Associate Professor Nicole Pratt

AsResProf in Biostatistics & Pharmacoepidemiology School of Pharmacy and Medical Sciences

City East Campus (P6-31)
tel +61 8 830 22818

email Nicole.Pratt@unisa.edu.au

Research Degree Supervisor

About me

Dr Nicole Pratt is an Associate Professor and Deputy Director of the Quality Use of Medicines and Pharmacy Research Centre, Sansom Institute, University of South Australia. She is a member of the Drug Utilisation Subcommittee (DUSC) of the Australian Department of Health Pharmaceutical Benefits Advisory Committee (PBAC).

She has a particular interest in new statistical methodologies to study the effectiveness and safety of medicine use and in the development of tools for post-marketing surveillance of medicines.

Nicole is a chief investigator of an NHMRC Cenre of Research Excellence in post-market surveillance of medicines and medical devices and leads the evaluation of the Department of Veterans Affairs, Veterans’ Medicines Advice ... Read more

School of Pharmacy and Medical Sciences

With standout facilities and strong industry links, the School prepares students for careers in health and medical science.

Tweets by @UniversitySA

Research

Research themes

An age friendly world
Healthy futures

Research focus

Public Health and Health Services
Clinical Sciences
Medical and Health Sciences
Pharmacology and Pharmaceutical Sciences
Biomedical Engineering

Highlights

Pharmacoepidemiology
Statistical Research Methods
Quality Use of Medicines

Research

Projects

Excludes commercial-in-confidence projects.

Large scale evidence generation for the utilisation and safety of biologic medicines, NHMRC - Project Grant, 01/01/2019 - 31/12/2022
Veterans' Medicines Advice and Therapeutics Education Services (Veterans' MATES) Program, Commonwealth Department of Veterans' Affairs, 01/09/2015 - 30/06/2021
CVC Mental Health Pilot, Commonwealth Department of Veterans' Affairs, 03/01/2018 - 31/12/2020
Enhancing joint replacement outcomes through national data linkage, NHMRC - Project Grant, 01/01/2018 - 31/12/2020
ReMinDAR Trial: Reducing medicine induced deterioration and adverse reactions trial, Department of Health, 15/09/2017 - 30/06/2020
Veterans' Medicines Advice and Therapeutics Education Services (Veterans' MATES) Program, Commonwealth Department of Veterans' Affairs, 01/09/2015 - 18/12/2018
Centre of Research Excellence in post-market surveillance of medicines and medical devices, NHMRC - Centre of Research Excellence, 01/11/2012 - 31/10/2018
Data analytics, evaluation of new and emerging analysis methods, advisory services re data analytics, strategic planning, processess and capability improvements., Department of Health, 04/12/2017 - 30/06/2018
Understanding medicine safety, NHMRC - Early Career Fellowship, 26/03/2012 - 25/03/2016
First step of WHO/EMP work for improving medicines use in countries, World Health Organisation Malaysia, 16/11/2015 - 12/02/2016
Medical and advisory services, Therapeutic Goods Administration, 01/01/2014 - 30/12/2015
Use of DVA data to inform NPS program evaluation, National Prescribing Service, 01/02/2010 - 29/01/2012

Research

Outputs

Research since 2008 is shown below. To see earlier years visit ORCID, ResearcherID or Scopus

Open access indicates that an output is open access.

Highlights

Year	Output
2018	Hallas, J, Wang, S V, Gagne, JJ, Schneeweiss, S, Pratt, N & Pottegaard, A 2018, 'Hypothesis-free screening of large administrative databases for unsuspected drug-outcome associations', European Journal of Epidemiology, vol. 33, no. 6, pp. 545-555. Open access 3 3 2
2018	Pratt, N, Kerr, M, Barratt, J, Kemp-Casey, A, Kalisch Ellett, L, Ramsay, E & Roughead, E 2018, 'The validity of the Rx-Risk Comorbidity Index using medicines mapped to the Anatomical Therapeutic Chemical (ATC) Classification System', BMJ Open, vol. 8, no. 4, pp. 1-8. Open access 14 14 4
2018	Raman, SR, Man, KK, Bahmanyar, S, Berard, A, Pratt, NL, Roughead, EE & Wong, IC and 26 other authors 2018, 'Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases', The Lancet Psychiatry, vol. 5, no. 10, pp. 824-835. Open access 17 16 132
2017	Lai, EC-C, Pratt, N, Hsieh, C-Y, Lin, S-J, Pottegård, A, Roughead, EE, Kao Yang, Y-H & Hallas, J 2017, 'Sequence symmetry analysis in pharmacovigilance and pharmacoepidemiologic studies', European Journal of Epidemiology, vol. 32, no. 7, pp. 567-582. 15 11 4
2016	Hripcsak, G, Ryan, PB, Duke, JD, Shah, NH, Park, RW, Huser, V, Suchard, MA, Schuemie, MJ, DeFalco, FJ, Perotte, A, Banda, JM, Reich, CG, Schilling, LM, Matheny, ME, Meeker, D, Pratt, N & Madigan, D 2016, 'Characterizing treatment pathways at scale using the OHDSI network', Proceedings of the National Academy of Sciences of USA, vol. 113, no. 27, pp. 7329-7336. Open access 53 56 168

Journal Articles

Year	Output
2019	Duszynski, KM, Pratt, NL, Lynch, JW, Berry, JG, Gold, MS & Roughead, EE and 24 other authors and 1 consortium 2019, 'Use of different combination diphtheria-tetanus-acellular pertussis vaccines does not increase risk of 30-day infant mortality. A population-based linkage cohort study using administrative data from the Australian Childhood Immunisation Register and the National Death Index.', Vaccine, vol. 37, no. 2, pp. 280-288. 15
2019	Duszynski, KM, Pratt, NL, Lynch, JW, Braunack-Mayer, A, Taylor, LK, Berry, JG, Xafis, V, Buttery, J & Gold, MS 2019, 'Process trumps potential public good: better vaccine safety through linked cross-jurisdictional immunisation data in Australia', Australian and New Zealand Journal of Public Health, vol. 43, no. 5, pp. 496-503. Open access
2019	Gillam, MH, Kerr, M, Pratt, NL, Lim, R & Roughead, EE 2019, 'Mesh use in urogynaecological procedures between 2005 and 2016: an Australian cohort study', Australian and New Zealand Journal of Obstetrics and Gynaecology, vol. 59, no. 1, pp. 105-109. Open access 4
2019	Kalisch Ellett, LM, Pratt, NL, Apajee, J & Roughead, EE 2019, 'Initiation and continuation of antipsychotic medicines in older people following non-psychiatric hospital admission', International Journal of Clinical Pharmacy, online, pp. 1-7.
2019	Kelly, T-L & Pratt, N 2019, 'A note on sample size calculations for cluster randomised crossover trials with a fixed number of clusters', Statistics in Medicine, vol. 38, no. 18, pp. 3342-3345. 1
2019	Kemp-Casey, A, Pratt, N, Ramsay, E & Roughead, EE 2019, 'Using post-market utilisation analysis to support medicines pricing policy: an Australian case study of aflibercept and ranibizumab use', Applied Health Economics and Health Policy, vol. 17, no. 3, pp. 411-417. Open access 1 1 8
2019	Lim, R, Kalisch Ellett, L, Widagdo, I, Pratt, N & Roughead, E 2019, 'Analysis of anticholinergic and sedative medicine effects on physical function, cognitive function, appetite and frailty: a cross-sectional study in Australia', BMJ Open, vol. 9, no. 9, pp. 1-9. Open access
2019	Pratt, NL, Mack, CD, Meyer, AM, Davis, KJ, Hamill, BG, Hampp, C, Setoguchi, S, Raman, SR, Chun, DS, Stürmer, T & Lund, JL 2019, 'Data linkage in pharmacoepidemiology: a call for rigorous evaluation and reporting', Pharmacoepidemiology and Drug Safety, online, pp. 1-9.
2019	Pratt, NL, Ramsay, E, Kalisch Ellett, LM, Duszynski, K, Shakib, S, Kerr, M, Caughey, G & Roughead, EE 2019, 'Comparative effectiveness and safety of low-strength and high-strength direct oral anticoagulants compared with warfarin: a sequential cohort study', BMJ Open, vol.9, no. 5, article no. e026486, pp. 1-11. Open access
2019	Preiss, AK, Roughead, EE & Pratt, NL 2019, 'Sequence symmetry analysis graphic adjustment for prescribing trends', BMC Medical Research Methodology, vol. 19, no. 1, article no.143, pp. 1-12. Open access 1
2019	Rasmussen, L, Pratt, N, Roughead, E & Moffat, A 2019, 'Prevalence of psychotropic medicine use in Australian children with autism spectrum disorder: a drug utilization study based on children enrolled in the Longitudinal Study of Australian Children', Journal of Autism and Developmental Disorders, vol. 49, no. 1, pp. 227–235. 4
2019	Roughead, EE, Lim, R, Ramsay, E, Moffat, A & Pratt, N 2019, 'Persistence with opioids post discharge from hospitalisation for surgery in Australian adults: a retrospective cohort study', BMJ Open, vol. 9, no. 4, article no. e023990, pp. 1-6. Open access 1 31
2019	Westaway, K, Blacker, N, Shute, R, Allin, R, Elgebaly, Z, Frank, O, Pratt, N & Roughead, E 2019, 'Combination psychotropic medicine use in older adults and risk of hip fracture', Australian Prescriber, vol. 42, no. 3, pp. 93-96. Open access 6
2018	Bartlett, LE, Pratt, NL & Roughead, EE 2018, 'Prior experience with cardiovascular medicines predicted longer persistence in people initiated to combinations of antihypertensive and lipid-lowering therapies: findings from two Australian cohorts', Patient Preference and Adherence, vol. 12, pp. 835-843. Open access 1
2018	Gillam, MH, Inacio, MC, Pratt, NL, Shakib, S & Roughead, EE 2018, 'Magnetic resonance imaging in people with cardiac implantable electronic devices: a population based cohort study', Heart Lung and Circulation, vol. 27, pp. 748-751.
2018	Gillam, MH, Pratt, NL, Inacio, MC, Shakib, S, Sanders, P, Lau, DH & Roughead, EE 2018, 'Rehospitalizations for complications and mortality following pacemaker implantation: a retrospective cohort study in an older population', Clinical Cardiology (Hoboken): An Indexed and Peer-Reviewed Journal for Advances in the Treatment of Cardiovascular Disease, vol. 41, no. 11, pp. 1480-1486. Open access 1 1
2018	Hallas, J, Wang, S V, Gagne, JJ, Schneeweiss, S, Pratt, N & Pottegaard, A 2018, 'Hypothesis-free screening of large administrative databases for unsuspected drug-outcome associations', European Journal of Epidemiology, vol. 33, no. 6, pp. 545-555. Open access 3 3 2
2018	Hoang, T, Liu, J, Pratt, N, Zheng, VW, Chang, KC, Roughead, E & Li, J 2018, 'Authenticity and credibility aware detection of adverse drug events from social media', International Journal of Medical Informatics, vol. 120, pp. 101-115.
2018	Hoang, T, Liu, J, Roughead, E, Pratt, N & Li, J 2018, 'Supervised signal detection for adverse drug reactions in medication dispensing data', Computer Methods and Programs in Biomedicine, vol. 161, pp. 25-38. 2 1 2
2018	Inacio, M, Cashman, K, Pratt, N, Gillam, M, Caughey, G, Graves, S & Roughead, E 2018, 'Prevalence and changes in analgesic medication utilisation 1 year prior to total joint replacement in an older cohort of patients', Osteoarthritis and Cartilage, vol. 26, no. 3, pp. 356-362. 8 5
2018	Kalisch Ellett, L, Pratt, N & Roughead, E 2018, 'Analgesic use in Vietnam veterans' with musculoskeletal pain', Journal of Military and Veterans Health, vol. 26, no. 3, pp. 28-35. Open access
2018	Kalisch Ellett, LM, Lim, R, Pratt, NL, Kerr, M, Ramsay, EN, Leblanc, T V, Barratt, JD & Roughead, EE 2018, 'Reducing hypnotic use in insomnia management among Australian veterans: Results from repeated national interventions', BMC Health Services Research, vol.18, no. 1, article no. 626, pp. 1-10. Open access 1 11
2018	Kalisch Ellett, LM, Pratt, NL, Sluggett, JK, Ramsay, EN, Kerr, M, LeBlanc, VT, Barratt, JD, Gilbert, AL & Roughead, EE 2018, 'Sustaining practice change in health care: the impact of a national quality improvement program on the uptake of collaborative medicines reviews', Journal of Pharmacy Practice and Research, vol. 48, no. 3, pp. 222-230. Open access 14
2018	Kassie, GM, Nguyen, TA, Kalisch Ellett, LM, Pratt, NL & Roughead, EE 2018, 'Do risk prediction models for postoperative delirium consider patients' preoperative medication use?', Drugs and Aging, vol. 35, no. 3, pp. 213-222. 1 1 5
2018	Lai, EC-C, Shin, J-Y, Kubota, K, Man, KK, Park, BJ, Pratt, N, Roughead, EE, Wong, IC, Kao Yang, Y-H & Setoguchi, S 2018, 'Comparative safety of NSAIDs for gastrointestinal events in Asia-Pacific populations: a multi-database, international cohort study', Pharmacoepidemiology and Drug Safety, vol. 27, no. 11, pp. 1223-1230.
2018	Nguyen, TA, Pham, T, Vu, HTT, Nguyen, TX, Dang, HT, Kalisch-Ellett, L, Gillam, M, Pratt, N & Roughead, EE and 16 other authors 2018, 'Use of potentially inappropriate medications in people with dementia in Vietnam and its associated factors', American Journal of Alzheimer's Disease and Other Dementias, vol. 33, no. 7, pp. 423-432. 1 1 9
2018	Park, S-K, Baek, Y-H, Pratt, N, Kalisch Ellett, L & Shin, JY 2018, 'The uncertainty of the association between proton pump inhibitor use and the risk of dementia: prescription sequence symmetry analysis using a Korean healthcare database between 2002 and 2013', Drug Safety, vol. 41, no. 6, pp. 615-624. Open access 7 3 3
2018	Pratt, N, Kerr, M, Barratt, J, Kemp-Casey, A, Kalisch Ellett, L, Ramsay, E & Roughead, E 2018, 'The validity of the Rx-Risk Comorbidity Index using medicines mapped to the Anatomical Therapeutic Chemical (ATC) Classification System', BMJ Open, vol. 8, no. 4, pp. 1-8. Open access 14 14 4
2018	Raman, SR, Man, KK, Bahmanyar, S, Berard, A, Pratt, NL, Roughead, EE & Wong, IC and 26 other authors 2018, 'Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases', The Lancet Psychiatry, vol. 5, no. 10, pp. 824-835. Open access 17 16 132
2018	Rasmussen, L, Pratt, N, Hansen, MR, Hallas, J & Pottegård, A 2018, 'Using the 'proportion of patients covered' and the Kaplan-Meier survival analysis to describe treatment persistence', Pharmacoepidemiology and Drug Safety. 1 2
2018	Widagdo, IS, Pratt, NL & Roughead, EE 2018, 'The association between frailty and medicines use over time: an analysis using the Australian Longitudinal Study on Ageing population', Journal of Pharmacy Practice and Research, vol. 48, no. 5, pp. 405-415. 18
2018	Zhan, C, Roughead, E, Liu, L, Pratt, N & Li, J 2018, 'A data-driven method to detect adverse drug events from prescription data', Journal of Biomedical Informatics, vol. 85, pp. 10-20. 2
2017	Bartlett, LE, Pratt, N & Roughead, EE 2017, 'Does a fixed-dose combination of amlodipine and atorvastatin improve persistence with therapy in the Australian population?', Current Medical Research and Opinion, vol. 34, no. 2, pp. 305-311. 1 1 3
2017	Caughey, GE, Pratt, NL, Barratt, JD, Shakib, S, Kemp-Casey, AR & Roughead, EE 2017, 'Understanding 30-day re-admission after hospitalisation of older patients for diabetes: identifying those at greatest risk', Medical Journal of Australia, vol. 206, no. 4, pp. 170-175. Open access 8 7 14
2017	Gadzhanova, S, Pratt, N & Roughead, E 2017, 'Use of SGLT2 inhibitors for diabetes and risk of infection: Analysis using general practice records from the NPS MedicineWise MedicineInsight program', Diabetes Research and Clinical Practice, vol. 130, pp. 180-185. Open access 14 14
2017	Gillam, MH, Pratt, NL, Inacio, MC, Roughead, EE, Shakib, S, Nicholls, SJ & Graves, SE 2017, 'Heart failure after conventional metal-on-metal hip replacements: a retrospective cohort study', Acta Orthopaedica, vol. 88, no. 1, pp. 2-9. Open access 14 13 14
2017	Hansen, CA, Inacio, MC, Pratt, NL, Roughead, EE & Graves, SE 2017, 'Chronic use of opioids before and after total knee arthroplasty: a retrospective cohort study', Journal of Arthroplasty, vol. 32, no. 3, pp. 811-817.e1. 24 26 10
2017	Inacio, MC, Graves, SE, Pratt, NL, Roughead, EE & Nemes, S 2017, 'Increase in total joint arthroplasty projected from 2014 to 2046 in Australia: a conservative local model with international implications', Clinical Orthopaedics and Related Research, vol. 475, no. 8, pp. 2130-2137. Open access 29 23 10
2017	Kalisch Ellett, LM, Pratt, N, Sluggett, J, Ramsay, E, Kerr, M, LeBlanc, V, Barratt, J & Roughead, E 2017, 'Patient-specific prescriber feedback can increase the rate of osteoporosis screening and treatment: results from two national interventions', Archives of Osteoporosis, vol. 12, no. 1, article no. 17, pp. 1-7. Open access 1 1 3
2017	Kalisch Ellett, LM, Pratt, NL, Kerr, M & Roughead, EE 2017, 'Antipsychotic polypharmacy in older Australians', International Psychogeriatrics, vol. 30, no. 4, pp. 539-546. Open access
2017	Kassie, GM, Nguyen, TA, Kalisch Ellett, LM, Pratt, NL & Roughead, EE 2017, 'Preoperative medication use and postoperative delirium: a systematic review', BMC Geriatrics, vol. 17, pp. 1-10. Open access 13 10 14
2017	Lai, EC-C, Pratt, N, Hsieh, C-Y, Lin, S-J, Pottegård, A, Roughead, EE, Kao Yang, Y-H & Hallas, J 2017, 'Sequence symmetry analysis in pharmacovigilance and pharmacoepidemiologic studies', European Journal of Epidemiology, vol. 32, no. 7, pp. 567-582. 15 11 4
2017	Leach, MJ, Pratt, NL & Roughead, EE 2017, 'Risk of hip fracture in older people using selective serotonin reuptake inhibitors and other psychoactive medicines concurrently: A matched case-control study in Australia', Drugs - Real World Outcomes, vol. 4, no. 2, pp. 87-96. Open access 3 6
2017	Leach, MJ, Pratt, NL & Roughead, EE 2017, 'The risk of hip fracture due to mirtazapine exposure when switching antidepressants or using other antidepressants as add-on therapy', Drugs - Real World Outcomes, vol. 4, no. 4, pp. 247-255. Open access 3 6
2017	Namba, RS, Inacio, MC, Pratt, NL, Graves, SE, Roughead, EE & Paxton, EW 2017, 'Persistent opioid use following total knee arthroplasty: a signal for close surveillance', Journal of Arthroplasty, vol. 33, no 2, pp. 331-336. 13 11 9
2017	Pratt, NL, Kalisch Ellett, LM, Sluggett, JK, Gadzhanova, S V, Ramsay, EN, Kerr, M, Leblanc, VT, Barratt, JD & Roughead, EE 2017, 'Use of proton pump inhibitors among older Australians: national quality improvement programmes have led to sustained practice change', International Journal for Quality in Health Care, vol. 29, no. 1 pp. 75-82. 7 5 18
2017	Roughead, EE, Pratt, NL, Kalisch Ellett, LM, Ramsay, EM, Barratt, JD, Morris, P & Killer, G 2017, 'Posttraumatic stress disorder, antipsychotic use and risk of dementia in veterans', Journal of the American Geriatrics Society, vol. 65, no. 7, pp. 1521-1526. Open access 6 4 10
2016	Bartlett, L, Pratt, N & Roughead, EE 2016, 'Does tablet formulation alone improve adherence and persistence: A comparison of ezetimibe fixed dose combination versus ezetimibe separate pill combination?', British Journal of Clinical Pharmacology, vol. 83, no. 1, pp. 202-210. Open access 5 5 2
2016	Hoang, T, Liu, J, Pratt, N, Zheng, VW, Chang, KC, Roughead, E & Li, J 2016, 'Detecting signals of detrimental prescribing cascades from social media', Artificial Intelligence in Medicine, vol. 71, pp. 43-56. 7 7 3
2016	Hripcsak, G, Ryan, PB, Duke, JD, Shah, NH, Park, RW, Huser, V, Suchard, MA, Schuemie, MJ, DeFalco, FJ, Perotte, A, Banda, JM, Reich, CG, Schilling, LM, Matheny, ME, Meeker, D, Pratt, N & Madigan, D 2016, 'Characterizing treatment pathways at scale using the OHDSI network', Proceedings of the National Academy of Sciences of USA, vol. 113, no. 27, pp. 7329-7336. Open access 53 56 168
2016	Inacio, M, Pratt, N & Roughead, E 2016, 'Evaluation of three co-morbidity measures to predict mortality in patients undergoing total joint arthroplasty', Osteoarthritis and Cartilage, vol. 4, pp. 1718-1726. 9 6
2016	Inacio, MC, Hansen, C, Pratt, NL, Graves, SE & Roughead, EE 2016, 'Risk factors for persistent and new chronic opioid use in patients undergoing total hip arthroplasty: a retrospective cohort study', BMJ Open, vol. 6, no. 4, article no. e010664, pp. 1-10. Open access 54 52 1
2016	Inacio, MC, Pratt, NL, Roughead, EE, Paxton, EW & Graves, SE 2016, 'Opioid use after total hip arthroplasty surgery is associated with revision surgery', BMC Musculoskeletal Disorders, vol. 17, article no. 122, pp. 1-9. Open access 16 16 17
2016	Kalisch Ellett, L, Pratt, N, Le, BV, Westaway, K & Roughead, E 2016, 'Increased risk of hospital admission for dehydration or heat-related illness after initiation of medicines: a sequence symmetry analysis', Journal of Clinical Pharmacy and Therapeutics, vol. 41, pp. 503-507. 5 3 20
2016	Kalisch Ellett, LM, Pratt, NL, Ramsay, EN, Sluggett, JK, Barratt, JD & Roughead, EE 2016, 'Central nervous system-acting medicines and risk of hospital admission for confusion, delirium, or dementia', Journal of the American Medical Directors Association, vol. 17, no. 6, pp. 530-534. 2 3 7
2016	Namba, RS, Inacio, MC, Pratt, NL, Graves, SE, Roughead, EE, Cheetham, TC & Paxton, EW 2016, 'Postoperative opioid use as an early indication of total hip arthroplasty failure', Acta Orthopaedica, vol. 87, supplement 1, pp. 37-43. Open access 19 18
2016	Pratt, N, Ramsay, E, Caughey, GE, Shakib, S & Roughead, EE 2016, 'Uptake of novel oral anticoagulants in Australia', Medical Journal of Australia, vol. 204, pp. 104-105. Open access 19 14 1
2016	Roughead, EE, Chan, EW, Choi, N-K, Griffiths, J, Jin, X-M, Lee, J, Kimura, M, Kimura, T, Kubota, K, Lai, EC-C, Man, KK, Nguyen, TA, Ooba, N, Park, B-J, Sato, T, Shin, J-Y, Wang, T, Wong, IC, Yang, Y-HK & Pratt, NL 2016, 'Proton pump inhibitors and risk of Clostridium difficile infection: a multi-country study using sequence symmetry analysis', Expert Opinion on Drug Safety, vol. 15, no. 12, pp. 1589-1595. 13 12 4
2016	Shin, J-Y, Roughead, EE, Park, B-J & Pratt, NL 2016, 'Cardiovascular safety of methylphenidate among children and young people with attention-deficit/hyperactivity disorder (ADHD): nationwide self controlled case series study', BMJ: British Medical Journal, vol. 353, article no. i2550, pp. 1-8. Open access 34 28 265
2016	Wahab, IA, Pratt, NL, Kalisch Ellett, L & Roughead, EE 2016, 'Sequence symmetry analysis as a signal detection tool for potential heart failure adverse events in an administrative claims database', Drug Safety, vol. 39, no. 4, pp. 347-354. 10 10
2016	Widagdo, I, Pratt, N, Russell, M & Roughead, E 2016, 'Construct validity of four frailty measures in an older Australian population: a Rasch analysis', The Journal of Frailty and Aging, vol. 5, no. 2, pp. 78-81. Open access 2 5
2015	Inacio, MC, Pratt, NL, Roughead, EE & Graves, SE 2015, 'Predicting infections after total joint arthroplasty using a prescription based comorbidity measure', Journal of Arthroplasty, vol. 30, no. 10, pp. 1692-1698. Open access 4 3
2015	Inacio, MCS, Pratt, NL, Roughead, EE & Graves, SE 2015, 'Comparing co-morbidities in total joint arthroplasty patients using the RxRisk-V, Elixhauser, and Charlson measures: a cross-sectional evaluation', BMC Musculoskeletal Disorders, vol. 16, no. 1, article no. 385. Open access 5 7 2
2015	Inacio, MCS, Pratt, NL, Roughead, EE & Graves, SE 2015, 'Using medications for prediction of revision after total joint arthroplasty', Journal of Arthroplasty, vol. 30, no. 12, pp. 2061-2070. 4 4 1
2015	Lai, EC-C, Man, KK, Chaiyakunapruk, N, Cheng, C-L, Pratt, N, Roughead, L & Setoguchi, S and 16 other authors 2015, 'Databases in the Asia-Pacific region: the potential for a distributed network approach', Epidemiology, 26, no. 6, pp. 815-820. 20 20
2015	Leach, MJ, Pratt, NL & Roughead, EE 2015, 'Psychoactive medicine use and the risk of hip fracture in older people: a case-crossover study', Pharmacoepidemiology and Drug Safety, vol. 24, no. 6, pp. 576-582. 8 5 8
2015	Nguyen, T, Caughey, G, Pratt, N, Shakib, S, Kemp, A & Roughead, E 2015, 'Hospitalization for drug-induced hepatotoxicity : linking Y-codes with pharmaceutical claims data to identify implicated medicines', Journal of Clinical Pharmacy and Therapeutics, vol. 40, no. 2, pp. 213-219. 2
2015	Pratt, N, Chan, EW, Choi, N-K, Kimura, M, Kimura, T, Kubota, K, Lai, EC-C, Man, KK, Ooba, N, Park, B-J, Sato, T, Shin, J-Y, Wong, IC, Kao, YY-H & Roughead, EE 2015, 'Prescription sequence symmetry analysis: assessing risk, temporality, and consistency for adverse drug reactions across datasets in five countries', Pharmacoepidemiology and Drug Safety, vol. 24, no. 8, pp. 858-864. Open access 10 18 2
2015	Pratt, NL, Kalisch Ellett, LM, Sluggett, JK, Ramsay, EN, Kerr, M, LeBlanc, VT, Barratt, JD & Roughead, EE 2015, 'Commitment questions targeting patients promotes uptake of under-used health services: findings from a national quality improvement program in Australia', Social Science and Medicine, vol. 145, pp. 1-6. 1
2015	Pratt, NL, Ramsay, EN, Kalisch Ellett, LM, Nguyen, TA & Roughead, EE 2015, 'Association between ophthalmic timolol and hospitalisation for bradycardia', Journal of Ophthalmology, vol. 2015, article no. 567387, pp. 1-6. Open access 9 6 10
2015	Roughead, EE & Pratt, NL 2015, 'Impact on drug safety of variation in adherence: the need for routinely reporting measures of dose intensity in medication safety studies using electronic health data', Drug Safety, vol. 38, no. 12, pp. 1145-1152. Open access 1
2015	Roughead, EE, Chan, EW, Choi, N-K, Kimura, M, Kimura, T, Kubota, K, Lai, EC-C, Man, KK, Nguyen, TA, Ooba, N, Park, B-J, Sato, T, Shin, J-Y, Wang, T, Griffiths, J, Wong, IC, Yang, Y-HK & Pratt, N 2015, 'Variation in association between thiazolidinediones and heart failure across ethnic groups: retrospective analysis of large healthcare claims databases in six countries', Drug Safety, vol.38, no. 9, pp. 823-831. Open access 13 13 3
2015	Widagdo, I, Pratt, N, Russell, M & Roughead, L 2015, 'How common is frailty in older Australians?', Australasian Journal on Ageing, vol. 34, no. 4, pp. 247-251. 6 4
2015	Widagdo, IS, Pratt, N, Russell, M & Roughead, EE 2015, 'Predictive performance of four frailty measures in an older Australian population', Age and Ageing, vol. 44, no. 6, pp. 967-972. Open access 13 15 3
2014	Kalisch Ellett, LM, Pratt, NL, Barratt, JD, Rowett, D & Roughead, EE 2014, 'Risk of medication-associated initiation of oxybutynin in elderly men and women', Journal of the American Geriatrics Society, vol. 62, no. 4, pp. 690-695. Open access 10 10 5
2014	Kalisch Ellett, LM, Pratt, NL, Ramsay, EN, Barratt, JD & Roughead, EE 2014, 'Multiple anticholinergic medication use and risk of hospital admission for confusion or dementia', Journal of the American Geriatrics Society, vol. 62, no. 10, pp. 1916-1922. Open access 56 47 10
2014	Pratt, NL, Ilomäki, J, Raymond, C & Roughead, EE 2014, 'The performance of sequence symmetry analysis as a tool for post-market surveillance of newly marketed medicines : a simulation study', BMC Medical Research Methodology, vol. 14, article no. 66. Open access 17 16 1
2014	Pratt, NL, Ramsay, EN, Kalisch Ellett, LM, Nguyen, TA, Barratt, JD & Roughead, EE 2014, 'Association between use of multiple psychoactive medicines and hospitalization for falls : retrospective analysis of a large healthcare claim database', Drug Safety, vol. 37, no. 7, pp. 529-535. Open access 19 16 13
2014	Pratt, NL, Ramsay, EN, Kemp, A, Kalisch Ellett, LM, SHAKIB, S, Caughey, GE, Ryan, P, Graves, S & Roughead, EE 2014, 'Ranibizumab and risk of hospitalisation for ischaemic stroke and myocardial infarction in patients with age-related macular degeneration : a self-controlled case-series analysis', Drug Safety, 37, no. 12, pp. 1021-1027. Open access 11 8 1
2014	Wahab, IA, Pratt, NL, Kalisch, LM & Roughead, EE 2014, 'Comparing time to adverse drug reaction signals in a spontaneous reporting database and a claims database : a case study of rofecoxib-induced myocardial infarction and rosiglitazone-induced heart failure signals in Australia', Drug Safety, vol. 37, no. 1, pp. 53-64. 16 14 2
2013	Anderson, M, Bergman, U, Choi, N-K, Gerhard, T, Huang, C, Jalbert, J, Kimura, M, Kimura, T, Kubota, K, Lai, EC-C, Ooba, N, Park, B-J, Pratt, N, Roughead, EE, Sato, T, Setoguchi, S, Shin, J-Y, Sundstrom, A & Yang, Y-HK 2013, 'The Asian Pharmacoepidemiology Network (AsPEN) : promoting multi-national collaboration for pharmacoepidemiologic research in Asia', Pharmacoepidemiology and Drug Safety, vol. 22, no. 7, pp. 700-704. 30 31 1
2013	Leach, MJ, Pratt, NL & Roughead, EE 2013, 'Medicine use among older Australians before and after hip fracture', Journal of Pharmacy Practice and Research, vol. 43, no. 4, pp. 265-268. 4 6
2013	Pratt, N, Andersen, M, Bergman, U, Choi, N-K, Gerhard, T, Huang, C, Kimura, M, Kimura, T, Kubota, K, Lai, EC-C, Ooba, N, Osby, U, Park, B-J, Sato, T, Shin, J-Y, Sundstrom, A, Yang, Y-HK & Roughead, EE 2013, 'Multi-country rapid adverse drug event assessment : the Asian Pharmacoepidemiology Network (AsPEN) antipsychotic and acute hyperglycaemia study', Pharmacoepidemiology and Drug Safety, vol. 22, no. 8, pp. 915-924. 28 24 1
2013	Ramsay, EN, Pratt, NL, Ryan, P & Roughead, EE 2013, 'Proton pump inhibitors and the risk of pneumonia : a comparison of cohort and self-controlled case series designs', BMC Medical Research Methodology, vol. 13, article no. 82, pp. 1-7. Open access 20 18 19
2013	Wahab, IA, Pratt, NL, Kalisch Ellett, LM & Roughead, EE 2013, 'Sequence symmetry analysis and disproportionality analyses: what percentage of adverse drug reaction do they signal?', Advances in Pharmacoepidemiology & Drug Safety, vol. 2, no. 4, pp. 1-5. Open access
2013	Wahab, IA, Pratt, NL, Kalisch Ellett, LM & Roughead, EE 2013, 'The detection of adverse events in randomized clinical trials : can we really say new medicines are safe?', Current Drug Safety, vol. 8, no. 2, pp. 104-113. 6
2013	Wahab, IA, Pratt, NL, Wiese, MD, Kalisch, LM & Roughead, EE 2013, 'The validity of sequence symmetry analysis (SSA) for adverse drug reaction signal detection', Pharmacoepidemiology and Drug Safety, vol. 22, no. 5, pp. 496-502. 29 31 1
2012	Pratt, NL, Roughead, EE, Salter, A & Ryan, P 2012, 'Choice of observational study design impacts on measurement of antipsychotic risks in the elderly: a systematic review', BMC Medical Research Methodology, vol. 12, article no. 72, pp. 1-19. Open access 34 33 1
2012	Roughead, EE, Kalisch Ellett, LM, Pratt, NL, Killer, G, Barnard, A & Gilbert, AL 2012, 'Managing glaucoma in those with co-morbidity : not as easy as it seems', Ophthalmic Epidemiology, vol. 19, no. 2, pp. 74-82. 17 15 1
2011	Bell, JS, Kalisch Ellett, LM, Ramsay, EN, Pratt, NL, Barratt, JD, Le, BT, Roughead, EE & Gilbert, AL 2011, 'Prescriber feedback to improve quality use of medicines among older people: the veterans' MATES program', Journal of Pharmacy Practice and Research, vol. 41, no. 4, pp. 316-319. 11 3
2011	Caughey, GE, Roughead, EE, Pratt, NL, Killer, G & Gilbert, AL 2011, 'Stroke risk and NSAIDs: an Australian population-based study', Medical Journal of Australia, vol. 195, no. 9, pp. 525-529. Open access 39 34
2011	Costain, D, Whitehouse, S, Pratt, NL, Graves, S, Ryan, P & Crawford, R 2011, 'Perioperative mortality after hemiarthroplasty related to fixation method', Acta Orthopaedica, vol. 82, no. 3, pp. 275-281. Open access 37 32 1
2011	Pratt, N, Roughead, EE, Ramsay, E, Salter, A & Ryan, P 2011, 'Risk of hospitalization for hip fracture and pneumonia associated with antipsychotic prescribing in the elderly: a self-controlled case-series analysis in an Australian health care claims database', Drug Safety, vol. 34, no. 7, pp. 567-575. 49 41 1
2011	Ramsay, EN, Roughead, EE, Ewald, B, Pratt, N & Ryan, P 2011, 'A self-controlled case series to assess the effectiveness of beta blockers for heart failure in reducing hospitalisations in the elderly', BMC Medical Research Methodology, vol. 11, article no. 106. Open access 5 5
2010	Atle Lie, S, Pratt, N, Ryan, P, Engesaeter, L, Havelin, L, Furnes, O & Graves, S 2010, 'Duration of the Increase in Early Postoperative Mortality After Elective Hip and Knee Replacement', Journal of Bone and Joint Surgery: American Volume, vol. 92, no. 1, pp. 58-63. 44 42
2010	Pratt, N, Roughead, EE, Ryan, P & Gilbert, AL 2010, 'Differential impact of NSAIDs on rate of adverse events that require hospitalization in high-risk and general veteran populations: A retrospective cohort study', Drugs and Aging, vol. 27, no. 1, pp. 63-71. 19 14 3
2010	Pratt, N, Roughead, EE, Salter, A & Ryan, P 2010, 'Factors associated with choice of antipsychotic treatment in elderly veterans: potential confounders for observational studies', Australian and New Zealand Journal of Public Health, vol. 34, no. 6, pp. 589-593. 5 5
2010	Roughead, EE, Barratt, JD, Ramsay, E, Pratt, N, Ryan, P, Peck, R, Killer, G & Gilbert, AL 2010, 'Collaborative home medicines review delays time to next hospitalization for warfarin associated bleeding in Australian war veterans', Journal of Clinical Pharmacy and Therapeutics.
2010	Roughead, EE, Ryan, P, Salter, A & Pratt, N 2010, 'Antipsychotics and the risk of death in the elderly: an instrumental variable analysis using two preference based instruments', Pharmacoepidemiology and Drug Safety, vol. 19, no. 7, pp. 699-707. 24 24
2009	Roughead, EE, Barratt, JD, Ramsay, E, Pratt, N, Ryan, P, Peck, R, Killer, G & Gilbert, AL 2009, 'The Effectiveness of Collaborative Medicine Reviews in Delaying Time to Next Hospitalization for Patients With Heart Failure in the Practice Setting', Circulation: Heart Failure, vol. 2, pp. 424-428. Open access 93 70
2009	Roughead, EE, Ramsay, E, Ryan, P, Gilbert, AL & Pratt, N 2009, 'Proton-pump inhibitors and the risk of antibiotic use and hospitalisation for pneumonia', Medical Journal of Australia, vol. 190, no. 3, pp. 114-116. 26 17
2008	Conroy, J, Whitehouse, S, Graves, S, Pratt, N, Ryan, P & Crawford, R 2008, 'Risk Factors for Revision for Early Dislocation in Total Hip Arthroplasty', Journal of Arthroplasty, vol. 23, no. 6, pp. 867-872. 85 74
2008	Roughead, EE, Ramsay, E, Pratt, N & Gilbert, AL 2008, 'NSAID Use in individuals at risk of renal adverse events: An observational study to investigate trends in Australian veterans', Drug Safety, vol. 31, no. 11, pp. 997-1003. Open access 17 15

Reports

Year	Output
2018	Roughead, L, Kemp-Casey, A, Pratt, N & Nguyen, TA 2018, Methods to analyse medicine utilization and expenditure to support pharmaceutical policy implementation, World Health Organisation. Open access

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Advanced Digital Sciences Center	UNITED STATES
Ajou University	KOREA, REPUBLIC OF (SOUTH)
Astellas Pharma	JAPAN
Austin Health	AUSTRALIA
Australian Health Practitioner Regulation Agency	AUSTRALIA
Australian National University	AUSTRALIA
Australian Orthopaedic Association	AUSTRALIA
Bond University	AUSTRALIA
Brigham and Women's Hospital	UNITED STATES
Columbia University	UNITED STATES
Cyberjaya University College of Medical Sciences	MALAYSIA
Department of Health and Ageing	AUSTRALIA
Department of Veterans Affairs	AUSTRALIA
Duke Clinical Research Institute	UNITED STATES
Duke University	UNITED STATES
Flinders University	AUSTRALIA
Food and Drug Administration	UNITED STATES
Hamamatsu University	JAPAN
Harvard University	UNITED STATES
Haukeland University Hospital	NORWAY
Health Canada	CANADA
Helping Hand Aged Care	AUSTRALIA
IMS Health	UNITED STATES
Janssen Research and Development	BELGIUM
Jewish General Hospital	CANADA
Kaiser Permanente	UNITED STATES
Karolinska Institute	SWEDEN
Korea Institute of Drug Safety and Risk Management	KOREA, REPUBLIC OF (SOUTH)
McGill University	CANADA
Ministry of Health	INDIA
Monash University	AUSTRALIA
Monash University Malaysia	MALAYSIA
Murdoch Childrens Research Institute	AUSTRALIA
National Cheng Kung University	TAIWAN
National Geriatric Hospital of Vietnam	VIET NAM
National Institutes of Health	UNITED STATES
NPO Drug Safety Research Unit	JAPAN
NPS MedicineWise	AUSTRALIA
Observational Health Data Sciences and Informatics	UNITED STATES
Odense University Hospital	DENMARK
Parliament House, Canberra	AUSTRALIA
Private Individual	AUSTRALIA
Queensland University of Technology	AUSTRALIA
Royal Adelaide Hospital	AUSTRALIA
Rutgers University	UNITED STATES
Seoul National University	KOREA, REPUBLIC OF (SOUTH)
South Australian Health and Medical Research Institute (SAHMRI)	AUSTRALIA
Southern Cross Care (SA)	AUSTRALIA
Stanford University	UNITED STATES
Sung Kyun Kwan University	KOREA, REPUBLIC OF (SOUTH)
Swedish Hip Arthroplasty Register	SWEDEN
The Prince Charles Hospital	AUSTRALIA
University College London	UNITED KINGDOM
University of Adelaide	AUSTRALIA
University of California, Berkeley	UNITED STATES
University of California, Los Angeles	UNITED STATES
University of Colorado Boulder	UNITED STATES
University of Hong Kong	HONG KONG
University of Illinois at Chicago	UNITED STATES
University of Illinois at Urbana-Champaign	UNITED STATES
University of Melbourne	AUSTRALIA
University of Montreal	CANADA
University of New South Wales	AUSTRALIA
University of Newcastle	AUSTRALIA
University of North Carolina at Chapel Hill	UNITED STATES
University of South Australia	AUSTRALIA
University of Southern California	UNITED STATES
University of Southern Denmark	DENMARK
University of Tasmania	AUSTRALIA
University of Tokyo	JAPAN
University of Western Australia	AUSTRALIA
Vanderbilt University	UNITED STATES
Veterans’ Medicines Advice and Therapeutics Education Services (Veterans’ MATES)	AUSTRALIA
Western Sydney University	AUSTRALIA

External engagement & recognition

Engagement/recognition	Year
Chief Investigator, Centre of Research Excellence National Health and Medical Research Council (NHMRC)	2017
co-chair Asian Pharmacoepidemiology Network (AsPEN	2017
Evaluation Leader, Veterans Medicines Advice and Therapeutics Education Service Department of Veterans Affairs (Veteran MATES), Australian Government	2017
Member International Society for Pharmacoepidemiology	2017
Member Statistical Society of Australia	2017
Member International Society for Environmental Epidemiology	2017
Winnovation Award for Science Women in Innovation	2015
Member, Advisory Committee on the Safety of Medicines Therapeutic Goods Administration, Department of Health, Australian Government	2013
Early Career Fellowship National Health and Medical Research Council (NHMRC)	2012
Early Career Researcher, Best Oral Presentation Health Services Research Association of Australia and New Zealand	2011

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
Developing computational methods for detecting signals of adverse drug events from healthcare data	Current
How do Governments manage uncertainty about pharmaceutical evidence while maintaining a transparent and rigorous decision-making process for public reimbursement of pharmaceuticals?	Current
The prediction of drug-drug interactions in pharmaco-epidemiological databases using in silico molecular modelling techniques.	Current
Using machine learning approaches to predict adverse events of medicines and medical devices	Current
Developing data mining methods for detecting signals of adverse drug events	Completed
Enhancing Australia's pharmaco-surveillance capacity: a validation of sequence symmetry analysis method	Completed
Fixed dose combination medicine use in cardiovascular disease: implications for quality use of medicines and subsidy in Australia	Completed
Medicines and the risk of hip fracture among older people: an investigation of medicine safety in administrative claims data	Completed
Understanding frailty and its association with medicine use	Completed

more less

Associate Professor Nicole Pratt

About me

About me

School of Pharmacy and Medical Sciences

About me

Professional Associations

Experience

Qualifications

Research

Research themes

Research focus

Highlights

Projects

Outputs

Highlights

Journal Articles

Reports

Current research & highlights

External engagement & recognition

Collaborations

Collaborations

External engagement & recognition

Chief Investigator, Centre of Research Excellence

co-chair

Evaluation Leader, Veterans Medicines Advice and Therapeutics Education Service

Member

Member

Member

Winnovation Award for Science

Member, Advisory Committee on the Safety of Medicines

Early Career Fellowship

Early Career Researcher, Best Oral Presentation

Teaching & student supervision

Courses and programs

Research degree supervision

Gallery