Centre for Cancer Biology
I joined UniSA in 2014 as the Chair of Cancer Biology and a Research Professor of Cell Biology.
After completing a PhD from University of Adelaide and postdoctoral training at University of Queensland, I held research scientist/staff positions at CSIRO (Geelong), RIKEN (Tsukuba, Japan), and the Cancer Institute (Tokyo, Japan), before returning to Adelaide to start a research program at the Hanson Centre for Cancer Research at IMVS (which later became SA Pathology). In 2009, with Angel Lopez, I co-founded the Centre for Cancer Biology (CCB), which I co-directed for around 11 years.
I am passionate about science and discovery research! I have been trained as a biochemist, molecular biologist and cell biologist. My current research... Read more
About me
I joined UniSA in 2014 as the Chair of Cancer Biology and a Research Professor of Cell Biology.
After completing a PhD from University of Adelaide and postdoctoral training at University of Queensland, I held research scientist/staff positions at CSIRO (Geelong), RIKEN (Tsukuba, Japan), and the Cancer Institute (Tokyo, Japan), before returning to Adelaide to start a research program at the Hanson Centre for Cancer Research at IMVS (which later became SA Pathology). In 2009, with Angel Lopez, I co-founded the Centre for Cancer Biology (CCB), which I co-directed for around 11 years.
I am passionate about science and discovery research! I have been trained as a biochemist, molecular biologist and cell biologist. My current research interests are in molecular mechanisms of disease, including cancer. Our research has resulted in fundamental discoveries in two key fields of intense contemporary interest: cell death and ubiquitin-dependent protein modification. Some of our key discoveries include the Nedd genes, e.g. identification of one of the first mammalian caspases (Nedd2/caspase-2); a novel family of ubiquitin ligases (the Nedd4 family); and the ubiquitin-like protein Nedd8 that is involved in a protein-modification process, now widely known as Neddylation. We also discovered and characterised a large part of the Drosophila cell death machinery, identified Ndfip1 and Ndfip2 as adaptors/regulators of ubiquitin ligases and characterised a previously unknown autophagy-dependent cell death program during development. Our work has resulted in groundbreaking contributions to the understanding of many human ailments including cancer, cardiovascular and kidney diseases.
I am a Fellow of the Australian Academy of Science (AAS) and the Australian Academy of Health and Medical Sciences (AAHMS). In 2018 I was appointed a Member of the Order of Australia (AM). My professional contributions have also been recognised through a Wellcome Trust (UK) Senior Fellowship in Medical Sciences, the ASBMB Amersham Biosciences Award, the Ranbaxy Research Award, the Lemberg Medal of the ASBMB, the FAOBMB Research Excellence Award, the ANZSCDB President's Medal and the '2020 South Australian Scientist of the Year' award.
Our work has been published in over 280 articles, cited more than 53,500 times with a current H index of 99 (Google Scholar). Our research has also been presented in over 240 invited international and national talks and seminars. I have had the privilege of mentoring 30 postdoctoral scientists, 32 laboratory staff and 25 PhD students.
About me
Doctor of Biochemistry The University of Adelaide
Master of Science GB Pant University
Bachelor of Science Rohilkhand University
Cancer Biology
Cell Death
Ubiquitination
Disease models and mechanisms
Cellular and molecular biology
Research
Excludes commercial-in-confidence projects.
Regulation of autophagy dependent cell and tissue deletion, ARC - Discovery Projects, 01/01/2021 - 31/12/2023
Ubiquitination-regulated sodium homeostasis in kidney disease, NHMRC - Project Grant, 01/01/2019 - 31/12/2021
Deciphering the mechanisms of caspase-2-mediated suppression of aneuploidy and tumourigenesis, NHMRC - Project Grant, 01/01/2019 - 31/12/2021
Regulation of cell death, cell survival and ubiquitination in normal physiology and disease, NHMRC - Research Fellowship, 01/01/2016 - 31/12/2021
Using mouse models to decipher the function of caspase-2 in limiting aneuploidy tolerance and cancer, NHMRC - Project Grant, 01/01/2018 - 30/06/2021
Cell death by self-eating: understanding autophagy-dependent tissue removal, ARC - Discovery Projects, 13/01/2017 - 12/01/2020
Hormone dependent autophagy and growth signalling in developmental cell death, NHMRC - Project Grant, 01/01/2017 - 31/12/2019
Exploring the role of Arrcd4 in extracellular vesicle biogenesis and its implications in tissue homeostasis , NHMRC - Project Grant, 01/01/2017 - 31/12/2019
Nedd4-2: a new player in polycystic kidney disease, NHMRC - Project Grant, 01/01/2016 - 31/12/2018
Cancer Discovery Accelerator, Australian Cancer Research Foundation, 01/06/2016 - 31/07/2018
Deciphering the function of capcase-2 in DNA damage response and tumour suppression, NHMRC - Project Grant, 01/01/2014 - 31/12/2017
Post-translational control of cell fate decision, ARC - Discovery Projects, 01/01/2015 - 31/12/2017
Cancer Discovery Accelerator, Cancer Council SA - Beat Cancer, 08/06/2016 - 08/06/2017
A novel mechanism for regulating membrane proteins by ubiquitin ligases and their adaptors, NHMRC - Project Grant, 01/01/2014 - 31/12/2016
Understanding the role of capcase-2 in cellular stress response and ageing, NHMRC - Project Grant, 06/03/2014 - 31/12/2016
NHMRC Equip 2015 - SynergyHT fluorescence and UV/Vis 96-well plate reader for high throughput nucleic acid quantification via picogreen, NHMRC - Equipment Only Grants, 01/01/2016 - 31/12/2016
Autophagy and growth signalling in developmentally programmed cell death, NHMRC - Project Grant, 01/01/2014 - 31/12/2016
Deciphering the mechanisms of a caspase-mediated tumour suppressor pathway, Worldwide Cancer Research (formerly - Association for International Cancer Research), 01/06/2013 - 31/08/2016
NHMRC Equipment Grant 2014: Eppendorf Nexus Gradient PCR, NHMRC - Equipment Only Grants, 01/01/2015 - 31/12/2015
Physiological function of Nedd4-2 in regulating the epithelial sodium channel and cystic fibrosis transmembrane conductance regulator, NHMRC - Project Grant, 01/01/2014 - 31/12/2015
NHMRc Equipment Grant 2014: ChemiDoc MP system, NHMRC - Equipment Only Grants, 01/01/2015 - 31/12/2015
Regulation of cell death, cell survival and ubiquitination in normal physiology and disease, NHMRC - Research Fellowship, 01/01/2014 - 31/12/2015
Research
Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus
Open access indicates that an output is open access.
Year | Output |
---|---|
2021 |
Open access
15
12
15
|
2021 |
Open access
14
16
3
|
2019 |
Open access
372
327
18
|
2017 |
Open access
137
135
2
|
2014 |
Open access
243
804
22
|
Year | Output |
---|---|
2023 |
|
2021 |
Open access
9
|
2013 |
1
|
Year | Output |
---|---|
2023 |
|
2023 |
Open access
|
2023 |
Open access
6
1
1
|
2023 |
Open access
1
|
2023 |
9
|
2022 |
Open access
4
3
2
|
2022 |
Open access
11
8
4
|
2022 |
Open access
3
2
5
|
2022 |
Open access
3
2
7
|
2022 |
Open access
2
1
16
|
2021 |
9
8
18
|
2021 |
14
18
18
|
2021 |
Open access
6
5
26
|
2021 |
Open access
11
8
27
|
2021 |
1027
715
184
|
2021 |
Open access
390
296
183
|
2021 |
Open access
15
12
15
|
2021 |
Open access
16
13
5
|
2021 |
Open access
7
6
112
|
2021 |
Open access
14
16
3
|
2021 |
18
17
34
|
2021 |
6
5
2
|
2020 |
4
3
4
|
2020 |
Open access
13
12
5
|
2020 |
4
3
102
|
2020 |
Open access
2
2
2
|
2020 |
Open access
8
7
6
|
2020 |
1
1
5
|
2020 |
53
42
12
|
2019 |
145
124
7
|
2019 |
Open access
372
327
18
|
2019 |
Open access
3
5
5
|
2019 |
Open access
36
36
4
|
2019 |
Open access
2
2
6
|
2019 |
6
6
4
|
2019 |
Open access
30
24
5
|
2018 |
Open access
35
29
4
|
2018 |
Open access
118
110
14
|
2018 |
Open access
3232
2685
201
|
2018 |
Open access
11
9
3
|
2018 |
Open access
50
52
1
|
2018 |
Open access
36
35
16
|
2017 |
Open access
47
44
10
|
2017 |
Open access
137
135
2
|
2017 |
Open access
1045
963
67
|
2017 |
Open access
19
18
2
|
2017 |
Open access
7
6
2
|
2017 |
10
10
|
2016 |
14
15
5
|
2016 |
Open access
20
21
10
|
2016 |
Open access
8
8
|
2016 |
Open access
251
224
11
|
2016 |
Open access
4139
3604
360
|
2016 |
Open access
34
32
1
|
2016 |
Open access
28
26
10
|
2016 |
Open access
14
14
1
|
2016 |
Open access
21
19
|
2015 |
Open access
104
98
|
2015 |
1
6
|
2015 |
4
|
2015 |
10
|
2015 |
Open access
11
|
2015 |
Open access
2
1
|
2015 |
9
1
|
2015 |
137
136
2
|
2015 |
Open access
706
661
30
|
2015 |
Open access
932
864
112
|
2015 |
Open access
108
107
1
|
2015 |
Open access
32
30
1
|
2015 |
Open access
11
18
7
|
2015 |
Open access
32
30
11
|
2015 |
Open access
16
44
13
|
2014 |
Open access
14
14
2
|
2014 |
10
9
|
2014 |
2
|
2014 |
Open access
18
18
1
|
2014 |
Open access
29
28
4
|
2014 |
Open access
45
41
1
|
2014 |
Open access
243
804
22
|
2014 |
Open access
25
22
1
|
2013 |
Open access
57
56
|
2013 |
Open access
47
42
|
2013 |
Open access
166
144
3
|
2013 |
Open access
79
74
1
|
2013 |
Open access
57
53
16
|
2013 |
Open access
116
114
24
|
2013 |
Open access
208
196
6
|
2013 |
Open access
22
25
4
|
2012 |
Open access
58
52
|
2012 |
Open access
321
309
|
2012 |
Open access
82
81
|
2012 |
Open access
1972
1803
|
2012 |
Open access
35
30
|
2012 |
Open access
85
83
|
2012 |
Open access
2825
3054
|
2012 |
Open access
30
26
|
2012 |
Open access
63
55
|
2011 |
Open access
77
72
|
2011 |
Open access
18
18
|
2011 |
Open access
35
33
|
2011 |
Open access
12
10
|
2011 |
Open access
67
61
|
2010 |
Open access
53
49
|
2010 |
Open access
48
41
|
2010 |
Open access
18
20
|
2010 |
Open access
13
13
|
2010 |
Open access
34
33
|
2010 |
Open access
172
168
|
2009 |
Open access
300
285
|
2009 |
Open access
|
2009 |
Open access
137
128
|
2009 |
Open access
87
84
|
2009 |
Open access
79
73
|
2009 |
Open access
2288
2254
|
2009 |
14
11
|
2009 |
120
119
|
2009 |
Open access
47
42
|
2009 |
Open access
791
749
|
2008 |
Open access
25
24
|
2008 |
Open access
132
123
|
2008 |
29
28
|
2008 |
Open access
49
45
|
2008 |
Open access
113
104
|
2008 |
Open access
28
29
|
2008 |
Open access
160
144
|
2008 |
Open access
106
100
|
2008 |
13
14
|
2008 |
Open access
120
116
|
2008 |
24
23
|
Research
Cancer Biology
Cell Death
Ubiquitination
Disease models and mechanisms
Cellular and molecular biology
PROFESSIONAL RECOGNITION
Fellowships of the Learned Academies
Fellow of the Australian Academy of Science (FAA)
Fellow of the Australian Academy of Health and Medical Sciences (FAHMS)
International and National Fellowships
NHMRC Level 3 Investigator (Senior Principal Research Fellowship)
NHMRC Senior Principal Research Fellowship
NHMRC Principal Research Fellowship
Wellcome Trust (UK) Senior Fellowship in Medical Science
Florey Research Fellowship
Japanese Science and Technology Agency (STA) Fellowship
University of Queensland Postdoctoral Fellowship
Significant Awards and Prizes
Bradley Distinguished Professor
South Australian Scientist of the Year
Member of the Order of Australia
ANZSCDB President's Medal
FAOBMB Award for Research Excellence
ASBMB Lemberg Medal
Ranbaxy Science Foundation Award in Basic Medical Sciences
External engagement & recognition
Organisation | Country |
---|---|
Ain Shams University | EGYPT |
Australian National University | AUSTRALIA |
Baker Heart and Diabetes Institute | AUSTRALIA |
Baylor College of Medicine | UNITED STATES |
Boston University | UNITED STATES |
Candiolo Cancer Institute | ITALY |
Centre de Recherche des Cordeliers | FRANCE |
Centro de Investigaciones Biológicas | SPAIN |
Childrens Cancer Institute Australia for Medical Research | AUSTRALIA |
Cold Spring Harbor Laboratory | UNITED STATES |
CSIRO Australia (Commonwealth Scientific Industrial Research Organisation) | AUSTRALIA |
Deakin University | AUSTRALIA |
Duke University | UNITED STATES |
Emory University | UNITED STATES |
Federal University of Sao Carlos | BRAZIL |
Federico II University | ITALY |
Flinders Medical Centre | AUSTRALIA |
Florey Neuroscience Institute | AUSTRALIA |
Garvan Institute of Medical Research | AUSTRALIA |
Genentech | UNITED STATES |
Georgetown University | UNITED STATES |
Ghent University | BELGIUM |
Griffith University | AUSTRALIA |
Hanson Institute | AUSTRALIA |
Harry Perkins Institute of Medical Research | AUSTRALIA |
Harvard University | UNITED STATES |
Hebrew University | MEXICO |
Hong Kong Baptist University | HONG KONG |
Hudson Institute of Medical Research | AUSTRALIA |
Icahn School of Medicine at Mount Sinai | UNITED STATES |
Indian Council of Medical Research | INDIA |
Institute of Medical and Veterinary Science | AUSTRALIA |
Jilin University | CHINA |
Johannes Gutenberg University of Mainz | GERMANY |
Kanazawa University | JAPAN |
Kanazawa University Hospital | JAPAN |
Karolinska Institute | SWEDEN |
Keio University | JAPAN |
La Trobe University | AUSTRALIA |
Lausanne University Hospital | FRANCE |
Max Planck Institute of Experimental Medicine | GERMANY |
Mayo Clinic | UNITED STATES |
Medical University of Graz | AUSTRIA |
Medical University of Innsbruck | AUSTRIA |
Monash University | AUSTRALIA |
National Institute on Aging | UNITED STATES |
New York University | UNITED STATES |
Okayama University | JAPAN |
Osaka University | JAPAN |
Ozgene | AUSTRALIA |
Pavlov University | RUSSIAN FEDERATION |
Pfizer Worldwide Research and Development | UNITED STATES |
Pierre and Marie Curie University | FRANCE |
Queensland Institute of Medical Research | AUSTRALIA |
Queensland University of Technology | AUSTRALIA |
Regina Elena National Cancer Institute | ITALY |
Ritsumeikan University | JAPAN |
RMIT University | AUSTRALIA |
Royal Adelaide Hospital | AUSTRALIA |
SA Pathology | AUSTRALIA |
SA Water Corporation | AUSTRALIA |
Sapienza University of Rome | ITALY |
South Australian Health and Medical Research Institute (SAHMRI) | AUSTRALIA |
St. Jude Children's Research Hospital | UNITED STATES |
Stanford University | UNITED STATES |
State University of New York Buffalo | UNITED STATES |
Technion Israel Institute of Technology | ISRAEL |
The Hospital for Sick Children | CANADA |
The Institut Pasteur (AKA L'Institut Pasteur) | FRANCE |
Thomas Jefferson University | UNITED STATES |
Tokyo Medical Dental University | JAPAN |
Tokyo Medical University | JAPAN |
University of Adelaide | AUSTRALIA |
University Of Angers | FRANCE |
University of Cambridge | UNITED KINGDOM |
University of Cologne | GERMANY |
University of Geneva | SWITZERLAND |
University of Iowa | UNITED STATES |
University of Konstanz | GERMANY |
University of Lausanne | SWITZERLAND |
University of London | UNITED KINGDOM |
University of Massachusetts Amherst | UNITED STATES |
University of Massachusetts Medical School | UNITED STATES |
University of Melbourne | AUSTRALIA |
University of Michigan | UNITED STATES |
University of Michigan-Ann Arbor | UNITED STATES |
University of Minnesota, Twin Cities | UNITED STATES |
University of New South Wales | AUSTRALIA |
University of Newcastle | AUSTRALIA |
University of Otago | NEW ZEALAND |
University Of Paris Sud (Paris 11) | FRANCE |
University of Pennsylvania | UNITED STATES |
University of Pittsburgh | UNITED STATES |
University of Queensland | AUSTRALIA |
University of Rome Tor Vergata | ITALY |
University of South Australia | AUSTRALIA |
University of Sydney | AUSTRALIA |
University of Texas Southwestern Medical Center | UNITED STATES |
University of Western Australia | AUSTRALIA |
University of Zurich | SWITZERLAND |
Walter and Eliza Hall Institute of Medical Research | AUSTRALIA |
Weill Cornell Medical College | UNITED STATES |
Weill Cornell Medicine | UNITED STATES |
External engagement & recognition
Engagement/recognition | Year |
---|---|
South Australian Scientist of the Year, 2020SA Science Excellence and Innovation Awards |
2021 |
Fellowship Selection CommitteeAustralian Academy of Science |
2020 |
Member, National Committee for Biomedical SciencesAustralian Academy of Science |
2020 |
Fellowship Selection CommitteeAustralian Academy of Science |
2019 |
Member, National Committee for Biomedical SciencesAustralian Academy of Science |
2019 |
PresidentAustralia and New Zealand Society for Cell and Developmental Biology |
2019 |
Scientist of the year - nominationSA Science Excellence Awards |
2019 |
Affiliate Professor of MedicineThe University of Adelaide |
2018 |
Associate EditorMolecular and Cellular Oncology |
2018 |
Board MemberInternational Cell Death Society |
2018 |
Committee member, Assigners AcademyNational Health and Medical Research Council (NHMRC) |
2018 |
Editorial Advisory BoardOncotarget |
2018 |
Editorial Board MemberCell Death and Differentiation |
2018 |
Editorial Board MemberScienceOPEN |
2018 |
Editorial Board MemberFrontiers in Cancer Molecular Targets and Therapeutics |
2018 |
Fellowship Selection CommitteeAustralian Academy of Science |
2018 |
Finalist, South Australian Scientist of the Year AwardGovernment of South Australia |
2018 |
MemberAmerican Society for Biochemistry and Molecular Biology |
2018 |
MemberAustralian Society for Biochemistry and Molecular Biology (ASBMB) |
2018 |
MemberEuropean Cell Death Organization |
2018 |
MemberJapan Society for the Promotion of Science Alumni Association in Australia (JSPSAAA) |
2018 |
MemberFaculty of 1000 |
2018 |
MemberResearch Strategy Group of the Beat Cancer Project |
2018 |
Member of the Order of Australia (AM)Order of Australia |
2018 |
Member, National Committee for Biomedical SciencesAustralian Academy of Science |
2018 |
PresidentAustralia and New Zealand Society for Cell and Developmental Biology |
2018 |
SAIMA President AwardSouth Australian Indian Medical Association (SAIMA) |
2018 |
Affiliate Professor of MedicineThe University of Adelaide |
2017 |
Associate EditorMolecular and Cellular Oncology |
2017 |
Committee member, Assigners AcademyNational Health and Medical Research Council (NHMRC) |
2017 |
Editorial Advisory BoardOncotarget |
2017 |
Editorial Board MemberCell Death and Differentiation |
2017 |
Editorial Board MemberScienceOPEN |
2017 |
Editorial Board MemberFrontiers in Cancer Molecular Targets and Therapeutics |
2017 |
Fellowship Selection CommitteeAustralian Academy of Science |
2017 |
MemberAmerican Society for Biochemistry and Molecular Biology |
2017 |
MemberAustralian Society for Biochemistry and Molecular Biology (ASBMB) |
2017 |
MemberEuropean Cell Death Organization |
2017 |
MemberJapan Society for the Promotion of Science Alumni Association in Australia (JSPSAAA) |
2017 |
MemberFaculty of 1000 |
2017 |
MemberResearch Strategy Group of the Beat Cancer Project |
2017 |
Member, National Committee for Biomedical SciencesAustralian Academy of Science |
2017 |
PresidentAustralia and New Zealand Society for Cell and Developmental Biology |
2017 |
President-elect and council memberAustralia and New Zealand Society for Cell and Developmental Biology |
2017 |
President-elect and council memberAustralia and New Zealand Society for Cell and Developmental Biology |
2016 |
President's MedalAustralia and New Zealand Society for Cell and Developmental Biology |
2016 |
Senior Principal Research FellowshipNational Health and Medical Research Council (NHMRC) |
2016 |
FellowAustralian Academy of Health and Medical Science |
2015 |
FellowshipAustralia and New Zealand Society for Cell and Developmental Biology |
2015 |
Member, Grant Reviewing PanelsNational Health and Medical Research Council (NHMRC) |
2015 |
President-elect and council memberAustralia and New Zealand Society for Cell and Developmental Biology |
2015 |
Committee member, Assigners AcademyNational Health and Medical Research Council (NHMRC) |
2014 |
Committee member, Assigners AcademyNational Health and Medical Research Council (NHMRC) |
2013 |
FellowAustralian Academy of Science |
2013 |
Lamberg MedalAustralian Society for Biochemistry and Molecular Biology (ASBMB) |
2013 |
Member of learned academyAustralian Academy of Science |
2013 |
Research ExcellenceFederation of Asian and Oceanian Biochemists and Molecular Biologists |
2013 |
Committee member, Assigners AcademyNational Health and Medical Research Council (NHMRC) |
2012 |
Editorial Boards, Advisory Committees, Professional Societies and Peer Review Panels
Member, Selection Committee for the AAHMS Jian Zhou Medal (2023-2025)
Member, Program Committee for 26th Congress of IUBMB (2022-2024)
Member, Award Selection Panel, Australasian Society of Cell Death (2020, 2021, 2022)
Member, Australian Academy of Science National Committee for Biomedical Sciences (2017- current)
Member, Beat Cancer Project Research Strategy Group, Cancer Council SA (2017- current)
Member of the Board, International Society of Cell Death (2018- current)
Member, Steering Committee of Research Centre for Extracellular Vesicles (RCEV) (2021- current)
Member, Selection Panel, SA Science Excellence and Innovation Awards (2021, 2022, 2023)
ACDS Pioneer and Advisor, Australasian Cell Death Society (2020- current)
Member, International Society of Extracellular Vesicles (2020- current)
Member, American Society for Biochemistry and Cell Biology (ASBMB) (1997- current)
Member, Australian Society for Biochemistry and Cell Biology (ASBMB) (1996- current)
Member, American Association for Advancement of Science (AAAS) (1995- current)
Member, Ausbiotech (2019- current)
Member, National Association of Research Fellows (NARF) (Since 2000)
Member, Editorial Board, Cell Death & Differentiation (1996- current)
Member, Faculty of 1000 (2001- current)
Member, ANZSCDB Committee (2019- current)
Executive and Past-President, ANZSCDB (2019-2021)
President, Australia and New Zealand Society for Cell and Developmental Biology (ANZSCDB) (2017-2019)
Member, AAS Sectional Committee SC8 (2017-2020)
Member, NHMRC Investigator Grants Review Panel (2019, 2022, 2023)
Member, NHMRC Assigners Academy (2012, 2013, 2014, 2017, 2018)
Member, NHMRC Grant Reviewing Panels (GRP) (2001, 2002, 2004, 2010, 2011, 2015)
Member, NHMRC Academy (2011)
Member, Cancer Australia Grant Review Panel (2009)
Member, RAH/IMVS Research Committee (2005-2009)
Chair, RAH/IMVS Research Fellowship Sub-Committee (2005-2009)
Chair, NHMRC GRP (2006, 2007)
Deputy Chair, NHMRC GRP (2005)
Member, Cancer Council Research Advisory Committee (1999-2001)
Member, NHMRC Regional Grants Interviewing Committee (1999)
Teaching & student supervision
Supervisions from 2010 shown
Thesis title | Student status |
---|---|
High fat diets and breast cancer | Current |
Investigating the functions of the ubiquitin ligase NEDD4-2 in kidney disease. | Current |
Modulation of NEDD4-2 expression and activity as a cellular mechanism for ameliorating kidney disease | Current |
Regulation of autophagy in cell and tissue homeostasis | Current |
Analysis of Arrdc4 ubiquitination and its function in extracellular vesicles biogenesis | Completed |
Deciphering the role of caspase-2 in protecting against genetic instability and tumour suppression | Completed |
Identifying regulators of autophagy-dependent cell death | Completed |
Investigating the role of NEDD4 in neural crest cell development and craniofacial bone formation | Completed |
Regulation and mechanism of autophagy-dependent developmental cell death in Drosophila melanogaster larval midgut | Completed |
Regulation of retromer and its role in tauopathies | Completed |