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Dr Yi Long

Research Associate UniSA Clinical & Health Sciences

email Yi.Long@unisa.edu.au

Research Degree Supervisor

Research

Research focus

Medicinal and Biomolecular Chemistry
Organic Chemistry
Biochemistry and Cell Biology
Pharmacology and Pharmaceutical Sciences

Research

Outputs

Research since 2008 is shown below. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Journal Articles

Year	Output
2021	Long, Y, Yu, M, Ochnik, AM, Karanjia, JD, KC Basnet, S, Kebede, AA, Kou, L & Wang, S 2021, 'Discovery of novel 4-azaaryl-N-phenylpyrimidin-2-amine derivatives as potent and selective FLT3 inhibitors for acute myeloid leukaemia with FLT3 mutations', European Journal of Medicinal Chemistry, vol. 213, article no. 113215, pp. 1-18. 2 1
2021	Yu, M, Long, Y, Yang, Y, Li, M, Teo, T, Noll, B, Philip, S & Wang, S 2021, 'Discovery of a potent, highly selective, and orally bioavailable inhibitor of CDK8 through a structure-based optimisation', European Journal of Medicinal Chemistry, vol. 218, article no. 113391, pp. 1-23.
2021	Yu, M, Teo, T, Yang, Y, Li, M, Long, Y, Philip, S, Noll, B, Heinemann, GK, Diab, S, Eldi, P, Mekonnen, L, Anshabo, AT, Rahaman, MH, Milne, R, Hayball, JD & Wang, S 2021, 'Potent and orally bioavailable CDK8 inhibitors: design, synthesis, structure-activity relationship analysis and biological evaluation', European Journal of Medicinal Chemistry, vol. 214, pp. 1-22. 1 1
2016	Long, Y, Yu, M, Li, P, Islam, S, Goh, AW, Kumarasiri, M & Wang, S 2016, 'Synthesis and biological evaluation of heteroaryl styryl sulfone derivatives as anticancer agents', Bioorganic and Medicinal Chemistry Letters, vol. 26, no. 23, pp. 5674-5678. 7 7
2012	Li, Z, Tan, JH, He, JH, Long, Y, Ou, TM, Li, D, Gu, LQ & Huang, ZS 2012, 'Disubstituted quinazoline derivatives as a new type of highly selective ligands for telomeric G-quadruplex DNA', European Journal of Medicinal Chemistry, vol. 47, no.1, pp. 299-311. 42 40
2012	Long, Y, Li, Z, Tan, JH, Ou, TM, Li, D, Gu, LQ & Huang, ZS 2012, 'Benzofuroquinoline derivatives had remarkable improvement of their selectivity for telomeric g-quadruplex DNA over duplex DNA upon introduction of peptidyl group', Bioconjugate Chemistry, vol. 23, no. 9, pp. 1821-1831. 15 16

Research

Patents

Details	Registry	Status
Benzofuran quinoline peptide derivative as well as preparation method and application thereof as antitumor drug Huang, Z; Gu, L; Long, Yi; Li, Z	CN	Granted

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Sun Yat-Sen University	CHINA
University of South Australia	AUSTRALIA

External engagement & recognition

External engagement & recognition

Engagement/recognition	Year
Inventor & Patent Holder: China patent: CN102516355B (Peptide derivative of benzfuran quinoline and preparation method thereof and application thereof as antitumor medicament) China Patent Registry	2014
University Outstanding Graduate for Excellence Chengdu University of Traditional Chinese Medicine, China	2009

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