Peer has always been intrigued by implementation of novel technologies and methodologies with a goal to better understand the molecular mechanisms of human diseases. During his PhD at the department of human genetics of Radboud University Medical Center in Nijmegen (The Netherlands) he applied innovative technologies in the fields of genetics and immunology to show how genetic mutations can lead to different (immunological and developmental) disorders. In patient-focused research projects he has shown that disease gene identification is important for the diagnosis and clinical management of human (immunological) diseases. After finishing his PhD in 2017, Peer became a post-doctoral fellow in the research team of Professor Hamish Scott ... Read more
Making breakthrough discoveries in the fundamental causes of cancer, and translating these into prevention and treatment.
Peer has always been intrigued by implementation of novel technologies and methodologies with a goal to better understand the molecular mechanisms of human diseases. During his PhD at the department of human genetics of Radboud University Medical Center in Nijmegen (The Netherlands) he applied innovative technologies in the fields of genetics and immunology to show how genetic mutations can lead to different (immunological and developmental) disorders. In patient-focused research projects he has shown that disease gene identification is important for the diagnosis and clinical management of human (immunological) diseases. After finishing his PhD in 2017, Peer became a post-doctoral fellow in the research team of Professor Hamish Scott at the Centre for Cancer Biology (CCB) and the University of South Australia (UniSA). Within this research group they currently apply state-of-the-art multi-omics (genomics, transcriptomics) approaches to understand the pathogenesis of different diseases (mainly haematological malignancies and underlying genetic causes of perinatal death).
Doctor of Philosophy Radboud University Nijmegen
Bachelor of Applied Science University of Applied Sciences Utrecht
Excludes commercial-in-confidence projects.
Open access indicates that an output is open access.
Arts, P, Simons, A, Alzahrani, MS, Yilmaz, E & Hoischen, A and 47 other authors 2019, 'Exome sequencing in routine diagnostics: a generic test for 254 patients with primary immunodeficiencies', Genome Medicine: Medicine in the Post-Genomic Era, vol. 11, no. 1, article no. 38, pp. 1-15.
Open access 1 24
Byrne, AB, Arts, P, Polyak, SW, Feng, J, Schreiber, A, Kassahn, KS, Hahn, CN, Mordaunt, DA, Fletcher, JM, Lipsett, J, Bratkovic, D, Booker, GW, Smith, NJ & Scott, HS 2019, 'Identification and targeted management of a neurodegenerative disorder caused by biallelic mutations in SLC5A6', npj Genomic Medicine, vol. 4, no. 1, article number 28, pp. 1-8.
Arts, P, Van Der Raadt, J, Van Gestel, SH, Steehouwer, M, Shendure, J, Hoischen, A & Albers, CA 2017, 'Quantification of differential gene expression by multiplexed targeted resequencing of cDNA', Nature Communications, vol. 8, article number 15190, pp. 1-10.
Open access 3 3 11
Plantinga, T, Arts, P, Knarren, G, Mulder, A, Wakelkamp, I, Hermus, A, Joosten, L, Netea, M, Bisschop, P, de Herder, W, Beijers, H, de Bruin, I, Gilissen, C, Veltman, J, Hoischen, A, Smit, J & Netea-Maier, R 2017, 'Rare NOX3 variants confer susceptibility to agranulocytosis during thyrostatic treatment of Graves' disease', Clinical Pharmacology and Therapeutics, vol. 102, no. 6, pp. 1017-1024.
4 4 1
van der Kolk, NM, Arts, P, van Uden, IW, Hoischen, A, van de Veerdonk, FL, Netea, MG & de Jong, BA 2016, 'Progressive multifocal leukoencephalopathy in an immunocompetent patient', Annals of Clinical and Translational Neurology, vol. 3, no. 3, pp. 226-232.
Open access 9 10 1
Arts, P, Plantinga, T, van den Berg, J, Gilissen, C, Veltman, J, van Trotsenburg, A, van de Veerdonk, F, Kuijpers, T, Hoischen, A & Netea, M 2015, 'A missense mutation underlies defective SOCS4 function in a family with autoimmunity', Journal of Internal Medicine, vol. 278, no. 2, pp. 203-210.
6 5 1
Kumar, R, Corbett, MA, Smith, NJ, Jolly, LA, Arts, P & Gecz, J and 18 other authors 2014, 'Homozygous mutation of STXBP5L explains an autosomal recessive infantile-onset neurodegenerative disorder', Human Molecular Genetics, vol. 24, no. 7, article number ddu614, pp. 2000-2010.
Open access 4 4 4
Oosting, M, Cheng, SC, Bolscher, JM, Vestering-Stenger, R, Plantinga, TS, Verschueren, IC, Arts, P, Garritsen, A, Van Eenennaam, H, Sturm, P, Kullberg, BJ, Hoischen, A, Adema, GJ, Van Der Meer, JW, Netea, MG & Joosten, LA 2014, 'Human TLR10 is an anti-inflammatory pattern-recognition receptor', Proceedings of the National Academy of Sciences of USA, vol. 111, no. 12, pp. E4478-E4484.
Open access 118 112 7
Makrythanasis, P, van Bon, B, Steehouwer, M, Rodríguez-Santiago, B, Arts, P & Hoischen, A and 52 other authors 2013, 'MLL2 mutation detection in 86 patients with Kabuki syndrome: a genotype-phenotype study', Clinical Genetics: An International Journal of Genetics and Molecular Medicine, vol. 84, no. 6, pp. 539-545.
49 43 2
Smeekens, SP, Ng, A, Kumar, V, Johnson, MD, Arts, P & Xavier, RJ 2013, 'Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans', Nature Communications, vol. 4, article no. 1342, pp. 1-10.
Open access 86 86 1
Van De Veerdonk, FL, Plantinga, TS, Hoischen, A, Smeekens, SP, Joosten, LA, Gilissen, C, Arts, P, Rosentul, DC, Carmichael, AJ, Smits-van Der Graaf, CA, Kullberg, BJ, Van Der Meer, JW, Lilic, D, Veltman, JA & Netea, MG 2011, 'STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis', New England Journal of Medicine, vol. 365, no. 1, pp. 54-61.
366 328 13
Gilissen, C, Arts, HH, Hoischen, A, Spruijt, L, Mans, DA, Arts, P, Van Lier, B, Steehouwer, M, Van Reeuwijk, J, Kant, SG, Roepman, R, Knoers, NVAM, Veltman, JA & Brunner, HG 2010, 'Exome sequencing identifies WDR35 variants involved in Sensenbrenner syndrome', American Journal of Human Genetics.
Open access 211 195 6
Hoischen, A, Gilissen, C, Arts, P, Wieskamp, N, Van Vliet, WD, Vermeer, S, Steehouwer, M, De Vries, P, Meijer, R, Seiqueros, J, Knoers, NV, Buckley, MF, Scheffer, H & Veltman, JA 2010, 'Massively parallel sequencing of ataxia genes after array-based enrichment', Human Mutation, vol. 31, no. 4, pp. 492-499.
327 307 15
Nikopoulos, K, Gilissen, C, Hoischen, A, Erik van Nouhuys, C, Boonstra, FN, Blokland, EA, Arts, P, Wieskamp, N, Strom, TM, Ayuso, C, Tilanus, MA, Bouwhuis, S, Mukhopadhyay, A, Scheffer, H, Hoefsloot, LH, Veltman, JA, Cremers, FP & Collin, RW 2010, 'Next-generation sequencing of a 40 Mb linkage interval reveals TSPAN12 mutations in patients with familial exudative vitreoretinopathy', American Journal of Human Genetics, vol. 86, no. 2, pp. 240-247.
Open access 157 136 1
Vermeer, S, Hoischen, A, Meijer, RP, Gilissen, C, Arts, P & Knoers, N and 24 other authors 2010, 'Targeted next-generation sequencing of a 12.5 Mb homozygous region reveals ANO10 mutations in patients with autosomal-recessive cerebellar ataxia', American Journal of Human Genetics, vol. 87, no. 6, pp. 813-819.
Open access 76 68 3
Vissers, LELM, De Ligt, J, Gilissen, C, Janssen, I, Steehouwer, M, De Vries, P, Van Lier, B, Arts, P, Wieskamp, N, Del Rosario, M, Van Bon, BWM, Hoischen, A, De Vries, BBA, Brunner, HG & Veltman, JA 2010, 'A de novo paradigm for mental retardation', Nature Genetics, vol. 42, no. 12, pp. 1109-1113.
527 499 10
External engagement & recognition
|Academic Medical Centre||NETHERLANDS|
|Bartimeus Institute for the Visually Impaired||NETHERLANDS|
|Broad Institute of MIT and Harvard||UNITED STATES|
|Campbell University||UNITED STATES|
|Canisius Wilhelmina Hospital||NETHERLANDS|
|Council of Scientific and Industrial Research||INDIA|
|Donders Centre for Neuroscience||NETHERLANDS|
|Erasmus MC, Rotterdam||NETHERLANDS|
|Fundacion Jimenez Diaz||SPAIN|
|German Research Center for Environmental Health||GERMANY|
|James Cook University Hospital||UNITED KINGDOM|
|King Fahad Medical City||SAUDI ARABIA|
|Maastricht University Medical Centre||NETHERLANDS|
|Massachusetts General Hospital||UNITED STATES|
|Merck Research Laboratories||UNITED STATES|
|National Jewish Health||UNITED STATES|
|Newcastle University, United Kingdom||UNITED KINGDOM|
|Nijmegen Centre for Molecular Life Sciences - NCMLS||NETHERLANDS|
|Radboud University Medical Centre||NETHERLANDS|
|Radboud University Nijmegen||NETHERLANDS|
|Radboud University Nijmegen Medical Centre||NETHERLANDS|
|St Antonius Hospital||NETHERLANDS|
|Universitat Pompeu Fabra||SPAIN|
|University Medical Center Groningen||NETHERLANDS|
|University of Adelaide||AUSTRALIA|
|University of Amsterdam||NETHERLANDS|
|University of Geneva||SWITZERLAND|
|University of Porto||PORTUGAL|
|University of South Australia||AUSTRALIA|
|University of Washington||UNITED STATES|
|Women's and Children's Hospital||AUSTRALIA|