Location: SAHMRI, level 8, Southside, Desk number: 87
Dr. Anwar Mulugeta is a Research Associate at the Nutritional and Genetic Epidemiology Research Group. With over five years of experience as a steering committee member at the Australian Centre for Precision Health, he brings a wealth of expertise to his role. Dr. Mulugeta holds a Ph.D. in Genetic Epidemiology (awarded in 2020), an M.Pharm in Medical Pharmacology (completed in 2011), and a B.Pharm in Pharmacy (completed in 2008). He is also affiliated with the Department of Pharmacology and Clinical Pharmacy at Addis Ababa University (AAU), Ethiopia. Prior to this, he served as a Clinical Trial Coordinator for a collaborative project between AAU and Massachusetts General Hospital. Dr. Mulugeta's primary research focus lies in... Read more
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Dr. Anwar Mulugeta is a Research Associate at the Nutritional and Genetic Epidemiology Research Group. With over five years of experience as a steering committee member at the Australian Centre for Precision Health, he brings a wealth of expertise to his role. Dr. Mulugeta holds a Ph.D. in Genetic Epidemiology (awarded in 2020), an M.Pharm in Medical Pharmacology (completed in 2011), and a B.Pharm in Pharmacy (completed in 2008). He is also affiliated with the Department of Pharmacology and Clinical Pharmacy at Addis Ababa University (AAU), Ethiopia. Prior to this, he served as a Clinical Trial Coordinator for a collaborative project between AAU and Massachusetts General Hospital. Dr. Mulugeta's primary research focus lies in understanding the contributions of genetics and the environment, as well as the intricate interplay between them, in relation to disease risk. His research covers a broad spectrum of health outcomes, including cognitive impairment, dementia, depression, cancers, and various other health conditions. To accomplish this, he employs a diverse range of genetic and bioinformatic approaches, such as Mendelian randomizations, phenome-wide associations, genome-wide associations, gene-environment interactions, and machine-learning techniques.
Doctor of Philosophy University of South Australia
Master in Medical Pharmacology Addis Ababa University
Bachelor of Science (Pharmacy) Jimma University
Certificate in Fundamentals of Clinical Trials Harvard (Online)
Excludes commercial-in-confidence projects.
Open access indicates that an output is open access.
Ahmed, M, Mäkinen, VP, Lumsden, A, Boyle, T, Mulugeta, A, Lee, SH, Olver, I & Hyppönen, E 2023, 'Metabolic profile predicts incident cancer: a large-scale population study in the UK Biobank', Metabolism: Clinical and Experimental, vol. 138, article no. 155342.
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Lumsden, AL, Mulugeta, A, Makinen, V-P & Hypponen, E 2023, 'Metabolic profile-based subgroups can identify differences in brain volumes and brain iron deposition', Diabetes, Obesity and Metabolism: A Journal of Pharmacology and Therapeutics, vol. 25, no. 1, pp. 121-131.
Open access 131
Madakkatel, I, Lumsden, AL, Mulugeta, A, Olver, I & Hypponen, E 2023, 'Hypothesis-free discovery of novel cancer predictors using machine learning', European Journal of Clinical Investigation, vol. 53, no. 10, article no. e14037, pp. 1-13.
Open access 1
Pham, K, Mulugeta, A, Lumsden, A & Hyppӧnen, E 2023, 'Genetically instrumented LDL-cholesterol lowering and multiple disease outcomes: a Mendelian randomisation phenome-wide association study in the UK Biobank', British Journal of Clinical Pharmacology, vol. 89, no. 10, pp. 2992-3004.
Ahmed, M, Makinen, V-P, Mulugeta, A, Shin, J, Boyle, T, Hypponen, E & Lee, SH 2022, 'Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology', Communications Biology, vol. 5, no. 1, article no. 614, pp. 1-14.
Open access 2 1 4
Erku, D, Mersha, AG, Ali, EE, Gebretekle, GB, Wubishet, BL, Kassie, GM, Gebremichael, A, Mekonnen, AB, Eshetie, TC & Scuffham, P 2022, 'A systematic review of scope and quality of health economic evaluations conducted in Ethiopia', Health Policy and Planning, vol. 37, no. 4, pp. 514-522.
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Mulugeta, A, Eshetie, TC, Kassie, GM, Erku, D, Mekonnen, A, Lumsden, A & Hypponen, E 2022, 'Association between metabolically different adiposity subtypes and osteoarthritis: a Mendelian Randomization Study', Arthritis Care and Research, vol. 75, no. 4, pp. 885-892.
Open access 1 1 3
Mulugeta, A, Hypponen, E, Ala-Korpela, M & Makinen, V-P 2022, 'Cross-sectional metabolic subgroups and 10-year follow-up of cardiometabolic multimorbidity in the UK Biobank', Scientific Reports, vol. 12, no. 1, article no. 8590, pp. 1-11.
Open access 3 3 4
Mulugeta, A, Navale, SS, Lumsden, AL, Llewellyn, DJ & Hyppönen, E 2022, 'Healthy lifestyle, genetic risk and brain health: a gene-environment interaction study in the UK Biobank', Nutrients, vol. 14, no. 19, article no. 3907, pp. 1-13.
Open access 1 1
Navale, SS, Mulugeta, A, Zhou, A, Llewellyn, DJ & Hyppönen, E 2022, 'Vitamin D and brain health: an observational and Mendelian randomization study', American Journal of Clinical Nutrition, vol. 116, no. 2 , pp. 531-540.
Open access 23 15 1343
Pham, K, Mulugeta, A, Zhou, A, O'Brien, JT, Llewellyn, DJ & Hyppönen, E 2022, 'High coffee consumption, brain volume and risk of dementia and stroke', Nutritional Neuroscience, vol. 25, no. 10, pp. 2111-2122.
Open access 10 11 1110
Ahmed, M, Mulugeta, A, Lee, SH, Mäkinen, V-P, Boyle, T & Hyppönen, E 2021, 'Adiposity and cancer: a Mendelian randomization analysis in the UK biobank', International Journal of Obesity, vol. 45, no. 12, pp. 2657-2665.
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Challa, F, Getahun, T, Sileshi, M, Geto, Z, Kelkile, TS, Gurmessa, S, Medhin, G, Mesfin, M, Alemayehu, M, Shumet, T, Mulugeta, A, Bekele, D, Borba, CP, Oppenheim, CE, Henderson, DC, Fekadu, A, Carobene, A & Teferra, S 2021, 'Prevalence of metabolic syndrome among patients with schizophrenia in Ethiopia', BMC Psychiatry, vol. 21, no. 1, article no. 620, pp. 1-9.
Open access 6 5 1
Mulugeta, A, Lumsden, A & Hyppönen, E 2021, 'Relationship between serum 25(Oh)d and depression: causal evidence from a bi-directional mendelian randomization study', Nutrients, vol. 13, no. 1, pp. 1-13.
Open access 13 7 32
Mulugeta, A, Lumsden, A & Hyppönen, E 2021, 'Unlocking the causal link of metabolically different adiposity subtypes with brain volumes and the risks of dementia and stroke: a Mendelian randomization study', Neurobiology of Aging, vol. 102, pp. 161-169.
Open access 13 10 82
Nichols, E, Abd-Allah, F, Abdoli, A, Abosetugn, AE, Mulugeta, A & Vos, T and 205 other authors 2021, 'Global mortality from dementia: application of a new method and results from the global burden of disease study 2019', Alzheimer's and Dementia: Translational Research and Clinical Interventions, vol. 7, no. 1, article no. e12200, pp. 1-28.
Open access 47 10 9
King, C, Mulugeta, A, Nabi, F, Walton, R, Zhou, A & Hyppönen, E 2020, 'Mendelian randomization case-control PheWAS in UK Biobank shows evidence of causality for smoking intensity in 28 distinct clinical conditions', EClinicalMedicine, vol. 26, article no. 100488, pp. 1-7.
Open access 11 10 108
Lumsden, AL, Mulugeta, A, Zhou, A & Hyppönen, E 2020, 'Apolipoprotein E (APOE) genotype-associated disease risks: a phenome-wide, registry-based, case-control study utilising the UK Biobank', EBioMedicine, vol. 59, article no. 102954, pp. 1-11.
Open access 87 53 78
Mulugeta, A, Zhou, A, King, C & Hyppönen, E 2020, 'Association between major depressive disorder and multiple disease outcomes: a phenome-wide Mendelian randomisation study in the UK Biobank', Molecular Psychiatry, vol. 25, no. 7, pp. 1469-1476.
Open access 43 36 152
Nicolopoulos, K, Gebremichael, A, Zhou, A & Hypponen, E 2020, 'Association between habitual coffee consumption and multiple disease outcomes: a Mendelian randomisation phenome-wide association study in the UK Biobank', Clinical Nutrition, vol. 39, no. 11, pp. 3467-3476.
Open access 20 17 177
Rollason, V, Mouterde, M, Daali, Y, Cizkova, M, Priehodova, E, Kulichova, I, Posova, H, Petanova, J, Mulugeta, A, Makonnen, E, Al-Habsi, A, Davidson, R, Al-Balushi, KK, Al-Thihli, K, Cerna, M, Al-Yahyaee, S, Cerny, V, Yimer, G, Poloni, ES & Desmeules, J 2020, 'Safety of the Geneva cocktail, a cytochrome P450 and P-glycoprotein phenotyping cocktail, in healthy volunteers from three different geographic origins', Drug Safety, vol. 43, no. 11, pp. 1181-1189.
Open access 7 6
Hypponen, E, Mulugeta, A, Zhou, A & Santhanakrishnan, VK 2019, 'A data-driven approach for studying the role of body mass in multiple diseases: a phenome-wide registry-based case-control study in the UK Biobank', The Lancet Digital Health, vol. 1, no. 3, pp. e116-e126.
Open access 36 33 147
Mulugeta, A, Zhou, A, Vimaleswaran, KS, Dickson, C & Hypponen, E 2019, 'Depression increases the genetic susceptibility to high body mass index: evidence from UK Biobank', Depression and Anxiety, vol. 36, no. 12, pp. 1154-1162.
Open access 21 22 3
Tyrrell, J, Gebremichael, A, Wood, AR, Zhou, A, Beaumont, RN, Tuke, MA, Jones, SE, Ruth, KS, Yaghootkar, H, Sharp, S, Thompson, WD, Ji, Y, Harrison, J, Freathy, RM, Murray, A, Weedon, MN, Lewis, C, Frayling, TM & Hyppӧnen, E and 1 consortium 2019, 'Using genetics to understand the causal influence of higher BMI on depression', International Journal of Epidemiology, vol. 48, no. 3, pp. 834-848.
Open access 115 91 222
Open access 37 33 4
Bilal, A I, Tilahun, Z, Osman, ED, Mulugeta, A, Shekabdulahi, M & Berhe, DF 2017, 'Cosmetics use-related adverse events and determinants among Jigjiga town residents, Eastern Ethiopia', Dermatology and Therapy, vol. 7, no. 1, pp. 143-153.
Open access 18 17 1
Bilal, A I, Osman, ED & Mulugeta, A 2016, 'Assessment of medicines use pattern using World Health Organization's Prescribing, Patient Care and Health facility indicators in selected health facilities in eastern Ethiopia', BMC Health Services Research, vol. 16, no. 1, pp. 1-8.
Open access 49 44
Mulugeta, A, Medhin, G, Yimer, G, Jemal, R & Fekadu, A 2016, 'Quality of clinical trials for selected priority mental and neurological disorders in sub-Saharan Africa: a systematic review', Open Access Journal of Clinical Trials, vol. 8, pp. 43-52.
Open access 2
Shimels, T, Bilal, A I & Mulugeta, A 2015, 'Evaluation of Ceftriaxone utilization in internal medicine wards of general hospitals in Addis Ababa, Ethiopia: a comparative retrospective study', Journal of Pharmaceutical Policy and Practice, vol. 8, no. 1, pp. 1-8.
Open access 12 2
Borba, CP, Fekadu, A, Teferra, S, Bekele, D, Shibre, T, Oppenheim, CE, Biressaw, S, Mulugeta, A, Schoenfeld, DA & Henderson, DC 2014, 'A placebo-controlled trial of folate with B12 in patients with schizophrenia with residual symptoms in Ethiopia using a sequential parallel comparison design', British Journal of Medicine and Medical Research, vol. 4, no. 23, pp. 4090-4104.
Kiros, Y, Teklu, T, Desalegn, F, Tesfay, M, Klinkenberg, E & Mulugeta, A 2014, 'Adherence to anti-tuberculosis treatment in Tigray, Northern Ethiopia', Public Health Action, vol. 4, no. S3, pp. S31-S36.
Open access 15
Mulugeta, A & Chanie, T 2012, 'Cause of antiretroviral drug changes among patients on antiretroviral therapy at the art center in Dessei Regional Referral Hospital, Ethiopia', International Journal of Pharmaceutical Sciences and Research, vol. 3, no. 1, pp. 120-125.
Open access 3
External engagement & recognition
|Addis Ababa University||ETHIOPIA|
|Boston Medical Center||UNITED STATES|
|Boston University||UNITED STATES|
|Charles University in Prague||CZECH REPUBLIC|
|College of Medicine and Health Sciences||OMAN|
|Debre Berhan University||ETHIOPIA|
|Ethiopian Public Health Institute||ETHIOPIA|
|Federal Police Commission Health Services Directorate||ETHIOPIA|
|Harvard University||UNITED STATES|
|Horizon Health Network||CANADA|
|IRCCS Ospedale San Raffaele||ITALY|
|Jahrom University of Medical Science||IRAN|
|Jigjiga Health Sciences College||ETHIOPIA|
|King's College London||UNITED KINGDOM|
|Massachusetts General Hospital||UNITED STATES|
|Ohio State University||UNITED STATES|
|Oman Specialty Board||OMAN|
|Queen Mary University of London||UNITED KINGDOM|
|South Australian Health and Medical Research Institute (SAHMRI)||AUSTRALIA|
|Sultan Qaboos University||OMAN|
|Sultan Qaboos University Hospital||OMAN|
|Tigray Regional Health Bureau||ETHIOPIA|
|Tigray Regional Laboratory||ETHIOPIA|
|Tikur Anbesa Hospital||ETHIOPIA|
|University College London||UNITED KINGDOM|
|University of Adelaide||AUSTRALIA|
|University of Amsterdam||NETHERLANDS|
|University of Cambridge||UNITED KINGDOM|
|University of Exeter||UNITED KINGDOM|
|University of Geneva||SWITZERLAND|
|University of Newcastle||AUSTRALIA|
|University of Oulu||FINLAND|
|University of Queensland||AUSTRALIA|
|University of Reading||UNITED KINGDOM|
|University of South Australia||AUSTRALIA|
|University of Toronto||CANADA|
|University of Washington||UNITED STATES|
Supervisions from 2010 shown
|Thesis title||Student status|
|111100 - The Orexin System in depression: a potential target for pharmacological intervention||Current|
|Improving genetic prediction of ovarian cancer risk||Current|
|Lipids, statins and brain health: A large-scale study||Current|
|Predicting brain health and dementia: a machine learning approach||Current|