Dr Stanley Yu

Adjunct Associate Research Professor Centre for Cancer Biology

City West Campus (HB9-27)
tel +61 8 830 27819

email Stanley.Yu@unisa.edu.au

Research

Research focus

Biological Sciences
Immunology
Medical and Health Sciences
Agricultural and Veterinary Sciences
Biochemistry and Cell Biology

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Journal Articles

Year	Output
2024	Gargett, T, Truong, NT, Gardam, B, Yu, W, Ebert, LM, Johnson, A, Yeo, EC, Wittwer, NL, Tapia Rico, G, Logan, J, Sivaloganathan, P, Collis, M, Ruszkiewicz, A & Brown, MP 2024, 'Safety and biological outcomes following a phase 1 trial of GD2-specific CAR-T cells in patients with GD2-positive metastatic melanoma and other solid cancers', Journal for ImmunoTherapy of Cancer, vol. 12, no. 5, pp. 1-17. Open access 8
2024	Yu, W, Truong, NT, Polara, R, Gargett, T, Tea, MN, Pitson, SM, Cockshell, MP, Bonder, CS, Ebert, LM & Brown, MP 2024, 'Endogenous bystander killing mechanisms enhance the activity of novel FAP-specific CAR-T cells against glioblastoma', Clinical and Translational Immunology, vol. 13, no. 7, pp. 1-20. Open access 2 2 4
2023	Yu, W, Gargett, T & Du, Z 2023, 'A Poisson distribution-based general model of cancer rates and a cancer risk-dependent theory of aging', Aging, vol. 15, no. 17, pp. 8537-8551. Open access 1 1
2022	Gargett, T, Ebert, LM, Truong, NT, Kollis, PM, Sedivakova, K, Yu, W, Yeo, EC, Wittwer, NL, Gliddon, BL, Tea, MN, Ormsby, R, Poonnoose, S, Nowicki, J, Vittorio, O, Ziegler, DS, Pitson, SM & Brown, MP 2022, 'GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma', Journal for ImmunoTherapy of Cancer, vol. 10, no. 9, article no. e005187, pp. 1-15. Open access 60 54
2021	El Khawanky, N, Hughes, A, Yu, W, Myburgh, R, Matschulla, T, Taromi, S, Aumann, K, Clarson, J, Vinnakota, JM, Shoumariyeh, K, Miething, C, Lopez, AF, Brown, MP, Duyster, J, Hein, L, Manz, MG, Hughes, TP, White, DL, Yong, AS & Zeiser, R 2021, 'Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia', Nature Communications, vol. 12, no. 1, article no. 6436, pp. 1-20. Open access 69 67
2020	Ebert, LM, Yu, W, Gargett, T, Toubia, J, Kollis, PM, Tea, MN, Ebert, BW, Bonder, CS, Oksdath Mansilla, M, Scheer, KG, Perrin, SL, Pitson, SM, Gomez, GA & Brown, MP and 8 other authors 2020, 'Endothelial, pericyte and tumor cell expression in glioblastoma identifies fibroblast activation protein (FAP) as an excellent target for immunotherapy', Clinical and Translational Immunology, vol. 9, no. 10, article no. e1191. Open access 50 44 4
2020	Mekonnen, ZA, Masavuli, MG, Yu, W, Gummow, J, Whelan, DM, Al-Delfi, Z, Torresi, J, Gowans, EJ & Grubor-Bauk, B 2020, 'Enhanced T cell responses induced by a necrotic dendritic cell vaccine, expressing HCV NS3', Frontiers in Microbiology, vol. 11, article no. 559105, pp. 1-13. Open access 6 4
2019	Gargett, T, Truong, N, Ebert, LM, Yu, W & Brown, MP 2019, 'Optimization of manufacturing conditions for chimeric antigen receptor T cells to favor cells with a central memory phenotype', Cytotherapy, vol. 21, no. 5, pp. 593-602. 28 29
2018	Ebert, LM, Yu, W, Gargett, T & Brown, MP 2018, 'Logic-gated approaches to extend the utility of chimeric antigen receptor T-cell technology', Biochemical Society Transactions, vol. 46, no. 2, pp. 391-401. 24 23
2018	Wijesundara, DK, Gummow, J, Li, Y, Yu, W, Quah, BJ, Ranasinghe, C, Torresi, J, Gowans, EJ & Grubor-Bauk, B 2018, 'Induction of genotype cross-reactive, hepatitis C virus-specific, cellmediated immunity in DNA-vaccinated mice', Journal of Virology, vol. 92, no. 8, article no. e02133-17, pp. 1-15. Open access 21 22
2017	Wijesundara, DK, Yu, W, Quah, BJ, Eldi, P, Hayball, JD, Diener, KR, Voskoboinik, I, Gowans, EJ & Grubor-Bauk, B 2017, 'Cytolytic DNA vaccine encoding lytic perforin augments the maturation of - and antigen presentation by - dendritic cells in a time-dependent manner', Scientific Reports, vol. 7, no. 1, article no. 8530, pp. 1-8. Open access 7 8 1
2016	Gargett, T, Yu, W, Dotti, G, Yvon, ES, Christo, SN, Hayball, JD, Lewis, ID, Brenner, MK & Brown, MP 2016, 'GD2-specific CAR T cells undergo potent activation and deletion following antigen encounter but can be protected from activation-induced cell death by PD-1 blockade', Molecular Therapy, vol. 24, no. 6, pp. 1135-1149. Open access 299 275 11
2016	Grubor-Bauk, B, Yu, W, Wijesundara, D, Gummow, J, Garrod, T, Brennan, A, Voskoboinik, I & Gowans, E 2016, 'Intradermal delivery of DNA encoding HCV NS3 and perforin elicits robust cell-mediated immunity in mice and pigs', Gene Therapy (Basingstoke), vol. 23, no. 1, pp. 26-37. Open access 25 24
2015	Gummow, J, Yanrui, L, Wenbo, Y, Garrod, T, Wijesundara, D, Brennan, AJ, Mullick, R, Voskoboinik, I, Grubor-Bauk, B & Gowansa, EJ 2015, 'A multiantigenic DNA vaccine that induces broad hepatitis C virus-specific T-Cell responses in mice', Journal of Virology, vol. 89, no. 15, pp. 7991-8002. Open access 22 24
2015	Tomusange, K, Yu, W, Suhrbier, A, Wijesundara, D, Grubor-Bauk, B & Gowans, EJ 2015, 'Engineering human rhinovirus serotype-A1 as a vaccine vector', Virus Research, vol. 203, pp. 72-76. 7 6
2014	Gargett, T, Bruber-Bauk, B, Garrod, T, Yu, W, Miller, DS, Major, L, Wesselingh, S, Suhrbier, A & Gowans, E 2014, 'Induction of antigen-positive cell death by the expression of Perforin, but not DTa, from a DNA vaccine enhances the immune response', Immunology and Cell Biology, vol. 92, no. 4, pp. 359-367. 23 24
2014	Gargett, T, Grubor-Bauk, B, Miller, D, Garrod, T, Yu, S, Wesselingh, S, Suhrbier, A & Gowans, EJ 2014, 'Increase in DNA vaccine efficacy by virosome delivery and co-expression of a cytolytic protein', Clinical and Translational Immunology, vol. 3, article no. e18, pp. 1-7. Open access 22
2014	Garrod, T, Grubor-Bauk, B, Yu, S, Gargett, T & Gowans, EJ 2014, 'Encoded novel forms of HSP70 or a cytolytic protein increase DNA vaccine potency', Human Vaccines and Immunotherapeutics, vol. 10, no. 9, pp. 2679-2683. Open access 10 10
2014	Garrod, TJ, Bruber-Bauk, B, Gargett, T, Li, Y, Miller, DS, Wenbo, Y, Major, L, Burrell, CJ, Wesselingh, S, Suhrbier, A & Gowans, EJ 2014, 'DNA vaccines encoding membrane-bound or secreted forms of heat shock protein 70 exhibit improved potency', European Journal of Immunology, vol. 44, no. 7, pp. 1992-2002. Open access 22 19
2014	Garrod, TJ, Gargett, T, Yu, W, Major, L, Burrell, CJ, Wesselingh, S, Suhrbier, A, Grubor-Bauk, B & Gowans, EJ 2014, 'Loss of long term protection with the inclusion of HIV pol to a DNA vaccine encoding gag', Virus Research, vol. 192, pp. 25-33. 6 6
2014	Yu, W, Grubor-Bauk, B, Gargett, T, Garrod, T & Gowans, EJ 2014, 'A novel challenge model to evaluate the efficacy of hepatitis C virus vaccines in mice', Vaccine, vol.32, no. 27, pp. 3409-3416. 16 15
2014	Yu, W, Grubor-Bauk, B, Mullick, R, Das, S & Gowans, EJ 2014, 'Immunocompetent mouse models to evaluate intrahepatic T cell responses to HCV vaccines', Human Vaccines and Immunotherapeutics, vol. 10, no. 12, pp. 3576-3578. Open access 3 2
2013	Xiao, H, Liu, L, Zhu, Q, Tan, Z, Yu, W, Tang, X, Zhan, D, Du, Y, Wang, H, Liu, D, Li, Z, Yuen, K-Y, Ho, DD, Gao, GF & Chen, Z 2013, 'A replicating modified Vaccinia Tiantan strain expressing an avian-derived influenza H5N1 hemagglutinin induce broadly neutralizing antibodies and cross-clade protective immunity in mice', PLoS One, vol. 8, no. 12, article no. e83274, pp. 1-10. Open access 10 10
2013	Zhou, J, Cheung, AK, Tan, Z, Wang, H, Yu, W, Du, Y, Kang, Y, Lu, X, Liu, L, Yuen, K-Y & Chen, Z 2013, 'PD1-based DNA vaccine amplifies HIV-1 GAG-specific CD8(+) T cells in mice', Journal of Clinical Investigation, vol. 123, no. 6, pp. 2629-2642. Open access 57 48
2011	Lu, B, Yu, W, Huang, X, Wang, H, Liu, L & Chen, Z 2011, 'Mucosal immunization induces a higher level of lasting neutralizing antibody response in mice by a replication-competent smallpox vaccine: Vaccinia Tiantan strain', BioMed Research International, vol. 2011, article no. 970424, pp. 1-9. Open access 12 12
2011	Yu, W-b, Liu, L & Chen, Z-w 2011, 'Attenuation of the smallpox vaccine Vaccinia Tiantan strain and its use as a safe vaccine live vector', Chinese Journal of Viral Diseases, vol. 1, no. 1, pp. 75-80.
2010	Liu, H, Yu, W, Tang, X, Wang, H, Ouyang, W, Zhou, J & Chen, Z 2010, 'The route of inoculation determines the tissue tropism of modified vaccinia Tiantan expressing the spike glycoprotein of SARS-CoV in mice', Journal of Medical Virology, vol. 82, no. 5, pp. 727-734. Open access 12 11
2009	Huang, X, Lu, B, Yu, W, Fang, Q, Liu, L, Zhuang, K, Shen, T, Wang, H, Tian, P, Zhang, L & Chen, Z 2009, 'A novel replication-competent vaccinia vector MVTT Is superior to MVA for inducing high levels of neutralizing antibody via mucosal vaccination', PLoS One, vol. 4, no. 1, article no. e4180, pp. 1-9. Open access 45 41
2009	Yu, W, Fang, Q, Zhu, W, Wang, H, Tien, P, Zhang, L & Chen, Z 2009, 'One time intranasal vaccination with a modified vaccinia Tiantan strain MVTTZCI protects animals against pathogenic viral challenge', Vaccine, vol. 28, no. 9, pp. 2088-2096. Open access 22 20

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Academy of Military Medical Sciences	CHINA
Australian National University	AUSTRALIA
Chinese Academy of Medical Sciences	CHINA
Chinese Academy of Sciences	CHINA
Flinders Medical Centre	AUSTRALIA
Flinders University	AUSTRALIA
Houston Methodist Hospital	UNITED STATES
Indian Institute of Science	INDIA
John Curtin School of Medical Research	AUSTRALIA
Peter MacCallum Cancer Centre	AUSTRALIA
QIMR Berghofer Medical Research Institute	AUSTRALIA
Queensland Institute of Medical Research	AUSTRALIA
Rockefeller University	UNITED STATES
Royal Adelaide Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
South Australian Health and Medical and Research Institute (SAHMRI)	AUSTRALIA
Sydney Children's Hospital	AUSTRALIA
Tsinghua University	CHINA
University Medical Centre Freiburg	GERMANY
University of Adelaide	AUSTRALIA
University of Freiburg	GERMANY
University of Hong Kong	HONG KONG
University of Melbourne	AUSTRALIA
University of New South Wales	AUSTRALIA
University of North Carolina at Chapel Hill	UNITED STATES
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Texas	UNITED STATES
University of Zurich	SWITZERLAND
Wuhan University	CHINA

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Dr Stanley Yu

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Journal Articles

External engagement & recognition

Collaborations

Collaborations

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