I have a background in pharmacy and natural products chemistry. My research interests include Australian medicinal and food plants with an emphasis on research which is in partnership with Australian Aboriginal communities and driven by the communities themselves. Currently my work involves collaborative research projects with communities in Queensland and South Australia examining the health benefits of, and product development from, some traditional medicinal and food plants. We focus on plants with antibacterial, anti-inflammatory and anti-diabetic activities.
I also collaborate with researchers at the University of Copenhagen in Denmark and Shandong University in China. I am a member of the “Desert-loving Therapeutics” project team. Led ... Read more
About me
I have a background in pharmacy and natural products chemistry. My research interests include Australian medicinal and food plants with an emphasis on research which is in partnership with Australian Aboriginal communities and driven by the communities themselves. Currently my work involves collaborative research projects with communities in Queensland and South Australia examining the health benefits of, and product development from, some traditional medicinal and food plants. We focus on plants with antibacterial, anti-inflammatory and anti-diabetic activities.
I also collaborate with researchers at the University of Copenhagen in Denmark and Shandong University in China. I am a member of the “Desert-loving Therapeutics” project team. Led by Professor Birger Møller of the Plant Biochemistry Laboratory, University of Copenhagen, this interdisciplinary project brings together botany, taxonomy, evolutionary phylogeny, plant chemistry and pharmacology to understand the chemistry and bioactivity of the Australian plant genus Eremophila. Thorough this project we are looking at models of equitable benefit-sharing and the establishment of a Trust to fund projects driven by Indigenous communities and organisations.
I collaborate with natural products researchers and medicinal chemists at Shandong University. These projects use both natural and synthetic chemistry approaches to find new antibacterial compounds.
I have also conducted research in the areas of complementary medicine use in the community and medication safety
About me
Royal Australian Chemical Institute: North Melbourne, Victoria, Australia
Australian Society for Microbiology: VIC, Australia
American Chemical Society: Washington, DC, US
About me
Doctor of Philosophy (Health Sciences) University of South Australia
Bachelor of Pharmacy University of South Australia
2014 (to Present) Senior Research Fellow (0.5-0.6 FTE), Quality Use of Medicines and Pharmacy Research Centre & School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia
2005 – 2013 Research Fellow, Quality Use of Medicines and Pharmacy Research Centre, Sansom Institute for Health Research, University of South Australia, Adelaide, Australia (0.5 FTE 2009-2014)
2002 - 2005 Research Associate Quality Use of Medicines and Pharmacy Research Centre, Sansom Institute, University of South Australia
1999-2001 Research Assistant, Quality Use of Medicines and Pharmacy Research Centre, University of South Australia
1995-1999 Lecturer and tutor (Casual), School of Pharmacy and Medical Sciences
1993-1994 Clinical trial co-ordinator, Gastroenterology Department, Women’s and Children’s Hospital, Adelaide
Research
Excludes commercial-in-confidence projects.
Development of antibacterial and anti-inflammatory compounds, Wound Management Innovation CRC, 01/09/2013 - 31/12/2016
RP2.13 - Optimised serrulatane bioactives from Eremophila plants, Wound Management Innovation CRC, 01/07/2013 - 30/12/2016
Investigation of new anti-bacterials from Australian medicinal plants, James N Kirby Foundation, 01/07/2014 - 30/09/2015
Research
Research outputs for the last seven years are shown below. To see earlier years visit ORCID, ResearcherID or Scopus
Open access indicates that an output is open access.
Year | Output |
---|---|
2022 |
Open access
|
2021 |
Open access
4
4
50
|
2021 |
Open access
117
|
2020 |
2
3
|
2020 |
7
8
|
Year | Output |
---|---|
2015 |
1
|
2012 |
Open access
|
Year | Output |
---|---|
2022 |
Open access
|
2022 |
Open access
|
2022 |
Open access
2
1
84
|
2022 |
Open access
|
2022 |
Open access
|
2022 |
Open access
|
2021 |
Open access
4
4
50
|
2021 |
3
3
1
|
2021 |
|
2021 |
2
3
1
|
2021 |
Open access
117
|
2020 |
Open access
5
5
2
|
2020 |
2
3
|
2020 |
7
8
|
2020 |
5
5
1
|
2020 |
10
7
|
2020 |
6
7
|
2019 |
Open access
5
3
1
|
2019 |
8
5
1
|
2018 |
19
18
1
|
2018 |
5
4
|
2018 |
18
18
|
2018 |
10
9
|
2017 |
Open access
2
1
|
2017 |
25
23
|
2017 |
3
4
2
|
2017 |
10
9
9
|
2017 |
14
14
|
2016 |
Open access
13
11
31
|
2016 |
Open access
24
23
5
|
2016 |
Open access
83
69
10
|
2016 |
Open access
4
4
4
|
2015 |
Open access
17
18
19
|
2015 |
10
8
12
|
2015 |
Open access
6
6
|
2014 |
Open access
17
16
|
2013 |
Open access
11
10
|
2012 |
Open access
29
28
|
2012 |
11
11
|
2012 |
Open access
15
14
|
2011 |
27
25
|
2011 |
17
14
|
2010 |
|
2010 |
28
26
|
2009 |
Open access
83
72
|
2009 |
73
66
|
2009 |
Open access
140
|
2009 |
Open access
38
|
2008 |
|
2008 |
Open access
|
2008 |
Open access
7
6
|
Year | Output |
---|---|
2020 |
Open access
|
2019 |
Open access
|
Research
Research
Details | Registry | Status |
---|---|---|
Semple, Susan J; Simpson, Bradley S; McKinnon, Ross Allan; Claudie, David; Gerber, Jacobus P; Wang, Jiping; Moreton, George Sr |
EP | Filed |
Semple, Susan J; Simpson, Bradley S; McKinnon, Ross Allan; Claudie, David; Gerber, Jacobus P; Wang, Jiping; Moreton, George Sr |
US | Filed |
Semple, Susan J; Simpson, Bradley S; McKinnon, Ross Allan; Claudie, David; Gerber, Jacobus P; Wang, Jiping; Moreton, George Sr |
WO | Filed |
Griesser, Hans Jörg; Ndi, Chi Pius; Semple, Susan Jean; Ys, Hardi |
WO | Filed |
External engagement & recognition
Organisation | Country |
---|---|
Ayurvedic Government Medical College | INDIA |
Chuulangun Aboriginal Corporation | AUSTRALIA |
Flinders Medical Centre | AUSTRALIA |
Flinders University | AUSTRALIA |
Monash University | AUSTRALIA |
Nelumbo Botaniks | AUSTRALIA |
Qingdao University | CHINA |
ReaLi Tide Biological Technology (Weihai) Co. Ltd | CHINA |
Robert Mathys Stiftung | SWITZERLAND |
Royal Botanic Gardens Melbourne | AUSTRALIA |
Shandong Center for Disease Control and Prevention | CHINA |
Shandong University | CHINA |
State Herbarium of South Australia | AUSTRALIA |
Technical University of Denmark | DENMARK |
University of Adelaide | AUSTRALIA |
University of Copenhagen | DENMARK |
University of Melbourne | AUSTRALIA |
University of Queensland | AUSTRALIA |
University of South Australia | AUSTRALIA |
University of Western Australia | AUSTRALIA |
Wise Owl Consulting | AUSTRALIA |
Zaozhuang University | CHINA |
External engagement & recognition
Engagement/recognition | Year |
---|---|
Research models for benefit sharing with an Aboriginal groupQueensland Government (review of Biodiscovery Act) |
2019 |
Keynote speaker APSA Lecture at annual conferenceAustralasian Pharmaceutical Science Association (APSA) |
2018 |
Teaching & student supervision
Supervisions from 2010 shown
Thesis title | Student status |
---|---|
Antimicrobial resistance and antimicrobial drug development | Current |
Preventing chronic infection in Cystic Fibrosis patients with a repurposed drug that inhibits antibiotic efflux pumps | Current |
A combined in silico and microbiological approach for the identification of novel efflux pump inhibitors against AcrAB-TolC | Completed |
Advanced glycation end product induced genotoxicity and receptor expression in human cells | Completed |
Antibacterial coatings for biomedical devices by covalent grafting of serrulatane diterpenes | Completed |
Antibacterial serrulatanes: synthetic studies and structure-activity relationships | Completed |
Biological actions of antibacterial compounds covalently attached onto solid material surfaces or released diffusively from materials | Completed |
Chemical and pharmacological investigation of Acacia and Santalum species | Completed |
Chemical and pharmacological investigation of Dodonaea polyandra | Completed |
Discovery of antibacterial compounds from Australian Eremophila plants | Completed |
Pharmacological and in silico investigation of anti-inflammatory diterpenoid compounds isolated from Dodonaea polyandra | Completed |
Serrulatanes from eremophila neglecta: their spectrum of antibacterial activity, cytotoxicity and mode of action | Completed |
Spatial and molecular aspects of hemiparasites on Acacia spp. | Completed |
Targeting bacterial cellular division via FtsZ as an approach in the development of new antimicrobial agents | Completed |