I am head of the Acute Leukaemia Laboratory at the Centre for Cancer Biology (UniSA), have extensive expertise in leukaemia biology, research leadership experience, and established clinical and industry networks. I have been a Program Leader at the Women’s and Children’s Health Research Institute and Chief Medical Scientist (Haematology/Oncology) at the Queen Elizabeth Hospital. I have held the Australian Research Council QEII Fellowship and the Peter Nelson Leukaemia Fellowship. My standing in the field of blood cancers is evident from >70 publications and my involvement in clinical trials and national and international studies on AML.
About me
I am head of the Acute Leukaemia Laboratory at the Centre for Cancer Biology (UniSA), have extensive expertise in leukaemia biology, research leadership experience, and established clinical and industry networks. I have been a Program Leader at the Women’s and Children’s Health Research Institute and Chief Medical Scientist (Haematology/Oncology) at the Queen Elizabeth Hospital. I have held the Australian Research Council QEII Fellowship and the Peter Nelson Leukaemia Fellowship. My standing in the field of blood cancers is evident from >70 publications and my involvement in clinical trials and national and international studies on AML.
About me
Doctor of Philosophy (Biochemistry) The University of Adelaide
Bachelor of Science (Honours) The University of Adelaide
Bachelor of Science The University of Adelaide
Research
Excludes commercial-in-confidence projects.
Circular RNAs: Trojan Horses of Oncogenesis, NHMRC - Project Grant, 01/01/2018 - 31/12/2021
FANC gene mutations in Acute Myeloid Leukaemia biology and treatment, NHMRC - Project Grant, 01/01/2018 - 31/12/2021
Mab immunotherapies for myeloid leukemia patients with germline or somatic RUNX1 mutations., NHMRC - Project Grant, 01/01/2018 - 31/12/2020
The role of the GADD45A gene in AML pathogenesis, Cancer Council SA - Beat Cancer, 01/01/2018 - 31/12/2019
Novel orally available small molecule kinases inhibitors, Ray and Shirl Norman Cancer Research Trust, 31/03/2014 - 31/12/2017
Co-operation between GATA2 mutation or expression and RAS signalling in AML, NHMRC - Project Grant, 01/01/2015 - 31/12/2017
Formation and function of circular RNAs in human cells, NHMRC - Project Grant, 01/01/2015 - 31/12/2017
The role of the GADD45A gene in AML pathogenesis and response to therapy, Cancer Council SA - Beat Cancer, 01/01/2016 - 30/06/2017
The role of the GADD45A gene in AML pathogenesis and response to therapy, Royal Adelaide Hospital, 01/01/2016 - 31/03/2017
Targeting the EGFR and c-met tyrosine kinase receptors in myeloproliferative neoplasms, NHMRC - Project Grant, 01/01/2014 - 31/12/2016
Independent Validation and Investor Readiness for Cyclin-Dependent Kinase (CDK9), Bio Innovation SA, 01/01/2016 - 30/08/2016
Co-operating FLT3-ITD mutations, NHMRC - Project Grant, 01/07/2013 - 31/12/2015
Characterisation of a New Poor Risk Sub Category of Chronic Phase Chronic Myeloid Leukaemia (admin by Adelaide Uni), NHMRC - Project Grant, 01/07/2013 - 30/06/2015
Defining the leukaemogenic mechanism for GATA2 T354M, a new predisposing mutation in familial MDS/AML (admin by Adelaide Uni), Unknown, 01/07/2013 - 31/12/2014
GADD45A promoter methylation and poor prognosis in AML: mechanism and clinical significance, NHMRC - Project Grant, 01/07/2013 - 31/12/2014
Research
Research outputs for the last seven years are shown below. To see earlier years visit ORCID or Scopus
Open access indicates that an output is open access.
Year | Output |
---|---|
2021 |
Open access
5
|
2021 |
|
2021 |
8
8
12
|
2021 |
Open access
6
4
4
|
2020 |
Open access
38
38
3
|
2020 |
Open access
20
17
77
|
2019 |
15
15
56
|
2019 |
Open access
47
44
2
|
2019 |
Open access
53
49
86
|
2019 |
20
19
3
|
2018 |
Open access
23
22
2
|
2018 |
Open access
36
34
4
|
2018 |
Open access
12
12
3
|
2017 |
Open access
4
4
3
|
2017 |
Open access
49
48
85
|
2017 |
6
6
1
|
2017 |
Open access
15
15
15
|
2017 |
Open access
14
16
1
|
2016 |
Open access
18
19
10
|
2016 |
Open access
118
107
8
|
2016 |
Open access
206
203
62
|
2016 |
Open access
6
5
7
|
2016 |
|
2016 |
Open access
21
22
1
|
2016 |
Open access
4
2
1
|
2016 |
Open access
7
6
|
2015 |
Open access
19
23
4
|
2015 |
Open access
14
22
|
2014 |
Open access
42
46
9
|
2014 |
Open access
12
12
|
2013 |
Open access
41
38
|
2013 |
Open access
36
32
1
|
2013 |
Open access
14
15
1
|
2013 |
Open access
59
55
|
2013 |
Open access
10
11
|
2013 |
Open access
8
9
|
2013 |
Open access
77
75
7
|
2013 |
Open access
15
14
|
2013 |
Open access
18
18
1
|
2013 |
Open access
80
76
|
2013 |
Open access
10
8
|
2012 |
Open access
63
60
4
|
2012 |
Open access
14
13
3
|
2012 |
Open access
22
21
|
2012 |
Open access
4
4
1
|
2012 |
Open access
50
45
4
|
2012 |
Open access
7
7
|
2012 |
Open access
8
10
|
2012 |
Open access
18
16
3
|
2012 |
Open access
1
|
2011 |
Open access
2
2
|
2011 |
Open access
412
382
|
2010 |
Open access
45
40
|
2010 |
Open access
13
12
|
2010 |
Open access
47
45
|
2010 |
Open access
|
2010 |
Open access
22
20
|
2010 |
Open access
101
102
|
2009 |
Open access
27
19
|
2009 |
Open access
17
16
|
2009 |
23
25
|
2009 |
50
48
|
2008 |
Open access
60
58
|
External engagement & recognition
Organisation | Country |
---|---|
Agency for Science, Technology and Research (A*STAR) | SINGAPORE |
Austin Hospital | AUSTRALIA |
Australian National University | AUSTRALIA |
Cancer Institute NSW | AUSTRALIA |
Child Health Research Institute | AUSTRALIA |
Cornell University | UNITED STATES |
Erasmus University Rotterdam | NETHERLANDS |
Feil Family Brain and Mind Research Institute | UNITED STATES |
Flinders Medical Centre | AUSTRALIA |
Flinders University | AUSTRALIA |
Hanson Centre for Cancer Research | AUSTRALIA |
Hanson Institute | AUSTRALIA |
Institute of Medical and Veterinary Science | AUSTRALIA |
Institute of Medical and Veterinary Sciences | UNITED STATES |
Institute of Molecular and Cell Biology, Singapore | SINGAPORE |
JSS College of Pharmacy | INDIA |
King's College London | UNITED KINGDOM |
Kumamoto University | JAPAN |
La Trobe University | AUSTRALIA |
Ludwig Institute for Cancer Research | AUSTRALIA |
Memorial Sloan Kettering Cancer Centre | UNITED STATES |
Memorial Sloan-Kettering Cancer Center | UNITED STATES |
MLL Münchner Leukämielabor GmbH | GERMANY |
Monash University | AUSTRALIA |
Murdoch Childrens Research Institute | AUSTRALIA |
National University of Singapore | SINGAPORE |
Osaka University | JAPAN |
Peter MacCallum Cancer Centre | AUSTRALIA |
Princess Alexandra Hospital | AUSTRALIA |
QIMR Berghofer Medical Research Institute | AUSTRALIA |
Queen Elizabeth Hospital | AUSTRALIA |
Queensland Institute of Medical Research | AUSTRALIA |
Queensland University of Technology | AUSTRALIA |
Royal Adelaide Hospital | AUSTRALIA |
Royal Children's Hospital | UNITED KINGDOM |
Royal Melbourne Hospital | AUSTRALIA |
Ruhr University Bochum | GERMANY |
SA Pathology | AUSTRALIA |
South Australian Health and Medical Research Institute (SAHMRI) | AUSTRALIA |
St. Jude Children's Research Hospital | UNITED STATES |
St. Vincent's Institute of Medical Research | AUSTRALIA |
Stanford University | UNITED STATES |
The Alfred Hospital | AUSTRALIA |
Universiti Putra | MALAYSIA |
University Hospital Heidelberg | GERMANY |
University Hospital Ulm | GERMANY |
University of Adelaide | AUSTRALIA |
University of Chicago | UNITED STATES |
University of Melbourne | AUSTRALIA |
University of Muenster | GERMANY |
University of Munich | GERMANY |
University of Munich-Grosshadern | GERMANY |
University of New South Wales | AUSTRALIA |
University of Pennsylvania | UNITED STATES |
University of Queensland | AUSTRALIA |
University of South Australia | AUSTRALIA |
University of Sydney | AUSTRALIA |
University of Virginia | UNITED STATES |
University of Western Australia | AUSTRALIA |
VU University Medical Center | NETHERLANDS |
Walter and Eliza Hall Institute of Medical Research | AUSTRALIA |
Weill Cornell Medical College | UNITED STATES |
Women and Children's Health Research Institute | CANADA |
Women's and Children's Hospital | AUSTRALIA |
Teaching & student supervision
Supervisions from 2010 shown
Thesis title | Student status |
---|---|
Structure-function relationships in nanoparticle genotoxiticty | Current |
Investigating a novel CDK9 Inhibitor, CDKI-73, as a treatment for AML | Completed |
Metabolic profiling of adult acute myeloid leukaemia (AML) | Completed |
Pre-clinical development of a CDK inhibitor for the treatment of cancer | Completed |
Targeting sphingosine kinase 1 in acute myeloid leukaemia | Completed |