Professor Yeesim Khew-Goodall

Adjunct Professor Centre for Cancer Biology

City West Campus (HB9-11)
tel +61 8 830 27741

email Yeesim.Khew-Goodall@unisa.edu.au

Research Degree Supervisor

Research

Research focus

Biological Sciences
Medical and Health Sciences
Biochemistry and Cell Biology
Clinical Sciences
Multidisciplinary

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID

Open access indicates that an output is open access.

Journal Articles

Year	Output
2023	Orang, A, Dredge, BK, Liu, CY, Bracken, JM, Chen, CH, Sourdin, L, Whitfield, HJ, Lumb, R, Boyle, ST, Davis, MJ, Samuel, MS, Gregory, PA, Khew-Goodall, Y, Goodall, GJ, Pillman, KA & Bracken, CP 2023, 'Basonuclin-2 regulates extracellular matrix production and degradation', Life Science Alliance, vol. 6, no. 10, article no. e202301984. Open access
2022	Lonic, A, Onglao, W & Khew-Goodall, Y 2022, 'Quantifying EGFR endosomal recycling via immunofluorescence in breast cancer cells', Star Protocols, vol. 3, no. 2, pp. 1-11. Open access
2022	Onglao, W, Khew-Goodall, Y, Belle, L & Lonic, A 2022, 'Aberrant post-translational modifications in endosomal trafficking are potential therapeutic targets to avert therapy resistance in solid cancers: Dysregulation of PTM-regulated endosomal interactions presents an opportunity to block oncogenic signalling from multiple receptors by targeting common trafficking pathways', BioEssays, vol. 44, no. 2, article no. 2100192, pp. 1-9.
2021	Lonic, A, Gehling, F, Belle, L, Li, X, Schieber, NL, Nguyen, E V, Goodall, GJ, Parton, RG, Daly, RJ & Khew-Goodall, Y 2021, 'Phosphorylation of PKCδ by FER tips the balance from EGFR degradation to recycling', The Journal of Cell Biology, vol. 220, no. 1, pp. 1-27. Open access 12 10 8
2021	Manning, JA, Shah, SS, Nikolic, A, Henshall, TL, Khew-Goodall, Y & Kumar, S 2021, 'The ubiquitin ligase NEDD4-2/NEDD4L regulates both sodium homeostasis and fibrotic signaling to prevent end-stage renal disease', Cell Death and Disease, vol. 12, no. 4, article no. 398, pp. 1-16. Open access 7 6 112
2020	Po'uha, ST, Le Grand, M, Brandl, MB, Gifford, AJ, Goodall, GJ, Khew-Goodall, Y & Kavallaris, M 2020, 'Stathmin levels alter PTPN14 expression and impact neuroblastoma cell migration', British Journal of Cancer, vol. 122, pp. 434-444. Open access 5 4 37
2020	Yang, J, Antin, P, Berx, G, Blanpain, C, Goodall, GJ, Khew-Goodall, Y & Sheng, G and 40 other authors and 1 consortia 2020, 'Guidelines and definitions for research on epithelial-mesenchymal transition', Nature Reviews Molecular Cell Biology, vol. 21, no. 6, pp. 341-352. Open access 857 713 126
2019	Bottini, A, Wu, DJ, Ai, R, Le Roux, M, Lonic, A, Li, X, Khew-Goodall, Y & Bottini, N 2019, 'PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes', Annals of the Rheumatic Diseases, vol. 78, no. 5, pp. 600-609. Open access 26 25 2
2018	Pillman, KA, Phillips, CA, Roslan, S, Toubia, J, Dredge, BK, Bert, AG, Lumb, R, Neumann, DP, Li, X, Conn, SJ, Liu, D, Bracken, CP, Lawrence, DM, Schreiber, AW, Khew-Goodall, Y, Goodall, GJ & Gregory, PA and 4 other authors 2018, 'miR‐200/375 control epithelial plasticity‐associated alternative splicing by repressing the RNA‐binding protein Quaking', The EMBO Journal, vol. 37, no. 13, article no. e99016, pp. 1-20. Open access 62 60 15
2015	Belle, L, Ali, N, Lonic, A, Li, X, Paltridge, JL, Roslan, S, Herrmann, D, Gehling, FK, Bert, AG, Crocker, L, Tsykin, A, Farshid, G, Goodall, GJ, Timpson, P, Daly, R & Khew-Goodall, Y 2015, 'The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking', Science Signaling, vol. 8, no. 364, article no. ra18, pp. 1-12. 51 49 18
2015	Bracken, CP, Khew-Goodall, Y & Goodall, GJ 2015, 'Network-based approaches to understand the roles of miR-200 and other microRNAs in cancer', Cancer Research, vol. 75, no. 13, pp. 2594-2599. Open access 50 50 1
2014	Bracken, CP, Li, X, Wright, JA, Lawrence, DM, Pillman, KA, Salmanidis, M, Anderson, MA, Dredge, BK, Gregory, PA, Tsykin, A, Neilsen, C, Thomson, DW, Bert, AG, Leerberg, JM, Yap, AS, Jensen, KB, Khew-Goodall, Y & Goodall, GJ 2014, 'Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion', The EMBO Journal, vol. 33, no. 18, pp. 2040-2056. Open access 116 115 13
2013	Attema, JL, Bert, AG, Lim, Y-Y, Kolesnikoff, N, Lawrence, DM, Pillman, KA, Smith, E, Drew, PA, Khew-Goodall, Y, Shannon, F & Goodall, GJ 2013, 'Identification of an enhancer that increases miR-200b~429 gene expression in breast cancer cells', PLoS One, vol. 8, no. 9, pp. 1-15. Open access 20 17 4
2013	Hauschild, N, Belle, L & Khew-Goodall, Y 2013, 'PTPN14 (protein tyrosine phosphatase, non-receptor type 14)', Atlas of Genetics and Cytogenetics in Oncology and Haematology, vol. 17, no. 7, pp. 462-466. Open access
2013	Lim, Y-Y, Wright, JA, Attema, JL, Gregory, PA, Bert, AG, Smith, E, Thomas, D, Lopez, AF, Drew, PA, Khew-Goodall, Y & Goodall, GJ 2013, 'Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem cell-like state', Journal of Cell Science, vol. 126, no. 10, pp. 2256-2266. Open access 167 154 2
2013	Paltridge, JL, Belle, L & Khew-Goodall, Y 2013, 'The secretome in cancer progression', BBA: Proteins and Proteomics, vol. 1834, no. 11, pp. 2233-2241. 97 96 6
2013	Paterson, EL, Kazenwadel, J, Bert, AG, Khew-Goodall, Y, Ruszkiewicz, A & Goodall, GJ 2013, 'Down-regulation of the miRNA-200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression', Neoplasia, vol. 15, no. 2, pp. 180-191. Open access 146 133
2011	Gregory, PA, Bracken, CP, Smith, E, Bert, AG, Wright, JA, Roslan, S, Morris, M, Wyatt, L, Farshid, G, Lim, Y-Y, Lindeman, GJ, Shannon, MF, Drew, PA, Khew-Goodall, Y & Goodall, GJ 2011, 'An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition', Molecular Biology of the Cell, vol. 22, no. 10, pp. 1686-1698. Open access 458 431
2010	Khew-Goodall, Y & Goodall, GJ 2010, 'Myc-modulated miR-9 makes more metastases', Nature Cell Biology, vol. 12, no. 3, pp. 209-211. 96 94
2008	Gregory, PA, Bert, A, Paterson, E, Barry, S, Tsykin, A, Farshid, G, Vadas, M, Khew-Goodall, Y & Goodall, G 2008, 'The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1', Nature Cell Biology, vol. 10, no. 5, pp. 593-601. 3245 3039
2008	Paterson, E, Prizzi, N, Gregory, PA, Bert, A, Khew-Goodall, Y & Goodall, G 2008, 'The microRNA-200 Family Regulates Epithelial to Mesenchymal Transition', The Scientific World Journal, vol. 8, pp. 901-904. Open access 73 69
2008	Wyatt, L & Khew-Goodall, Y 2008, 'PTP-Pez: a novel regulator of TGFβ signaling', Cell Cycle, vol. 7, no. 15, pp. 2290-2295. Open access 15 13

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Australian National University	AUSTRALIA
Cancer Council of South Australia	AUSTRALIA
Children's Cancer Institute Australia	AUSTRALIA
Flinders University	AUSTRALIA
Garvan Institute of Medical Research	AUSTRALIA
Ghent University	BELGIUM
Kumamoto University	JAPAN
La Jolla Institute for Immunology	UNITED STATES
Monash University	AUSTRALIA
SA Pathology	AUSTRALIA
University Libre Bruxelles	BELGIUM
University of Adelaide	AUSTRALIA
University of Arizona	UNITED STATES
University of California	UNITED STATES
University of California San Diego	UNITED STATES
University of Canberra	AUSTRALIA
University of Malaya	MALAYSIA
University of New South Wales	AUSTRALIA
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
Walter and Eliza Hall Institute of Medical Research	AUSTRALIA

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
110423 - Tackling Neuroblastoma using a multi-omics bioinformatics approach	Current
Investigating the role of CD47 in cancer to develop novel antitumor treatment strategies	Current
Understanding chemoresistance mechanisms in triple negative breast cancer	Current

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Professor Yeesim Khew-Goodall

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Journal Articles

External engagement & recognition

Collaborations

Collaborations

Teaching & student supervision

Courses and programs

Research degree supervision

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