Dr Ryan Murphy

Lecturer UniSA STEM

email Ryan.Murphy@unisa.edu.au

Research

Research focus

Biological Sciences
Mathematical Sciences
Biochemistry and Cell Biology
Engineering
Information and Computing Sciences

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID, ResearcherID or Scopus

Open access indicates that an output is open access.

Chapters

Year	Output
2024	Spoerri, L, Beaumont, KA, Anfosso, A, Murphy, RJ, Browning, AP, Gunasingh, G & Haass, NK 2024, 'Real-time cell cycle imaging in a 3D cell culture model of melanoma, quantitative analysis, optical clearing, and mathematical modeling', in Z Sumbalova Koledove (ed.), 3D Cell Culture: Methods and Protocols, Humana Press, US, ch. 19, pp. 291-310.

Journal Articles

Year	Output
2025	Buenzli, PR, Kuba, S, Murphy, RJ & Simpson, MJ 2025, 'Mechanical cell interactions on curved interfaces', Bulletin of Mathematical Biology, vol. 87, no. 2, article no. 29, pp. 1-40. Open access
2024	Murphy, RJ, Gunasingh, G, Haass, NK & Simpson, MJ 2024, 'Formation and growth of co-culture tumour spheroids: new compartment-based mathematical models and experiments', Bulletin of Mathematical Biology, vol. 86, no. 1, article no. 8, pp. 1-34. Open access 1
2024	Murphy, RJ, Maclaren, OJ & Simpson, MJ 2024, 'Implementing measurement error models with mechanistic mathematical models in a likelihood-based framework for estimation, identifiability analysis and prediction in the life sciences', Journal of the Royal Society Interface, vol. 21, no. 210, article no. 20230402, pp. 1-22. Open access 6
2024	Simpson, MJ, Murphy, RJ & Maclaren, OJ 2024, 'Modelling count data with partial differential equation models in biology', Journal of Theoretical Biology, vol. 580, article no. 111732, pp. 1-11. Open access 7
2023	Murphy, RJ, Gunasingh, G, Haass, NK & Simpson, MJ 2023, 'Growth and adaptation mechanisms of tumour spheroids with time-dependent oxygen availability', PLoS Computational Biology, vol. 19, no. 1, article no. e1010833, pp. 1-29. Open access 5
2023	Simpson, MJ, Walker, SA, Studerus, EN, McCue, SW, Murphy, RJ & Maclaren, OJ 2023, 'Profile likelihood-based parameter and predictive interval analysis guides model choice for ecological population dynamics', Mathematical Biosciences, vol. 355, article no. 108950, pp. 1-12. Open access 6
2022	Jolly, MK, Murphy, RJ, Bhatia, S, Whitfield, HJ, Redfern, A, Davis, MJ & Thompson, EW 2022, 'Measuring and modelling the epithelial- mesenchymal hybrid state in cancer: clinical implications', Cells, Tissues, Organs: in Vivo, in Vitro, vol. 211, no. 2, pp. 110-133. 27
2022	Klowss, JJ, Browning, AP, Murphy, RJ, Carr, EJ, Plank, MJ, Gunasingh, G, Haass, NK & Simpson, MJ 2022, 'A stochastic mathematical model of 4D tumour spheroids with real-time fluorescent cell cycle labelling', Journal of the Royal Society Interface, vol. 19, no. 189, article no. 20210903, pp. 1-11. Open access 14
2022	Murphy, RJ, Browning, AP, Gunasingh, G, Haass, NK & Simpson, MJ 2022, 'Designing and interpreting 4D tumour spheroid experiments', Communications Biology, vol. 5, no. 1, article no. 91, pp. 1-11. Open access 22
2022	Murphy, RJ, Maclaren, OJ, Calabrese, AR, Thomas, PB, Warne, DJ, Williams, ED & Simpson, MJ 2022, 'Computationally efficient framework for diagnosing, understanding and predicting biphasic population growth', Journal of the Royal Society Interface, vol. 19, no. 197, article no. 20220560, pp. 1-14. Open access 7
2021	Browning, AP, Sharp, JA, Murphy, RJ, Gunasingh, G, Lawson, B, Burrage, K, Haass, NK & Simpson, M 2021, 'Quantitative analysis of tumour spheroid structure', eLife, vol. 10, article no. e73020, pp. 1-25. Open access 39
2021	Murphy, R, Buenzli, P, Baker, RE & Simpson, M 2021, 'Travelling waves in a free boundary mechanobiological model of an epithelial tissue', Applied Mathematics Letters, vol. 111, article no. 106636, pp. 1-6. Open access 9
2021	Murphy, RJ, Buenzli, PR, Tambyah, TA, Thompson, EW, Hugo, HJ, Baker, RE & Simpson, MJ 2021, 'The role of mechanical interactions in EMT', Physical Biology, vol. 18, no. 4, article no. 046001, pp. 1-12. Open access 8
2021	Reye, G, Huang, X, Haupt, LM, Murphy, RJ, Northey, JJ, Thompson, EW, Momot, K I & Hugo, HJ 2021, 'Mechanical pressure driving proteoglycan expression in mammographic density: a self-perpetuating cycle?', Journal of Mammary Gland Biology and Neoplasia, vol. 216, no. 3, pp. 277-296. Open access 3
2020	Murphy, RJ, Buenzli, PR, Baker, RE & Simpson, MJ 2020, 'Mechanical cell competition in heterogeneous epithelial tissues', Bulletin of Mathematical Biology, vol. 82, no. 10, article no. 130, pp. 1-27. Open access 14
2020	Tambyah, TA, Murphy, RJ, Buenzli, PR & Simpson, MJ 2020, 'A free boundary mechanobiological model of epithelial tissues: a model of epithelial tissues', Proceedings of the Royal Society A: Mathematical Physical and Engineering Sciences, vol. 476, no. 2243, article no. 0528, pp. 1-18. 7
2019	Murphy, R, Buenzli, P, Baker, R & Simpson, M 2019, 'A one-dimensional individual-based mechanical model of cell movement in heterogeneous tissues and its coarse-grained approximation', Proceedings of the Royal Society A: Mathematical Physical and Engineering Sciences, vol. 475, no. 2227, article no. 20180838, pp. 1-17. Open access 20

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Centenary Institute	AUSTRALIA
Indian Institute of Science	INDIA
Queensland University of Technology	AUSTRALIA
University of Auckland	NEW ZEALAND
University of Canterbury	NEW ZEALAND
University of Melbourne	AUSTRALIA
University of Oxford	UNITED KINGDOM
University of Pennsylvania	UNITED STATES
University of Queensland	AUSTRALIA
University of Western Australia	AUSTRALIA

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Dr Ryan Murphy

About me

About me

UniSA STEM

About me

Professional Associations

Research

Research focus

Projects

Outputs

Chapters

Journal Articles

External engagement & recognition

Collaborations

Collaborations

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