A/Prof Kerrilyn Diener Experimental Therapeutics Laboratory Deputy Head kerrilyn.diener@unisa.edu.au 0422 911549
Dr Tamara Cooper Experimental Therapeutics Laboratory Manager tamara.cooper@unisa.edu.au 8302 1139
John is Research Professor in Immunology and Vaccinology, and heads Expertimental Therapeutics Laboratory within the Clinical and Health Sciences Division at UniSA.
John's group perform basic, translational and clinical research that aims to improve chronic and acute health outcomes, by exploring novel immunotherapeutic approaches to treat and prevent acute and chronic infections, allergy and cancer.
John is focussed on cross-disciplinary collaboration leading to productive translational outcomes in human health, by strategically engaging with research academics, clinicians and industry partners to form integrated research programs with the capacity to address challenging health questions. He has a successful track record ... Read more
About me
John is Research Professor in Immunology and Vaccinology, and heads Expertimental Therapeutics Laboratory within the Clinical and Health Sciences Division at UniSA.
John's group perform basic, translational and clinical research that aims to improve chronic and acute health outcomes, by exploring novel immunotherapeutic approaches to treat and prevent acute and chronic infections, allergy and cancer.
John is focussed on cross-disciplinary collaboration leading to productive translational outcomes in human health, by strategically engaging with research academics, clinicians and industry partners to form integrated research programs with the capacity to address challenging health questions. He has a successful track record of research grant funding from the NHMRC, MRFF and ARC, as well as other National and International competative funding schemes.
He has a long history of biotechnology and pharmaceutical industry engagement, including executive, advisory and consultancies roles, and a track record of successful commercial collaborative and contractual research funding, and award of competative industry-leveraged federal and state government funding schemes.
About me
About me
Doctor of Philosophy University of London
Bachelor of Science The University of Adelaide
Diploma in Molecular Biology Imperial College
Research
Excludes commercial-in-confidence projects.
'Intelligent' antibacterial coatings for improving outcomes with infections associated with dialysis catheters, NHMRC - Project Grant, 01/01/2017 - 31/12/2021
Sementis Stage 4 Vaccine Development Research, Sementis Pty Ltd, 15/03/2018 - 01/10/2021
Immunisation to protect against transmissible cancers in Tasmanian devils, ARC - Discovery Projects, 01/01/2018 - 30/06/2021
A solid dose vaccine delivery system for SCV, Sementis Pty Ltd, 01/12/2020 - 30/06/2021
Sementis SCV Vaccine Development Research Support, Sementis Pty Ltd, 01/01/2019 - 01/02/2021
Surface engineered biomaterials to control inflammation, ARC - Discovery Projects, 29/01/2015 - 31/12/2020
Development and production of advanced carbon water purification materials, Puratap Pty Ltd, 09/12/2017 - 09/12/2020
Development and production of advanced carbon water purification materials, SIEF STEM+ Business Fellowship Program, 09/12/2017 - 09/12/2020
SCV vector vaccine manufacturing optimization, SIEF STEM+ Business Fellowship Program, 08/11/2017 - 07/11/2020
SCV vector vaccine manufacturing optimization, Sementis Pty Ltd, 08/11/2017 - 07/11/2020
To develop a method or procedure to reduce environmental impact related to the destruction of PFAS contaminated filters, Membrane Systems Australia, 02/09/2019 - 30/09/2020
To develop a method or procedure to reduce environmental impact related to the destruction of PFAS contaminated filters, Cwth Dept Industry, Science, Energy & Resources, 02/09/2019 - 30/09/2020
CRC-P Industrialisation of a Novel Diagnostic Biosensor for Bladder Cancer, SMR Automotive Australia Pty Ltd, 01/04/2017 - 30/06/2020
Enhanced mulivalent vaccine responses using a novel vaccine vector system, Sementis Pty Ltd, 15/08/2016 - 30/04/2020
Characterising the subtypes of idiopathic inflammatory myopathies (IIMs) in terms of immumopathogenesis, neuroimaging and response to immunotherapy, Central Adelaide Local Health Network Incorporated, 02/01/2017 - 31/12/2019
Development of a prototype immunomodulatory vaccine for cat allergy, Sementis Pty Ltd, 02/09/2016 - 19/12/2019
Development of a prototype immunomodulatory vaccine for cat allergy, SIEF STEM+ Business Fellowship Program, 02/09/2016 - 02/09/2019
Enhanced mulivalent vaccine responses using a novel vaccine vector system (Industry Partner), Sementis Pty Ltd, 23/08/2016 - 31/08/2019
Enhanced multivalent vaccine responses using a novel vaccine vector system, ARC - Linkage Project, 23/08/2016 - 22/08/2019
HMGB1: a novel player in the pathogenesis of inflammatory myositis?, NHMRC - Postgraduate Research Scholarship, 18/02/2016 - 30/06/2019
Innate immunity, MRI and Rituximab projects funding assistance, Myositis Association Australia, 06/03/2017 - 31/03/2018
Process development for SCV vector vaccine production/manufacturing, Sementis Pty Ltd, 21/11/2016 - 29/12/2017
Process development for SCV vector vaccine production/manufacturing, DISER-Innovation Connections Grant, 21/11/2016 - 28/12/2017
Optimisation and testing of prototype (C'Wealth funding), Cwth Dept Industry, Science, Energy & Resources, 15/05/2017 - 08/12/2017
Translating human cancer immunotherapy for use in pets and Tasmanian devils, University of Tasmania, 01/08/2016 - 30/11/2017
Innovation connections puratap development of a chemical detection device, Puratap Pty Ltd, 01/04/2016 - 30/09/2017
Anti-inflammatory/bacterial effects of kinos from Australian and PNG eucalypts, The Royal Society, 02/05/2016 - 02/05/2017
Development of a chemical detection device, DISER-Innovation Connections Grant, 18/04/2016 - 18/04/2017
Development of antibacterial and anti-inflammatory compounds, Wound Management Innovation CRC, 01/09/2013 - 31/12/2016
Modulating Fc receptor signalling to treat and prevent peanut allergy, Channel 7 Children's Research Foundation of SA, 01/01/2015 - 31/12/2016
Investigation of cancer immunotherapy for the Tasmanian devil facial tumour disease, Morris Animal Foundation, 01/08/2014 - 30/11/2016
Animal studies to examine the anti-inflammatory effects of Australian & PNG eucalypt species, Cwth Dept of Foreign Affairs and Trade, 16/11/2015 - 27/11/2016
Analysis of Q fever genome to develop Q-fever vaccine, Sementis Pty Ltd, 01/01/2013 - 30/09/2016
CARPETS: A Phase I Open Label Study of the Safety and Immune effects of an Escalating Dose of Autologous GD2 Chimeric Antigen Receptor-Expressing Peripheral Blood T Cells in Patients with Metastatic B, NHMRC - Project Grant, 01/01/2011 - 30/09/2016
Development of cell line based manufacturing processes for Sementis SCV Vaccines, Sementis Pty Ltd, 26/10/2015 - 26/09/2016
Vaccine development extension and expansion, Sementis Pty Ltd, 04/05/2015 - 03/05/2016
Proof of principle for the use of quantum dots for chlorine detection in tap water, Puratap Pty Ltd, 07/12/2015 - 25/03/2016
The development of a potent new passive immunotherapeutic for the treatment and prevention of bacterial sepsis and septic shock, ARC - Linkage Project, 28/01/2013 - 28/02/2016
Research
Research outputs for the last seven years are shown below. Some long-standing staff members may have older outputs included. To see earlier years visit ORCID, ResearcherID or Scopus
Open access indicates that an output is open access.
Year | Output |
---|---|
2024 |
|
2024 |
Open access
|
2023 |
Open access
7
|
2022 |
14
12
|
2022 |
Open access
2
2
3
|
2022 |
Open access
77
67
|
2022 |
Open access
3
5
|
2021 |
Open access
14
10
3
|
2021 |
Open access
11
11
5
|
2021 |
Open access
12
11
1
|
2020 |
Open access
12
13
1
|
2020 |
Open access
4
2
|
2020 |
Open access
15
15
1
|
2020 |
Open access
27
26
6
|
2020 |
Open access
16
13
6
|
2020 |
Open access
19
22
1
|
2020 |
Open access
98
91
|
2019 |
Open access
19
18
2
|
2019 |
Open access
9
9
2
|
2019 |
|
2019 |
66
66
56
|
2019 |
Open access
51
44
131
|
2019 |
Open access
13
11
1
|
2019 |
Open access
18
15
4
|
2019 |
Open access
28
28
3
|
2019 |
Open access
46
43
68
|
2019 |
15
14
3
|
2019 |
11
11
1
|
2019 |
Open access
84
83
1
|
2019 |
Open access
36
37
1
|
2019 |
132
127
3
|
2019 |
Open access
24
23
3
|
2019 |
Open access
55
48
|
2018 |
9
7
2
|
2018 |
Open access
59
55
28
|
2018 |
Open access
1
|
2018 |
32
29
11
|
2018 |
Open access
62
60
87
|
2018 |
Open access
8
7
|
2018 |
33
31
2
|
2018 |
Open access
40
28
5
|
2017 |
25
24
|
2017 |
4
4
2
|
2017 |
16
15
3
|
2017 |
Open access
17
17
10
|
2017 |
Open access
14
15
71
|
2017 |
Open access
71
66
6
|
2017 |
17
16
9
|
2017 |
Open access
4
4
1
|
2017 |
25
25
8
|
2017 |
Open access
80
83
7
|
2017 |
Open access
89
3
|
2017 |
Open access
7
8
1
|
2016 |
90
86
|
2016 |
Open access
35
36
|
2016 |
Open access
20
18
|
2016 |
15
15
2
|
2016 |
Open access
33
34
67
|
2016 |
Open access
287
262
11
|
2016 |
Open access
2
12
|
2016 |
Open access
8
8
1
|
2016 |
38
35
45
|
2016 |
27
25
4
|
2015 |
Open access
18
18
3
|
2015 |
31
30
|
2015 |
6
18
10
|
2015 |
Open access
109
102
1
|
2015 |
Open access
25
25
3
|
2015 |
Open access
21
21
2
|
2015 |
Open access
22
22
19
|
2015 |
26
43
1
|
2015 |
Open access
27
27
1
|
2015 |
83
80
7
|
2015 |
40
37
3
|
2014 |
Open access
40
34
4
|
2014 |
94
89
|
2014 |
70
67
3
|
2014 |
10
10
|
2014 |
136
120
4
|
2013 |
3
|
2013 |
Open access
34
26
|
2013 |
43
71
|
2013 |
61
58
|
2013 |
186
178
|
2013 |
Open access
62
61
|
2013 |
Open access
10
8
|
2012 |
Open access
20
21
|
2012 |
7
7
|
2012 |
52
52
|
2012 |
34
34
|
2012 |
14
14
|
2012 |
6
6
|
2012 |
Open access
67
57
|
2011 |
Open access
17
16
|
2011 |
Open access
176
164
|
2011 |
15
16
|
2011 |
Open access
12
11
|
2011 |
69
54
|
2010 |
19
20
|
2010 |
Open access
5
5
|
2010 |
5
5
|
2010 |
Open access
11
11
|
2010 |
Open access
19
18
|
2010 |
39
37
|
2010 |
Open access
80
77
|
2009 |
Open access
14
14
|
2009 |
58
56
|
2009 |
37
30
|
2009 |
Open access
119
189
|
2009 |
151
138
|
2008 |
10
7
|
2008 |
18
18
|
2008 |
Open access
67
67
|
2008 |
3
3
|
Research
Research
Details | Registry | Status |
---|---|---|
Analysing intracellular calcium flux in cells including T cells Hayball, John Dominic; Diener, Kerrilyn Roxanne; Christo, Susan; Nordon, Robert; Christo, Farid Christo |
WO | Filed |
Attenuated poxvirus vector based vaccine for protection against covid-19 Prow, Natalie; Howley, Paul; Cooper, Tamara; Hayball, John; Diener, Kerrilyn R; Liu, Liang; Eldi, Preethi |
US | Filed |
Chalker, Justin; Hayball, John; Plush, Sally; Sweetman, Martin Jay |
AU | Filed |
External engagement & recognition
Organisation | Country |
---|---|
Austin Research Institute | AUSTRALIA |
Australian Genome Research Facility | AUSTRALIA |
Australian National University | AUSTRALIA |
Baylor College of Medicine | UNITED STATES |
Canterbury Health Laboratories | NEW ZEALAND |
Chalmers University of Technology | SWEDEN |
CSIRO Australia (Commonwealth Scientific Industrial Research organisation) | AUSTRALIA |
East Tennessee State University | UNITED STATES |
Flinders Medical Centre | AUSTRALIA |
Flinders University | AUSTRALIA |
Hanson Institute | AUSTRALIA |
Harvard University | UNITED STATES |
Houston Methodist Hospital | UNITED STATES |
Institute of Medical and Veterinary Science | AUSTRALIA |
John Curtin School of Medical Research | AUSTRALIA |
John Hunter Hospital | AUSTRALIA |
Jubail Industrial College | SAUDI ARABIA |
Keio University | JAPAN |
Ludwig Institute for Cancer Research | AUSTRALIA |
Max Planck Institute for Polymer | GERMANY |
Max Planck Institute for Polymer Research | GERMANY |
Monash University | AUSTRALIA |
National Institute of Alcohol Abuse and Alcoholism | UNITED STATES |
National Institute on Drug Abuse | UNITED STATES |
New York University | UNITED STATES |
Osaka Prefecture University | JAPAN |
Osaka University | JAPAN |
Peking University | CHINA |
Peter MacCallum Cancer Centre | AUSTRALIA |
Puratap Pty Ltd | AUSTRALIA |
Qilu Hospital of Shandong University | CHINA |
QIMR Berghofer Medical Research Institute | AUSTRALIA |
Queensland Institute of Medical Research | AUSTRALIA |
Queensland University of Technology | AUSTRALIA |
Rovira i Virgili University | SPAIN |
Royal Adelaide Hospital | AUSTRALIA |
SA Pathology | AUSTRALIA |
Sementis | AUSTRALIA |
Shandong First Medical University | CHINA |
Shandong University | CHINA |
South Australian Health and Medical and Research Institute (SAHMRI) | AUSTRALIA |
Southern Research Institute | UNITED STATES |
Tasmanian Department of Primary Industries | AUSTRALIA |
The Australian Wine Research Institute | AUSTRALIA |
University of Adelaide | AUSTRALIA |
University of British Columbia | CANADA |
University of California, Riverside | UNITED STATES |
University of Canberra | AUSTRALIA |
University of Colorado Denver | UNITED STATES |
University of Copenhagen | DENMARK |
University of Groningen | NETHERLANDS |
University of Melbourne | AUSTRALIA |
University of New South Wales | AUSTRALIA |
University of Newcastle | AUSTRALIA |
University of North Carolina at Chapel Hill | UNITED STATES |
University of Queensland | AUSTRALIA |
University of South Australia | AUSTRALIA |
University of Sydney | AUSTRALIA |
University of Tasmania | AUSTRALIA |
University of Technology Sydney | AUSTRALIA |
University of Texas | UNITED STATES |
University of Wollongong | AUSTRALIA |
Vaxine Pty Ltd | AUSTRALIA |
Virax Holdings Limited | AUSTRALIA |
Walter and Eliza Hall Institute of Medical Research | AUSTRALIA |
Women's and Children's Hospital | AUSTRALIA |
Yale University | UNITED STATES |
External engagement & recognition
Engagement/recognition | Year |
---|---|
Editorial Board MemberScientific Reports (Nature Publishing Group) |
2018 |
Affiliated Associate ProfessorSchool of Medicine, University of Adelaide |
2017 |
Affiliated Associate ProfessorSchool of Paediatrics and Reproductive Health, University of Adelaide |
2017 |
Affiliated MemberRobinson Research Institute, University of Adelaide |
2017 |
Associate MemberHanson Institute (SA Pathology and Royal Adelaide Hospital) |
2017 |
Founding MemberSouth Australian Institutional Biosafety Committee Network Forum |
2017 |
MemberAustralasian Society of Immunology (ASI) |
2017 |
MemberBritish Society for Immunology |
2017 |
Member, Gene Technology Technical Advisory CommitteeOffice of the Gene Technology Regulator (OGTR), Department of Health and Ageing, Australian Government |
2017 |
Member, Gene Technology Technical Advisory CommitteeOffice of the Gene Technology Regulator (OGTR), Department of Health and Ageing, Australian Government |
2016 |
Member, Gene Technology Technical Advisory CommitteeOffice of the Gene Technology Regulator (OGTR), Department of Health and Ageing, Australian Government |
2015 |
Member, Gene Technology Technical Advisory CommitteeOffice of the Gene Technology Regulator (OGTR), Department of Health and Ageing, Australian Government |
2014 |
Member, Gene Technology Technical Advisory CommitteeOffice of the Gene Technology Regulator (OGTR), Department of Health and Ageing, Australian Government |
2013 |
Teaching & student supervision
Supervisions from 2010 shown
Thesis title | Student status |
---|---|
Assessment of almond -specific antibody levels in participants from the Almond Weight Loss Study | Current |
Inflammatory responses to biomaterials | Current |
Preclinical evaluation of passive and active immunotherapies for melanoma | Current |
A novel role for 14-3-3zeta in coordinating interneuron development through regulation of Rac1 and non-canonical Shh signalling | Completed |
AFM nanomechanical analysis of nanostructured anti-bacterial surfaces | Completed |
Antimicrobial coatings for biomedical and wound healing devices | Completed |
Biological actions of antibacterial compounds covalently attached onto solid material surfaces or released diffusively from materials | Completed |
Characterisation of immune-mediated necrotising myopathy | Completed |
Development and evaluation of ovine polyclonal antibody therapies for the treatment of severe influenza infection and bacterial sepsis | Completed |
Dissecting the mechanisms involved in the induction of immunity to recombinant fowlpox virus | Completed |
Elucidating the role of regulatory B cells in early pregnancy | Completed |
Evaluation of antigen-specific immune responses elicited by single and multiple pathogen vaccines designed using a vaccinia virus-based vector system | Completed |
Evaluation of the immunomodulatory properties of dasatinib for improved application in combinatorial immunotherapy regimens | Completed |
Intelligent materials that respond to the presence of bacteria | Completed |
Investigation of the toxicokinetics of per- and polyfluoroalkyl substances (PFAS) in cattle and application to risk assessment | Completed |
Modulation of biological responses by nano- engineered surfaces | Completed |
Nano engineered surfaces to control biological response | Completed |
Optimising CAR T cell manufacturing for solid cancers | Completed |
Peroxisome proliferator-activated receptor gamma interacts with sphingosine 1-phosphate to regulate vascular function | Completed |
Surface engineered microneedles for delivery of bioactive compounds | Completed |
The effect of nanotopography on cell-surface interaction | Completed |
The impact of genetic predictors of opioid dependence on neuroimmune and endocrine markers in healthy adults | Completed |
The innate recognition of murine cytomegalovirus during the pre-implantation period and consequences for pregnancy | Completed |
The interleukin-3 receptor alpha chain drives cellular proliferation and mediates microenvironment interaction in normal and malignant haematopoiesis | Completed |
The role of Eph/ephrin interactions in mesenchymal stem cell-mediated support of haematopoiesis and immune cell regulation | Completed |
The role of haptenation in penicillin and cephalosporin allergy | Completed |
The role of platelets in vasculogenic mimicry | Completed |
The use of biomaterials to investigate and modulate innate and adaptive immunity | Completed |
Understanding a novel replication-deficient poxviral-based vector platform | Completed |