Dr Winnie Kan

SENIOR RESEARCH OFFICER Centre for Cancer Biology

City West Campus (HB11-25)
tel +61 8 830 27933

email Winnie.Kan@unisa.edu.au

Research

Research focus

Biochemistry and Cell Biology
Oncology and Carcinogenesis
Clinical Sciences
Immunology
Multidisciplinary

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit Scopus

Open access indicates that an output is open access.

Chapters

Year	Output
2023	Shing, KS, Kan, WL, Nero, TL, Hercus, TR, Tvorogov, D, Metcalfe, RD, Griffin, MD, De Weerd, NA, Guthridge, MA, Hertzog, PJ, Lopez, AF & Parker, MW 2023, 'Cytokine receptors and their ligands', in Ralph A Bradshaw et al. (eds), Encyclopedia of Cell Biology, 2nd, Elsevier, UK, vol. 4, pp. 21-45. 2
2015	Dhagat, U, Nero, T, Kan, W, Hercus, T, Broughton, S, de Weerd, N, Jenkins, B, Mansell, A, Guthridge, M, Hertzog, P, Lopez, A & Parker, M 2015, 'Cytokine receptors and their ligands', Encyclopedia of cell biology, Academic Press, US, vol. 3, pp. 22-36.

Journal Articles

Year	Output
2025	Kan, WL, Weekley, CM, Nero, TL, Hercus, TR, Yip, KH, Tumes, DJ, Woodcock, JM, Ross, DM, Thomas, D, Terán, D, Owczarek, CM, Liu, NW, Martelotto, LG, Polo, JM, Pant, H, Tvorogov, D, Lopez, AF & Parker, MW 2025, 'The β common cytokine receptor family reveals new functional paradigms from structural complexities', Immunological Reviews, vol. 329, no. 1, pp. 1-25. Open access 1 1
2025	Toubia, J, Kusay, Y, Maqsood, M, Warnock, N I, Lawrence, DM, Bracken, CP, Gregory, PA, Kan, WL, Selth, LA, Conn, SJ, Lopez, AF, Branford, S, Scott, HS, Kok, CH, Goodall, GJ & Schreiber, AW 2025, 'TRanscriptome ANalysis of StratifiEd CohorTs (TRANSECT) enables automated assessment of global gene regulation linked to disparate expression in user defined genes and gene sets', NAR Genomics and Bioinformatics, vol. 7, no. 2, article no. lqaf041, pp. 1-13. Open access
2024	Kan, WL, McClure, BJ, Hahn, CN & Powell, JA 2024, 'The 10th Barossa meeting: cell signalling to cancer medicine', Cell Death and Disease, vol. 15, no. 3, article no. 230, pp. 1-3. Open access 1
2024	Lim, K, Kan, WL, Nair, PC, Kutyna, M, Lopez, AF, Hercus, T, Ross, DM, Lane, S, Fong, CY, Brown, A, Yong, A, Yeung, D, Hughes, T, Hiwase, D & Thomas, D 2024, 'CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: implications for targeting', PLoS One, vol. 19, no. 9, pp. 1-19. Open access
2023	Kan, WL, Dhagat, U, Kaufmann, KB, Hercus, TR, Toubia, J, Barry, EF, Gomez, GA, Dottore, M, Samaraweera, SE, Goodall, GJ, Thomas, D, Tvorogov, D, D'Andrea, RJ & Lopez, AF and 12 other authors 2023, 'Distinct assemblies of heterodimeric cytokine receptors govern stemness programs in leukemia', Cancer Discovery, vol. 13, no. 8, pp. 1922-1947. Open access 8 7 19
2021	Kan, WL, Cheung Tung Shing, KS, Nero, TL, Hercus, TR, Tvorogov, D, Parker, MW & Lopez, AF 2021, 'Messing with βc: a unique receptor with many goals', Seminars in Immunology, vol. 54, article 101513, pp. 1-14. Open access 4 4 3
2018	Broughton, SE, Hercus, TR, Nero, TL, Kan, WL, Barry, EF, Dottore, M, Cheung Tung Shing, KS, Morton, CJ, Dhagat, U, Hardy, MP, Wilson, NJ, Downton, MT, Schieber, C, Hughes, TP, Lopez, AF & Parker, MW 2018, 'A dual role for the N-terminal domain of the IL-3 receptor in cell signalling', Nature Communications, vol. 9, no. 1, article no. 386, pp. 1-15. Open access 33 33
2018	Hercus, TR, Kan, WL, Broughton, SE, Tvorogov, D, Ramshaw, HS, Thompson, EJ, McKenzie, DR, Tergaonkar, V, Hughes, T, Samuel, MS, Bonder, CS, Grimbaldeston, MA & Lopez, A F and 10 other authors 2018, 'Role of the β common (βc) family of cytokines in health and disease', Cold Spring Harbor Perspectives in Biology, vol. 10, no. 6, article no. a028514, pp. 1-26. Open access 36 28 14
2018	Tvorogov, D, Thomas, D, Liau, NP, Dottore, M, Barry, EF, Lathi, M, Kan, WL, Hercus, TR, Stomski, F, Hughes, TP, Tergaonkar, V, Parker, MW, Ross, DM, Majeti, R, Babon, JJ & Lopez, AF 2018, 'Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis', Science Advances, vol. 4, no. 11, article no. eaat3834, pp. 1-13. Open access 41 40 3
2015	Broughton, SE, Nero, TL, Dhagat, U, Kan, WL, Hercus, TR, Tvorogov, D, Lopez, AF & Parker, MW 2015, 'The βc receptor family - Structural insights and their functional implications', Cytokine, vol. 74, no. 2, pp. 247-258. 68 60 3
2014	Broughton, SE, Hercus, TR, Hardy, MP, McClure, BJ, Nero, TL, Dottore, M, Huyhn, H, Braley, H, Barry, EF, Kan, WL, Dhagat, U, Scotney, P, Hartman, D, Busfield, SJ, Owczarek, CM, Nash, AD, Wilson, NJ, Parker, MW & Lopez, AF 2014, 'Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody', Cell Reports, vol. 8, no. 2, pp. 410-419. Open access 52 45
2013	Hercus, TR, Dhagat, U, Kan, WL, Broughton, SE, Nero, TL, Perugini, M, Sandow, JJ, D'Andrea, RJ, Ekert, PG, Hughes, T, Parker, MW & Lopez, AF 2013, 'Signalling by the βc family of cytokines', Cytokine and Growth Factor Reviews, vol. 24, no. 3, pp. 189-201. Open access 83 76

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Austin Health	AUSTRALIA
CSL Limited	AUSTRALIA
Deakin University	AUSTRALIA
Flinders University	AUSTRALIA
Hudson Institute of Medical Research	AUSTRALIA
IBM Australia	AUSTRALIA
Monash University	AUSTRALIA
QIMR Berghofer Medical Research Institute	AUSTRALIA
SA Pathology	AUSTRALIA
South Australian Health and Medical and Research Institute (SAHMRI)	AUSTRALIA
St. Vincent's Institute of Medical Research	AUSTRALIA
Stanford University	UNITED STATES
University Health Network	CANADA
University of Adelaide	AUSTRALIA
University of Melbourne	AUSTRALIA
University of South Australia	AUSTRALIA
Walter and Eliza Hall Institute of Medical Research	AUSTRALIA

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Dr Winnie Kan

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Research

Research focus

Projects

Outputs

Chapters

Journal Articles

External engagement & recognition

Collaborations

Collaborations

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