Dr Xanthe Strudwick is a Research Associate within the Regenerative Medicine Laboratories of the Future Industries Institute whose research is aimed at developing novel therapeutics for wound repair, reducing scar formation and understanding the mechanisms involved in tissue regeneration. Xanthe began her research into skin biology with Professor Cowin’s laboratory at the Women’s and Children’s Health Research Institute before the lab's move to UniSA. Xanthe was awarded her PhD from UniSA for her investigation of the role of the cytoskeletal protein Flightless I in tissue regeneration. Her current research is aimed at the development of a novel antibody based therapy to reduce... Read more
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Dr Xanthe Strudwick is a Research Associate within the Regenerative Medicine Laboratories of the Future Industries Institute whose research is aimed at developing novel therapeutics for wound repair, reducing scar formation and understanding the mechanisms involved in tissue regeneration. Xanthe began her research into skin biology with Professor Cowin’s laboratory at the Women’s and Children’s Health Research Institute before the lab's move to UniSA. Xanthe was awarded her PhD from UniSA for her investigation of the role of the cytoskeletal protein Flightless I in tissue regeneration. Her current research is aimed at the development of a novel antibody based therapy to reduce inflammation and prevent scar formation in burn wounds. Xanthe is also working with materials scientists and physical chemists to develop novel wound dressings and investigate the use of low-temperature, atmospheric-pressure plasmas for biological and medical applications.
Doctor of Philosophy University of South Australia
Bachelor of Health Science (Honours) (Medical and Pharmaceutical Biotechnology) University of South Australia
Excludes commercial-in-confidence projects.
Plasma activated hydrogel therapy for combatting antimicrobial resistance in chronic wounds, NHMRC - Ideas Grants, 01/01/2021 - 31/12/2023
Open access indicates that an output is open access.
Ahangar, P, Mills, S, Smith, L, Strudwick, X, Ting, A, Vaes, B & Cowin, A 2021, 'Treatment of murine partial thickness scald injuries with multipotent adult progenitor cells decreases inflammation and promotes angiogenesis leading to improved burn injury repair', Wound Repair and Regeneration, vol. 29, no. 3, pp. 380-392.
Open access 19
Haidari, H, Bright, R, Strudwick, XL, Garg, S, Vasilev, K, Cowin, AJ & Kopecki, Z 2021, 'Multifunctional ultrasmall AgNP hydrogel accelerates healing of S. aureus infected wounds', Acta Biomaterialia, vol. 128, pp. 420-434.
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Yang, GN, Ahangar, P, Strudwick, XL, Kopecki, Z & Cowin, AJ 2021, 'Overexpression of flii during murine embryonic development increases symmetrical division of epidermal progenitor cells', International Journal of Molecular Sciences, vol. 22, no. 15, article no. 8235, pp. 1-15.
Open access 1 2 2
Yang, GN, Strudwick, XL, Bonder, CS, Kopecki, Z & Cowin, AJ 2021, 'Increased expression of flightless I in cutaneous squamous cell carcinoma affects wnt/β-catenin signaling pathway', International Journal of Molecular Sciences, vol. 22, no. 24, article no. 13203, pp. 1-14.
Ahangar, P, Mills, SJ, Smith, LE, Strudwick, XL, Ting, AE, Vaes, B & Cowin, AJ 2020, 'Human multipotent adult progenitor cell-conditioned medium improves wound healing through modulating inflammation and angiogenesis in mice', Stem Cell Research and Therapy, vol. 11, no. 1, article no. 299, pp. 1-16.
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Cowin, AJ, Strudwick, XL, Mills, SJ, Hofma, BR, Ahangar, P, Fitridge, R & Thomas, HM 2020, 'Attenuation of flightless I increases human pericyte proliferation, migration and angiogenic functions and improves healing in murine diabetic wounds', International Journal of Molecular Sciences, vol. 21, no. 16, pp. 1-15.
Open access 4 4 5
Ravindran Girija, A, Palaninathan, V, Strudwick, X, Balasubramanian, S, Dasappan Nair, S & Cowin, AJ 2020, 'Collagen-functionalized electrospun smooth and porous polymeric scaffolds for the development of human skin-equivalent', RSC Advances: An International Journal to Further the Chemical Sciences, vol. 10, no. 45, pp. 26594-26603.
Open access 5 5
Strudwick, XL & Cowin, A 2020, 'Multifunctional roles of the actin-binding protein flightless I in inflammation, cancer and wound healing', Frontiers in Cell and Developmental Biology, vol. 8, article no. 603508 , pp. 1-22.
Open access 5 5 1
Strudwick, XL, Adams, DH, Pyne, NT, Samuel, MS, Murray, RZ & Cowin, AJ 2020, 'Systemic delivery of anti-integrin aL antibodies reduces early macrophage recruitment, inflammation, and scar formation in murine burn wounds', Advances in Wound Care, vol. 9, no. 12, pp. 637-648.
Open access 7 7 6
Yang, GN, Strudwick, XL, Bonder, C, Kopecki, Z & Cowin, AJ 2020, 'Effect of flightless I expression on epidermal stem cell niche during wound repair', Advances in Wound Care, vol. 9, no. 4, pp. 161-173.
Open access 7 9 1
Bhatia, R, Strudwick, X, Cowin, AJ & Szili, EJ 2018, 'Investigation of helium plasma jet-treated serum and cell media on the viability of skin cells', Journal of Biomaterials and Tissue Engineering, vol. 8, no. 6, pp. 892-899.
Fernandez, T, Strudwick, X, Al-Bataineh, S, Short, R, Cowin, A, Whittle, J & Smith, L 2018, 'Surfaces to enhance matrix deposition for wound healing', Wound Practice and Research, vol. 26, no. 4, pp. 201-209.
Open access 7 7 6
Oh, J-S, Strudwick, X, Short, RD, Ogawa, K, Hatta, A, Furuta, H, Gaur, N, Hong, S-H, Cowin, AJ, Fukuhara, H, Inoue, K, Ito, M, Charles, C, Boswell, RW, Bradley, JW, Graves, DB & Szili, EJ 2016, 'How plasma induced oxidation, oxygenation, and de-oxygenation influences viability of skin cells', Applied Physics Letters, vol. 109, no. 20, article no. 203701, pp. 1-5.
Open access 24 24 2
Martens, PJ, Ly, M, Adams, DH, Penzkover, KR, Strudwick, X, Cowin, AJ & Poole-Warren, LA 2015, 'In vivo delivery of functional Flightless I siRNA using layer-by-layer polymer surface modification', Journal of Biomaterials Applications, vol. 30, no. 3, pp. 257-268.
Strudwick, XL, Lang, DL, Smith, LE & Cowin, AJ 2015, 'Combination of low calcium with Y-27632 rock Inhibitor increases the proliferative capacity, expansion potential and lifespan of primary human keratinocytes while retaining their capacity to differentiate into stratified epidermis in a 3D skin model', PLoS One, vol. 10, no. 4, article no. e0123651, pp. 1-12.
Open access 25 22 9
Open access 5
Kopecki, Z, Arkell, RM, Strudwick, XL, Hirose, M, Ludwig, RJ, Kern, JS, Bruckner-Tuderman, L, Zillikens, D, Murrell, DF & Cowin, AJ 2011, 'Overexpression of the Flii gene increases dermal-epidermal blistering in an autoimmune ColVII mouse model of epidermolysis bullosa acquisita', Journal of Pathology, vol. 225, no. 3, pp. 401-413.
Open access 32 33
Adams, D, Ruzehaji, N, Strudwick, X, Greenwood, J, Campbell, H, Arkell, R & Cowin, A 2009, 'Attenuation of Flightless I, an actin-remodelling protein, improves burn injury repair via modulation of transforming growth factor (TGF)-β1 and TGF-β3', British Journal of Dermatology, vol. 161 no. 2, pp. 326-336.
Leitch, VD, Strudwick, XL, Matthaei, K I, Dent, LA & Cowin, AJ 2009, 'IL-5-overexpressing mice exhibit eosinophilia and altered wound healing through mechanisms involving prolonged inflammation', Immunology and Cell Biology, vol. 87 no. 2, pp. 131-140.
Adams, DH, Strudwick, XL, Kopecki, Z, Hooper-Jones, JA, Matthaei, K I, Campbell, HD, Powell, BC & Cowin, A 2008, 'Gender specific effects on the actin-remodelling protein Flightless I and TGF-β1 contribute to impaired wound healing in aged skin', The International Journal of Biochemistry and Cell Biology, vol. 40 no. 8, pp. 1555-1569.
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External engagement & recognition
|Athersys Inc||UNITED STATES|
|Athersys, Inc.||UNITED STATES|
|Australian National University||AUSTRALIA|
|John Curtin School of Medical Research||AUSTRALIA|
|Kochi Medical School||JAPAN|
|Kochi University of Technology||JAPAN|
|Lancaster University||UNITED KINGDOM|
|Queensland University of Technology||AUSTRALIA|
|Royal Adelaide Hospital||AUSTRALIA|
|University of Adelaide||AUSTRALIA|
|University of California||UNITED STATES|
|University of Freiburg||GERMANY|
|University of Liverpool||UNITED KINGDOM|
|University of Lubeck||GERMANY|
|University of New South Wales||AUSTRALIA|
|University of South Australia||AUSTRALIA|
|Women and Children's Health Research Institute||CANADA|
|Women's & Children's Health Research Institute Inc||AUSTRALIA|
|Women's and Children's Health Network||AUSTRALIA|
Supervisions from 2010 shown
|Thesis title||Student status|
|Alterations in bone -related gene expression pattern induced by growth and sex hormones in growing and ageing rats||Current|