks, DA & Selemidis, S 2024, 'TLR7 promotes acute inflammatory-driven lung dysfunction in influenza-infected mice but prevents late airway hyperresponsiveness', International Journal of Molecular Sciences, vol. 25, no. 24, article no. 13699, pp. 1-20. Open access
2024	Nturubika, BD, Guardia, CM, Gershlick, DC, Logan, JM, Martino, C, Heatlie, JK, Lazniewska, J, Moore, C, Lam, GT, Li, KL, Ung, BS-Y, Brooks, RD, Hickey, SM, Bert, AG, Gregory, PA, Butler, LM, O'Leary, JJ, Brooks, DA & Johnson, IRD 2024, 'Altered expression of vesicular trafficking machinery in prostate cancer affects lysosomal dynamics and provides insight into the underlying biology and disease progression', British Journal of Cancer, vol. 131, no. 8, pp. 1263-1278. Open access 2 2
2024	Nturubika, BD-D, Logan, J, Johnson, IRD, Moore, C, Li, KL, Tang, J, Lam, G, Parkinson-Lawrence, E, Williams, DB, Chakiris, J, Hindes, M, Brooks, RD, Gregory, P, Waugh, DJJ & Brooks, DA and 7other authors 2024, 'Components of the endosome-lysosome vesicular machinery as drivers of the metastatic cascade in prostate cancer', Cancers, vol. 17, no. 1, article no. 43, pp. 1-31. Open access 1
2024	Oseghale, O, Quinn, KM, Coward-Smith, M, Liong, F, Miles, MA, Brooks, RD, Vlahos, R, O'Leary, JJ, Brooks, DA, Liong, S & Selemidis, S 2024, 'Gestational influenza A virus infection elicits nonresolving vascular dysfunction and T-cell accumulation in the aorta of mice', American Journal of Physiology: Heart and Circulatory Physiology, vol. 327, no. 4, pp. H967-H977. 1
2024	Tang, J, Lam, GT, Brooks, RD, Miles, M, Useckaite, Z, Johnson, IR, Ung, BS, Martini, C, Karageorgos, L, Hickey, SM, Selemidis, S, Hopkins, AM, Rowland, A, Vather, R, O'Leary, JJ, Brooks, D., Caruso, MC & Logan, JM 2024, 'Exploring the role of sporadic BRAF and KRAS mutations during colorectal cancer pathogenesis: a spotlight on the contribution of the endosome-lysosome system', Cancer Letters, vol. 585, article no. 216639, pp. 1-9. Open access 4 3
2023	Bates, M, Mohamed, BM, Ward, MP, Kelly, TE, O'Connor, R, Malone, V, Brooks, R, Brooks, D, Selemidis, S, Martin, C, O'Toole, S & O'Leary, JJ 2023, 'Circulating tumour cells: the good, the bad and the ugly', Biochimica et Biophysica Acta: Reviews on Cancer, vol. 1878, no. 2, article no. 188863, pp. 1-12. Open access 22 18 7
2023	Ffrench, B, Kashdan, E, Huang, Y, Spillane, C, Brooks, D, Brooks, R & O'Leary, J and 15 other authors 2023, 'CTC-5: A novel digital pathology approach to characterise circulating tumour cell biodiversity', Heliyon, vol. 9, no. 1, article no. e13044, pp. 1-10. Open access 4 3 4
2023	Kelly, TE, Spillane, CL, Ward, MP, Hokamp, K, Huang, Y, Tewari, P, Martin, CM, Norris, LA, Mohamed, BM, Bates, M, Brooks, R, Selemidis, S, Brooks, DA, Kamran, W, Saadeh, FA, O'Toole, SA & O'Leary, JJ 2023, 'Plasminogen activator inhibitor 1 is associated with high-grade serous ovarian cancer metastasis and is reduced in patients who have received neoadjuvant chemotherapy', Frontiers in Cell and Developmental Biology, vol. 11 article no. 1150991, pp. 1-17. Open access 3 5 7
2023	Lam, GT, Martini, C, Brooks, T, Prabhakaran, S, Hopkins, AM, Ung, BS-Y, Tang, J, Caruso, MC, Brooks, RD, Johnson, IR, Sorvina, A, Hickey, SM, Karageorgos, L, Klebe, S, O'Leary, JJ, Brooks, DA & Logan, JM 2023, 'Insights into melanoma clinical practice: a perspective for future research', Cancers, vol. 15, no. 18, pp. 1-9. Open access 3 3
2023	Lam, GT, Sorvina, A, Martini, C, Prabhakaran, S, Ung, BS, Lazniewska, J, Moore, CR, Beck, AR, Johnson, IR, Caruso, MC, Hickey, SM, Brooks, RD, Karageorgos, L, Brooks, DA & Logan, JM and 6 other authors 2023, 'Altered endosomal-lysosomal biogenesis in melanoma', Neoplasia, vol. 43, article no. 100924, pp. 1-10. Open access 3 3 1
2023	Lazniewska, J, Li, KL, Johnson, IR, Sorvina, A, Logan, JM, Martini, C, Moore, C, Ung, BS, Karageorgos, L, Hickey, SM, Prabhakaran, S, Heatlie, JK, Brooks, RD, Huzzell, C, Warnock, N I, Moretti, P, Pitson, SM & Brooks, DA and 10 other authors 2023, 'Dynamic interplay between sortilin and syndecan-1 contributes to prostate cancer progression', Scientific Reports, vol. 13, no. 1, article no. 13489, pp. 1-18. Open access 10 9
2023	Logan, JM, Hopkins, AM, Martini, C, Sorvina, A, Huzzell, C, Johnson, IR, Hickey, SM, Ung, BS-Y, Lazniewska, J, Brooks, RD, Moore, CR, Caruso, MC, Karageorgos, L, Esterman, A, Moretti, K & Brooks, DA and 23 other authors 2023, 'Prediction of prostate cancer biochemical and clinical recurrence is improved by IHC-Assisted Grading using Appl1, Sortilin and Syndecan-1', Cancers, vol. 15, no. 12, pp. 1-12. Open access 9 8 122
2023	Martini, C, Logan, JM, Sorvina, A, Gordon, C, Beck, AR, Ung, BS, Caruso, MC, Moore, C, Johnson, IR, Li, KL, Karageorgos, L, Esterman, AJ, Huzzell, C, Brooks, RD, Lazniewska, J, Hickey, SM, Bader, CA, Parkinson-Lawrence, E, Prabhakaran, S, Moretti, KL & Brooks, DA and 28 other authors 2023, 'Aberrant protein expression of Appl1, Sortilin and Syndecan-1 during the biological progression of prostate cancer', Pathology, vol. 55, no. 1, pp. 40-51. Open access 16 16 81
2023	Miles, MA, Liong, S, Liong, F, Coward-Smith, M, Trollope, GS, Oseghale, O, Erlich, JR, Brooks, RD, Logan, JM, Hickey, S, Wang, H, Bozinovski, S, O'Leary, JJ, Brooks, DA & Selemidis, S 2023, 'TLR7 promotes chronic airway disease in RSV-infected mice', Frontiers in Immunology, vol. 14, pp. 1-21. Open access 4 4 9
2023	Mohamed, BM, Ward, MP, Bates, M, Spillane, CD, Kelly, T, Martin, C, Gallagher, M, Heffernan, S, Norris, L, Kennedy, J, Saadeh, FA, Gleeson, N, Brooks, DA, Brooks, RD, Selemidis, S, O Toole, S & O'Leary, JJ 2023, 'Ex vivo expansion of circulating tumour cells (CTCs)', Scientific Reports, vol. 13, no. 1, pp. 1-13. Open access 10 10 1
2023	Sorvina, A, Martini, C, Prabhakaran, S, Logan, JM, Ung, BS-Y, Moore, C, Johnson, IR, Lazniewska, J, Tewari, P, Malone, V, Brooks, RD, Hickey, SM, Caruso, MC, Klebe, S, Karageorgos, L, O'Leary, JJ, Delahunt, B, Samaratunga, H & Brooks, DA 2023, 'Appl1, Sortilin and Syndecan-1 immunohistochemistry on intraductal carcinoma of the prostate provides evidence of retrograde spread', Pathology, vol. 55, no. 6, pp. 792-799. Open access 8 8
2022	Erlich, JR, To, EE, Luong, R, Liong, F, Liong, S, Oseghale, O, Miles, MA, Bozinovski, S, Brooks, RD, Vlahos, R, Chan, S, O'Leary, JJ, Brooks, DA & Selemidis, S 2022, 'Glycolysis and the pentose phosphate pathway promote LPS-induced NOX2 oxidase- and IFN-β-dependent inflammation in macrophages', Antioxidants, vol. 11, no. 8, article no. 1488. Open access 25 25
2022	Hickey, SM, Ung, B, Bader, C, Brooks, R, Lazniewska, J, Johnson, IR, Sorvina, A, Logan, J, Martini, C, Moore, CR, Karageorgos, L, Sweetman, MJ & Brooks, DA 2022, 'Fluorescence microscopy-an outline of hardware, biological handling, and fluorophore considerations', Cells, vol. 11, no. 35, pp. 1-32. Open access 57 48 1
2022	Oseghale, O, Liong, S, Coward-Smith, M, To, EE, Erlich, JR, Luong, R, Liong, F, Miles, M, Norouzi, S, Martin, C, O'Toole, S, Brooks, RD, Bozinovski, S, Vlahos, R, O'Leary, JJ, Brooks, DA & Selemidis, S 2022, 'Influenza A virus elicits peri-vascular adipose tissue inflammation and vascular dysfunction of the aorta in pregnant mice', PLoS Pathogens, vol. 18, no. 8, pp. 1-21. Open access 7 7 4
2022	Oseghale, O, Vlahos, R, O'Leary, JJ, Brooks, RD, Brooks, DA, Liong, S & Selemidis, S 2022, 'Influenza Virus Infection during Pregnancy as a trigger of acute and chronic complications', Viruses, vol. 14, no. 12, article no. 2729, pp. 1-22. Open access 13 13 2
2022	To, EE, Erlich, JR, Liong, F, Liong, S, Luong, R, Oseghale, O, Miles, MA, Papagianis, PC, Quinn, KM, Bozinovski, S, Vlahos, R, Brooks, RD, O'Leary, JJ, Brooks, DA & Selemidis, S 2022, 'Therapeutic targeting of endosome and mitochondrial reactive oxygen species protects mice from influenza virus morbidity', Frontiers in Pharmacology, vol. 13, article no. 870156, pp. 1-12. Open access 5 5 2
2021	Gillam, TA, Caporale, C, Brooks, RD, Bader, CA, Sorvina, A, Werrett, M V, Wright, PJ, Morrison, JL, Massi, M, Brooks, DA, Zacchini, S, Hickey, SM, Stagni, S & Plush, SE 2021, 'Neutral Re(I) complex platform for live intracellular imaging', Inorganic Chemistry: Including Bioinorganic Chemistry, vol. 60, no. 14, pp. 10173-10185. 11 11 9
2021	Spillane, CD, Cooke, NM, Ward, MP, Kenny, D, Brooks, DA, Brooks, RD, Heatlie, JK & O'Leary, JJ and 18 other authors 2021, 'The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon', Translational Oncology, vol. 14, no. 12, article no. 101229, pp. 1-13. Open access 9 9
2021	Ward, MP, Kane, LE, Norris, LA, Mohamed, BM, Kelly, T, Bates, M, Clarke, A, Brady, N, Martin, CM, Brooks, RD, Brooks, DA, Selemidis, S, Hanniffy, S, Dixon, EP, O'Toole, SA & O'Leary, JJ 2021, 'Platelets, immune cells and the coagulation cascade; friend or foe of the circulating tumour cell?', Molecular Cancer, vol. 20, no. 59, pp. 1-17. Open access 91 88 13
2020	Bates, M, Spillane, CD, Gallagher, MF, McCann, A, Martin, C, Blackshields, G, Keegan, H, Gubbins, L, Brooks, R, Brooks, D, Selemidis, S, O'Toole, S & O'Leary, JJ 2020, 'The role of the MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer', PLoS One, vol. 15, no. 12, pp. 1-22. Open access 14 12 15
2020	Erlich, JR, To, EE, Liong, S, Brooks, R, Vlahos, R, O'Leary, JJ, Brooks, DA & Selemidis, S 2020, 'Targeting evolutionary conserved oxidative stress and immunometabolic pathways for the treatment of respiratory infectious diseases', Antioxidants and Redox Signaling, vol. 32, no. 13, pp. 993-1013. Open access 26 19 1
2020	Liong, S, Oseghale, O, To, EE, Brassington, K, Erlich, JR, Luong, R, Liong, F, Brooks, R, Martin, C, O'Toole, S, Vinh, A, O'Neill, LA, Bozinovski, S, Vlahos, R, Papagianis, PC, O'Leary, JJ, Brooks, DA & Selemidis, S 2020, 'Influenza A virus causes maternal and fetal pathology via innate and adaptive vascular inflammation in mice', Proceedings of the National Academy of Sciences of USA, vol. 117, no. 40, pp. 24964-24973. Open access 52 48 187
2020	To, EE, O'Leary, JJ, O'Neill, LA, Vlahos, R, Bozinovski, S, Porter, CJ, Brooks, RD, Brooks, DA & Selemidis, S 2020, 'Spatial properties of reactive oxygen species govern pathogen-specific immune system responses', Antioxidants and Redox Signaling, vol. 32, no. 13, pp. 982-992. Open access 20 19 3
2014	Bader, CA, Brooks, RD, Ng, YS, Sorvina, A, Werrett, M V, Wright, PJ, Anwer, AG, Brooks, DA, Stagni, S, Muzzioli, S, Silberstein, M, Skelton, BW, Goldys, EM, Plush, SE, Shandala, T & Massi, M 2014, 'Modulation of the organelle specificity in Re(i) tetrazolato complexes leads to labeling of lipid droplets', RSC Advances: An International Journal to Further the Chemical Sciences, vol. 4, no. 31, pp. 16345-16351. Open access 54 49
2014	Du, Z, Borlace, GN, Brooks, RD, Butler, RN, Brooks, DA & Plush, SE 2014, 'Synthesis and characterisation of folic acid based lanthanide ion probes', Inorganica Chimica Acta, vol. 410, pp. 11-19. 10 8
2014	Jenie, SA, Pace, S, Sciacca, B, Brooks, RD, Plush, SE & Voelcker, NH 2014, 'Lanthanide luminescence enhancements in porous silicon resonant microcavities', ACS Applied Materials and Interfaces, vol. 6, no. 15, pp. 12012-12021. 52 51
2013	Brooks, RD, Du, Z, Borlace, G, Brooks, D & Plush, S 2013, 'Synthesis and characterisation of first generation luminescent lanthanide complexes suitable for being adapted for uptake via the mannose receptor', Journal of Inorganic Chemistry, vol. 2013, pp. 1-8. Open access

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
BD Research Centre Ireland	IRELAND
BD Technologies and Innovation	UNITED STATES
Curtin University	AUSTRALIA
Dublin City University	IRELAND
Flinders Medical Centre	AUSTRALIA
Flinders University	AUSTRALIA
La Trobe University	AUSTRALIA
Macquarie University	AUSTRALIA
Malaghan Institute of Medical Research	NEW ZEALAND
Monash University	AUSTRALIA
National Institutes of Health	UNITED STATES
RMIT University	AUSTRALIA
Royal College of Surgeons in Ireland	IRELAND
St. James's Hospital	UNITED STATES
The Coombe Hospital	IRELAND
Trinity College Dublin	IRELAND
University College Dublin	IRELAND
University of Adelaide	AUSTRALIA
University of Bologna	ITALY
University of Cambridge	UNITED KINGDOM
University of Dublin	IRELAND
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Western Australia	AUSTRALIA
Xinxiang Medical University	CHINA

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
Development of monoclonal antibody targeted therapeutics for prostate cancer	Completed

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Dr Rob Brooks

About me

About me

UniSA Clinical & Health Sciences

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Chapters

Journal Articles

External engagement & recognition

Collaborations

Collaborations

Teaching & student supervision

Courses and programs

Courses I teach

Research degree supervision

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