Professor Richard D'Andrea

Professor of Leukaemia Biology Centre for Cancer Biology

City West Campus (HB9-34)
tel +61 8 830 27830

email Richard.D'Andrea@unisa.edu.au

Research Degree Supervisor

About me

I am head of the Acute Leukaemia Laboratory at the Centre for Cancer Biology (UniSA), have extensive expertise in leukaemia biology, research leadership experience, and established clinical and industry networks. I have been a Program Leader at the Women’s and Children’s Health Research Institute and Chief Medical Scientist (Haematology/Oncology) at the Queen Elizabeth Hospital. I have held the Australian Research Council QEII Fellowship and the Peter Nelson Leukaemia Fellowship. My standing in the field of blood cancers is evident from >70 publications and my involvement in clinical trials and national and international studies on AML.

Centre for Cancer Biology

Making breakthrough discoveries in the fundamental causes of cancer, and translating these into prevention and treatment.

Tweets by @UniversitySA

Orcid
Scopus

Research

Research focus

Oncology and Carcinogenesis
Biochemistry and Cell Biology
Clinical Sciences
Cardiovascular Medicine and Haematology
Biological Sciences

Research

Projects

Excludes commercial-in-confidence projects.

Circular RNAs: Trojan Horses of Oncogenesis, NHMRC - Project Grant, 01/01/2018 - 31/12/2021
FANC gene mutations in Acute Myeloid Leukaemia biology and treatment, NHMRC - Project Grant, 01/01/2018 - 31/12/2021
Mab immunotherapies for myeloid leukemia patients with germline or somatic RUNX1 mutations., NHMRC - Project Grant, 01/01/2018 - 31/12/2020
The role of the GADD45A gene in AML pathogenesis, Cancer Council SA - Beat Cancer, 01/01/2018 - 31/12/2019
Novel orally available small molecule kinases inhibitors, Ray and Shirl Norman Cancer Research Trust, 31/03/2014 - 31/12/2017
Co-operation between GATA2 mutation or expression and RAS signalling in AML, NHMRC - Project Grant, 01/01/2015 - 31/12/2017
Formation and function of circular RNAs in human cells, NHMRC - Project Grant, 01/01/2015 - 31/12/2017
The role of the GADD45A gene in AML pathogenesis and response to therapy, Cancer Council SA - Beat Cancer, 01/01/2016 - 30/06/2017
The role of the GADD45A gene in AML pathogenesis and response to therapy, Royal Adelaide Hospital, 01/01/2016 - 31/03/2017
Targeting the EGFR and c-met tyrosine kinase receptors in myeloproliferative neoplasms, NHMRC - Project Grant, 01/01/2014 - 31/12/2016
Independent Validation and Investor Readiness for Cyclin-Dependent Kinase (CDK9), Bio Innovation SA, 01/01/2016 - 30/08/2016
Co-operating FLT3-ITD mutations, NHMRC - Project Grant, 01/07/2013 - 31/12/2015
Characterisation of a New Poor Risk Sub Category of Chronic Phase Chronic Myeloid Leukaemia (admin by Adelaide Uni), NHMRC - Project Grant, 01/07/2013 - 30/06/2015
Defining the leukaemogenic mechanism for GATA2 T354M, a new predisposing mutation in familial MDS/AML (admin by Adelaide Uni), Unknown, 01/07/2013 - 31/12/2014
GADD45A promoter methylation and poor prognosis in AML: mechanism and clinical significance, NHMRC - Project Grant, 01/07/2013 - 31/12/2014

Research

Outputs

Research outputs for the last seven years are shown below. To see earlier years visit ORCID or Scopus

Open access indicates that an output is open access.

Journal Articles

Year	Output
2021	Rapaport, F, Neelamraju, Y, Baslan, T, Hassane, D, D'Andrea, R & Garrett-Bakelman, FE and 18 other authors 2021, 'Genomic and evolutionary portraits of disease relapse in acute myeloid leukemia', Leukemia, vol. 35, no. 9, pp. 2688-2692. Open access 5
2021	Samaraweera, SE, Wang, PP, Li, KL, Casolari, DA, Feng, J, Maung, KZY, Scott, HS, Schreiber, AW, Brown, AL, Ross, DM, Gonda, TJ, Hahn, CN & D'Andrea, RJ and 13 other authors 2021, 'Childhood acute myeloid leukemia shows a high level of germline predisposition', Blood, vol. 138, no. 22, pp. 2293-2298.
2021	Singhal, D, Hahn, CN, Feurstein, S, Wee, LYA, Eshraghi, L, Schreiber, AW, Feng, J, Brown, AL, D'Andrea, RJ, Scott, HS & Hiwase, DK and 14 other authors 2021, 'Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer', Leukemia, vol. 35, pp. 3245-3256. 8 8 12
2021	Yusenko, M V, Trentmann, A, Casolari, DA, Abdel Ghani, L, Lenz, M, Horn, M, Dörner, W, Klempnauer, S, Mootz, HD, Arteaga, MF, Mikesch, JH, D'Andrea, RJ, Gonda, TJ, Müller-Tidow, C, Schmidt, TJ & Klempnauer, KH 2021, 'C/EBPβ is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute myeloid leukemia', Oncogene, vol. 40, no. 29, pp. 4746-4758. Open access 6 4 4
2020	Brown, AL, Arts, P, Babic, M, Dobbins, J, Feng, J, Ha, T, Homan, CC, King-Smith, SL, Li, X-C, Brautigan, P, Butcher, C, D'Andrea, RJ, Hahn, CN & Scott, HS and 46 other authors 2020, 'RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML', Blood Advances, vol. 4, no. 6, pp. pp. 1131-1144. Open access 38 38 3
2020	Salik, B, Yi, H, Hassan, N, Santiappillai, N, D'Andrea, RJ & Wang, JY and 15 other authors 2020, 'Targeting RSPO3-LGR4 signaling for leukemia stem cell eradication in acute myeloid leukemia', Cancer Cell, vol. 38, no. 2, pp. 263-278.e6. Open access 20 17 77
2019	Austin, RJ, Straube, J, Bruedigam, C, Pali, G, D'Andrea, R & Lane, SW and 15 other authors 2019, 'Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations', Leukemia, online, pp. 1-15. 15 15 56
2019	Chipurupalli, S, Kannan, E, Tergaonkar, V, D'Andrea, R & Robinson, N 2019, 'Hypoxia Induced ER Stress Response as an Adaptive Mechanism in Cancer', International Journal of Molecular Sciences, vol. 20, no. 3, pp. 1-17. Open access 47 44 2
2019	Iacobucci, I, Wen, J, Meggendorfer, M, Choi, JK, Lewis, ID, D'Andrea, RJ, Brown, AL, Scott, HS, Hahn, CN & Mullighan, CG 2019, 'Genomic subtyping and therapeutic targeting of acute erythroleukemia', Nature Genetics, vol. 51, no. 4, pp. 694-704. Open access 53 49 86
2019	Singhal, D, Wee, LYA, Kutyna, MM, Chhetri, R, Schreiber, AW, Feng, J, Branford, S, D'Andrea, RJ & Hiwase, D and 18 other authors 2019, 'The mutational burden of therapy-related myeloid neoplasms is similar to primary myelodysplastic syndrome but has a distinctive distribution', Leukemia, vol. 33, no.12, pp. 2842-2853. 20 19 3
2018	Beck, D, Thoms, J, Palu, C, Herold, T, Brown, A, Babic, M, Hahn, C, Perugini, M, Scott, H, Lewis, I, D'Andrea, R & Pimanda, J 2018, 'A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients', Leukemia, vol. 32, no. 2, pp. 263-272. Open access 23 22 2
2018	Chong, C-E, Venugopal, P, Stokes, P, Lee, Y, Brautigan, P, Yeung, D, Babic, M, Engler, G, Lane, S, Klingler-Hoffmann, M, Matthews, J, D'Andrea, R, Brown, A, Hahn, C & Scott, H 2018, 'Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes', Leukemia, vol. 32, no. 1, pp. 194-202. Open access 36 34 4
2018	Maung, KZY, Leo, PJ, Bassal, M, Casolari, DA, Bray, SC, Singhal, D, Samaraweera, SE, Nguyen, T, Cildir, G, Tergaonkar, V, Lewis, I, Brown, AL, D'Andrea, RJ & Gonda, TJ and 11 other authors 2018, 'Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia', Blood Cancer Journal, vol. 8, no. 6, article no. 50, pp. 1-5. Open access 12 12 3
2017	Casolari, D, Nguyen, T, Butcher, C, Iarossi, D, Hahn, C, Bray, S, Neufing, P, Parker, W, Feng, J, Maung, K, Wee, A, Vidovic, L, Kok, C, Bardy, P, Branford, S, Lewis, I, Lane, S, Scott, H, Ross, D & D'Andrea, R 2017, 'A novel, somatic, transforming mutation in the extracellular domain of epidermal growth factor receptor identified in myeloproliferative neoplasm', Scientific Reports, vol. 7, article no. 2467, pp. 1-9. Open access 4 4 3
2017	Powell, JA, Lewis, AC, Zhu, W, Toubia, J, Pitman, MR, Wallington-Beddoe, CT, Moretti, PA, Iarossi, D, Samaraweera, SE, Cummings, N, Ramshaw, HS, Thomas, D, Wei, AH, Lopez, AF, D'Andrea, RJ, Lewis, ID & Pitson, SM 2017, 'Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia', Blood, vol. 126, no. 6, pp. 771-782. Open access 49 48 85
2017	Sadras, T, Kok, CH, Perugini, M, Ramshaw, HS & D'Andrea, RJ 2017, 'miR-155 as a potential target of IL-3 signaling in primary AML cells', Leukemia Research, vol. 57, pp. 57-59. 6 6 1
2017	Venugopal, P, Moore, S, Lawrence, DM, George, AJ, Hannan, RD, Bray, SC, To, LB, D'Andrea, RJ, Feng, J, Tirimacco, A, Yeoman, AL, Young, CC, Fine, M, Schreiber, AW, Hahn, CN, Barnett, C, Saxon, B & Scott, HS 2017, 'Self-reverting mutations partially correct the blood phenotype in a diamond blackfan anemia patient', Haematologica: The Hematology Journal, vol. 102, pp. 506-509. Open access 15 15 15
2017	Wittwer, NL, Brumatti, G, Marchant, C, Sandow, JJ, Pudney, MK, Dottore, M, D'Andrea, RJ, Lopez, AF, Ekert, PG & Ramshaw, HS 2017, 'High CD123 levels enhance proliferation in response to IL-3, but reduce chemotaxis by downregulating CXCR4 expression', Blood Advances, vol. 1, no. 15, pp. 1067-1079. Open access 14 16 1
2016	Dawar, S, Shahrin, NH, Sladojevic, N, D'Andrea, R, Dorstyn, L, Hiwase, DK & Kumar, S 2016, 'Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice', Cell Death and Disease, vol. 7, no. e2509, pp.1-9. Open access 18 19 10
2016	Lewinsohn, M, Brown, AL, Weinel, LM, Phung, C, Chong, C-E, D'Andrea, RJ & Scott, HS and 23 other authors 2016, 'Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset, and lymphoid malignancies', Blood, vol. 127, no. 8, pp. 1017-1023. Open access 118 107 8
2016	Li, S, Garrett-Bakelman, FE, Chung, SS, Sanders, MA, Brown, AL, D'Andrea, RJ & Mason, CE and 26 other authors 2016, 'Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia', Nature Medicine, vol. 22, no. 7, pp. 792-802. Open access 206 203 62
2016	Lynch, JR, Yi, H, Casolari, DA, Voli, F, Gonzales-Aloy, E, Fung, TK, Liu, B, Brown, AL, Liu, T, Haber, M, Norris, MD, Lewis, ID, So, CWE, D'Andrea, RJD & Wang, JY 2016, 'Gaq signaling is required for the maintenance of MLL-AF9-induced acute myeloid leukemia', Leukemia, vol. 30, pp. 1745-1748. Open access 6 5 7
2016	Sadras, T, D'Andrea, RJ & White, DL 2016, 'The role of Wnt/β-Catenin signaling in normal and malignant hematopoiesis', vol. 1, no. 1, article no 1000103 pp. 1-9.
2016	Shahrin, NH, Diakiw, S, Dent, LA, Brown, AL & D'Andrea, RJ 2016, 'Conditional knockout mice demonstrate function of Klf5 as a myeloid transcription factor', Blood, vol. 128, no. 1, pp. 55-59. Open access 21 22 1
2016	Tiong, I, Casolari, D, Nguyen, T, Van Velzen, M, Ambler, K, D'Andrea, R & Ross, D 2016, 'Masked polycythaemia vera is genetically intermediate between JAK2V617F mutated essential thrombocythaemia and overt polycythaemia vera', Blood Cancer Journal, vol. 6, no. 8, pp. 1-3. Open access 4 2 1
2016	Tiong, IS, Casolari, DA, Moore, S, Nguyen, T, Van Velzen, MJ, Zantomio, D, Scott, HS, D'Andrea, RJ, Hahn, CN & Ross, DM 2016, 'Apparent 'JAK2-negative' polycythaemia vera due to compound mutations in exon 14', British Journal of Haematology, online, pp. 1-4. Open access 7 6
2015	Forristal, C, Brown, A, Helwani, F, Winkler, I, Nowlan, B, Barbier, V, Powell, R, Engler, G, Diakiw, S, Zannettino, A, Martin, S, Pattabiraman, D, D'Andrea, R, Lewis, I & Levesque, J 2015, 'Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML', Leukemia, vol. 29, no. 10, pp. 2075-2085. Open access 19 23 4
2015	Hahn, C, Ross, D, Feng, J, Beligaswatte, A, Hiwase, D, Parker, W, Ho, M, Zawitkowski, M, Ambler, K, Cheetham, G, Lee, Y, Babic, M, Butcher, C, Engler, G, Brown, A, D'Andrea, R, Lewis, I, Schreiber, A, To, L & Scott, H 2015, 'A tale of two siblings: two cases of AML arising from a single pre-leukemic DNMT3A mutant clone', Leukemia, vol. 29, no. 10, pp. 2101-2104. Open access 14 22
2014	Li, S, Garrett-Bakelman, F, Perl, AE, Luger, SM, Zhang, C, To, BL, Lewis, ID, Brown, AL, D'Andrea, RJ, Ross, EM, Levine, R, Carroll, M, Melnick, A & Mason, C 2014, 'Dynamic evolution of clonal epialleles revealed by methclone', Genome Biology, vol. 15, no. 9, article no. 472. Open access 42 46 9
2014	Sadras, T, Perugini, M, Kok, CH, Iarossi, DG, Heatley, SL, Brumatti, G, Samuel, MS, To, LB, Lewis, ID, Lopez, AF, Ekert, PG, Ramshaw, HS & D'Andrea, RJ 2014, 'Interleukin-3-mediated regulation of Beta-catenin in myeloid transformation and acute myeloid leukemia', Journal of Leukocyte Biology, vol. 96 no. 1, pp. 83-91. Open access 12 12
2013	Brumatti, G, Salmanidis, M, Kok, CH, Bilardi, RA, Sandow, JJ, Silke, N, Mason, K, Visser, J, Jabbour, AM, Glaser, SP, Okamoto, T, Bouillet, P, D'Andrea, RJ & Ekert, PG 2013, 'HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia', Oncotarget, vol. 4, no. 11, pp. 1933-1947. Open access 41 38
2013	Diakiw, S, D'Andrea, RJ & Brown, AL 2013, 'The double life of KLF5: opposing roles in regulation of gene-expression, cellular function, and transformation', IUBMB Life, vol. 65, no. 12, pp. 999-1011. Open access 36 32 1
2013	Diakiw, SM, Perugini, M, Kok, CH, Engler, GA, Cummings, N, To, LB, Wei, AH, Lewis, ID, Brown, AL & D'Andrea, RJ 2013, 'Methylation of KLF5 contributes to reduced expression in acute myeloid leukaemia and is associated with poor overall survival', British Journal of Haematology, vol. 161, no. 6, pp. 884-888. Open access 14 15 1
2013	Hercus, TR, Dhagat, U, Kan, WL, Broughton, SE, Nero, TL, Perugini, M, Sandow, JJ, D'Andrea, RJ, Ekert, PG, Hughes, T, Parker, MW & Lopez, AF 2013, 'Signalling by the βc family of cytokines', Cytokine and Growth Factor Reviews, vol. 24, no. 3, pp. 189-201. Open access 59 55
2013	Kok, C, Watkins, D, Leclercq, T, D'Andrea, R, Hughes, T & White, D 2013, 'Low GFI1 expression in white blood cells of CP-CML patients at diagnosis is strongly associated with subsequent blastic transformation', Leukemia, vol. 27, pp. 1427-1430. Open access 10 11
2013	Kok, CH, Brown, AL, Perugini, M, Iarossi, DG, Lewis, ID & D'Andrea, RJ 2013, 'The preferential occurrence of FLT3-TKD mutations in inv(16) AML and impact on survival outcome: a combined analysis of 1053 core-binding factor AML patients', British Journal of Haematology, vol. 160, no. 4, pp. 557-559. Open access 8 9
2013	Li, S, Garrett-Bakelman, FE, Akalin, A, Zumbo, P, Levine, R, To, BL, Lewis, I, Brown, AL, D'Andrea, RJ, Melnick, A & Mason, CE 2013, 'An optimized algorithm for detecting and annotating regional differential methylation', BMC Bioinformatics, vol. 14, no. S5, article no. s10, pp. 1-9. Open access 77 75 7
2013	Perugini, M, Iarossi, D, Kok, C, Cummings, N, Diakiw, S, Brown, A, Danner, S, Bardy, P, Bik, TL, Wei, A, Lewis, I & D'Andrea, R 2013, 'GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations', Leukemia, vol. 27, pp. 1588-1592. Open access 15 14
2013	Pishas, K I, Neuhaus, SJ, Clayer, MT, Schreiber, AW, Lawrence, DM, Perugini, M, Whitfield, RJ, Farshid, G, Manavis, J, Chyrssidis, S, Mayo, BJ, Haycox, RC, Ho, K, Brown, MP, D'Andrea, RJ, Evdokiou, A, Thomas, DM, Desai, J, Callen, DF & Neilsen, PM 2013, 'Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling', Cancer Research, vol. 74, no. 3, pp. 1-11. Open access 18 18 1
2013	Tan, P, Wei, A, Mithraprabhu, S, Cummings, N, Liu, H, Perugini, M, Reed, K, Avery, S, Patil, S, Walker, P, Mollee, P, Grigg, A, D'Andrea, R, Dear, A & Spencer, A 2013, 'Dual epigenetic targeting with panobinostat and azacitidine in acute myeloid leukemia and high-risk myelodysplastic syndrome', Blood Cancer Journal, vol. 4, article no. e170. Open access 80 76
2013	Watkins, D, Hughes, T, White, D & D'Andrea, R 2013, 'NPM1 mutations occur rarely or not at all in chronic myeloid leukaemia patients in chronic phase or blast crisis', Leukemia, vol. 27, pp. 489-490. Open access 10 8
2012	Bard-Chapeau, EA, Jeyakani, J, Kok, CH, Muller, J, Chua, BQ, Gunaratne, J, Batagov, A, Jenjaroenpun, P, Kuznetsov, VA, Wei, C-L, D'Andrea, RJ, Bourque, G, Jenkins, NA & Copeland, NG 2012, 'Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors', Proceedings of the National Academy of Sciences of USA, vol. 109, no. 6, pp. 2168-2173. Open access 63 60 4
2012	Brown, AL, Salerno, DG, Sadras, T, Engler, GA, Kok, CH, Wilkinson, CR, Samaraweera, SE, Sadlon, TJ, Perugini, M, Lewis, ID, Gonda, TJ & D'Andrea, RJ 2012, 'The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation', Differentiation, vol. 83, no. 1, pp. 47-59. Open access 14 13 3
2012	Diakiw, SM, Kok, CH, Bik, TL, Lewis, ID, Brown, AL & D'Andrea, RJ 2012, 'The granulocyte-associated transcription factor Krüppel-like factor 5 is silenced by hypermethylation in acute myeloid leukemia', Leukemia Research, vol. 36, no. 1, pp. 110-116. Open access 22 21
2012	Gagliardi, L, Ling, K, Kok, CH, Carolan, J, Brautigan, P, Kenyon, R, D'Andrea, RJ, Van Der Hoek, M, Hahn, CN, Torpy, D & Scott, H 2012, 'Genome-wide gene expression profiling identifies overlap with malignant adrenocortical tumours and novel mechanisms of inefficient steroidogenesis in familial ACTH-independent macronodular adrenal hyperplasia', Endocrine-Related Cancer, vol. 19, no. 3, pp. L19-L23. Open access 4 4 1
2012	Hercus, TR, Broughton, SE, Ekert, PG, Ramshaw, HS, Perugini, M, Grimbaldeston, M, Woodcock, JM, Thomas, D, Pitson, S, Hughes, T, D'Andrea, RJ, Parker, MW & Lopez, AF 2012, 'The GM-CSF receptor family: mechanism of activation and implications for disease', Growth Factors, vol. 30, no. 2, pp. 63-75. Open access 50 45 4
2012	Jabbour, AM, Gordon, L, Daunt, CP, Green, BD, Kok, CH, D'Andrea, R & Ekert, PG 2012, 'p53-dependent transcriptional responses to interleukin-3 signaling', PLoS One, vol. 7, no. 2, article no. e31428, pp. 1-11. Open access 7 7
2012	Rao, N, Butcher, CM, Lewis, ID, Ross, DM, Melo, J V, Scott, HS, Bardy, PG & D'Andrea, RJ 2012, 'Clonal and lineage analysis of somatic DNMT3A and JAK2 mutations in a chronic phase polycythemia vera patient', British Journal of Haematology, vol. 156, no. 2, pp. 268-270. Open access 8 10
2012	Wang, J, Hughes, T, Kok, C, Saunders, V, Frede, A, Groot-Obbink, K, Osborn, M, Somogyi, A, D'Andrea, RJ & White, D 2012, 'Contrasting effects of diclofenac and ibuprofen on active imatinib uptake into leukaemic cells', British Journal of Cancer, vol. 106, pp. 1772-1778. Open access 18 16 3
2012	White, DL, Brown, AL, D'Andrea, RJ & Rice, AM 2012, 'Unraveling the 'Known Unknowns': lessons and Reflections from the New Directions in Leukemia Research 2012 Conference', Cancer Research, vol. 72, no. 17, pp. 4300-4303. Open access 1
2011	Butcher, CM, Neufing, PJ, Eriksson, L, Carmichael, CL, Wilkins, EJ, Melo, J V, Lewis, ID, Bardy, PG, Scott, HS & D'Andrea, RJ 2011, 'RUNX1 mutations are rare in chronic phase polycythaemia vera', British Journal of Haematology, vol. 153, no. 5, pp. 672-675. Open access 2 2
2011	Hahn, CN, Chong, C-E, Carmichael, CL, Wilkins, EJ, Brautigan, PJ, Brown, AL, D'Andrea, RJ & Scott, HS and 20 other authors 2011, 'Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia', Nature Genetics, vol. 43, no. 10, pp. 1012-1019. Open access 412 382
2010	Hiwase, D, White, D, Powell, J, Saunders, V, Zrim, S, Frede, A, Guthridge, M, Lopez, A, D'Andrea, R, To, L, Melo, J, Kumar, S & Hughes, T 2010, 'Blocking cytokine signaling along with intense Bcr-Abl kinase inhibition induces apoptosis in primary CML progenitors', Leukemia, vol. 24, no. 4, pp. 771-778. Open access 45 40
2010	Kok, C, Brown, A, Ekert, P & D'Andrea, R 2010, 'Gene expression analysis reveals HOX gene upregulation in trisomy 8 AML', Leukemia, vol. 24, no. 6, pp. 1239-1243. Open access 13 12
2010	Perugini, M, Brown, AL, Salerno, DG, Booker, GW, Stojkoski, C, Hercus, TR, Lopez, AF, Hibbs, ML, Gonda, TJ & D'Andrea, RJ 2010, 'Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit', Blood, vol. 115, no. 16, pp. 3346-3353. Open access 47 45
2010	Perugini, M, Lee, H, McRae, S & D'Andrea, RJ 2010, 'Pharmacotherapy of chronic immune thrombocytopenicpurpura (ITP) with romiplostim', Clinical Medicine Reviews in Therapeutics, vol. 2010, no. 2, pp. 129-135. Open access
2010	Rawat, VP, Arseni, N, Ahmed, F, Mulaw, MA, Thoene, S, Heilmeier, B, Sadlon, T, D'Andrea, RJ, Hiddemann, W, Bohlander, SK, Buske, C & Feuring-Buske, M 2010, 'The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia', Proceedings of the National Academy of Sciences of USA, vol. 107, no. 39, pp. 16946-16951. Open access 22 20
2010	Sadlon, TJ, Wilkinson, BG, Pederson, S, Brown, CY, Bresatz, S, Gargett, T, Melville, EL, Peng, K, D'Andrea, RJ, Glonek, GG, Goodall, GJ, Zola, H, Shannon, MF & Barry, SC 2010, 'Genome-wide identification of human FOXP3 target genes in natural regulatory T cells', Journal of Immunology, vol. 185, no. 2, pp. 1071-1081. Open access 101 102
2009	Hutton, JF, Gargett, T, Sadlon, TJ, Bresatz, S, Brown, CY, Zola, H, Shannon, MF, D'Andrea, RJ & Barry, SC 2009, 'Development of CD4+CD25+FoxP3+ regulatory T cells from cord blood hematopoietic progenitor cells', Journal of Leukocyte Biology, vol. 85, no. 3, pp. 445-451. Open access 27 19
2009	Perugini, M, Kok, C, Brown, A, Wilkinson, C, Salerno, D, Young, S, Lewis, I, Gonda, T & D'Andrea, R 2009, 'Repression of Gadd45a by activated FLT3 and GM-CSF receptor mutants contributes to growth, survival and blocked differentiation', Leukemia, vol. 23, no. 4, pp. 729-738. Open access 17 16
2009	Perugini, M, Varelias, A, Sadlon, T & D'Andrea, RJ 2009, 'Hematopoietic growth factor mimetics: from concept to clinic', Cytokine and Growth Factor Reviews, vol. 20, no. 1, pp. 87-94. 23 25
2009	Powell, JA, Thomas, D, Barry, EF, Kok, CH, McClure, BJ, Tsykin, A, To, LB, Brown, A, Lewis, ID, Herbert, K, Goodall, GJ, Speed, TP, Asou, N, Jacob, B, Osato, M, Haylock, DN, Nilsson, SK, D'Andrea, RJ, Lopez, AF & Guthridge, MA 2009, 'Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML', Blood, vol. 114, no. 23, pp. 4859-4870. 50 48
2008	Butcher, CM, Hahn, U, To, L, Gecz, J, Wilkins, EJ, Scott, HS, Bardy, PG & D'Andrea, RJ 2008, 'Two novel JAK2 exon 12 mutations in JAK2V617F-negative polycythaemia vera patients', Leukemia, vol. 22, no. 4, pp. 870-873. Open access 60 58

External engagement & recognition

Collaborations

External engagement & recognition

Collaborations

Organisation	Country
Agency for Science, Technology and Research (A*STAR)	SINGAPORE
Austin Hospital	AUSTRALIA
Australian National University	AUSTRALIA
Cancer Institute NSW	AUSTRALIA
Child Health Research Institute	AUSTRALIA
Cornell University	UNITED STATES
Erasmus University Rotterdam	NETHERLANDS
Feil Family Brain and Mind Research Institute	UNITED STATES
Flinders Medical Centre	AUSTRALIA
Flinders University	AUSTRALIA
Hanson Centre for Cancer Research	AUSTRALIA
Hanson Institute	AUSTRALIA
Institute of Medical and Veterinary Science	AUSTRALIA
Institute of Medical and Veterinary Sciences	UNITED STATES
Institute of Molecular and Cell Biology, Singapore	SINGAPORE
JSS College of Pharmacy	INDIA
King's College London	UNITED KINGDOM
Kumamoto University	JAPAN
La Trobe University	AUSTRALIA
Ludwig Institute for Cancer Research	AUSTRALIA
Memorial Sloan Kettering Cancer Centre	UNITED STATES
Memorial Sloan-Kettering Cancer Center	UNITED STATES
MLL Münchner Leukämielabor GmbH	GERMANY
Monash University	AUSTRALIA
Murdoch Childrens Research Institute	AUSTRALIA
National University of Singapore	SINGAPORE
Osaka University	JAPAN
Peter MacCallum Cancer Centre	AUSTRALIA
Princess Alexandra Hospital	AUSTRALIA
QIMR Berghofer Medical Research Institute	AUSTRALIA
Queen Elizabeth Hospital	AUSTRALIA
Queensland Institute of Medical Research	AUSTRALIA
Queensland University of Technology	AUSTRALIA
Royal Adelaide Hospital	AUSTRALIA
Royal Children's Hospital	UNITED KINGDOM
Royal Melbourne Hospital	AUSTRALIA
Ruhr University Bochum	GERMANY
SA Pathology	AUSTRALIA
South Australian Health and Medical Research Institute (SAHMRI)	AUSTRALIA
St. Jude Children's Research Hospital	UNITED STATES
St. Vincent's Institute of Medical Research	AUSTRALIA
Stanford University	UNITED STATES
The Alfred Hospital	AUSTRALIA
Universiti Putra	MALAYSIA
University Hospital Heidelberg	GERMANY
University Hospital Ulm	GERMANY
University of Adelaide	AUSTRALIA
University of Chicago	UNITED STATES
University of Melbourne	AUSTRALIA
University of Muenster	GERMANY
University of Munich	GERMANY
University of Munich-Grosshadern	GERMANY
University of New South Wales	AUSTRALIA
University of Pennsylvania	UNITED STATES
University of Queensland	AUSTRALIA
University of South Australia	AUSTRALIA
University of Sydney	AUSTRALIA
University of Virginia	UNITED STATES
University of Western Australia	AUSTRALIA
VU University Medical Center	NETHERLANDS
Walter and Eliza Hall Institute of Medical Research	AUSTRALIA
Weill Cornell Medical College	UNITED STATES
Women and Children's Health Research Institute	CANADA
Women's and Children's Hospital	AUSTRALIA

Teaching & student supervision

Research degree supervision

Supervisions from 2010 shown

Thesis title	Student status
Structure-function relationships in nanoparticle genotoxiticty	Current
Investigating a novel CDK9 Inhibitor, CDKI-73, as a treatment for AML	Completed
Metabolic profiling of adult acute myeloid leukaemia (AML)	Completed
Pre-clinical development of a CDK inhibitor for the treatment of cancer	Completed
Targeting sphingosine kinase 1 in acute myeloid leukaemia	Completed

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Professor Richard D'Andrea

About me

About me

Centre for Cancer Biology

About me

Professional Associations

Experience

Qualifications

Research

Research focus

Projects

Outputs

Journal Articles

External engagement & recognition

Collaborations

Collaborations

Teaching & student supervision

Courses and programs

Research degree supervision

Gallery