Professor John Hayball

Professor UniSA Clinical & Health Sciences

City West Campus (HB6-12)
tel +61 8 830 21202

email john.hayball@unisa.edu.au

Alternative contact

Research Degree Supervisor

About me

John is Research Professor in Immunology and Vaccinology, and heads Expertimental Therapeutics Laboratory within the Clinical and Health Sciences Division at UniSA.

John's group perform basic, translational and clinical research that aims to improve chronic and acute health outcomes, by exploring novel immunotherapeutic approaches to treat and prevent acute and chronic infections, allergy and cancer.

John is focussed on cross-disciplinary collaboration leading to productive translational outcomes in human health, by strategically engaging with research academics, clinicians and industry partners to form integrated research programs with the capacity to address challenging health questions. He has a successful track record ... Read more

UniSA Clinical & Health Sciences

UniSA Clinical & Health Sciences is addressing society’s most critical and emerging health needs through quality teaching, learning and research excellence.

Tweets by @UniversitySA

Research

Research focus

Biological Sciences
Immunology
Biochemistry and Cell Biology
Chemical Sciences
Clinical Sciences

Highlights

Immunology and Inflammation
Vaccinology
Infectious Diseases
Allergy
Cancer Biology

Research

Projects

Excludes commercial-in-confidence projects.

'Intelligent' antibacterial coatings for improving outcomes with infections associated with dialysis catheters, NHMRC - Project Grant, 01/01/2017 - 31/12/2021
Sementis Stage 4 Vaccine Development Research, Sementis Pty Ltd, 15/03/2018 - 01/10/2021
A solid dose vaccine delivery system for SCV, Sementis Pty Ltd, 01/12/2020 - 30/06/2021
Immunisation to protect against transmissible cancers in Tasmanian devils, ARC - Discovery Projects, 01/01/2018 - 30/06/2021
Sementis SCV Vaccine Development Research Support, Sementis Pty Ltd, 01/01/2019 - 01/02/2021
Surface engineered biomaterials to control inflammation, ARC - Discovery Projects, 29/01/2015 - 31/12/2020
Development and production of advanced carbon water purification materials, SIEF STEM+ Business Fellowship Program, 09/12/2017 - 09/12/2020
Development and production of advanced carbon water purification materials, Puratap Pty Ltd, 09/12/2017 - 09/12/2020
SCV vector vaccine manufacturing optimization, Sementis Pty Ltd, 08/11/2017 - 07/11/2020
SCV vector vaccine manufacturing optimization, SIEF STEM+ Business Fellowship Program, 08/11/2017 - 07/11/2020
To develop a method or procedure to reduce environmental impact related to the destruction of PFAS contaminated filters, Membrane Systems Australia, 02/09/2019 - 30/09/2020
To develop a method or procedure to reduce environmental impact related to the destruction of PFAS contaminated filters, Cwth Dept Industry, Science, Energy & Resources, 02/09/2019 - 30/09/2020
CRC-P Industrialisation of a Novel Diagnostic Biosensor for Bladder Cancer, SMR Automotive Australia Pty Ltd, 01/04/2017 - 30/06/2020
Enhanced mulivalent vaccine responses using a novel vaccine vector system, Sementis Pty Ltd, 15/08/2016 - 30/04/2020
Characterising the subtypes of idiopathic inflammatory myopathies (IIMs) in terms of immumopathogenesis, neuroimaging and response to immunotherapy, Central Adelaide Local Health Network Incorporated, 02/01/2017 - 31/12/2019
Development of a prototype immunomodulatory vaccine for cat allergy, Sementis Pty Ltd, 02/09/2016 - 19/12/2019
Development of a prototype immunomodulatory vaccine for cat allergy, SIEF STEM+ Business Fellowship Program, 02/09/2016 - 02/09/2019
Enhanced mulivalent vaccine responses using a novel vaccine vector system (Industry Partner), Sementis Pty Ltd, 23/08/2016 - 31/08/2019
Enhanced multivalent vaccine responses using a novel vaccine vector system, ARC - Linkage Project, 23/08/2016 - 22/08/2019
HMGB1: a novel player in the pathogenesis of inflammatory myositis?, NHMRC - Postgraduate Research Scholarship, 18/02/2016 - 30/06/2019
Innate immunity, MRI and Rituximab projects funding assistance, Myositis Association Australia, 06/03/2017 - 31/03/2018
Process development for SCV vector vaccine production/manufacturing, Sementis Pty Ltd, 21/11/2016 - 29/12/2017
Process development for SCV vector vaccine production/manufacturing, DISER-Innovation Connections Grant, 21/11/2016 - 28/12/2017
Optimisation and testing of prototype (C'Wealth funding), Cwth Dept Industry, Science, Energy & Resources, 15/05/2017 - 08/12/2017
Translating human cancer immunotherapy for use in pets and Tasmanian devils, University of Tasmania, 01/08/2016 - 30/11/2017
Innovation connections puratap development of a chemical detection device, Puratap Pty Ltd, 01/04/2016 - 30/09/2017
Anti-inflammatory/bacterial effects of kinos from Australian and PNG eucalypts, The Royal Society, 02/05/2016 - 02/05/2017
Development of a chemical detection device, DISER-Innovation Connections Grant, 18/04/2016 - 18/04/2017
Modulating Fc receptor signalling to treat and prevent peanut allergy, Channel 7 Children's Research Foundation of SA, 01/01/2015 - 31/12/2016
Development of antibacterial and anti-inflammatory compounds, Wound Management Innovation CRC, 01/09/2013 - 31/12/2016
Investigation of cancer immunotherapy for the Tasmanian devil facial tumour disease, Morris Animal Foundation, 01/08/2014 - 30/11/2016
Animal studies to examine the anti-inflammatory effects of Australian & PNG eucalypt species, Cwth Dept of Foreign Affairs and Trade, 16/11/2015 - 27/11/2016
Analysis of Q fever genome to develop Q-fever vaccine, Sementis Pty Ltd, 01/01/2013 - 30/09/2016
CARPETS: A Phase I Open Label Study of the Safety and Immune effects of an Escalating Dose of Autologous GD2 Chimeric Antigen Receptor-Expressing Peripheral Blood T Cells in Patients with Metastatic B, NHMRC - Project Grant, 01/01/2011 - 30/09/2016
Development of cell line based manufacturing processes for Sementis SCV Vaccines, Sementis Pty Ltd, 26/10/2015 - 26/09/2016
Vaccine development extension and expansion, Sementis Pty Ltd, 04/05/2015 - 03/05/2016
Proof of principle for the use of quantum dots for chlorine detection in tap water, Puratap Pty Ltd, 07/12/2015 - 25/03/2016
The development of a potent new passive immunotherapeutic for the treatment and prevention of bacterial sepsis and septic shock, ARC - Linkage Project, 28/01/2013 - 28/02/2016

Research

Outputs

Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID, ResearcherID or Scopus

Open access indicates that an output is open access.

Chapters

Year	Output
2014	Howley, PM, Diener, KR & Hayball, JD 2014, 'Making an avipoxvirus encoding a tumor-associated antigen and a costimulatory molecule', in MJP Lawman & P D Lawman (eds), Cancer Vaccines: Methods and Protocols, Methods in Molecular Biology, Springer, US, ch. 32, pp. 407-427. 1 1

Journal Articles

Year	Output
2024	Alemie, MN, Bright, R, Nguyen, NH, Truong, VK, Palms, D, Hayball, JD & Vasilev, K 2024, 'Surface chemistry induced IgG unfolding and modulation of immune responses', ACS Applied Materials and Interfaces, vol. 16, no. 38, pp. 50507-50523.
2024	Wang, S, Qiao, X, Cui, Y, Liu, L, Cooper, T, Hu, Y, Lin, J, Liu, H, Wang, M, Hayball, J & Wang, X 2024, 'NCAPH, ubiquitinated by TRIM21, promotes cell proliferation by inhibiting autophagy of cervical cancer through AKT/mTOR dependent signaling', Cell Death and Disease, vol. 15, no. 8, article no. 565, pp. 1-16. Open access 1 1 1
2023	Dabare, PRL, Bachhuka, A, Quek, JY, Marsal, LF, Hayball, J & Vasilev, K 2023, 'Nano-roughness-mediated macrophage polarization for desired host immune response', Small Science, vol. 3, no. 10, article no. 2300080, pp. 1-10. Open access 7 5
2022	Dabare, PRL, Bachhuka, A, Palms, D, Parkinson-Lawrence, E, Hayball, JD, Mierczynska, A & Vasilev, K 2022, 'Surface chemistry mediated albumin adsorption, conformational changes and influence on innate immune responses', Applied Surface Science, vol. 596, article no. 153518, pp. 1-11. 14 13
2022	Eldi, P, Cooper, TH, Prow, NA, Liu, L, Heinemann, GK, Zhang, VJ, Trinidad, AD, Guzman-Genuino, RM, Wulff, P, Hobbs, LM, Diener, KR & Hayball, JD 2022, 'The vaccinia-based Sementis Copenhagen Vector coronavirus disease 2019 vaccine induces broad and durable cellular and humoral immune responses', Immunology and Cell Biology, vol. 100, no. 4, pp. 250-266. Open access 2 2 6
2022	Wang, S, Li, W, Zhang, P, Wang, Z, Ma, X, Liu, C, Vasilev, K, Zhang, L, Zhou, X, Liu, L, Hayball, J, Dong, S, Li, Y, Gao, Y, Cheng, L & Zhao, Y 2022, 'Mechanical overloading induces GPX4-regulated chondrocyte ferroptosis in osteoarthritis via Piezo1 channel facilitated calcium influx', Journal of Advanced Research, vol. 41, pp. 63-75. Open access 80 74
2022	Zhang, Y, Liu, L, Pillman, KA, Hayball, J, Su, YW & Xian, CJ 2022, 'Differentially expressed miRNAs in bone after methotrexate treatment', Journal of Cellular Physiology, vol. 237, no. 1, pp. 965-982. Open access 3 5
2021	Guzman-Genuino, RM, Hayball, JD & Diener, KR 2021, 'Regulatory B cells: dark horse in pregnancy immunotherapy?', Journal of Molecular Biology, vol. 433, no. 1, article no. 166596, pp. 1-14. Open access 15 11 3
2021	Hazlewood, JE, Dumenil, T, Le, TT, Slonchak, A, Kazakoff, SH, Patch, AM, Gray, LA, Howley, PM, Liu, L, Hayball, JD, Yan, K, Rawle, DJ, Prow, NA & Suhrbier, A 2021, 'Injection site vaccinology of a recombinant vaccinia-based vector reveals diverse innate immune signatures', PLoS Pathogens, vol. 17, no. 1, pp. 1-39. Open access 12 11 5
2021	Yu, M, Teo, T, Yang, Y, Li, M, Long, Y, Philip, S, Noll, B, Heinemann, GK, Diab, S, Eldi, P, Mekonnen, L, Anshabo, AT, Rahaman, MH, Milne, R, Hayball, JD & Wang, S 2021, 'Potent and orally bioavailable CDK8 inhibitors: design, synthesis, structure-activity relationship analysis and biological evaluation', European Journal of Medicinal Chemistry, vol. 214, pp. 1-22. Open access 12 11 1
2020	Day, J, Otto, S, Cash, K, Eldi, P, Hissaria, P, Proudman, S, Limaye, V & Hayball, JD 2020, 'Aberrant Expression of High Mobility Group Box Protein 1 in the Idiopathic Inflammatory Myopathies', Frontiers in Cell and Developmental Biology, vol. 8, article no. 226, pp. 1-11. Open access 12 13 1
2020	Garcia-Valtanen, P, Guzman-Genuino, RM, Hayball, JD & Diener, KR 2020, 'Polyinosinic: polycytidylic acid and murine cytomegalovirus modulate expression of murine IL-10 and IL-21 in white adipose tissue', Viruses, vol. 12, no. 5, pp. 1-16. Open access 4 2
2020	Garcia-Valtanen, P, van Dierman, BA, Lakhan, N, Lousberg, EL, Robertson, SA, Hayball, JD & Diener, KR 2020, 'Maternal host responses to poly(I:C) during pregnancy leads to both dysfunctional immune profiles and altered behaviour in the offspring', American Journal of Reproductive Immunology, vol. 84, no. 2. article no. e13260, pp. 1-11. Open access 15 15 1
2020	Nguyen, W, Nakayama, E, Yan, K, Tang, B, Liu, L, Cooper, TH, Hayball, JD, Prow, NA & Suhrbier, A and 12 other authors 2020, 'Arthritogenic alphavirus vaccines: serogrouping versus cross-protection in mouse models', Vaccines, vol. 8, no. 2, article no. 209. Open access 27 26 6
2020	Prow, NA, Liu, L, McCarthy, MK, Walters, K, Kalkeri, R, Geiger, J, Koide, F, Cooper, TH, Eldi, P, Nakayama, E, Diener, KR, Howley, PM, Hayball, JD, Morrison, TE & Suhrbier, A 2020, 'The vaccinia virus based Sementis Copenhagen Vector vaccine against Zika and chikungunya is immunogenic in non-human primates', Vaccines, vol. 5, no. 1, article no. 44, pp. 1-10. Open access 17 13 6
2020	Wang, M, Qiao, X, Cooper, T, Pan, W, Liu, L, Hayball, J, Lin, J, Cui, X, Zhou, Y, Zhang, S, Zou, Y, Zhang, R & Wang, X 2020, 'HPV E7-mediated NCAPH ectopic expression regulates the carcinogenesis of cervical carcinoma via PI3K/AKT/SGK pathway', Cell Death and Disease, vol. 11, no. 12, article no. 1049, pp. 1-16. Open access 21 24 1
2020	Zhao, Y, Qiu, C, Wang, W, Peng, J, Vasilev, K, Liu, L, Hayball, J & Li, W 2020, 'Cortistatin protects against intervertebral disc degeneration through targeting mitochondrial ROS-dependent NLRP3 inflammasome activation', Theranostics, vol. 10, no. 15, pp. 7015-7033. Open access 101 93
2019	Afinjuomo, OF, Barclay, TG, Parikh, A, Chung, R, Song, Y, Nagalingam, G, Triccas, J, Wang, L, Liu, L, Hayball, JD, Petrovsky, N & Garg, S 2019, 'Synthesis and characterization of pH-sensitive inulin conjugate of isoniazid for monocyte-targeted delivery', Pharmaceutics, vol. 11, no. 11, article no. 555, pp. 1-19. Open access 19 18 2
2019	Afinjuomo, OF, Barclay, TG, Parikh, A, Song, Y, Chung, R, Wang, L, Liu, L, Hayball, JD, Petrovsky, N & Garg, S 2019, 'Design and characterization of inulin conjugate for improved intracellular and targeted delivery of pyrazinoic acid to monocytes', Pharmaceutics, vol. 11, no. 5, pp. 1-22. Open access 9 9 2
2019	Eldi, P, Cooper, T, Ward, M & Hayball, JD 2019, 'How emerging vaccine technologies are pushing disease prevention boundaries', International Pharmacy Journal, vol. 37, no. 1, pp. 16-19.
2019	Gonzalez Garcia, LE, MacGregor, MN, Visalakshan, RM, Ninan, N, Cavallaro, AA, Trinidad, AD, Zhao, Y, Hayball, AJD & Vasilev, K 2019, 'Self-sterilizing antibacterial silver-loaded microneedles', Chemical Communications, vol. 55, no. 2, pp. 171-174. 67 69 56
2019	Grubor-Bauk, B, Wijesundara, D, Masavuli, M, Abbink, P, Peterson, R, Prow, N, Larocca, R, Mekonnen, Z, Shrestha, A, Eyre, N, Beard, M, Gummow, J, Carr, J, Robertson, S, Hayball, J, Barouch, D & Gowans, E 2019, 'NS1 DNA vaccination protects against Zika infection through T cell-mediated immunity in immunocompetent mice', Science Advances, vol. 5, no. 12, article no. eaax2388, pp. 1-15. Open access 53 46 132
2019	Guzman-Genuino, RM, Dimova, T, You, Y, Aldo, P, Hayball, JD, Mor, G & Diener, KR 2019, 'Trophoblasts promote induction of a regulatory phenotype in B cells that can protect against detrimental T cell-mediated inflammation', American Journal of Reproductive Immunology, vol. 82, no. 6, article no. e13187, pp. 1-16. Open access 13 11 1
2019	Guzman-Genuino, RM, Eldi, P, Garcia-Valtanen, P, Hayball, JD & Diener, KR 2019, 'Uterine B cells exhibit regulatory properties during the peri-implantation stage of murine pregnancy', Frontiers in Immunology, vol. 10, article no. 2899, pp. 1-12. Open access 19 16 4
2019	Li, W, Wang, W, Liu, L, Qu, R, Chen, X, Qiu, C, Li, J, Hayball, J, Liu, L, Chen, J, Wang, X, Pan, X & Zhao, Y 2019, 'GDF11 antagonizes TNF-α-induced inflammation and protects against the development of inflammatory arthritis in mice', The FASEB Journal, vol. 33, no. 3, pp. 3317-3329. Open access 29 29 3
2019	Lundquist, N, Sweetman, MJ, Scroggie, KR, Worthington, MJ, Esdaile, LJ, Alboaiji, SF, Plush, SE, Hayball, JD & Chalker, JM 2019, 'Polymer supported carbon for safe and effective remediation of PFOA- and PFOS-contaminated water', ACS Sustainable Chemistry and Engineering, vol. 7, no. 13, pp. 11044-11049. Open access 47 43 68
2019	Pincher, DW, Bader, CA, Hayball, JD, Plush, SE & Sweetman, MJ 2019, 'Graphene quantum dot embedded hydrogel for dissolved iron sensing', Chemistry Select, vol. 4, no. 33, pp. 9640-9646. 16 15 3
2019	Qu, R, Chen, X, Yuan, Y, Wang, W, Qiu, C, Liu, L, Li, P, Zhang, Z, Vasilev, K, Liu, L, Hayball, J, Zhao, Y, Li, Y & Li, W 2019, 'Ghrelin fights against titanium particle-induced inflammatory osteolysis through activation of β-catenin signaling pathway', Inflammation, vol. 42, no. 5, pp. 1652-1665. 11 11 1
2019	Sweetman, MJ, Hickey, SM, Brooks, DA, Hayball, JD & Plush, SE 2019, 'A practical guide to prepare and synthetically modify graphene quantum dots', Advanced Functional Materials, vol. 29, no. 14, article no. 1808740, pp. 1-18. Open access 85 83 1
2019	Visalakshan, RM, Cavallaro, AA, MacGregor, MN, Lawrence, EP, Koynov, K, Hayball, JD & Vasilev, K 2019, 'Nanotopography-induced unfolding of fibrinogen modulates leukocyte binding and activation', Advanced Functional Materials, vol. 29, no. 14, article no.1807453, pp. 1-12. Open access 37 37 1
2019	Visalakshan, RM, MacGregor, MN, Sasidharan, S, Ghazaryan, A, Mierczynska-Vasilev, AM, Morsbach, S, Mailander, V, Landfester, K, Hayball, JD & Vasilev, K 2019, 'Biomaterial surface hydrophobicity-mediated serum protein adsorption and immune responses', ACS Applied Materials and Interfaces, vol. 11, no. 31, pp. 27615-27623. 135 132 3
2019	Wang, L, Song, Y, Parikh, A, Joyce, P, Chung, R, Liu, L, Afinjuomo, OF, Hayball, JD, Petrovsky, N, Barclay, TG & Garg, S 2019, 'Doxorubicin-loaded delta inulin conjugates for controlled and targeted drug delivery: development, characterization, and in vitro evaluation', Pharmaceutics, vol. 11, no. 11, pp. 1-17. Open access 24 23 3
2019	Zhao, Y, Li, Y, Qu, R, Chen, X, Wang, W, Qiu, C, Liu, B, Pan, X, Liu, L, Vasilev, K, Hayball, J, Dong, S & Li, W 2019, 'Cortistatin binds to TNF-α receptors and protects against osteoarthritis', EBioMedicine, vol. 41, pp. 556-570. Open access 58 49
2018	Gillam, TA, Sweetman, MJ, Bader, CA, Morrison, JL, Hayball, JD, Brooks, DA & Plush, SE 2018, 'Bright lights down under: Metal ion complexes turning the spotlight on metabolic processes at the cellular level', Coordination Chemistry Reviews, vol. 375, pp. 234-255. 9 7 2
2018	Lynch, JP, Werder, RB, Loh, Z, Sikder, MAA, Hayball, J, Diener, K & Phipps, S and 19 other authors 2018, 'Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion', Journal of Experimental Medicine, vol. 215, pp. 537-557. Open access 59 55 28
2018	Pavathuparambil Abdul Manaph, N, Al-Hawwas, M, Liu, L, Liu, D, Hayball, J & Zhou, XF 2018, 'Facial vein injection of human cells in severe combined immunodeficiency (SCID) neonatal mice', MethodsX, vol. 5, pp. 1281-1286. Open access 1
2018	Prow, NA, Jimenez Martinez, R, Hayball, JD, Howley, PM & Suhrbier, A 2018, 'Poxvirus-based vector systems and the potential for multi-valent and multi-pathogen vaccines', Expert Review of Vaccines, vol. 17, no. 10, pp. 925-934. 32 29 11
2018	Prow, NA, Liu, L, Nakayama, E, Cooper, TH, Yan, K, Eldi, P, Hazlewood, JE, Tang, B, Le, TT, Setoh, YX, Khromykh, AA, Hobson-Peters, J, Diener, KR, Howley, PM, Hayball, JD & Suhrbier, A 2018, 'A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses', Nature Communications, vol. 9, article no. 1230, pp. 1-12. Open access 63 61 82
2018	Sweetman, MJ, Sebben, D, Noll, BD, Wang, WH, May, S, Mebberson, N, Plush, SE & Hayball, JD 2018, 'A rapid technique to determine performance and efficiency of activated carbon water filters', Water Science and Technology: Water Supply, vol. 18, no. 2, pp. 371-382. Open access 8 7
2018	Visalakshan, RM, MacGregor, MN, Cavallaro, AA, Sasidharan, S, Bachhuka, A, Mierczynska-Vasilev, AM, Hayball, JD & Vasilev, K 2018, 'Creating nano-engineered biomaterials with well-defined surface descriptors', ACS Applied Nano Materials, vol.1, no. 8, pp. 2796-2807. 33 31 2
2018	Zhang, W, Song, Y, Eldi, P, Guo, X, Hayball, JD, Garg, S & Albrecht, H 2018, 'Targeting prostate cancer cells with hybrid elastin-like polypeptide/liposome nanoparticles', International Journal of Nanomedicine, vol. 13, pp. 293-305. Open access 40 30 5
2017	Bachhuka, A, Hayball, JD, Smith, LE & Vasilev, KA 2017, 'The interplay between surface nanotopography and chemistry modulates collagen I and III deposition by human dermal fibroblasts', ACS Applied Materials and Interfaces, vol. 9, pp. 5874-5884. 25 25
2017	Day, J, Limaye, V, Proudman, S, Hayball, JD & Hissaria, P 2017, 'The utility of monitoring peripheral blood lymphocyte subsets by flow cytometric analysis in patients with rheumatological diseases treated with rituximab', Autoimmunity Reviews, vol. 16, no. 5, pp. 542-547. 4 4 2
2017	Day, J, Otto, S, Proudman, S, Hayball, JD & Limaye, V 2017, 'Dysregulated innate immune function in the aetiopathogenesis of idiopathic inflammatory myopathies', Autoimmunity Reviews, vol. 16, no. 1, pp. 87-95. 16 15 3
2017	Eldi, P, Cooper, TH, Liu, L, Prow, NA, Diener, KR, Howley, PM, Suhrbier, A & Hayball, JD 2017, 'Production of a Chikungunya vaccine using a CHO Cell and attenuated viral-based platform technology', Molecular Therapy, vol. 25, no. 10. pp. 2332-2344. Open access 17 17 10
2017	Flies, AS, Blackburn, NB, Lyons, AB, Hayball, JD & Woods, GM 2017, 'Comparative analysis of immune checkpoint molecules and their potential role in the transmissible Tasmanian devil facial tumor disease', Frontiers in Immunology, vol. 8, pp. 1-27. Open access 14 15 71
2017	Garcia-Valtanen, P, Guzman-Genuino, RM, Williams, DL, Hayball, JD & Diener, KR 2017, 'Evaluation of trained immunity by β-1, 3 (d)-glucan on murine monocytes in vitro and duration of response in vivo', Immunology and Cell Biology, vol. 95, pp. 601-610. Open access 69 66 6
2017	Jaeger, D, Ndi, CP, Crocoll, C, Simpson, BS, Khakimov, B, Guzman-Genuino, RM, Hayball, JD, Xing, X, Bulone, V, Weinstein, P, Moller, BL & Semple, SJ 2017, 'Isolation and structural characterization of echinocystic acid triterpenoid saponins from the Australian medicinal and food plant Acacia ligulata', Journal of Natural Products, vol. 80, pp. 2692-2698. 17 16 9
2017	Liu, L, Cooper, T, Eldi, P, Garcia-Valtanen, P, Diener, KR, Howley, PM & Hayball, JD 2017, 'Transient dominant host-range selection using Chinese hamster ovary cells to generate marker-free recombinant viral vectors from vaccinia virus', Biotechniques: The Journal of Laboratory Technology for Bioresearch, vol. 62, no. 4, pp. 183-187. Open access 4 4 1
2017	Moldenhauer, LM, DIener, KR, Hayball, JD & Robertson, SA 2017, 'An immunogenic phenotype in paternal antigen-specific CD8 + T cells at embryo implantation elicits later fetal loss in mice', Immunology and Cell Biology, vol. 95, no. 8, pp. 705-715. 25 25 14
2017	Stevens, NE, Chapman, MJ, Fraser, CK, Kuchel, TR, Hayball, JD & Diener, KR 2017, 'Therapeutic targeting of HMGB1 during experimental sepsis modulates the inflammatory cytokine profile to one associated with improved clinical outcomes', Scientific Reports, vol. 7, article no. 5850, pp. 1-14. Open access 81 83 7
2017	Sweetman, MJ, May, S, Mebberson, N, Pendleton, P, Vasilev, K, Plush, SE & Hayball, J 2017, 'Activated carbon, carbon nanotubes and graphene: materials and composites for advanced water purification', Journal of Carbon Research, vol. 3, no. 2, pp. 1-29. Open access 89 3
2017	Wijesundara, DK, Yu, W, Quah, BJ, Eldi, P, Hayball, JD, Diener, KR, Voskoboinik, I, Gowans, EJ & Grubor-Bauk, B 2017, 'Cytolytic DNA vaccine encoding lytic perforin augments the maturation of - and antigen presentation by - dendritic cells in a time-dependent manner', Scientific Reports, vol. 7, no. 1, article no. 8530, pp. 1-8. Open access 7 8 1
2016	Christo, S, Bachhuka, A, Diener, KR, Mierczynska, A, Hayball, JD & Vasilev, K 2016, 'The role of surface nanotopography and chemistry on primary neutrophil and macrophage cellular responses', Advanced Healthcare Materials, vol. 5, no. 8, pp. 956-965. 91 89
2016	Christo, S, Bachhuka, A, Diener, KR, Vasilev, K & Hayball, JD 2016, 'The contribution of inflammasome components on macrophage response to surface nanotopography and chemistry', Scientific Reports, vol. 6, article no. 26207, pp. 1-9. Open access 35 36
2016	Christo, S, Diener, KR, Manavis, J, Grimbaldeston, MA, Bachhuka, A, Vasilev, K & Hayball, J 2016, 'Inflammasome components ASC and AIM2 modulate the acute phase of biomaterial implant-induced foreign body responses', Scientific Reports, vol. 6, article no. 20635, pp. 1-14. Open access 21 19
2016	Diener, KR, Robertson, SA, Hayball, JD & Lousberg, EL 2016, 'Multi-parameter flow cytometric analysis of uterine immune cell fluctuations over the murine estrous cycle', Journal of Reproductive Immunology, vol. 113, pp. 61-67. 15 15 2
2016	Flies, AS, Lyons, AB, Corcoran, LM, Papenfuss, AT, Murphy, JM, Knowles, GW, Woods, GM & Hayball, JD 2016, 'PD-L1 is not constitutively expressed on Tasmanian devil facial tumor cells but is strongly upregulated in response to IFN-gamma and can be expressed in the tumor microenvironment', Frontiers in Immunology, vol. 7, article no. 581, pp. 1-13. Open access 33 33 67
2016	Gargett, T, Yu, W, Dotti, G, Yvon, ES, Christo, SN, Hayball, JD, Lewis, ID, Brenner, MK & Brown, MP 2016, 'GD2-specific CAR T cells undergo potent activation and deletion following antigen encounter but can be protected from activation-induced cell death by PD-1 blockade', Molecular Therapy, vol. 24, no. 6, pp. 1135-1149. Open access 289 263 11
2016	Lakhan, N, Stevens, NE, Diener, KR & Hayball, JD 2016, 'CoVaccine HT adjuvant is superior to Freund's adjuvants in eliciting antibodies against the endogenous alarmin HMGB1', Journal of Immunological Methods, vol. 439, pp. 37-43. Open access 2 12
2016	Stevens, NE, Hatjopolous, A, Fraser, CK, Alsharifi, M, Diener, KR & Hayball, JD 2016, 'Preserved antiviral adaptive immunity following polyclonal antibody immunotherapy for severe murine influenza infection', Scientific Reports, vol. 6, article no. 29154, pp. 1-13. Open access 8 9
2016	Tao, B, Bernardo, K, Eldi, P, Chegeni, N, Wiese, M, Colella, A, Kral, A, Hayball, J, Smith, W, Forsyth, K & Chataway, T 2016, 'Extended boiling of peanut progressively reduces IgE allergenicity while retaining T cell reactivity', Clinical and Experimental Allergy, vol. 46, no. 11, pp. 1004-1014. 40 36 45
2016	Zhang, W, Garg, S, Eldi, P, Zhou, FH-h, Johnson, IR, Brooks, DA, Lam, F, Rychkov, G, Hayball, JD & Albrecht, H 2016, 'Targeting prostate cancer cells with genetically engineered polypeptide-based micelles displaying gastrin-releasing peptide', International Journal of Pharmaceutics, vol. 513, pp.270-279. 27 25 4
2015	Bachhuka, A, Christo, S, Cavallaro, A, Diener, K, Mierczynska, A, Smith, L, Marian, R, Manavis, J, Hayball, J & Vasilev, KA 2015, 'Hybrid core/shell microparticles and their use for understanding biological processes', Journal of Colloid and Interface Science, vol. 457, pp. 9-17. Open access 18 18 3
2015	Bachhuka, A, Hayball, JD, Smith, LE & Vasilev, KA 2015, 'Effect of surface chemical functionalities on collagen deposition by primary human dermal fibroblasts', ACS Applied Materials and Interfaces, vol. 74, no. 42, pp. 23767-23775. 31 30
2015	Christo, SN, Diener, KR & Hayball, JD 2015, 'The functional contribution of calcium ion flux heterogeneity in T cells', Immunology and Cell Biology, vol. 93, no. 8, pp. 694-704. 6 18 10
2015	Christo, SN, Diener, KR, Bachhuka, A, Vasilev, K & Hayball, JD 2015, 'Innate immunity and biomaterials at the nexus: friends or foes', BioMed Research International, vol. 2015, article ID 342304, pp. 1-23. Open access 110 103
2015	Christo, SN, Diener, KR, Nordon, RE, Brown, MP, Griesser, HJ, Vasilev, K, Christo, FC & Hayball, JD 2015, 'Scrutinizing calcium flux oscillations in T lymphocytes to deduce the strength of stimulus', Scientific Reports, vol. 5, article no. 7760, pp. 1-8. Open access 25 25 2
2015	Corrigan, F, Wu, Y, Tuke, J, Coller, JK, Rice, KC, Diener, KR, Hayball, JD, Watkins, LR, Somogyi, AA & Hutchinson, MR 2015, 'Alcohol-induced sedation and synergistic interactions between alcohol and morphine: a key mechanistic role for Toll-like receptors and MyD88-dependent signaling', Brain Behavior and Immunity, vol. 45, pp. 245-252. Open access 21 21 2
2015	Mon, HH, Christo, SN, Ndi, CP, Jasieniak, M, Rickard, H, Hayball, JD, Griesser, HJ & Semple, SJ 2015, 'Serrulatane diterpenoid from Eremophila neglecta exhibits bacterial biofilm dispersion and inhibits release of pro-inflammatory cytokines from activated macrophages', Journal of Natural Products, vol. 78, no. 12, pp. 3031-3040. Open access 22 22 19
2015	Nenke, M, Rankin, W, Chapman, M, Stevens, N, Diener, K, Hayball, J, Lewis, J & Torpy, D 2015, 'Depletion of high-affinity corticosteroid-binding globulin corresponds to illness severity in sepsis and septic shock; clinical implications', Clinical Endocrinology, vol. 82, pp. 801-807. 26 43 1
2015	Nguyen, TM, Arthur, A, Panagopoulos, R, Paton, S, Hayball, JD, Zannettino, AC, Purton, LE, Matsuo, K & Gronthos, S 2015, 'EphB4 expressing stromal cells exhibit an enhanced capacity for hematopoietic stem cell maintenance', Stem Cells, vol. 33, no. 9, pp. 2838-2849. Open access 29 28 1
2015	Ramiasa, M, Cavallaro, A, Mierczynska, A, Christo, S, Gleadle, J, Hayball, J & Vasilev, K 2015, 'Plasma polymerised polyoxazoline thin films for biomedical applications', Chemical Communications, vol. 51, pp. 4279-4282. 84 81 7
2015	Taheri, S, Cavallaro, A, Christo, SN, Majewski, P, Barton, M, Hayball, J & Vasilev, K 2015, 'Antibacterial plasma polymer films conjugated with phospholipid encapsulated silver nanoparticles', ACS Biomaterial Science and Engineering, vol. 1, no. 12, pp. 1278-1286. 42 38 3
2014	Liu, L, Cooper, T, Howley, PM & Hayball, JD 2014, 'From crescent to mature virion: vaccinia virus assembly and maturation', Viruses, vol. 6, no. 10, pp. 3787-3808. Open access 40 34 4
2014	Locock, KE, Michl, TD, Stevens, N, Hayball, JD, Vasilev, K, Postma, A, Griesser, HJ, Meagher, L & Haeussler, M 2014, 'Antimicrobial polymethacrylates synthesized as mimics of tryptophan-rich cationic peptides', ACS Macro Letters, vol. 3 no. 4, pp. 319-323. 94 90
2014	Michl, TD, Locock, KE, Stevens, NE, Hayball, JD, Vasilev, K, Postma, A, Qu, Y, Traven, A, Haeussler, M, Meagher, L & Griesser, HJ 2014, 'RAFT-derived antimicrobial polymethacrylates: elucidating the impact of end-groups on activity and cytotoxicity', Polymer Chemistry, vol. 5, no. 19, pp. 5813-5822. 71 67 3
2014	Simovic, S, Diener, K, Bachhuka, A, Kant, K, Losic, D, Hayball, J, Brownc, M & Vasilev, K 2014, 'Controlled release and bioactivity of the monoclonal antibody rituximab from a porous matrix: a potential in situ therapeutic device', Materials Letters, vol. 130, pp. 210-214. 10 10
2014	Taheri, S, Cavallaro, AA, Christo, S, Smith, L, Majewski, P, Barton, M, Hayball, J & Vasilev, K 2014, 'Substrate independent silver nanoparticle based antibacterial coatings', Biomaterials, vol. 35, no. 16, pp. 4601-4609. 139 122 3
2013	Cathcart, S, Della Vedova, C, Immink, M, Proeve, M & Hayball, J 2013, 'Mindfulness training does not reduce inflammatory cytokine levels in chronic tension-type headache', Journal of Pain Management, vol. 6, no. 3, pp. 235-238. 3
2013	Della Vedova, C, Cathcart, S, Dohnalek, AJ, Lee, V, Hutchinson, MR, Immink, MA & Hayball, J 2013, 'Peripheral interleukin-1β levels are elevated in chronic tension-type headache patients', Pain Research and Management, vol. 18, no. 6, pp. 301-306. Open access 34 26
2013	Diener, KR, Al-Dasooqi, N, Lousberg, EL & Hayball, JD 2013, 'The multifunctional alarmin HMGB1 with roles in the pathophysiology of sepsis and cancer', Immunology and Cell Biology, vol. 91, no. 7, pp. 443-450. 43 71
2013	Kaiko, GE, Loh, Z, Spann, K, Lynch, JP, Lalwani, A, Zheng, Z, Davidson, S, Uematsu, S, Akira, S, Hayball, J, Diener, KR, Baines, KJ, Simpson, JL, Foster, PS & Phipps, S 2013, 'Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice', Journal of Allergy and Clinical Immunology, vol. 131, no. 5, pp. 1331-1339. 61 58
2013	Locock, KE, Michl, TD, Valentin, JD, Vasilev, K, Hayball, JD, Qu, Y, Traven, A, Griesser, HJ, Meagher, L & Haeussler, M 2013, 'Guanylated polymethacrylates: a class of potent antimicrobial polymers with low hemolytic activity', Biomacromolecules, vol. 14, no. 11, pp. 4021-4031. 187 179
2013	Nguyen, TM, Arthur, A, Hayball, JD & Gronthos, S 2013, 'EphB and ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells', Stem Cells and Development, vol. 22, no. 20, pp. 2751-2764. Open access 62 61
2013	Stevens, NE, Fraser, C, Alsharifi, M, Brown, MP, Diener, KR & Hayball, JD 2013, 'An empirical approach towards the efficient and optimal production of influenza-neutralizing ovine polyclonal antibodies demonstrates that the novel adjuvant CoVaccine HT™ is functionally superior to Freund's adjuvant', PLoS One, vol. 8, no. 7, article no. e68895, pp. 1-10. Open access 10 8
2012	Cathcart, S, Bhullar, N, Immink, MA, Della Vedova, C & Hayball, JD 2012, 'Pain sensitivity mediates the relationship between stress and headache intensity in chronic tension-type headache', Pain Research and Management, vol. 17, no. 6, pp. 377-380. Open access 20 21
2012	Christo, SN, Sarvestani, GT, Griesser, SS, Coad, BR, Griesser, HJ, Vasilev, K, Brown, MP, Diener, KR & Hayball, JD 2012, 'Individual and population quantitative analyses of calcium flux in T-Cells activated on functionalized material surfaces', Australian Journal of Chemistry: An International Journal for Chemical Science, vol. 65, no. 1, pp. 45-49. 7 7
2012	Coad, BR, Scholz, T, Vasilev, K, Hayball, JD, Short, RD & Griesser, HJ 2012, 'Functionality of proteins bound to plasma polymer surfaces', ACS Applied Materials and Interfaces, vol. 4, no. 5, pp. 2455-2463. 53 53
2012	Coad, BR, Vasilev, K, Diener, KR, Hayball, JD, Short, RD & Griesser, HJ 2012, 'Immobilized streptavidin gradients as bioconjugation platforms', Langmuir: The ACS Journal of Surfaces and Colloids, vol. 28, no. 5, pp. 2710-2717. 34 34
2012	Diener, KR, Christo, SN, Griesser, SS, Sarvestani, GT, Vasilev, K, Griesser, HJ & Hayball, JD 2012, 'Solid-state capture and real-time analysis of individual T cell activation via self-assembly of binding multimeric proteins on functionalized materials surfaces', Acta Biomaterialia, vol. 8, no. 1, pp. 99-107. 14 14
2012	Miller, DS, Brown, MP, Howley, PM & Hayball, JD 2012, 'Current and emerging immunotherapeutic approaches to treat and prevent peanut allergy', Expert Review of Vaccines, vol. 11, no. 12, pp. 1471-1481. 7 6
2012	Wu, Y, Lousberg, EL, Moldenhauer, LM, Hayball, JD, Coller, J, Rice, KC, Watkins, LR, Somogyi, A & Hutchinson, MR 2012, 'Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice', British Journal of Pharmacology, vol. 165, no. 5, pp. 1319-1329. Open access 68 57
2011	Furuya, Y, Chan, J, Wan, E-C, Koskinen, A, Diener, KR, Hayball, JD, Regner, M, Müllbacher, A & Alsharifi, M 2011, 'Gamma-irradiated influenza virus uniquely induces IFN-I mediated lymphocyte activation independent of the TLR7/MyD88 pathway', PLoS One, vol. 6, no. 10, article no. e25765, pp. 1-12. Open access 17 16
2011	Guerin, LR, Moldenhauer, LM, Prins, JR, Bromfield, JJ, Hayball, JD & Robertson, SA 2011, 'Seminal fluid regulates accumulation of FOXP3+ regulatory T cells in the preimplantation mouse uterus through expanding the FOXP3+ cell pool and CCL19-mediated recruitment', Biology of Reproduction, vol. 85, no. 2, pp. 397-408. Open access 177 166
2011	Lousberg, EL, Diener, KR, Brown, MP & Hayball, JD 2011, 'Innate immune recognition of poxviral vaccine vectors', Expert Review of Vaccines, vol. 10, no. 10, pp. 1435-1449. 15 16
2011	Lousberg, EL, Diener, KR, Fraser, CK, Phipps, S, Foster, PS, Chen, W, Uematsu, S, Akira, S, Robertson, SA, Brown, MP & Hayball, JD 2011, 'Antigen-specific T-cell responses to a recombinant fowlpox virus are dependent on MyD88 and interleukin-18 and independent of toll-like receptor 7 (TLR7)- and TLR9-mediated innate immune recognition', Journal of Virology, vol. 85, no. 7, pp. 3385-3396. Open access 12 11
2011	Wu, Y, Lousberg, EL, Moldenhauer, LM, Hayball, JD, Robertson, SA, Coller, JK, Watkins, LR, Somogyi, AA & Hutchinson, MR 2011, 'Attenuation of microglial and IL-1 signaling protects mice from acute alcohol-induced sedation and/or motor impairment', Brain Behavior and Immunity, vol. 25, no. s1, pp. 155-164. 69 54
2010	Diener, KR, Need, E, Buchanan, G & Hayball, JD 2010, 'TGF-β signalling and immunity in prostate tumourigenesis', Expert Opinion on Therapeutic Targets, vol. 14, no. 2, pp. 179-192. 19 20
2010	Fraser, C, Diener, KR, Lousberg, E, Both, Gw, Ward, L, Brown, MP & Hayball, JD 2010, 'Induction of both cellular and humoral immunity following a rational prime-boost immunization regimen that incorporates recombinant ovine atadenovirus and fowlpox virus', Clinical and Vaccine Immunology, vol. 17, no. 11, pp. 1679-1686. Open access 5 5
2010	Fraser, CK, Brown, MP, Diener, KR & Hayball, JD 2010, 'Unravelling the complexity of cancer-immune system interplay', Expert Review of Anticancer Therapy: An Essential Contribution to Decision Making in Cancer Care, vol. 10, no. 6, pp. 917-934. 5 5
2010	Fraser, CK, Lousberg, EL, Guerin, LR, Hughes, TP, Brown, MP, Diener, KR & Hayball, JD 2010, 'Dasatinib alters the metastatic phenotype of B16-OVA melanoma in vivo', Cancer Biology and Therapy, vol. 10, no. 7, pp. 715-727. Open access 11 11
2010	Lousberg, EL, Fraser, CK, Tovey, MG, Diener, KR & Hayball, JD 2010, 'Type I interferons mediate the innate cytokine response to recombinant fowlpox virus but not the induction of plasmacytoid dendritic cell-dependent adaptive immunity', Journal of Virology, vol. 84, no. 13, pp. 6549-6563. Open access 19 18
2010	Moldenhauer, LM, Hayball, JD & Robertson, SA 2010, 'Utilising T cell receptor transgenic mice to define mechanisms of maternal T cell tolerance in pregnancy', Journal of Reproductive Immunology, vol. 87, no. 1-2, pp. 1-13. 39 37
2010	Moldenhauer, LM, Keenihan, SN, Hayball, JD & Robertson, SA 2010, 'GM-CSF is an essential regulator of T cell activation competence in uterine dendritic cells during early pregnancy in mice', Journal of Immunology, vol. 185, no. 11, pp. 7085-7096. Open access 80 77
2009	Diener, K, Woods, AE, Manavis, J, Brown, MP & Hayball, JD 2009, 'Transforming growth factor-β-mediated signaling in T lymphocytes impacts on prostate-specific immunity and early prostate tumor progression', Laboratory Investigation, vol. 89, no. 2, pp. 142-151. Open access 14 14
2009	Fraser, C, Blake, SJ, Diener, KR, Lyons, A, Brown, MP, Hughes, T & Hayball, JD 2009, 'Dasatinib inhibits recombinant viral antigen-specific murine CD4+ and CD8+ T-cell responses and NK-cell cytolytic activity in vitro and in vivo', Experimental Hematology, vol. 37, no. 2, pp. 256-265. 58 56
2009	Fraser, C, Lousberg, EL, Kumar, R, Hughes, TP, Diener, KR & Hayball, JD 2009, 'Dasatinib inhibits the secretion of TNF-α following TLR stimulation in vitro and in vivo', Experimental Hematology, vol. 37, no. 12, pp. 1435-1444. 38 30
2009	Moldenhauer, LM, Diener, K, Thring, DM, Brown, MP, Hayball, JD & Robertson, SA 2009, 'Cross-presentation of male seminal fluid antigens elicits T cell activation to initiate the female immune response to pregnancy', Journal of Immunology, vol. 182, no. 12, pp. 8080-8093. Open access 119 189
2009	Robertson, SA, Guerin, LR, Moldenhauer, LM & Hayball, JD 2009, 'Activating T regulatory cells for tolerance in early pregnancy - the contribution of seminal fluid', Journal of Reproductive Immunology, vol. 83 no. 1-2, pp. 109-116. 151 138
2008	Diener, K, Lousberg, EL, Beukema, EL, Yu, A, Howley, PM, Brown, MP & Hayball, JD 2008, 'Recombinant fowlpox virus elicits transient cytotoxic T cell responses due to suboptimal innate recognition and recruitment of T cell help', Vaccine, vol. 26, no. 29-30, pp. 3566-3573. 10 7
2008	Diener, K, Moldenhauer, LM, Lyons, AB, Brown, MP & Hayball, JD 2008, 'Human Flt-3 ligand-mobilized dendritic cells require additional activation to drive effective immune responses', Experimental Hematology, vol. 36, no. 1, pp. 51-60. 18 18
2008	Fraser, C, Hayball, JD, Lyons, A, Hughes, T & Blake, S 2008, 'Dasatinib suppresses in vitro natural killer cell cytotoxicity', Blood, vol. 111, no. 8, pp. 4415-4416. Open access 67 67
2008	Wong, M-X, Hayball, JD & Jackson, D 2008, 'PECAM-1-regulated signaling thresholds control tolerance in anergic transgenic B-cells', Molecular Immunology, vol. 45, no. 6, pp. 1767-1781. 3 3

Conferences

Year	Output
2016	Visalakshan, RM, Cavallaro, A, Smith, LE, MacGregor-Ramiasa, M, Hayball, J & Vasilev, K 2016, 'Downstream influences of oxazoline plasma polymerisation conditions on chemical and biological interactions', Chemeca conference 2016, Engineers Australia, article no. 3405675, pp. 840-848.

Research

Patents

Details	Registry	Status
Analysing intracellular calcium flux in cells including T cells Hayball, John Dominic; Diener, Kerrilyn Roxanne; Christo, Susan; Nordon, Robert; Christo, Farid Christo	WO	Filed
Attenuated poxvirus vector based vaccine for protection against covid-19 Prow, Natalie; Howley, Paul; Cooper, Tamara; Hayball, John; Diener, Kerrilyn R; Liu, Liang; Eldi, Preethi	US	Filed
Sorbent compositions Chalker, Justin; Hayball, John; Plush, Sally; Sweetman, Martin Jay	AU	Filed

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Austin Research Institute	AUSTRALIA
Australian Genome Research Facility	AUSTRALIA
Australian National University	AUSTRALIA
Baylor College of Medicine	UNITED STATES
Canterbury Health Laboratories	NEW ZEALAND
Chalmers University of Technology	SWEDEN
CSIRO Australia (Commonwealth Scientific Industrial Research organisation)	AUSTRALIA
East Tennessee State University	UNITED STATES
Flinders Medical Centre	AUSTRALIA
Flinders University	AUSTRALIA
Hanson Institute	AUSTRALIA
Harvard University	UNITED STATES
Houston Methodist Hospital	UNITED STATES
Institute of Medical and Veterinary Science	AUSTRALIA
John Curtin School of Medical Research	AUSTRALIA
John Hunter Hospital	AUSTRALIA
Jubail Industrial College	SAUDI ARABIA
Keio University	JAPAN
Ludwig Institute for Cancer Research	AUSTRALIA
Max Planck Institute for Polymer	GERMANY
Max Planck Institute for Polymer Research	GERMANY
Monash University	AUSTRALIA
National Institute of Alcohol Abuse and Alcoholism	UNITED STATES
National Institute on Drug Abuse	UNITED STATES
New York University	UNITED STATES
Osaka Prefecture University	JAPAN
Osaka University	JAPAN
Peking University	CHINA
Peter MacCallum Cancer Centre	AUSTRALIA
Puratap Pty Ltd	AUSTRALIA
Qilu Hospital of Shandong University	CHINA
QIMR Berghofer Medical Research Institute	AUSTRALIA
Queensland Institute of Medical Research	AUSTRALIA
Queensland University of Technology	AUSTRALIA
Rovira i Virgili University	SPAIN
Royal Adelaide Hospital	AUSTRALIA
SA Pathology	AUSTRALIA
Sementis	AUSTRALIA
Shandong First Medical University	CHINA
Shandong University	CHINA
South Australian Health and Medical and Research Institute (SAHMRI)	AUSTRALIA
Southern Research Institute	UNITED STATES
Tasmanian Department of Primary Industries	AUSTRALIA
The Australian Wine Research Institute	AUSTRALIA
University of Adelaide	AUSTRALIA
University of British Columbia	CANADA
University of California, Riverside	UNITED STATES
University of Canberra	AUSTRALIA
University of Colorado Denver	UNITED STATES
University of Copenhagen	DENMARK
University of Groningen	NETHERLANDS
University of Melbourne	AUSTRALIA
University of New South Wales	AUSTRALIA
University of Newcastle	AUSTRALIA
University of North Carolina at Chapel Hill	UNITED STATES
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Sydney	AUSTRALIA
University of Tasmania	AUSTRALIA
University of Technology Sydney	AUSTRALIA
University of Texas	UNITED STATES
University of Wollongong	AUSTRALIA
Vaxine Pty Ltd	AUSTRALIA
Virax Holdings Limited	AUSTRALIA
Walter and Eliza Hall Institute of Medical Research	AUSTRALIA
Women's and Children's Hospital	AUSTRALIA
Yale University	UNITED STATES

External engagement & recognition

Engagement/recognition	Year
Editorial Board Member Scientific Reports (Nature Publishing Group)	2018
Affiliated Associate Professor School of Medicine, University of Adelaide	2017
Affiliated Associate Professor School of Paediatrics and Reproductive Health, University of Adelaide	2017
Affiliated Member Robinson Research Institute, University of Adelaide	2017
Associate Member Hanson Institute (SA Pathology and Royal Adelaide Hospital)	2017
Founding Member South Australian Institutional Biosafety Committee Network Forum	2017
Member Australasian Society of Immunology (ASI)	2017
Member British Society for Immunology	2017
Member, Gene Technology Technical Advisory Committee Office of the Gene Technology Regulator (OGTR), Department of Health and Ageing, Australian Government	2017
Member, Gene Technology Technical Advisory Committee Office of the Gene Technology Regulator (OGTR), Department of Health and Ageing, Australian Government	2016
Member, Gene Technology Technical Advisory Committee Office of the Gene Technology Regulator (OGTR), Department of Health and Ageing, Australian Government	2015
Member, Gene Technology Technical Advisory Committee Office of the Gene Technology Regulator (OGTR), Department of Health and Ageing, Australian Government	2014
Member, Gene Technology Technical Advisory Committee Office of the Gene Technology Regulator (OGTR), Department of Health and Ageing, Australian Government	2013

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
Assessment of almond -specific antibody levels in participants from the Almond Weight Loss Study	Current
Inflammatory responses to biomaterials	Current
Preclinical evaluation of passive and active immunotherapies for melanoma	Current
A novel role for 14-3-3zeta in coordinating interneuron development through regulation of Rac1 and non-canonical Shh signalling	Completed
AFM nanomechanical analysis of nanostructured anti-bacterial surfaces	Completed
Antimicrobial coatings for biomedical and wound healing devices	Completed
Biological actions of antibacterial compounds covalently attached onto solid material surfaces or released diffusively from materials	Completed
Characterisation of immune-mediated necrotising myopathy	Completed
Development and evaluation of ovine polyclonal antibody therapies for the treatment of severe influenza infection and bacterial sepsis	Completed
Dissecting the mechanisms involved in the induction of immunity to recombinant fowlpox virus	Completed
Elucidating the role of regulatory B cells in early pregnancy	Completed
Evaluation of antigen-specific immune responses elicited by single and multiple pathogen vaccines designed using a vaccinia virus-based vector system	Completed
Evaluation of the immunomodulatory properties of dasatinib for improved application in combinatorial immunotherapy regimens	Completed
Intelligent materials that respond to the presence of bacteria	Completed
Investigation of the toxicokinetics of per- and polyfluoroalkyl substances (PFAS) in cattle and application to risk assessment	Completed
Modulation of biological responses by nano- engineered surfaces	Completed
Nano engineered surfaces to control biological response	Completed
Optimising CAR T cell manufacturing for solid cancers	Completed
Peroxisome proliferator-activated receptor gamma interacts with sphingosine 1-phosphate to regulate vascular function	Completed
Surface engineered microneedles for delivery of bioactive compounds	Completed
The effect of nanotopography on cell-surface interaction	Completed
The impact of genetic predictors of opioid dependence on neuroimmune and endocrine markers in healthy adults	Completed
The innate recognition of murine cytomegalovirus during the pre-implantation period and consequences for pregnancy	Completed
The interleukin-3 receptor alpha chain drives cellular proliferation and mediates microenvironment interaction in normal and malignant haematopoiesis	Completed
The role of Eph/ephrin interactions in mesenchymal stem cell-mediated support of haematopoiesis and immune cell regulation	Completed
The role of haptenation in penicillin and cephalosporin allergy	Completed
The role of platelets in vasculogenic mimicry	Completed
The use of biomaterials to investigate and modulate innate and adaptive immunity	Completed
Understanding a novel replication-deficient poxviral-based vector platform	Completed

Professor John Hayball

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About me

About me

UniSA Clinical & Health Sciences

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Highlights

Projects

Outputs

Chapters

Journal Articles

Conferences

Current research & highlights

Patents

External engagement & recognition

Collaborations

Collaborations

External engagement & recognition

Editorial Board Member

Affiliated Associate Professor

Affiliated Associate Professor

Affiliated Member

Associate Member

Founding Member

Member

Member

Member, Gene Technology Technical Advisory Committee

Member, Gene Technology Technical Advisory Committee

Member, Gene Technology Technical Advisory Committee

Member, Gene Technology Technical Advisory Committee

Member, Gene Technology Technical Advisory Committee

Teaching & student supervision

Courses and programs

Research degree supervision

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