Professor Benjamin Thierry

Professor in Bioengineering Future Industries Institute

Mawson Lakes Campus (MM2-01K)
tel +61 8 830 23689

email benjamin.thierry@unisa.edu.au

Alternative contact

Available for media comment
Research Degree Supervisor

About me

Prof Benjamin Thierry is the University of South Australia Professor of Bioengineering and a Research Leader at the Future Industries Institute. He is a NHMRC Investigator Fellow and the Head of the South Australian Node of the ARC Centre of Excellence in Convergent Bio and Nano Science and Technology (CBNS). He received his PhD in Biomedical Engineering from McGill University in 2004 and has since received prestigious awards, including two Career Development Fellowships. He was awraded in 2020 a NHMRC Investigator Fellowships (Addressing Healthcare Disparities in Remote and Low Resource Settings with Solid-State Biodiagnostic Devices).

Prof Thierry leads the translational Bioengineering group which aims to develop and... Read more

Future Industries Institute

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About me

Prof Thierry leads the translational Bioengineering group which aims to develop and implement novel biodiagnostic and prognostic technologies and is currently involved in several clinical translation/commercialization activities. A significant outcome of his research has been the development of a patented cancer staging diagnostic technology that has received substantial commercial interest and investment through a spin-off company, Ferronova Pty Ltd. Ferronova has raised over $3.5 million in 2020 to fund several on-going clinical trials in Australia and the US. Another significant research focus is the development of biodiagnostic technologies aimed at improving prenatal care, especially in rural and low-ressource settings. In close collaboration with industry partners and clinicians, he is leading a comprehensive research program aimed at enabling better detection and treatment of pregnancy complications such as preeclampsia and pre-term birth. He co-founded SanguisDx in 2020 to accelerate the development of his solid-state diagnostic platform. He has also developed and patented a technology aimed at enabling comprehensive non-invasive prenatal genetic testing, which is currently being developed through a NHMRC Development Grant.

With the support of the ARC Centre of Excellence in Convergent Bio and Nano Science, Prof Thierry leads a research program oaimed at the development of next-generation in vitro organ and disease models, including models based on "organs-on-chips" concept and 3D Bioprinting. A specific focus is on patients derived tumour-on-chip models that recapitulate the tumour microenvironment. These models are being used to assist in the development of better cancer therapeutics, including based on ionizing radiation and immunotherapy.

Research

Research focus

Chemical Sciences
Biological Sciences
Engineering
Biomedical Engineering
Chemical Engineering

Highlights

The Bioengineering group aims at bridging the gap between engineering and medicine, with specific focus on oncology and prenatal diagnostics. To this end, we are developing a range of technologies aimed at providing either basic insights about biological processes or designed to address significant biomedical challenges. More info can be find on our web site: www.bionanoengineering.com.

Current research areas:

"Intraoperative cancer staging": Ferronova ltd pty has been spun off to develop and commercialize our cancer staging technology. The company is based at the Future Industries Institute and active;y collaborate with the University of Sydney, the Univerity of New South Wales, the Royal Adelaide Hospital and the MD Anderson Cancer... Read more

Research

Projects

Excludes commercial-in-confidence projects.

CRC P: Nanoparticle manufacturing and its application in brain cancer radiotherapy, CRC-P, 09/01/2023 - 09/06/2026
Preclinical validation of a new molecular magnetic resonance imaging of glioblastoma towards improved image-guided treatment, Tour de Cure Ltd, 01/07/2023 - 01/07/2024
Point of Care Testing for Preeclampsia Towards Improving Antenatal Care in Rural Australia, The Hospital Research Foundation, 01/02/2022 - 31/01/2024
Development of Superior Sentinel Lymph Node Mapping Procedures using Magnetic Tracers, NHMRC - Development Grant, 01/01/2019 - 30/09/2022
FAPi-MRI towards Better target delineation of high-grade Gliomas, Neurosurgical Research Foundation, 30/08/2021 - 31/08/2022
AAS - Portable Healthcare: High-Value Micro/Nano-Scale Structures and Coating for Mass Production of Biomedical Devices, Australian Academy of Science, 01/11/2017 - 28/02/2022
Detection and viability of waterborne pathogens using a gut-on-chip, ARC - Linkage Project, 12/12/2018 - 11/12/2021
Preoperative Imaging of Metastatic Deposits in Regional Lymph Nodes: Preclinical Validation of a New Staging Modality for Head and Neck Cancer, NHMRC - Project Grant, 01/01/2019 - 31/07/2021
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, ARC - Centre of Excellence, 01/04/2014 - 29/06/2021
Nanoscale silicon field-effect transistor diagnostic technology, ARC - Discovery Projects, 27/03/2017 - 31/12/2020
Development of Superior Sentinel Lymph Node Staging Procedures in Head and Neck Cancer Using Magnetic Tracers, Garnett Passe & Rodney Williams Memorial Foundation-Conjoint Grant, 01/06/2018 - 31/05/2020
Targeting particulate carriers to epithelial M cells, ARC - Linkage Project, 15/12/2015 - 30/09/2019
Advanced technologies for improved molecular diagnostic and prognostic of gastrointestinal cancers, NHMRC - Career Development Fellowship, 01/01/2015 - 31/12/2018
Nanomedicines Immunotargeting: Hitting the Target or Lost In Translation?, NHMRC - Project Grant, 01/01/2013 - 31/12/2016
NHMRC Equip 2015 - Stage-top incubator for live-cell imaging with the Zeiss LSM 710 super-high resolution microscope, NHMRC - Equipment Only Grants, 01/01/2016 - 31/12/2016
A novel nitric oxide-based treatment for recalcitrant Staphylococcus aureus-associated chronic rhinosinusitis (admin by Uni of Adelaide), NHMRC - Project Grant, 01/01/2013 - 30/06/2016

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID, ResearcherID or Scopus

Open access indicates that an output is open access.

Highlights

Year	Output
2019	Delon, LC, Guo, Z, Oszmiana, A, Chien, CC, Gibson, R, Prestidge, C & Thierry, B 2019, 'A systematic investigation of the effect of the fluid shear stress on Caco-2 cells towards the optimization of epithelial organ-on-chip models', Biomaterials, vol. 225, Article number 119521 pp. 1-11. 76 66 2
2019	Guo, Z, Yang, C-T, Maritz, MF, Wu, H, Wilson, P, Warkiani, ME, Chien, C-C, Kempson, I, Aref, AR & Thierry, B 2019, 'Validation of a vasculogenesis microfluidic model for radiobiological studies of the human microvasculature', Advanced Materials Technologies, vol. 4, no. 4 article no. 1800726, pp. 1-12. 17 15 58
2019	Rezaei, M, Winter, M, Zander-Fox, D, Whitehead, C, Liebelt, J, Warkiani, ME, Hardy, T & Thierry, B 2019, 'A reappraisal of circulating fetal cell noninvasive prenatal testing', Trends in Biotechnology, vol. 37, no. 6, pp. 632-644. Open access 19 16 2
2019	Tran, DP, Winter, M, Yang, C-T, Stockmann, R, Offenhausser, A & Thierry, B 2019, 'Silicon nanowires field effect transistors: a comparative sensing performance between electrical impedance and potentiometric measurement paradigms', Analytical Chemistry, vol. 91, no. 19, pp. 12568-12573. Open access 15 11 1
2016	Duy Tran, Winter, M, Wolfrum, B, Stockmann, R, Yang, C-T, Pourhassan-Moghaddam, M, Offenhaüsser, A & Thierry, B 2016, 'Toward intraoperative detection of disseminated tumor cells in lymph nodes with silicon nanowire field effect transistors', ACS Nano, vol. 10, no. 2, pp. 2357-2364. Open access 50 46 54

Chapters

Year	Output
2012	Thierry, B, Ma, D & Winnik, FM 2012, 'The design of polysaccharide multilayers for medical applications', in G Decher & JB Schlenoff (eds), Multilayer thin films: sequential assembly of nanocomposite materials, 2nd ed., Wiley-Blackwell, Germany, ch. 26, pp. 637-658. 1
2011	Thierry, B & Majewski, PJ 2011, 'Superparamagnetic Magnetite Nanoparticles', in HS Nalwa (ed.), Encyclopedia of Nanoscience and Nanotechnology, ASP - American Scientific Publishers, USA, vol. 23, pp. 533-544.
2009	Majewski, P & Thierry, B 2009, 'Functionalized magnetite nanoparticles-synthesis, properties, and bioapplications', in W Sigmund et al. (eds), Particulate systems in nano and biotechnologies, CRC Press, USA, ch. 15, pp. 331-352. 3

Journal Articles

Year	Output
2023	Cousins, A, Krishnan, S, Krishnan, G, Pham, N, Milanova, V, Nelson, M, Shetty, A, Ikoma, N & Thierry, B 2023, 'Preclinical evaluation of sentinel node localization in the stomach via mannose-labelled magnetic nanoparticles and indocyanine green', Surgical Endoscopy, vol. 37, no. 8, pp. 6185-6196. Open access
2023	Dehghankelishadi, P, Badiee, P, Maritz, MF, Dmochowska, N & Thierry, B 2023, 'Bosutinib high density lipoprotein nanoformulation has potent tumour radiosensitisation effects', Journal of Nanobiotechnology, vol. 21, article no. 102, pp. 1-14. Open access 2
2023	Dmochowska, N, Milanova, V, Mukkamala, R, Keung Chow, K, Pham, NT, Srinivasarao, M, Ebert, LM, Stait Gardner, T, Le, H, Shetty, A, Nelson, M, Low, PS & Thierry, B 2023, 'Nanoparticles targeted to fibroblast activation protein outperform PSMA for MRI delineation of primary prostate tumors', Small, vol. 19, no. 21, article no. 2204956. Open access 1 1
2023	Hou, J, Qian, X, Xu, Y, Guo, Z, Thierry, B, Yang, CT, Zhou, X & Mao, C 2023, 'Rapid and reliable ultrasensitive detection of pathogenic H9N2 viruses through virus-binding phage nanofibers decorated with gold nanoparticles', Biosensors and Bioelectronics, vol. 237, article no. 115423.
2023	Jia, Z, Wignall, A, Delon, L, Guo, Z, Prestidge, C & Thierry, B 2023, 'An ex vivo model enables systematic investigation of the intestinal absorption and transcytosis of oral particulate nanocarriers', ACS Biomaterial Science and Engineering, vol. 9, no. 6, pp. 2857-2867. Open access 3 3
2022	Alizadeh-Ghodsi, M, Owen, KL, Townley, SL, Zanker, D, Toubia, J, Gargett, T, Thierry, B & Selth, LA and 17 other authors 2022, 'Potent stimulation of the androgen receptor instigates a viral mimicry response in prostate cancer', Cancer Research Communications, vol. 2, no. 7, pp. 706-724. Open access 15
2022	Amen, MT, Pham, TTT, Cheah, E, Duy Tran & Thierry, B 2022, 'Metal-oxide FET biosensor for point-of-care testing: overview and perspective', Molecules, vol. 27, no. 2, article no. 7952, pp. 1-24. Open access 2 1 1
2022	Badiee, P, Maritz, MF & Thierry, B 2022, 'Glycogen kinase 3 inhibitor nanoformulation as an alternative strategy to inhibit PD-1 immune checkpoint', International Journal of Pharmaceutics, vol. 622, article no. 121845. 3 3
2022	Badiee, P, Maritz, MF, Dmochowska, N, Cheah, E & Thierry, B 2022, 'Intratumoral anti-PD-1 nanoformulation improves its biodistribution', ACS Applied Materials and Interfaces, vol. 14, no. 14, pp. 15881-15893. 1 6
2022	Cheah, E, Tran, DP, Amen, MT, Arrua, RD, Hilder, EF & Thierry, B 2022, 'Integrated platform addressing the finger-prick blood processing challenges of point-of-care electrical biomarker testing', Analytical Chemistry, vol. 94, no. 2, pp. 1256-1263. Open access 3 3 2
2022	Dalziell, J, Keaney, J, Kearnes, M, Thierry, B & Winter, M 2022, 'Bioengineering human placentas: social implications of an advancing field', Trends in Biotechnology, vol. 40, no. 2, pp. 137-140. Open access 7
2022	Dehghankelishadi, P, Maritz, MF, Badiee, P & Thierry, B 2022, 'High density lipoprotein nanoparticle as delivery system for radio-sensitising miRNA: an investigation in 2D/3D head and neck cancer models', International Journal of Pharmaceutics, vol. 617, article no. 121585. 5 3 1
2022	Dehghankelishadi, P, Maritz, MF, Dmochowska, N, Badiee, P, Cheah, E, Kempson, I, Berbeco, R I & Thierry, B 2022, 'Formulation of simvastatin within high density lipoprotein enables potent tumour radiosensitisation', Journal of Controlled Release, vol. 346, pp. 98-109. 6 1 4
2022	Delon, L, Gibson, RJ, Prestidge, CA & Thierry, B 2022, 'Mechanisms of uptake and transport of particulate formulations in the small intestine', Journal of Controlled Release, vol. 343, pp. 584-599. Open access 11 6 5
2022	Delon, LC, Faria, M, Jia, Z, Johnston, S, Gibson, R, Prestidge, CA & Thierry, B 2022, 'Capturing and quantifying particle transcytosis with microphysiological intestine-on-chip models', Small Methods, vol. 7, no. 1, article no. 2200989, pp. 1-12. Open access
2022	Elsemary, MT, Maritz, MF, Smith, LE, Warkiani, M, Bandara, V, Napoli, S, Barry, SC, Coombs, JT & Thierry, B 2022, 'Inertial microfluidic purification of CAR-T-Cell products', Advanced Biology, vol. 6, no. 1, article no. 2101018, pp. 1-12. 2 1 1
2022	Guo, Z, Yang, C-T, Chien, C-C, Selth, LA, Bagnaninchi, PO & Thierry, B 2022, 'Optical cellular micromotion: a new paradigm to measure tumor cells invasion within gels mimicking the 3D tumor environments', Small Methods, vol. 6, no. 8, article no. 2200471. Open access 2 1
2022	Howard, D, Turnbull, T, Paterson, DJ, Thierry, B & Kempson, I 2022, 'Cell size as a primary determinant in targeted nanoparticle uptake', ACS Applied Bio Materials, vol. 5, no. 9, 4222-4231. 2
2022	Krishnan, G, Cousins, A, Pham, N, Milanova, V, Nelson, M, Krishnan, S, Shetty, A, van den Berg, N, Rosenthal, E, Krishnan, S, Wormald, P-J, Foreman, A & Thierry, B 2022, 'Preclinical evaluation of a mannose-labeled magnetic tracer for enhanced sentinel lymph node retention in the head and neck', Nanomedicine: Nanotechnology Biology and Medicine, vol. 42, pp. 1-11. Open access 6 6 1
2022	Krishnan, G, Cousins, A, Pham, N, Milanova, V, Nelson, M, Krishnan, S, van den Berg, NS, Shetty, A, Rosenthal, EL, Wormald, P-J, Thierry, B, Foreman, A & Krishnan, S 2022, 'Preclinical feasibility of robot-assisted sentinel lymph node biopsy using multi-modality magnetic and fluorescence guidance in the head and neck', Head and Neck, vol. 44, no. 12, pp. 2696-2707. Open access 1 1 1
2022	Li, X, Liu, L, Whitehead, C, Li, J, Thierry, B, Le, TD & Winter, M 2022, 'Identifying preeclampsia-associated genes using a control theory method', Briefings in Functional Genomics, vol. 21, no. 4, pp. 296-309. Open access 1
2022	Pham, QN, Winter, M, Milanova, V, Young, C, Condina, MR, Hoffmann, P, Pham, NT, Tung, TT, Losic, D & Thierry, B 2022, 'Magnetic enrichment of immuno-specific extracellular vesicles for mass spectrometry using biofilm-derived iron oxide nanowires', Nanoscale, vol. 15, no. 3, pp. 1236-1247. 1 1 1
2022	Razavi Bazaz, S, Mihandust, A, Salomon, R, Joushani, HAN, Li, W, Amiri, HA, Mirakhorli, F, Zhand, S, Shrestha, J, Miansari, M, Thierry, B, Jin, D & Ebrahimi Warkiani, M 2022, 'Zigzag microchannel for rigid inertial separation and enrichment (Z-RISE) of cells and particles', Lab on A Chip: Miniaturisation for Chemistry, Physics, Biology, Materials Science and Bioengineering, vol. 22, no. 21, pp. 4093-4109. 14 8 10
2021	Hou, J, Shen, J, Zhao, N, Yang, CT, Thierry, B, Zhou, X, Zhu, J & Mao, C 2021, 'Detection of a single circulating tumor cell using a genetically engineered antibody-like phage nanofiber probe', Materials Today Advances, vol. 12, article no. 100168. Open access 7 6
2021	Jia, Z, Guo, Z, Yang, CT, Prestidge, C & Thierry, B 2021, ''Mucus-on-chip': a new tool to study the dynamic penetration of nanoparticulate drug carriers into mucus', International Journal of Pharmaceutics, vol. 598, article no. 120391, pp. 1-9. Open access 13 11
2021	Jia, Z, Wignall, A, Prestidge, C & Thierry, B 2021, 'An ex vivo investigation of the intestinal uptake and translocation of nanoparticles targeted to Peyer's patches microfold cells', International Journal of Pharmaceutics, vol. 594, article no. 120167, pp. 1-7. Open access 6 4
2021	Ni, C, Shen, Y, Li, Z, Yang, CT, Thierry, B, Yang, B & Zhou, X 2021, 'An ultrasensitive virus ELISA based on a magnetic mesoporous silica nanoprobe', Particle and Particle Systems Characterization, vol. 38, no. 11, article no. 2100146.
2021	Pham, TTT, Tran, PD, Nguyen, MC, Amen, MT, Winter, M, Whitehead, C, Toh, J & Thierry, B 2021, 'A simplified point-of-care testing approach for preeclampsia blood biomarkers based on nanoscale field effect transistors', Nanoscale, vol. 13, no. 28, pp. 12279-12287. Open access 5 5 7
2021	Rezaei, M, Radfar, P, Winter, M, McClements, L, Thierry, B & Warkiani, ME 2021, 'Simple-to-operate approach for single cell analysis using a hydrophobic surface and nanosized droplets', Analytical Chemistry, vol. 93, no. 10, pp. 4584-4592. Open access 13 9 4
2021	Winter, M, Jankovic-Karasoulos, T, Roberts, CT, Bianco-Miotto, T & Thierry, B 2021, 'Bioengineered microphysiological placental models: towards improving understanding of pregnancy health and disease', Trends in Biotechnology, vol. 39, no. 11, pp. 1221-1235. Open access 7 6 6
2021	Xu, H, Shen, J, Yang, C, Thierry, B, Zhu, Y, Mao, C & Zhou, X 2021, 'Naked-eye counting of pathogenic viruses by phage-gold nanobiomaterials as probes', Materials Today Advances, vol. 10, article no. 100122, pp. 1-6. Open access 7 4
2020	Chen, F, Di, T, Yang, C-T, Zhang, T, Thierry, B & Zhou, X 2020, 'Naked-eye enumeration of single chlamydia pneumoniae based on light scattering of gold nanoparticle probe', ACS Sensors, vol. 5, no. 4, pp. 1140-1148. 7 7 1
2020	Delon, LC, Guo, Z, Kashani, MN, Yang, CT, Prestidge, C & Thierry, B 2020, 'Hele Shaw microfluidic device: a new tool for systematic investigation into the effect of the fluid shear stress for organs-on-chips', MethodsX, vol 7, article no. 100980, pp. 1-17. Open access 3 2
2020	Delon, LC, Nilghaz, A, Cheah, E, Prestidge, C & Thierry, B 2020, 'Unlocking the potential of organ-on-chip models through pumpless and tubeless microfluidics', Advanced Healthcare Materials, vol. 9, no. 11, article no. 1901784, pp. 1-9. Open access 17 11 2
2020	Dong, D, Thomas, N, Ramezanpour, M, Psaltis, AJ, Huang, S, Zhao, Y, Thierry, B, Wormald, PJ, Prestidge, CA & Vreugde, S 2020, 'Inhibition of Staphylococcus aureus and Pseudomonas aeruginosa biofilms by quatsomes in low concentrations', Experimental Biology and Medicine, vol. 245, no. 1, pp. 34-41. Open access 13 12 2
2020	Gloag, L, Mehdipour, M, Ulanova, M, Mariandry, K, Nichol, MA, Hernandez-Castillo, DJ, Gaudet, J, Qiao, R, Zhang, J, Nelson, M, Thierry, B, Alvarez-Lemus, MA, Tan, TT, Gooding, JJ, Braidy, N, Sachdev, PS & Tilley, RD 2020, 'Zero valent iron core-iron oxide shell nanoparticles as small magnetic particle imaging tracers', Chemical Communications, vol. 56, no. 24, pp. 3504-3507. 16 16 3
2020	Gunasekera, S, Zahedi, A, O'dea, M, King, B, Monis, P, Thierry, B, Carr, JM & Ryan, U 2020, 'Organoids and bioengineered intestinal models: potential solutions to the Cryptosporidium culturing dilemma', Microorganisms, vol. 8, no. 5, article no. 715, pp. 1-16. Open access 18 14 4
2020	Howard, D, Sebastian, S, Le, QVC, Thierry, B & Kempson, I 2020, 'Chemical mechanisms of nanoparticle radiosensitization and radioprotection: A review of structure-function relationships influencing reactive oxygen species', International Journal of Molecular Sciences, vol. 21, no. 2, pp. 1-23. Open access 60 51 1
2020	Shrestha, J, Razavi Bazaz, S, Aboulkheyr Es, H, Yaghobian Azari, D, Thierry, B, Ebrahimi Warkiani, M & Ghadiri, M 2020, 'Lung-on-a-chip: the future of respiratory disease models and pharmacological studies', Critical Reviews in Biotechnology, vol. 40, no. 2, pp. 213-230. Open access 87 79 4
2019	Delon, LC, Guo, Z, Oszmiana, A, Chien, CC, Gibson, R, Prestidge, C & Thierry, B 2019, 'A systematic investigation of the effect of the fluid shear stress on Caco-2 cells towards the optimization of epithelial organ-on-chip models', Biomaterials, vol. 225, Article number 119521 pp. 1-11. 76 66 2
2019	Guo, Z, Yang, C-T, Maritz, MF, Wu, H, Wilson, P, Warkiani, ME, Chien, C-C, Kempson, I, Aref, AR & Thierry, B 2019, 'Validation of a vasculogenesis microfluidic model for radiobiological studies of the human microvasculature', Advanced Materials Technologies, vol. 4, no. 4 article no. 1800726, pp. 1-12. 17 15 58
2019	Klisuric, A, Thierry, B, Delon, L, Prestidge, CA & Gibson, RJ 2019, 'Identifying human and murine M cells in vitro', Experimental Biology and Medicine, vol. 244, no. 7, pp. 554-564. Open access 4 3 4
2019	Pocock, K, Delon, LC, Khatri, A, Prestidge, C, Gibson, R, Barbe, C & Thierry, B 2019, 'Uptake of silica particulate drug carriers in an intestine-on-a-chip: towards a better in vitro model of nanoparticulate carrier and mucus interactions', Biomaterials Science, vol. 7, pp. 2410-2420. 24 21
2019	Rezaei, M, Winter, M, Zander-Fox, D, Whitehead, C, Liebelt, J, Warkiani, ME, Hardy, T & Thierry, B 2019, 'A reappraisal of circulating fetal cell noninvasive prenatal testing', Trends in Biotechnology, vol. 37, no. 6, pp. 632-644. Open access 19 16 2
2019	Thuy, TTP, Tran, D P & Thierry, B 2019, 'High performance indium oxide nanoribbon FETs: mitigating devices signal variation from batch fabrication', Nanoscale Advances, vol. 1, no. 12, pp. 4870-4877. Open access 6 6 4
2019	Tran, DP, Winter, M, Yang, C-T, Stockmann, R, Offenhausser, A & Thierry, B 2019, 'Silicon nanowires field effect transistors: a comparative sensing performance between electrical impedance and potentiometric measurement paradigms', Analytical Chemistry, vol. 91, no. 19, pp. 12568-12573. Open access 15 11 1
2019	Turnbull, T, Douglass, M, Williamson, NH, Howard, D, Bhardwaj, R, Lawrence, M, Paterson, DJ, Bezak, E, Thierry, B & Kempson, IM 2019, 'Cross-correlative single-cell analysis reveals biological mechanisms of nanoparticle radiosensitization', ACS Nano, vol. 13, no. 5, pp. 5077-5090. Open access 41 40 3
2019	Turnbull, T, Thierry, B & Kempson, I 2019, 'A quantitative study of intercellular heterogeneity in gold nanoparticle uptake across multiple cell lines', Analytical and Bioanalytical Chemistry, vol. 411, no. 28, pp. 7529-7538. 14 11 1
2019	Vu, V-P, Tran, Q-T, Pham, D-T, Tran, P-D, Thierry, B, Chu, T-X & Mai, A-T 2019, 'Possible detection of antibiotic residue using molecularly imprinted polyaniline‐based sensor', Vietnam Journal of Chemistry, vol. 57, no.3, pp. 328-333. Open access 11
2019	Winter, M, Cai, Z, Winkler, K, Georgiou, K, Inglis, D, Lavranos, T, Rezaei, M, Warkiani, M & Thierry, B 2019, 'Circulating tumour cell RNA characterisation from colorectal cancer patient blood after inertial microfluidic enrichment', MethodsX, vol. 6, pp. 1512-1520. Open access 8 7 3
2019	Zhou, X, Yang, C-T, Xu, Q, Lou, Z, Xu, Z, Thierry, B & Gu, N 2019, 'Gold nanoparticle probe-assisted antigen-counting chip using SEM', ACS Applied Materials and Interfaces, vol. 11, no. 7, pp 6769-6776. 9 8 7
2018	Chen, F, Tang, F, Yang, CT, Zhao, X, Wang, J, Thierry, B, Bansal, V, Dai, J & Zhou, X 2018, 'Fast and highly sensitive detection of pathogens wreathed with magnetic nanoparticles using dark-field microscopy', ACS Sensors, vol. 3, no. 10, pp. 2175-2181. Open access 15 15 1
2018	Cousins, A, Tsopelas, C, Balalis, G, Thompson, SK, Bartholomeusz, D, Wedding, AB & Thierry, B 2018, 'Hybrid ⁹⁹m-Tc-magnetite tracer for dual modality sentinel lymph node mapping', Journal of Materials Science: Materials in Medicine, vol. 29, no. 6, article no. 76, pp. 1-11. Open access 2 3
2018	Diéguez, L, Winter, M, Molan, S, Monis, P, King, B & Thierry, B 2018, 'Disposable microfluidic micromixers for effective capture of Cryptosporidium parvum oocysts from water samples', Journal of Biological Engineering, vol. 12, no. 1, article no. 4, pp. 1-8. Open access 5 3
2018	Hasan, S, Albayaty, YN, Thierry, B, Prestidge, CA & Thomas, N 2018, 'Mechanistic studies of the antibiofilm activity and synergy with antibiotics of isosorbide mononitrate', European Journal of Pharmaceutical Sciences, vol. 115, pp. 50-56. 5 3 1
2018	Tran, DP, Pham, TTT, Wolfrum, B, Offenhäusser, A & Thierry, B 2018, 'CMOS-compatible silicon nanowire field-effect transistor biosensor: technology development toward commercialization', Materials, vol. 11, no. 5, article no. 785, pp. 1-26. Open access 77 60 14
2018	Winter, M, Hardy, T, Rezaei, M, Nguyen, V, Zander-Fox, D, Warkiani, ME & Thierry, B 2018, 'Isolation of circulating fetal trophoblasts using inertial microfluidics for noninvasive prenatal testing', Advanced Materials Technologies, vol. 3, no. 7, article no. 1800066 , pp. 1-10. Open access 30 28 63
2017	Hasan, S, Thomas, N, Thierry, B & Prestidge, CA 2017, 'Biodegradable nitric oxide precursor-loaded micro- and nanoparticles for the treatment of Staphylococcus aureus biofilms', Journal of Materials Chemistry B, vol. 5, pp. 1005-1014. Open access 22 22
2017	Hasan, S, Thomas, N, Thierry, B & Prestidge, CA 2017, 'Controlled and localized nitric oxide precursor delivery from chitosan gels to staphylococcus aureus biofilms', Journal of Pharmaceutical Sciences, vol. 106, no. 12, pp. 3556-3563. 9 8 1
2017	Pai, J-H, Yang, C-T, Hsu, HY, Wedding, AB & Thierry, B 2017, 'Development of a simplified approach for the fabrication of localised surface plasmon resonance sensors based on gold nanorods functionalized using mixed polyethylene glycol layers', Analytica Chimica Acta, vol. 974, pp. 87-92. 25 21
2017	Pocock, K, Delon, L, Bala, V, Rao, S, Priest, C, Prestidge, C & Thierry, B 2017, 'Intestine-on-a-chip microfluidic model for efficient in vitro screening of oral chemotherapeutic uptake', ACS Biomaterial Science and Engineering, vol. 3, no. 6, pp. 951-959. 69 67
2017	Turnbull, T, Douglass, M, Bezak, E, Thierry, B & Kempson, I 2017, 'An image processing application for quantitative cross-correlative microscopy for large cell-populations: a gold nanoparticle radiosensitisation study', Powder Diffraction, vol. 32, no. S2, pp. S33-S37. Open access 1 1
2017	Yang, C-T, Pourhassan-Moghaddam, M, Wu, L, Bai, P & Thierry, B 2017, 'Ultrasensitive detection of cancer prognostic miRNA biomarkers based on surface plasmon enhanced light scattering', ACS Sensors, vol. 2, no. 5, pp. 635-640. 38 34
2016	Duy Tran, Winter, M, Wolfrum, B, Stockmann, R, Yang, C-T, Pourhassan-Moghaddam, M, Offenhaüsser, A & Thierry, B 2016, 'Toward intraoperative detection of disseminated tumor cells in lymph nodes with silicon nanowire field effect transistors', ACS Nano, vol. 10, no. 2, pp. 2357-2364. Open access 50 46 54
2016	Fong, W-K, Hanley, TL, Thierry, B, Hawley, A, Boyd, BJ & Landersdorfer, CB 2016, 'External manipulation of nanostructure in photoresponsive lipid depot matrix to control and predict drug release in vivo', Journal of Controlled Release, vol. 228, pp. 67-73. 30 28 1
2016	Hasan, S, Thomas, N, Thierry, B, Vreugde, S, Wormald, P-J & Prestidge, CA 2016, 'Recent trends on the use of nanoparticles for nitric oxide delivery in antimicrobial applications', Drug Delivery Letters, vol. 6, no. 1, pp. 3-10. 2
2016	Pelttari, L, Khan, S, Vuorela, M, Kiiski, J, Thierry, B & Zeps, N and 349 other authors 2016, 'RAD51B in familial breast cancer', PLoS One, vol. 11, no. 5, article no. e0153788, pp. 1-18. Open access 19 19 3
2016	Pocock, KJ, Gao, X, Wang, C, Priest, C, Prestidge, CA, Mawatari, K, Kitamori, T & Thierry, B 2016, 'Low-temperature bonding process for the fabrication of hybrid glass-membrane organ-on-a-chip devices', Journal of Micro/ Nanolithography, MEMS, and MOEMS, vol. 15, no. 4, pp. 1-9. 8 5
2016	Thomas, N, Thorn, C, Richter, K, Thierry, B & Prestidge, C 2016, 'Efficacy of poly-lactic-co-glycolic acid micro- and nanoparticles of ciprofloxacin against bacterial biofilms', Journal of Pharmaceutical Sciences, vol. 105, no. 10, pp.3115-3122. Open access 38 36 2
2016	Yang, C-T, Wu, L, Bai, P & Thierry, B 2016, 'Investigation of plasmonic signal enhancement based on long range surface plasmon resonance with gold nanoparticle tags', Journal of Materials Chemistry C, vol. 4, no. 41, pp. 9897-9904. 25 25 4
2016	Yang, C-T, Wu, L, Liu, X, Tran, NT, Bai, P, Liedberg, B, Wang, Y & Thierry, B 2016, 'Exploiting surface-plasmon-enhanced light scattering for the design of ultrasensitive biosensing modality', Analytical Chemistry, vol. 88, no. 23, pp. 11924-11930. 25 22
2015	Cousins, A, Balalis, G, Thompson, S, Morales, DF, Mohtar, A, Wedding, A & Thierry, B 2015, 'Novel handheld magnetometer probe based on magnetic tunnelling junction sensors for intraoperative sentinel lymph node identification', Scientific Reports, vol. 5, article no. 10842, pp. 1-10. Open access 23 22
2015	Diéguez, LM, Winter, MA, Pocock, KJ, Bremmell, KE & Thierry, B 2015, 'Efficient microfluidic negative enrichment of circulating tumor cells in blood using roughened PDMS', The Analyst, vol. 140, no. 10, pp. 3365-3372. Open access 46 42 3
2015	Dong, D, Thomas, N, Thierry, B, Vreugde, S, Prestidge, CA & Wormald, P-J 2015, 'Distribution and inhibition of liposomes on staphylococcus aureus and pseudomonas aeruginosa biofilm', PLoS One, vol. 10, no. 6, article no. e0131806, pp. 1-16. Open access 61 58 14
2015	Hardingham, JE, Grover, P, Winter, M, Hewett, PJ, Price, TJ & Thierry, B 2015, 'Detection and clinical significance of circulating tumor cells in colorectal cancer: 20 years of progress', Molecular Medicine, vol. 21, pp. S21-S25. Open access 110 98
2015	Ho, TT, Bremmell, KE, Krasowska, M, Stringer, DN, Thierry, B & Beattie, DA 2015, 'Tuning polyelectrolyte multilayer structure by exploiting natural variation in fucoidan chemistry', Soft Matter, vol. 11, no. 11, pp. 2110-2124. 35 31 9
2015	Jardeleza, C, Thierry, B, Rao, S, Rajiv, S, Drilling, A, Miljkovic, D, Paramasivan, S, James, C, Dong, D, Thomas, N, Vreugde, S, Prestidge, CA & Wormald, P-J 2015, 'An in vivo safety and efficacy demonstration of a topical liposomal nitric oxide donor treatment for Staphylococcus aureus biofilm-associated rhinosinusitis', Translational Research: The Journal of Laboratory and Clinical Medicine, vol. 166, no. 6, pp. 683-692. Open access 23 23 1
2015	Sobral Leite, M, Wesseling, J, Smit, VT, Nevanlinna, H, Schmidt, MK & Thierry, B and 40 other authors and 1 consortia (claiming author is part of consortia 2015, 'Annexin A1 expression in a pooled breast cancer series: association with tumor subtypes and prognosis', BMC Medicine, vol. 13, no. 1, article no. 156, pp. 1-11. Open access 45 42
2015	Thomas, N, Dong, D, Richter, K, Ramezanpour, M, Vreugde, S, Thierry, B, Wormald, P-J & Prestidge, CA 2015, 'Quatsomes for the treatment of Staphylococcus aureus biofilm', Journal of Materials Chemistry B, vol. 3, no. 14, pp. 2770-2777. 24 22
2015	Turnbull, T, Douglass, M, Paterson, D, Bezak, E, Thierry, B & Kempson, I 2015, 'Relating intercellular variability in nanoparticle uptake with biological consequence: a quantitative x-ray fluorescence study for radiosensitization of cells', Analytical Chemistry, vol. 87, no. 21, pp. 10693-10697. 14 12
2015	Winter, M, Gibson, R, Ruszkiewicz, A, Thompson, SK & Thierry, B 2015, 'Beyond conventional pathology: towards preoperative and intraoperative lymph node staging', International Journal of Cancer, vol. 136, no. 4, pp. 743-751. Open access 9 10 3
2014	Cousins, A, Thompson, SK, Wedding, AB & Thierry, B 2014, 'Clinical relevance of novel imaging technologies for sentinel lymph node identification and staging', Biotechnology Advances, vol. 32, no. 2, pp. 269-279. 48 47 1
2014	Duy Tran, Macdonald, TJ, Wolfrum, B, Stockmann, R, Nann, T, Offenhäusser, A & Thierry, B 2014, 'Photoresponsive properties of ultrathin silicon nanowires', Applied Physics Letters, vol. 105, no. 23, article no. 231116, pp. 1- 5. 21 20
2014	Duy Tran, Wolfrum, B, Stockmann, R, Offenhaüsser, A & Thierry, B 2014, 'Fabrication of locally thinned down silicon nanowires', Journal of Materials Chemistry C, vol. 2, no. 26, pp. 5229-5234. Open access 13 11
2014	Duy Tran, Wolfrum, B, Stockmann, R, Pai, J-H, Pourhassan-Moghaddam, M, Offenhaüsser, A & Thierry, B 2014, 'Complementary metal oxide semiconductor compatible silicon nanowires-on-a-chip: fabrication and preclinical validation for the detection of a cancer prognostic protein marker in serum', Analytical Chemistry, vol. 87, no. 3, pp. 1662-1668. 26 22 1
2014	Fong, W-K, Hanley, TL, Thierry, B, Tilley, A, Kirby, N, Waddington, LJ & Boyd, BJ 2014, 'Understanding the photothermal heating effect in non-lamellar liquid crystalline systems, and the design of new mixed lipid systems for photothermal on-demand drug delivery', Physical Chemistry Chemical Physics, vol. 16, no. 45, pp. 24936-24953. 27 26
2014	Jardeleza, C, Rao, S, Thierry, B, Gajjar, P, Vreugde, S, Prestidge, CA & Wormald, P-J 2014, 'Liposome-encapsulated ISMN: a novel nitric oxide-based therapeutic agent against Staphylococcus aureus biofilms', PLoS One, vol. 9 no. 3, article no. e92117, pp. 1-9. Open access 35 31 1
2014	Kempson, I, Smith, E, Gao, M, de Jonge, M & Thierry, B 2014, 'Large area synchrotron X-ray fluorescence mapping of biological samples', Journal of Instrumentation, vol. 9, no. 12, article no. C12040, pp. 1-6. 4 6
2014	Liu, T, Chien, C-C, Parkinson, L & Thierry, B 2014, 'Advanced micromachining of concave microwells for long term on-chip culture of multicellular tumor spheroids', ACS Applied Materials and Interfaces, vol. 6, no. 11, pp. 8090-8097. 41 35 3
2014	Liu, T, Kempson, IM, de Jonge, MD, Howard, DL & Thierry, B 2014, 'Quantitative synchrotron X-ray fluorescence study of the penetration of transferrin-conjugated gold nanoparticles inside model tumour tissues', Nanoscale, vol. 6 no. 16, pp. 9774-9782. 30 28
2014	Liu, T, Winter, M & Thierry, B 2014, 'Quasi-spherical microwells on superhydrophobic substrates for long term culture of multicellular spheroids and high throughput assays', Biomaterials, vol. 35, no. 23, pp. 6060-6068. 35 38 6
2014	Liu, TM, Yang, C-T, Dieguez, LM, Denman, JA & Thierry, B 2014, 'Robust and flexible fabrication of chemical micropatterns for tumor spheroid preparation', ACS Applied Materials and Interfaces, vol. 6, no. 13, pp. 10162-10171. 7 8
2014	Mejard, R, Griesser, HJ & Thierry, B 2014, 'Optical biosensing for label-free cellular studies', Trends in Analytical Chemistry, vol. 53, pp. 178-186. 46 41
2014	Mejard, RR & Thierry, B 2014, 'Systematic study of the surface plasmon resonance signals generated by cells for sensors with different characteristic lengths', PLoS One, vol. 9, no. 10, pp. 1-11. Open access 14 15
2014	Pai, J-H, Liu, T, Hsu, H-Y, Wedding, AB, Thierry, B & Bagnaninchi, PO 2014, 'Molecular photo-thermal optical coherence phase microscopy using gold nanorods', RSC Advances: An International Journal to Further the Chemical Sciences, vol. 4, no. 51, pp. 27067-27073. 4 3
2014	Sivanathan, K, Gronthos, S, Rojas-Canales, D, Thierry, B & Coates, PT 2014, 'Interferon-gamma modification of mesenchymal stem cells: implications of autologous and alogeneic mesenchymal stem cell therapy in allotransplantation', Stem Cell Reviews, vol. 10, no. 3, pp. 351-375. 116 112 4
2014	Tse, BW-C, Cowin, GJ, Soekmadji, C, Jovanovic, L, Vasireddy, RS, Ling, M-T, Khatria, A, Liu, T, Thierry, B & Russell, P 2014, 'PSMA-targeting iron oxide magnetic nanoparticles enhance MRI of preclinical prostate cancer', Nanomedicine, vol. 10, no. 3, pp. 375-386. Open access 73 68 5
2014	Wan, Y, Winter, M, Delalat, B, Hardingham, JE, Grover, PK, Wrin, J, Voelcker, N, Price, TJ & Thierry, B 2014, 'Nanostructured polystyrene well plates allow unbiased high-throughput characterization of circulating tumor cells', ACS Applied Materials and Interfaces, vol. 6, no. 23, pp. 20828-20836. 29 30
2014	Yang, C-T, Méjard, R, Griesser, HJ, Bagnaninchi, PO & Thierry, B 2014, 'Cellular micromotion monitored by long-range surface plasmon resonance with optical fluctuation analysis', Analytical Chemistry, vol. 87, no. 3, pp 1456-1461. 45 41 1
2013	Liu, T, Cousins, A, Chien, C-C, Kempson, I, Thompson, S, Hwu, Y & Thierry, B 2013, 'Immunospecific targeting of CD45 expressing lymphoid cells: towards improved detection agents of the sentinel lymph node', Cancer Letters, vol. 328, pp. 271-277. Open access 13 12
2013	Mejard, R, Dostálek, J, Huang, C-J, Griesser, H & Thierry, B 2013, 'Tuneable and robust long range surface plasmon resonance for biosensing applications', Optical Materials, vol. 35, no. 12, pp. 2507-2513. 36 29
2012	Beattie, DA, Beaussart, A, Mierczynska-Vasilev, A, Harmer-Bassell, SL, Thierry, B, Puskar, L & Tobin, M 2012, 'Synchrotron FTIR microscopy of Langmuir-Blodgett monolayers and polyelectrolyte multilayers at the solid-solid interface', Langmuir: The ACS Journal of Surfaces and Colloids, vol. 28, no. 3, pp. 1683-1688. 11 8
2012	Fong, W-K, Hanley, TL, Thierry, B, Kirby, N, Waddington, L & Boyd, B 2012, 'Controlling the nanostructure of gold nanorod-lyotropic liquid-crystalline hybrid materials using near-infrared laser irradiation', Langmuir: The ACS Journal of Surfaces and Colloids, vol. 28, no. 40, pp. 14450-14460. 48 43
2012	Liu, TM & Thierry, B 2012, 'A solution to the PEG dilemma: efficient bioconjugation of large gold nanoparticles for biodiagnostic applications using mixed layers', Langmuir: The ACS Journal of Surfaces and Colloids, vol. 28, no. 44, pp. 15634-15642. 42 39
2012	Thierry, B & Griesser, HJ 2012, 'Dense PEG layers for efficient immunotargeting of nanoparticles to cancer cells', Journal of Materials Chemistry, vol. 22, no. 18, pp. 8810-8819. 35 32
2011	Garvey, M, Griesser, S, Griesser, HJ, Thierry, B, Nussio, M, Shapter, J, Ecroyd, H, Giorgetti, S, Bellotti, V, Gerrard, JA & Carver, J 2011, 'Enhanced molecular chaperone activity of the small heat-shock protein aB-crystallin following covalent immobilization onto a solid-phase support', Biopolymers, vol. 95, no. 6, pp. 376-389. 13 11
2011	Kurkuri, MD, Al-Ejeh, F, Shi, JY, Palms, D, Prestidge, C, Griesser, HJ, Brown, MP & Thierry, B 2011, 'Plasma functionalized PDMS microfluidic chips : towards point-of-care capture of circulating tumor cells', Journal of Materials Chemistry, vol. 21, no. 24, pp. 8841-8848. 34 32
2010	Fong, W-K, Hanley, TL, Thierry, B, Kirby, N & Boyd, BJ 2010, 'Plasmonic Nanorods Provide Reversible Control over Nanostructure of Self-Assembled Drug Delivery Materials', Langmuir: The ACS Journal of Surfaces and Colloids, vol. 26, no. 9, pp. 6136-6139. 77 70
2010	Losic, D, Yu, Y, Simovic, S, Thierry, B & Addai-Mensah, J 2010, 'Surface functionalisation of diatoms with dopamine modified iron-oxide nanoparticles: toward magnetically guided drug microcarriers with biologically derived morphologies', Chemical Communications, vol. 46, no. 34, pp. 6323-6325. 172 156
2010	Thierry, B, Kurkuri, M, Shi, JY, Lwin, EMPL & Palms, D 2010, 'Herceptin functionalized microfluidic polydimethylsiloxane devices for the capture of human epidermal growth factor receptor 2 positive circulating breast cancer cells', Biomicrofluidics, vol. 4, article no. 032205, pp. 1-10. Open access 31 29
2010	Truong, MY, Dutta, NK, Choudhury, NR, Kim, M, Elvin, C, Hill, A, Thierry, B & Vasilev, KA 2010, 'A pH-responsive interface derived from resilin-mimetic protein Rec1-Resilin', Biomaterials, vol. 31, no. 15, pp. 4434-4446. 50 46
2010	Vreuls, C, Zocchi, G, Thierry, B, Garitte, G, Griesser, SS, Archambeau, C, Van, dWC, Martial, J & Griesser, H 2010, 'Prevention of bacterial biofilms by covalent immobilization of peptides onto plasma polymer functionalized substrates', Journal of Materials Chemistry, vol. 20, no. 37, pp. 8092-8098. 52 48
2009	Al-Ejeh, F, Darby, JM, Thierry, B & Brown, MP 2009, 'A simplified suite of methods to evaluate chelator conjugation of antibodies : effects on hydrodynamic radius and biodistribution', Nuclear Medicine and Biology, vol. 36, no. 4, pp. 395-402. 32 28
2009	Thierry, B 2009, 'Drug Nanocarriers and Functional Nanoparticles: Applications in Cancer Therapy', Current Drug Delivery, vol. 6, no. 4, pp. 391-403. 73
2009	Thierry, B, Al-Ejeh, F, Brown, MP, Majewski, PJ & Griesser, HJ 2009, 'Immunotargeting of functional nanoparticles for MRI detection of apoptotic tumor cells', Advanced Materials, vol. 21, pp. 541-545. 32 27
2009	Thierry, B, Al-Ejeh, F, Khatri, A, Yuan, Z, Russell, PJ, Ping, S, Brown, MP & Majewski, P 2009, 'Multifunctional core-shell magnetic cisplatin nanocarriers', Chemical Communications, vol. 2009, no. 47, pp. 7348-7350. 27 29
2009	Thierry, B, Ng, J, Krieg, T & Griesser, HJ 2009, 'A robust procedure for the functionalization of gold nanorods and noble metal nanoparticles', Chemical Communications, vol. 13, pp. 1724-1726. 97 94
2008	Majewski, PJ & Thierry, B 2008, 'Superparamagnetic Magnetite Nanoparticles for Bio-applications', Recent Patents on Materials Science, vol. 1, no. 2, pp. 116-127.
2008	Pan, W, W, M, Stretch, J, Thierry, B, Ashton, M & Corlett, R 2008, 'Advanced Imaging Technologies for Mapping Cadaveric Lymphatic Anatomy: Magnetic Resonance and Computed Tomography Lymphangiography', Lymphology, vol. 41, no. 3, pp. 126-130. 4 2
2008	Thierry, B, Jasieniak, M, de Smet, LCPM, Vasilev, KA & Griesser, HJ 2008, 'Reactive epoxy-functionalized thin films by a pulsed plasma polymerization process', Langmuir: The ACS Journal of Surfaces and Colloids, vol. 24, no. 18, pp. 10187-10195. 83 78
2008	Thierry, B, McNiven, S, Finnie, K, Barbe, C & Griesser, HJ 2008, 'Electrostatic Self-Assembly of PEG Copolymers onto Porous Silica Nanoparticles', Langmuir: The ACS Journal of Surfaces and Colloids, vol. 24, no. 15, pp. 8143-8150. 85 82
2008	Thierry, B, Winnik, F, Merhi, Y, Griesser, HJ & Tabrizian, M 2008, 'Biomimetic Hemocompatible Coatings through Immobilization of Hyaluronan Derivatives on Metal Surfaces', Langmuir: The ACS Journal of Surfaces and Colloids, vol. 24, no. 20, pp. 11834-11841. 32 30

Conferences

Year	Output
2015	Cousins, A, Howard, D, Henning, AM, Nelson, MR, Tilley, RD & Thierry, B 2015, 'Application of novel iron core/iron oxide shell nanoparticles to sentinel lymph node identification', SPIE Conference on Micro+Nano Materials, Devices, and Systems, SPIE, vol. 9668, article no. 96685Q, pp. 1-6. Open access
2015	Pocock, KJ, Gao, X, Wang, C, Priest, C, Prestidge, C, Mawatari, K, Kitamori, T & Thierry, B 2015, 'Low-temperature bonded glass-membrane microfluidic device for in vitro organ-on-a-chip cell culture models', SPIE Micro+nano materials, devices, and applications symposium, SPIE - The International Society for Optical Engineering, vol. 9668, article no. 96690W, pp. 1-8. 1
2015	Yang, C-T & Thierry, B 2015, 'Comparison of sensor structures for the signal amplification of surface plasmon resonance immunoassay using enzyme precipitation', SPIE Micro+Nano Materials, Devices, and Applications 2015 Conference, SPIE, vol. 9668, article no. 96682J, pp. 1-7. 2 2
2013	Duy Tran, Wolfrum, B, Stockmann, R, Offenhausser, A & Thierry, B 2013, 'Wafer-scale fabrication of ultra-thin silicon nanowire devices', 2013 13th IEEE International Conference on Nanotechnology (IEEE-NANO 2013), IEEE, pp. 405-409. 3 3

Research

Current research & highlights

Current research areas:

"Intraoperative cancer staging": Ferronova ltd pty has been spun off to develop and commercialize our cancer staging technology. The company is based at the Future Industries Institute and active;y collaborate with the University of Sydney, the Univerity of New South Wales, the Royal Adelaide Hospital and the MD Anderson Cancer Research Institute.
"Molecular Imaging": At the convergence of nanoscience and molecular biology, our research supported by a NHMRC Project Grant in collaboration with Prof Eben Rosenthal at Stanford University aims at developing new molecular imaging tracers able to guide surgery and/or radiotherapy.
Building on the outcomes on an ARC Discovery Grant, we are developing a solid-state Point-of-Care biodiagnostic technology able to quantitatively measure diagnostic biomarkers from finger-prick blood. In collabroration with end-users and stake-holders such as the Royal Flying Doctor Service, we are working towards implemening this technology towards reducing the healthcare disparities between metropolitan and rural Australia. A spin-off company has been launched in 2020 to advance to support this effort: Sanguis Diagnostics.
“Organs-on-chips” technology: With the support of the ARC Centre of Excellence in Convergent Bio Nano Science, our team is actively developing in vitro tissues models, including intestinal tissues and placental tissues. "Tumour-on-chip" models that recapitulate the tumour microenvironment are also being developed towards assisting in the development of more personalised treatments.
"Prenatal diagnostics": We are actively collaborating with clinicians and industry partners to develop the next generation of prenatal diagnostic technology.
"Cancer immunotherapy manufacturing": We are actively collaborating with Carina Biotech to develop improved manufacturing protocols for chimeric antigen receptor (CAR-T) cells, the bioengineered immune cells that are the basis of ground-breaking cellular immunotherapy – a transformative cancer therapy that harnesses the power of a patient’s immune system to fight their cancer.

Research

Patents

Details	Registry	Status
Mapping nanoparticles Thierry, Benjamin; Nelson, Melanie Ruth Maria; Milanova, Valentina; Dmochowska, Nicole; Pham, Thi Hanh Nguyen; Hawkett, Brian Stanley	World	Filed
Sensing of molecules by electrochemical detection of nanoparticles Wolfrum, Bernhard; Adly Hassan, Nouran Yehia; Rinklin, Philipp; Grob, Leroy; Hayden, Oliver; Weiss, Lennart; Tran, Phu Duy; Thierry, Benjamin	World	Granted
Sensor for detection of magnetic particles Cousins, Aidan Mark Francis; Thierry, Benjamin; Wedding, A Bruce; Forero Morales, Daniel	WO	Filed

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Academia Sinica	TAIWAN
Adelaide Pathology Partners	AUSTRALIA
Agency for Science, Technology and Research (A*STAR)	SINGAPORE
Australian National Fabrication Facility Limited	AUSTRALIA
Australian Nuclear Science and Technology Organisation	AUSTRALIA
Australian Synchrotron	AUSTRALIA
Austrian Institute of Technology	SWITZERLAND
Babol Noshirvani University of Technology	IRAN
Bionomics Ltd.	AUSTRALIA
Boutiq Science Ltd	NEW ZEALAND
Carina Biotech	AUSTRALIA
Ceramisphere	AUSTRALIA
CeramiSphere Pty Ltd	AUSTRALIA
Children's Cancer Institute Australia	AUSTRALIA
Chinese Academy of Sciences	CHINA
Chinese University of Hong Kong	HONG KONG
CSIRO Australia (Commonwealth Scientific Industrial Research Organisation)	AUSTRALIA
Curtin University	AUSTRALIA
Dana-Farber Cancer Institute	UNITED STATES
Deakin University	AUSTRALIA
Ferronova	AUSTRALIA
Ferronova Pty Ltd	AUSTRALIA
Ferronova Pty Ltd Salisbury South	AUSTRALIA
First Affiliated Hospital of Zhengzhou University	CHINA
Flinders University	AUSTRALIA
Forschungszentrum Julich	GERMANY
Fudan University	CHINA
Guilin University of Electronic Technology	CHINA
Hanoi University of Science and Technology	VIET NAM
Hanson Institute	AUSTRALIA
Harbin Institute of Technology	CHINA
Harvard University	UNITED STATES
High Performance Computing	SINGAPORE
Imperial College of Science, Technology and Medicine	UNITED KINGDOM
Institute of Medical and Veterinary Science	AUSTRALIA
Laboratoire de Biologie Moleculaire et de Genie genetique	BELGIUM
Leiden University	NETHERLANDS
Leland Stanford Junior University (Stanford)	UNITED STATES
Magnetic Insight	UNITED STATES
Marinova Pty Ltd	AUSTRALIA
McGill University	CANADA
Memorial Sloan Kettering Cancer Centre	UNITED STATES
Minomic Pty Ltd	AUSTRALIA
Monash IVF Group	AUSTRALIA
Monash University	AUSTRALIA
Montreal Heart Institute	CANADA
Murdoch University	AUSTRALIA
Nanjing Agricultural University	CHINA
Nanjing Forestry University	CHINA
Nanjing Medical University	CHINA
Nanjing University	CHINA
Nanyang Technological University	SINGAPORE
National Center for Technological Progress	VIET NAM
Netherlands Cancer Institute	NETHERLANDS
Peter Grunberg Institute (PGI)	GERMANY
Peter MacCallum Cancer Centre	AUSTRALIA
Prince of Wales Hospital	AUSTRALIA
Private Individual	AUSTRALIA
Purdue University	UNITED STATES
Queen Elizabeth Hospital	AUSTRALIA
Queensland University of Technology	AUSTRALIA
Repromed	AUSTRALIA
RMIT University	AUSTRALIA
Royal Adelaide Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
SA Water Corporation	AUSTRALIA
Sechenov First Moscow State Medical University	RUSSIAN FEDERATION
Shanghai Jiao Tong University	CHINA
Shimadzu Biomedical Research Laboratory	CHINA
Soochow Uiniversity	CHINA
Southeast University	CHINA
Southern Medical University	CHINA
St George Hospital	AUSTRALIA
Stanford University	UNITED STATES
Sung Kyun Kwan University	KOREA, REPUBLIC OF (SOUTH)
Swiss Federal Institute of Technology Zurich (ETH)	SWITZERLAND
Tabasco Advance Science and Technology Research Center	MEXICO
Tabriz University of Medical Sciences	IRAN
Tabsco Center for Applied Science and Technology Research	MEXICO
Technical University Munich	GERMANY
The University of Tennessee Health Science Center	UNITED STATES
Universita degli Studi di Pavia (AKA Institute for Advanced Study of Pavia)	ITALY
University College Dublin	IRELAND
University of Adelaide	AUSTRALIA
University of California	UNITED STATES
University of Canterbury	NEW ZEALAND
University of Edinburgh	UNITED KINGDOM
University of Helsinki	FINLAND
University of Melbourne	AUSTRALIA
University of Montreal	CANADA
University of New South Wales	AUSTRALIA
University of Nottingham	UNITED KINGDOM
University Of Oklahoma Norman	UNITED STATES
University of Oulu	FINLAND
University of Pavia	ITALY
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Sydney	AUSTRALIA
University of Technology Sydney	AUSTRALIA
University of Tokyo	JAPAN
University of Toronto	CANADA
University of Warwick	UNITED KINGDOM
University of Wisconsin-Madison	UNITED STATES
UNSW Sydney	AUSTRALIA
WARTN	AUSTRALIA
Western Sydney University	AUSTRALIA
Women's and Children's Hospital	AUSTRALIA
Yangzhou University	CHINA

External engagement & recognition

Engagement/recognition	Year
Editorial Board Member Scientific Reports (Nature Publishing Group)	2018
Panel member, Early Career Fellowship Scheme National Health and Medical Research Council (NHMRC)	2015
Career Development Fellowship National Health and Medical Research Council (NHMRC)	2014
Expert panel member, Program Grant Scheme National Health and Medical Research Council (NHMRC)	2014
Best paper award, Wafer-Scale Fabrication of Ultra-Thin Silicon Nanowire Devices 13th IEEE International Conference on Nanotechnology, Beijing	2013
Panel member, Project Grants Peer Review Process National Health and Medical Research Council (NHMRC)	2012
Career Development Fellowship National Health and Medical Research Council (NHMRC)	2010

Teaching & student supervision

Highlights

Prof Thierry is the head of the BioEngineering group at the UniSA Future Industries Institute. The group is hosted in the state-of-the-art MM building and is a dynamic multidisciplinary team with expertise in physics, nanoscience, pharmaceutical science, molecular biology and biomedical engineering. The group has a strong network of collaborators including with prestigious international research institutions such as the University of Stanford, the University of Tokyo, the Beijing CAS Centre for Nanoscience and Technology, the Forschungszentrum Juelich, Harvard University Dana-Farber Cancer Institute and McGill University. Several current and past members of the group have received prestigious awards, inluding a 2019 Tall Poppy award (Dr. Marnie Winter), a Women in Technology Rising Star Award (Dr Michelle Liu) and a finalist award in the 2018 Prime Minister’s Prizes for Science (Dr Aidan Cousins).

Prof Thierry served as the Program Coordinator of the UniSA NanoBioMaterials Honours degree from 2010 to 2017. He is also teaching in various undergraduate and postgraduate programs, including Monash University and SouthEast University (Nanjing, China).

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
110450 - Development of a theranostic agent for image-guided and radiosensitisation of pancreatic cancer	Current
111188 - Development of brain tumour-targeting ICG nanoformulations for fluorescence-guided neurosurgery	Current
Bioengineering for preterm birth: Developing improved vaginal drug delivery formulations and in vitro models	Current
Developing a Nano-Transistor Biosensor Platform for Point-of-care Diagnostic of Adverse Birth Outcomes	Current
Development of a wearable electrocardiogram nanosensor for screening hypertensive pregnancy complications	Current
Molecular mechanisms of M cell signalling in the small intestine	Current
Next generation bioengineered in vitro tumour models	Current
Non-invasive prenatal testing using extracellular vesicle derived fetal DNA	Current
Solid state biosensors with adjustable dynamic range towards Point of Care diagnostics prognostics of infectious disease	Current
Towards Precision Cancer Radiotherapy through Patient-Derived Tumour on-Chips Reconstructing the Tumour Microenvironment	Current
A nanomedicine approach for immune checkpoint inhibition: towards better and safer cancer immunotherapy	Completed
Amplification of surface plasmon resonance biomolecular binding events: towards improved biosensing based cancer prognostics	Completed
Beyond the gastrointestinal cell layer: replication of the complex oral absorption barrier through enhanced in vitro models for nanoparticulate oral protein delivery	Completed
Bioengineered vascularized microfluidic model: towards improved cancer therapy risk reduction and in vitro evaluation of the metastatic process	Completed
Cation exchange reaction in colloidal nanocrystals: a versatile approach towards improved cancer imaging and radiotherapy	Completed
Detection and characterisation of rare disseminated cancer cells; towards improved patient prognostication	Completed
Development of a solid-state biodiagnostic platform based on indium oxide nanoribbon field effect transistors	Completed
Development of imaging methods/models to study oral vaccination and/or delivery of biologics	Completed
Enrichment and proteomic analysis of placenta-specific extracellular vesicles towards non-invasive diagnosis of preeclampsia	Completed
Formation and characterisation of fucoidan-based polyelectrolyte multilayers for applications in biomaterials	Completed
High density lipoprotein: a natural multi-functional nanomedicine for targeted delivery of radiosensitisers to the tumour microenvironment	Completed
Improving nitric oxide delivery to staphylococcus aureus biofilms	Completed
Isolation and analysis of circulating fetal cells: towards improved non-invasive prenatal diagnosis of genetic disorders	Completed
Long-range surface plasmon resonance biosensing structures for mammalian-cell studies	Completed
Microfluidic intestine-on-a-chip in vitro models for improved mechanistic understanding of intestinal drug and particulate carrier uptake	Completed
Microfluidic intestine-on-a-chip in vitro models for improved understanding of intestinal particulate carrier absorption and interaction with mucus	Completed
Microfluidic manufacturing of chimeric antigen receptor t-cells	Completed
Novel fabrication and operation of integrated silicon nanowire field effect biosensors for reliable detection of cancer prognostic biomarkers	Completed
Novel handheld magnetometer probe for improved intraoperative detection of sentinel lymph nodes in cancer patients	Completed
Radiosensitization of cell sub-populations by gold nanoparticles: cross-correlative microscopy for elucidating fundamental mechanisms	Completed
Single cell analysis of gold and gold-core/silica-shell nanoparticles for radiosensitisation	Completed
Transport of immuno-targeted nanoparticles in 3D tumor spheroids and in vivo models	Completed

Professor Benjamin Thierry

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About me

About me

Future Industries Institute

About me

Professional Associations

Experience

Qualifications

Research

Research focus

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Projects

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Chapters

Journal Articles

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Current research & highlights

Patents

External engagement & recognition

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External engagement & recognition

Editorial Board Member

Panel member, Early Career Fellowship Scheme

Career Development Fellowship

Expert panel member, Program Grant Scheme

Best paper award, Wafer-Scale Fabrication of Ultra-Thin Silicon Nanowire Devices

Panel member, Project Grants Peer Review Process

Career Development Fellowship

Teaching & student supervision

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