I am a Senior Research Fellow in the Quality Use of Medicines and Pharmacy Research Centre. I have a background in pharmacy and natural products chemistry. My research interests include Australian medicinal and food plants with an emphasis on research which is in partnership with Australian Aboriginal organisations and driven by these organisations. Currently our work is examining the health benefits of, and product development from, some traditional medicinal and food plants. We focus on plants with antibacterial, anti-inflammatory and anti-diabetic activities.
I also collaborate with researchers at the University of Copenhagen in Denmark and Shandong University in China.
I have also conducted research in the areas of complementary ... Read more
About me
I am a Senior Research Fellow in the Quality Use of Medicines and Pharmacy Research Centre. I have a background in pharmacy and natural products chemistry. My research interests include Australian medicinal and food plants with an emphasis on research which is in partnership with Australian Aboriginal organisations and driven by these organisations. Currently our work is examining the health benefits of, and product development from, some traditional medicinal and food plants. We focus on plants with antibacterial, anti-inflammatory and anti-diabetic activities.
I also collaborate with researchers at the University of Copenhagen in Denmark and Shandong University in China.
I have also conducted research in the areas of complementary medicine use in the community and medication safety
About me
Royal Australian Chemical Institute: North Melbourne, Victoria, Australia
Australian Society for Microbiology: VIC, Australia
American Chemical Society: Washington, DC, US
About me
Doctor of Philosophy (Health Sciences) University of South Australia
Bachelor of Pharmacy University of South Australia
2014 (to Present) Senior Research Fellow (0.5-0.6 FTE), Quality Use of Medicines and Pharmacy Research Centre & School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia
2005 – 2013 Research Fellow, Quality Use of Medicines and Pharmacy Research Centre, Sansom Institute for Health Research, University of South Australia, Adelaide, Australia (0.5 FTE 2009-2014)
2002 - 2005 Research Associate Quality Use of Medicines and Pharmacy Research Centre, Sansom Institute, University of South Australia
1999-2001 Research Assistant, Quality Use of Medicines and Pharmacy Research Centre, University of South Australia
1995-1999 Lecturer and tutor (Casual), School of Pharmacy and Medical Sciences
1993-1994 Clinical trial co-ordinator, Gastroenterology Department, Women’s and Children’s Hospital, Adelaide
Current research projects include
Australian Research Council, Linkage Grant (2024-27) Co-research supporting the development of Aboriginal plant knowledges LP220200369 Role: CIA.
Australian Research Council, Linkage Grant (2024-2027) Finding the targets of natural products in complex botanical extracts LP230100225 (Led by Prof David Adelson, University of Adelaide). Role: CI.
Medical Research Future Fund (MRFF) Indigenous Health Research (2023-2025) A bush foods programme to facilitate cultural connections and nutrition knowledges for Aboriginal young people (Led by Michael Watkins, Dept of Rural Health, UniSA). Role CI.
Quality Use of Diagnostics, Therapeutic and Pathology Program (2023-2025), Health Professional Education... Read more
Research
Excludes commercial-in-confidence projects.
Finding the targets of natural products in complex botanical extracts, Shanxi Zhendong Pharmaceuticals Co Ltd, 01/01/2024 - 31/12/2026
Finding the targets of natural products in complex botanical extracts, ARC - Linkage Project, 01/01/2024 - 31/12/2026
Development of antibacterial and anti-inflammatory compounds, Wound Management Innovation CRC, 01/09/2013 - 31/12/2016
RP2.13 - Optimised serrulatane bioactives from Eremophila plants, Wound Management Innovation CRC, 01/07/2013 - 30/12/2016
Research
Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID, ResearcherID or Scopus
Open access indicates that an output is open access.
Year | Output |
---|---|
2023 |
5
5
|
2022 |
Open access
3
3
|
2021 |
Open access
12
14
50
|
2021 |
Open access
9
9
110
|
2020 |
21
21
|
Year | Output |
---|---|
2015 |
1
|
2012 |
Open access
|
Year | Output |
---|---|
2024 |
Open access
|
2024 |
Open access
|
2023 |
4
4
6
|
2023 |
Open access
3
|
2023 |
Open access
3
3
|
2023 |
2
2
3
|
2023 |
5
5
|
2023 |
2
2
|
2022 |
Open access
6
6
|
2022 |
Open access
9
12
5
|
2022 |
Open access
49
45
206
|
2022 |
Open access
10
10
|
2022 |
Open access
2
2
|
2022 |
Open access
3
3
|
2021 |
Open access
12
14
50
|
2021 |
13
11
1
|
2021 |
1
1
|
2021 |
9
16
1
|
2021 |
Open access
9
9
110
|
2020 |
Open access
12
12
2
|
2020 |
8
9
|
2020 |
21
21
|
2020 |
5
5
1
|
2020 |
15
11
|
2020 |
13
10
|
2019 |
Open access
15
11
1
|
2019 |
14
12
1
|
2018 |
29
27
1
|
2018 |
7
4
|
2018 |
22
22
|
2018 |
20
18
|
2017 |
Open access
2
1
|
2017 |
29
27
|
2017 |
4
5
2
|
2017 |
17
16
9
|
2017 |
23
24
3
|
2016 |
Open access
16
14
32
|
2016 |
Open access
32
27
5
|
2016 |
Open access
112
99
13
|
2016 |
Open access
4
4
4
|
2015 |
Open access
22
22
19
|
2015 |
21
15
12
|
2015 |
Open access
7
7
|
2014 |
Open access
21
20
|
2013 |
Open access
16
11
|
2012 |
Open access
37
34
|
2012 |
10
11
|
2012 |
Open access
16
16
|
2011 |
28
26
|
2011 |
27
21
|
2010 |
1
|
2010 |
32
29
|
2009 |
Open access
98
82
|
2009 |
84
79
|
2009 |
Open access
154
|
2009 |
Open access
41
|
2008 |
Open access
|
2008 |
|
2008 |
Open access
7
6
|
Year | Output |
---|---|
2022 |
Open access
|
2020 |
Open access
|
2019 |
Open access
|
Research
Current research projects include
Australian Research Council, Linkage Grant (2024-27) Co-research supporting the development of Aboriginal plant knowledges LP220200369 Role: CIA.
Australian Research Council, Linkage Grant (2024-2027) Finding the targets of natural products in complex botanical extracts LP230100225 (Led by Prof David Adelson, University of Adelaide). Role: CI.
Medical Research Future Fund (MRFF) Indigenous Health Research (2023-2025) A bush foods programme to facilitate cultural connections and nutrition knowledges for Aboriginal young people (Led by Michael Watkins, Dept of Rural Health, UniSA). Role CI.
Quality Use of Diagnostics, Therapeutic and Pathology Program (2023-2025), Health Professional Education Grant, UniSA-led Research Consortium Program Medicines Advice Initiative Australia. Role CI
Research
Details | Registry | Status |
---|---|---|
Semple, Susan J; Simpson, Bradley S; McKinnon, Ross Allan; Claudie, David; Gerber, Jacobus P; Wang, Jiping; Moreton, George Sr |
EP | Filed |
Semple, Susan J; Simpson, Bradley S; McKinnon, Ross Allan; Claudie, David; Gerber, Jacobus P; Wang, Jiping; Moreton, George Sr |
US | Filed |
Semple, Susan J; Simpson, Bradley S; McKinnon, Ross Allan; Claudie, David; Gerber, Jacobus P; Wang, Jiping; Moreton, George Sr |
WO | Filed |
Griesser, Hans Jörg; Ndi, Chi Pius; Semple, Susan Jean; Ys, Hardi |
WO | Filed |
External engagement & recognition
Organisation | Country |
---|---|
Ayurvedic Government Medical College | INDIA |
Chuulangun Aboriginal Corporation | AUSTRALIA |
Flinders Medical Centre | AUSTRALIA |
Flinders University | AUSTRALIA |
Monash University | AUSTRALIA |
Nelumbo Botaniks | AUSTRALIA |
Qingdao University | CHINA |
ReaLi Tide Biological Technology (Weihai) Co. Ltd | CHINA |
Robert Mathys Stiftung | SWITZERLAND |
Royal Botanic Gardens Melbourne | AUSTRALIA |
Shandong Center for Disease Control and Prevention | CHINA |
Shandong University | CHINA |
State Herbarium of South Australia | AUSTRALIA |
Technical University of Denmark | DENMARK |
University of Adelaide | AUSTRALIA |
University of Copenhagen | DENMARK |
University of Melbourne | AUSTRALIA |
University of Queensland | AUSTRALIA |
University of South Australia | AUSTRALIA |
University of Western Australia | AUSTRALIA |
Wise Owl Consulting | AUSTRALIA |
Zaozhuang University | CHINA |
External engagement & recognition
Engagement/recognition | Year |
---|---|
Research models for benefit sharing with an Aboriginal groupQueensland Government (review of Biodiscovery Act) |
2019 |
Co-led a collaborative project entitled the Kuuku Iyu Medicinal Plants ProjectChuulangun Aboriginal Corporation; World Intellectual Property Organization; IP Australia; Queensland Government |
2018 |
Keynote speaker APSA Lecture at annual conferenceAustralasian Pharmaceutical Science Association (APSA) |
2018 |
Teaching & student supervision
Supervisions from 2010 shown
Thesis title | Student status |
---|---|
Exploring the role of bush foods on the cultural health and wellbeing for Aboriginal Peoples | Current |
Preventing chronic infection in Cystic Fibrosis patients with a repurposed drug that inhibits antibiotic efflux pumps | Current |
A combined in silico and microbiological approach for the identification of novel efflux pump inhibitors against AcrAB-TolC | Completed |
Advanced glycation end product induced genotoxicity and receptor expression in human cells | Completed |
Antibacterial coatings for biomedical devices by covalent grafting of serrulatane diterpenes | Completed |
Antibacterial serrulatanes: synthetic studies and structure-activity relationships | Completed |
Biological actions of antibacterial compounds covalently attached onto solid material surfaces or released diffusively from materials | Completed |
Chemical and pharmacological investigation of Acacia and Santalum species | Completed |
Chemical and pharmacological investigation of Dodonaea polyandra | Completed |
Discovery of antibacterial compounds from Australian Eremophila plants | Completed |
Pharmacological and in silico investigation of anti-inflammatory diterpenoid compounds isolated from Dodonaea polyandra | Completed |
Reversing antimicrobial resistance with inhibitors of drug efflux pumps | Completed |
Serrulatanes from eremophila neglecta: their spectrum of antibacterial activity, cytotoxicity and mode of action | Completed |
Spatial and molecular aspects of hemiparasites on Acacia spp. | Completed |
Targeting bacterial cellular division via FtsZ as an approach in the development of new antimicrobial agents | Completed |