Professor Nicole Pratt

Research Professor in Biostatistics & Pharmacoepidemiology UniSA Clinical & Health Sciences

City East Campus (P6-31)
tel +61 8 830 22818

email Nicole.Pratt@unisa.edu.au

Research Degree Supervisor

About me

Professor Nicole Pratt is the Deputy Director of the Quality Use of Medicines and Pharmacy Research Centre, University of South Australia. She is a member of the Drug Utilisation Subcommittee (DUSC) of the Australian Department of Health Pharmaceutical Benefits Advisory Committee (PBAC).

She has a particular interest in new statistical methodologies to study the effectiveness and safety of medicine use and in the development of tools for post-marketing surveillance of medicines.

Nicole leads the evaluation of the Department of Veterans Affairs, Veterans’ Medicines Advice and Therapeutics Education Service (Veterans’ MATES) program which uses administrative claims data to develop and evaluate interventions to improve use ... Read more

UniSA Clinical & Health Sciences

UniSA Clinical & Health Sciences is addressing society’s most critical and emerging health needs through quality teaching, learning and research excellence.

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Research

Research focus

Public Health and Health Services
Clinical Sciences
Medical and Health Sciences
Psychology and Cognitive Sciences
Pharmacology and Pharmaceutical Sciences

Highlights

Pharmacoepidemiology
Statistical Research Methods
Quality Use of Medicines

Research

Projects

Excludes commercial-in-confidence projects.

Large scale evidence generation for the utilisation and safety of biologic medicines, NHMRC - Project Grant, 01/01/2019 - 31/12/2022
CRISTAL: Cluster Randomised Trial of Aspirin versus Low molecular weight heparin for venous thromboembolism prophylaxis in joint replacement surgery, a registry-nested study, MRFF - Clinical Trials and Registries, 01/06/2018 - 31/05/2022
Veterans' Medicines Advice and Therapeutics Education Services (Veterans' MATES) Program, Cwth Dept of Veterans' Affairs, 01/09/2015 - 31/12/2021
Veterans' Medicines Advice and Therapeutics Education Services (Veterans' MATES) Program, Cwth Dept of Veterans' Affairs, 01/09/2015 - 31/12/2021
Utilisation review of prostacyclin analogue medicines for the treatment of pulmonary arterial hypertension (PAH), Cwth Dept of Health, 26/03/2021 - 15/10/2021
ReMinDAR Trial: Reducing medicine induced deterioration and adverse reactions trial, Cwth Dept of Health, 15/09/2017 - 31/03/2021
CVC Mental Health Pilot, Cwth Dept of Veterans' Affairs, 03/01/2018 - 31/12/2020
Enhancing joint replacement outcomes through national data linkage, NHMRC - Project Grant, 01/01/2018 - 31/12/2020
Centre of Research Excellence in post-market surveillance of medicines and medical devices, NHMRC - Centre of Research Excellence, 01/11/2012 - 31/10/2018
Data analytics, evaluation of new and emerging analysis methods, advisory services re data analytics, strategic planning, processess and capability improvements., Cwth Dept of Health, 04/12/2017 - 30/06/2018
Understanding medicine safety, NHMRC - Early Career Fellowship, 26/03/2012 - 25/03/2016
First step of WHO/EMP work for improving medicines use in countries, World Health Organisation Malaysia, 16/11/2015 - 12/02/2016
Medical and advisory services, Therapeutic Goods Administration, 01/01/2014 - 30/12/2015

Research

Outputs

Research outputs for the last seven years are shown below. To see earlier years visit ORCID, ResearcherID or Scopus

Open access indicates that an output is open access.

Highlights

Year	Output
2018	Hallas, J, Wang, S V, Gagne, JJ, Schneeweiss, S, Pratt, N & Pottegaard, A 2018, 'Hypothesis-free screening of large administrative databases for unsuspected drug-outcome associations', European Journal of Epidemiology, vol. 33, no. 6, pp. 545-555. Open access 16 15 2
2018	Pratt, N, Kerr, M, Barratt, J, Kemp-Casey, A, Kalisch Ellett, L, Ramsay, E & Roughead, E 2018, 'The validity of the Rx-Risk Comorbidity Index using medicines mapped to the Anatomical Therapeutic Chemical (ATC) Classification System', BMJ Open, vol. 8, no. 4, pp. 1-8. Open access 93 98 23
2018	Raman, SR, Man, KK, Bahmanyar, S, Berard, A, Pratt, NL, Roughead, EE & Wong, IC and 26 other authors 2018, 'Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases', The Lancet Psychiatry, vol. 5, no. 10, pp. 824-835. Open access 107 108 162
2017	Lai, EC-C, Pratt, N, Hsieh, C-Y, Lin, S-J, Pottegård, A, Roughead, EE, Kao Yang, Y-H & Hallas, J 2017, 'Sequence symmetry analysis in pharmacovigilance and pharmacoepidemiologic studies', European Journal of Epidemiology, vol. 32, no. 7, pp. 567-582. 39 38 3
2016	Hripcsak, G, Ryan, PB, Duke, JD, Shah, NH, Park, RW, Huser, V, Suchard, MA, Schuemie, MJ, DeFalco, FJ, Perotte, A, Banda, JM, Reich, CG, Schilling, LM, Matheny, ME, Meeker, D, Pratt, N & Madigan, D 2016, 'Characterizing treatment pathways at scale using the OHDSI network', Proceedings of the National Academy of Sciences of USA, vol. 113, no. 27, pp. 7329-7336. Open access 142 140 174

Journal Articles

Year	Output
2022	Andrade, AQ, Calabretto, JP, Pratt, NL, Kalisch-Ellett, LM, Kassie, GM, LeBlanc, VT, Ramsay, E & Roughead, EE 2022, 'Implementation and evaluation of a digitally enabled precision public health intervention to reduce inappropriate gabapentinoid prescription: cluster randomized controlled trial', Journal of Medical Internet Research, vol. 24, no. 1, pp. 1-12. Open access 5
2022	Cuthbert, AR, Giles, LC, Glonek, G, Kalisch Ellett, LM & Pratt, NL 2022, 'A comparison of survival models for prediction of eight-year revision risk following total knee and hip arthroplasty', BMC Medical Research Methodology, vol. 22, article no. 164. Open access
2022	Dorj, G, Lim, R, Ellett, LK, Kelly, T-L, Andrade, A, Widagdo, I, Pratt, N, Bilton, R & Roughead, E 2022, 'Medicine-related problems: a recurrent issue among residents living in nursing homes', Frontiers in Pharmacology, vol. 13, pp. 1-9. Open access
2022	Gillam, MH, Pratt, NL, Inacio, MC, Shakib, S, Caughey, GE, Sanders, P, Lau, DH & Roughead, EE 2022, 'Cardiac implantable electronic devices: reoperations and the competing risk of death', Heart Lung and Circulation, vol. 31, no. 4, pp. 537-543.
2022	Hillen, J, Ward, M, Slee, M, Stanford, T, Roughead, E, Kalisch Ellett, L & Pratt, N 2022, 'Utilisation of disease modifying treatment and diversity of treatment pathways in relapsing remitting multiple sclerosis', Multiple Sclerosis and Related Disorders, vol. 57, article no. 103412, pp. 1-8.
2022	Hillen, JB, Stanford, T, Ward, M, Roughead, EE, Kalisch Ellett, L & Pratt, N 2022, 'Rituximab and pyoderma gangrenosum: an investigation of disproportionality using a systems biology-informed approach in the FAERS database', Drugs - Real World Outcomes, online, pp. 1-9. Open access
2022	Jin, X, Gallego Luxan, B, Hanly, M, Pratt, NL, Harris, I, de Steiger, R, Graves, SE & Jorm, L 2022, 'Estimating incidence rates of periprosthetic joint infection after hip and knee arthroplasty for osteoarthritis using linked registry and administrative health data', The Bone and Joint Journal, vol. 104-B, no. 9, pp. 1060-1066. Open access
2022	Kassie, GM, Nguyen, TA, Pratt, NL & Kalisch Ellett, LM 2022, 'The risk of preoperative central nervous system-acting medications on delirium following hip or knee surgery: a matched case-control study', Drug Safety, vol. 45, pp. 75-82. 143
2022	Kelly, T-L, Ward, M, Pratt, NL, Ramsay, E, Gillam, M & Roughead, EE 2022, 'The association between exacerbation of chronic obstructive pulmonary disease and timing of paracetamol use: a cohort study in elderly Australians', Respiratory Research, vol. 23, no. 1, article no.80, pp. 1-11. Open access 9
2022	Pratt, N, Camacho, X, Vajdic, C, Degenhardt, L, Laba, TL, Hillen, J, Etherton-Beer, C, Preen, D, Jorm, L, Donnolley, N, Havard, A & Pearson, SA 2022, 'The Medicines Intelligence Centre of Research Excellence: co-creating real-world evidence to support the evidentiary needs of Australian medicines regulators and payers', International Journal of Population Data Science, vol. 6, no. 3, article no. 09. Open access
2022	Roughead, EE, Kerr, M, Moffat, A, Kassie, GM & Pratt, N 2022, 'Medicine-induced acute kidney injury findings from spontaneous reporting systems, sequence symmetry analysis and a case-control study with a focus on medicines used in primary care', Drug Safety, online, pp. 1-9. Open access
2022	Roughead, EE, Pratt, NL, Parfitt, G, Rowett, D, Kalisch-Ellett, LM, Bereznicki, L, Merlin, T, Corlis, M, Kang, AC, Whitehouse, J, Bilton, R, Schubert, C, Torode, S, Kelly, T-L, Andrade, AQ, Post, D, Dorj, G, Cousins, J, Williams, M & Lim, R 2022, 'Effect of an ongoing pharmacist service to reduce medicine-induced deterioration and adverse reactions in aged-care facilities (nursing homes): a multicentre, randomised controlled trial (the ReMInDAR trial)', Age and Ageing, vol. 51, no. 4, article no. afac092, pp. 1-9. Open access 97
2022	Roughead, EE, Ramsay, E, Kalisch Ellett, L, Khoo, A, Moffatt, A & Pratt, N 2022, 'Variation in health service use by veterans with an accepted disability of post-traumatic stress disorder who had a service record post 1975: a cluster analysis', BMJ Military Health, vol. 168, no. 1, pp. 1-6. Open access 1
2022	Schuemie, MJ, Arshad, F, Pratt, N, Nyberg, F, Alshammari, TM, Hripcsak, G, Ryan, P, Prieto-Alhambra, D, Lai, LY, Li, X, Fortin, S, Minty, E & Suchard, MA 2022, 'Vaccine safety surveillance using routinely collected healthcare data-an empirical evaluation of epidemiological designs', Frontiers in Pharmacology, vol. 13, article no. 893484, pp. 1-11. Open access 5
2022	Sidhu, VS, Kelly, T-L, Pratt, N, Graves, SE & Harris, IA 2022, 'Effect of aspirin vs enoxaparin on symptomatic venous thromboembolism in patients undergoing hip or knee arthroplasty: the CRISTAL randomized trial', JAMA Pediatrics, vol. 328, no. 8, pp. 719-727. Open access
2022	Tong, X, Li, X, Pratt, NL, Hillen, JB, Stanford, T, Ward, M, Roughead, EE, Lai, EC-C, Shin, J-Y, Cheng, FW, Peng, K, Lau, CS, Leung, WK & Wong, IC 2022, 'Monoclonal antibodies and Fc-fusion protein biologic medicines: a multinational cross-sectional investigation of accessibility and affordability in Asia Pacific regions between 2010 and 2020', The Lancet Regional Health. Western Pacific, vol. 26, article no. 100506, pp. 1-12. Open access
2022	Williams, RD, Markus, AF, Yang, C, Duarte-Salles, T, Pratt, N & Rijnbeek, PR and 43 other authors 2022, 'Seek COVER: using a disease proxy to rapidly develop and validate a personalized risk calculator for COVID-19 outcomes in an international network', BMC Medical Research Methodology, vol. 22, article no. 35. Open access
2022	de Steiger, RN, Pratt, NL, Gulyani, A, Duszynski, KM, Inacio, MC, Graves, SE & Smith, PN 2022, 'Antibiotic utilisation in primary and revision total hip replacement patients: A registry linkage cohort study of 106 253 patients using the Australian Orthopaedic Association National Joint Replacement Registry', Pharmacoepidemiology and Drug Safety, online, pp. 1-10. Open access
2021	Chan You, S, Krumholz, HM, Suchard, MA, Schuemie, MJ, Hripcsak, G, Chen, R, Shea, S, Duke, J, Pratt, N, Reich, CG, Madigan, D, Ryan, PB, Woong Park, R & Park, S 2021, 'Comprehensive comparative effectiveness and safety of first-line β-blocker monotherapy in hypertensive patients: a large-scale multicenter observational study', Hypertension, vol. 77, no. 5, pp. 1528-1538. 1 2 21
2021	Chen, RJ, Suchard, MA, Krumholz, HM, Schuemie, MJ, Shea, S, Duke, J, Pratt, N, Reich, CG, Madigan, D, You, SC, Ryan, PB & Hripcsak, G 2021, 'Comparative first-line effectiveness and safety of ACE (Angiotensin-Converting Enzyme) inhibitors and angiotensin receptor blockers: a multinational cohort study', Hypertension, vol. 78, pp. 591-603. 10 9 419
2021	Cuthbert, AR, Graves, SE, Giles, LC, Glonek, G & Pratt, N 2021, 'What is the effect of using a competing-risks estimator when predicting survivorship after joint arthroplasty: a comparison of approaches to survivorship estimation in a large registry', Clinical Orthopaedics and Related Research, vol. 479, no. 2, pp. 392-403. 2 2
2021	Duszynski, KM, Stark, JH, Cohet, C, Huang, WT, Shin, JY, Lai, ECC, Man, KK, Choi, NK, Khromava, A, Kimura, T, Huang, K, Watcharathanakij, S, Kochhar, S, Chen, RT & Pratt, NL 2021, 'Suitability of databases in the Asia-Pacific for collaborative monitoring of vaccine safety', Pharmacoepidemiology and Drug Safety, vol. 30, no. 7, pp. 843-857. 2 2 4
2021	Hallas, J, Whitaker, H, Delaney, JA, Cadarette, SM, Pratt, N & Maclure, M 2021, 'The use of active comparators in self-controlled designs', American Journal of Epidemiology, vol. 190, no. 10, pp. 2181-2187. 6
2021	Kalisch Ellett, LM, Kassie, GM, Caughey, GE, Ramsay, EN, Pratt, NL & Roughead, EE 2021, 'Medication-related hospital admissions in aged care residents', Australasian Journal on Ageing, vol. 40, no. 4, pp. e323-e331. Open access 1 1 9
2021	Kalisch Ellett, LM, Kassie, GM, Ramsay, EN, Pratt, NL & Roughead, EE 2021, 'Evaluation of renal function testing in older Australian veterans dispensed medicines that require renal function monitoring', Drugs and Aging, vol. 38, no. 11, pp. 995-1002. 4
2021	Kerr, M, Graves, S, Duszynski, K, Inacio, M, de Steiger, R, Harris, I, Ackerman, I, Jorm, L, Lorimer, M & Pratt, N 2021, 'Does a prescription-based comorbidity index correlate with the American Society of Anesthesiologists physical status score and mortality after joint arthroplasty? A registry study', Clinical Orthopaedics and Related Research, online, pp. 1-10. 2
2021	Kubota, K, Kelly, T-L, Sato, T, Pratt, N, Roughead, E & Yamaguchi, T 2021, 'A novel weighting method to remove bias from within-subject exposure dependency in case-crossover studies', BMC Medical Research Methodology, vol. 21, no. 1, article no. 214, pp. 1-13. Open access
2021	Leach, MJ, Roughead, EE & Pratt, NL 2021, 'A data visualisation method for assessing exposure misclassification in case-crossover studies: the example of tricyclic antidepressants and the risk of hip fracture in older people', BMC Medical Research Methodology, vol. 21, no. 1, article no. 43, pp. 1-7. Open access 1 2
2021	Li, X, Lai, LYH, Ostropolets, A, Arshad, F, Tan, EH, Casajust, P, Alshammari, TM, Duarte-Salles, T, Minty, EP, Areia, C, Pratt, N, Ryan, PB, Hripcsak, G, Suchard, MA, Schuemie, MJ & Prieto-Alhambra, D 2021, 'Bias, precision and timeliness of historical (background) rate comparison methods for vaccine safety monitoring: an empirical multi-database analysis', Frontiers in Pharmacology, vol. 12, article no. 773875, pp. 1-9. Open access 1 1 14
2021	Morales, DR, Conover, MM, You, SC, Pratt, N & Suchard, MA and 27 other authors 2021, 'Renin-angiotensin system blockers and susceptibility to COVID-19: an international, open science, cohort analysis', The Lancet Digital Health, vol. 3, no. 2, pp. e98-e114. Open access 44 47 153
2021	Park, SH, Jeon, HL, Kim, SC, Hillen, J, Gadzhanova, S, Shin, JY & Pratt, N 2021, 'Utilization of targeted disease-modifying anti-rheumatic drugs (DMARDs) for managing rheumatoid arthritis in the last decade: a two-country comparison', International Journal of Clinical Pharmacology and Therapeutics, vol. 59, no. 10, pp. 639-644.
2021	Pearson, SA, Pratt, N, Costa, JdO, Zoega, H, Laba, TL, Etherton-Beer, C, Sanfilippo, FM, Morgan, A, Ellett, LK, Bruno, C, Kelty, E, Ijzerman, M, Preen, DB, Vajdic, C & Henry, D 2021, 'Generating real-world evidence on the quality use, benefits and safety of medicines in australia: history, challenges and a roadmap for the future', International Journal of Environmental Research and Public Health, vol. 18, no. 24, article no. 13345, pp. 1-20. Open access 6 4 9
2021	Pratt, N, Kalisch Ellett, L, Andrade, A, Le Blanc, V, Barratt, J & Roughead, E 2021, 'Prevalence of multiple risk factors for poor outcomes associated with COVID-19 among an elderly Australian population', Australian Journal of General Practice, vol. 50, no. 1-2, pp. 84-89. Open access 1 1 26
2021	Reps, JM, Rijnbeek, P, Cuthbert, A, Ryan, PB, Pratt, N & Schuemie, M 2021, 'An empirical analysis of dealing with patients who are lost to follow-up when developing prognostic models using a cohort design', BMC Medical Informatics and Decision Making, vol. 21, no. 1, article no. 43, pp. 1-24. Open access 3
2021	Sidhu, VS, Kelly, T-L, Pratt, N, Graves, S, Buchbinder, R, Naylor, J, de Steiger, R, Ackerman, I, Adie, S, Lorimer, M, Bastiras, D, Cashman, K & Harris, I 2021, 'CRISTAL (a cluster-randomised, crossover, non-inferiority trial of aspirin compared to low molecular weight heparin for venous thromboembolism prophylaxis in hip or knee arthroplasty, a registry nested study): statistical analysis plan', Trials, vol. 22 no. 1, article no. 564, pp. 1-14. Open access 2
2020	Andrade, AQ, LeBlanc, VT, Kalisch-Ellett, LM, Pratt, NL, Moffat, A, Blacker, N, Westaway, K, Barratt, JD & Roughead, EE 2020, 'Determinants of usefulness in professional behaviour change interventions: observational study of a 15-year national program', BMJ Open, vol. 10, no. 10, pp. 1-8. Open access 1 1 3
2020	Baek, Y-H, Lee, H, Kim, WJ, Chung, J-E, Pratt, N, Kalisch Ellett, L & Shin, J-Y 2020, 'Uncertain association between benzodiazepine use and the risk of dementia: a cohort study', Journal of the American Medical Directors Association, vol. 21, no. 2, pp. 201-211. 11 10 7
2020	Brauer, R, Wong, ICK, Man, KK, Pratt, NL, Park, RW, Cho, S-Y, Li, Y-C, Iqbal, U, Nguyen, P-AA & Schuemie, M 2020, 'Application of a Common Data Model (CDM) to rank the paediatric user and prescription prevalence of 15 different drug classes in South Korea, Hong Kong, Taiwan, Japan and Australia: an observational, descriptive study', BMJ Open, vol. 10, no. 1, pp. 1-15. Open access 3 3 6
2020	Hripcsak, G, Suchard, MA, Shea, S, Chen, R, You, SC, Pratt, N, Madigan, D, Krumholz, HM, Ryan, PB & Schuemie, MJ 2020, 'Comparison of cardiovascular and safety outcomes of chlorthalidone vs hydrochlorothiazide to treat hypertension', JAMA Internal Medicine, vol. 180, no. 4, pp. 542-551. Open access 50 43 268
2020	Jeon, HL, Byun, SJ, Byun, SJ, Pratt, NL, Sultana, J, Park, SJ & Shin, JY 2020, 'Cardiovascular risk in patients receiving ranibizumab for exudative age-related macular degeneration: a nationwide self-controlled case-series study', British Journal of Ophthalmology, vol. 105, no. 4, pp. 543-548. 4 4 2
2020	Kalisch Ellett, LM, Kemp-Casey, A, Kassie, GM, Pratt, NL & Roughead, EE 2020, 'Use of analgesics following rescheduling of codeine in Australia: an interrupted time series analysis in the veteran population', International Journal of Drug Policy, vol. 81, article no. 102767, pp. 1-7. Open access 3 3 3
2020	Kalisch Ellett, LM, Pratt, NL, Nguyen, TA & Roughead, EE 2020, 'Use of health and support services by people living with dementia in the community setting', Australasian Journal on Ageing, vol. 39, no. 4, pp. 341-349. Open access 3 3 5
2020	King, CE, Pratt, NL, Craig, N, Thai, L, Wilson, M, Nandapalan, N, Kalisch Ellet, L & Behm, EC 2020, 'Detecting medicine safety signals using prescription sequence symmetry analysis of a National Prescribing Data Set', Drug Safety, 43, pp. 787-795. 3 3
2020	Lim, R, Bereznicki, L, Corlis, M, Kalisch Ellett, LM, Kang, AC, Merlin, T, Parfitt, G, Pratt, NL, Rowett, D, Torode, S, Whitehouse, J, Andrade, AQ, Bilton, R, Cousins, J, Kelly, L, Schubert, C, Williams, M & Roughead, EE 2020, 'Reducing medicine-induced deterioration and adverse reactions (ReMInDAR) trial: study protocol for a randomised controlled trial in residential aged-care facilities assessing frailty as the primary outcome', BMJ Open, vol. 10, no. 4, article no. e032851, pp. 1-9. Open access 3 3
2020	Marshall, H, Koehler, A, Wang, B, A'Houre, M, Gold, M, Quinn, H, Crawford, N, Pratt, N, Sullivan, T & Macartney, K 2020, 'Safety of meningococcal B vaccine (4CMenB) in adolescents in Australia', Vaccine, vol. 38, no. 37, pp. 5914-5922. 5 4 6
2020	Moffat, AK, Apajee, J, Pratt, NL, Blacker, N, Le, BVT & Roughead, EE 2020, 'Use of medicines associated with dry mouth and dental visits in an Australian cohort', Australian Dental Journal, vol. 65, no. 3, pp. 189-195. Open access 2 2
2020	Moffat, AK, Pratt, NL, Kalisch Ellett, LM, Ramsay, EN & Roughead, EE 2020, 'Comorbidities in an Australian sample of chronic and new opioid users', Journal of Opioid Management, vol. 16,no. 2, pp. 103-110.
2020	Moffat, AK, Westaway, KP, Apajee, J, Frank, O, Shute, R, Weston, C, Blacker, N, Le Blanc, VT, Kalisch Ellett, LM, Pratt, NL & Roughead, EE 2020, 'Impact of a patient-specific national programme aimed at increasing the use of emollient moisturisers to reduce the risk of skin tears: a longitudinal cohort study', BMJ Open, vol. 10, no. 10, article number e039579, pp. 1-6. Open access
2020	Pratt, NL, Mack, CD, Meyer, AM, Davis, KJ, Hamill, BG, Hampp, C, Setoguchi, S, Raman, SR, Chun, DS, Stürmer, T & Lund, JL 2020, 'Data linkage in pharmacoepidemiology: a call for rigorous evaluation and reporting', Pharmacoepidemiology and Drug Safety, vol. 29, no. 1, pp. 9-17. 8 8 4
2020	Schuemie, M, Ryan, P, Pratt, N, Chen, R, You, S, Krumholz, H, Madigan, D, Hripcsak, G & Suchard, M 2020, 'Principles of Large-scale Evidence Generation and Evaluation across a Network of Databases (LEGEND)', Journal of the American Medical Informatics Association, vol. 27, no. 8, pp. 1331-1337. Open access 11 10 26
2020	Schuemie, MJ, Ryan, PB, Pratt, N, Chen, R, You, SC, Krumholz, HM, Madigan, D, Hripcsak, G & Suchard, MA 2020, 'Large-scale evidence generation and evaluation across a network of databases (LEGEND): assessing validity using hypertension as a case study', Journal of the American Medical Informatics Association, vol. 27, no. 8, pp. 1268-1277. Open access 7 8 13
2020	Zhan, C, Roughead, E, Liu, L, Pratt, N & Li, J 2020, 'Detecting high-quality signals of adverse drug-drug interactions from spontaneous reporting data', Journal of Biomedical Informatics, vol. 112, article no. 103603, pp. 1-13. Open access 1 1 1
2020	Zhan, C, Roughead, E, Liu, L, Pratt, N & Li, J 2020, 'Detecting potential signals of adverse drug events from prescription data', Artificial Intelligence in Medicine, vol. 104, article no. 101839, pp. 1-14. Open access 6 5 2
2019	Duszynski, KM, Pratt, NL, Lynch, JW, Berry, JG, Gold, MS & Roughead, EE and 24 other authors and 1 consortium 2019, 'Use of different combination diphtheria-tetanus-acellular pertussis vaccines does not increase risk of 30-day infant mortality. A population-based linkage cohort study using administrative data from the Australian Childhood Immunisation Register and the National Death Index.', Vaccine, vol. 37, no. 2, pp. 280-288. 2 2 16
2019	Duszynski, KM, Pratt, NL, Lynch, JW, Braunack-Mayer, A, Taylor, LK, Berry, JG, Xafis, V, Buttery, J & Gold, MS 2019, 'Process trumps potential public good: better vaccine safety through linked cross-jurisdictional immunisation data in Australia', Australian and New Zealand Journal of Public Health, vol. 43, no. 5, pp. 496-503. Open access 4 4
2019	Gillam, MH, Kerr, M, Pratt, NL, Lim, R & Roughead, EE 2019, 'Mesh use in urogynaecological procedures between 2005 and 2016: an Australian cohort study', Australian and New Zealand Journal of Obstetrics and Gynaecology, vol. 59, no. 1, pp. 105-109. Open access 3 3 4
2019	Harris, IA, Hatton, A, Pratt, N, Lorimer, M, Naylor, JM, De Steiger, R, Lewis, P & Graves, SE 2019, 'How does mortality risk change over time after hip and knee arthroplasty?', Clinical Orthopaedics and Related Research, vol. 477, no. 6, pp. 1414-1421. Open access 7 6 3
2019	Kalisch Ellett, LM, Kassie, GM, Pratt, NL, Kerr, M & Roughead, EE 2019, 'Prevalence and duration of use of medicines recommended for short-term use in aged care facility residents', Pharmacy, vol. 7, no. 2, pp. 1-11. Open access 3 2
2019	Kalisch Ellett, LM, Moffat, AK, Gadzhanova, S, Pratt, NL, Apajee, J, Woodward, M & Roughead, EE 2019, 'Reduction in use of risperidone for dementia in Australia following changed guidelines', Pharmacy, vol. 7, no. 3, pp. 1-11. Open access 4
2019	Kalisch Ellett, LM, Pratt, NL, Apajee, J & Roughead, EE 2019, 'Initiation and continuation of antipsychotic medicines in older people following non-psychiatric hospital admission', International Journal of Clinical Pharmacy, vol. 41, no. 5, pp. 1341-1347. 2 2
2019	Kelly, T-L & Pratt, N 2019, 'A note on sample size calculations for cluster randomised crossover trials with a fixed number of clusters', Statistics in Medicine, vol. 38, no. 18, pp. 3342-3345. Open access 2 2
2019	Kemp-Casey, A, Pratt, N, Ramsay, E & Roughead, EE 2019, 'Using post-market utilisation analysis to support medicines pricing policy: an Australian case study of aflibercept and ranibizumab use', Applied Health Economics and Health Policy, vol. 17, no. 3, pp. 411-417. Open access 3 3 8
2019	Lim, R, Kalisch Ellett, L, Widagdo, I, Pratt, N & Roughead, E 2019, 'Analysis of anticholinergic and sedative medicine effects on physical function, cognitive function, appetite and frailty: a cross-sectional study in Australia', BMJ Open, vol. 9, no. 9, pp. 1-9. Open access 13 13
2019	Moffat, AK, Pratt, NL, Kerr, M, Kalisch Ellett, LM & Roughead, EE 2019, 'Risk of chronic opioid use in older persons with pre-existing anxiety', Journal of Opioid Management, vol. 16, no. 1, pp. 59-66. 1
2019	Pratt, NL, Ramsay, E, Kalisch Ellett, LM, Duszynski, K, Shakib, S, Kerr, M, Caughey, G & Roughead, EE 2019, 'Comparative effectiveness and safety of low-strength and high-strength direct oral anticoagulants compared with warfarin: a sequential cohort study', BMJ Open, vol.9, no. 5, article no. e026486, pp. 1-11. Open access 7 8
2019	Preiss, AK, Roughead, EE & Pratt, NL 2019, 'Sequence symmetry analysis graphic adjustment for prescribing trends', BMC Medical Research Methodology, vol. 19, no. 1, article no.143, pp. 1-12. Open access 3 2 1
2019	Rasmussen, L, Pratt, N, Roughead, E & Moffat, A 2019, 'Prevalence of psychotropic medicine use in Australian children with autism spectrum disorder: a drug utilization study based on children enrolled in the Longitudinal Study of Australian Children', Journal of Autism and Developmental Disorders, vol. 49, no. 1, pp. 227–235. 6 6 4
2019	Roughead, EE, Lim, R, Ramsay, E, Moffat, A & Pratt, N 2019, 'Persistence with opioids post discharge from hospitalisation for surgery in Australian adults: a retrospective cohort study', BMJ Open, vol. 9, no. 4, article no. e023990, pp. 1-6. Open access 17 16 30
2019	Sidhu, VS, Graves, SE, Buchbinder, R, Naylor, JM, Pratt, NL, de Steiger, RS, Chong, BH, Ackerman, IN, Adie, S, Harris, A, Hansen, A, Cripps, M, Lorimer, M, Webb, S, Clavisi, O, Griffith, EC, Anandan, D, O'Donohue, G, Kelly, T-L & Harris, IA 2019, 'CRISTAL: protocol for a cluster randomised, crossover, non-inferiority trial of aspirin compared to low molecular weight heparin for venous thromboembolism prophylaxis in hip or knee arthroplasty, a registry nested study', BMJ Open, vol. 9, no. 11, article no. e031657, pp. 1-9. Open access 9 9 1
2019	Suchard, MA, Schuemie, MJ, Krumholz, HM, You, SC, Chen, R, Pratt, N, Reich, CG, Duke, J, Madigan, D, Hripcsak, G & Ryan, PB 2019, 'Comprehensive comparative effectiveness and safety of first-line antihypertensive drug classes: a systematic, multinational, large-scale analysis', The Lancet, vol. 394, no. 10211, pp. 1816-1826. Open access 97 102 512
2019	Westaway, K, Blacker, N, Shute, R, Allin, R, Elgebaly, Z, Frank, O, Pratt, N & Roughead, E 2019, 'Combination psychotropic medicine use in older adults and risk of hip fracture', Australian Prescriber, vol. 42, no. 3, pp. 93-96. Open access 2 2 102
2018	Bartlett, LE, Pratt, N & Roughead, EE 2018, 'Does a fixed-dose combination of amlodipine and atorvastatin improve persistence with therapy in the Australian population?', Current Medical Research and Opinion, vol. 34, no. 2, pp. 305-311. 6 6 3
2018	Bartlett, LE, Pratt, NL & Roughead, EE 2018, 'Prior experience with cardiovascular medicines predicted longer persistence in people initiated to combinations of antihypertensive and lipid-lowering therapies: findings from two Australian cohorts', Patient Preference and Adherence, vol. 12, pp. 835-843. Open access 1 2
2018	Gillam, MH, Inacio, MC, Pratt, NL, Shakib, S & Roughead, EE 2018, 'Magnetic resonance imaging in people with cardiac implantable electronic devices: a population based cohort study', Heart Lung and Circulation, vol. 27, pp. 748-751. Open access 4 4
2018	Gillam, MH, Pratt, NL, Inacio, MC, Shakib, S, Sanders, P, Lau, DH & Roughead, EE 2018, 'Rehospitalizations for complications and mortality following pacemaker implantation: a retrospective cohort study in an older population', Clinical Cardiology (Hoboken): An Indexed and Peer-Reviewed Journal for Advances in the Treatment of Cardiovascular Disease, vol. 41, no. 11, pp. 1480-1486. Open access 7 7 1
2018	Hallas, J, Wang, S V, Gagne, JJ, Schneeweiss, S, Pratt, N & Pottegaard, A 2018, 'Hypothesis-free screening of large administrative databases for unsuspected drug-outcome associations', European Journal of Epidemiology, vol. 33, no. 6, pp. 545-555. Open access 16 15 2
2018	Hoang, T, Liu, J, Pratt, N, Zheng, VW, Chang, KC, Roughead, E & Li, J 2018, 'Authenticity and credibility aware detection of adverse drug events from social media', International Journal of Medical Informatics, vol. 120, pp. 157-171. Open access 3 3 1
2018	Hoang, T, Liu, J, Roughead, E, Pratt, N & Li, J 2018, 'Supervised signal detection for adverse drug reactions in medication dispensing data', Computer Methods and Programs in Biomedicine, vol. 161, pp. 25-38. Open access 14 13 2
2018	Inacio, M, Cashman, K, Pratt, N, Gillam, M, Caughey, G, Graves, S & Roughead, E 2018, 'Prevalence and changes in analgesic medication utilisation 1 year prior to total joint replacement in an older cohort of patients', Osteoarthritis and Cartilage, vol. 26, no. 3, pp. 356-362. Open access 14 15 1
2018	Kalisch Ellett, L, Pratt, N & Roughead, E 2018, 'Analgesic use in Vietnam veterans' with musculoskeletal pain', Journal of Military and Veterans Health, vol. 26, no. 3, pp. 28-35. Open access 1
2018	Kalisch Ellett, LM, Lim, R, Pratt, NL, Kerr, M, Ramsay, EN, Leblanc, T V, Barratt, JD & Roughead, EE 2018, 'Reducing hypnotic use in insomnia management among Australian veterans: Results from repeated national interventions', BMC Health Services Research, vol.18, no. 1, article no. 626, pp. 1-10. Open access 3 3 11
2018	Kalisch Ellett, LM, Pratt, NL, Kerr, M & Roughead, EE 2018, 'Antipsychotic polypharmacy in older Australians', International Psychogeriatrics, vol. 30, no. 4, pp. 539-546. Open access 2 2
2018	Kalisch Ellett, LM, Pratt, NL, Sluggett, JK, Ramsay, EN, Kerr, M, LeBlanc, VT, Barratt, JD, Gilbert, AL & Roughead, EE 2018, 'Sustaining practice change in health care: the impact of a national quality improvement program on the uptake of collaborative medicines reviews', Journal of Pharmacy Practice and Research, vol. 48, no. 3, pp. 222-230. Open access 6 14
2018	Kassie, GM, Nguyen, TA, Kalisch Ellett, LM, Pratt, NL & Roughead, EE 2018, 'Do risk prediction models for postoperative delirium consider patients' preoperative medication use?', Drugs and Aging, vol. 35, no. 3, pp. 213-222. 4 4 7
2018	Lai, EC-C, Shin, J-Y, Kubota, K, Man, KK, Park, BJ, Pratt, N, Roughead, EE, Wong, IC, Kao Yang, Y-H & Setoguchi, S 2018, 'Comparative safety of NSAIDs for gastrointestinal events in Asia-Pacific populations: a multi-database, international cohort study', Pharmacoepidemiology and Drug Safety, vol. 27, no. 11, pp. 1223-1230. Open access 5 5
2018	Namba, RS, Inacio, MC, Pratt, NL, Graves, SE, Roughead, EE & Paxton, EW 2018, 'Persistent opioid use following total knee arthroplasty: a signal for close surveillance', Journal of Arthroplasty, vol. 33, no 2, pp. 331-336. 42 39 10
2018	Nguyen, TA, Pham, T, Vu, HTT, Nguyen, TX, Dang, HT, Kalisch-Ellett, L, Gillam, M, Pratt, N & Roughead, EE and 16 other authors 2018, 'Use of potentially inappropriate medications in people with dementia in Vietnam and its associated factors', American Journal of Alzheimer's Disease and Other Dementias, vol. 33, no. 7, pp. 423-432. Open access 4 4 9
2018	Park, S-K, Baek, Y-H, Pratt, N, Kalisch Ellett, L & Shin, JY 2018, 'The uncertainty of the association between proton pump inhibitor use and the risk of dementia: prescription sequence symmetry analysis using a Korean healthcare database between 2002 and 2013', Drug Safety, vol. 41, no. 6, pp. 615-624. Open access 16 14 3
2018	Pratt, N & Roughead, E 2018, 'Assessment of medication safety using only dispensing data', Current Epidemiological Reports, vol. 5, no. 4, pp. 357-369. Open access 7
2018	Pratt, N, Kerr, M, Barratt, J, Kemp-Casey, A, Kalisch Ellett, L, Ramsay, E & Roughead, E 2018, 'The validity of the Rx-Risk Comorbidity Index using medicines mapped to the Anatomical Therapeutic Chemical (ATC) Classification System', BMJ Open, vol. 8, no. 4, pp. 1-8. Open access 93 98 23
2018	Raman, SR, Man, KK, Bahmanyar, S, Berard, A, Pratt, NL, Roughead, EE & Wong, IC and 26 other authors 2018, 'Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases', The Lancet Psychiatry, vol. 5, no. 10, pp. 824-835. Open access 107 108 162
2018	Rasmussen, L, Pratt, N, Hansen, MR, Hallas, J & Pottegård, A 2018, 'Using the 'proportion of patients covered' and the Kaplan-Meier survival analysis to describe treatment persistence', Pharmacoepidemiology and Drug Safety, vol. 27, no. 8, pp. 867-871. Open access 15 16
2018	Widagdo, IS, Pratt, NL & Roughead, EE 2018, 'The association between frailty and medicines use over time: an analysis using the Australian Longitudinal Study on Ageing population', Journal of Pharmacy Practice and Research, vol. 48, no. 5, pp. 405-415. Open access 18
2018	Zhan, C, Roughead, E, Liu, L, Pratt, N & Li, J 2018, 'A data-driven method to detect adverse drug events from prescription data', Journal of Biomedical Informatics, vol. 85, pp. 10-20. Open access 7 5 2
2017	Bartlett, L, Pratt, N & Roughead, EE 2017, 'Does tablet formulation alone improve adherence and persistence: A comparison of ezetimibe fixed dose combination versus ezetimibe separate pill combination?', British Journal of Clinical Pharmacology, vol. 83, no. 1, pp. 202-210. Open access 12 12 8
2017	Caughey, GE, Pratt, NL, Barratt, JD, Shakib, S, Kemp-Casey, AR & Roughead, EE 2017, 'Understanding 30-day re-admission after hospitalisation of older patients for diabetes: identifying those at greatest risk', Medical Journal of Australia, vol. 206, no. 4, pp. 170-175. Open access 15 14 14
2017	Gadzhanova, S, Pratt, N & Roughead, E 2017, 'Use of SGLT2 inhibitors for diabetes and risk of infection: Analysis using general practice records from the NPS MedicineWise MedicineInsight program', Diabetes Research and Clinical Practice, vol. 130, pp. 180-185. Open access 34 34 1
2017	Gillam, MH, Pratt, NL, Inacio, MC, Roughead, EE, Shakib, S, Nicholls, SJ & Graves, SE 2017, 'Heart failure after conventional metal-on-metal hip replacements: a retrospective cohort study', Acta Orthopaedica, vol. 88, no. 1, pp. 2-9. Open access 18 18 14
2017	Hansen, CA, Inacio, MC, Pratt, NL, Roughead, EE & Graves, SE 2017, 'Chronic use of opioids before and after total knee arthroplasty: a retrospective cohort study', Journal of Arthroplasty, vol. 32, no. 3, pp. 811-817.e1. 69 73 10
2017	Inacio, MC, Graves, SE, Pratt, NL, Roughead, EE & Nemes, S 2017, 'Increase in total joint arthroplasty projected from 2014 to 2046 in Australia: a conservative local model with international implications', Clinical Orthopaedics and Related Research, vol. 475, no. 8, pp. 2130-2137. Open access 89 86 11
2017	Kalisch Ellett, LM, Pratt, N, Sluggett, J, Ramsay, E, Kerr, M, LeBlanc, V, Barratt, J & Roughead, E 2017, 'Patient-specific prescriber feedback can increase the rate of osteoporosis screening and treatment: results from two national interventions', Archives of Osteoporosis, vol. 12, no. 1, article no. 17, pp. 1-7. Open access 5 5 2
2017	Kassie, GM, Nguyen, TA, Kalisch Ellett, LM, Pratt, NL & Roughead, EE 2017, 'Preoperative medication use and postoperative delirium: a systematic review', BMC Geriatrics, vol. 17, article no. 298, pp. 1-10. Open access 43 44 19
2017	Lai, EC-C, Pratt, N, Hsieh, C-Y, Lin, S-J, Pottegård, A, Roughead, EE, Kao Yang, Y-H & Hallas, J 2017, 'Sequence symmetry analysis in pharmacovigilance and pharmacoepidemiologic studies', European Journal of Epidemiology, vol. 32, no. 7, pp. 567-582. 39 38 3
2017	Leach, MJ, Pratt, NL & Roughead, EE 2017, 'Risk of hip fracture in older people using selective serotonin reuptake inhibitors and other psychoactive medicines concurrently: A matched case-control study in Australia', Drugs - Real World Outcomes, vol. 4, no. 2, pp. 87-96. Open access 10 6
2017	Leach, MJ, Pratt, NL & Roughead, EE 2017, 'The risk of hip fracture due to mirtazapine exposure when switching antidepressants or using other antidepressants as add-on therapy', Drugs - Real World Outcomes, vol. 4, no. 4, pp. 247-255. Open access 9 6
2017	Pratt, N & Roughead, E 2017, 'Can we reduce the prevalence of persistent opioid use after surgery by predicting the future?', Anaesthesia and Intensive Care. 1 1
2017	Pratt, NL, Kalisch Ellett, LM, Sluggett, JK, Gadzhanova, S V, Ramsay, EN, Kerr, M, Leblanc, VT, Barratt, JD & Roughead, EE 2017, 'Use of proton pump inhibitors among older Australians: national quality improvement programmes have led to sustained practice change', International Journal for Quality in Health Care, vol. 29, no. 1 pp. 75-82. Open access 17 17 18
2017	Roughead, EE, Pratt, NL, Kalisch Ellett, LM, Ramsay, EM, Barratt, JD, Morris, P & Killer, G 2017, 'Posttraumatic stress disorder, antipsychotic use and risk of dementia in veterans', Journal of the American Geriatrics Society, vol. 65, no. 7, pp. 1521-1526. Open access 14 14 9
2016	Hoang, T, Liu, J, Pratt, N, Zheng, VW, Chang, KC, Roughead, E & Li, J 2016, 'Detecting signals of detrimental prescribing cascades from social media', Artificial Intelligence in Medicine, vol. 71, pp. 43-56. Open access 11 10 3
2016	Hripcsak, G, Ryan, PB, Duke, JD, Shah, NH, Park, RW, Huser, V, Suchard, MA, Schuemie, MJ, DeFalco, FJ, Perotte, A, Banda, JM, Reich, CG, Schilling, LM, Matheny, ME, Meeker, D, Pratt, N & Madigan, D 2016, 'Characterizing treatment pathways at scale using the OHDSI network', Proceedings of the National Academy of Sciences of USA, vol. 113, no. 27, pp. 7329-7336. Open access 142 140 174
2016	Inacio, M, Pratt, N & Roughead, E 2016, 'Evaluation of three co-morbidity measures to predict mortality in patients undergoing total joint arthroplasty', Osteoarthritis and Cartilage, vol. 4, no. 10, pp. 1718-1726. Open access 19 18
2016	Inacio, M, Pratt, N, Roughead, E & Graves, S 2016, 'Response to Letter to the Editor: 'use of preoperative comorbidity scores to predict mortality after total arthroplasty'', Osteoarthritis and Cartilage, vol. 25, no. 1, pp. e7. Open access
2016	Inacio, MC, Hansen, C, Pratt, NL, Graves, SE & Roughead, EE 2016, 'Risk factors for persistent and new chronic opioid use in patients undergoing total hip arthroplasty: a retrospective cohort study', BMJ Open, vol. 6, no. 4, article no. e010664, pp. 1-10. Open access 120 122 1
2016	Inacio, MC, Pratt, NL, Roughead, EE, Paxton, EW & Graves, SE 2016, 'Opioid use after total hip arthroplasty surgery is associated with revision surgery', BMC Musculoskeletal Disorders, vol. 17, article no. 122, pp. 1-9. Open access 35 33 17
2016	Kalisch Ellett, L, Pratt, N, Le, BV, Westaway, K & Roughead, E 2016, 'Increased risk of hospital admission for dehydration or heat-related illness after initiation of medicines: a sequence symmetry analysis', Journal of Clinical Pharmacy and Therapeutics, vol. 41, pp. 503-507. 13 9 29
2016	Kalisch Ellett, LM, Pratt, NL, Ramsay, EN, Sluggett, JK, Barratt, JD & Roughead, EE 2016, 'Central nervous system-acting medicines and risk of hospital admission for confusion, delirium, or dementia', Journal of the American Medical Directors Association, vol. 17, no. 6, pp. 530-534. 4 4 7
2016	Namba, RS, Inacio, MC, Pratt, NL, Graves, SE, Roughead, EE, Cheetham, TC & Paxton, EW 2016, 'Postoperative opioid use as an early indication of total hip arthroplasty failure', Acta Orthopaedica, vol. 87, supplement 1, pp. 37-43. Open access 30 29
2016	Pratt, N, Ramsay, E, Caughey, GE, Shakib, S & Roughead, EE 2016, 'Uptake of novel oral anticoagulants in Australia', Medical Journal of Australia, vol. 204, no. 3, pp. 104-105. Open access 29 14 1
2016	Roughead, EE, Chan, EW, Choi, N-K, Griffiths, J, Jin, X-M, Lee, J, Kimura, M, Kimura, T, Kubota, K, Lai, EC-C, Man, KK, Nguyen, TA, Ooba, N, Park, B-J, Sato, T, Shin, J-Y, Wang, T, Wong, IC, Yang, Y-HK & Pratt, NL 2016, 'Proton pump inhibitors and risk of Clostridium difficile infection: a multi-country study using sequence symmetry analysis', Expert Opinion on Drug Safety, vol. 15, no. 12, pp. 1589-1595. Open access 23 22 4
2016	Shin, J-Y, Roughead, EE, Park, B-J & Pratt, NL 2016, 'Cardiovascular safety of methylphenidate among children and young people with attention-deficit/hyperactivity disorder (ADHD): nationwide self controlled case series study', BMJ: British Medical Journal, vol. 353, article no. i2550, pp. 1-8. Open access 74 66 266
2016	Wahab, IA, Pratt, NL, Kalisch Ellett, L & Roughead, EE 2016, 'Sequence symmetry analysis as a signal detection tool for potential heart failure adverse events in an administrative claims database', Drug Safety, vol. 39, no. 4, pp. 347-354. 15 15
2016	Widagdo, I, Pratt, N, Russell, M & Roughead, E 2016, 'Construct validity of four frailty measures in an older Australian population: a Rasch analysis', The Journal of Frailty and Aging, vol. 5, no. 2, pp. 78-81. Open access 2 9
2015	Hripcsak, G, Duke, JD, Shah, NH, Reich, CG, Huser, V, Schuemie, MJ, Suchard, MA, Park, RW, Wong, ICK, Lei, Jvd, Rijnbeekj, PR, Pratt, N, Norén, GN, Li, Y-C, Stang, PE, Madigan, D & Ryan, PB 2015, 'Observational Health Data Sciences and Informatics (OHDSI): opportunities for observational researchers', Studies in Health Technology and Informatics, vol. 216, pp. 574-578. Open access 464 433
2015	Inacio, MC, Pratt, NL, Roughead, EE & Graves, SE 2015, 'Predicting infections after total joint arthroplasty using a prescription based comorbidity measure', Journal of Arthroplasty, vol. 30, no. 10, pp. 1692-1698. Open access 8 7
2015	Inacio, MCS, Pratt, NL, Roughead, EE & Graves, SE 2015, 'Comparing co-morbidities in total joint arthroplasty patients using the RxRisk-V, Elixhauser, and Charlson measures: a cross-sectional evaluation', BMC Musculoskeletal Disorders, vol. 16, no. 1, article no. 385. Open access 20 20 2
2015	Inacio, MCS, Pratt, NL, Roughead, EE & Graves, SE 2015, 'Using medications for prediction of revision after total joint arthroplasty', Journal of Arthroplasty, vol. 30, no. 12, pp. 2061-2070. 8 8 1
2015	Kalisch Ellett, LM, Pratt, NL, Ramsay, EN, Barratt, JD & Roughead, EE 2015, 'Response to lertxundi and colleagues', Journal of the American Geriatrics Society, vol. 63, no. 5, pp. 1054-1055.
2015	Lai, EC-C, Man, KK, Chaiyakunapruk, N, Cheng, C-L, Pratt, N, Roughead, L & Setoguchi, S and 16 other authors 2015, 'Databases in the Asia-Pacific region: the potential for a distributed network approach', Epidemiology, 26, no. 6, pp. 815-820. Open access 40 40
2015	Leach, MJ, Pratt, NL & Roughead, EE 2015, 'Psychoactive medicine use and the risk of hip fracture in older people: a case-crossover study', Pharmacoepidemiology and Drug Safety, vol. 24, no. 6, pp. 576-582. 14 12 8
2015	Nguyen, T, Caughey, G, Pratt, N, Shakib, S, Kemp, A & Roughead, E 2015, 'Hospitalization for drug-induced hepatotoxicity : linking Y-codes with pharmaceutical claims data to identify implicated medicines', Journal of Clinical Pharmacy and Therapeutics, vol. 40, no. 2, pp. 213-219. 1 1 2
2015	Pratt, N, Chan, EW, Choi, N-K, Kimura, M, Kimura, T, Kubota, K, Lai, EC-C, Man, KK, Ooba, N, Park, B-J, Sato, T, Shin, J-Y, Wong, IC, Kao, YY-H & Roughead, EE 2015, 'Prescription sequence symmetry analysis: assessing risk, temporality, and consistency for adverse drug reactions across datasets in five countries', Pharmacoepidemiology and Drug Safety, vol. 24, no. 8, pp. 858-864. Open access 10 34 5
2015	Pratt, NL, Kalisch Ellett, LM, Sluggett, JK, Ramsay, EN, Kerr, M, LeBlanc, VT, Barratt, JD & Roughead, EE 2015, 'Commitment questions targeting patients promotes uptake of under-used health services: findings from a national quality improvement program in Australia', Social Science and Medicine, vol. 145, pp. 1-6. 4 4 1
2015	Pratt, NL, Ramsay, EN, Kalisch Ellett, LM, Nguyen, TA & Roughead, EE 2015, 'Association between ophthalmic timolol and hospitalisation for bradycardia', Journal of Ophthalmology, vol. 2015, article no. 567387, pp. 1-6. Open access 13 10 10
2015	Roughead, EE & Pratt, NL 2015, 'Impact on drug safety of variation in adherence: the need for routinely reporting measures of dose intensity in medication safety studies using electronic health data', Drug Safety, vol. 38, no. 12, pp. 1145-1152. Open access 1 1
2015	Roughead, EE, Chan, EW, Choi, N-K, Kimura, M, Kimura, T, Kubota, K, Lai, EC-C, Man, KK, Nguyen, TA, Ooba, N, Park, B-J, Sato, T, Shin, J-Y, Wang, T, Griffiths, J, Wong, IC, Yang, Y-HK & Pratt, N 2015, 'Variation in association between thiazolidinediones and heart failure across ethnic groups: retrospective analysis of large healthcare claims databases in six countries', Drug Safety, vol.38, no. 9, pp. 823-831. Open access 27 26 3
2015	Widagdo, I, Pratt, N, Russell, M & Roughead, L 2015, 'How common is frailty in older Australians?', Australasian Journal on Ageing, vol. 34, no. 4, pp. 247-251. 13 10
2015	Widagdo, IS, Pratt, N, Russell, M & Roughead, EE 2015, 'Predictive performance of four frailty measures in an older Australian population', Age and Ageing, vol. 44, no. 6, pp. 967-972. Open access 20 21 3
2014	Kalisch Ellett, LM, Pratt, NL, Barratt, JD, Rowett, D & Roughead, EE 2014, 'Risk of medication-associated initiation of oxybutynin in elderly men and women', Journal of the American Geriatrics Society, vol. 62, no. 4, pp. 690-695. Open access 16 16 3
2014	Kalisch Ellett, LM, Pratt, NL, Ramsay, EN, Barratt, JD & Roughead, EE 2014, 'Multiple anticholinergic medication use and risk of hospital admission for confusion or dementia', Journal of the American Geriatrics Society, vol. 62, no. 10, pp. 1916-1922. Open access 81 72 10
2014	Pratt, NL, Ilomäki, J, Raymond, C & Roughead, EE 2014, 'The performance of sequence symmetry analysis as a tool for post-market surveillance of newly marketed medicines : a simulation study', BMC Medical Research Methodology, vol. 14, article no. 66. Open access 24 22 1
2014	Pratt, NL, Ramsay, EN, Kalisch Ellett, LM, Nguyen, TA, Barratt, JD & Roughead, EE 2014, 'Association between use of multiple psychoactive medicines and hospitalization for falls : retrospective analysis of a large healthcare claim database', Drug Safety, vol. 37, no. 7, pp. 529-535. Open access 27 25 13
2014	Pratt, NL, Ramsay, EN, Kemp, A, Kalisch Ellett, LM, SHAKIB, S, Caughey, GE, Ryan, P, Graves, S & Roughead, EE 2014, 'Ranibizumab and risk of hospitalisation for ischaemic stroke and myocardial infarction in patients with age-related macular degeneration : a self-controlled case-series analysis', Drug Safety, 37, no. 12, pp. 1021-1027. Open access 16 12 4
2014	Wahab, IA, Pratt, NL, Kalisch, LM & Roughead, EE 2014, 'Comparing time to adverse drug reaction signals in a spontaneous reporting database and a claims database : a case study of rofecoxib-induced myocardial infarction and rosiglitazone-induced heart failure signals in Australia', Drug Safety, vol. 37, no. 1, pp. 53-64. 23 23 2
2013	Anderson, M, Bergman, U, Choi, N-K, Gerhard, T, Huang, C, Jalbert, J, Kimura, M, Kimura, T, Kubota, K, Lai, EC-C, Ooba, N, Park, B-J, Pratt, N, Roughead, EE, Sato, T, Setoguchi, S, Shin, J-Y, Sundstrom, A & Yang, Y-HK 2013, 'The Asian Pharmacoepidemiology Network (AsPEN) : promoting multi-national collaboration for pharmacoepidemiologic research in Asia', Pharmacoepidemiology and Drug Safety, vol. 22, no. 7, pp. 700-704. 53 48 4
2013	Leach, MJ, Pratt, NL & Roughead, EE 2013, 'Medicine use among older Australians before and after hip fracture', Journal of Pharmacy Practice and Research, vol. 43, no. 4, pp. 265-268. 5 6
2013	Pratt, N, Andersen, M, Bergman, U, Choi, N-K, Gerhard, T, Huang, C, Kimura, M, Kimura, T, Kubota, K, Lai, EC-C, Ooba, N, Osby, U, Park, B-J, Sato, T, Shin, J-Y, Sundstrom, A, Yang, Y-HK & Roughead, EE 2013, 'Multi-country rapid adverse drug event assessment : the Asian Pharmacoepidemiology Network (AsPEN) antipsychotic and acute hyperglycaemia study', Pharmacoepidemiology and Drug Safety, vol. 22, no. 8, pp. 915-924. 41 35 4
2013	Ramsay, EN, Pratt, NL, Ryan, P & Roughead, EE 2013, 'Proton pump inhibitors and the risk of pneumonia : a comparison of cohort and self-controlled case series designs', BMC Medical Research Methodology, vol. 13, article no. 82, pp. 1-7. Open access 21 20 19
2013	Roughead, EE, Kalisch Ellett, LM, Ramsay, EN, Pratt, NL, Barratt, JD, Le, BVT, Ryan, P, Peck, R, Killer, G & Gilbert, AL 2013, 'Bridging evidence-practice gaps: improving use of medicines in elderly Australian veterans', BMC Health Services Research, vol. 13, article no. 514, pp. 1-14. Open access 25 26 4
2013	Wahab, IA, Pratt, NL, Kalisch Ellett, LM & Roughead, EE 2013, 'Sequence symmetry analysis and disproportionality analyses: what percentage of adverse drug reaction do they signal?', Advances in Pharmacoepidemiology & Drug Safety, vol. 2, no. 4, pp. 1-5. Open access
2013	Wahab, IA, Pratt, NL, Kalisch Ellett, LM & Roughead, EE 2013, 'The detection of adverse events in randomized clinical trials : can we really say new medicines are safe?', Current Drug Safety, vol. 8, no. 2, pp. 104-113. 10 11 1
2013	Wahab, IA, Pratt, NL, Wiese, MD, Kalisch, LM & Roughead, EE 2013, 'The validity of sequence symmetry analysis (SSA) for adverse drug reaction signal detection', Pharmacoepidemiology and Drug Safety, vol. 22, no. 5, pp. 496-502. 48 46 4
2012	Pratt, NL, Roughead, EE, Salter, A & Ryan, P 2012, 'Choice of observational study design impacts on measurement of antipsychotic risks in the elderly: a systematic review', BMC Medical Research Methodology, vol. 12, article no. 72, pp. 1-19. Open access 38 35 1
2012	Roughead, EE, Kalisch Ellett, LM, Pratt, NL, Killer, G, Barnard, A & Gilbert, AL 2012, 'Managing glaucoma in those with co-morbidity : not as easy as it seems', Ophthalmic Epidemiology, vol. 19, no. 2, pp. 74-82. 24 19 1
2011	Bell, JS, Kalisch Ellett, LM, Ramsay, EN, Pratt, NL, Barratt, JD, Le, BT, Roughead, EE & Gilbert, AL 2011, 'Prescriber feedback to improve quality use of medicines among older people: the veterans' MATES program', Journal of Pharmacy Practice and Research, vol. 41, no. 4, pp. 316-319. Open access 11
2011	Caughey, GE, Roughead, EE, Pratt, NL, Killer, G & Gilbert, AL 2011, 'Stroke risk and NSAIDs: an Australian population-based study', Medical Journal of Australia, vol. 195, no. 9, pp. 525-529. Open access 45 37
2011	Costain, D, Whitehouse, S, Pratt, NL, Graves, S, Ryan, P & Crawford, R 2011, 'Perioperative mortality after hemiarthroplasty related to fixation method', Acta Orthopaedica, vol. 82, no. 3, pp. 275-281. Open access 59 55
2011	Pratt, N, Roughead, EE, Ramsay, E, Salter, A & Ryan, P 2011, 'Risk of hospitalization for hip fracture and pneumonia associated with antipsychotic prescribing in the elderly: a self-controlled case-series analysis in an Australian health care claims database', Drug Safety, vol. 34, no. 7, pp. 567-575. 61 55
2011	Ramsay, EN, Roughead, EE, Ewald, B, Pratt, N & Ryan, P 2011, 'A self-controlled case series to assess the effectiveness of beta blockers for heart failure in reducing hospitalisations in the elderly', BMC Medical Research Methodology, vol. 11, article no. 106. Open access 5 5
2010	Caughey, GE, Roughead, EE, Pratt, N, Shakib, S, Vitry, A I & Gilbert, AL 2010, 'Increased risk of hip fracture in the elderly associated with prochlorperazine: is a prescribing cascade contributing?', Pharmacoepidemiology and Drug Safety, vol. 19, no. 9, pp. 977-982. 43 38
2010	Lie, SA, Pratt, NL, Ryan, P, Engesaeter, LB, Havelin, L I, Furnes, O & Graves, S 2010, 'Duration of the increase in early postoperative mortality after elective hip and knee replacement', Journal of Bone and Joint Surgery: American Volume, vol. 92, no. 1, pp. 58-63. Open access 56 53
2010	Pratt, N 2010, 'Histamine H2 receptor antagonists and proton pump inhibitors: best options for gastro-oesophageal reflux in children', Drugs and Therapy Perspectives, vol. 26, no. 2, pp. 18-21.
2010	Pratt, N, Roughead, EE, Ryan, P & Gilbert, AL 2010, 'Differential impact of NSAIDs on rate of adverse events that require hospitalization in high-risk and general veteran populations: A retrospective cohort study', Drugs and Aging, vol. 27, no. 1, pp. 63-71. 22 16
2010	Pratt, N, Roughead, EE, Ryan, P & Salter, A 2010, 'Antipsychotics and the risk of death in the elderly : an instrumental variable analysis using two preference based instruments', Pharmacoepidemiology and Drug Safety, vol. 19, no. 7, pp. 699-707. 27 26
2010	Pratt, N, Roughead, EE, Salter, A & Ryan, P 2010, 'Factors associated with choice of antipsychotic treatment in elderly veterans: potential confounders for observational studies', Australian and New Zealand Journal of Public Health, vol. 34, no. 6, pp. 589-593. 5 5
2010	Pratt, NL, Roughead, EE, Ramsay, E, Salter, A & Ryan, P 2010, 'Risk of hospitalization for stroke associated with antipsychotic use in the elderly : a self-controlled case series', Drugs and Aging, vol. 27, no. 11, pp. 885-893. 29 31
2010	Roughead, EE, Barratt, JD, Ramsay, E, Pratt, N, Ryan, P, Peck, R, Killer, G & Gilbert, AL 2010, 'Collaborative home medicines review delays time to next hospitalization for warfarin associated bleeding in Australian war veterans', Journal of Clinical Pharmacy and Therapeutics.
2008	Conroy, J, Whitehouse, S, Graves, S, Pratt, N, Ryan, P & Crawford, R 2008, 'Risk Factors for Revision for Early Dislocation in Total Hip Arthroplasty', Journal of Arthroplasty, vol. 23, no. 6, pp. 867-872. 107 97
2008	Roughead, EE, Ramsay, E, Pratt, N & Gilbert, AL 2008, 'NSAID Use in individuals at risk of renal adverse events: An observational study to investigate trends in Australian veterans', Drug Safety, vol. 31, no. 11, pp. 997-1003. Open access 18 16

Reports

Year	Output
2018	Roughead, L, Kemp-Casey, A, Pratt, N & Nguyen, TA 2018, Methods to analyse medicine utilization and expenditure to support pharmaceutical policy implementation, World Health Organisation. Open access

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Advanced Digital Sciences Center	SINGAPORE
Ajou University	KOREA, REPUBLIC OF (SOUTH)
ANU College of Health & Medicine	AUSTRALIA
Astellas Pharma	JAPAN
Astellas Pharma (United States)	UNITED STATES
AstraZeneca PLC	UNITED STATES
Austin Health	AUSTRALIA
Australian Health Practitioner Regulation Agency	AUSTRALIA
Australian National University	AUSTRALIA
Australian Nursing and Midwifery Federation (SA Branch)	AUSTRALIA
Australian Orthopaedic Association	AUSTRALIA
Bond University	AUSTRALIA
Brigham and Women's Hospital	UNITED STATES
Brighton Collaboration	UNITED STATES
Columbia University	UNITED STATES
Columbia University Irving Medical Center	UNITED STATES
Columbia University Medical Centre	UNITED STATES
Cyberjaya University College of Medical Sciences	MALAYSIA
Department of Health and Ageing	AUSTRALIA
Department of Veterans Affairs	AUSTRALIA
Duke Clinical Research Institute	UNITED STATES
Duke University	UNITED STATES
Erasmus MC	NETHERLANDS
Erasmus University Rotterdam	NETHERLANDS
EWHA Womans University	KOREA, REPUBLIC OF (SOUTH)
Flinders University	AUSTRALIA
Food and Drug Administration	UNITED STATES
Georgia Tech College of Computing	UNITED STATES
Georgia Tech Research Institute	UNITED STATES
GlaxoSmithKline (Belgium)	BELGIUM
Government of South Australia	AUSTRALIA
Hamamatsu University	JAPAN
Hanyang University	KOREA, REPUBLIC OF (SOUTH)
Harvard University	UNITED STATES
Haukeland University Hospital	NORWAY
Health Canada	CANADA
Helping Hand Aged Care	AUSTRALIA
IMS Health	UNITED STATES
Institut Universitari d'Investigaci en Atenci Primria Jordi Gol	SPAIN
Institut Universitari d'Investigació en Atenció Primària Jordi Gol	SPAIN
IQVIA Inc.	UNITED STATES
Janssen R&D	UNITED STATES
Janssen Research & Development	UNITED STATES
Janssen Research and Development	BELGIUM
Jewish General Hospital	CANADA
Kaiser Permanente	GERMANY
Karolinska Institute	SWEDEN
Korea Institute of Drug Safety and Risk Management	KOREA, REPUBLIC OF (SOUTH)
McGill University	CANADA
Ministry of Health	INDIA
Monash University	AUSTRALIA
Monash University Malaysia	MALAYSIA
Murdoch Childrens Research Institute	AUSTRALIA
Musculoskeletal Australia	AUSTRALIA
National Cheng Kung University	TAIWAN
National Geriatric Hospital of Vietnam	VIET NAM
National Institutes of Health	UNITED STATES
National Yang-Ming University Taiwan	TAIWAN
NIH Clinical Center	UNITED STATES
NPO Drug Safety Research Unit	JAPAN
NPS MedicineWise	AUSTRALIA
Observational Health Data Sciences and Informatics	UNITED STATES
Odense University Hospital	DENMARK
Open University	UNITED KINGDOM
Oxford University	UNITED KINGDOM
Parliament House, Canberra	AUSTRALIA
Pfizer (United States)	UNITED STATES
Pharmacy Improvement Centre Ltd	AUSTRALIA
Prince Sattam Bin Abdulaziz University	SAUDI ARABIA
Private Individual	AUSTRALIA
Queensland University of Technology	AUSTRALIA
Real-World Evidence	SPAIN
Regenstrief Institute	UNITED STATES
Riyadh Elm University	SAUDI ARABIA
Royal Adelaide Hospital	AUSTRALIA
Rutgers University	UNITED STATES
Sanofi Pasteur	CANADA
Seoul National University	KOREA, REPUBLIC OF (SOUTH)
South Australian Health and Medical Research Institute (SAHMRI)	AUSTRALIA
Southern Cross Care (SA)	AUSTRALIA
St John of God Health Care	AUSTRALIA
Stanford University	UNITED STATES
Sung Kyun Kwan University	KOREA, REPUBLIC OF (SOUTH)
Swedish Hip Arthroplasty Register	SWEDEN
Taipei Medical University	TAIWAN
Taiwan Centers for Disease Control	TAIWAN
The Prince Charles Hospital	AUSTRALIA
Therapeutic Goods Administration	AUSTRALIA
Tohoku University Graduate School of Medicine	JAPAN
Tokyo University of Science	JAPAN
Ubon Ratchathani University	THAILAND
UCLA Fielding School of Public Health	UNITED STATES
University College London	UNITED KINGDOM
University of Adelaide	AUSTRALIA
University of British Columbia	CANADA
University of Calgary	CANADA
University of California	UNITED STATES
University of California System	UNITED STATES
University of California, Los Angeles	UNITED STATES
University of Colorado	UNITED STATES
University of Dundee	UNITED KINGDOM
University of Gothenburg	SWEDEN
University of Hong Kong	HONG KONG
University of Illinois at Chicago	UNITED STATES
University of Illinois at Urbana-Champaign	UNITED STATES
University of Manchester	UNITED KINGDOM
University of Manitoba	CANADA
University of Melbourne	AUSTRALIA
University of Messina	ITALY
University of Montreal	CANADA
University of New South Wales	AUSTRALIA
University of Newcastle	AUSTRALIA
University of North Carolina at Chapel Hill	UNITED STATES
University of Oxford	UNITED KINGDOM
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Southern California	UNITED STATES
University of Southern Denmark	DENMARK
University of Sydney	AUSTRALIA
University of Tasmania	AUSTRALIA
University of Technology Sydney	AUSTRALIA
University of Tokyo	JAPAN
University of Toronto	CANADA
University of Washington	UNITED STATES
University of Western Australia	AUSTRALIA
UNSW Sydney	AUSTRALIA
Uppsala Monitoring Centre	SWEDEN
Vanderbilt University	UNITED STATES
Veterans’ Medicines Advice and Therapeutics Education Services (Veterans’ MATES)	AUSTRALIA
Weill Cornell Medical College	UNITED STATES
Western Sydney University	AUSTRALIA
Yale School of Medicine	UNITED STATES
Yale University	UNITED STATES
Yonsei University College of Medicine	KOREA, REPUBLIC OF (SOUTH)

External engagement & recognition

Engagement/recognition	Year
Chief Investigator, Centre of Research Excellence National Health and Medical Research Council (NHMRC)	2017
Co-chair Asian Pharmacoepidemiology Network (AsPEN)	2017
Evaluation Leader, Veterans Medicines Advice and Therapeutics Education Service Department of Veterans Affairs (Veteran MATES), Australian Government	2017
Member International Society for Pharmacoepidemiology	2017
Member Statistical Society of Australia	2017
Member International Society for Environmental Epidemiology	2017
Winnovation Award for Science Women in Innovation	2015
Member, Advisory Committee on the Safety of Medicines Therapeutic Goods Administration, Department of Health, Australian Government	2013
Early Career Fellowship National Health and Medical Research Council (NHMRC)	2012
Early Career Researcher, Best Oral Presentation Health Services Research Association of Australia and New Zealand (HSRAANZ)	2011

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
Predictive Modelling for Safety Signal Detection with Biologic Medicines	Current
The prediction of drug-drug interactions in pharmaco-epidemiological databases using in silico molecular modelling techniques.	Current
An investigation of methods for developing clinical prediction models for time-to-event outcomes following joint replacement	Completed
Developing computational methods for detecting signals of adverse drug events from healthcare data	Completed
Developing data mining methods for detecting signals of adverse drug events	Completed
Enhancing Australia's pharmaco-surveillance capacity: a validation of sequence symmetry analysis method	Completed
Fixed dose combination medicine use in cardiovascular disease: implications for quality use of medicines and subsidy in Australia	Completed
How do Governments manage uncertainty about pharmaceutical evidence while maintaining a transparent and rigorous decision-making process for public reimbursement of pharmaceuticals?	Completed
Medicines and the risk of hip fracture among older people: an investigation of medicine safety in administrative claims data	Completed
Understanding frailty and its association with medicine use	Completed

Professor Nicole Pratt

About me

About me

UniSA Clinical & Health Sciences

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Highlights

Projects

Outputs

Highlights

Journal Articles

Reports

Current research & highlights

External engagement & recognition

Collaborations

Collaborations

External engagement & recognition

Chief Investigator, Centre of Research Excellence

Co-chair

Evaluation Leader, Veterans Medicines Advice and Therapeutics Education Service

Member

Member

Member

Winnovation Award for Science

Member, Advisory Committee on the Safety of Medicines

Early Career Fellowship

Early Career Researcher, Best Oral Presentation

Teaching & student supervision

Courses and programs

Research degree supervision

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